BioRxiv 2024-12-09 Papers
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 混合交配系统中的中性遗传多样性 | Uyenoyama, M. K. | N/A | Neutral genetic diversity in mixed mating systems | |
| 早期生活压力引发与恐惧泛化相关的持续性星形胶质细胞功能障碍。 | Guayasamin, M. | N/A | Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation | |
| 撤回：增强突变热点预测：原子波动的作用 | Martis, E. A. F. | N/A | WITHDRAWN: Enhancing Mutational Hotspot Predictions: The Role of Atomic Fluctuations | |
| 使用在横截面数据上预训练的规范模型来评估神经影像数据中的个体内部纵向变化 | Rehak Buckova, B. | N/A | Using normative models pre-trained on cross-sectional data to evaluate intra-individual longitudinal changes in neuroimaging data | |
| 细胞膜通过胆固醇不对称性维持磷脂不平衡 | Doktorova, M. | N/A | Cell Membranes Sustain Phospholipid Imbalance Via Cholesterol Asymmetry | |
| QInfoMating：性选择与选型交配估计软件 | Carvajal-Rodriguez, A. | N/A | QInfoMating: Sexual Selection and Assortative Mating Estimation Software | |
| HERV的激活将ME/CFS与纤维肌痛区分开来，同时定义了一个新的疾病分类实体。 | Gimenez-Orenga, K. | N/A | HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity | |
| 基于文库的单细胞RNA测序中辅助性T细胞亚群的映射与时间追踪 | Lukyanov, D. K. | N/A | Repertoire-based mapping and time-tracking of helper T cell subsets in scRNA-Seq | |
| 睾酮诱导的精囊上皮细胞代谢变化会改变血浆成分，从而增强精子生育能力。 | Yamanaka, T. | N/A | Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Fertility | |
| 来自辐射杂交和CRISPRi的互补人类基因相互作用图谱 | Smith, D. J. | N/A | Complementary human gene interaction maps from radiation hybrids and CRISPRi | |
| 肾小球弹性与基因表达模式定义了Alport肾病的两个阶段 | Yoon, J. | N/A | Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy | |
| MdfA是一种新型的ClpC适配蛋白，在枯草芽孢杆菌孢子的发育过程中发挥作用。 | Massoni, S. C. | N/A | MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore | |
| 特定PIP2亚型组成的识别触发了别构控制机制，该机制用于选择性膜定位内质网固醇转运蛋白StarD4的货物装载和释放功能。 | Xie, H. | N/A | Recognition of specific PIP2-subtype composition triggers the allosteric control mechanism for selective membrane targeting of cargo loading and release functions of the intracellular sterol transporter StarD4 | |
| 在羊膜动物原肠胚形成过程中，左右组织者形成之前，双侧细胞流动呈现出不对称性。 | Asai, R. | N/A | Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation | |
| 视觉的第一个突触处存在一种异质性群体编码 | Herzog, T. | N/A | A heterogeneous population code at the first synapse of vision | |
| 通过生成式深度学习对高度动态蛋白质的构象集合进行采样 | Ruzmetov, T. | N/A | Sampling Conformational Ensembles of Highly Dynamic Proteins via Generative Deep Learning | |
| 将翻译后的数字数据编码到哺乳动物细胞群体的基因组中 | Callisto, A. | N/A | Post-translational digital data encoding into the genomes of mammalian cell populations | |
| 从解剖学角度来看，大脑皮层通过慢速（1-8Hz）和快速（70-120Hz）振荡活动对音乐和语言进行不同的追踪。 | Osorio, S. | N/A | Anatomically distinct cortical tracking of music and speech by slow (1-8Hz) and fast (70-120Hz) oscillatory activity | |
| 在小麦根际中，假单胞菌的分类和功能微多样性是因品种而异的，并且与抗病性特征和根直径有关。 | Herms, C. H. | N/A | Pseudomonas taxonomic and functional microdiversity in the wheat rhizosphere is cultivar-dependent and links to disease resistance profile and root diameter | |
| Oviductin决定了哺乳动物透明带（zona pellucida）的种属特异性。 | de la Fuente, D. | N/A | Oviductin sets the species-specificity of the mammalian zona pellucida | |
| 一个动力学简单行走模型修正了恢复率的定义：人类行走在大支撑阶段与摆动运动有显著偏离 | Hosseini-Yazdi, S.-S. | N/A | A Powered Simple Walking Model Modifies the Rate of Recovery Definition: Human Walking Deviates Drastically from Pendular Motion During the Double Support Phase | |
| 通过非自主元件的调控来维持长期的可转座元件活性 | Omole, A. D. | N/A | Maintenance of long-term transposable element activity through regulation by nonautonomous elements | |
| 天蝎座：增强嵌入以改善DNA序列的下游分析 | Refahi, M. | N/A | Scorpio : Enhancing Embeddings to Improve Downstream Analysis of DNA sequences | |
| 质心工作分析估计不同行走条件下的首选步行速度 | Hosseini-Yazdi, S.-S. | N/A | Center of Mass Work Analysis Estimates Preferred Walking Speeds for Varying Walking Conditions | |
| 解耦冠状病毒Nsp1的功能角色 | Baeumlin, E. | N/A | Uncoupling the functional roles of Coronavirus Nsp1 | |
| 定期更新的基准数据集，用于对AlphaFold应用进行统计正确的评估 | Dobson, L. | N/A | Regularly updated benchmark sets for statistically correct evaluations of AlphaFold applications | |
| 重新审视脑脊液的等效光学特性以提高基于扩散的大脑建模精度 | Lewis, A. | N/A | Revisiting equivalent optical properties for cerebrospinal fluid to improve diffusion-based modeling accuracy in the brain | |
| 碳酸酐酶抑制剂可预防脑淀粉样变性模型中无症状的毛细血管血流紊乱。 | Gutierrez-Jimenez, E. | N/A | Carbonic anhydrase inhibitors prevent presymptomatic capillary flow disturbances in a model of cerebral amyloidosis | |
| 功能失调的机械传导调节了PIK3CA驱动的血管畸形的进展 | Aw, W. Y. | N/A | Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations | |
| 使用深度学习在冷冻电镜和X射线图中识别配体 | Karolczak, J. | N/A | Ligand Identification in CryoEM and X-ray Maps Using Deep Learning | |
| 响应多样性是复杂食物网中时间稳定性的主要驱动力。 | Danet, A. | N/A | Response diversity is a major driver of temporal stability in complex food webs | |
| 高数据率大分子晶体学（HDRMX）的大规模压缩：对衍射数据及后续结构分析的影响 | Bernstein, H. J. | N/A | Massive Compression for High Data Rate Macromolecular Crystallography (HDRMX): Impact on Diffraction Data and Subsequent Structural Analysis | |
| 物体非刚性各向异性：皮层各向异性对高级知觉的影响 | Maruya, A. | N/A | Anisotropy of object nonrigidity: High-level perceptual consequences of cortical anisotropy | |
| 运动学习利用协调的低频皮层-基底神经节活动来优化帕金森病患者运动准备 | Presbrey, K. N. | N/A | Motor learning leverages coordinated low-frequency cortico-basal ganglia activity to optimize motor preparation in humans with Parkinson's Disease | |
| 利用蚂蚁共生体制作酸奶揭示了用于食品发酵的细菌、酸和酶。 | Sinotte, V. M. | N/A | Making yogurt with the ant holobiont uncovers bacteria, acids, and enzymes for food fermentation | |
| 使用静息态fMRI的因果关系映射揭示了精神分裂症患者的高活动性和低连接性 | Tahir, A. | N/A | Causality Mapping Using Resting-state fMRI Reveals Hyperactivity and Hypoconnectivity in Schizophrenia Patients | |
| 抑制性可塑性调控中时间精度与效应幅度之间的权衡决定了学习表征的可分离性。 | Rubisch, P. | N/A | The trade-off between temporal precision and effect amplitude of inhibitory plasticity regulation determines separability of learned representations | |
| 在营养生长期暴露于高pH胁迫下的豌豆中的转录重编程与微生物群动态 | Thapa, A. | N/A | Transcriptional reprogramming and microbiome dynamics in garden pea exposed to high pH stress during vegetative stage | |
| 在感染猿猴免疫缺陷病毒（SIV）的恒河猴中，大麻素能够改变基底神经节的miRNA m6A甲基化谱，使其趋向于抗炎表型。 | Okeoma, C. M. | N/A | Cannabinoids shift the basal ganglia miRNA m6A methylation profile towards an anti-inflammatory phenotype in SIV-infected Rhesus macaques | |
| 鉴定和靶向气道上皮细胞中SARS-CoV-2-宿主相互作用的调节因子。 | Dirvin, B. G. | N/A | Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium. | |
| 在嗜盐碱杆菌（Haloferax volcanii）的生长周期中，古菌微管蛋白样蛋白CetZ1和CetZ2对细胞形态具有相反的影响。 | Brown, H. J. | N/A | Archaeal tubulin-like proteins CetZ1 and CetZ2 have opposing effects on cell morphology during the growth cycle of Haloferax volcanii | |
| 全小鼠肾小球纳米级光学成像、重建与空间分析 | Ali, A. | N/A | Nanoscale Optical Imaging, Reconstruction, and Spatial Analysis of Whole Mouse Glomeruli | |
| Kauffman模型中闭合与开放式进化之间因果关系的证据 | Faggian, M. F. | N/A | Evidence of causality between Closure and Open-Ended Evolution in the Kauffman model | |
| 皮质层次结构中神经编码的变化：从稀有的类别性到始终的高维度 | Posani, L. | N/A | Rarely categorical, always high-dimensional: how the neural code changes along the cortical hierarchy | |
| 卵巢生殖干细胞的去分化是依赖于细胞突的。 | Sutcliffe, C. | N/A | Ovarian germline stem cell dedifferentiation is cytoneme-dependent | |
| 侧孢曲霉：一种在日本新出现的隐匿性曲霉病病原体 | Shibata, S. | N/A | Aspergillus latus: a cryptic causative agent of aspergillosis emerging in Japan | |
| 在高维数据空间中，是使用更多的潜在变量还是更少的潜在变量？这就是问题所在。 | Vaccari, F. E. | N/A | More or fewer latent variables in the high-dimensional data space? That is the question | |
| CAFE：一种集成式网络应用程序，用于光谱流式细胞术中的高维数据分析与可视化 | Siam, M. H. B. | N/A | CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry | |
| 自发脑活动背后的神经受体和转运蛋白 | Nakuci, J. | N/A | The neuroreceptors and transporters underlying spontaneous brain activity | |
| 一种心血管-肾脏-代谢综合征的小鼠模型显示，在缺血的后肢中，肢体功能受损。 | Chitalia, V. | N/A | A murine model of cardiovascular-kidney-metabolic syndrome demonstrates compromised limb function in the ischemic hind limb | |
| 元预测扩展了人类大脑皮层和皮层下区域的奖励学习机制。 | Shin, J. | N/A | Meta-prediction extends human cortical and subcortical reward learning | |
| 重复节奏模式有助于音乐节拍的神经表征 | Coulon, E. | N/A | Repetition of Rhythmic Patterns Fosters Neural Representation of Musical Meter | |
| 将人类基因组演化的历程进行划分 | Pagani, L. | N/A | Partitioning the genomic journey to becoming Homo sapiens | |
| CCNB1IP1顺式调控的进化推动了灵长类动物皮层大小和折叠程度的逐渐增加 | Hu, T. | N/A | Cis-Regulatory Evolution of CCNB1IP1 Driving Gradual Increase of Cortical Size and Folding in primates | |
| 超越二分法：大鼠超声波发声的多样性 | Wada, R. | N/A | Beyond dichotomy: diversity of rat's ultrasonic vocalizations | |
| 人类对声音而非触觉节奏的行为相关分段神经表征 | Lenoir, C. | N/A | Behavior-relevant periodized neural representation of acoustic but not tactile rhythm in humans | |
| 与帕金森病相关的Pink1缺失会破坏包裹性胶质细胞中的囊泡运输，导致多巴胺能神经元突触丧失。 | Ghezzi, L. | N/A | Parkinson's disease-associated Pink1 loss disrupts vesicle trafficking in ensheathing glia causing dopaminergic neuron synapse loss | |
| 基于PDMS的微流控芯片组件的时间分辨冷冻电镜（TRCEM）样品制备 | Feng, X. | N/A | Time-resolved cryo-EM (TRCEM) sample preparation using a PDMS-based microfluidic chip assembly | |
| 通过冷冻电镜揭示的自然华丽的仅由RNA组成的复合物 | Kretsch, R. C. | N/A | Naturally ornate RNA-only complexes revealed by cryo-EM | |
| 利用淋巴结探寻者64Cu标记的革兰氏阴性菌外泌体进行脑脊液淋巴引流PET成像 | Kim, K. | N/A | Lymphatic drainage of cerebrospinal fluid using lymph node seeker 64Cu-labeled Gram-negative bacterial extracellular vesicles PET | |
| mTOR信号通路通过S6K1-RhoA和aPKC-Lgl2轴调控上皮细胞顶端突起的形成。 | Sen, S. | N/A | mTOR signaling governs the formation of epithelial apical projection via S6K1-RhoA and aPKC-Lgl2 axes | |
| 生成用于研究精子中线粒体的转基因小鼠模型 | Sarkar, H. | N/A | Generation of a Transgenic Mouse Model for Investigating Mitochondria in Sperm | |
| 通过联合过表达筛选，我们发现PIPPI是一种与内质网应激反应相关的新型微蛋白。 | Lafranchi, L. | N/A | Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response | |
| 细胞体积调控培养的人表皮角质形成细胞的终末分化 | Watt, F. M. | N/A | Cell volume regulates terminal differentiation of cultured human epidermal keratinocytes | |
| 人类白细胞中细胞类型特异性的自噬 | Dang, L. | N/A | Cell-type specific autophagy in human leukocytes | |
| 微纤维模板孔凝胶生物墨水实现管状界面及微血管化，直至3D生物打印的基本构建单元 | Guo, Y. | N/A | Microfiber-Templated Porogel Bioinks Enable Tubular Interfaces and Microvascularization Down to the Building Blocks for 3D Bioprinting | |
| 脂质的恒定pH分子动力学模拟 | Trollmann, M. F. W. | N/A | Constant-pH MD Simulations of Lipids | |
| 人CFTR开放状态的结构和氯离子传导特性 | Zeng, Z. W. | N/A | Structure and Cl-Conductance Properties of the Open State of Human CFTR | |
| TRIM5α PRYSPRY结构域与HIV衣壳无序相互作用界面的全原子视角 | Haas-Neill, L. | N/A | An all-atom view into the disordered interaction interface of the TRIM5α PRYSPRY domain and the HIV capsid | |
| 神经回路机制在支配特质与社会竞争中的作用 | Yan, H. | N/A | Neural Circuit Mechanisms Underlying Dominance Traits and Social Competition | |
| T细胞白血病中LMO2的降解会导致转录复合物伙伴的连带破坏以及LMO2依赖的细胞凋亡。 | Sereesongsaeng, N. | N/A | Degradation of LMO2 in T cell leukaemia causes collateral breakdown of transcription complex partners and LMO2-dependent apoptosis | |
| 使用生物发光共振能量转移技术检测7TM受体的基础性和配体依赖性Gi导向活性的关键策略 | Endzhievskaya, S. | N/A | Essential strategies for the detection of constitutive and ligand-dependent Gi-directed activity of 7TM receptors using bioluminescence resonance energy transfer | |
| 血管抑制素是由肾素-血管紧张素系统产生的。 | Nunez, F. F. | N/A | Vasoinhibin is Generated by the Renin-Angiotensin System | |
| 微血管保护和心肌细胞增生是先天性心脏病相关肺动脉高压中右心室适应性发育的基础。 | Smith, M. A. | N/A | Microvascular preservation and cardiomyocyte hyperplasia underlie adaptive right ventricular development in congenital heart disease-associated pulmonary arterial hypertension | |
| 基于先天适应性的早期运动训练的共享与独特适应性 | Sadler, D. G. | N/A | Shared and distinct adaptations to early-life exercise training based on inborn fitness | |
| 转录组与代谢的综合分析揭示了氧化还原稳态在羊草低光和盐复合胁迫中的功能作用 | Qu, M. | N/A | Integrative analysis of transcriptome and metabolism reveals functional roles of redox homeostasis in low light and salt combined stress in Leymus chinensis | |
| 利用INSIGHT技术在体内揭示扩散性胶质母细胞瘤细胞的信号网络 | Ahn, R. | N/A | Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT | |
| FTO（脂肪量和肥胖相关蛋白）缺乏会加重与年龄相关的抑郁样行为和认知功能障碍。 | Li, M. | N/A | FTO (fat-mass and obesity-associated protein) deficiency aggravates age-dependent depression-like behaviors and cognitive impairment | |
| 自上而下的注意力和阿尔茨海默病的病理影响在学习过程中对皮层的选择性，影响老年人的情景记忆。 | Sheng, J. | N/A | Top-down attention and Alzheimer's pathology impact cortical selectivity during learning,influencing episodic memory in older adults | |
| 活体中感觉轴突的口径在空间和时间上都有变化，并受细胞微环境的影响。 | Ching, K. | N/A | Caliber of sensory axons in vivo varies spatially and temporally and is influenced by the cellular microenvironment | |
| 抑制性连接的空间约束对尖峰网络中临界性动态发展的影响 | Kern, F. B. | N/A | Effects of Spatial Constraints of Inhibitory Connectivity on the Dynamical Development of Criticality in Spiking Networks | |
| 年龄相关的糖萼重塑驱动T细胞耗竭 | Zhang, H. | N/A | Age-related remodeling of the glycocalyx drives T cell exhaustion | |
| 一种人畜共患的H5N1血凝素结构揭示了一个被自身糖基占据的受体结合位点。 | Morano, N. C. | N/A | Structure of a zoonotic H5N1 hemagglutinin reveals a receptor-binding site occupied by an auto-glycan | |
| 利用冷冻电镜直接从免疫血清中发现功能性和表位特异性的单克隆抗体 | Ferguson, J. A. | N/A | Functional and epitope specific monoclonal antibody discovery directly from immune sera using cryoEM | |
| 转录组学图谱及伤口床周围的免疫微环境定义了小鼠指尖截肢后的再生与非再生结果 | Prabahar, A. | N/A | Transcriptomic Landscape and Immune Microenvironment AroundWound Bed Define Regenerative versus Non-regenerative Outcomesin Mouse Digit Amputation | |
| 揭示真食虫动物中微生物的多样性、传播途径及其人畜共患潜力 | Li, H. | N/A | Unveiling the diversity, transmission, and zoonotic potential of microbes in true insectivores | |
| 在混合小鼠多样性面板中，盐性和可卡因自我给药的遗传差异 | Khan, A. H. | N/A | Differing genetics of saline and cocaine self administration in the hybrid mouse diversity panel | |
| 利用3D生物打印的人类皮肤等效物识别强力HSV抗病毒药物 | Ellison, S. T. | N/A | Identification of potent HSV antivirals using 3D bioprinted human skin equivalents | |
| 载有神经递质的DNA纳米笼作为基于α-突触核蛋白的神经病变细胞和体内潜在治疗剂 | Vaswani, P. | N/A | Neurotransmitter loaded DNA nanocages as potential therapeutics for α-synuclein based neuropathies in cells and in vivo | |
| 磁力诱导磁小体链（MAGiC）：一种高性能且可导航的生物磁性粒子成像示踪剂 | Li, L. | N/A | Magnetically induced magnetosome chain (MAGiC):A biogenic magnetic-particle-imaging tracer with high performance and navigability | |
| 酵母知识图谱数据库，用于探索酿酒酵母和裂殖酵母 | Kumar, M. R. | N/A | Yeast Knowledge Graphs Database for Exploring Saccharomyces cerevisiae and Schizosaccharomyces pombe | |
| 超越细胞聚类和特征聚合：单细胞ATAC-seq数据中是否存在单细胞水平的信息？ | Kwok, A. W. C. | N/A | Going beyond cell clustering and feature aggregation: Is there single cell level information in single-cell ATAC-seq data? | |
| MEGA-FISH：面向大规模空间组学的多组学可扩展GPU加速FISH处理框架 | Ito, Y. | N/A | MEGA-FISH: Multi-omics Extensible GPU-Accelerated FISH Processing Framework for Huge-Scale Spatial Omics | |
| 四种皮肤类型中用于维生素D3合成的太阳紫外线B辐射 - 模型传播研究 | Pasricha, P. K. | N/A | Solar UVB Radiation for the Synthesis of Vitamin D3 in Four Skin Types - Model Propagation Studies | |
| 新见解：槲皮素金属离子螯合物对红斑减少的作用 | Bolano Alvarez, A. | N/A | New insight into erythema reduction induced by quercetin metal ions chelates | |
| HIV-1 Rev蛋白形成一个锌连接的二聚体。 | Khan, R. S. | N/A | HIV-1 Rev Protein Forms a Zinc-Linked Dimer | |
| 在单细胞水平上识别疾病特异性易损状态 | D'Antuono, M. | N/A | Identification of disease-specific vulnerability states at the single-cell level | |
| 一个针对真核生物线粒体细胞色素氧化酶亚基I基因（eKOI）的新型分类数据库：在宏条形码分析中提高群落水平的分类分辨率 | Gonzalez-Miguens, R. | N/A | A Novel Taxonomic Database for eukaryotic Mitochondrial Cytochrome Oxidase subunit I Gene (eKOI): Enhancing taxonomic resolution at community-level in metabarcoding analyses | |
| 从灾难到侵袭：通过森林结构和气象分析，将风灾树木损害与树皮甲虫爆发联系起来 | Torresani, M. | N/A | From calamity to infestation: linking windstorm tree damage to bark beetle outbreak through forest structure and meteorological analysis | |
| 跨越物种界限：环境DNA和基因分析揭示了美洲鳗鱼分布末端的杂交定居 | Jacobsen, M. W. | N/A | Bridging species boundaries: eDNA and genetic analysis reveal hybrid settlement at the very end of American eel distribution | |
| 成年人类下丘脑中单细胞分辨率的空间解析分子性别差异 | Mulvey, B. | N/A | Spatially-resolved molecular sex differences at single cell resolution in the adult human hypothalamus | |
| 通过整合静电纺膜和流动在肾小球共培养中生物制造过滤屏障 | mussoni, c. | N/A | Biofabrication of a filtration barrier by integrating electrospun membranes and flow in a glomerular co-culture | |
| 用于血友病A基因治疗的工程化凝血因子VIII，具有增强的分泌和凝血潜力 | Kashiwakura, Y. | N/A | Engineered coagulation factor VIII with enhanced secretion and coagulation potential for hemophilia A gene therapy | |
| 将人口聚类与基因组流行病学整合于PopPIPE | McHugh, M. P. | N/A | Integrated population clustering and genomic epidemiology with PopPIPE | |
| NCPepFold：通过多粒度表示的环化优化实现非规范环肽结构的准确预测 | Mao, Q. | N/A | NCPepFold: Accurate Prediction of Non-canonical Cyclic Peptide Structures via Cyclization Optimization with Multigranular Representation | |
| CCR1抑制增强了多发性骨髓瘤细胞对糖皮质激素治疗的敏感性。 | Luyckx, B. | N/A | CCR1 inhibition sensitizes multiple myeloma cells toglucocorticoid therapy | |
| 在癌症中追逐不存在的微小RNA | Orang, A. | N/A | Chasing non-existent microRNAs in cancer | |
| 骨保护素与纤维调节蛋白-1的相互作用对于纤维化肺组织中细胞外基质的沉积至关重要。 | Liu, Y. | N/A | Interaction of osteoprotegerin with fibulin-1 is essential for extracellular matrix deposition in fibrotic lung tissue | |
| ARID1A诱导的转录重编程重塑了黑色素瘤中对药物治疗的信号响应。 | Barker, C. G. | N/A | ARID1A-induced transcriptional reprogramming rewires signalling responses to drug treatment in melanoma | |
| 自我信念形成的时间相关波动 | Mayer, A. V. | N/A | Time-of-day related fluctuations of self-belief formation | |
| 动词-小品词结构的认知动态：一项眼动研究 | Kissane, H. | N/A | Cognitive Dynamics of Verb-Particle Constructions: An Eye-Tracking Study | |
| 肌肉、前庭和触觉刺激对梦境整合影响的比较研究 | Peters, E. | N/A | A Comparative Study of Muscular, Vestibular, and Haptic Stimulation on Dream Incorporation | |
| 小鼠海马CA1区锥体神经元的一个子集学习稀疏的突触输入模式。 | Shahul, A. K. | N/A | A subset of mouse hippocampus CA1 pyramidal neurons learns sparse synaptic input patterns. | |
| 在有或没有视觉刺激的情况下，视觉皮层各区域间的逐次交互作用 | Hidalgo, D. | N/A | Trial-by-trial inter-areal interactions in visual cortex in the presence or absence of visual stimulation | |
| 大脑反应的持续时间各不相同——建模策略与挑战 | Skukies, R. S. | N/A | Brain responses vary in duration - modelingstrategies and challenges | |
| 访问TIL衍生的CD8 T细胞在可切除的HBV-HCC患者中抑制肿瘤复发的能力 | Kah, J. | N/A | Accessing the specific capacity of TIL-derived CD8 T-cells to suppress tumor recurrence in resectable HBV-HCC patients | |
| Cited4a限制了斑马鱼心脏再生过程中心肌细胞的去分化和增殖 | Forman-Rubinsky, R. | N/A | Cited4a limits cardiomyocyte dedifferentiation and proliferation during zebrafish heart regeneration | |
| 扩散进化只能从气候变化中拯救有限数量的物种 | Kamal, P. | N/A | Dispersal evolution can only rescue a limited set of species from climate change | |
| ActinoMation：一种用于中通量链霉菌属机器人接合的文学编程方法 | Moeller, T. A. | N/A | ActinoMation: a literate programming approach for medium-throughput robotic conjugation of Streptomyces spp. | |
| 用于组成性高通量测序数据差异丰度检验的评分匹配方法 | Ostner, J. | N/A | Score matching for differential abundance testing of compositional high-throughput sequencing data | |
| NicheTrans：空间感知的多组学翻译 | Wang, Z. | N/A | NicheTrans: Spatial-aware Cross-omics Translation | |
| 通过活性噪声对细胞质粘度的超灵敏调控 | Zhao, Z. | N/A | Ultrasensitive tuning of cytoplasmic viscosity via active noise | |
| 白细胞介素-4诱导CD11c+小胶质细胞，从而改善小鼠的神经性疼痛 | Kohno, K. | N/A | Interleukin-4 induces CD11c+ microglia leading to amelioration of neuropathic pain in mice | |
| 高分辨率运动学方法用于量化肌营养不良斑马鱼幼体的运动障碍 | Widrick, J. J. | N/A | High resolution kinematic approach for quantifying impaired mobility of dystrophic zebrafish larvae | |
| 水稻叶片超疏水性的结构、遗传和适应性基础 | Hiraiwa, A. | N/A | Structural, genetic, and adaptive basis of superhydrophobicity in rice leaves | |
| 印度和坦桑尼亚大规模现场研究中的脑电数据质量 | Vianney, S. J.-M. | N/A | EEG data quality in large scale field studies in India and Tanzania | |
| 在人类和非人类灵长类动物中发现了与疫苗介导的结核病保护相关的体液相关性 | Kelkar, N. S. | N/A | Humoral correlate of vaccine-mediated protection from tuberculosis identified in humans and non-human primates | |
| 人类参考基因集中有超过2,500个编码基因的状态仍未确定。 | Maquedano, M. | N/A | More than 2,500 coding genes in the human reference gene set still have unsettled status | |
| 视网膜节细胞类型中与胆碱能视网膜波破坏相关的转录组变化 | Somaiya, R. D. | N/A | Transcriptomic changes in retinal ganglion cell types associated with the disruption of cholinergic retinal waves | |
| 为动态GABA编辑的磁共振波谱数据进行稳健的时间子采样建模：考虑射击间变异性 | Craven, A. R. | N/A | Modelling inter-shot variability for robust temporal sub-sampling of dynamic, GABA-edited MR spectroscopy data | |
| 大型效应生命史基因组区域与大西洋鲑的功能形态特征相关 | Aykanat, T. | N/A | Large effect life-history genomic regions are associated with functional morphological traits in Atlantic salmon | |
| 红藻UV性染色体的结构和进化特征 | Lipinska, A. P. | N/A | Structural and evolutionary features of red algal UV sex chromosomes | |
| 微小RNA的协同缺失揭示了啮齿动物基因调控的多层次重构 | Langschied, F. | N/A | Concerted loss of micro-RNAs uncovers multi-level restructuring of gene regulation in rodents | |
| 真菌毒素和草甘膦残留对欧洲黇鹿肠道微生物群及抗性组的影响 | Toth, A. G. | N/A | Impact of Mycotoxins and Glyphosate residue on the Gut Microbiome and Resistome of European Fallow Deer | |
| 鸽子对注视的跟随行为随着示范者数量的增加而增加。 | Delacoux, M. | N/A | Gaze Following in Pigeons Increases with the Number of Demonstrators | |
| BioMedGraphica：一个集成的平台，用于生物医学先验知识和组学信号图生成 | Zhang, H. | N/A | BioMedGraphica: An All-in-One Platform for Biomedical Prior Knowledge and Omic Signaling Graph Generation | |
| Gfa2bin通过将基因组图转换为泛基因组基因型，实现了基于图的GWAS（全基因组关联分析）。 | Vorbrugg, S. | N/A | Gfa2bin enables graph-based GWAS by converting genome graphs to pan-genomic genotypes | |
| 单分子生物剂量测定法 | Lamontagne, M. | N/A | Single-molecule biodosimetry | |
| 一种利用多物种基因组模型和基于原生质体的宏量并行报告基因分析来调控植物基因表达的可扩展方法 | Jevtic, S. | N/A | A scalable method for modulating plant gene expression using a multispecies genomic model and protoplast-based massively parallel reporter assay | |
| 单体/二聚体开关调节植物腺苷激酶的活性。 | Kopecny, D. J. | N/A | The monomer/dimer switch modulates the activity of plant adenosine kinase | |
| 《一百个神经网络与大脑观看视频：从对齐中汲取的教训》 | Sartzetaki, C. | N/A | One Hundred Neural Networks and Brains Watching Videos: Lessons from Alignment | |
| 使用滞后希尔伯特自相关法对神经节律性进行多尺度参数化 | Zhang, S. | N/A | Multi-scale parameterization of neural rhythmicity with lagged Hilbert autocoherence | |
| 使用滞后希尔伯特自相关对神经节律性进行多尺度参数化 | Zhang, S. | N/A | Multi-scale parameterization of neural rhythmicity with lagged Hilbert autocoherence | |
| deepBlastoid：一种基于深度学习的高通量分类器，用于使用明场图像对人类囊胚进行分类，并附带置信度评估 | Fan, Z. | N/A | deepBlastoid: A Deep Learning-Based High-Throughput Classifier for Human Blastoids Using Brightfield Images with Confidence Assessment | |
| 单细胞数据的系统发育动力学推断 | Dieselhorst, T. | N/A | Phylodynamic inference on single-cell data | |
| 酶调控的非热波动增强配体扩散和受体介导的内吞作用 | Nividha, | N/A | Enzyme-Regulated Non-Thermal Fluctuations Enhance Ligand Diffusion and Receptor-Mediated Endocytosis | |
| 心肌细胞STIM1下调通过失调线粒体超微结构和代谢信号，加剧心肌梗死后重塑 | Cacheux, M. | N/A | Cardiomyocyte STIM1 downregulation exacerbates post-Myocardial Infarction remodeling by dysregulating mitochondrial ultrastructure and metabolic signaling | |
| 鉴定非洲爪蟾胚胎组织中的类脑功能信息架构。 | Varley, T. | N/A | Identification of brain-like functional information architectures in embryonic tissue of Xenopus laevis. | |
| 朊病毒疾病的二价siRNA | Gentile, J. E. | N/A | Divalent siRNA for prion disease | |
| 使用交互式视觉语言系统对行走环境的自我中心感知 | Tan, H. | N/A | Egocentric perception of walking environments using an interactive vision-language system | |
| 与tau蛋白过度磷酸化相关的老年猕猴内嗅皮层钙信号失调。 | Bathla, S. | N/A | Dysregulated calcium signaling in the aged macaque entorhinal cortex associated with tau hyperphosphorylation. | |
| 古代沉积物中的DNA显示，在格兰德提顿国家公园，海狸连续居住了超过5000年。 | Baker, D. N. | N/A | Ancient sedimentary DNA shows more than 5000 years of continuous beaver occupancy in Grand Teton National Park | |
| 萨马科尾矿坝灾难发生六年后植物的招募：对物种丰富度和植物生长的影响 | Paz, A. A. | N/A | Plant recruitment six years after the Samarcos tailings-dam disaster: Impacts on species richness and plant growth | |
| 微粒局部递送生长因子调控体外鸡胚骨模型中依赖生长因子的成骨和成软骨基因表达。 | Rashidi, H. | N/A | Localized Delivery of Growth Factors from Microparticles Modulate Osteogenic and Chondrogenic Gene Expression in Growth Factor-dependent Manner in an ex vivo Chick Embryonic Bone Model. | |
| 定义SARS-CoV-2刺突糖蛋白受体结合基序中高度保守的B细胞表位 | Malladi, S. K. | N/A | Defining a highly conserved B cell epitope in the receptor binding motif of SARS-CoV-2 spike glycoprotein | |
| 罗氏菌属新种Rhodococcus parequi sp. nov.，是从马场土壤中分离得到的一种新种，与病原菌Rhodococcus equi密切相关。 | Vazquez-Boland, J. A. | N/A | Rhodococcus parequi sp. nov., a new species isolated from equine farm soil closely related to the pathogen Rhodococcus equi. | |
| 人乳微生物组宏基因组检测方法的优化 | Zhang, Q. | N/A | Optimization of metagenomic detection method for human breast milk microbiome | |
| 细菌的Site 2蛋白酶通过靶向噬菌体裂解蛋白，在抵抗RNA噬菌体中发挥作用。 | Bae, H.-W. | N/A | A bacterial site 2 protease contributes to RNA phage resistance by targeting phage lysis protein | |
| 冷冻电镜解析了古菌双链DNA病毒HFTV1从头部到尾部的结构。 | Zhang, D. X. | N/A | Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail | |
| mRNA从核糖体中释放出来并配对作为单向正向旁路跳跃的驱动力的证据：其停止允许反向扫描。 | Atkins, J. | N/A | Evidence for the pairing of mRNA exiting ribosomes acting as a Driver of unidirectional forward bypassing: Its cessation permits Backwards scanning | |
| 章鱼中的Z染色体剂量补偿与一种雄性特异性长链非编码RNA | Papanicolaou, N. | N/A | Z-chromosome dosage compensation and a male-specific lncRNA in octopus | |
| 结构更多，精度更少：ESM3的结合预测悖论 | Loux, T. | N/A | More Structures, Less Accuracy: ESM3's Binding Prediction Paradox | |
| XPG-DNA损伤结合动态的调控：由切刻前和切刻后核酸切除修复因子和EXO1共同参与 | Muniesa-Vargas, A. | N/A | Regulation of XPG-DNA damage binding dynamics by pre- and post-incision nucleotide excision repair factors and EXO1 | |
| XRN1 提供游离核苷酸，以支持阿尔法病毒的复制过程。 | Ruscica, V. | N/A | XRN1 supplies free nucleotides to feed alphavirus replication | |
| DDI-GPT：利用知识图谱增强的大型语言模型进行药物-药物相互作用的解释性预测 | Xu, C. | N/A | DDI-GPT: Explainable Prediction of Drug-Drug Interactions using Large Language Models enhanced with Knowledge Graphs | |
| SARS-CoV-2刺突蛋白进化的综合分析：表位分类与免疫逃逸预测 | Teruel, N. F. B. | N/A | Comprehensive Analysis of SARS-CoV-2 Spike Evolution: Epitope Classification and Immune Escape Prediction | |
| DNA复制介导的双组分调控系统激活作为Burkholderia thailandensis的一种对冲策略 | Lowrey, L. C. | N/A | DNA duplication-mediated activation of a two-component regulatory system serves as a bet-hedging strategy for Burkholderia thailandensis | |
| 爱沙尼亚人群肠道古菌收集 | Pantiukh, K. | N/A | Human gut archaea collection from Estonian population | |
| 群体感应调节的小RNA Lrs1参与了铜绿假单胞菌对低铁环境的适应。 | Panagiotopoulou, D. | N/A | The Quorum Sensing regulated sRNA Lrs1 is involved in the adaptation to low iron in Pseudomonas aeruginosa | |
| PqsE作为铜绿假单胞菌特异性LuxR型受体调节器的演变：来自假单菌属和伯克霍尔德菌属的启示 | Paczkowski, J. E. | N/A | Evolution of PqsE as a Pseudomonas aeruginosa-specific regulator of LuxR-type receptors: insights from Pseudomonas and Burkholderia | |
| 无肠海生蠕虫硫酸盐还原共生体的基因组和蛋白质组特征 | D'Angelo, G. | N/A | Genomic and proteomic characterization of sulfate-reducing symbionts of gutless marine annelids | |
| 噪声暴露前后大鼠尿液蛋白质组的变化 | Yang, M. | N/A | Changes in urinary proteome of rats before and after noise exposure | |
| 转录组分析揭示了新品种豚鼠肌肉肥大的MSTN突变及机制 | Carmen, S. | N/A | Transcriptomic Analysis Reveals MSTN Mutations and Mechanisms of Muscle Hypertrophy in a New Guinea Pig Breed | |
| 转录因子与NIPBL/MAU2形成三元复合物，以在增强子上定位cohesin。 | Fettweis, G. | N/A | Transcription factors form a ternary complex with NIPBL/MAU2 to localize cohesin at enhancers | |
| 通过单细胞RNA测序在三刺鱼中识别的不同细胞类型的进化速率存在差异。 | Rodgers, M. L. | N/A | Rates of evolution differ between cell types identified by single-cell RNAseq in threespine stickleback | |
| 非典型结构与功能：来自Additional Sex Combs-like蛋白的PHD结构域 | Reddington, C. J. | N/A | Unconventional structure and function of PHD domains from Additional Sex Combs-like proteins | |
| CECR2溴结构域展现出对乙酰化组蛋白与非组蛋白配体不同的结合模式。 | Phillips, M. | N/A | The CECR2 bromodomain displays distinct binding modes to select for acetylated histone proteins versus non-histone ligands. | |
| 基于动力学和结构的比较：沉默型鞭毛蛋白与刺激型鞭毛蛋白与TLR5的相互作用 | Bell, M. E. W. | N/A | Kinetic and structure-based comparisons of silent and stimulatory flagellin interactions with TLR5 | |
| 黏蛋白在流感病毒抑制中的结构决定因素：唾液酸化糖类与分子大小的协同作用 | Butnarasu, C. | N/A | Structural Determinants of Mucins in Influenza Virus Inhibition: The Synergistic Role of Sialylated Glycans and Molecular Size | |
| 通过单电子氧化实现手性选择性光酶催化C(sp3)-H功能化 | Zhu, J. | N/A | Enantioselective photoenzymatic C(sp3)-H functionalization via single-electron oxidation of carbanions | |
| 工程酵母中提取的必需固醇可防止蜜蜂群体数量下降 | Moore, E. V. | N/A | Essential sterols from engineered yeast prevent honeybee colony population decline | |
| 实证研究表明，转移性喂养能提高地面筑巢鸟类的生产力。 | Bamber, J. A. | N/A | Empirical evidence that diversionary feeding increases productivity in ground-nesting birds. | |
| 在人工环境中通过调整环境条件实现造礁珊瑚的“非季节性”产卵 | Koukoumaftsis, L. P. | N/A | Controlled 'out-of-season' spawning of reef-forming corals in aquaria using offset environmental profiles | |
| 极度濒危的阿拉伯剑羚（Gazella arabica acacia）饮食策略的保育意义 | Lavie, N. | N/A | Conservation implications of dietary strategies in the critically endangered Acacia gazelle (Gazella arabica acacia) | |
| 基于凝集素的天然糖RNA的简单快速检测 | Li, Y. | N/A | Simple and rapid lectin-based detection of native glycoRNAs | |
| 鸣禽在东喜马拉雅混种鸟群中处于更核心的地位。 | Gupta, S. | N/A | Vocal species are more central in Eastern Himalayan Mixed-Species bird flocks | |
| 共生效应、产卵不同步以及混合繁殖模式在常见的大规模产卵珊瑚中 | Ricardo, G. F. | N/A | Allee effects, spawning asynchrony, and mixed reproductive modes in a common mass spawning coral | |
| # BioRxiv 2024-12-08 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 个体间在皮层组织的感觉运动-关联轴上的差异具有独特的遗传基础 | Bignardi, G. | N/A | Distinct genetic underpinnings of inter-individual differences in the sensorimotor-association axis of cortical organisation | |
| RNA结合蛋白IMP1/ZBP1驱动Actb mRNA在微胶质细胞外周突起中的定位和局部翻译，并介导形态变化、运动性和吞噬作用以响应炎症 | Imaz-Iruretagoyena, J. | N/A | RNA binding protein IMP1/ZBP1 drives Actb mRNA localization and local translation in microglial peripheral processes and mediates morphological changes, motility and phagocytosis in response to inflammation | |
| 保守的3'茎环结构使我们能够在宏基因组中全面分析细菌转录终止，无论是否依赖Rho因子 | Jin, Y. | N/A | Conserved 3' Stem-Loop Structures Enable Comprehensive Analysis of Bacterial Transcription Termination in Metagenomes, Regardless of Rho Factor Dependency | |
| 通过快速突触变化实现的简单句法规则 | Sun, L. | N/A | Simple syntactic rules through rapid synaptic changes | |
| miRTarDS：利用Sentence-BERT从预测数据库中高精度提炼蛋白质水平的微RNA目标相互作用 | Chen, B. | N/A | miRTarDS: High-Accuracy Refining Protein-level MicroRNA Target Interactions from Prediction Databases Using Sentence-BERT | |
| 微囊藻中标记基因及细胞内无定形碳酸钙生物矿化候选基因表达的昼夜变化 | Bruley, A. | N/A | Diel changes in the expression of a marker gene and candidate genes for intracellular amorphous CaCO3 biomineralization in Microcystis | |
| 值班爸爸：斑胸草雀首次孵卵记录 | Scheiber, I. B. R. | N/A | Dads on duty: First account of nest sitting in barnacle ganders | |
| 谱系限制的机制基础 | Wu, B. | N/A | Mechanistic basis of lineage restriction | |
| 每月对大型藻类的调查显示，城市潮间带区域存在着一个多样且动态的生物群落。 | Schenk, S. | N/A | Monthly macroalgal surveys reveal a diverse and dynamic community in an urban intertidal zone | |
| 淀粉样前体蛋白（Amyloid Beta Precursor Protein）在短命的蓝绿光鳉鱼（Nothobranchius furzeri）中促进了脑衰老和学习能力的下降。 | de Bakker, D. E. M. | N/A | Amyloid Beta Precursor Protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri) | |
| 对蝾螈Y染色体更替的鉴定未能支持Triturus平衡致死系统起源于性染色体 | France, J. M. | N/A | Identification of Y-chromosome turnover in newts fails to support a sex chromosome origin for the Triturus balanced lethal system | |
| 在胚胎关键期，线粒体活性氧和HIF1-α信号的保守作用指导了后续神经系统发育。 | Sobrid-Camean, D. | N/A | Conserved mitochondrial reactive oxygen species and HIF1-alpha signalling during an embryonic critical period directs subsequent nervous system development | |
| 内耳神经元脱层的时间决定了它们的地形和目标神经支配 | Saini, S. S. J. S. | N/A | Timing of delamination of inner ear neurons specifies their topography and target innervation | |
| 细菌计数时连续稀释过程中样本体积传递与传递次数之间的权衡 | Jain, M. | N/A | Trade-off between sample volume passaged and number of passages involved during serial dilution for bacterial enumeration | |
| 人巨细胞病毒全病毒蛋白质组学揭示gpUL141是一种病毒颗粒成分，通过调节包膜糖蛋白组成以抵御体液免疫 | Bentley, K. | N/A | Whole Virion Proteomics of HCMV Reveals that gpUL141 is a Virion Component that Regulates Envelope Glycoprotein Composition to Protect Against Humoral Immunity | |
| 葡萄糖感应ChREBP蛋白在糖尿病视网膜病变发病机制中的作用 | Starr, C. R. | N/A | Glucose-Sensing ChREBP Protein in the Pathogenesis of Diabetic Retinopathy | |
| 自愿行动能增强感官预测，并促进对相关感官刺激的神经处理。 | Ody, E. | N/A | Voluntary action sharpens sensory prediction and facilitates neural processing of contingent sensory stimuli | |
| 个性预测在新栖息地中的扩散和定居——一项中尺度实验 | Gismann, J. | N/A | Personality predicts dispersal and settlement in a novel habitat - a mesocosm experiment | |
| 北极星：人类群体中扩展单倍型纯合性推断的祖先和衍生多态等位基因的极化。 | Lisi, A. | N/A | Polaris: Polarization of ancestral and derived polymorphic alleles for inferences of extended haplotype homozygosity in human populations. | |
| 腹侧被盖区GABA神经元整合正负效价 | Stelzner, M. E. | N/A | Ventral tegmental area GABA neurons integrate positive and negative valence | |
| GABA能杏仁核神经元中的HCN1通道支撑着偏向雄性的攻击行为 | Li, K. | N/A | HCN1 channels in GABAergic amygdalar neurons underpin male-biased aggressive behaviors | |
| 通过磁共振成像组织学表征的黑猩猩大脑寿命轨迹 | Lipp, I. | N/A | Lifespan trajectory of chimpanzee brains characterized by magnetic resonance imaging histology | |
| Pcdh15在内耳毛细胞内在极性发育中的作用 | Kaushik, R. | N/A | Role Of Pcdh15 In The Development Of Intrinsic Polarity Of Inner Ear Hair Cells | |
| 空间单细胞细胞器组学揭示了营养依赖的肝细胞异质性，并预测了体内的病理生理状态 | Hillsley, A. | N/A | Spatial single-cell Organellomics reveals nutrient dependent hepatocyteheterogeneity and predicts pathophysiological status in vivo | |
| 单细胞分析揭示了B细胞发育的多方面特征，以及与年龄相关的B细胞亚群 | Yang, X. | N/A | Single-cell analysis reveals multi-faceted features of B cell development together with age-associated B cell subpopulations | |
| 高尔基体中谷胱甘肽氧化还原状态的表征 | Miro-Vinyals, C. | N/A | Characterization of the Glutathione Redox State in the Golgi Apparatus | |
| 储存操作的钙离子进入参与了肺血管内皮细胞中的内皮间质转化 | Babicheva, A. | N/A | Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells | |
| FNBP4介导的非中心体形成蛋白FMN1在肌动蛋白细胞骨架动态调控中的机制性见解 | Das, S. | N/A | Mechanistic Insights into FNBP4-Mediated Regulation of non-diaphanous Formin FMN1 in Actin Cytoskeleton Dynamics | |
| MuSpAn：一个多尺度空间分析工具箱 | Bull, J. A. | N/A | MuSpAn: A Toolbox for Multiscale Spatial Analysis | |
| SubCell: 用于显微镜的视觉基础模型捕捉单细胞生物学 | Gupta, A. | N/A | SubCell: Vision foundation models for microscopycapture single-cell biology | |
| 从卵母细胞中分离和操控减数分裂纺锤体揭示了在不对称分裂过程中由牵引力调控的迁移 | Liu, N. | N/A | Isolation and manipulation of meiotic spindles from mouse oocytes reveals migration regulated by pulling force during asymmetric division | |
| 染色质压缩遵循幂律缩放规律，从间期到有丝分裂期间，其与细胞大小成比例变化。 | Stockinger, P. | N/A | Chromatin Compaction Follows a Power Law Scaling with Cell Size from Interphase Through Mitosis | |
| 超分辨成像揭示了CD81微区在调节Jurkat T细胞微绒毛膜信号传导中的空间组织 | Ramseier, N. | N/A | Superresolution Imaging Reveals the Spatial Organization of CD81 Microdomains in Regulating Membrane Signaling on Jurkat T Cell Microvilli | |
| FAK活性通过VEGFR2-Cbl-NF-κB信号通路加剧了扰流介导的动脉粥样硬化。 | Lim, S. | N/A | FAK activity exacerbates disturbed flow-mediated atherosclerosis via VEGFR2-Cbl-NF-κB signaling. | |
| 用于面部修复、再生和抗衰老的外泌体：不同商业产品之间的比较 | Salvaggio, A. | N/A | Exosomes for facial repair, regeneration and rejuvenation: comparison between different commercial products | |
| 间充质干细胞/基质细胞向CD45+巨噬细胞样细胞的分化：拓展对MSC可塑性的认识 | Rusch, R. M. | N/A | Differentiation of Mesenchymal Stem/ Stromal Cells into CD45+ Macrophage-like Cells: Expanding Insights into MSC Plasticity | |
| 肌修复过程中肌营养不良蛋白表达的时空分析 | Hildyard, J. C. W. | N/A | Spatiotemporal analysis of dystrophin expression during muscle repair | |
| 普利帕斯汀是枯草芽孢杆菌在对抗镰刀菌属时共享的一种有益物质。 | Stannius, R. O. | N/A | Plipastatin is a shared good by Bacillus subtilis during combating Fusarium spp. | |
| 细胞内RNA环状结构水平升高会抑制抗病毒反应。 | Duan, C. | N/A | Elevated levels of intracellular RNA lariats suppress the antiviral response | |
| 去组蛋白修饰的Cas12a增强了单细胞CRISPR筛选 | Snetkova, V. | N/A | Degron-modified Cas12a enhances single-cell CRISPR screening | |
| 人类遗传变异揭示FCRL3是淋巴细胞的鼠疫耶尔森菌受体 | Keener, R. | N/A | Human genetic variation reveals FCRL3 is a lymphocyte receptor for Yersinia pestis | |
| Leucine Rich Repeat Kinase 2的Ras of Complex Proteins/GTPase结构域中的功能丧失性编码变异 | Butterfield, S. | N/A | Loss-of-function coding variants in the Ras of Complex Proteins/GTPase domain of Leucine Rich Repeat Kinase 2 | |
| 利用DMS MaP-Seq技术概念化核糖体mRNA解旋 | Kellenberger, P. | N/A | Conceptualizing Ribosomal mRNA Unwinding Utilizing DMS MaP-Seq | |
| 细胞修饰tRNALys3的氨酰化的人类赖氨酰-tRNA合成酶的结构基础 | Devarkar, S. C. | N/A | Structural basis for aminoacylation of cellular modified tRNALys3 by human lysyl-tRNA synthetase | |
| 评估HGNC中人类非编码RNA命名的稳健性 | Prasetyo, N. K. | N/A | Assessing the robustness of human ncRNA notation at HGNC | |
| 基于HSV-1基因组维持的HEK293细胞开发EASY-HSV（高效且简单的高产单纯疱疹病毒载体）系统 | Maeda, F. | N/A | Development of the EASY-HSV (Efficient And Simple high-Yield Herpes Simplex virus Vector) system based on HSV-1 genome-maintaining HEK293 cells | |
| 脂质纳米颗粒递送mRNA逆转溶酶体酸性脂肪酶缺乏症的病理发生于临床前模型中 | Zadory, M. | N/A | Lipid-based nanoparticles deliver mRNA to reverse the pathogenesis of lysosomal acid lipase deficiency in a preclinical model | |
| OMAnnotator：一种构建注释共识基因组序列的新方法 | Bates, S. | N/A | OMAnnotator: a novel approach to building an annotated consensus genome sequence | |
| ProkBERT PhaStyle：利用预训练基因组语言模型进行准确的噬菌体生活方式预测 | Juhasz, J. | N/A | ProkBERT PhaStyle: Accurate Phage Lifestyle Prediction with Pretrained Genomic Language Models | |
| 体外调节基于肌动蛋白的活性组装的收缩性和变形模式：从二维活性网络到液晶液滴 | Stam, S. | N/A | Tuning the contractility and deformation modes of active actin-based assemblies in vitro: from 2D active networks to liquid crystal drops | |
| CCR7和细胞粘附分子在鸡胚发育中对B细胞迁移至法氏囊的调控 | Brunner, M. | N/A | Regulation of B cell migration to the Bursa of Fabricius by CCR7 and cell adhesion molecules in chicken embryonic development | |
| 源自肉桂皮提取物的纳米杀菌剂：植物化学成分分析及其对水稻细菌性穗枯病的抗菌功效 | Alsutan, Q. M. | N/A | Nanobactericides Derived from Cinnamon Bark Extract: Phytochemical Profiling and Antibacterial Efficacy Against Bacterial Panicle Blight in Rice | |
| 根际土壤微生物类群的活性可以预测根系定殖的成功与否。 | Harris, J. E. | N/A | The activity of soil microbial taxa in the rhizosphere predicts the success of root colonization | |
| 人诱导多能干细胞衍生的肌肉细胞作为研究EDMD1发病机制的新模型。 | Lisowska, M. | N/A | Human iPSCs-derived muscle cells as a new model for investigation of EDMD1 pathogenesis. | |
| 一码多用：用于修复热点外显子剪接突变的反义寡核苷酸 | Duan, C. | N/A | One-Size-Fits-Many: Antisense oligonucleotides for rescuing splicing mutations in hotspot exons | |
| 透明质酸与新兴组织力学协同调控指尖再生 | Mui, B. W. H. | N/A | Hyaluronic Acid and Emergent Tissue Mechanics Orchestrate Digit Tip Regeneration | |
| 没有证据表明蝴蝶的蛋白质组组成与其实际的温度极限和饮食生态位宽度有关。 | Caron, F. | N/A | No evidence that proteome composition is associated with realised thermal limit and dietary niche breadth in butterflies | |
| 亚致死剂量的农药暴露会降低有益传粉者的交配率并扰乱其化学信号传递。 | Derstine, N. | N/A | Sublethal pesticide exposure decreases mating and disrupts chemical signaling in a beneficial pollinator | |
| 减数分裂性染色体失活：果蝇属中的保守性 | Avelino, C. C. | N/A | Meiotic Sex Chromosome Inactivation: conservation across the Drosophila genus | |
| 发现5mC特异性脱氨酶及其在碱基分辨率下超灵敏直接测序甲基化位点的应用。 | Yang, W. | N/A | The discovery of 5mC-selective deaminases and their application to ultra-sensitive direct sequencing of methylated sites at base resolution. | |
| SpatioMark：量化空间邻近性对细胞表型的影响 | Iyengar, S. S. | N/A | SpatioMark: Quantifying the impact of spatial proximity on cell phenotype | |
| 建模并预测单细胞多基因扰动响应：scLAMBDA | Wang, G. | N/A | Modeling and predicting single-cell multi-gene perturbation responses with scLAMBDA | |
| CASSIA能够在单细胞RNA测序数据中进行稳健、自动的细胞注释。 | Xie, E. | N/A | CASSIA allows for robust, automated cell annotation in single-cell RNA-sequencing data | |
| 果蝇连接组中的并行与汇聚多感官级联 | Betzel, R. F. | N/A | Parallel and converging multisensory cascades in the Drosophila connectome | |
| 利用FoxP2区分鸣禽发声学习中的直接和间接基底神经节通路 | Jagannathan, A. | N/A | Using FoxP2 to Distinguish Direct and Indirect Basal Ganglia Pathways for Vocal Learning in Songbirds | |
| # BioRxiv 2024-12-07 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 利用深度领域自适应匹配从体内尖峰序列中重建电路连接性 | Sheng, K. | N/A | Reconstructing Circuit Connectivity from in vivo Spike Trains Using Deep Domain-Adaptive Matching | |
| 典型想象者和无想象症者中的视觉心理意象：一项毫米级7-T fMRI研究 | Liu, J. | N/A | Visual mental imagery in typical imagers and in aphantasia: A millimeter-scale 7-T fMRI study | |
| 音高并非螺旋：探究音乐音高在不同任务和经验中的结构 | Marjieh, R. | N/A | Pitch is Not a Helix: Probing the Structure of Musical Pitch Across Tasks and Experience | |
| 用于研究果蝇联想学习的驱动线 | Shuai, Y. | N/A | Driver lines for studying associative learning in Drosophila | |
| BRAF抑制剂二聚体选择性和结合协同作用的机制 | Clayton, J. | N/A | Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors | |
| 通过个性化碱基编辑在iPSC衍生的神经元中建模和校正蛋白质构象疾病 | Konishi, C. T. | N/A | Modeling and Correction of Protein Conformational Disease in iPSC-derived Neurons through Personalized Base Editing | |
| 通过共表达AsCas12a超变体、T7 RNA聚合酶和胞嘧啶碱基编辑器，改进了利什曼原虫的基础编辑和功能筛选。 | May, N. H. | N/A | Improved base editing and functional screening in Leishmania via co-expression of the AsCas12a ultra variant, a T7 RNA Polymerase, and a cytosine base editor | |
| 一个反馈驱动的脑类器官平台能够实现自动维护和高分辨率神经活动监测。 | Voitiuk, K. | N/A | A feedback-driven brain organoid platform enables automated maintenance and high-resolution neural activity monitoring | |
| 细胞内口袋构象通过μ阿片受体决定信号传导 | Cooper, D. A. | N/A | Intracellular pocket conformations determine signaling through the μ opioid receptor | |
| 果蝇腿部本体感受和外感受神经回路的差异 | Lee, S.-Y. J. | N/A | Divergent neural circuits for proprioceptive and exteroceptive sensing of the Drosophila leg | |
| 细菌双链DNA病毒基因组图谱的探索揭示了在广泛镶嵌性中存在ANI差距 | Ndovie, W. | N/A | Exploration of the genetic landscape of bacterial dsDNA viruses reveals an ANI gap amidst extensive mosaicism | |
| SAUSI：一种用于测量社交回避与动机的综合测验 | Grammer, J. | N/A | SAUSI: an integrative assay for measuring social aversion and motivation | |
| 降低腹内侧下丘脑（VMH）中神经元一氧化氮合酶（nNOS）的表达会增加雌性小鼠的体重和血糖水平，同时减少其体力活动。 | Hirschberg, P. R. | N/A | Reducing neuronal nitric oxide synthase (nNOS) expression in the ventromedial hypothalamus (VMH) increases body weight and blood glucose levels while decreasing physical activity in female mice. | |
| 可解释的蛋白质-DNA相互作用通过结构-序列优化捕捉 | Zhang, Y. | N/A | Interpretable Protein-DNA Interactions Captured by Structure-Sequence Optimization | |
| 竞争效应调节微小RNA池的组成 | Raak, S. B. | N/A | Competition effects regulating the composition of the microRNA pool | |
| 解读情绪状态下内侧前额叶皮层下行通路中的隐藏变异性 | Lai, C.-H. | N/A | Decoding the hidden variabilities in mPFC descending pathways across emotional states | |
| 海南岛非结核分枝杆菌的分布、流行及耐药性 | Xu, X. | N/A | Distribution, Prevalence, and Antibiotic Resistance of Non-Tuberculous Mycobacteria on Hainan Island | |
| 支原体滑动运动的F1样ATP酶的二聚体组装 | Toyonaga, T. | N/A | Dimeric assembly of F1-like ATPase for the gliding motility of Mycoplasma | |
| 消费者体型和栖息地偏好对资源分布的空间指纹 | Little, C. J. | N/A | Spatial fingerprint of consumer body size and habitat preference on resource distribution | |
| 朝着昆虫相机陷阱图像的边缘处理方向发展 | Bjerge, K. | N/A | Towards edge processing of images from insect camera traps | |
| 平行HIV-1适应性景观塑造了人类和猕猴中病毒动力学，这些宿主能够产生广谱中和抗体。 | Shimagaki, K. S. | N/A | Parallel HIV-1 fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies. | |
| 躯体感觉知觉的兴奋性调节并不依赖于前馈神经元群体的放电。 | Stephani, T. | N/A | Excitability modulations of somatosensory perception do not depend on feedforward neuronal population spikes | |
| 条件序列-结构整合：一种用于精准抗体工程和亲和力优化的创新方法 | Jamialahmadi, B. | N/A | Conditional Sequence-Structure Integration: A Novel Approach for Precision Antibody Engineering and Affinity Optimization | |
| 非周期性和振荡系统构成了人类领域一般认知的基础 | Lu, R. | N/A | Aperiodic and oscillatory systems underpinning human domain-general cognition | |
| PeakClimber：一种用于使用指数高斯函数精确量化复杂多分析物HPLC色谱图的软件工具 | Derrick, J. | N/A | PeakClimber: A software tool for the accurate quantification of complex multianalyte HPLC chromatograms using the exponential Gaussian function | |
| SOI：利用直系同源指数进行同线性基因组的鲁棒鉴定及其在进化基因组学中的广泛应用 | Zhang, R.-G. | N/A | SOI: Robust identification of orthologous synteny with the Orthology Index and broad applications in evolutionary genomics | |
| 双光子NAD(P)H-FLIM显示，与宿主巨噬细胞在接触青蒿素衍生物后不同，猪蛔虫幼虫的能量代谢未受影响。 | Musimbi, Z. D. | N/A | Two-Photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure | |
| 具身视角：角回和楔前叶在自然事件记忆中解码自我身份 | Iriye, H. | N/A | An embodied perspective: angular gyrus and precuneus decode selfhood in memories of naturalistic events | |
| 血清素类迷幻药DOI会损害听觉皮层的异常检测能力 | Horrocks, M. | N/A | The serotonergic psychedelic DOI impairs deviance detection in the auditory cortex | |
| BindCraft：功能性蛋白质结合剂的一步设计 | Pacesa, M. | N/A | BindCraft: one-shot design of functional protein binders | |
| 中性粒细胞表现出不同的迁移表型，这些表型受跨内皮迁移的调控。 | Schwartz, A. B. | N/A | Neutrophils exhibit distinct migration phenotypes that are regulated by transendothelial migration | |
| 伏隔核D2表达神经元：通过节律性光遗传刺激平衡奖励与舔舐中断 | Requejo-Mendoza, N. | N/A | Nucleus accumbens D2-expressing neurons: Balancing reward and licking disruption through rhythmic optogenetic stimulation | |
| 高吞吐量蛋白质组学和磷酸蛋白质组学分析的福尔马林固定石蜡包埋组织 | Haines, M. | N/A | High-throughput proteomic and phosphoproteomic analysis of formalin-fixed paraffin-embedded tissue | |
| 寄生虫、宿主、猎物和环境之间的LINE-RTE逆转录转座子的水平转移。 | Brann, T. | N/A | Horizontal transfer of a LINE-RTE retrotransposon among parasite, host, prey and environment. | |
| 编程群体组成和多细胞形态的合成比例计算 | An, B. | N/A | Synthetic ratio computation for programming population composition and multicellular morphology | |
| 转录因子GATA1识别RNA的独特机制 | Ugay, D. A. | N/A | A distinct mechanism of RNA recognition by the transcription factor GATA1 | |
| 大豆（Glycine max. (L.) Merrill）品系表型形态特征及遗传多样性评估，以促进育种进展 | Saha, M. | N/A | Pheno-Morphological Characterization and Genetic Diversity Assessment of Grain and Vegetable Soybean (Glycine max. (L.) Merrill) Lines for Breeding Advancements | |
| 单倍二倍体加速了昆虫线粒体基因组的进化 | Pakrashi, A. | N/A | HAPLODIPLOIDY ACCELERATES MITOGENOME EVOLUTION IN INSECTS | |
| RpiBeh：一种多用途的开源解决方案，用于实时追踪和基于行为驱动的啮齿动物神经行为学闭环干预 | Sun, Y. | N/A | RpiBeh: a multi-purpose open-source solution for real-time tracking and behavior-driven closed-loop interventions in rodent neuroethology | |
| 冷冻电镜显示，源自心脏IGLV6的AL纤维可以具有多态性。 | Bassett, P. T. | N/A | Cryo-EM reveals that cardiac IGLV6-derived AL fibrils can be polymorphic | |
| 科学出版物中定量聚合酶链反应（qPCR）方法的报告质量 | Drude, N. I. | N/A | Reporting quality of quantitative polymerase chain reaction (qPCR) methods in scientific publications | |
| 你可以做到！利用已发表的关于水螅口部张开的本科生研究来训练本科生 | Hackler, S. | N/A | You can do it! Using published undergraduate research on Hydra mouth opening to train undergraduates | |
| Ozboneviz：澳大利亚在FAIR 3D影像和扩展生物多样性收藏方面的先例 | Weisbecker, V. | N/A | Ozboneviz: An Australian Precedent in FAIR 3D Imagery and Extended Biodiversity Collections | |
| 符号和非符号数字在数字线二等分任务中对中心识别的影响不同 | Porru, A. | N/A | Symbolic and Non-Symbolic numbers differently affect centre identification in a number-line bisection task | |
| 发作间期抑制性网络的崩溃允许癫痫发作扩散 | Makhoul, G. S. P. | N/A | Collapse of Interictal Suppressive Networks Permits Seizure Spread | |
| 控制感能缓解压力 | Fielder, J. C. | N/A | Sense of control buffers against stress | |
| 执行功能与更新预测表征之间的相互作用 | Pedraza, F. | N/A | The interplay between executive functions and updating predictive representations | |
| 前扣带皮层损伤会破坏人类处理奖励的电生理特征 | Oerlemans, J. | N/A | Lesions of anterior cingulate cortex disrupt an electrophysiological signature of reward processing in humans | |
| 外周免疫细胞对刺激的反应将帕金森病从前驱期到临床期的进展进行了分层 | Mark, J. R. | N/A | Peripheral immune cell response to stimulation stratifies Parkinson's disease progression from prodromal to clinical stages | |
| 模拟驾驶环境中器乐对双任务干扰的影响 | Khadiv, E. | N/A | The Impact of Instrumental Music on Dual-task Interference in a Simulated Driving Environment | |
| ForestForward：可视化和访问过去五十年综合世界森林数据 | Tejada-Gutierrez, E. L. | N/A | ForestForward: visualizing and accessing integrated world forest data from the last fifty years | |
| 接受个体化新抗原导向疫苗治疗的转移性癌症患者全面纵向ctDNA监测 | Schenk, D. | N/A | Comprehensive Longitudinal ctDNA Monitoring in Metastatic Cancer Patients Treated with an Individualized Neoantigen-directed Vaccine | |
| PISA：多功能3D单分子光片显微镜 | Taniguchi, Y. | N/A | PISA: versatile microscope for 3D single molecule light sheet imaging | |
| 积雪草组织培养衍生的胞外囊泡：多角度应用于护肤领域 | Chang, T.-M. | N/A | Centella asiatica Tissue Culture-Derived Extracellular Vesicles: A Multifaceted Approach to Skincare Applications | |
| 比较功能性和结构性神经影像数据中的个体内部和个体间相关脑连接性 | Di, X. | N/A | Comparing Intra- and Inter-individual Correlational Brain Connectivity from Functional and Structural Neuroimaging Data | |
| 周围传入纤维对脊髓感觉输入的调节。寻找中继站 | Slawinska, U. | N/A | Modulation of sensory input to the spinal cord by peripheral afferent fibres. Searching for relays | |
| 通过台式质谱仪进行多模态脂质-蛋白质-组织学成像，探索阿尔茨海默病小鼠中的Aβ斑块微环境 | Mueller, E. | N/A | Exploring the Abeta Plaque Microenvironment in Alzheimer's Disease Mice by Multimodal Lipid-Protein-Histology Imaging on a Benchtop Mass Spectrometer | |
| 评估空间化声学场景中变化检测的行为和神经相关性 | Poole, K. C. | N/A | Assessing Behavioral and Neural Correlates of Change Detection in Spatialized Acoustic Scenes | |
| 在果蝇翅膀上皮发育过程中，Frizzled1和Frizzled2在低Wingless水平下的竞争性生存中并非冗余。 | Hingole, S. | N/A | Frizzled1 and Frizzled2 are not redundant for competitive survival under low-Wingless levels in the developing Drosophila wing epithelium | |
| 重新审视生物医学研究中的胚胎鸡模型：一个科学案例 | McGrew, M. J. | N/A | A scientific case for revisiting the embryonic chicken model in biomedical research | |
| ANKRD5：轴丝的一个关键组成部分，对精子运动和男性生育能力至关重要 | Yu, S. | N/A | ANKRD5: a key component of the axoneme required for spermmotility and male fertility | |
| 通过血淋巴和环境DNA调查，在普吉特海湾的软壳蛤（Mya arenaria）中识别出双壳类可传播性肿瘤的暴发 | Weinandt, S. A. | N/A | Identification of an Outbreak of Bivalve Transmissible Neoplasia in Soft-Shell Clams (Mya arenaria) in the Puget Sound Using Hemolymph and eDNA Surveys | |
| 圈养繁殖野兔的饮食干预未能使肠道微生物群富集具有野生功能的微生物 | Aizpurua, O. | N/A | Dietary intervention in captive-bred hares fails to enrich gut microbiomes with wild-like functions | |
| 在非洲发现已驯化“迷幻蘑菇”Psilocybe cubensis 最亲近的野生近亲 | Bradshaw, A. J. | N/A | Discovery of the closest free-living relative of the domesticated "magic mushroom" Psilocybe cubensis in Africa | |
| 基于TurboID的邻近标记技术鉴定出维持秀丽隐杆线虫E颗粒完整性和小RNA稳态的新型生殖系蛋白 | Li, K. | N/A | TurboID-based proximity labeling identifies novel germline proteins that maintain E granule integrity and small RNA homeostasis in C. elegans | |
| 一种与腺苷淀粉样纤维形成相关的先天性代谢错误模型可减少TDP-43在酵母中的聚集和毒性 | Park, S. | N/A | A model of inborn metabolism errors associated with adenine amyloid-like fiber formation reduces TDP-43 aggregation and toxicity in yeast | |
| 条纹田鼠（Apodemus agrarius）的ERGA-BGE参考基因组，该物种在欧洲中部和东部广泛分布且数量众多。 | Janzekovic, F. | N/A | ERGA-BGE Reference Genome of the Striped Field Mouse (Apodemus agrarius), a Widespread and Abundant Species in Central and Eastern Europe | |
| 两种涉及EDN3的结构变异导致鸡的色素沉着过度 | Ma, C. | N/A | Two distinct structural variants involving EDN3 cause hyperpigmentation in chicken | |
| 人类基因组在核DNA和无细胞DNA中的覆盖情况 | Luo, J. | N/A | Coverage landscape of the human genome in nucleus DNA and cell-free DNA | |
| 乌干达和博茨瓦纳感染艾滋病毒的儿童中存在高KIR多样性 | John, M. | N/A | High KIR diversity in Uganda and Botswana children living with HIV | |
| 通过超滤纯化环状RNA | Cuevas, K. d. J. G. | N/A | Purifying circular RNA by ultrafiltration | |
| 工程化人体淋巴结基质模型用于研究间质液流和T细胞外排 | Hammel, J. H. | N/A | Engineered human lymph node stroma model for examining interstitial fluid flow and T cell egress | |
| 将无催化活性的RusA与FokI核酸酶融合，并结合PNA，可实现可编程的位点特异性双链DNA断裂 | Mahfouz, M. | N/A | Fusions of catalytically inactive RusA to FokI nuclease coupled with PNA enable programable site-specific double-stranded DNA breaks | |
| 调整组织模板及其细胞居民的机械环境，以指导机械适应性 | Putra, V. L. | N/A | Tuning mechanical milieux of tissue templates and their cellular inhabitants to guide mechanoadaptation | |
| Protein2Text：为蛋白质序列提供丰富的描述 | Dotan, E. | N/A | Protein2Text: Providing Rich Descriptions for Protein Sequences | |
| 癌症药物反应建模：蛋白质组学与转录组学的对比 | Zheng, Z. | N/A | Drug Response Modeling across Cancers: Proteomics vs. Transcriptomics | |
| 预测和注释鸡基因组中的替代转录起始位点和启动子移位 | Grushina, V. A. | N/A | Prediction and annotation of alternative transcription starts and promoter shift in the chicken genome | |
| 使用网络聚类算法进行细胞类型分化 | Fatemi Nasrollahi, F. S. | N/A | Cell Type Differentiation Using Network Clustering Algorithms | |
| 重复扩增障碍中CRISPR/Cas9靶向纳米孔测序方法的比较分析 | Benarroch, L. | N/A | Comparative analysis of CRISPR/Cas9-targeted nanopore sequencing approaches in repeat expansion disorders | |
| RIDDEN：从转录组数据中推断受体活性的数据驱动推理 | Barsi, S. | N/A | RIDDEN: Data-driven inference of receptor activity from transcriptomic data | |
| GraphVelo 允许推断多模态单细胞速度和分子机制 | Chen, Y. | N/A | GraphVelo allows inference of multi-modal single cell velocities and molecular mechanisms | |
| BindingGYM：一个大规模的突变数据集，旨在解析蛋白质-蛋白质相互作用 | Lu, W. | N/A | BindingGYM: A Large-Scale Mutational Dataset Toward Deciphering Protein-Protein Interactions | |
| 用于生物组织定量光学特性和色团浓度图像的深度集成模型 | Yan, B. | N/A | Deep Ensemble Model for Quantitative Optical Property and Chromophore Concentration Images of Biological Tissues | |
| 金复合物Auranofin使耐铂的上皮性卵巢癌细胞对顺铂敏感 | Abdalbari, F. H. | N/A | The gold complex auranofin sensitizes platinum resistant epithelial ovarian cancer cells to cisplatin | |
| 鹦形目中高密度和低密度脂蛋白胆固醇的血清脂质参考区间及其与动脉粥样硬化和其他因素的关联 | Janeczek, M. | N/A | Serum lipid reference intervals of high-density and low-density lipoprotein cholesterols and their association with atherosclerosis and other factors in Psittaciformes | |
| 苯代谢物通过激活热休克蛋白和Rho GTPase来增加血管通透性。 | Zelko, I. N. | N/A | Benzene metabolites increase vascular permeability by activating heat shock proteins and Rho GTPases | |
| 蛇毒金属蛋白酶主要负责某些非洲蝰蛇毒液的细胞毒性作用。 | Bartlett, K. E. | N/A | Snake venom metalloproteinases are predominantly responsible for the cytotoxic effects of certain African viper venoms | |
| 肾上腺皮质癌细胞对氧化铁纳米颗粒的摄取 | Challapalli, R. S. | N/A | Adrenocortical Cancer Cell uptake of Iron Oxide Nanoparticles | |
| ACKR3信号的淋巴激活调节缺血性心脏损伤后的淋巴反应。 | Balint, L. | N/A | Lymphatic activation of ACKR3 signaling regulates lymphatic response after ischemic heart injury. | |
| At-RS31 调控剪接因子的层级交叉调节，并将选择性剪接与TOR-ABA途径整合 | Koster, T. | N/A | At-RS31 orchestrates hierarchical cross-regulation of splicing factors and integrates alternative splicing with TOR-ABA pathways | |
| CAFE：一个综合性的网络应用程序，用于光谱流式细胞术中的高维度分析与可视化 | Siam, M. H. B. | N/A | CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry | |
| 参考组织的同时多因素贝叶斯分析（SiMBA）在PET时间活动曲线数据中的实现 | Matheson, G. J. | N/A | A Reference Tissue Implementation of Simultaneous Multifactor Bayesian Analysis (SiMBA) of PET Time Activity Curve Data | |
| 脑损伤后斑马鱼嗅觉系统的结构再生和功能恢复 | Calvo-Ochoa, E. | N/A | Structural regeneration and functional recovery of the olfactory system of zebrafish following brain injury | |
| 亚精胺通过调节应激反应缓解抑郁 | Mackert, S. | N/A | Spermidine alleviates depression via control of the stress response | |
| 小鼠方偏差：在规则修订模型中的审议决策揭示了小鼠中类似“我方”确认偏差的认知过程。 | Stevens, C. | N/A | Mice-side bias: Deliberative decision making in a model of rule revision reveals 'myside' confirmation bias-like cognitive processes in mice. | |
| 皮层动力学在快速步态启动中的作用，涉及不同的姿势需求 | Giesbers, I. | N/A | Cortical dynamics underlying initiation of rapid steps with contrasting postural demands | |
| 快感不足？幻觉倾向对积极自我语音感觉反馈处理的影响 | Duggirala, S. X. | N/A | Not enough pleasure? Influence of hallucination proneness on sensory feedback processing of positive self-voice | |
| 从子宫到摇篮：胎儿在子宫内的活动模式如何揭示出生后的睡眠行为 | Markovic, A. | N/A | From womb to crib: How fetal activity patterns in utero reveal postnatal sleep behavior | |
| 规模多样性、丰度和能量：生物多样性动态的平衡理论 | Storch, D. | N/A | Scaling diversity, abundance and energy: the Equilibrium Theory of Biodiversity Dynamics | |
| 利用贝叶斯分层模型结合声学遥测、生物学和环境数据评估溯河性鲑科鱼类的存活率 | Munaweera, I. | N/A | Estimating survival of an anadromous salmonid using Bayesian hierarchical models applied to acoustic telemetry, biological, and environmental data | |
| 通过谱系学视角看幻影上位 | Ignatieva, A. | N/A | Phantom epistasis through the lens of genealogies | |
| 环境诱导的精子sRNA变异与斑马鱼后代的基因表达和转座元件相关 | Godden, A. M. | N/A | Environmentally induced variation in sperm sRNAs is linked to gene expression and transposable elements in zebrafish offspring | |
| 在更新世乳齿象的边缘种群中，气候驱动的扩散和物种形成反复发生。 | Karpinski, E. | N/A | Repeated climate-driven dispersal and speciation in peripheral populations of Pleistocene mastodons | |
| 生活在不同气候带的北极熊亚种群之间转座子活性差异 | Godden, A. M. | N/A | Diverging transposon activity among polar bear sub-populations inhabiting different climate zones | |
| 在Podospora anserina中，MAT近端区域的遗传分化并不足以抑制重组 | Grognet, P. | N/A | Genetic differentiation in the MAT-proximal region is not sufficient for suppressing recombination in Podospora anserina | |
| 色素沉着与视网膜色素上皮厚度：一项研究眼内与眼外色素组织表型与基因型关系的研究。 | Julian, T. H. | N/A | Pigmentation and retinal pigment epithelium thickness: a study of the phenotypic and genotypic relationships between ocular and extraocular pigmented tissues. | |
| 一种模拟人类LDLR相关动脉粥样硬化的猫科动物模型 | Hytonen, M. K. | N/A | A feline model of human LDLR-related atherosclerosis | |
| 大肠杆菌中补骨脂素-链间交联抗性的复杂发展需要AcrR失活、保留marbox序列以及MarA、SoxS或Rob全球调控因子中的一个。 | Worley, T. K. | N/A | The complex development of psoralen-interstrand crosslink resistance in Escherichia coli requires AcrR inactivation, retention of a marbox sequence, and one of three MarA, SoxS, or Rob global regulators | |
| 功能基因组学验证PPARγ信号在肺动脉平滑肌细胞中的作用：对肺动脉高压治疗的启示 | Su, R. | N/A | Functional Genomics Validation of PPAR gamma Signalling in PASMCs: Therapeutic Implications for Pulmonary Arterial Hypertension | |
| 埃及伊蚊全线粒体基因组分析揭示与沃尔巴克氏菌感染的关联 | Gupta, B. | N/A | Whole mitochondrial genome analysis of Aedes aegypti reveal association with Wolbachia infection | |
| 预测多肽结构构象与AlphaFold2 | Ille, A. M. | N/A | Prediction of peptide structural conformations with AlphaFold2 | |
| 使用混合数据集中的二维电导率概率分布进行遗传序列识别的机器学习框架 | Wang, Y. | N/A | A ML Framework for Genetic Sequence Identification using 2D Electrical Conductance Probability Distributions from Mixed Data Sets | |
| GRU-SCANET：释放基于GRU的正弦捕获网络在精准命名实体识别中的潜力 | Happi Happi, B. G. | N/A | GRU-SCANET: Unleashing the Power of GRU-based Sinusoidal CApture Network for Precision-driven Named Entity Recognition | |
| 体外β2肾上腺素受体刺激下BPH-1细胞的神经内分泌分化 | PIGAT, N. | N/A | In vitro neuroendocrine differentiation of BPH-1 cells under beta2 adrenergic receptor stimulation | |
| 小鼠膀胱癌中多谱系肿瘤细胞群体的图谱绘制 | Schrode, N. | N/A | Mapping of Multilineage Tumor Cell Populations in Mouse Bladder Cancer | |
| SUMO抑制加上CD40激动剂通过干扰素介导的巨噬细胞激活增加了抗肿瘤免疫原性 | Li, K. Y. | N/A | SUMO Inhibition Plus CD40 Agonism Increases Anti-Tumor Immunogenicity Through Interferon Mediated Macrophage Activation | |
| 在详细的皮层模型中，尖峰分类偏差和信息丢失 | Laquitaine, S. | N/A | Spike sorting biases and information loss in a detailed cortical model | |
| TRPM7活性以依赖镁的方式驱动人类CD4 T细胞的激活和分化 | Madlmayr, A. | N/A | TRPM7 activity drives human CD4 T-cell activation and differentiation in a magnesium dependent manner | |
| 在组织工程平台上协同生成心脏驻留样巨噬细胞和心肌细胞成熟 | Suku, M. | N/A | Synergistic generation of cardiac resident-like macrophages and cardiomyocyte maturation in tissue engineered platforms | |
| 破坏基底CXCR4寡聚体损害淋巴瘤中的致癌特性 | Mobach, S. | N/A | Disruption of basal CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms | |
| 建立可靠的小鼠三甲胺N-氧化物状态血液生物标志物：口服胆碱挑战、饮食胆碱和禁食条件的影响 | Din, A. U. | N/A | Establishing reliable blood biomarkers for trimethylamine N-oxide status in rodents: effects of oral choline challenge, dietary choline and fasting conditions | |
| 将多样化的生物活性数据整合到化学检查器化合物宇宙中 | Comajuncosa-Creus, A. | N/A | Integration of diverse bioactivity data into the Chemical Checker compound universe | |
| MerQuaCo：一种基于图像的空间转录组学质量控制计算工具 | Martin, N. X. | N/A | MerQuaCo: a computational tool for quality control in image-based spatial transcriptomics | |
| 布卡·德拉·伊纳和格罗塔·德尔·卡普里奥洛：对意大利中部两个晚期穆斯特文化遗址的新年代学、石器和动物群分析 | Gennai, J. | N/A | Buca della Iena and Grotta del Capriolo: new chronological, lithic, and faunal analyses of two late Mousterian sites in Central Italy | |
| 果蝇中一种用于情境依赖的多模态信号传递的神经回路 | Steinfath, E. | N/A | A neural circuit for context-dependent multimodal signaling in Drosophila | |
| lenacapavir通过一种主要机制实现对HIV-1成熟过程的高度有效抑制。 | Huang, S.-W. | N/A | The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir | |
| 鱼精蛋白的抗真菌活性 | Kumarasamy, A. | N/A | Antifungal activity of protamine | |
| 植物来源的代谢物与根际微生物群功能的相互作用增强了干旱胁迫耐受性 | Kazarina, A. | N/A | Interaction of plant-derived metabolites and rhizobiome functions enhances drought stress tolerance | |
| 基质孔隙度与假体关节感染期间金黄色葡萄球菌生物膜的存活有关。 | Bhattacharya, M. | N/A | Matrix porosity is associated with Staphylococcus aureus biofilm survival during prosthetic joint infection | |
| 在B族链球菌中进行的CRISPRi文库筛选鉴定出表面免疫原性蛋白（Sip）作为多种宿主相互作用的中介因子。 | Firestone, K. | N/A | A CRISPRi Library Screen in Group B Streptococcus Identifies Surface Immunogenic Protein (Sip) as a Mediator of Multiple Host Interactions | |
| 施肥对草地食物链中的微生物群落产生影响 | Jetter, K. | N/A | Fertilization impacts microbiomes along the grassland trophic chain | |
| 敲除仅在排泄腺细胞中表达的所有线虫特异性NSPC基因，会导致转录组特征表明胰岛素信号传导受到影响。 | Mackiewicz, Z. | N/A | Knockout of all nematode-specific NSPC genes expressed exclusively in the excretory gland cell results in transcriptomic signatures indicating an affected insulin signaling | |
| PER2蛋白表达减少导致β1-AA诱导的心脏自噬节律紊乱 | Li, P. | N/A | Reduced expression of PER2 protein contrbutes to β1-AA induced cardiac autophagy rhythm disorder | |
| 不同相互作用类型的生态网络在生物地理尺度上具有模块性，并且高度依赖于采样强度。 | Garcia-Callejas, D. | N/A | Ecological networks across interaction types are modular and highly driven by sampling intensity at biogeographical scales | |
| 蛋白质进化中的波动与可预测性极限 | Rossi, S. | N/A | Fluctuations and the limit of predictability in protein evolution | |
| 一般人群中的亲代间基因转换：一种新的杂合性丧失机制 | Toratani, J. | N/A | Interparental Gene Conversion in General Population: A Novel Mechanism For Loss of Heterozygosity | |
| 一氧化氮通过Rab5的S-亚硝基化调节吞噬作用 | Hagiwara, M. | N/A | Nitric oxide regulates phagocytosis through S-nitrosylation of Rab5 | |
| 基于大环降解剂BTR2004对CUL3KLHL20驱动的BET家族BRD蛋白靶向降解的时间和空间特性研究 | Yeh, J. | N/A | Temporal and Spatial Characterization of CUL3KLHL20-driven Targeted Degradation of BET family, BRD Proteins by the Macrocycle-based Degrader BTR2004 | |
| 设计白细胞介素-21模拟物的强大抗癌活性 | Chun, J.-H. | N/A | Potent antitumor activity of a designed interleukin-21 mimic | |
| 用于冷冻电镜和冷冻电子断层扫描中方向估计的贝叶斯视角 | Xu, S. | N/A | Bayesian Perspective for Orientation Estimation in Cryo-EM and Cryo-ET | |
| 由NKX2-1调控的表观遗传重塑和三维染色质重构推动神经内分泌前列腺癌的发展。 | Lu, X. | N/A | Epigenetic remodeling and 3D chromatin reorganization governed by NKX2-1 drive neuroendocrine prostate cancer | |
| 发现新型选择性GPR17拮抗剂作为开发糖尿病和肥胖症新治疗策略的药理工具 | Zhu, H. | N/A | Discovery of Novel and Selective GPR17 Antagonists as Pharmacological Tools for Developing New Therapeutic Strategies in Diabetes and Obesity | |
| 小麦白粉病菌（Zymoseptoria tritici）的隐匿感染是通过阶段特异性下调β-葡聚糖酶来实现的。 | Rebaque, D. | N/A | Zymoseptoria tritici stealth infection is facilitated by stage-specific down-regulation of a β-glucanase | |
| 陆生植物中果胶裂解酶样基因的进化及其在寄生植物吸器形成中的作用 | Zhang, H. | N/A | The evolution of pectate lyase-like genes across land plants, and their roles in haustorium formation in parasitic plants | |
| 一步法生物催化级联反应从醛或羧酸制备多种L-苯丙氨酸衍生物 | Anderson, S. R. | N/A | A One-Pot Biocatalytic Cascade to Access Diverse L-Phenylalanine Derivatives from Aldehydes or Carboxylic Acids | |
| MCSPACE：从高通量共定位数据推断微生物组的时空动态 | Uppal, G. | N/A | MCSPACE: inferring microbiome spatiotemporal dynamics from high-throughput co-localization data | |
| 家庭环境中的病原体和抗菌药物耐药基因：孟加拉国农村土壤地板和牛粪研究 | Nguyen, A. T. | N/A | Pathogens and Antimicrobial Resistance Genes in Household Environments: A Study of Soil Floors and Cow Dung in Rural Bangladesh | |
| 全基因组分析大肠杆菌对次硫氰酸盐胁迫的响应，揭示RclB和RclC可能降低细胞膜通透性的作用 | Meredith, J. D. | N/A | Genome-wide characterization of hypothiocyanite stress response of Escherichia coli reveals a potential role for RclB and RclC in lowering cell envelope permeability | |
| 通过HIV-1编码的反义转录本实现表观遗传沉默及潜伏逆转的阻断 | Li, R. | N/A | Epigenetic silencing and blockade of latency reversal by an HIV-1 encoded antisense transcript | |
| 成年蜂王食用花粉和花蜜。 | St. Clair, A. | N/A | Adult honey bee queens consume pollen and nectar | |
| # BioRxiv 2024-12-06 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 图像平衡是一种自下而上的神经美学特性，介导着注意力和眼球运动。一个原始的视觉操作系统解释了平衡的属性，以及一种基本的视觉组织世界的方式。 | Corwin, D. M. | N/A | Pictorial balance is a bottom-up neuro-aesthetic property mediating attention and eye movements. A primitive visual operating system explains the property of balance and a primary visual way of organizing the world. | |
| 端粒酶依赖性斑马鱼大脑衰老 | Martins, R. R. | N/A | Telomerase-Dependent Ageing In The Zebrafish Brain | |
| 有丝分裂神经母细胞的检测为成年小肠肌间神经丛中持续的神经发生提供了额外证据。 | Gorecki, A. M. | N/A | Detection of mitotic neuroblasts provides additional evidence of steady state neurogenesis in the adult small intestinal myenteric plexus | |
| TriScan：采用简单光学设计的快速、高灵敏度三维共聚焦荧光成像技术 | Van den Eynde, R. | N/A | The TriScan: fast and sensitive 3D confocal fluorescence imaging using a simple optical design | |
| 神经活动跨学科映射与受限玻尔兹曼机 | Yang, H. | N/A | Cross-subject Mapping of Neural Activity with Restricted Boltzmann Machines | |
| 依赖于偏心率的扫视反应时间：中央凹放大和注意定向的作用 | Zhang, Y. | N/A | Eccentricity-Dependent Saccadic Reaction Time: The Roles of Foveal Magnification and Attentional Orienting | |
| 神经网络在认知任务期间被调整至接近临界状态，而在阿尔茨海默病的精神药理学模型中则远离临界状态 | Habibollahi, F. | N/A | Neural Networks Are Tuned Near Criticality During a Cognitive Task and Distanced from Criticality In a Psychopharmacological Model of Alzheimer's Disease | |
| 在季节性缩小的过程中，白足鼩鼱的动态代谢和分子变化 | Thomas, W. R. | N/A | Dynamic metabolic and molecular changes during seasonal shrinking in Sorex araneus | |
| 硬骨鱼类幼体中多样的捕食策略 | Mearns, D. S. | N/A | Diverse prey capture strategies in teleost larvae | |
| DNA损伤检查点1（MDC1）的共调节活性与乳腺小叶癌中的DNA修复功能障碍及PARP抑制剂敏感性相关 | Sottnik, J. L. | N/A | Co-regulator activity of Mediator of DNA Damage Checkpoint 1 (MDC1) is associated with DNA repair dysfunction and PARP inhibitor sensitivity in lobular carcinoma of the breast | |
| 使用正未标注机器学习识别人类mRNA 5'UTR序列中的潜在核开关元件 | Raymond, W. | N/A | Identification of potential riboswitch elements in Homo Sapiens mRNA 5'UTR sequences using Positive-Unlabeled Machine learning | |
| 脂肪酸代谢和氧化应激反应支持细菌捕食 | Jain, R. | N/A | Fatty Acid Metabolism and The Oxidative Stress Response Support Bacterial Predation | |
| LysM-RLK在植物中发挥着古老的共生功能 | Teyssier, E. | N/A | LysM-RLK plays an ancestral symbiotic function in plants | |
| 重组Physcomitrella FtsZ蛋白在体外依赖GTP的差异聚合作用 | Milferstaedt, S. W. L. | N/A | Differential GTP-dependent in-vitro polymerization of recombinant Physcomitrella FtsZ proteins | |
| POMC神经元通过在Kisspeptin神经元中对MC4R的不同信号传导来控制生育能力。 | Talbi, R. | N/A | POMC neurons control fertility through differential signaling of MC4R in Kisspeptin neurons | |
| 一个反馈驱动的脑类器官平台能够实现自动维护和高分辨率神经活动监测 | Voitiuk, K. | N/A | A feedback-driven brain organoid platform enables automated maintenance and high-resolution neural activity monitoring | |
| 40S核糖体蛋白RPS26和RPS25的不足，在脆性X相关条件下，对含聚甘氨酸蛋白的生物合成产生负面影响。 | Tutak, K. | N/A | Insufficiency of 40S ribosomal proteins, RPS26 and RPS25, negatively affects biosynthesis of polyglycine-containing proteins in fragile-X associated conditions | |
| Wnt通路调控的细胞外基质蛋白聚糖的表达在东非慈鲷脂肪组织肥大的平行进化中起着重要作用。 | Machii, N. | N/A | Pronounced expression of extracellular matrix proteoglycans regulated by Wnt pathway underlies the parallel evolution of lip hypertrophy in East African cichlids | |
| 成像流式细胞术能够实现从不可培养的细菌群体中对形态变异细胞的无标记分选。 | Vocelle, D. | N/A | Imaging flow cytometry enables label-free cell sorting of morphological variants from unculturable bacterial populations. | |
| 新型酿酒酵母群落生态发酵研究模型设计 | Pourcelot, E. | N/A | Design of a new model yeast consortium for ecological studies of enological fermentation | |
| 使用信息先验来解决存在鉴定错误的占据模型中的可识别性问题 | Monchy, C. | N/A | Using informative priors to account for identifiability issues in occupancy models with identification errors | |
| 在预测编码模型中平衡先验知识和感官数据：对精神分裂症中连贯运动检测的洞察 | Nemati, E. | N/A | Balancing Prior Knowledge and Sensory Data in a Predictive Coding Model: Insights into Coherent Motion Detection in Schizophrenia | |
| 动态调节小鼠海马体中由学习与记忆介导的NAT10介导的突触mRNA乙酰化 | Zhou, H.-Q. | N/A | Dynamic regulation of NAT10-mediated mRNA acetylation at synapses by learning and memory in mouse hippocampus | |
| PathoGFAIR：一套符合FAIR原则且可适应的（元）基因组工作流程，用于（食源性）病原体的检测和追踪 | Nasr, E. | N/A | PathoGFAIR: a collection of FAIR and adaptable (meta)genomics workflows for (foodborne) pathogens detection and tracking | |
| 神经网络中模块性的出现与维持：基于Hebbian和反Hebbian抑制性STDP | Bergoin, R. | N/A | Emergence and maintenance of modularity in neural networks with Hebbian and anti-Hebbian inhibitory STDP | |
| 大规模并行遗传扰动揭示了淀粉样β核化反应的能量结构 | Arutyunyan, A. | N/A | Massively parallel genetic perturbation reveals the energetic architecture of an amyloid beta nucleation reaction | |
| C-C趋化因子受体4缺乏加剧了小鼠早期动脉粥样硬化 | Tanaka, T. | N/A | C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice | |
| 预测无关信息：分心物可预测性的神经效应取决于任务负荷 | Lui, T. K.-Y. | N/A | Predicting the irrelevant: Neural effects of distractor predictability depend on load | |
| 面部表情和言语运动中的时空结构与子状态 | Cuve, H. C. J. | N/A | Spatiotemporal structure and substates in facial expressions and speech movements | |
| 关于蛋白质遗传结构分析：对“蛋白质序列景观并非如此简单”的回应 | Park, Y. | N/A | On the Analysis of Protein Genetic Architecture: Response to "Protein sequence landscapes are not so simple" | |
| 解码HIV诱导的CPSF6斑点的生物发生及其与核斑点的融合 | Tomasini, C. | N/A | Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle | |
| 用于神经场体内双光子荧光显微镜的自适应光学校正 | Kang, I. | N/A | Adaptive optical correction for in vivo two-photon fluorescence microscopy with neural fields | |
| 认知网络通过通信子空间在大规模新皮层模型中的交互作用 | Pereira-Obilinovic, U. | N/A | Cognitive networks interactions through communication subspaces in large-scale models of the neocortex | |
| 一个具有广泛宿主范围的锈菌中，假定效应因子的基因组内变异驱动了早期感染阶段 | Degnan, R. | N/A | Intragenomic variants of a putative effector drive early-stage infection in a broad host-range rust fungus | |
| 利用新型病毒工具探索CA3记忆细胞性质的早期变化 | Cupolillo, D. | N/A | Early changes in the properties of CA3 engram cells explored with a novel viral tool | |
| 识别基孔肯雅病毒nsP2 ATPase抑制剂 | Navarro, H. | N/A | Identification of Inhibitors of Chikungunya virus nsP2 ATPase | |
| 大规模信息先验用于更好地预测稀有树相关微生境的局部发生率 | Cottais, P. | N/A | Large-scale informative priors to better predict the local occurrence rate of a rare tree-related microhabitat | |
| 语言网络揭示了由基于结构域的词语构成的蛋白质句子的语法约束 | Shimpi, A. A. | N/A | Linguistic networks uncover grammatical constraints of protein sentences comprised of domain-based words | |
| BEVA2.0：通过模块化组装扩展遗传工程应用的金门兼容载体系统 | Geddes, B. A. | N/A | BEVA2.0: Modular Assembly of Golden Gate-Compatible Vectors with Expanded Utility for Genetic Engineering | |
| CGC1，一种新的秀丽隐杆线虫参考基因组 | Ichikawa, K. | N/A | CGC1, a new reference genome for Caenorhabditis elegans | |
| 评估基因表达综合数据库（GEO）数据集中的偏差 | Gondal, M. N. | N/A | Assessing Bias in Gene Expression Omnibus (GEO) Datasets | |
| 在蛋白质结构标记器中平衡局部性与重构性 | Zhang, J. | N/A | Balancing Locality and Reconstruction in Protein Structure Tokenizer | |
| 哺乳至断奶过渡期间肠道上皮转录组变化的单细胞图谱 | Malonga, T. | N/A | A single-cell atlas of transcriptome changes in the intestinal epithelium at the suckling-to-weaning transition | |
| 颌口类（Gnathostomata）胃的进化：通过基因组损失的研究发现——无胃物种的启示 | Dann, J. B. | N/A | Evolution of the Jawed Vertebrate (Gnathostomata) Stomach through Gene Repertoire Loss: Findings from Agastric Species | |
| MOZ和HBO1组蛋白乙酰转移酶复合物是NUP98重排急性髓系白血病的分子依赖性和治疗靶点 | Michmerhuizen, N. L. | N/A | MOZ and HBO1 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia | |
| 果蝇大脑中已鉴定神经元的突触图谱分析 | Wu, H. | N/A | Synapse profiling of identified neurons in the Drosophila brain | |
| 章鱼胺信号协调果蝇蘑菇体中突触前机制的空间模式 | Wu, H. | N/A | Octopamine signals coordinate the spatial pattern of presynaptic machineries in the Drosophila mushroom bodies | |
| 高通量定量miRNA-3'-非翻译区调控效应 | Mastriano, S. | N/A | High-Throughput Quantification of miRNA-3'-Untranslated-Region Regulatory Effects | |
| 在秀丽隐杆线虫中对Rab GTPase基因进行RNAi筛选发现，生殖系统的体细胞在形态发生过程中依赖于rab-1，但在干细胞龛位的维持中并不依赖于rab-1。 | Scott, K. F. | N/A | An RNAi screen of Rab GTPase genes in C. elegans reveals that somatic cells of the reproductive system depend on rab-1 for morphogenesis but not stem cell niche maintenance | |
| 不同的分化轨迹对V2a中间神经元的基因调控和功能产生持久影响。 | Elder, N. H. | N/A | Distinct differentiation trajectories leave lasting impacts on gene regulation and function of V2a interneurons | |
| 立克次氏菌细菌的比较基因组学揭示了与节肢动物共生相互作用中涉及的可变代谢特征 | Floriano, A. M. M. | N/A | Comparative genomics of Rickettsiella bacteria reveal variable metabolic traits involved in symbiotic interactions with arthropods | |
| 利用从头设计的蛋白质抑制致病性大肠杆菌的血红素盗取 | Fox, D. R. | N/A | Inhibiting heme-piracy by pathogenic Escherichia coli using de novo-designed proteins | |
| CRISPR-Cas13高效抑制剂的从头设计 | Taveneau, C. | N/A | De novo design of potent CRISPR-Cas13 inhibitors | |
| 基于亮氨酸拉链的SAIM成像技术可识别用于破坏癌细胞糖萼以增强免疫治疗的药物 | Park, S. | N/A | Leucine zipper-based SAIM imaging identifies therapeutic agents to disrupt the cancer cell glycocalyx for enhanced immunotherapy | |
| 水溶性CD20抗原的设计与计算表位支架构建 | Yao, Z. | N/A | Design of a Water-Soluble CD20 Antigen with Computational Epitope Scaffolding | |
| IP6阴离子结合对HIV-1衣壳组装分子开关的动态影响 | Gupta, M. | N/A | Kinetic Implications of IP6 Anion Binding on the Molecular Switch of the HIV-1 Capsid Assembly | |
| 结核分枝杆菌CrgA形成二聚体结构，其跨膜结构域夹在胞质和周质β片层之间，从而能够与多个分裂体蛋白进行多重相互作用。 | Shin, Y. | N/A | Mycobacterium tuberculosis CrgA Forms a Dimeric Structure with Its Transmembrane Domain Sandwiched between Cytoplasmic and Periplasmic β-Sheets, Enabling Multiple Interactions with Other Divisome Proteins | |
| PIP2激活和SEA0400抑制在人类心脏钠钙交换体NCX1中的结构机制 | Xue, J. | N/A | Structural mechanisms of PIP2 activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1 | |
| 多尺度建模展示了细胞-细胞外基质相互作用如何影响细胞外基质纤维排列和细胞脱离 | Arellano-Tinto, J. | N/A | Multiscale modelling shows how cell-ECM interactions impact ECM fibre alignment and cell detachment | |
| 小热休克蛋白客户隔离与诱导多分散性的机制 | Miller, A. P. | N/A | Mechanism of small heat shock protein client sequestration and induced polydispersity | |
| 基于微阀的免流梯度发生器 | Bohec, P. | N/A | Microvalve-based devices for flow-free gradient generators | |
| 明确分配弯曲的β片层有助于深入理解生物分子凝聚物中可逆性的分子语法 | Roy, I. | N/A | Unambiguous assignment of kinked beta sheets leads to insights into molecular grammar of reversibility in biomolecular condensates | |
| 登革病毒非结构5（NS5）与启动子茎环A（SLA）相互作用的结构动力学 | Obi, J. O. | N/A | Structural Dynamics of the Dengue Virus Non-structural 5 (NS5) Interactions with Promoter Stem Loop A (SLA) | |
| CIGB-300在肺鳞状细胞癌蛋白质组学中的时间依赖性和剂量依赖性效应。 | Garcia, L. E. | N/A | Time- and Dose-dependent Effects of CIGB-300 in the lung squamous cell carcinoma proteomics. | |
| 膜相关泛素连接酶MARCHF8通过降解MHC I类蛋白促进癌症免疫逃逸 | Khalil, M. I. | N/A | The membrane-associated ubiquitin ligase MARCHF8 promotes cancer immune evasion by degrading MHC class I proteins | |
| 人类mGlu5变构调节剂的药理学特征 | Razzak, M. | N/A | Pharmacological characterisation of allosteric modulators at human mGlu5 | |
| 来自乌克兰东部不同R-E半克隆种群系统的Pelophylax水蛙的杂交生殖：选择性死亡率、克隆和倍性多样性 | Fedorova, A. | N/A | Hybridogenetic reproduction of Pelophylax water frogs from different R-E hemiclonal population systems from Eastern Ukraine: selective mortality, clonal and ploidy diversity | |
| 在腰果占主导地位的生物多样性热点地区，种植园内及周边森林覆盖的本地树木对鸟类保护至关重要。 | Madhu, N. | N/A | Native trees within plantations and surrounding forest cover are essential for bird conservation in cashew-dominated landscapes within a biodiversity hotspot | |
| 伊维菌素在秀丽隐杆线虫（Caenorhabditis elegans）这一线虫模型中的抗性进化：种群大小的重要影响及对依莫德吡的意外交叉抗性 | Hellinga, J. | N/A | Evolution of ivermectin resistance in the nematode model Caenorhabditis elegans: critical influence of population size and unexpected cross-resistance to emodepside | |
| 尿道双J导管复杂微生物群落的表型特征及细菌相互作用 | Farizano, J. V. | N/A | PHENOTYPIC CHARACTERIZATION AND BACTERIAL INTERACTIONS OF THE COMPLEX MICROBIAL POPULATION IN URINARY DOUBLE-J CATHETERS | |
| 铜绿假单胞菌（Pseudomonas aeruginosa）对血清素、多巴胺、肾上腺素和去甲肾上腺素表现出趋化性。 | Monteagudo-Cascales, E. | N/A | Pseudomonas aeruginosa performs chemotaxis to serotonin, dopamine, epinephrine, and norepinephrine | |
| 特定阶段的预运动抑制调节了水蛭的节律性运动输出 | Radice, M. | N/A | Phase-specific premotor inhibition modulates leech rhythmic motor output | |
| 糖蛋白pherophorin II的时空分布揭示了Volvox carteri生长中的细胞外基质的随机几何结构 | von der Heyde, B. | N/A | Spatiotemporal distribution of the glycoprotein pherophorin II reveals stochastic geometry of the growing ECM of Volvox carteri | |
| 模拟为贝特曼梯度提供了机制性解释。 | Sanghvi, K. | N/A | Simulations provide a mechanistic interpretation of Bateman gradients | |
| 从色素到精准：探索小麦和大麦的基因转化与基因组编辑 | Prusty, M. R. | N/A | From Pigments to Precision: Exploring Genetic Transformation and Genome Editing in Wheat and Barley | |
| R-环语法预测了在不同拓扑约束下R-环的形成。 | Ferrari, M. M. | N/A | The R-loop Grammar predicts R-loop formation under different topological constraints | |
| 在成年期，目标导向导航的认知和运动能力下降是可分离的，并贯穿整个生命周期。 | LAncia, G. L. | N/A | Separable cognitive and motor decline tracked across adult life-span for goal-directed navigation | |
| 利用下一代测序数据的生物信息学分析，鉴定与阿尔茨海默病相关的候选生物标志物和信号通路 | Vastrad, B. M. | N/A | Identification of candidate biomarkers and signaling pathways associated with Alzheimer's disease using bioinformatics analysis of next generation sequencing data | |
| 用于从单细胞转录组数据预测样本表型的可解释深度神经网络 | Martorell-Marugan, J. | N/A | Explainable deep neural networks for predicting sample phenotypes from single-cell transcriptomics | |
| GJB3是一种缝隙连接基因，通过介导胱氨酸摄取和调节细胞应激途径，支持SLC7A11低表达的腺癌中的细胞生长。 | Acharya, D. | N/A | GJB3, a gap junction gene, supports cell growth by mediating cystine uptake and regulating cellular stress pathways in SLC7A11 low adenocarcinomas | |
| DeepGraphMut：一种基于图的深度学习方法，利用体细胞突变谱进行癌症预后分析 | Jose, A. | N/A | DeepGraphMut: A graph-based deep learning methodfor cancer prognosis using somatic mutation profile | |
| 2024年荷兰蓝舌病毒12型 - 首次在欧洲报告的蓝舌病毒血清型 | van den Brom, R. | N/A | Bluetongue virus serotype 12 in the Netherlands in 2024 - A BTV serotype reported in Europe for the first time | |
| 自愿行为能增强感官预测能力，并促进对相关感官刺激的神经处理。 | Ody, E. | N/A | Voluntary action sharpens sensory prediction and facilitates neural processing of contingent sensory stimuli | |
| 在自身免疫性脱髓鞘模型中揭示的变节抗体：从生物学到治疗 | Taghipour-Mirakmahaleh, R. | N/A | Turncoat antibodies unmasked in a model of autoimmune demyelination: from biology to therapy | |
| 乳酸乳球菌亚种乳脂亚种C60通过功能性修饰树突状细胞，创造了一种以I型调节性T细胞为主导的抗炎肠道环境。 | Saito, S. | N/A | Lactococcus lactis subsp. cremoris C60 creates a type I regulatory T cell-dominant anti-inflammatory intestinal environment through functional modification of dendritic cells | |
| 三种Candidatus Liberibacter solanacearum载体（Dyspersa apicalis、Dyspersa pallida和Trioza urticae）的染色体水平组装（半翅目：瘿蚊科） | Heaven, T. | N/A | Chromosome-level Assemblies of Three Candidatus Liberibacter solanacearum Vectors: Dyspersa apicalis, Dyspersa pallida, and Trioza urticae (Hemiptera: Psylloidea) | |
| 通过长读长测序进行血红蛋白病变异的综合检测 | Xiang, J. | N/A | The comprehensive detection of hemoglobinopathy variants via long-read sequencing | |
| 人类肠道微生物群中两个关键的放线菌门分类群与曼氏血吸虫感染负担相关 | Appiah-Twum, F. | N/A | Two Key Actinomycetota Taxa in the Human Gut Microbiota are Associated with Schistosoma mansoni Infection Burden | |
| 电影间的差异性严重限制了“自然主义”神经影像学研究结果的可推广性。 | Leipold, S. | N/A | Between-movie variability severely limits generalizability of "naturalistic" neuroimaging | |
| Dnmt3a介导的新生甲基化平衡了Th1和Tfh记忆细胞的可塑性和功能性。 | Perkins, B. | N/A | Dnmt3a-mediated de novo methylation balances Th1 and Tfh memory cell plasticity and functionality | |
| Tokenvizz：基于GraphRAG的基因组数据发现与可视化标记化工具 | Oguztuzun, C. | N/A | Tokenvizz: GraphRAG-Inspired Tokenization Tool for Genomic Data Discovery and Visualization | |
| 同时抑制MDM2和PARP在p53野生型横纹肌肉瘤模型中产生协同抗肿瘤效应 | Pons, G. | N/A | Combined inhibition of MDM2 and PARP lead to a synergistic anti-tumoral response in p53 wild-type rhabdomyosarcoma models | |
| 运动可以缓解肝脏衰老，但在饮食诱导的MASLD中，其效果并不优于饮食限制。 | Katsarou, A. | N/A | Exercise alleviates liver senescence but does not outmatch the effect of dietary restriction in diet-induced MASLD | |
| 一种用于急性视网膜外植体中光感受器和神经节细胞联合功能评估的方法 | He, X. | N/A | A Method for the Combined Functional Assessment of Photoreceptors and Ganglion Cells in Acute Retinal Explants | |
| 紧张性冷痛的神经动力学：对健康个体在扫描仪内冷压测试替代方法的新研究 | Medina, S. | N/A | Neural Dynamics of Tonic Cold Pain: A Novel Investigation of an In-Scanner Alternative to the Cold Pressor Test in Healthy Individuals | |
| 空间注意力和特征选择性注意力相互作用，驱动前顶叶皮层的选择性编码 | Dermody, N. | N/A | Spatial and feature-selective attention interact to drive selective coding in frontoparietal cortex | |
| 使用CellREADR在人脑皮层中进行RNA可编程的细胞类型监测与操控 | Matthews, E. A. | N/A | RNA-programmable cell type monitoring and manipulation in the human cortex with CellREADR | |
| 捕获SARS-CoV-2刺突蛋白融合中间构象需要受体结合以及在S1/S2或S2'位点的切割 | Lusvarghi, S. | N/A | Capture of fusion-intermediate conformations of SARS-CoV-2 spike requires receptor binding and cleavage at either the S1/S2 or S2' site | |
| SARS-CoV-2对高尔基体结合的PI4P的捕食，引发了细胞质中DNA损伤反应激酶ATM的大规模激活。 | Rebendenne, A. | N/A | SARS-CoV-2 predation of Golgi-bound PI4P primes the massive activation of the DNA Damage Response kinase ATM in the cytoplasm | |
| 高效地利用CUT&RUN技术进行染色质相关靶点的基因组定位 | Firestone, T. M. | N/A | High-efficiency genomic mapping of chromatin-associated targets with CUT&RUN | |
| 滞留短新生链测序揭示了布氏锥虫中真核DNA复制起源的拓扑结构。 | STANOJCIC, S. | N/A | Stranded short nascent strand sequencing reveals the topology of eukaryotic DNA replication origins in Trypanosoma brucei. | |
| 发育程序推动细胞可塑性、疾病进展和肺腺癌中的治疗抵抗 | Bienkowska, K. J. | N/A | Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma | |
| 白血病细胞内在和外在因素相互协作，促进了KMT2A重排的B-ALL在中枢神经系统（CNS）微环境中的生存和增殖。 | Duguid, A. | N/A | Leukaemia cell intrinsic and extrinsic factors cooperate to facilitate the survival and proliferation of KMT2A-rearranged B-ALL in the CNS niche. | |
| IGFs调控前列腺癌中的癌细胞免疫逃逸 | Nandakumar, A. M. | N/A | IGFs regulate cancer cell immune evasion in prostate cancer | |
| 转用电子烟可恢复吸烟小鼠对屋尘螨的免疫反应。 | Warren, K. J. | N/A | Transitioning to e-cigarettes restores the immune response to house dust mite in cigarette smoked mice. | |
| 一个用于探索海草生态系统中细菌-病毒动力学的基因组资源 | Ettinger, C. L. | N/A | A genomic resource for exploring bacterial-viral dynamics in seagrass ecosystems | |
| 化学基因组学揭示了鲍曼不动杆菌中抗生素和必需基因的功能 | Tran, J. S. | N/A | Chemical genomics informs antibiotic and essential gene function in Acinetobacter baumannii | |
| 宏基因组挖掘揭示了双链DNA病毒中的新型病毒组蛋白 | Liu, Y. | N/A | Metagenomic mining reveals novel viral histones in dsDNA viruses | |
| 使用声波液体处理器的两步扩增子PCR效率提升 | Benz, B. R. | N/A | Improved Efficiency of Two-Step Amplicon PCR Using an Acoustic Liquid Handler | |
| 体内检测未接受治疗和接受抗逆转录病毒治疗（ART）的HIV-1反义转录本 | Capoferri, A. A. | N/A | In vivo detection of HIV-1 antisense transcripts in untreated and ART-treated individuals | |
| EV-D68感染期间诱导的线粒体自噬体促进病毒的非裂解性释放 | Jassey, A. | N/A | Mitophagosomes induced during EV-D68 infection promote viral nonlytic release | |
| 滴灌通过重塑水稻根际微生物群落来抑制甲烷排放。 | Lau, K. J. X. | N/A | Drip irrigation suppresses methane emissions by reshaping the rhizosphere microbiomes in rice | |
| 利用放线菌的生物合成多样性：通过比较基因组和代谢分析发现独特的天然产物 | Kikuchi, Y. | N/A | Harnessing the Biosynthetic Diversity of Actinomycetes: Discovery of Unique Natural Products through Comparative Genomic and Metabolic Analysis | |
| 通过综合蛋白质组学方法探索病毒与宿主相互作用，发现BANF1是非洲猪瘟病毒的新关键因子。 | Dupre, J. | N/A | Exploring virus-host interactions through combined proteomic approaches identifies BANF1 as a new essential factor for African Swine Fever Virus. | |
| LEDGF/p75介导的整合中断会解除对HIV-1基因组反义转录的抑制 | Tedbury, P. R. | N/A | Disruption of LEDGF/p75-directed integration derepresses antisensetranscription of the HIV-1 genome | |
| 泛素样蛋白（UBLs）的蛋白质和小分子底物的全局分析 | Shao, G. | N/A | Global analysis of protein and small-molecule substrates of ubiquitin-like proteins (UBLs) | |
| 利用工程细胞分裂素调节剂可预测地调控植物根系发育 | Rattan, R. | N/A | Predictable modulation of plant root development using engineered cytokinin regulators | |
| 用于工程合成基因组模块和染色体的迭代SCRaMbLE | Lu, X. | N/A | Iterative SCRaMbLE for Engineering Synthetic Genome Modules and Chromosomes | |
| Vgamma1+ γδ T细胞衍生的IL-4启动CD8 T细胞免疫 | Le, S. | N/A | Vgamma1+ gammadelta T cell-derived IL-4 initiates CD8 T cell immunity | |
| 来得容易，去得更快：绘制整个生命树中鞭毛运动能力的丧失图谱 | Philip, J. S. | N/A | Easy come, easier go: mapping the loss of flagellar motility across the tree of life | |
| 培养及分子表征孕妇分娩前留置导尿管尿液、清洁中段尿及阴道拭子 | Greenberg, J. M. | N/A | Cultivation and molecular characterization of Foley catheterized urine, clean catch urine, and vaginal swabs from pregnant women prior to delivery | |
| 原生动物种群驱动瘤胃微生物组的系统性变异 | Kobel, C. M. | N/A | Protozoal populations drive system-wide variation in the rumen microbiome | |
| 肝素酶，一种强效抑制逆转录病毒转录的宿主基因 | Waxman, B. | N/A | Heparanase, a host gene that potently restricts retrovirus transcription | |
| 人类中siRNAs介导的基因沉默的结构基础 | Sarkar, S. | N/A | Structural basis for gene silencing by siRNAs in humans | |
| Chd1的CHCT结构域与Rtf1之间的直接相互作用控制着Chd1在活性基因上的分布以及核小体的定位。 | Tripplehorn, S. A. | N/A | A direct interaction between the Chd1 CHCT domain and Rtf1 controls Chd1 distribution and nucleosome positioning on active genes | |
| RNA介导的MYC多聚化抑制先天免疫信号传导 | Uhl, L. | N/A | RNA-mediated MYC multimerization suppresses innate immune signaling | |
| 资源防御在促进性选择武器进化中的作用：一项实验进化测试 | Audet, T. | N/A | The role of resource defensibility in facilitating sexually-selected weapon evolution: An experimental evolution test | |
| 印度不同地理区域埃及伊蚊种群中电压门控钠通道（VGSC）基因IIS6结构域的遗传多样性 | Sumitha, M. K. | N/A | Genetic diversity in the IIS6 domain of Voltage Gated Sodium Channel (VGSC) gene among Aedes aegypti populations from different geographical regions in India | |
| 人类肠道微生物组中氨基酸脱羧酶酶的多样性与普遍性——一项生物信息学研究 | Sandoval, M. | N/A | Diversity and prevalence of amino acid decarboxylase enzymes in the human gut microbiome -- a bioinformatics investigation | |
| 对库蠓属蚊虫（Culicoides sonorensis）进行的实验性BTV-3和BTV-8病毒感染 | Zeiske, S. | N/A | Experimental BTV-3 and BTV-8 infection of Culicoides sonorensis biting midges | |
| 酵母中依赖RNA的蛋白质的普查 | Waber, N. B. | N/A | A census of RNA-dependent proteins in yeast | |
| 评估用于归巢抑制基因驱动的目标基因 | Xu, X. | N/A | Assessing target genes for homing suppression gene drive | |
| 研究同多聚体儿茶酚1,2-双加氧酶的四级结构：一项综合结构生物学研究。 | Almeida-Juarez, A. G. | N/A | Investigating the quaternary structure of a homomultimeric catechol 1,2-dioxygenase: An integrative structural biology study. | |
| 通用节奏架构揭示了不同的神经动力学模式 | K, G. | N/A | Universal rhythmic architecture uncovers distinct modes of neural dynamics | |
| 振荡爆发特征与人类工作记忆期间偏差之间的关联 | Kavanaugh, B. | N/A | The association between oscillatory burst features and deviations during human working memory | |
| 意志调节与中脑振荡的可转移模式 | Lu, H.-Y. | N/A | Volitional Regulation and Transferable Patterns of Midbrain Oscillations | |
| 人类海马体在导航和心理模拟过程中低频振荡的异同 | Seger, S. | N/A | Differences and similarities between human hippocampal low-frequency oscillations during navigation and mental simulation | |
| 成年视觉剥夺会引发与丘脑皮质输入相关的突触前可塑性 | Murase, S. | N/A | Adult visual deprivation engages associative, presynaptic plasticity of thalamic input to cortex | |
| 在使用Cntnap2基因敲除的自闭症大鼠模型进行语音辨别任务时，使用预测提示 | Centanni, T. M. | N/A | Use of a predictor cue during a speech sound discrimination task in a Cntnap2 knockout rat model of autism | |
| 诚然夸张：吼猴的咆哮声是体型大小的可靠信号，并且对听者具有行为上的相关性。 | Dunn, J. C. | N/A | Honestly exaggerated: howler monkey roars are reliable signals of body size and behaviourally relevant to listeners | |
| 早产儿出生后，大脑发育呈现出异质性、时间一致性和可塑性。 | Thalhammer, M. | N/A | Heterogeneous, temporally consistent, and plastic brain development after preterm birth | |
| 观察言语：先天性聋和听力正常者在提示性言语感知中的神经机制 | Sarre, A. | N/A | Seeing speech: neural mechanisms of cued speech perception in prelingually deaf and hearing users | |
| 在认知控制下，大脑会根据需要选择性地将能量分配给功能性脑网络。 | Saberi, M. | N/A | The brain selectively allocates energy to functional brain networks under cognitive control | |
| # BioRxiv 2024-12-05 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 模拟西欧的欧亚猞猁种群：未来50年的前景如何？ | Bauduin, s. | N/A | Modelling Eurasian lynx populations in Western Europe: What prospects for the next 50 years? | |
| 利用Fisher核方法从脑动力学模型中准确可靠地预测个体特征 | Ahrends, C. | N/A | Predicting individual traits from models of brain dynamics accurately and reliably using the Fisher kernel | |
| Heron：一个直观的知识图谱编辑器，用于实现基于Python的实验流程。 | Dimitriadis, G. | N/A | Heron: A Knowledge Graph editor for intuitive implementation of python based experimental pipelines. | |
| 作为肺结核的辅助治疗药物——去铁胺 | Kaushik, S. R. | N/A | Deferoxamine as adjunct therapeutics for tuberculosis | |
| 产生相同M矩阵的替代突变架构可能导致不同的进化分歧模式 | Jiang, D. | N/A | Alternative mutational architectures producing identical M-matrices can lead to different patterns of evolutionary divergence | |
| 异质性突触稳态：一种提升皮层信息传播的新机制 | Razi, F. | N/A | Heterogeneous Synaptic Homeostasis: A Novel Mechanism Boosting Information Propagation in the Cortex | |
| 转座子活性在全基因组复制后塑造顺式调控元件进化中的作用 | Monsen, O. | N/A | The role of transposon activity in shaping cis-regulatory element evolution after whole genome duplication | |
| 皮质纹状体动作控制固有的对立认知动机风格 | Avila, C. | N/A | Cortico-striatal action control inherent of opponent cognitive-motivational styles | |
| 有效连接预测知觉决策信心、不确定性和速度的分布式神经编码 | Asadpour, A. | N/A | Effective connectivity predicts distributed neural coding of perceptual decision confidence, uncertainty and speed | |
| 球形表型聚类 | Nightingale, L. | N/A | Spherical Phenotype Clustering | |
| 多组织网络分析揭示JNK抑制对饮食蔗糖引起的大鼠代谢功能障碍的影响 | Mardinoglu, A. | N/A | Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats | |
| 病毒适应与致死性突变的瞬时进化流行病学 | Guillemet, M. | N/A | Transient evolutionary epidemiology of viral adaptation and lethal mutagenesis | |
| 深层组织空间组学：以高空间分辨率成像整个胚胎的转录组和亚细胞结构 | Gandin, V. | N/A | Deep-tissue spatial omics: imaging whole-embryo transcriptomics and subcellular structures at high spatial resolution | |
| Rtc调控的RNA修复机制模型提示了增强抗生素效果的分子靶点。 | Hindley, H. J. | N/A | A mechanistic model of Rtc-regulated RNA repair suggests molecular targets to potentiate antibiotic effects | |
| 整合代谢建模与成像技术用于筛选结直肠癌治疗靶点 | Tavakoli, N. | N/A | Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer | |
| 2022年初印度突破性感染血清针对保守的隐秘5类表位，以对抗SARS-CoV-2变种的免疫逃逸。 | Das Jana, I. | N/A | Early 2022 breakthrough infection sera from India target the conserved cryptic class 5 epitope to counteract immune escape by SARS-CoV-2 variants | |
| 通过深度突变扫描技术，解析MET受体酪氨酸激酶激酶结构域的耐药机制 | Estevam, G. O. | N/A | Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning | |
| 功能基因嵌入提高了罕见变异的复杂遗传风险评分 | Londhe, S. | N/A | Functional gene embeddings improve rare variant polygenic risk scores | |
| 细胞分化过程中基因表达的内在维度 | Biondo, M. | N/A | The intrinsic dimension of gene expression during cell differentiation | |
| 在猪链球菌发病机制中荚膜多糖的调节合成 | Wang, X. | N/A | Regulative synthesis of capsular polysaccharides in the pathogenesis of Streptococcus suis | |
| 钙从内质网向其他细胞器的转移在弓形虫中对最佳信号传导至关重要。 | Li, Z.-H. | N/A | Calcium transfer from the ER to other organelles for optimal signaling in Toxoplasma gondii. | |
| 在帕金森病中，运动方向快速逆转期间，丘脑底核-皮层同步性的情境依赖性调制 | Winkler, L. | N/A | Context-Dependent Modulations of Subthalamo-Cortical Synchronization during Rapid Reversals of Movement Direction in Parkinson's Disease | |
| 胸侧半切术后控制系带行走和分带行走时相持续时间的脊髓感觉运动回路的运作 | Rybak, I. A. | N/A | Operation of spinal sensorimotor circuits controlling phase durations during tied-belt and split-belt locomotion after a lateral thoracic hemisection | |
| 巴巴利猕猴社交信息的化学特征 | Weiss, B. M. | N/A | Chemical signatures of social information in Barbary macaques | |
| 农业集约化导致的遗传多样性丧失及有害突变暴露 | Nolen, Z. J. | N/A | Species-specific loss of genetic diversity and exposure of deleterious mutations following agricultural intensification | |
| 多站点研究中基于扩散磁共振成像的结构连接组的协调 | Shen, R. S. | N/A | Harmonization of Diffusion MRI-based Structural Connectomes for Multi-site Studies | |
| DeepPaint：一个用于细胞显像图像分类的深度学习工具包 | Luna, D. | N/A | DeepPaint: A deep-learning package for Cell Painting Image Classification | |
| 受体信号放大定量分析：全激动剂的Kd/EC50比值作为增益参数 | Buchwald, P. | N/A | Quantification of Signal Amplification for Receptors: The Kd/EC50 Ratio of Full Agonists as a Gain Parameter | |
| O-特异性抗原的丧失塑造了假单胞菌在小鼠临床前肺部感染模型中的微生物地理分布 | Fraser, H. | N/A | Loss of O-specific antigen shapes Pseudomonas aeruginosa microbiogeography in murine preclinical pulmonary infection model | |
| 在空间导航过程中，对决策神经动力学的全脑表征 | Haley, S. P. | N/A | Cortex-wide characterization of decision-making neural dynamics during spatial navigation | |
| 突破屏障：真菌毒素白念珠菌素在肠道芯片模型中破坏上皮完整性并诱发炎症 | Morelli, M. | N/A | Breaking barriers: the fungal toxin candidalysin disrupts epithelial integrity and induces inflammation in a gut-on-chip model | |
| 禾本科姐妹种的基因组揭示了草类出现之前的关键代谢创新 | Takeda-Kimura, Y. | N/A | Genomes of Poaceae sisters reveal key metabolic innovations preceding the emergence of grasses | |
| 4-甲基七叶皂苷（4-MU）可改善大鼠脑缺血/再灌注损伤后的学习和记忆能力。 | Tamouk, S. | N/A | 4-Methyllumifrone (4-MU) can improve learning and memory after cerebral ischemia/reperfusion injury in rats | |
| 耶氏解脂耶氏酵母中基因编码报告基因的总体评价 | Zhang, H. | N/A | General assessment of genetically-encoded reporters in Yarrowia lipolytica | |
| 多核巨细胞是卵巢衰老的标志，具有独特的免疫和降解相关分子特征。 | Converse, A. | N/A | Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures | |
| HIV-1蛋白编码序列存在于相关细菌中 | Pelaez-Prestel, H. F. | N/A | HIV-1 protein coding sequences are present in relevant bacteria | |
| 葡萄糖感应ChREBP蛋白在糖尿病视网膜病变发病机制中的作用 | Starr, C. R. | N/A | Glucose-Sensing ChREBP Protein in the Pathogenesis of Diabetic Retinopathy | |
| 从一位患有年轻型糖尿病10型（由杂合INS突变引起）的患者中衍生出的诱导多能干细胞系ERCi003-A的生成 | Bastrich, A. | N/A | Generation of an induced pluripotent stem cell line ERCi003-A derived from a patient with maturity-onset diabetes of the young type 10 caused by a heterozygous INS mutation | |
| 非经典Sun1-Allan复合体在快速有丝分裂期间调控核膜重塑和基体/微管组织中心分离 | Zeeshan, M. | N/A | Non canonical Sun1-Allan complex orchestrates nuclear envelope remodelling and Basal Body/MTOC Segregation during rapid mitosis in Plasmodium | |
| 一种新型SUN1-ALLAN复合物在恶性疟原虫快速闭合有丝分裂期间协调核膜两侧的双极中心粒分离 | Zeeshan, M. | N/A | A novel SUN1-ALLAN complex coordinates segregation of the bipartite MTOC across the nuclear envelope during rapid closed mitosis in Plasmodium | |
| 胞外HDAC6 ZnF UBP结构域增强足体介导的神经元迁移 | Qureshi, T. | N/A | Extracellular HDAC6 ZnF UBP domain enhances podosome-mediated neuronal migration | |
| 从一名年轻型糖尿病3型患者的皮肤成纤维细胞中生成了iPSC系ERCi004-A，该患者因HNF1A基因的杂合突变而患病。 | Bastrich, A. | N/A | Generation of iPSC line ERCi004-A from human dermal fibroblasts of a patient with maturity-onset diabetes of the young type 3 caused by a heterozygous mutation in the HNF1A gene | |
| 自闭症蛋白质在纤毛处的汇聚 | Kostyanovskaya, E. | N/A | Convergence of autism proteins at the cilium | |
| 自闭症蛋白在纤毛处的汇聚 | Kostyanovskaya, E. | N/A | Convergence of autism proteins at the cilium | |
| EOR-1/PLZF调控的WAH-1/AIF依次促进非凋亡性尸体清除的早期和晚期阶段 | Rather, N. | N/A | EOR-1/PLZF-regulated WAH-1/AIF sequentially promotes early and late stages of non-apoptotic corpse removal | |
| EOR-1/PLZF调控的WAH-1/AIF依次促进非凋亡性尸体清除的早期和晚期阶段 | Rather, N. | N/A | EOR-1/PLZF-regulated WAH-1/AIF sequentially promotes early and late stages of non-apoptotic corpse removal | |
| 缺血后处理的心脏保护作用是通过抑制RAP2C-MAP4K4通路介导的 | Zhang, M. | N/A | The Cardioprotective Effect of Ischemic Postconditioning is Mediated by Inhibiting RAP2C-MAP4K4 Pathway | |
| 抑制巨核细胞中RhoA介导的分泌性自噬可减轻小鼠的骨髓纤维化 | Becker, I. C. | N/A | Inhibition of RhoA-mediated secretory autophagy in megakaryocytes mitigates myelofibrosis in mice | |
| 热应激对卵巢、卵泡和卵母细胞的影响：系统综述 | Zhou, L. T. | N/A | The Effects of Heat Stress on the Ovary, Follicles and Oocytes: A Systematic Review | |
| CGC1，一种新的大肠杆菌参考基因组 | Ichikawa, K. | N/A | CGC1, a new reference genome for Caenorhabditis elegans | |
| 生物分子凝聚物通过可移动的锚定物促进膜润湿 | GrandPre, T. | N/A | Membrane wetting by biomolecular condensates is facilitated by mobile tethers | |
| AER-270和TGN-020不是水通道蛋白-4水通道阻断剂。 | Unger, L. | N/A | AER-270 and TGN-020 are not aquaporin-4 water channel blockers | |
| 肠道微生物群认知：我们对肠道微生物群了解多少？一项国际问卷调查。 | Garcia-Gutierrez, E. | N/A | Gut MicrobiotAware: how much do we know about gut microbiota? An international questionnaire. | |
| 隐孢子虫胞内生存所需的主机基因揭示了可用于治疗的代谢依赖性 | Marzook, N. B. | N/A | The essential host genome for Cryptosporidium intracellular survival exposes metabolic dependencies that can be leveraged for treatment | |
| 索莫莫浅井水中沙门氏菌的表征及其对肯尼亚埃尔多雷特莫里加·奥列费拉种子提取物的抗菌敏感性 | Cheronoh, J. | N/A | Characterization of Salmonella typhi from Shallow Well Water in Sogomo, Eldoret- Kenya and its Antimicrobial Sensitivity to Moringa oleifera Seed Extract | |
| CHD4与TBX5相互作用，以维持出生后心房肌细胞的基因调控网络 | Sweat, M. E. | N/A | CHD4 Interacts With TBX5 to Maintain the Gene Regulatory Network of Postnatal Atrial Cardiomyocytes | |
| 利用联合物种分布模型检测群落中的生态进化动力学 | Pantel, J. H. | N/A | Detection of eco-evolutionary dynamics in communities using Joint Species Distribution Models | |
| 芸苔属植物和其传粉者之间的相互作用受到蜜蜂群落管理和新烟碱类种子处理的影响。 | Nottebrock, H. | N/A | Interactions between Brassica carinata and its pollinators is shaped by managed beehives and neonicotinoid seed treatment | |
| 低投入土壤管理在提高产量和减少二氧化碳排放的同时，却加剧了气候变化下冬小麦种植系统中硝酸盐淋失和病害的风险。 | Michel, J. | N/A | Low-input soil management increases yield and decreases CO2-emissions but aggravates risk of nitrate leaching and diseases in winter wheat cropping systems under climate change | |
| 大陆边缘沉积物中甲烷循环古菌丰度、群落结构及分解代谢途径的驱动因素 | Deng, L. | N/A | Drivers of methane-cycling archaeal abundances, community structure, and catabolic pathways in continental margin sediments | |
| 小RNA调控与基因组和谐：对沼泽兰花（Dactylorhiza）异源多倍体进化的见解 | Eriksson, M. C. | N/A | Small RNAs regulation and genomic harmony: insights into allopolyploid evolution in marsh orchids (Dactylorhiza) | |
| 年龄和性激素对女性在整个成年期神经肌肉功能的影响 | O'Bryan, S. J. | N/A | The effect of age and sex hormones on female neuromuscular function across the adult lifespan | |
| 增强CAR-T细胞的狂犬病毒受限于I型干扰素和快速收缩 | Burchett, R. | N/A | Boosting of CAR-T cells with rhabdovirus is limited by type I interferon and rapid contraction | |
| 贝叶斯最小二乘超树（BLeSS）：灵活推断大型时间校准系统发育树 | Cerny, D. | N/A | Bayesian Least-Squares Supertrees (BLeSS): flexible inference of large time-calibrated phylogenies | |
| 基于有限元分析的股骨颈骨折固定生物力学评估 | Rao, L. | N/A | Biomechanical Evaluation of Femoral Neck Fracture Fixation Based on Finite Element Analysis | |
| 通过DECIPHER实现大规模异质空间组学的高保真解耦细胞嵌入 | Xia, C.-R. | N/A | High-fidelity disentangled cellular embeddings for large-scale heterogeneous spatial omics via DECIPHER | |
| 评估基于性别和种族的基因表达综合数据库（GEO）数据集中的多样性、公平性和包容性（DEI）偏见 | Gondal, M. N. | N/A | Assessing DEI Bias in Gene Expression Omnibus (GEO) Datasets Based on Gender and Ethnicity | |
| 脑肿瘤和黑色素瘤来源的细胞系对替莫唑胺的敏感性：与MGMT基因表达的关系 | Baguley, B. C. | N/A | Sensitivity to temozolomide of cell lines derived from brain tumours and melanomas: relationship to MGMT gene expression | |
| 巨胞饮作用调控代谢应激驱动的胰腺癌中癌症相关成纤维细胞亚型身份 | Zhang, Y. | N/A | Macropinocytosis controls metabolic stress-driven CAF subtype identity in pancreatic cancer | |
| 性别特异性见解：药物诱导的小鼠寿命延长与体重减轻 | Belikov, A. V. | N/A | Sex-specific insights into drug-induced lifespan extension and weight loss in mice | |
| 酒精会下调原肠胚基因表达和细胞运动，导致胎儿酒精谱系障碍的症状。 | Alsakran, A. A. | N/A | Ethanol down-regulates gastrula gene expression and cell movement, causing symptoms of foetal alcohol spectrum disorders | |
| 建模决策和反馈控制在变化环境中对生物体的利弊 | Kumar, R. | N/A | Modelling benefits and costs of decision making and feedback control for organisms in changing environments | |
| 系统生物学的通用微分方程：当前状态与开放问题 | Philipps, M. | N/A | Universal differential equations for systems biology: Current state and open problems | |
| 患者来源的PBMCs的体外扩增优先导致效应记忆T细胞的增殖，并恢复了HBV-HCC中的自体效率。 | Kah, J. | N/A | Ex-vivo expansion of patient-derived PBMCs preferentially results in effector memory T-cell proliferation with restored autologous efficiency in HBV-HCC | |
| 海洋青鳉对二噁英的反应与其近亲淡水青鳉（日本青鳉）有所不同：其AHR分子机制存在差异。 | Zhang, W. | N/A | Marine medaka responds differently to dioxin compared with its close freshwater relative, the Japanese medaka: the AHR molecular mechanism | |
| 揭示未特征化的NSP结构和功能意义以及在哺乳动物和非哺乳动物动脉病毒分子工具包中的变异 | Rakesh, S. | N/A | Uncovering the Structural and Functional Implications of Uncharacterized NSPs and Variations in the Molecular Toolkit Across Mammalian and Non-Mammalian Arteriviruses | |
| 识别潜在人群特征对风险因素的效应修饰作用：基于稀疏变化的系数回归 | Wang, R. | N/A | Identifying Effect Modification of Latent Population Characteristics on Risk Factors with a Sparse Varying Coefficient Regression | |
| 通过快速进化的免疫开关实现Argonaute的动态调控 | Ewe, C. K. | N/A | Dynamic Control of Argonautes by a Rapidly Evolving Immunological Switch | |
| 人类下肢活动信号提取与分类的肌音图研究 | Bai, Y. | N/A | An Investigation into Mechanomyography for Signal Extraction and Classification of Human Lower Limb Activity | |
| 使用量子退火进行多序列比对的可扩展引导树构建 | Park, Y. | N/A | Scalable Guide Tree Construction Using Quantum Annealing for Multiple Sequence Alignment | |
| 自动细胞类型注释与参考簇映射 | Galanti, V. | N/A | Automated Cell Type Annotation with Reference Cluster Mapping | |
| 使用预训练的Transformer模型预测肿瘤基因表达的组织来源 | Mellors, T. | N/A | Predicting Tissue of Origin from Bulk Tumor Gene Expression using a Pre-trained Transformer Model | |
| 用于分析单细胞分辨率相互作用的稀疏降维 | Brunn, N. | N/A | Sparse dimensionality reduction for analyzing single-cell-resolved interactions | |
| 本地单体型分类器能够实现高效、灵活且安全的基因型推断及下游分析 | Cheema, M. N. | N/A | Local Haplotype Classifiers enable Efficient, Flexible, and Secure Genotype Imputation and Downstream Analyses | |
| 通过利用外显子组测序数据中的脱靶读取，识别与基因组特征相关的新基因和表型关联 | Ercelen, D. | N/A | Identifying novel genetic and phenotypic associations to genomic features by leveraging off-target reads in exome sequencing data | |
| 氨基酸转移自由能揭示生物分子凝聚物形成的热力学驱动力 | Rekhi, S. | N/A | Amino Acid Transfer Free Energies Reveal Thermodynamic Driving Forces in Biomolecular Condensate Formation | |
| 移动肌球蛋白马达驱动的集群形成与相分离在运动实验中的作用 | Slater, B. | N/A | Cluster Formation and Phase Separation Driven by Mobile Myosin Motors in the Motility Assay | |
| 扩展质量（eQual）：基于n元相似性的径向阈值聚类 | Chen, L. | N/A | Extended Quality (eQual): Radial threshold clustering based on n-ary similarity | |
| α-突触核蛋白敲除损害了黑色素瘤的发展，并以性别依赖的方式改变了TG3小鼠模型中的DNA损伤修复 | Arnold, M. R. | N/A | Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner | |
| 皮肤人乳头瘤病毒E6损害cGAS-STING通路 | Tolbert, E. | N/A | Cutaneous human papillomavirus E6 impairs the cGAS-STING pathway | |
| 去甲基化药物对急性髓性白血病小鼠模型中白血病微环境基因调控及疾病进程的影响 | Ebelt, N. D. | N/A | Effects of Hypomethylating Agents on Gene Modulation in the Leukemic Microenvironment and Disease Trajectory in a Mouse Model of AML | |
| 多组学分析揭示了鼻咽鳞状细胞癌中的恶性亚群及缺氧驱动的血管生成轴作为治疗脆弱性 | You, C. | N/A | Multi-omic profiling identifies malignant subpopulations and a hypoxia-driven angiogenic axis as therapeutic vulnerabilities in sinonasal squamous cell carcinoma | |
| 腺病毒对IRE1α-XBP1信号通路的动态调控 | Jang, Y. | N/A | Dynamic modulation of IRE1α-XBP1 signaling by adenovirus | |
| 空间单细胞转录组分析揭示了一种新型DICER1综合征小鼠模型（GEMM）的细胞起源及其相关肉瘤的发展层次 | Kommoss, F. K. | N/A | Spatial single cell transcriptomic analysis of a novel DICER1 Syndrome GEMM informs the cellular origin and developmental hierarchy of associated sarcomas | |
| 脑老化过程中的微血管搏动及其在麻醉中的混杂效应 | Skott, M. V. | N/A | Microvascular pulsatility of the ageing brain and confounding effects of anaesthesia | |
| 在心脏收缩功能受损的患者中，左心室停滞是由血流输送而非射血分数决定的。 | Martinez-Legazpi, P. | N/A | Flow transport and not ejection fraction determines left ventricular stasis in patients with impaired systolic function | |
| 溪刺鱼（Culaea inconstans）栖息于中性及碱性湖泊中，其碱耐受性的种内差异 | Zimmer, A. M. | N/A | Intraspecific differences in alkaline tolerance in brook stickleback (Culaea inconstans) inhabiting neutral and alkaline lakes | |
| 研究慢性短睡眠对新陈代谢和氧化应激生存的影响 | Tener, S. J. | N/A | Investigating the consequences of chronic short sleep for metabolism and survival of oxidative stress | |
| 工蜂羽化后立即发生的代谢变化 | Verbinnen, G. | N/A | Shifts in honeybee worker metabolism immediately post-eclosion | |
| 通过生长辅助正反馈的超弹道细胞间信号传导 | Wang, M. | N/A | Hyperballistic intercellular signaling through growth assisted positive feedback | |
| 备忘录：一种微型备忘录传感器，利用精确的无细胞表达平台检测微RNA-RISC | Copeland, C. E. | N/A | MEMO: A Micro Memo Sensor Detecting microRNA-RISC using an Accurate Cell-Free Expression Platform | |
| RNA结合蛋白调控生发中心B细胞的G2-M检查点 | Salerno, F. | N/A | RNA-binding proteins control the G2-M checkpoint of the germinal centre B cell | |
| 协调数字化植物标本数据以增强生物多样性知识：为格陵兰植物区系创建更新清单。 | Whitley, B. S. | N/A | Harmonising digitised herbarium data to enhance biodiversity knowledge: creating an updated checklist for the flora of Greenland. | |
| 渔业监测还是鱼类监测？尽管存在保护危机，三文鱼产卵监测的减少仍在持续 | Atkinson, E. M. | N/A | Monitoring for fisheries or for fish? Declines in monitoring of salmon spawners continue despite a conservation crisis | |
| 高频鸣叫蟋蟀（Eneopterinae）前翅超微结构的比较研究 | ROYER, L. | N/A | Comparative forewing ultrastructure of high-frequency singing crickets (Eneopterinae) | |
| 即使在实际温度没有变化的情况下，对温度的感知也足以驱动跨代表观遗传的遗传。 | Teichman, G. | N/A | Perception of Temperature Even in the Absence of Actual Change is Sufficient to Drive Transgenerational Epigenetic Inheritance | |
| 人类真菌病原体新生隐球菌交配型位点编码的关键基因 | Bian, Z. | N/A | Essential genes encoded by the mating-type locus of the human fungal pathogen Cryptococcus neoformans | |
| 多维变量剂量分析（mVDA）是一种用于高通量绘制遗传相互作用的新方法。 | Sengupta, S. | N/A | Multidimensional variable dose analysis (mVDA) is a novel method for high-throughput mapping of genetic interactions | |
| 增强果蝇细胞遗传检测的方法 | Wang, Y. | N/A | Enhanced methods for genetic assays in Drosophila cells | |
| 一个解析谱系的多模态单细胞图谱揭示了早期秀丽隐杆线虫发育的基因组动力学 | van der Burght, S. N. | N/A | A lineage-resolved multimodal single-cell atlas reveals the genomic dynamics of early C. elegans development | |
| 一种用于在Cauloacter crescentus中高效快速进行基因组编辑的CRISPR/SpCas9M-报告系统 | Sun, J. | N/A | A CRISPR/SpCas9M-reporting system for efficient and rapid genome editing in Caulobacter crescentus | |
| 在蛋白质结构标记器中平衡局部性与重构性 | Meynard-Piganeau, B. | N/A | Balancing Locality and Reconstruction in Protein Structure Tokenizer | |
| CellSexID：基于性别的嵌合模型细胞起源计算追踪 | Tai, H. | N/A | CellSexID: Sex-Based Computational Tracking of Cellular Origins in Chimeric Models | |
| ProtSpace：一种用于可视化蛋白质空间的工具 | Senoner, T. | N/A | ProtSpace: a tool for visualizing protein space | |
| 一种从低覆盖率测序数据中进行常见变异基因分型的高效新算法 | Zhang, S. | N/A | A Novel Efficient Algorithm for Common Variants Genotyping from Low-Coverage Sequencing Data | |
| 准确的通用DNA表征在基因组基础模型的大规模应用中显现 | Ellington, C. N. | N/A | Accurate and General DNA Representations Emerge from Genome Foundation Models at Scale | |
| RNA-DNA和DNA-DNA相互作用组的联合分析揭示了它们之间的强关联性。 | Zvezdin, D. S. | N/A | Joint analysis of RNA-DNA and DNA-DNA interactomes reveals their strong association | |
| 人牛磺酸转运蛋白TauT的结构揭示了底物识别与抑制机制 | lu, Y. | N/A | Structure of the human taurine transporter TauT reveals substrate recognition and mechanisms of inhibition | |
| 将分子尺度与细胞尺度相结合，用于膜受体信号传导模型 | Peterson, K. J. | N/A | Bridging molecular to cellular scales for models of membrane receptor signaling | |
| DNA张力计揭示了驱动蛋白-1、-2和-3的捕获键解离动力学 | Noell, C. R. | N/A | DNA tensiometer reveals catch-bond detachment kinetics of kinesin-1, -2 and -3 | |
| 电压门控钙通道失调可能参与钙调蛋白病神经症状的发生 | Hussey, J. W. | N/A | Voltage Gated Calcium Channel Dysregulation May Contribute to Neurological Symptoms in Calmodulinopathies | |
| 力场极化对蛋白质集体运动的影响 | Milinski, A. | N/A | Impact of force field polarization on the collective motions of proteins | |
| 靶细胞张力调控巨噬细胞吞噬作用 | Cornell, C. E. | N/A | Target cell tension regulates macrophage trogocytosis | |
| IFNγ依赖的代谢重编程抑制了黑色素瘤中不成熟、促转移的淋巴状态。 | Karakousi, T. | N/A | IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma | |
| 解析由免疫系统控制的休眠转移的表型 | Chamorro, V. | N/A | Unraveling the Phenotype of Dormant Metastases Controlled by the Immune System | |
| 氧化还原催化亚基冗余性使N-糖基化的治疗靶向成为可能 | Baro, M. | N/A | OST Catalytic Subunit Redundancy Enables Therapeutic Targeting of N-Glycosylation | |
| 系统生物学引导的NF-κB和BCL2靶向克服了DLBCL中微环境介导的BH3模拟物耐药性。 | Vareli, A. | N/A | Systems biology-enabled targeting of NF-κB and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL. | |
| 源自患者的肝细胞癌（HCC）细胞再现了与原发性HCV相关肝癌的转录组特征。 | Kah, J. | N/A | Patient-derived HCC cells recapitulating the transcriptomic landscape of primary HCV-related liver cancer | |
| 大麻二酚促进细胞凋亡并下调致癌因子 | Greenwood, A. L. | N/A | Cannabidiol promotes apoptosis and downregulation of oncogenic factors | |
| 节食通过诱导持久的肠道菌群失调，使小鼠的摄食行为失调。 | Fouesnard, M. | N/A | Yo-yo dieting deregulates feeding behavior in mice via the induction of durable gut dysbiosis | |
| 哺乳至断奶过渡期间肠道上皮转录组变化的单细胞图谱 | Malonga, T. | N/A | A single-cell atlas of transcriptome changes in the intestinal epithelium at the suckling-to-weaning transition | |
| 在内在无序的转录激活域中，功能保守而氨基酸序列不保守 | LeBlanc, C. J. | N/A | Conservation of function without conservation of amino acid sequence in intrinsically disordered transcriptional activation domains | |
| 发现独立调控健康寿命和最大寿命的热力学控制变量 | Denisov, K. A. | N/A | Discovery of Thermodynamic Control Variables that Independently Regulate Healthspan and Maximum Lifespan | |
| 异常的eNK细胞在宫腔粘连患者中促进子宫内膜纤维化 | Zhou, Z. | N/A | Abnormal eNK cells contribute to endometrial fibrosis in intrauterine adhesions patients | |
| 细胞因子动态与氧化应激在宿主细胞中对耐药和敏感结核分枝杆菌分离株的刺激反应 | Kumar, K. | N/A | Cytokine Dynamics and Oxidative Stress in Host Cells Stimulated with Drug-Resistant and Sensitive Mycobacterium tuberculosis Isolates | |
| 人免疫系统人源化-DRAGA小鼠是一个有价值的研究新型HIV-1免疫疗法的模型。 | Pumtang-on, P. | N/A | Human-immune-system humanized-DRAGA mice are a valuable model to study novel immunotherapies for HIV-1 | |
| 多花紫藤凝集素通过与扎伊尔埃博拉病毒糖蛋白复合物上特定N-连接糖基化位点的相互作用，增强了病毒的进入过程。 | Duncan, J. D. | N/A | Wisteria floribunda agglutinin enhances Zaire ebolavirus entry through interactions at specific N-linked glycosylation sites on the virus glycoprotein complex | |
| 有颌脊椎动物（Gnathostomata）胃的进化：通过基因组损失的研究——来自无胃物种的发现 | Dann, J. B. | N/A | Evolution of the Jawed Vertebrate (Gnathostomata) Stomach through Gene Repertoire Loss: Findings from Agastric Species | |
| 热感受神经元通过调节生殖系转座子来控制遗传继承。 | Szanto, P. | N/A | Thermosensory neurons control genetic inheritance through regulation of germline transposons | |
| 三种入侵昆虫的基因组草图及转录组序列数据 | Lombaert, E. | N/A | Draft genome and transcriptomic sequence data of three invasive insect species | |
| 糖尿病预防计划研究中的糖尿病前期表型聚类 | Stroebel, B. M. | N/A | Prediabetes Phenotype Clusters in the Diabetes Prevention Program Study | |
| 时间通过CpG位点簇的甲基化变化进行编码 | Ochana, B.-L. | N/A | Time is encoded by methylation changes at clustered CpG sites | |
| 阿尔茨海默病中单细胞水平上性别和APOE基因型特异性转录变化的风貌 | Yu, G. | N/A | The Landscape of Sex- and APOE Genotype-Specific Transcriptional Changes in Alzheimer's Disease at the Single Cell Level | |
| 一种极简主义的二进制/数字方法，利用光学标记的tRNAs和多种羧肽酶进行大规模单分子蛋白质鉴定，并将其扩展到肽段测序。 | Sampath, G. | N/A | A minimalist binary/digital approach to large-scale single molecule protein identification with optically labeled tRNAs and multiple carboxypeptidases and its extension to peptide sequencing | |
| 可以使用耳内和耳周的脑电极来估计言语接受阈值。 | Borges, H. B. | N/A | The Speech Reception Threshold Can be Estimated Using EEG Electrodes In and Around the Ear | |
| 人诱导多能干细胞衍生的运动神经支配增强了使用桌面制造技术工程化的肌肉束的分化 | Santoso, J. W. | N/A | Human iPSC-derived motor neuron innervation enhances the differentiation of muscle bundles engineered with benchtop fabrication techniques | |
| abCAN：一种实用且新颖的注意力网络，用于预测突变抗体亲和力 | Gong, C. | N/A | abCAN: a Practical and Novel Attention Network for Predicting Mutant Antibody Affinity | |
| 负二项隐因子模型用于配对微生物组测序数据 | Kim, H. | N/A | A negative binomial latent factor model for paired microbiome sequencing data | |
| 缓解光谱学揭示了贝达喹啉在活体分枝杆菌中的作用机制 | Harrison, S. H. | N/A | Remission spectroscopy resolves the mode of action of bedaquiline within living mycobacteria | |
| Q/R编辑和选择性过滤器突变对GluA2 AMPA受体钙通透性原子机制的调节 | Heiser, F. | N/A | Atomistic Mechanisms of Calcium Permeation Modulated by Q/R Editing and Selectivity Filter Mutations in GluA2 AMPA Receptors | |
| 通过细胞外基质（ECM）进行的机械通信依赖于频率，这是由于细胞对机械信号形状的敏感性所致。 | Nitsan, I. | N/A | Mechanical communication through the ECM is frequency-dependent due to cell sensitivity to mechanical signal shape | |
| 蛋白质-蛋白质界面中的挫败感在PROTAC三元复合物的协同作用中起着核心作用 | Ma, N. | N/A | Frustration in the Protein-Protein interface Plays a Central Role in the Cooperativity of PROTAC Ternary Complexes | |
| 堂娜·弗洛尔和她的两个丈夫：发现新型HDAC6/AKT2抑制剂用于髓系癌症治疗 | Waitman, K. B. | N/A | Dona Flor and her two husbands: Discovery of novel HDAC6/AKT2 inhibitors for myeloid cancer treatment | |
| 对立谱系调控因子诱导肺腺癌中的促肿瘤混合身份状态 | Fort, G. | N/A | Opposing lineage specifiers induce a pro-tumor hybrid-identity state in lung adenocarcinoma | |
| MOZ和HBO1组蛋白乙酰转移酶复合物是NUP98重排急性髓系白血病的分子依赖性和治疗靶点 | Mullighan, C. G. | N/A | MOZ and HBO1 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia | |
| 环状RNA - circCLIP2主要在胶质母细胞瘤干细胞（GSC）微环境中表达，并通过上皮间质转化（EMT）和细胞外基质（ECM）信号传导途径增强胶质母细胞瘤的侵袭性。 | Misiorek, J. O. | N/A | Circular RNA - circCLIP2 is predominantly expressed in GSC niche and enhances glioblastoma aggressiveness via EMT and ECM signaling | |
| Gankyrin/PSMD10下调影响胶质母细胞瘤中癌细胞的生长和增殖：体外和体内研究 | Travnikova, D. | N/A | Downregulation of Gankyrin/PSMD10 affects cancer cell growth and proliferation in glioblastoma: in vitro and in vivo study | |
| 通过超快化学蛋白质组学研究Pt(IV)与氯尼达明配体的作用机制 | Imaikina, E. A.. | N/A | Study on the mechanism of action of the Pt(IV) complex with lonidamine ligands by ultrafast chemical proteomics | |
| 表型分析隐藏的一半：结合无人机表型分析和机器学习预测田间大麦根系性状 | Alahmad, S. | N/A | Phenotyping the hidden half: Combining UAV phenotyping and machine learning to predict barley root traits in the field | |
| 探究DI-DII连接子在Nav1.5通道功能中的作用 | Wagner, E. | N/A | Investigating the Functional Role of the DI-DII Linker in Nav1.5 Channel Function | |
| 在棕色脂肪细胞特异性缺失ATGL和HSL的情况下，非颤抖性产热功能保持完整，这可能是由于白色脂肪组织的棕色化作用。 | Manandhar, Y. | N/A | Non-shivering thermogenesis is intact upon brown-adipocyte specific loss of ATGL and HSL due to white adipose tissue browning | |
| 外周人多形核白细胞激活和吞噬作用的高维光谱流式细胞术分析 | Lamb, E. R. | N/A | High-dimensional spectral flow cytometry of activation and phagocytosis by peripheral human polymorphonuclear leukocytes | |
| CD226+ 脂肪组织巨噬细胞源自MDP衍生的单核细胞，并调节脂质代谢。 | Gallerand, A. | N/A | CD226+ adipose tissue macrophages arise from MDP-derived monocytes and regulate lipid metabolism. | |
| 单倍二倍性加速昆虫线粒体基因组进化 | Pakrashi, A. | N/A | HAPLODIPOIDY ACCELERATES MITOGENOME EVOLUTION IN INSECTS | |
| SynapseNet：深度学习在自动突触重建中的应用 | Muth, S. | N/A | SynapseNet: Deep Learning for Automatic Synapse Reconstruction | |
| 负电荷基团在抗菌阳离子肽模拟物中的作用：对膜相互作用的深入理解 | Saiba, R. | N/A | The Role of Negatively Charged Groups in Antimicrobial Cationic Peptide Mimics: Insights into Membrane Interactions | |
| 语言复杂性在听觉和言语刺激神经处理中的时间性和半球动态变化：一项MEG源空间研究 | Krauss, P. | N/A | Temporal and Hemispheric Dynamics in Neural Processing of Auditory and Speech Stimuli Across Linguistic Complexity: A MEG Source Space Study | |
| 利用结合的脑电图（EEG）和脑磁图（MEG）测量分析人类大脑中处理名词和动词的差异 | Koelbl, N. | N/A | Analyzing Differences in Processing Nouns and Verbs in the Human Brain using Combined EEG and MEG Measurements | |
| GET3B与类囊体ALB3和ALB4插入酶相互作用，并参与叶绿体生物发生的初始阶段。 | Bodensohn, U. | N/A | GET3B interacts with the thylakoidal ALB3 and ALB4 insertases and is involved in the initial stages of chloroplast biogenesis | |
| 通过hTERT使间充质基质细胞永生化，不会影响分泌的外泌体的功能特性。 | Brancolini, A. | N/A | Immortalization of mesenchymal stromal cells by hTERT does not affect the functional properties of secreted extracellular vesicles | |
| CENcyclopedia：细胞周期中着丝粒结构的动态景观 | Chen, Y.-C. | N/A | CENcyclopedia: Dynamic Landscape of Kinetochore Architecture Throughout the Cell Cycle | |
| TMEM251对GNPTAB调控的分子洞察 | Yang, X. | N/A | Molecular Insights into the Regulation of GNPTAB by TMEM251 | |
| 冲突的时间线：探索四足动物分歧估计中线粒体-核不一致的模式 | Ranganathan, E. | N/A | Conflicting Timelines: Exploring patterns of mito-nuclear discordance in divergence estimates among tetrapods | |
| 用于脊髓损伤治疗的植入式3D打印多通道微通道 | Grebenyuk, S. | N/A | Implantable 3D printed multiplexed microtunnels for spinal cord injury treatment | |
| 研究成纤维细胞靠近肿瘤对其胞外囊泡生成的影响，利用3D生物打印的基质模型 | Amens, J. N. | N/A | Investigating the impact of fibroblast proximity to a tumor on fibroblast extracellular vesicle production utilizing 3D bioprinted stromal models | |
| 用于免疫防御创伤性脑损伤的疫苗 | Acharya, A. P. | N/A | Vaccines for immunological defense against traumatic brain injury | |
| 用于检测HG002 Genome In A Bottle NIST参考材料中低频变异体的稳健基准。 | Daniels, C. | N/A | A robust benchmark for detecting low-frequency variants in the HG002 Genome In A Bottle NIST reference material. | |
| CoLaML：从异质基因内容中推断潜在的进化模式 | Yamanouchi, S. | N/A | CoLaML: Inferring latent evolutionary modes from heterogeneous gene content | |
| 用于蛋白质结构预测的检索增强蛋白质语言模型 | Li, P. | N/A | Retrieval Augmented Protein Language Models for Protein Structure Prediction | |
| 使用机器学习预测小分子抗菌药物类别特异性 | Gadiya, Y. | N/A | Predicting antimicrobial class specificity of small molecules using machine learning | |
| GAPDH的RNA结合调控急性髓系白血病中转录本的稳定性和蛋白质翻译 | Imig, J. | N/A | RNA Binding of GAPDH Controls Transcript Stability and Protein Translation in Acute Myeloid Leukemia | |
| 多灶性小肠神经内分泌肿瘤的表观遗传学研究揭示了肿瘤加速老化及代谢基因的表观遗传学改变 | Webster, A. P. | N/A | Epigenetic investigation of multifocal small intestinal neuroendocrine tumours reveals accelerated ageing of tumours and epigenetic alteration of metabolic genes | |
| 在离体猪角膜感染模型中，使用管道环稳定地局部应用抗菌药物 | Foulkes, D. M. | N/A | Stable topical application of antimicrobials using plumbing rings in an ex vivo porcine corneal infection model | |
| 心肌梗死后11β羟基类固醇脱氢酶1型药理学抑制作用靶向外基质加工，并在小型猪模型中保护心脏功能 | Al Disi, S. | N/A | Pharmacological inhibition of 11βhydroxysteroid dehydrogenase type 1 after myocardial infarction targets extracellular matrix processing and preserves cardiac function in a translational mini-pig model | |
| ROSLT：一种改进的树莓派开源实时自愿轮跑追踪方法和资源 | Sanosa, P. | N/A | ROSLT: An Improved Raspberry-Pi Open-Source Live Voluntary-Wheel Running Tracker Method and Resource | |
| DoRIAT：一种用于解释和注释对接运行的贝叶斯框架。 | Maniatis, C. | N/A | DoRIAT: A Bayesian Framework For Interpreting And Annotating Docking Runs. | |
| 利用Immunemap这一开放的活体显微镜图谱，对免疫细胞运动进行系统分析 | Pizzagalli, D. U. | N/A | Systematic analysis of immune cell motility leveraging Immunemap, an open intravital microscopy atlas | |
| 巴西跳蚤科（半翅目：瘿蚜总科：瘿蚜科）中的Paurocephalini族跳蚤 | Serbina, L. | N/A | Jumping plant-lice of the tribe Paurocephalini (Hemiptera: Psylloidea: Liviidae) in Brazil | |
| 果蝇大脑中已鉴定神经元的突触图谱分析 | Wu, H. | N/A | Synapse profiling of identified neurons in the Drosophila brain | |
| 章鱼胺信号协调果蝇蘑菇体内突触前机制的空间模式 | Wu, H. | N/A | Octopamine signals coordinate the spatial pattern of presynaptic machineries in the Drosophila mushroom bodies | |
| 新诊断类风湿性关节炎患者和健康当前吸烟者对照组支气管肺泡灌洗细胞HLA-DR免疫肽组学的特征 | Zohrer, B. | N/A | Characterization of HLA-DR immunopeptidome of bronchoalveolar lavage cells in patients with newly diagnosed rheumatoid arthritis and healthy current-smoker controls | |
| 设计多型登革病毒疫苗：一种基于计算机的方法实现广谱免疫 | Singh, A. | N/A | Designing a multi-serotype Dengue virus vaccine: an in silico approach to broad-spectrum immunity | |
| 揭示分层淡水湖中军团菌的生态：季节动态、宿主相互作用及在氧气有限条件下的持久性 | Bergman, O. | N/A | Unveiling the Ecology of Legionella in a Stratified Freshwater Lake: Seasonal Dynamics, Host Interactions, and Persistence Under Oxygen Limited Conditions | |
| 被忽视的捕食性昆虫在濒危沿海栖息地中触发了潜在的关键生物多样性区域 | Ascenzi, A. | N/A | Neglected predatory insects trigger potential Key Biodiversity Areas in threatened coastal habitats | |
| 海胆花属（Penstemon）中具人形花的独特形态基础及其平行演化历史 | Depatie, T. H. | N/A | The unique morphological basis and parallel evolutionary history of personate flowers in Penstemon | |
| 基于系统发育的方法在灵长类动物中探索突变过程 | Kitch, J. C. | N/A | A Phylogeny-Based Approach to Discover Mutational Processes in Primates | |
| 形态上不同的群体是否对应于生殖隔离的物种？瑞士红蚁的一个案例研究 | Lavanchy, G. | N/A | Do morphologically distinct groups correspond to reproductively isolated species? A case study in Myrmica ants from Switzerland | |
| 揭示甜菜驯化和育种中的关键基因 | Dhiman, A. S. | N/A | Uncovering Genes Essential in Domestication and Breeding of Sugar Beet | |
| 基于Cas9的富集用于靶向长读段元条形码分析 | Nikolaeva-Reynolds, L. | N/A | Cas9-based enrichment for targeted long-read metabarcoding | |
| ERGA-BGE 参考基因组：来自伊比利亚干旱地区的特有鞭蛛 | Lozano-Fernandez, J. | N/A | ERGA-BGE Reference Genome of Gluvia dorsalis: An Endemic Sun Spider from Iberian Arid Regions | |
| RpiBeh：一种多用途的开源解决方案，用于实时追踪和基于行为的小鼠神经行为学闭环干预 | Sun, Y. | N/A | RpiBeh: a multi-purpose open-source solution for real-time tracking and behavior-driven closed-loop interventions in rodent neuroethology | |
| 从仅包含序列的训练数据生成全原子蛋白质结构 | Lu, A. X. | N/A | Generating All-Atom Protein Structure from Sequence-Only Training Data | |
| TROP2/Claudin程序介导免疫排斥，阻碍乳腺癌中的检查点阻断 | Wu, B. | N/A | A TROP2/Claudin Program Mediates Immune Exclusion to Impede Checkpoint Blockade in Breast Cancer | |
| 适应性复制原点激活改变了癌细胞中的染色质动力学和稳定性 | Perez-Venteo, A. | N/A | Adaptive replication origin activation alters chromatin dynamics and stability in cancer cells | |
| 泛素连接酶ITCH调控SARS-CoV-2病毒的生命周期 | Xiang, Q. | N/A | Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus | |
| 胶囊和遗传背景，而非特定基因座，对肺炎球菌生长动力学有强烈影响。 | Chaguza, C. | N/A | The capsule and genetic background, rather than specific loci, strongly influence pneumococcal growth kinetics | |
| 痘病毒编码的E3样蛋白的差异可以决定痘病毒激活细胞坏死性凋亡 | Enow, J. A. | N/A | Divergence in poxvirus-encoded E3-like proteins can dictate poxvirus activation of cellular necroptosis | |
| 对来自Mastomys natalensis的三种巨细胞病毒的分子克隆及宿主范围分析 | Staliunaite, L. | N/A | Molecular cloning and host range analysis of three cytomegaloviruses from Mastomys natalensis | |
| DynaMAP：通过高密度光学图谱进行动态微生物组丰度分析 | Abakumov, S. | N/A | DynaMAP: Dynamic Microbiome Abundance Profiling through high density optical mapping | |
| 全基因组序列、代谢谱分析及功能研究揭示，Ligilactobacillus salivarius LS-ARS2是一种具有显著抗氧化、抗菌及抗生物膜潜能的生物膜形成型益生菌，显示出良好的应用前景。 | Patra, S. | N/A | Complete Genome Sequence, Metabolic Profiling and Functional Studies reveal Ligilactobacillus salivarius LS-ARS2 is a Promising Biofilm-forming Probiotic with Significant Antioxidant, Antibacterial, and Antibiofilm Potential | |
| 有袋类动物肠道微生物组的宏基因组分析为低甲烷经济提供了遗传基础。 | Bowerman, K. L. | N/A | Metagenomic analysis of marsupial gut microbiomes provides a genetic basis for the low methane economy | |
| 肠道微生物群物种Levilactobacillus brevis调节秀丽隐杆线虫的生殖适应性 | Braun, N. J. | N/A | Gut microbiome species Levilactobacillus brevis regulates reproductive fitness in C. elegans | |
| 对原噬菌体激活的进化响应减弱了可培养的蚜虫内共生菌Serratia symbiotica相关菌株的毒力。 | VanDieren, A. J. | N/A | Evolution in response to prophage activation attenuates the virulence of culturable Serratia symbiotica relatives of aphid endosymbionts | |
| 实验性噬菌体进化导致对多重耐药和广泛耐药肺炎克雷伯菌分离株的宿主范围扩大 | Ghatbale, P. | N/A | Experimental Phage Evolution Results in Expanded Host Ranges Against MDR and XDR Klebsiella pneumoniae Isolates | |
| 优化人源单克隆抗体以增强对SARS-CoV-2的中和作用 | Wang, Q. | N/A | Optimizing a Human Monoclonal Antibody for Better Neutralization of SARS-CoV-2 | |
| E-box独立染色质招募使MYOD转变为转录抑制因子 | Nicoletti, C. | N/A | E-box independent chromatin recruitment turns MYOD into a transcriptional repressor | |
| 高通量表观遗传学分析免疫检测法，助力加速疾病研究和临床开发 | Van den Ackerveken, P. | N/A | High-Throughput Epigenetic Profiling Immunoassays for Accelerated Disease Research and Clinical Development | |
| 工程化一种受炭疽毒素启发的蛋白质-配体，用于纳米颗粒介导的恶性黑色素瘤治疗 | Marquez-Lopez, A. | N/A | Engineering an Anthrax Toxin inspired protein-ligand for Nanoparticle-Mediated Treatment of Malignant Melanoma | |
| 超过一半的注释人类miRNAs在表达水平上不足以执行其生物学功能。 | Kachooei, S. A. | N/A | More than half of annotated human miRNAs are never expressed at levels sufficient for biological function | |
| Rad52通过一个大的C端85残基片段作为装配陪伴蛋白来形成和稳定Rad51纤维 | Ma, E. | N/A | Rad52 Acts as an Assembly Chaperone to Form and Stabilize Rad51 Filaments Through a Large C-Terminus 85-Residue Segment | |
| Prp16能够高效剪接富含短内含子的隐球菌转录组中具有多样外显子一致性元件的内含子。 | Negi, M. S. | N/A | Prp16 enables efficient splicing of introns with diverse exonic consensus elements in the short-intron rich Cryptococcus neoformans transcriptome | |
| 高通量定量miRNA-3'-非翻译区调控效应 | Ding, Y. | N/A | High-Throughput Quantification of miRNA-3'-Untranslated-Region Regulatory Effects | |
| 使用斑马鱼hand2 Cre和CreERT2重组酶的CRISPR敲入进行谱系标记 | Ming, Z. | N/A | Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock-ins | |
| 药理浓度的维生素C能抑制髓过氧化物酶产生的次氯酸，而氧化态的维生素C则能抑制关键的硫醇蛋白并抑制Jurkat细胞的生长。 | Peskin, A. V. | N/A | Pharmacological concentrations of vitamin C inhibit hypochlorous acid generation by myeloperoxidase, and oxidized vitamin C inhibits critical thiol proteins and growth of Jurkat cells | |
| Tau中天冬氨酸的异常快速异构化 | Shoff, T. A. | N/A | Unusually Rapid Isomerization of Aspartic Acid in Tau | |
| 噼啪云：一种基于事件驱动的云端CRISPR-Cas9引导RNA设计工具 | Bradford, J. | N/A | Crackling Cloud: an event-driven, cloud-based CRISPR-Cas9 guide RNA design tool | |
| 可扩展的深度生成学习模拟蛋白质平衡系综 | Lewis, S. | N/A | Scalable emulation of protein equilibrium ensembles with generative deep learning | |
| 全面网络分析miRNA生物发生蛋白及其配体相互作用位点以识别癌症治疗的新靶点 | Almhanna, H. | N/A | Comprehensive Network Analysis of miRNA Biogenesis Proteins and Their Ligand Interaction Sites to Identify Novel Targets for Cancer Therapeutics | |
| 铜绿假单胞菌PA14鞭毛介导的表面感应的遗传分析 | Kuchma, S. | N/A | Genetic Analysis of Flagellar-Mediated Surface Sensing by Pseudomonas aeruginosa PA14 | |
| 缺乏多种氨基酸转运蛋白的酿酒酵母菌株的特性分析与全基因组测序：研究氨基酸转运的工具 | Sonawala, U. | N/A | Characterization and whole genome sequencing of Saccharomyces cerevisiae strains lacking several amino acid transporters: tools for studying amino acid transport | |
| 抗VCAM-1抗体的分离与表征揭示了Ig样结构域2和3在细胞间相互作用中的潜在作用 | Perera, B. | N/A | Isolation and Characterization of Antibodies Against VCAM-1 Reveals Putative Role for Ig-like Domains 2 and 3 in Cell-to-Cell Interaction | |
| CTP结合基序对S. coelicolor ParB与DNA、染色体分离及孢子形成菌丝生长的相互作用的重要性。 | Szymczak, J. | N/A | Significance of the CTP-binding motif for the interactions of S. coelicolor ParB with DNA, chromosome segregation and sporogenic hyphal growth. | |
| 冷冻电镜显示，源自心脏IGLV6的AL纤维可以具有多态性。 | Bassett, P. T. | N/A | Cryo-EM reveals that cardiac IGLV6-derived AL fibrils can be polymorphic | |
| 高通量分化人类血管类器官揭示脑静脉畸形蛋白的重叠与独特功能 | Skowronek, D. | N/A | High-throughput differentiation of human blood vessel organoids reveals overlapping and distinct functions of the cerebral cavernous malformation proteins | |
| 针对基因剪接的靶向阻断可能会扰乱内含子嵌入的微小RNA的调控。 | Ali, M. H. | N/A | Targeted blocking of gene splicing can dysregulate intron-embedded microRNAs | |
| # BioRxiv 2024-12-04 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 解密老年听众在噪声环境下的受损语音可懂度：耳蜗突触病变的作用 | Garrett, M. | N/A | Deciphering compromised speech-in-noise intelligibility in older listeners: the role of cochlear synaptopathy | |
| 惰性原发性皮肤B细胞淋巴瘤类似于持续的抗原反应，没有分化不良的迹象。 | Griss, J. | N/A | Indolent primary cutaneous B-cell lymphomas resemble persistent antigen reactions without signs of dedifferentiation | |
| 淀粉样蛋白β诱导脂滴介导的阿尔茨海默病中微胶质细胞功能障碍 | Prakash, P. | N/A | Amyloid beta Induces Lipid Droplet-Mediated Microglial Dysfunction in Alzheimer's Disease | |
| 小鼠皮层培养中微型兴奋性突触后电流的稳态突触可塑性需要神经元Rab3A。 | Koesters, A. G. | N/A | Homeostatic Synaptic Plasticity of Miniature Excitatory Postsynaptic Currents in Mouse Cortical Cultures Requires Neuronal Rab3A. | |
| DeepCristae是一种用于修复活体显微镜图像中线粒体嵴的卷积神经网络。 | Papereux, S. | N/A | DeepCristae, a CNN for the restoration of mitochondria cristae in live microscopy images | |
| 视觉工作记忆的稀疏空间支架 | Liu, B. | N/A | Sparse spatial scaffolding for visual working memory | |
| ZC3H11A突变通过触发PI3K-AKT和NF-κB介导的信号通路，导致人类和小鼠的高度近视。 | Chen, C. | N/A | ZC3H11A mutations cause high myopia by triggering PI3K-AKT and NF-κB mediated signaling pathway in humans and mice | |
| 数据转换和模型选择对微生物组分类数据特征重要性的影响 | Org, E. | N/A | Effects of Data Transformation and Model Selection on Feature Importance in Microbiome Classification Data | |
| 圈养与野生鼩鼱大脑基因表达的比较揭示了圈养的影响 | Bedoya Duque, M. A. | N/A | Gene expression comparisons between captive and wild shrew brains reveal captivity effects | |
| 将结核病基因组学引入临床：一个全面的流程，用于从基因组数据预测抗菌药物敏感性，经过ISO标准验证和认证。 | Horan, K. | N/A | Bringing TB genomics to the clinic: A comprehensive pipeline to predict antimicrobial susceptibility from genomic data, validated and accredited to ISO standards. | |
| 肠道病毒71通过激活储存操纵性钙离子通道和线粒体呼吸作用，对高效病毒复制至关重要。 | Hsu, B.-Y. | N/A | Activation of Store-Operated Calcium Entry and Mitochondiral Respiration by Enterovirus 71 Is Essential for Efficient Virus Replication | |
| 内体-溶酶体器组装（ELYSA）结构通过哺乳动物卵母细胞到胚胎的转变协调溶酶体降解系统。 | Satouh, Y. | N/A | Endosomal-lysosomal organellar assembly (ELYSA) structures coordinate lysosomal degradation systems through mammalian oocyte-to-embryo transition | |
| 听觉刺激通过调节阿尔法波段的振荡，延长了视觉整合的时间窗口。 | Xu, M. | N/A | Auditory stimuli extend the temporal window of visual integration by modulating alpha-band oscillations | |
| 利用机制性序列信息提升蛋白质表达模型的泛化能力 | Shen, Y. | N/A | Improving the generalization of protein expression models with mechanistic sequence information | |
| 拟南芥对波动光的感知 | Belmonte, A. | N/A | Sensory perception of fluctuating light in Arabidopsis | |
| Tribus：从多重成像和蛋白质组数据中半自动化发现细胞身份和表型 | Kang, Z. | N/A | Tribus: Semi-automated discovery of cell identities and phenotypes from multiplexed imaging and proteomicdata | |
| 辅助感觉运动扰动影响已学习的神经表征 | Rajeswaran, P. | N/A | Assistive sensory-motor perturbations influence learned neural representations | |
| 简单的壳体测量并不能一致地预测龟类的栖息地：对Lichtig和Lucas（2017）的回应 | Evers, S. W. | N/A | Simple shell measurements do not consistently predict habitat in turtles: a reply to Lichtig and Lucas (2017) | |
| 一种营养依赖型的天蓝色链霉菌觅食表型表现出增强的抗菌活性，并在该属中普遍存在。 | Soderholm, N. | N/A | A nutrient-dependent foraging phenotype of S. coelicolor exhibits enhanced antimicrobial activity and is common across the genus | |
| SLC13A2转运的柠檬酸是PKM2乙酰化和降解的代谢信号，以抑制肿瘤生长。 | Xiong, J. | N/A | SLC13A2-transported citrate is a metabolic signal for PKM2 acetylation and degradation to suppress tumor growth | |
| COEXIST：协调的单细胞级联多重组织图像整合 | Heussner, R. T. | N/A | COEXIST: Coordinated single-cell integration of serial multiplexed tissue images | |
| 多种毒素表现出与烟碱型乙酰胆碱受体的共同结合模式 | Do, H. N. | N/A | Diverse toxins exhibit a common binding mode to the Nicotinic Acetylcholine Receptors | |
| 惊悚的听觉刺激通过加强，而非改变时间，加速了反射性选择伸手任务中的快速视觉运动反应。 | Weerdesteyn, V. | N/A | Startling acoustic stimuli hasten reflexive choice reaching tasks by strengthening, but not changing the timing of, express visuomotor responses | |
| 聚（烯丙胺）/三聚磷酸盐纳米复合凝聚物作为疫苗开发中依赖NLRP3的系统性佐剂 | Rizzo, G. P. | N/A | Poly(allylamine)/tripolyphosphate nanocomplex coacervate as a NLRP3-dependent systemic adjuvant for vaccine development | |
| 利用计算机化飞行磨机研究栎树相关郭公甲科（鞘翅目：郭公甲科）飞行性能的种内和种间变异 | Le Souchu, E. | N/A | Intra- and interspecific variations in flight performance of oak-associated Agrilinae (Coleoptera: Buprestidae) using computerised flight mills | |
| 内感受信号在猕猴的决策过程中产生偏差 | Cardenas, M. A. | N/A | Interoceptive Signals Bias Decision Making in Rhesus Macaques | |
| 重复的外源性和各向异性机械输入促进极化黏着连接的延长 | Yang, X. | N/A | Repeated extrinsic and anisotropic mechanical inputs promote polarized adherens junction elongation | |
| 转录组分析揭示了依赖DLK的海马谷氨酸能神经元退化的细胞网络 | Ritchie, E. M. | N/A | Translatome analysis reveals cellular network in DLK-dependent hippocampal glutamatergic neuron degeneration | |
| 膜结合B细胞受体组装的动态与激活 | Do, H. N. | N/A | Dynamics and Activation of Membrane-Bound B Cell Receptor Assembly | |
| 杜氏肌营养不良症中的肌肉干细胞表现出分子损伤和细胞命运轨迹的改变，影响其再生能力。 | Granet, J. A. | N/A | Muscle stem cells in Duchenne muscular dystrophy exhibit molecular impairments and altered cell fate trajectories impacting regenerative capacity | |
| 鞘氨醇-1-磷酸信号通路调控穆勒胶质细胞转变为具有神经发生能力的增殖性前体样细胞的能力 | Taylor, O. | N/A | Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells | |
| 交联琼脂糖-明胶珠作为研究细菌病原体生物膜的基质 | Roizman, D. | N/A | Cross-linked agarose-gelatine beads as a substrate for investigating biofilms of bacterial pathogens | |
| 药物性CDK4/6抑制剂促进衰老相关的溶酶体改变，并增强乳腺癌对溶酶体增效剂的敏感性 | Nehme, J. | N/A | Pharmacological CDK4/6 inhibitors promote senescence-associated lysosomal alterations and enhance sensitivity to lysosomotropic agents in breast cancer | |
| FishPi：一种生物信息学预测工具，用于在斑马鱼中关联piRNA和转座元件 | Godden, A. M. | N/A | FishPi: a bioinformatic prediction tool to link piRNA and transposable elements in zebrafish | |
| 陆地植物中依赖光的细胞核重新定位的开始 | Iwabuchi, K. | N/A | The beginnings of light-dependent nuclear relocation in land plants | |
| 片足动物分泌细胞类型与摄食、先天免疫及行为调控相关 | Mayorova, T. D. | N/A | Placozoan secretory cell types implicated in feeding, innate immunity and regulation of behavior | |
| 空间多组学与SpaMosaic的马赛克整合 | Yan, X. | N/A | Mosaic integration of spatial multi-omics with SpaMosaic | |
| STRUCT：一种从原始测序数据中识别RNA二级结构的统计方法，无需进行多序列比对 | Wang, J. F. | N/A | STRUCT: a statistical approach to identify RNA secondary structures from raw sequencing data, bypassing multiple sequence alignment | |
| 提高生成化学中分子字符串表示的可靠性 | Reboul, E. | N/A | Improving the reliability of molecular string representations for generative chemistry | |
| 小麦白粉菌效应蛋白与杀伤蛋白UmV-KP4和UmV-KP6结构相关，对真菌具有毒性，并在真菌中定义了扩展的蛋白质家族。 | de Guillen, K. | N/A | Zymoseptoria tritici effectors structurally related to killer proteins UmV-KP4 and UmV-KP6 are toxic to fungi, and define extended protein families in fungi | |
| 通过同时进行转录起始位点映射和甲基化定量来解码m6Am | Liu, J. F. | N/A | Decoding m6Am by simultaneous transcription-start mapping and methylation quantification | |
| 感觉运动整合增强了温度刺激处理 | Anderson, L. S. | N/A | Sensorimotor integration enhances temperature stimulus processing | |
| 通过恢复衰老的骨祖细胞来促进骨修复 | Reeves, J. | N/A | Rejuvenating aged osteoprogenitors for bone repair | |
| 在曲霉菌感染期间，IFN-STAT1-CYBB轴定义了保护性的浆细胞样DC与中性粒细胞之间的交叉对话。 | Guo, Y. | N/A | An IFN-STAT1-CYBB Axis Defines Protective Plasmacytoid DC to Neutrophil Crosstalk During Aspergillus fumigatus Infection. | |
| 组蛋白乙酰转移酶p300对RORβ的乙酰化以及SIRT1的去乙酰化作用，调控受体的稳定性、周转率及转录活性。 | O'Leary, T. R. | N/A | Acetylation of RORβ by histone acetyltransferase p300 and deacetylation by SIRT1 modulates receptor stability, turnover and transcriptional activity. | |
| TXNIP通过介导LAT1/SLC7A5的内吞作用，减少进入静止状态的细胞对氨基酸的摄取。 | Kahlhofer, J. | N/A | TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence | |
| 几何扭曲在陷入棒状突触中减缓了谷氨酸的扩散并塑造了突触反应：来自解剖学上现实的蒙特卡罗模拟的见解 | Thoreson, W. B. | N/A | Geometric tortuosity at invaginating rod synapses slows glutamate diffusion and shapes synaptic responses: insights from anatomically realistic Monte Carlo simulations | |
| 微生物裂解物作为细胞农业培养基配方中的低成本血清代用品 | Dolgin, J. | N/A | Microbial lysates as low-cost serum replacements in cellular agriculture media formulation | |
| 岛屿人口结构：哥特兰标志性金雕的繁殖动态及其驱动因素 | Singh, N. J. | N/A | Island population demography: Breeding dynamics and drivers of Gotland's iconic Golden Eagles | |
| 不同年龄段在噪音环境下的语音感知：蒙古沙鼠与人类的比较研究 | Jüchter, C. | N/A | Speech-in-noise perception across the lifespan: A comparative study in Mongolian gerbils and humans | |
| 具有自体组织驻留巨噬细胞的人类心脏类器官再现了生理性免疫-心脏相互作用 | O'Hern, C. | N/A | Human heart assembloids with autologous tissue-resident macrophages recreate physiological immuno-cardiac interactions | |
| 一份关于真实植物来源的胞外囊泡的可靠参考标记物及其系统发育保守程度的纲要 | Rodriguez de Lope, M. M. | N/A | A compendium of bona fide reference markers for genuine plant-derived extracellular vesicles and their degree of phylogenetic conservation | |
| 研究在光系统II中形成Tyr |
Boussac, A. | N/A | Investigation of electrochromic band-shifts in the Soret region induced by the formation of Tyr |
|
| 叶酸可预防草原田鼠因发育期接触拟除虫菊酯而导致的自闭症相关表型。 | Saferin, N. | N/A | Folate prevents the autism-related phenotype caused by developmental pyrethroid exposure in prairie voles | |
| 通过长程连接在皮层区域之间建立动态共识 | Javadzadeh, M. | N/A | Dynamic consensus-building between neocortical areas via long-range connections | |
| 鉴定出一种由SARS-CoV2 S2蛋白衍生、具有超抗原样T细胞刺激特性的肽段 | Tu, T. H. | N/A | The identification of a SARs-CoV2 S2 protein-derived peptide with super-antigen-like stimulatory properties on T-cells | |
| 遗传性出血性毛细血管扩张症2/Alk1在动脉内皮中的缺失导致鼻出血和脑微出血，伴有异常动脉和缺陷的平滑肌覆盖 | Zhang, X. | N/A | Arterial endothelial deletion of hereditary hemorrhagic telangiectasia 2/Alk1 causes epistaxis and cerebral microhemorrhage with aberrant arteries and defective smooth muscle coverage | |
| 基因组中转换突变频率高于颠换突变的证据：基于密度泛函理论计算碱基对结合能的结果 | Deka, N. | N/A | Higher frequency of transition mutation over transversion mutation in genomes: evidence from the binding energy calculation of base pairs using DFT | |
| 4-甲基龙胆醇（4-MU）可改善大鼠脑缺血/再灌注损伤后的学习和记忆能力。 | Tamouk, S. | N/A | 4-Methyllumifrone (4-MU) can improve learning and memory after cerebral ischemia/reperfusion injury in rats | |
| 高级肽纳米颗粒能够实现基因编辑器在多种细胞类型中强效且高效的递送。 | Gustafsson, O. | N/A | Advanced Peptide Nanoparticles Enable Robust and Efficient delivery of gene editors across cell types | |
| 一个评分统治一切：利用GWAS汇总统计数据进行正则化集合多基因风险预测 | Zhao, Z. | N/A | One score to rule them all: regularized ensemble polygenic risk prediction with GWAS summary statistics | |
| 犬持续性苗勒管综合征：对AMH和AMHR2基因组织的新见解 | Krzeminska, P. | N/A | Persistent Mullerian duct syndrome in dogs: a new insight into organization of AMH and AMHR2 genes | |
| 重塑乳腺癌肝转移局部治疗格局：一种新型瘤内p21靶向经皮疗法提高BALB/c小鼠接种4T1三阴性乳腺癌细胞后的生存率。 | Margulies, B. S. | N/A | Reshaping the Landscape of Locoregional Treatments for Breast Cancer Liver Metastases: A novel, intratumoral, p21-targeted percutaneous therapy increases survival in BALB/c mice inoculated with 4T1 triple negative breast cancer cells in the liver. | |
| 使用12-6 Lennard-Jones势能模型模拟银(I)离子与蛋白质的相互作用：一种自下而上的参数化方法 | Manciocchi, L. | N/A | Modelling the interaction between silver(I) ion and proteins with the 12-6 Lennard-Jones potential: a bottom-up parameterization approach | |
| 海藻糖促进埃及伊蚊细胞的生长，并调控基因表达和登革病毒复制。 | Marten, A. D. | N/A | Trehalose supports the growth of Aedes aegypti cells and modifies gene expression and dengue virus replication | |
| 通过结合显式的交联信息来改进AlphaFold 3的结构建模 | Kosinski, J. | N/A | Improving AlphaFold 3 structural modeling by incorporating explicit crosslinks | |
| 在专科神经精神病诊所中，血浆pTau181水平升高与阿片类药物使用相关，并在临床相关的时间尺度上指导药物剂量调整。 | Hanson, E. | N/A | Elevated plasma pTau181 in a specialty neuropsychiatric clinic is associated with opioid use and guides medication titration on a clinically relevant short-time scale | |
| 呼吸阶段调节与视觉刺激相关的任务神经表征 | Stetza, L. | N/A | The respiratory phase modulates task-related neural representations of visual stimuli | |
| 超越刺激起始：在自由观看过程中，物体内的持续注视不会重新唤起类别表征。 | Auerbach-Asch, C. R. | N/A | Beyond stimulus onset: Ongoing fixations within an object do not re-evoke category representations during free-viewing. | |
| 情感内容影响视觉工作记忆的精确度 | Haghian, Z. | N/A | Emotional content effects the precision of visual working memory | |
| 用于果蝇活体内单细胞标记和操控的稀疏驱动系统 | Xu, C. | N/A | The sparse driver system for in vivo single-cell labeling and manipulation in Drosophila | |
| 颞叶癫痫主要表现为区域特异性的发作间期皮层抑制 | Kienitz, R. | N/A | Temporal Lobe Epilepsy is dominated by Region Specific Interictal Cortical Inhibition | |
| 在韩国，小刺猬（Crocidura lasiura）中检测并描述了琅琊病毒 | Natasha, A. | N/A | Detection and characterization of Langya virus in Crocidura lasiura, Republic of Korea | |
| 在韩国，检测并鉴定出朗格雅病毒存在于灰麝鼩（Crocidura lasiura）中。 | Natasha, A. | N/A | Detection and characterization of Langya virus in Crocidura lasiura, Republic of Korea | |
| 逆转录转座子LINE1的反式调控分化过程维持胚胎干细胞特性 | Ren, L. | N/A | Retrotransposon LINE1 trans-regulatory differentiation process maintain embryonic stem cell identity | |
| 人类细胞中基因低表达和高表达的形态图 | Chandrasekaran, S. N. | N/A | Morphological map of under- and over-expression of genes in human cells | |
| NJGPT：一种由大型语言模型驱动、用户友好的系统发育树构建解决方案 | Wang, Z. | N/A | NJGPT: A Large Language Model-Driven, User-Friendly Solution for Phylogenetic Tree Construction | |
| 通过微喷雾器的通道增加功能活性——对时间分辨冷冻电镜活性测定的影响 | Garg, P. | N/A | Passage through micro-sprayer increases functional activity-implications for activity assays in time-resolved cryo-EM | |
| 缺氧诱导因子驱动透明细胞肾癌中miRNA介导的L2HGDH和HIF1A下调，与14q缺失无关 | Seal, S. | N/A | Hypoxia inducible factors drive miRNA-mediated downregulation of L2HGDH and HIF1A in clear cell renal cancer independent of 14q deletion | |
| 时间配置作为声音的新特征：心理和神经生理学证据，跨物种一致性及潜在的神经机制 | Zhai, Y. | N/A | Temporal Configuration as a New Feature of Sound: Psychological and Neurophysiological Evidence, Cross-species Consistency and Underlying Neuronal Mechanisms | |
| 强迫性倾向个体在概率学习及更新预测表征中的个体差异 | Brezoczki, B. | N/A | Individual differences in probabilistic learning and updating predictive representations in individuals with obsessive-compulsive tendencies | |
| 中国女性阴道微生态与炎症的关系研究。 | Zhang, Y. | N/A | Vaginal Microbiome and Inflammation Among Chinese Women. | |
| Tabula Sapiens揭示了28种人体器官和组织中细胞类型的转录因子表达、衰老效应和性别特异性特征。 | The Tabula Sapiens Consortium, | N/A | Tabula Sapiens reveals transcription factor expression, senescence effects, and sex-specific features in cell types from 28 human organs and tissues | |
| 在诱导多能干细胞衍生的疾病模型中扩展GABA能神经元的多样性 | Hu, R. | N/A | Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models | |
| 从微观到宏观：鸟类染色体进化主要受自然选择驱动 | Alfieri, J. M. | N/A | From Micro to Macro: Avian Chromosome Evolution is Dominated by Natural Selection | |
| 在听觉处理动物模型中描述早期生活压力的行为效应 | Hardy, K. A. | N/A | Characterizing Behavioral Effects of Early-Life Stress in an Animal Model of Auditory Processing | |
| 普遍的言语节奏规律：语调单元形成低频节奏，并平衡跨语言的音节率变异性。 | Inbar, M. | N/A | A universal of speech timing: Intonation units form low frequency rhythms and balance cross-linguistic syllable rate variability | |
| 平等群体中的社会补丁觅食理论 | Blum Moyse, L. | N/A | Social patch foraging theory in an egalitarian group | |
| 基于基因共表达网络的间充质干细胞分析揭示了异位骨化的关键基因和分子通路 | Yang, M. | N/A | A gene co-expression network-based analysis of mesenchymal stromal cells reveals novel genes and molecular pathways underlying heterotopic ossification | |
| 在津巴布韦利用替代传粉者提高生物多样性和小农户收入 | Allebone-Webb, S. | N/A | Farming with Alternative Pollinators for Increased Biodiversity and Smallholder Incomes in Zimbabwe | |
| 最佳实践质量光度法：单分子质量测量的优化指南 | Kratochvil, J. | N/A | Best practice mass photometry: A guide to optimal single molecule mass measurement | |
| 植物对特定环境条件的电生理反应 | Wilkening, S. H. P. | N/A | Plant electrophysiological reactions to specific environmental conditions | |
| 组蛋白H3.3中单个氨基酸突变揭示了H3K4甲基化在植物中的功能意义 | Xue, M. | N/A | Single amino acid mutations in histone H3.3 illuminate the functional significance of H3K4 methylation in plants | |
| 比较早熟、高产及育种潜力方面的籽粒类型和菜用大豆性状 | Saha, M. | N/A | Comparing grain type and vegetable soybean traits for early maturity, higher yield, and breeding potential | |
| 比较谷物类型和蔬菜大豆的早熟性、高产性和育种潜力 | Saha, M. | N/A | Comparing grain type and vegetable soybean traits for early maturity, higher yield, and breeding potential | |
| 面向AI抗干扰的核酸合成订单筛查：流程、结果与建议 | Wittmann, B. J. | N/A | Toward AI-Resilient Screening of Nucleic Acid Synthesis Orders: Process, Results, and Recommendations | |
| 使用tACS对α和β频率神经节律进行研究，探讨其对相位对齐的TMS诱发的皮层脊髓兴奋性的影响 | Gialopsou, A. | N/A | An investigation of the effects of α and β-frequency neural entrainment using tACS on phase-aligned TMS-evoked corticospinal excitability | |
| Anapc5和Anapc7作为KIF18A功能在生育力和有丝分裂进程中的遗传修饰因子 | Nesbit, C. | N/A | Anapc5 and Anapc7 as genetic modifiers of KIF18A function in fertility and mitotic progression | |
| 探索线粒体-核相互作用在调控细胞生理中的作用：来自种间细胞质杂种的启示 | Gaertner, K. | N/A | Exploring mitonuclear interactions in the regulation of cell physiology: insights from interspecies cybrids | |
| 小胶质细胞经历趋化因子受体CX3CR1介导的胞外Tau内吞作用。 | Chidambaram, H. | N/A | Microglia undergoes chemokine receptor, CX3CR1-mediated internalization of extracellular Tau | |
| 溶酶体功能、应激抵抗和修复受损是由于表达亚历山大病GFAP R239C突变体所致。 | Hernandez-Gerez, E. | N/A | Lysosomal function, resistance to stress and repair are compromised by expression of the Alexander disease GFAP R239C mutant | |
| 通过E3连接酶TRIM21诱导的化学介导的核孔复合体蛋白降解 | LI, X. | N/A | Chemically Induced Nuclear Pore Complex Protein Degradation via E3 Ligase TRIM21 | |
| PHLPP2是一种假磷酸酶，在多细胞生物的祖先中失去了活性。 | Husremovic, T. | N/A | PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor | |
| PHLPP2是一种假磷酸酶，在多细胞生物的祖先中失去了活性。 | Husremovic, T. | N/A | PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor | |
| Pirin 不与 p65 结合，也不调节 NFκB 依赖的基因表达。 | Meschkewitz, M. | N/A | Pirin does not bind to p65 or regulate NFkappaB-dependent gene expression | |
| mRNArchitect：mRNA序列的优化设计 | Budzinska, M. A. | N/A | mRNArchitect: optimized design of mRNA sequences | |
| 力场参数、实验测量与分子动力学模拟的综合数据库 | Banas, P. | N/A | Integrated Database of Force-Field Parameters, Experimental Measurements and Molecular Dynamics Simulations | |
| 一种计算进化发育生物学方法，用于阐明PLETHORA转录因子在调控根系发育中的作用 | Rodriguez-Herrera, J. | N/A | A computational Evo-Devo approach for elucidating the roles of PLETHORA transcription factors in regulating root development | |
| MpANT-生长素环调节地钱发育 | Dipp-Alvarez, M. | N/A | The MpANT-auxin loop modulates Marchantia polymorpha development | |
| 组蛋白H2A及其变体H2A.Z和H2A.W在拟南芥中的结构与功能相互关系 | Wang, Y. | N/A | Structural and functional interrelationship of histone H2A and its variants H2A.Z and H2A.W in Arabidopsis | |
| 在拟南芥中，细胞质中的光呼吸乙醛酸旁路在高光条件下支持光合作用和植物生长。 | Jiang, X. | N/A | A photorespiratory glyoxylate shunt in the cytosol supports photosynthesis and plant growth under high light conditions in Arabidopsis | |
| 驯化是否以牺牲耐压性为代价来促进叶片生长？对八个早熟禾亚科草种的证据进行搜索 | Yun, J. | N/A | Does domestication trade-off stress tolerance for leaf growth? A search for evidence across eight Pooideae grass species | |
| 一种与RdDM相关的雌性特异性元件指导水稻配子体发育过程中的从头DNA甲基化 | Kim, T. | N/A | A female-specific RdDM-associated element guides de novo DNA methylation during rice gametophyte development | |
| 分泌途径运输维持拟南芥减数分裂期间纺锤体分离的细胞器带 | JIANG, H. | N/A | Secretory trafficking maintains the organelle band for spindle separation during Arabidopsis meiosis | |
| 分泌运输在拟南芥减数分裂期间维持着丝粒分离的细胞器带。 | Piskorz, E. W. | N/A | Secretory trafficking maintains the organelle band for spindle separation during Arabidopsis meiosis | |
| 多核巨细胞是卵巢衰老的标志，具有独特的免疫和降解相关分子特征。 | Converse, A. | N/A | Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures | |
| 多核巨细胞是卵巢衰老的标志，具有独特的免疫和降解相关分子特征。 | Converse, A. | N/A | Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures | |
| Tmbim5 缺失导致斑马鱼肌肉萎缩，但不会加剧 mcu 或 slc8b1 敲除的表型 | Wasilewska, I. | N/A | Tmbim5 loss causes muscle atrophy in zebrafish without exacerbating mcu or slc8b1 knockout phenotypes | |
| 通过高内涵成像在人类破骨细胞中鉴定抗吸收GPCR | Price, M. L. | N/A | Identification of anti-resorptive GPCRs by high-content imaging in human osteoclasts | |
| 利用集成明场和荧光显微镜的组织学引导单细胞质谱成像 | Potthoff, A. | N/A | Histology-Guided Single-Cell Mass Spectrometry Imaging using Integrated Bright-field and Fluorescence Microscopy | |
| 利用分离信息进行变异过滤可提高向日葵（Helianthus annuus L.）花蜜生产基因的定位 | Barstow, A. C. | N/A | Variant filters using segregation information improve mapping of nectar-production genes in sunflower (Helianthus annuus L.) | |
| 常见的菌根网络介导的植物间信号能够调节植物对生物胁迫的响应以及对叶部病原体的防御 | Orlovskis, Z. | N/A | Common mycelial network mediated inter-plant signals modulate plant biotic stress responses and defence against foliar pathogens | |
| 指纹图谱和化学型分析方法揭示了野生啤酒花（Humulus lupulus L.）之间广泛的遗传和代谢多样性。 | Ducrocq, F. | N/A | Fingerprinting and chemotyping approaches reveal a wide genetic and metabolic diversity among wild hops (Humulus lupulus L.) | |
| 一种综合方法用于分析蝙蝠对人类病原体的抗体反应 | Toshkova, N. | N/A | An integrative approach for profiling antibody responses in bats to human pathogens | |
| 纤毛门锥虫属布鲁氏锥虫中Sec13同源基因的多功能作用 | Sharif, M. | N/A | Multifunctional Roles of Sec13 Paralogues in the Euglenozoan Trypanosoma brucei | |
| α-突触核蛋白纤维的结构多态性改变了Hsc70介导的解聚途径 | Jager, S. | N/A | Structural polymorphism of alpha-synuclein fibrils alters pathway of Hsc70 mediated disaggregation | |
| α-突触核蛋白纤维的结构多态性改变了Hsc70介导的解聚途径 | Jager, S. | N/A | Structural polymorphism of alpha-synuclein fibrils alters pathway of Hsc70 mediated disaggregation | |
| α-突触核蛋白纤维的结构多态性改变了Hsc70介导的解聚途径 | Jaeger, S. | N/A | Structural polymorphism of alpha-synuclein fibrils alters pathway of Hsc70 mediated disaggregation | |
| 基于CBAM-ResNet34的温室草莓发育过程分类与评估方法 | Wang, J. | N/A | CBAM-ResNet34-based classification and evaluation method for developmental processes of greenhouse strawberries | |
| 霉菌生长和户外暴露对肯尼亚西部诱人目标糖饵效力的影响。 | Yalla, n. O. | N/A | Influence of mould growth and outdoor exposure on the efficacy of attractive targeted sugar baits in western kenya. | |
| 短暂光刺激小鼠手部引发的皮层动力学：手/前肢S1和M1区的反应 | Pina Novo, D. | N/A | Cortical dynamics in hand/forelimb S1 and M1 evoked by brief photostimulation of the mouses hand | |
| Galectin-9与树突状细胞中的HLA-DR结合，调控免疫突触的形成和T细胞的增殖。 | Rodgers Furones, A. | N/A | Galectin-9 binding to HLA-DR in dendritic cells controls immune synapse formation and T cell proliferation | |
| 疫苗接种和感染会引发两种不同的人类长期记忆B细胞群体。 | Perugino, C. | N/A | Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection | |
| 哺乳动物的SKI复合体是一种广谱抗病毒药物靶点，它通过上调细胞胆固醇水平来抑制病毒复制。 | Weston, S. | N/A | The mammalian SKI complex is a broad-spectrum antiviral drug target that upregulates cellular cholesterol to inhibit viral replication | |
| 解析毛癣菌属（Trichophyton mentagrophytes）复合体内的系统发育关系：基于RADseq基因组的方法对“特比萘芬耐药”的Trichophyton indotineae作为独立物种的地位提出质疑 | Svarcova, M. | N/A | Resolving phylogenetic relationships within the Trichophyton mentagrophytes complex: a RADseq genomic approach challenges status of "terbinafine-resistant" Trichophyton indotineae as distinct species | |
| 硫磺岛高二氧化碳海洋环境中珊瑚礁共生体群落的变迁 | Huerlimann, R. | N/A | Shifts in Coral Reef Holobiont Communities in the High-CO2 Marine Environment of Iotorishima Island | |
| 睫状体尖端中心粒的结构揭示了微管接缝结合蛋白SPEF1的独特作用 | Legal, T. | N/A | Structure of the ciliary tip central pair reveals the unique role of the microtubule-seam binding protein SPEF1 | |
| VEXAS贫血是一种镶嵌性红细胞生成减少症。 | Rodrigues, F. | N/A | VEXAS anemia is a mosaic erythroblastopenia | |
| 面向光谱变异分析：非目标方法的数据质量框架 | Nichani, K. | N/A | Towards Spectral Variation Analysis: A Data Quality Framework for Non-Targeted Methods | |
| 对来自异质性患者来源的GBM干细胞模型进行全面的药理学调查 | Elliott, R. J. | N/A | A comprehensive pharmacological survey across heterogeneous patient-derived GBM stem cell models | |
| 依赖于己糖激酶1的植物非生物胁迫免疫取决于叶绿体定位 | Bagshaw, S. B. | N/A | Hexokinase 1-mediated plant immunity under abiotic stress depends on chloroplast positioning | |
| CrGEF1、CrGAP1 和 CrGDI2 作为调节 ROP-GTPase 介导的长春花中生物碱生物合成调控的关键因子。 | Sharma, A. | N/A | CrGEF1, CrGAP1, and CrGDI2 function as key regulators of ROP-GTPase mediated modulation of alkaloid biosynthesis in Catharanthus roseus | |
| 产品中立性功能定义的基因相互作用源于细胞生长机制模型。 | Fuentes Valenzuela, L. | N/A | The Product neutrality function defining genetic interactions emerges from mechanistic models of cell growth | |
| ALDH3A1介导的活性醛类解毒作用对去神经化与肌萎缩侧索硬化症进展中的不同肌肉反应有贡献 | Li, A. | N/A | ALDH3A1-mediated detoxification of reactive aldehydes contributes to distinct muscle responses to denervation and Amyotrophic Lateral Sclerosis progression | |
| 跨越上皮-间质转化（EMT）景观的过渡路径受网络逻辑支配。 | Dey, A. | N/A | Transition paths across the EMT landscape are dictated by network logic | |
| 语言网络揭示了由基于域的单词组成的蛋白质句子的语法约束 | Shimpi, A. A. | N/A | Linguistic networks uncover grammatical constraints of protein sentences comprised by domain-based words | |
| 受调控的资源再分配在酵母应激反应中是转录上硬连线的 | Kocik, R. A. | N/A | Regulated resource reallocation is transcriptionally hard wired into the yeast stress response | |
| 使用单细胞和空间转录组学数据识别替代多聚腺苷酸化工具的指南 | Zhao, Q. | N/A | Guidelines for alternative polyadenylation identification tools using single-cell and spatial transcriptomics data | |
| 诱导B细胞受体多样性预测PD-1阻断免疫疗法反应。 | Che, Y. | N/A | Induced B-Cell Receptor Diversity Predicts PD-1 Blockade Immunotherapy Response. | |
| 小热休克蛋白1（HSPB1）的协同进化受到α-晶体蛋白结构域与无序区域之间相互作用的促进 | Racigh, V. | N/A | Coevolution in Small Heat Shock Protein 1 (HSPB1) is Promoted by Interactions between the Alpha-Crystallin Domain and the Disordered Regions | |
| 双功能变二烯合酶的结构提供了对生物合成二萜装配和环化机制的独特见解。 | Wenger, E. S. | N/A | Structure of Bifunctional Variediene Synthase Yields Unique Insight on Biosynthetic Diterpene Assembly and Cyclization | |
| 绘制人类蛋白质组中隐秘磷酸化位点的图谱 | Gasparotto, D. | N/A | Mapping Cryptic Phosphorylation Sites in the Human Proteome | |
| 变异刺突蛋白动力学驱动SARS-CoV-2的免疫逃逸 | Ugurlu, H. | N/A | Altered spike dynamics drives immune evasion of SARS-CoV-2 | |
| 实验性猴痘病毒感染在大鼠中的研究 | Rockx, B. | N/A | Experimental monkeypox virus infection in rats | |
| 施马伦贝格病毒的非结构蛋白NSs和NSm对于库蠓属的索诺兰库蠓进行实验性感染并非必需。 | Wernike, K. | N/A | Schmallenberg virus non-structural proteins NSs and NSm are not essential for experimental infection of Culicoides sonorensis biting midges | |
| 在C3HeB/FeJ小鼠的隐性新型隐球菌感染过程中，肺部肉芽肿的形成经历了三个免疫学阶段。 | Betancourt, J. J. | N/A | Pulmonary granuloma formation during latent Cryptococcus neoformans infection in C3HeB/FeJ mice involves progression through three immunological phases | |
| 在缺乏亲缘识别的情况下，嵌合体的聚集多细胞性 | Weltzer, M. L. | N/A | Chimeric aggregative multicellularity in absence of kin discrimination | |
| HIV-1单个转录起始位点突变体展现出互补的复制功能，这些功能可以通过回复突变得以恢复。 | GC, K. | N/A | HIV-1 single transcription start site mutants display complementary replication functions that are restored by reversion | |
| 一种鉴定新生隐球菌敲除文库保真性的方法 | Jacobs, E. | N/A | A method for authenticating the fidelity of Cryptococcus neoformans knockout collections | |
| 一种新型白色念珠菌蛋白，受交配信号通路调控，塑造了物种间相互作用 | Parnandi, V. A. | N/A | A novel Candida glabrata protein regulated by mating signaling pathway shapes inter-species interaction | |
| 结核分枝杆菌痰液直接测序的方案和产率：系统综述与荟萃分析 | Mann, B. C. | N/A | Systematic review and meta-analysis of protocols and yield of direct from sputum sequencing of Mycobacterium tuberculosis | |
| 深度突变扫描（DMS）的CHIKV E3/E2病毒库映射了病毒氨基酸偏好，并预测了中和CHIKV抗体的病毒逃逸突变体。 | Stumpf, M. M. | N/A | Deep mutationally scanned (DMS) CHIKV E3/E2 virus library maps viral amino acid preferences and predicts viral escape mutants of neutralizing CHIKV antibodies | |
| 乌苏图病毒非洲3.1系，葡萄牙，2021-2023年 | Queiros, J. | N/A | Usutu virus African 3.1 lineage, Portugal, 2021-2023 | |
| 在复制压力的进出之间：基于PCNA/RPA1的动态调控同一细胞中的复制叉停滞与重启 | Dyankova-Danovska, T. K. | N/A | In and out of replication stress: PCNA/RPA1-based dynamics of fork stalling and restart in the same cell | |
| 高分辨率成像与三维视网膜色素上皮层结构解析 | Donaldson, K. J. | N/A | High resolution imaging and interpretation of three-dimensional RPE sheet structure | |
| PTX3调控成纤维细胞-上皮细胞动力学在肺损伤与修复中的作用 | Bammert, M.-T. | N/A | PTX3 Governs Fibroblast-Epithelial Dynamics in Lung Injury and Repair | |
| 高通量发现与深入表征细胞周期蛋白-CDK结合基序 | Ord, M. | N/A | High-throughput discovery and deep characterization of cyclin-CDK docking motifs | |
| PTTG1介导的周细胞功能障碍驱动糖尿病诱导的微血管功能障碍 | Zhang, L. | N/A | PTTG1-Mediated Pericyte Dysfunction Drives Diabetes-Induced Microvascular Dysfunction | |
| 在疫情期间，SARS-CoV-2基因组组成异质性呈现出加速下降的系统发育趋势。 | Oliver, J. L. | N/A | An accelerating, decreasing phylogenetic trend in SARS-CoV-2 genome compositional heterogeneity during the pandemic | |
| 杂交和基因流对基因共表达网络的影响 | Runghen, R. | N/A | Effects of hybridization and gene flow on gene co-expression networks | |
| 广泛存在的基因-环境相互作用塑造了住院COVID-19患者对SARS-CoV-2感染的免疫反应 | Randolph, H. E. | N/A | Widespread gene-environment interactions shape the immune response to SARS-CoV-2 infection in hospitalized COVID-19 patients | |
| 癌基因SLC35F2是一种对微量营养素喹啉和喹喔啉具有高特异性的转运体。 | Burtnyak, L. | N/A | The oncogene SLC35F2 is a high-specificity transporter for the micronutrients queuine and queuosine | |
| 鉴定针对淋病奈瑟菌丝氨酸乙酰转移酶的新型抑制剂 | Oldham, K. | N/A | Identification of novel inhibitors targeting serine acetyltransferase from Neisseria gonorrhoeae | |
| SMYD2-PARP1复合物的结构揭示了肽结合的生产性和变构性模式 | Zhang, Y. | N/A | Structure of the SMYD2-PARP1 Complex Reveals Both Productive and Allosteric Modes of Peptide Binding | |
| 基于瓶子的深度单细胞蛋白质组学一步预处理及其在卵母细胞老化中的应用 | Yang, Y. | N/A | Simple One-step Vial-based Pretreatment for Deep Single-cell Proteomics and Its Application to Oocyte Aging | |
| 利用FBXW7体细胞突变型R465C进行靶向蛋白质降解 | Basu, A. A. | N/A | Harnessing the FBXW7 somatic mutant R465C for targeted protein degradation | |
| 进化对位置序列、集体性质和原弹性蛋白序列风格施加了限制，这些限制是由形成和功能的基本要求所决定的，这些要求与细胞外弹性基质的形成和功能密切相关。 | Keeley, F. W. | N/A | Evolutionary Constraints on Positional Sequence, Collective Properties and Sequence Style of Tropoelastin Dictated by Fundamental Requirements for Formation and Function of the Extracellular Elastic Matrix | |
| tilvestamab与AXL复合物的结构分析 | Christakou, E. | N/A | Structural analysis of tilvestamab in complex with AXL | |
| 结核分枝杆菌感染的肺泡上皮细胞中的同位素示踪表明，其代谢特异性与其毒力和耐药状态相关。 | Akram, S. | N/A | Isotopic tracing in Mycobacterium tuberculosis-infected alveolar epithelial cells indicates metabolic specificity to their virulence and drug-resistance status | |
| 通过计算机预测域插入位点实现蛋白质别构开关的合理工程设计 | Wolf, B. | N/A | Rational engineering of allosteric protein switches by in silico prediction of domain insertion sites | |
| BEVA2.0：利用黄金门兼容向量进行模块化组装，扩展遗传工程应用 | Geddes, B. A. | N/A | BEVA2.0: Modular Assembly of Golden Gate-Compatible Vectors with Expanded Utility for Genetic Engineering | |
| HIV-1蛋白编码序列存在于相关细菌中。 | Pelaez-Prestel, H. F. | N/A | HIV-1 protein coding sequences are present in relevant bacteria | |
| 一种主要的昆虫寄生虫通过干扰白纹伊蚊传播基孔肯雅病毒。 | Martin, E. | N/A | A major entomoparasite interferes with Chikungunya transmission by Aedes albopictus | |
| 隐形眼镜佩戴改变了角膜上皮和细菌对铜绿假单胞菌的转录反应 | Kumar, N. G. | N/A | Contact Lens Wear Alters Transcriptional Responses to Pseudomonas aeruginosa in Both the Corneal Epithelium and the Bacteria | |
| 在奶牛场中，与临床相关的稳定蝇和粪便来源的细菌分离物中，抗菌药物抗性表型和基因的流行情况 | Sommer, A. J. | N/A | Prevalence of antimicrobial resistance phenotypes and genes in stable fly- and manure-derived bacterial isolates from clinically relevant taxa in dairy settings | |
| 血小板生物能量学与C57BL/6J小鼠骨骼肌代谢相关 | Wilkinson, M. S. | N/A | Platelet bioenergetics correlate with skeletal muscle metabolism in C57BL/6J mice | |
| RNA结合蛋白PRRC2B在饥饿期间保护5' TOP mRNA，以在营养恢复期间维持核糖体生物合成。 | Goldberg, N. | N/A | The RNA-binding protein PRRC2B preserves 5' TOP mRNA during starvation to maintain ribosome biogenesis during nutrient recovery | |
| 细胞原型图谱 | Crowley, G. | N/A | An Atlas of Cellular Archetypes | |
| 扩展HP1a结合的共识序列和异染色质组装的分子语法 | Colmenares, S. U. | N/A | Expanding the HP1a-binding consensus and molecular grammar for heterochromatin assembly | |
| D1是一种新型增强子阻断蛋白，其功能通过多个富含AT的简单序列重复实现。 | Kundurthi, P. | N/A | D1 is a novel enhancer blocker protein that functions via multiple AT-rich simple sequence repeats | |
| 谱系特异性氨基酸定义了Rad51和Dmc1重组酶单体-单体界面的功能属性 | Petassi, M. | N/A | Lineage-specific amino acids define functional attributes of the protomer-protomer interfaces for the Rad51 and Dmc1 recombinases | |
| CRISPR/AAV介导的精确基因组编辑在心脏应用 | Zheng, Y. | N/A | Cardiac Applications of CRISPR/AAV-Mediated Precise Genome Editing | |
| 皮肤元转录组学揭示了微生物活动和基因表达在整个人体中的变异景观 | Chia, M. | N/A | Skin metatranscriptomics reveals landscape of variation in microbial activity and gene expression across the human body | |
| PITHD1：细胞休眠期间26S蛋白酶体的内源性抑制剂 | Amann, S. J. | N/A | PITHD1: An Endogenous Inhibitor of the 26S Proteasome During Cellular Dormancy | |
| 多组学分析苜蓿和小麦诱发西藏绵羊瘤胃胀气的机制 | Zhao, W. | N/A | Multi-omics analysis of the mechanism of alfalfa and wheat-induced rumen flatulence in Xizang sheep | |
| 色素上皮衍生因子缺失使C57BL/6J小鼠对光诱导的视网膜损伤敏感 | Shelton, D. A. | N/A | Loss of Pigment Epithelium Derived Factor Sensitizes C57BL/6J Mice to Light-Induced Retinal Damage | |
| 一种预测单细胞蛋白质组学特性的算法 | Arroyo, J. I. | N/A | An algorithm for predicting per-cell proteomic properties | |
| 掌握曼努之技 - 人类如何制造巨大水花 | Rohilla, P. | N/A | Mastering the Manu - How humans create large splashes | |
| 口服烟酰胺核糖补充剂在DBA/2J小鼠模型中保护视网膜神经节细胞 | Zhang, N. | N/A | Oral supplementation with Nicotinamide Riboside treatment protects RGCs in DBA/2J mouse model | |
| 由植物乳杆菌SJ33产生的新型低分子量化合物对肺炎克雷伯菌的抗生物膜活性 | Ray Mohapatra, A. | N/A | Anti-biofilm activity of new low molecular weight compounds produced by Lactiplantibacillus plantarum SJ33 against Klebsiella pneumoniae | |
| 人类干细胞衍生的GABA能中间神经元发育揭示了早期亚型多样性的出现，随后是逐渐的电化学成熟过程。 | Bershteyn, M. | N/A | Human stem cell-derived GABAergic interneuron development reveals early emergence of subtype diversity followed by gradual electrochemical maturation | |
| 揭示人类大脑活动中的节奏分类 | Barbero, F. M. | N/A | Revealing rhythm categorization in human brain activity | |
| 自恋型和反社会型人格特质均编码于三重网络中：连接组学证据 | Jornkokgoud, K. | N/A | Narcissistic and Antisocial Personality Traits are both encoded in the Triple Network: Connectomics evidence | |
| 单细胞全长异构体测序揭示了在脑皮质发育过程中自闭症谱系障碍的转录失调 | Xu, X. | N/A | Single-Cell full-length Isoform Sequencing Unveils Transcriptional Dysregulation in Autism Spectrum Disorder During Cerebral Cortex Development | |
| 在羊膜动物中，半球间形态发生的保守性先于胼胝体（corpus callosum）的进化。 | Noji, R. | N/A | Conserved interhemispheric morphogenesis in amniotes preceded the evolution of the corpus callosum | |
| 组蛋白去甲基化酶KDM5在大脑中具有绝缘活性 | Yheskel, M. | N/A | The histone demethylase KDM5 has insulator activity in the brain | |
| 鸟类端脑和小脑的体积可以通过数字脑内模准确估算。 | Keirnan, A. R. | N/A | Avian telencephalon and cerebellum volumes can be accurately estimated from digital brain endocasts | |
| 背内侧纹状体的胆碱能中间神经元介导雄性小鼠社交层级动态中的胜者-败者效应。 | Hsu, M.-T. | N/A | Cholinergic interneurons of the dorsomedial striatum mediate winner-loser effects on social hierarchy dynamics in male mice. | |
| 在脑发育过程中，小胶质细胞中的组织蛋白酶B促进神经元的吞噬作用。 | Silva, N. J. | N/A | Microglial cathepsin B promotes neuronal efferocytosis during brain development | |
| 早期生活压力会损害活体前额叶-杏仁核网络内功能性相互作用和神经活动的发育 | Donati, A. | N/A | Early-life stress impairs development of functional interactions and neuronal activity within prefrontal-amygdala networks in vivo | |
| # BioRxiv 2024-12-03 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 不太本地化：玉米和类蜀黍趋同适应的群体遗传学。 | Tittes, S. | N/A | Not so local: the population genetics of convergent adaptation in maize and teosinte. | |
| 果蝇个体气味偏好的神经相关性 | Churgin, M. | N/A | A neural correlate of individual odor preference in Drosophila | |
| 在小鼠发育中的大脑皮层中，急性产前酒精暴露后DNA甲基化和转录组的即时扰动 | DUCHATEAU, A. | N/A | Immediate perturbation of DNA methylation and transcriptome upon acute prenatal alcohol exposure in the mouse developing brain cortex | |
| 雌性北棕林鸫（Troglodytes aedon）在对抗三种模拟捕食者时的风险评估 | Eggleston, R. C. | N/A | Risk assessment during nest defense against three simulated predators by female northern house wrens (Troglodytes aedon) | |
| xTrimoPGLM：统一100亿规模预训练变压器，用于解读蛋白质语言 | Chen, B. | N/A | xTrimoPGLM: Unified 100B-Scale Pre-trained Transformer for Deciphering the Language of Protein | |
| 通过果蝇模型识别心血管疾病与失眠之间的新关联，该模型基于一个多效性全基因组关联研究位点的基因 | Abou Daya, F. | N/A | Identifying novel links between cardiovascular disease and insomnia by Drosophila modeling of genes from a pleiotropic GWAS locus | |
| 抑制NINJ1依赖的质膜破裂可防止炎症小体诱导的血液凝固和炎症 | Wu, C. | N/A | Inhibiting NINJ1-dependent plasma membrane rupture protects against inflammasomeinduced blood coagulation and inflammation | |
| 常染色体显性多囊肾病（ADPKD）是由多囊蛋白-1（Polycystin-1）中的错义变异引起的，这些变异破坏了细胞表面定位或多囊蛋白通道功能。 | Ha, K. | N/A | ADPKD-Causing Missense Variants in Polycystin-1 Disrupt Cell Surface Localization or Polycystin Channel Function | |
| 视觉和触觉持续时间再现中的准确性反馈和延迟适应效应 | Chen, L. | N/A | Accuracy Feedback and Delay Adaptation Effects in Visual and Tactile Duration Reproduction | |
| 通过体内注射和电穿孔裸露mRNA恢复患有少弱畸精子症小鼠的精子生育力 | Vilpreux, C. | N/A | Sperm fertility restoration in mice suffering from oligo-astheno-teratozoospermia by in vivo injection and electroporation of naked mRNA | |
| DNA甲基组调控丁香假单胞菌的毒力和代谢 | Huang, J. | N/A | DNA Methylome Regulates Virulence and Metabolism in Pseudomonas syringae | |
| 真菌蛋白Jps1通过直接的磷脂酰肌醇相互作用促进非常规蛋白质分泌。 | Dali, S. | N/A | The fungal protein Jps1 facilitates unconventional protein secretion through a direct phosphoinositide interaction | |
| 细胞周期和年龄相关的小鼠染色体刚性调节 | Liu, N. | N/A | Cell-cycle and Age-Related Modulations in Mouse Chromosome Stiffness | |
| 果蝇科温度偏好行为的演变 | Kafle, T. | N/A | Evolution of temperature preference behaviour among drosophilids | |
| 基于宏转录组学的感染期间患者特异性尿液微生物组的代谢建模 | Josephs-Spaulding, J. | N/A | Metatranscriptomics-based metabolic modeling of patient-specific urinary microbiome during infection | |
| 自然行为中视觉运动协调的低维表示 | Keshava, A. | N/A | Low-Dimensional Representations of Visuomotor Coordination for Natural Behavior | |
| 一种可调且多功能的近红外荧光化学遗传报告器 | El Hajji, L. | N/A | A tunable and versatile chemogenetic near infrared fluorescent reporter | |
| 行走的果蝇中运动统计的抑制性控制 | Gattuso, H. | N/A | Inhibitory control of locomotor statistics in walking Drosophila | |
| 一种多状态捕获-重捕模型，用于估计北大西洋露脊鲸的繁殖情况。 | Linden, D. W. | N/A | A multistate capture-recapture model to estimate reproduction of North Atlantic right whales | |
| 基于能量的适应性免疫 repertoire 行为系统建模：细胞增殖与体细胞超突变过程研究 | Chen, Y. | N/A | Energy-Based Systematic Modeling of Adaptive Immune Repertoire Behavior: Study on Cell Proliferation & Somatic Hypermutation process | |
| Q175亨廷顿病模型小鼠中mTOR抑制促进神经元自噬及突变亨廷顿蛋白清除 | Stavrides, P. | N/A | mTOR inhibition in Q175 Huntington's disease model mice facilitates neuronal autophagy and mutant huntingtin clearance | |
| 斑马鱼肠道中的蛋白质吸收受到富含溶酶体的肠细胞与微生物群之间相互作用的调控。 | Childers, L. | N/A | Protein absorption in the zebrafish gut is regulated by interactions between lysosome rich enterocytes and the microbiome | |
| 分流细胞的瞬态和动态特性源自其行为。 | Chaix-Echel, N. | N/A | The transient and dynamic nature of splitter cells derive from behavior | |
| 结构变异对玉米表型变异有贡献 | Catlin, N. S. | N/A | Structural variants contribute to phenotypic variation in maize | |
| 在不增加训练或数据的情况下提高逆折叠模型在蛋白质稳定性预测中的表现 | Dutton, O. | N/A | Improving Inverse Folding models at Protein Stability Prediction without additional Training or Data | |
| 利用时间维度和光谱维度实现多样性热带森林中的综合单木树种制图 | Ball, J. G. C. | N/A | Towards comprehensive individual tree species mapping in diverse tropical forests by harnessing temporal and spectral dimensions | |
| 细胞拥挤会诱导TRPV4的抑制及其向质膜的重新定位，暗示了促进侵袭的细胞体积减少机械转导途径。 | Bu, X. | N/A | Cell crowding induces TRPV4 inhibition and its relocation to plasma membranes, implicating pro-invasive cell volume reduction mechanotransduction pathway | |
| 利用动力学信息提高基因组规模代谢模型的准确性 | Lazaro Ibanez, J. | N/A | Enhancing the accuracy of genome-scale metabolic models with kinetic information | |
| 错位视网膜轴突在白化小鼠的视觉丘脑中诱导出一种突触独立的子回路。 | McCracken, S. | N/A | Mistargeted retinal axons induce a synaptically independent subcircuit in the visual thalamus of albino mice. | |
| 两个相互作用细胞之间对齐机制的动力学分析 | Leech, V. | N/A | A dynamical analysis of the alignment mechanism between two interacting cells | |
| 基于结构的RyR通道操作机制：钙离子和镁离子的作用 | Zahradnikova, A. | N/A | Structure-based mechanism of RyR channel operation by calcium and magnesium ions | |
| 基因组数据显示，非洲各地的血吸虫（Schistosoma haematobium）种群存在南北分化及基因渐渗历史。 | Platt, R. N. | N/A | Genomic data reveal a north-south split and introgression history of blood fluke (Schistosoma haematobium) populations from across Africa | |
| 解决功能神经影像学中的不一致性：一种可复制的、数据驱动的多尺度功能图谱，用于标准脑网络 | Jensen, K. M. | N/A | Addressing inconsistency in functional neuroimaging: A replicable data-driven multi-scale functional atlas for canonical brain networks | |
| 一种综合方法，用于提取经历液-液相分离的球状蛋白质的旋转动力学 | Gendreizig, D. | N/A | A combined approach to extract rotational dynamics of globular proteins undergoing liquid-liquid phase separation | |
| 纤维化中异位肺泡基底细胞相对于气道基底细胞的特征 | Blumer, S. | N/A | Characteristics of ectopic alveolar basal cells relative to airway basal cells in fibrosis | |
| inPhase - 一种简单、准确且快速的方法来确定蛋白质凝聚相图 | Fritsch, A. W. | N/A | inPhase - A simple, accurate and fast approach to determine phase diagrams of protein condensates | |
| 有丝分裂后依赖PP2A-Ankle2的核重构机制 | Li, J. | N/A | Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis | |
| 一种肿瘤胚胎学方法揭示了SoxC驱动的结肠发育和癌症调控机制 | Dalessi, T. | N/A | An oncoembryology approach uncovers SoxC-driven regulation of colon development and cancer | |
| 淀粉样前体蛋白（Amyloid Beta Precursor Protein）有助于短命的绿松石鳉鱼（Nothobranchius furzeri）的脑老化和学习能力下降。 | de Bakker, D. E. M. | N/A | Amyloid Beta Precursor Protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri) | |
| 由祖先SARS-CoV-2印记的B细胞在免疫回忆中产生广谱的沙贝病毒中和能力 | Chen, X. | N/A | B cells imprinted by ancestral SARS-CoV-2 develop pan-sarbecovirus neutralization in immune recalls | |
| TreeFormer：一种基于Transformer的树重排操作，用于系统发育重建 | Ly-Trong, N. | N/A | TreeFormer: A transformer-based tree rearrangement operation for phylogenetic reconstruction | |
| 基于片段的小分子抑制剂开发，靶向结核分枝杆菌胆固醇代谢 | Kavanagh, M. E. | N/A | Fragment-based development of small molecule inhibitors targeting Mycobacterium tuberculosis cholesterol metabolism | |
| ERP和神经振荡能否用于在一个生态有效的运动模型中区分熟练和非熟练玩家的表现？ | Winstanley, M. | N/A | Can ERPs and neural oscillations be used to differentiate skilled and unskilled player performance in an ecologically valid sporting model? | |
| 药物的环境影响：对近期关于水生浓度及可预测效应数据的证据映射回顾 | Renda, F. | N/A | The environmental impact of pharmaceuticals: an evidence-mapping review of recent data on aquatic concentrations and predictable effects | |
| 甲型流感病毒的转录产生加帽的cRNA，这些cRNA能够激活RIG-I。 | Elshina, E. | N/A | Influenza A virus transcription generates capped cRNAs that activate RIG-I | |
| 一种简单的新替代线性-二次模型（以及LQ模型的来源） | Bilinsky, L. | N/A | A simple new alternative to the linear-quadratic model (and where the LQ model comes from) | |
| 对Diversity Outbred小鼠研究中寿命的分析确定了多个与长寿相关的位点 | Mullis, M. N. | N/A | Analysis of lifespan across Diversity Outbred mouse studies identifies multiple longevity-associated loci | |
| 原位整合多孔聚乙烯纳米膜与伤口渗出液以实现无痕愈合 | Yuan, S. | N/A | In Situ Integration of Porous Polyethylene Nanomembrane with Wound Exudates for Scarless Healing | |
| 高分辨率分析揭示了转基因的转录和翻译调控的耦合关系 | Peterman, E. L. | N/A | High-resolution profiling reveals coupled transcriptional and translational regulation of transgenes | |
| 广泛存在的肠杆菌过氧化物酶封装体的结构和生化特性 | Ubilla-Rodriguez, N. C. | N/A | Structural and biochemical characterization of a widespread enterobacterial peroxidase encapsulin | |
| 对动力蛋白-动力蛋白激活蛋白-NuMA复合物的激活和调控的结构与功能解析 | Aslan, M. | N/A | Structural and functional insights into activation and regulation of the dynein-dynactin-NuMA complex | |
| 过度活跃的神经网络促进阿尔茨海默病小鼠模型中的tau蛋白扩散 | Barbour, A. J. | N/A | Hyperactive neuronal networks facilitate tau spread in an Alzheimer's disease mouse model | |
| 果蝇对细菌肽聚糖的感知反应整合了正向和负向信号 | Montanari, M. | N/A | Drosophila's sensory responses to bacterial peptidoglycan integrates positive and negative signals | |
| 哺乳动物增强子和全基因组关联研究（GWASs）主要在基因附近发挥作用，很少跨越活跃基因。 | Choudhary, C. | N/A | Mammalian enhancers and GWASs act proximally and seldom skip active genes | |
| 玉米裸粒的古老起源 | Fairbanks, R. A. | N/A | An ancient origin of the naked grains of maize | |
| 玉米及相关物种中生殖屏障的分子进化 | Cryan, E. | N/A | Molecular evolution of a reproductive barrier in maize and related species | |
| 根癌农杆菌A4衍生菌株在烟草和其它茄科植物中实现超高效瞬时基因表达 | Lopez-Agudelo, J. C. | N/A | Rhizobium rhizogenes A4-derived strains mediate hyper-efficient transient gene expression in Nicotiana benthamiana and other solanaceous plants | |
| 机械应力引导气孔分裂，形成组织尺度的排列。 | Serra, L. | N/A | Mechanical stress orients stomata division to form tissue scale alignments. | |
| 番茄疫霉病潜在生物防治剂的时空化学研究 | Robinson, J. Y. | N/A | Spatiochemical Investigation of Potential Biocontrol Agents Against Phytophthora capsici Infection in Tomato | |
| 由亚麻锈病菌Melampsora lini介导的效应蛋白向植物细胞的转运 | Zhang, X. | N/A | Translocation of effector proteins into plant cells by the flax rust pathogen Melampsora lini | |
| 通过宿主到群体的计算机病毒进化，利用深度学习实现生成式流行突变预测 | Liu, X. | N/A | Deep-learning-enabled generative prevalent mutation prediction through host-to-herd in silico virus evolution | |
| MAAPE：一种模块化蛋白质嵌入进化分析方法 | Wang, X. | N/A | MAAPE: A Modular Approach to Evolutionary Analysis of Protein Embeddings | |
| 昆虫对植物挥发性物质的气相色谱-耦合电位图检测（GC-EAD）的定量分析 | Byers, K. J. R. P. | N/A | Quantitative analysis of gas chromatography-coupled electroantennographic detection (GC-EAD) of plant volatiles by insects | |
| 植物机械应答中细胞骨架和质体骨架蛋白的功能、生物素化蛋白质组学和生物信息学分析 | WU, K. | N/A | Functional, Biotinylproteomic and Bioinformatic Analysis of Both Cytoskeletal and Plastoskeletal Proteins in Plant Mechanoresponse | |
| 保守效应因子支撑了从苔藓中分离出的假单胞菌在不同植物中的致病性 | Robinson, K. | N/A | Conserved effectors underpin the virulence of liverwort-isolated Pseudomonas in divergent plants | |
| 性别偏倚基因表达在性对抗选择和性限制选择下的表现 | Wiberg, R. A. W. | N/A | Sex-biased gene expression under sexually antagonistic and sex-limited selection | |
| 可解释人工智能引导的植物中选择性siRNA积累的新型蛋白质-RNA相互作用框架的鉴定 | Enoki, N. | N/A | Explainable AI-guided identification of a novel protein-RNA interactive frame for selective siRNA accumulation in plants | |
| 生成式人工智能的分化：大学生背景如何影响其生成式AI素养 | Jiang, J. | N/A | Generative AI divide: How College Students' Backgrounds Affect Their Gen AI Literacy | |
| TET敲除细胞在多能态之间转换，并表现出过早的生殖系进入。 | Chambers, I. | N/A | TET knockout cells transit between pluripotent states and exhibit precocious germline entry | |
| 性二态性与间性关联：模型是否支持直觉？ | Puixeu, G. | N/A | The relationship between sexual dimorphism and intersex correlation: do models support intuition? | |
| 解开适应性与非适应性过程在Coenonympha蝴蝶生殖隔离进化中的贡献。 | Capblancq, T. | N/A | Untangling the contribution of adaptive versus non-adaptive processes in the evolution of reproductive isolation between Coenonympha butterflies. | |
| 数字DNA系统揭示了单向遗传相对于“拉马克式”遗传的优越性 | Shiju, A. | N/A | A digital DNA system reveals the superiority of unidirectional inheritance over 'Lamarckian' inheritance | |
| 通过mitology R包解析转录组数据中的线粒体活性 | Pirrotta, S. | N/A | Dissect mitochondrial activity by transcriptome data with mitology R package | |
| 人类糖皮质激素受体变异体rs6190促进血液胆固醇水平和动脉粥样硬化的发生。 | Durumutla, H. B. | N/A | The human glucocorticoid receptor variant rs6190 promotes blood cholesterol and atherosclerosis | |
| 雌激素信号在Reprimo谱系细胞中的性别特异性体温调节作用 | Park, J. W. | N/A | Sex-specific thermoregulatory effects of estrogen signaling in Reprimo lineage cells | |
| 光量影响拟南芥幼叶对寒冷的早期反应和冷适应 | Luklova, M. | N/A | Light quantity impacts early response to cold and cold acclimation in young leaves of Arabidopsis | |
| 拟南芥花粉管向性调控因子PCP-B与RALF23/33竞争结合的结构基础 | Bhalla, H. | N/A | Structural Insights into Competitive Binding Dynamics between RALF23/33 and PCP-B in Brassicaceae Pollination | |
| 单核测序揭示了Moricandia arvensis中束鞘细胞在C3-C4中间型十字花科植物光呼吸穿梭中的功能 | Triesch, S. | N/A | Single-nuclei sequencing of Moricandia arvensis reveals bundle sheath cell function in the photorespiratory shuttle of C3-C4 intermediate Brassicaceae | |
| 从头设计的pMHC结合剂促进T细胞介导的癌细胞杀伤 | Johansen, K. H. | N/A | De novo designed pMHC binders facilitate T cell induced killing of cancer cells | |
| 一个评分统治所有：基于GWAS汇总统计的正则化集成多基因风险预测 | Zhao, Z. | N/A | One score to rule them all: regularized ensemble polygenic risk prediction with GWAS summary statistics | |
| 犬持续性苗勒管综合征：对AMH和AMHR2基因组织的新见解 | Krzeminska, P. | N/A | Persistent Mullerian duct syndrome in dogs: a new insight into organization of AMH and AMHR2 genes | |
| 移植后间充质细胞的单细胞多组学分析揭示了肺纤维化的分子特征及潜在调控因子 | Lu, L. | N/A | Single-cell multi-omic analysis of post-transplant mesenchymal cells reveals molecular signatures and putative regulators of lung fibrosis | |
| 移植后间充质细胞的单细胞多组学分析揭示了肺纤维化的分子特征及潜在调控因子 | Lu, L. | N/A | Single-cell multi-omic analysis of post-transplant mesenchymal cells reveals molecular signatures and putative regulators of lung fibrosis | |
| 中性粒细胞在实验性牙周炎中驱动性别二态性 | Martin, K. | N/A | Neutrophils drive sexual dimorphism in experimental periodontitis | |
| 环境毒素衍生的α-突触核蛋白对肠神经-上皮相互作用的性别特异性影响 | Templeton, H. N. | N/A | Sex specific effects of environmental toxin-derived alpha synuclein on enteric neuronal-epithelial interactions | |
| 早期接触西方饮食会加剧雌性小鼠的视觉结果。 | Meseguer, D. | N/A | Early exposure to Western diet exacerbates visual outcomes in female mice. | |
| 探索类胡萝卜素对致病性尖孢镰刀菌（Fusarium oxysporum f.sp. lini）和内生菌Fo47菌株的影响 | Kochneva, Y. | N/A | Exploring the Impact of Apocarotenoids on Pathogenic Fusarium oxysporum f.sp. lini and Endophytic Fo47 strains | |
| 调节APC/C调控因子SlSAMBA的活性可提高番茄果实的糖分和抗氧化物质含量 | de Oliveira, P. N. | N/A | Modulating activity of the APC/C regulator SlSAMBA improves the sugar and antioxidant content of tomato fruits | |
| 去除表皮蜡质对角质层蜡质沉积速率没有影响，成熟桂樱叶的角质层蜡质沉积速率是恒定的。 | Janova, J. | N/A | Removal of epicuticular wax has no effect on the rate of cuticular wax deposition, which is constant in mature cherry laurel leaves | |
| 多功能的IL-21+ IFNg+ T滤泡辅助细胞有助于检查点抑制剂糖尿病的发生，并可通过JAK抑制剂疗法进行靶向治疗。 | Huang, N. | N/A | Polyfunctional IL-21+ IFNg+ T follicular helper cells contribute to checkpoint inhibitor diabetes mellitus and can be targeted by JAK inhibitor therapy | |
| 改进人工智能与现有生态推断工作流程的整合 | Cowans, A. | N/A | Improving the integration of AI into existing ecological inference workflows | |
| 伊朗希尔卡尼亚森林中丛林猫的车辆碰撞风险建模：车辆碰撞预防指南 | Ashoori, A. | N/A | Modeling vehicle collision risk for the jungle cat in the Hyrcanian forests of Iran: A guide for vehicle collision prevention | |
| 量化单细胞数据中的病理进展 | Khan, S. R. | N/A | Quantifying Pathological Progression from Single-Cell Data | |
| C2AM-Unet：用于视网膜血管分割的坐标与通道注意力混合灵活架构 | Zhang, J. | N/A | C2AM-Unet: Coordinate and Channel Attention Mixing Flexible Architecture for Retinal Vessel Segmentation | |
| 亚马逊药用植物中潜在的抗病毒和免疫调节化合物 | Napoleao, S. M. d. S. | N/A | Potential antiviral and immunomodulatory Amazonian medicinal plant compounds | |
| 结构趋同和水介导的底物模拟使人类抗体能够广泛抑制神经氨酸酶 | Lederhofer, J. | N/A | Structural Convergence and Water-Mediated Substrate Mimicry Enable Broad Neuraminidase Inhibition by Human Antibodies | |
| 健康人体免疫系统和微生物群的协调变化与持续性干扰素状态有关。 | Babdor, J. | N/A | Coordinated variation in the immune systems and microbiomes of healthy humans is linked to tonic interferon states | |
| 单细胞基因表达的动力学模式可区分小鼠对减毒活疫苗和灭活黄热病疫苗的细胞反应 | Chatterjee, B. | N/A | Kinetic patterns of single cell gene expression discriminate between the murine cellular responses to live attenuated and inactivated Yellow Fever vaccines | |
| 从公民科学和深度学习对珊瑚礁进行大规模勘察 | Lawson, C. L. | N/A | Broadscale reconnaissance of coral reefs from citizen science and deep learning | |
| 波卡：一只负载比高达6847%的死灵机器人甲虫 | Tsvetkov, Y. | N/A | Poka: a necro-robot beetle with a measured payload ratio of 6847% | |
| 核苷酸GPT：基于序列的深度学习预测核亚区室相关基因组结构 | Mclaughlin, S. M. | N/A | Nucleotide GPT: Sequence-Based Deep Learning Prediction of Nuclear Subcompartment-Associated Genome Architecture | |
| 重塑乳腺癌肝转移局部治疗格局：一种新型瘤内p21靶向经皮疗法可提高BALB/c小鼠接种4T1三阴性乳腺癌细胞后的生存率。 | Margulies, B. S. | N/A | Reshaping the Landscape of Locoregional Treatments for Breast Cancer Liver Metastases: A novel, intratumoral, p21-targeted percutaneous therapy increases survival in BALB/c mice inoculated with 4T1 triple negative breast cancer cells in the liver. | |
| TLR7/8激动剂INI-4001增强了Powassan病毒样颗粒疫苗的免疫原性。 | Crawford, M. W. | N/A | The TLR7/8 agonist INI-4001 enhances the immunogenicity of a Powassan virus-like-particle vaccine | |
| 浮游牡蛎幼虫在复杂的感官环境中优化定居决策 | Schmidlin, S. | N/A | Planktonic oyster larvae optimize settlement decisions in complex sensory landscapes | |
| 新型Hybprinter-SAM的开发：用于具有图案化和局部生化信号的功能梯度组织工程构建体 | Li, J. | N/A | Development of a Novel Hybprinter-SAM for Functionally Graded Tissue Engineering Constructs with Patterned and Localized Biochemical Signals | |
| 体内在线无标记监测光疗过程中异质性氧利用率，实时超声引导光声成像 | Langley, A. | N/A | In vivo Online label-free monitoring of heterogenous oxygen utilization during phototherapy with real-time ultrasound guided photoacoustic imaging | |
| ReSCU-Nets：用于多维显微镜数据分割的递归U-Nets | Hawkins, R. | N/A | ReSCU-Nets: recurrent U-Nets for segmentation of multidimensional microscopy data | |
| AlphaPulldown2 - 一种用于高通量结构建模的通用流程 | Molodenskiy, D. | N/A | AlphaPulldown2 - A General Pipeline for High-Throughput Structural Modeling | |
| 在单细胞和空间组学数据中检测亚群的度量标准 | Luo, S. | N/A | On metrics for subpopulation detection in single-cell and spatial omics data | |
| 针对G蛋白偶联受体的特定状态多肽设计 | Xue, Y. | N/A | State-specific Peptide Design Targeting G Protein-coupled Receptors | |
| 深度学习方法在RNA三级结构预测中的比较综述 | Martinovic, I. | N/A | A Comparative Review of Deep Learning Methods for RNA Tertiary Structure Prediction | |
| ACE：一种用于单细胞镶嵌整合的多功能对比学习框架 | Yan, X. | N/A | ACE: a versatile contrastive learning framework for single-cell mosaic integration | |
| VBayesMM：用于优先处理高维微生物组多组学数据重要关系的变化贝叶斯神经网络 | Dang, T. | N/A | VBayesMM: Variational Bayesian neural network to prioritize important relationships of high-dimensional microbiome multiomics data | |
| 细胞类型特异性表观基因组亚型分类提高了癌症预后分层的准确性。 | Luo, Q. | N/A | Cell-type specific subtyping of epigenomes improves prognostic stratification of cancer | |
| 通过内部驱动的定向力实现细胞片层形状转变 | Huang, J. | N/A | Cell-sheet shape transformation by internally-driven, oriented forces | |
| 利用大型语言模型解决空间转录组学数据解读的复杂性 | Khan, T. | N/A | Tackling the Complexity of Spatial Transcriptomics Data Interpretation with Large Language Models | |
| 通过机械疗法和超声波穿透技术优化实体瘤的治疗效果 | Koutsi, M. | N/A | Optimizing therapeutic outcomes with Mechanotherapy and Ultrasound Sonopermeation in solid tumors | |
| 人胰腺肿瘤和小肠微生物群的分离与鉴定 | Awad, D. | N/A | Isolation and characterization of microbiota from human pancreatic tumors and small intestine | |
| 推进白细胞检测：形态学分析的多领域数据集及应对稀疏标注挑战 | Rehman, A. | N/A | Advancing White Blood Cell Detection: A Multi-Domain Dataset for Morphological Analysis and Addressing Sparse Annotation Challenges | |
| SS-31可预防博来霉素诱导的肺损伤和纤维化。 | Gu, Q. | N/A | SS-31 protects against bleomycin-induced lung injury and fibrosis | |
| 面向营养不良的综合解决方案：新型即用型治疗食品测试的综合临床前协议 | Utume, L. | N/A | Toward Holistic Solutions to Undernutrition: A Comprehensive Preclinical Protocol for Novel Ready-to-Use Therapeutic Foods Testing | |
| 拟南芥生殖阶段莲座叶的年龄依赖性缺铁差异响应 | Ngigi, M. | N/A | Age-dependent differential iron deficiency responses of rosette leaves during reproductive stages in Arabidopsis thaliana | |
| 瞬时转录因子耗竭解释了LexA目标启动子对轻度DNA损伤的多样性单细胞响应 | Galbusera, L. | N/A | Transient transcription factor depletions explain diverse single-cell responses of LexA target promoters to mild DNA damage | |
| ST6GAL1介导的肿瘤相关巨噬细胞唾液酸连接转换促进抗炎细胞中携带α2,6-唾液酸化的促癌纳米管形成 | Dipta, P. | N/A | ST6GAL1-mediated sialyl linkage switching in tumor-associated macrophages drives cancer-promoting nanotubes carrying α2,6-sialylation in anti-inflammatory cells | |
| 静脉注射猪血浆胞外颗粒对大鼠的可行性——一项急性研究 | Chernavsky, N. | N/A | Feasibility of intravenous injections of pig plasma extracellular particles into rats -- an acute study | |
| 结合13C、15N和2H测量海洋浅水海绵的摄食和代谢活动——一项试点研究 | Stratmann, T. | N/A | Combining 13C, 15N, and 2H to measure feeding and metabolic activity in marine, shallow-water sponges - A pilot study | |
| 利用多时相和多传感器遥感数据预测林地鸟类物种栖息地 | Kuzmich, R. J. | N/A | Predicting woodland bird species habitat with multi-temporal and multisensor remote sensing data | |
| 大规模信息先验以更好地预测稀有树相关微生境的局部发生率 | Cottais, P. | N/A | Large-scale informative priors to better predict the local occurrence rate of a rare tree-related microhabitat | |
| 深层土壤微生物群落的功能组成随橡树死亡而变化 | Goodman, A. C. | N/A | Functional composition of deep soil microbial communities changes with oak mortality | |
| 在自然啮齿动物种群中，超级传播者具有较低的肠道微生物α多样性以及独特的肠道微生物组成。 | Wanelik, K. M. | N/A | Superspreaders have lower gut microbial alpha-diversity and distinct gut microbial composition in a natural rodent population | |
| 由凝聚蛋白和CTCF调控的基因表达统一模型 | Choudhary, C. | N/A | A unified model of gene expression control by cohesin and CTCF | |
| 使用空间分子成像技术对固定在福尔马林固定石蜡包埋（FFPE）组织上的整个蛋白质编码人类转录组（18933-plex）进行亚细胞成像 | Khafizov, R. | N/A | Sub-cellular Imaging of the Entire Protein-Coding Human Transcriptome (18933-plex) on FFPE Tissue Using Spatial Molecular Imaging | |
| 稳态和刺激下人类骨骼肌细胞代谢性状相关基因调控的功能性解析 | Nishino, K. | N/A | Functional dissection of metabolic trait-associated gene regulation in steady state and stimulated human skeletal muscle cells | |
| 在外部机械刺激下，悬浮成纤维细胞片中的力学感应复合物发生动态重塑 | Suzuki, M. | N/A | Dynamic remodeling of mechano-sensing complexes in suspended fibroblast cell-sheets under external mechanical stimulus | |
| gplasCC：从任何细菌物种的短读测序数据中对质粒进行分类和重建 | Paganini, J. A. | N/A | gplasCC: classification and reconstruction of plasmids from short-read sequencing data for any bacterial species | |
| 一个强大的通用风险因素差异共表达分析框架 | Bass, A. J. | N/A | A powerful framework for differential co-expression analysis of general risk factors | |
| 使用转录组规模上下文扩展单细胞的密集表示 | Ho, N. | N/A | Scaling Dense Representations for Single Cell with Transcriptome-Scale Context | |
| RCVT：一种用于量化系统基因组学中分类群间组成偏倚的新型诊断方法 | Steenwyk, J. L. | N/A | RCVT: a novel diagnostic to quantify compositional biases among taxa for phylogenomics | |
| 使用Deconomix在Python中对组学数据进行反卷积——细胞组成、细胞类型特异性基因调控及背景贡献 | Altenbuchinger, M. C. | N/A | Deconvolution of omics data in Python with Deconomix -- cellular compositions, cell-type specific gene regulation, and background contributions | |
| Martini 3力场中优化的蛋白质-辅料相互作用 | Prass, T. M. | N/A | Optimized Protein-Excipient Interactions in theMartini 3 Force Field | |
| 银(I)离子与氨基酸侧链之间的精确相互作用：基于12-6 Lennard-Jones势的从底向上参数化方法 | Manciocchi, L. | N/A | Accurate interaction between silver(I) ion and amino acid side chains with the 12-6 Lennard-Jones potential: a bottom-up parameterization approach | |
| DNA错配修复蛋白MSH6是一种PD-L1表达的新型调节因子。 | Brooksbank, K. | N/A | The DNA Mismatch repair protein, MSH6 is a novel regulator of PD-L1 expression | |
| 肝细胞癌相关的AXIN1突变驱动Wnt/β-连环蛋白通路活性降低，这种低水平的通路活性使得癌细胞能够在不依赖微环境的情况下生长，并激活YAP/TAZ信号传导。 | Venhuizen, A. J. | N/A | Hepatocellular carcinoma-associated AXIN1 mutations drive low levels of Wnt/β-catenin pathway activity that allow for niche-independent growth and YAP/TAZ signaling | |
| HIFα异构体特异性活性驱动与VHL相关的肿瘤发生的细胞类型特异性 | Lima, J. D. C. C. | N/A | HIFalpha isoform specific activities drive cell-type specificity of VHL-associated oncogenesis | |
| IKZF2-ERBB4基因融合导致肛门鳞状细胞癌中ERBB4的过度表达，但对ERBB4的抑制并无益处。 | RICHON, S. | N/A | IKZF2-ERBB4 gene fusion leads to ERBB4 overexpression in Anal Squamous Cell Carcinoma but with no benefit for ERBB4 inhibition | |
| microRNA-544a作为关节软骨和骨关节炎中Wnt信号网络的新调节因子 | Heluany, C. S. | N/A | microRNA-544a as a new modulator of the Wnt-signalling network in the articular cartilage and osteoarthritis | |
| Mavacamten促进肌球蛋白头部从开启到关闭的转变，并在松弛的骨骼肌中缩短细丝长度。 | Kuehn, M. N. | N/A | Mavacamten facilitates myosin head ON-to-OFF transitions and shortens thin filament length in relaxed skeletal muscle | |
| 性依赖的潜在冷害改变了模型昆虫热耐受性的估计 | El-Saadi, M. I. | N/A | Sex-dependent latent chilling injury changes estimates of thermal tolerance in a model insect | |
| 股四头肌运动单元的放电特性及其随收缩水平的变化依赖于膝关节角度 | Valencic, T. | N/A | Motor unit discharge properties of the vastii muscles and their modulation with contraction level depend on the knee-joint angle | |
| 针对糖尿病心脏病的靶向糖吞噬ATG8疗法 | Mellor, K. M. | N/A | Targeted glycophagy ATG8 therapy for diabetic heart disease | |
| PlantRing：一种用于解码植物生长、水分关系并创新灌溉技术的高通量可穿戴传感器系统 | Sun, T. | N/A | PlantRing: A high-throughput wearable sensor system for decoding plant growth, water relations and innovating irrigation | |
| 一种新的PGRL1旁系同源基因优化了草类光保护的调控，并促进了C4光合作用中的细胞特化。 | Nix, S. J. | N/A | A novel PGRL1 paralog refined the control of photoprotection in grasses and facilitated cell specialisation in C4 photosynthesis | |
| 编辑OsPHO1;2的顺式作用元件提高了水稻的磷酸盐转运和产量 | Maurya, K. | N/A | Editing cis-elements of OsPHO1;2 improved phosphate transport and yield in rice | |
| 人源间充质基质细胞衍生的线粒体在术后消化道瘘大鼠模型中的治疗潜力：迈向能量纳米生物疗法 | Mariani, A. | N/A | Therapeutic potential of human mesenchymal stromal cell-derived mitochondria in a rat model of post-surgical digestive fistula: towards an energetic nano-biotherapy | |
| 爆炸性同步的临近程度决定了神经和经济危机中的网络崩溃和恢复轨迹 | Lee, U. | N/A | Proximity to Explosive Synchronization Determines Network Collapse and Recovery Trajectories in Neural and Economic Crises | |
| 通过超解景观构建细胞命运决定的全面图谱 | Zhang, X. | N/A | Constructing a holistic map of cell fate decision by hyper solution landscape | |
| 增加的NFAT和NFκB信号传导有助于囊性纤维化患者对烟曲霉感染产生的过度炎症表型。 | Bercusson, A. | N/A | Increased NFAT and NFκB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in cystic fibrosis | |
| 追踪癌症免疫治疗中抗原特异性T细胞反应 | Shagina, I. A. | N/A | Tracking antigen-specific T cell response to cancer immunotherapy | |
| 金黄色葡萄球菌通过NKG2A介导的天然杀伤细胞免疫调控 | Davies, K. | N/A | NKG2A-mediated immune modulation of natural killer cells by Staphylococcus aureus | |
| 分类学变化对亚马逊棕榈植物区系的影响 | Stropp, J. | N/A | Impacts of taxonomic change on the Amazonian palm flora | |
| 选择增强了植物多样性与车前草代谢特征之间的关系 | Medina-van Berkum, P. | N/A | Selection strengthens the relationship between plant diversity and the metabolic profile of Plantago lanceolata | |
| 保护鬣蜥多样性：通过陆地环境DNA创新实现非本土鬣蜥的快速低成本追踪 | Kuijk, J. | N/A | Safeguarding Iguana diversity: Enabling rapid and low-effort tracking of non-native iguanas through terrestrial eDNA innovations | |
| 利用动物追踪进行大规模中毒事件的早期检测 | Curk, T. | N/A | Using animal tracking for early detection of mass poisoning events | |
| 线虫类寄生虫粪类圆线虫是否为犬类动物的动物传染病？——基于群体遗传学的方法。 | :iu, Y. | N/A | Is the nematode Strongyloides stercoralis a zoonosis from dogs? - a population genetics approach. | |
| CGMFinder 从 3H scRNA-seq 数据中识别相关基因模块 | Ma, W. | N/A | CGMFinder Identifies Correlated Gene Modules from 3H scRNA-seq Data | |
| 超越运动皮层：对颅内语音神经假体目标位置的脑区评估 | Verwoert, M. | N/A | Moving beyond the motor cortex: a brain-wide evaluation of target locations for intracranial speech neuroprostheses | |
| P4ward：一种用于Protac三元复合物自动建模的平台 | Jofily, P. | N/A | P4ward: an automated modelling platformfor Protac ternary complexes | |
| 专家混合模型助力高效且有效的蛋白质理解和设计 | Sun, N. | N/A | Mixture of Experts Enable Efficient and Effective Protein Understanding and Design | |
| Semaglutide类似物增强GLP-1R激活：动态结构与静电学视角 | Li, W. | N/A | Semaglutide Analogues Enhancing GLP-1R Activation: A Dynamic Structural & Electrostatic Perspective | |
| 病毒模拟将免疫抑制的结直肠肿瘤微环境重定向为促炎性和CMS1样再生状态 | Corry, S. M. | N/A | Viral mimicry redirects immunosuppressed colorectal tumour landscapes towards a proinflammatory and CMS1-like regenerative state | |
| 错配修复缺陷对同基因小鼠模型中转移发生的影响 | Laplante, P. | N/A | Effect of MisMatch Repair Deficiency on metastasis occurrence modelized in a syngeneic mouse model | |
| PAG通过与肌动蛋白结合，协调T细胞免疫突触的功能。 | Moore, E. K. | N/A | PAG orchestrates T cell immune synapse function by binding to actin | |
| 基于血液组学的系统特异性死亡风险评估模型 | Fuentealba, M. | N/A | Blood Omics Models for System-Specific Mortality Risk Estimation | |
| 单细胞转录组学揭示了人类肠道中肥大细胞的异质性 | Hussein, H. | N/A | Single cell transcriptomics reveal mast cell heterogeneity in the human gut | |
| 全球生物医学和生物技术重要真菌属曲霉的物种多样性和分布模式 | Riedling, O. L. | N/A | Global patterns of species diversity and distribution in the biomedically and biotechnologically important fungal genus Aspergillus | |
| 利用性别依赖的基因表达模式进行精确的混合单细胞RNA测序样本解卷积 | Twa, G. M. | N/A | Accurate sample deconvolution of pooled snRNA-seq using sex-dependent gene expression patterns | |
| 利用金刚石中的氮-空位中心探测纳米尺度电化学现象 | Fulton, S. | N/A | Probing Nanoscale Electrochemical Phenomena with Nitrogen-Vacancy Centers inDiamond | |
| 柔软的3D打印肌肉超声仿体，具有结构可调的B模式回声强度 | Gillespie, S. | N/A | Soft, 3D printed muscle ultrasound phantom with structurally tunable B-mode echo intensity | |
| 使用InMoose进行批量转录组分析，InMoose是Python中的集成多组学开源环境 | Colange, M. | N/A | Bulk Transcriptomic Analysis with InMoose, the Integrated Multi-Omic Open-Source Environment in Python | |
| 解开细胞类型和状态转录程序的纠缠 | Wang, J. | N/A | Disentangling cell type and state transcriptional programs | |
| 不同条件下观察到的血栓蛋白质组含量：成功预测血栓淀粉样蛋白（原）性的作用 | Kell, D. B. | N/A | The proteome content of blood clots observed under different conditions: successful role in predicting clot amyloid(ogenicity) | |
| 芯片上流体诱导的血管重塑：对抗VEGF疗法的启示 | Mirzapour-Shafiyi, F. | N/A | Flow-Induced Vascular Remodeling On-Chip: Implications for Anti-VEGF Therapy | |
| 一个数学模型阐明了在增强子-基因预测中使用的ABC评分公式 | Nasser, J. | N/A | A mathematical model clarifies the ABC Score formula used in enhancer-gene prediction | |
| PD-L1表达受微小RNA加工、Wnt/β-catenin信号通路及化疗在Wilms瘤中的调控。 | Desai, K. | N/A | PD-L1 expression is mediated by microRNA processing, Wnt/β-catenin signaling, and chemotherapy in Wilms tumor | |
| 白血病突变蛋白PHF6和PHIP形成一个染色质复合物，抑制髓系白血病干细胞特性。 | Pawar, A. S. | N/A | Leukemia-mutated proteins PHF6 and PHIP form a chromatin complex that represses myeloid leukemia stemness | |
| 白血病突变蛋白PHF6和PHIP形成一种染色质复合物，抑制髓系白血病干细胞特性。 | Pawar, A. S. | N/A | Leukemia-mutated proteins PHF6 and PHIP form a chromatin complex that represses myeloid leukemia stemness | |
| β细胞是胰腺导管腺癌发展的关键驱动力 | Garcia, C. C. | N/A | Beta cells are essential drivers of pancreatic ductal adenocarcinoma development | |
| 高级别浆液性卵巢癌的单细胞空间图谱揭示了MHC II类分子作为空间肿瘤生态系统和临床结果的关键驱动因素 | Perez-Villatoro, F. | N/A | Single-cell spatial atlas of high-grade serous ovarian cancer unveils MHC class II as a key driver of spatial tumor ecosystems and clinical outcomes | |
| 知识图谱与机器学习助力神经系统疾病药物研究 | Menestrina, L. | N/A | Knowledge Graph and Machine Learning Help the Research of Drugs Aimed at Neurological Diseases | |
| 海湾战争疾病长期影响的表观遗传学研究 | Jones, B. C. | N/A | Epigenetic study of the long-term effects of Gulf War illness | |
| 接触钕会减弱胖头鲦鱼（Pimephales promelas）的低氧呼吸反应。 | Nykamp, N. M. | N/A | Exposure to neodymium blunts the hypoxic ventilatory response in fathead minnows (Pimephales promelas) | |
| AtSDR4L及其同源基因在多个种子部位促进种子到幼苗的转变 | Lu, B. | N/A | AtSDR4L and paralog promote seed-to-seedling transition in multiple seed compartments | |
| 通过局部润滑修复自身免疫损伤的角膜基质 | Efraim, Y. | N/A | Rebuilding the autoimmune-damaged corneal stroma through topical lubrication | |
| FCRL4和耗竭B细胞特征在肺癌浸润B细胞中 | Bryushkova, E. A. | N/A | FCRL4 and exhausted B cell signature in tumor infiltrating B cells from lung cancer | |
| 铬粒素A和卡特斯丁的缺失影响胰腺胰岛稳态、内分泌功能和神经递质 | Muntjewerff, E. M. | N/A | Loss of chromogranin A and catestatin affect pancreatic islet homeostasis, endocrine function, and neurotransmitters | |
| 在加拿大北极地区加强数据收集以获取海鸟兼捕信息，结果显示高度变异。 | Provencher, J. F. | N/A | Enhanced data collection in the Canadian Arctic for seabird bycatch information yields highly variable results | |
| 药物诱导的癌症持续者的最佳治疗方案涉及释放周期和中间药物剂量。 | Corigliano, M. | N/A | Optimal treatment for drug-induced cancer persisters involves release periods and intermediate drug doses | |
| 人类餐后代谢的DNA甲基化和基因表达轨迹 | Costeira, R. | N/A | DNA methylation and gene expression trajectories of human postprandial metabolism | |
| 宽频调谐与深部组织光谱检测的磷化铟纳米激光颗粒 | Cho, S. | N/A | Wideband Tuning and Deep-Tissue Spectral Detection of Indium Phosphide Nano-Laser Particles | |
| 可微育种：自动微分使得基于梯度的育种策略优化更加高效 | Hamazaki, K. | N/A | Differentiable breeding: Automatic differentiation enables efficient gradient-based optimization of breeding strategies | |
| PqsE在铜绿假单胞菌中作为群体感应转录因子RhlR的适配蛋白发挥作用。 | Tchadi, B. V. | N/A | PqsE acts as an adaptor protein for the quorum-sensing transcription factor RhlR in Pseudomonas aeruginosa | |
| 海藻糖支持埃及伊蚊细胞的生长，并调节基因表达和登革病毒复制。 | Conway, M. J. | N/A | Trehalose supports the growth of Aedes aegypti cells and modifies gene expression and dengue virus replication | |
| 通过固态核磁共振揭示白色念珠菌和白色念珠菌的细胞壁结构及棘球白素反应 | Dickwella Widanage, M. C. | N/A | Unveiling Cell Wall Structure and Echinocandin Response in Candida auris and Candida albicans via Solid-State NMR | |
| 盘基网柄菌-海分枝杆菌感染模型，是一种强大的抗感染化合物高通量筛选平台 | Nitschke, J. | N/A | The Dictyostelium discoideum - Mycobacterium marinum infection model, a powerful high throughput screening platform for anti-infective compounds | |
| 康泰唑地对感染脓肿分枝杆菌的小鼠和人类患者不同组织的分布情况 | Li, Q. | N/A | Distribution of contezolid in different tissues of mice and human patients infected with Mycobacterium abscessus | |
| 基于TurboID的邻近标记技术发现ABCF2为动物源性病原体多杀性巴氏杆菌的粘附受体 | Wang, F. | N/A | TurboID-based proximity labeling discovers ABCF2 as an adhesion receptor for the zoonotic pathogen Pasteurella multocida | |
| RNA N6-甲基腺苷修饰与猪繁殖与呼吸综合征病毒感染之间的动态相互作用 | Tong, J. | N/A | Dynamic interplay between RNA N6-methyladenosine modification and porcine reproductive and respiratory syndrome virus infection | |
| 即使存在沃尔巴克氏菌，蚊子的发育仍需要胞外微生物的参与。 | Serrato-Salas, J. | N/A | Extracellular microbes are required for mosquito development even in the presence of Wolbachia | |
| 原噬菌体的诱导有助于在肠道炎症期间改变肠道噬菌体组 | Sinha, A. | N/A | Prophage induction contributes to alterations in the gut phageome during intestinal inflammation | |
| 间歇性抑制性泊沙康唑疗法在减轻慢性恰加斯病实验模型中的心脏和消化道病理损害方面无效。 | Jayawardhana, S. | N/A | Intermittent suppressive posaconazole therapy is ineffective at mitigating cardiac and digestive tract pathologies in an experimental model of chronic Chagas disease | |
| 基于KP.2的单价mRNA疫苗能够显著增强对SARS-CoV-2的抗体反应。 | Wang, Q. | N/A | KP.2-based monovalent mRNA vaccines robustly boost antibody responses to SARS-CoV-2 | |
| 通过结合明确的交联信息，改进AlphaFold 3结构建模 | Kosinski, J. | N/A | Improving AlphaFold 3 structural modeling by incorporating explicit crosslinks | |
| 利用小鼠嗜性γ-逆转录病毒促进人类淋巴瘤细胞中的基因编辑 | Kumar, M. | N/A | Facilitating Gene Editing in Human Lymphoma Cells Using Murine Ecotropic γ-Retroviruses | |
| ΔNp63β的差异性转录活性由其同工型特异性的C端编码 | McCann, A. A. | N/A | Differential transcriptional activity of ΔNp63β is encoded by an isoform-specific C-terminus | |
| RNAi介导的HBV抗原关闭通过改变T细胞和B细胞的相互作用，增强了PEGIFNalpha的抗病毒免疫效果。 | Zai, W. | N/A | RNAi-mediated HBV antigen shutdown enhances the antiviral immune effects of PEGIFNalpha via altering T and B cell crosstalk | |
| 在钴胺素缺乏的条件下，硅藻生产钴胺素下配体，5,6-二甲基苯并咪唑的过程 | Gleason, A. K. | N/A | Production of the cobalamin lower ligand, 5,6-dimethylbenzimidazole, by a diatom under cobalamin-deplete conditions | |
| 基于土壤相关氨氧化菌的快速高通量筛选平台，用于生物硝化抑制剂的发现 | Kanellopoulos, A. E. | N/A | A fast-track, high-throughput screening platform for biological nitrification inhibitors discovery based on soil relevant ammonia oxidizing strains | |
| 土壤微生物在模拟根系分泌物中更偏好有机酸而非糖类。 | Wiesenbauer, J. | N/A | Soil microbes prefer organic acids over sugars in simulated root exudation | |
| 沙眼衣原体中含SWIB结构域的DNA拓扑异构酶I介导DNA松弛作用 | Shen, L. | N/A | The SWIB domain-containing DNA topoisomerase I of Chlamydia trachomatis mediates DNA relaxation | |
| # BioRxiv 2024-12-02 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 靶向噬菌体T4纳米颗粒逆转CD4+人类T细胞中的HIV-1潜伏期 | Batra, H. | N/A | Targeted Bacteriophage T4 Nanoparticles Reverse HIV-1 Latency in CD4+ Human T Cells | |
| 内体趋化因子受体信号复合体调控细胞迁移的中心机制 | Hahn, H. | N/A | Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration | |
| 撤回：类风湿性关节炎合并尿路感染患者中奇异变形杆菌分离株的免疫学参数 | Abdul, F. R. | N/A | WITHDRAWN: Immunological parameters of Proteus mirabilis isolates in Rheumatoid Arthritis patients with urinary tract infections | |
| 整合代谢规模和共存理论 | Saavedra, S. | N/A | Integrating metabolic scaling and coexistence theories | |
| 在人类癌细胞中，输入蛋白α在微核中积累，并与基因组不稳定性相关联。 | Miyamoto, Y. | N/A | Importin α accumulates in micronuclei and associates with genomic instability in human cancer cells | |
| 揭示早期人类B细胞淋巴发生调控机制及其在B细胞急性淋巴母细胞白血病发病机制中的意义 | Planell, N. | N/A | Uncovering the regulatory landscape of early human B-cell lymphopoiesis and its implications in the pathogenesis of B-cell acute lymphoblastic leukemia | |
| TEMPTED：纵向微生物组研究的时间感知降维方法 | Shi, P. | N/A | TEMPTED: Time-Informed Dimensionality Reduction for Longitudinal Microbiome Studies | |
| 后顶叶内侧皮层中的中尺度功能架构 | Hira, R. | N/A | Mesoscale functional architecture in medial posterior parietal cortex | |
| 通过内侧视前区异质神经元集群对女性性欲的射精后抑制 | Ishii, K. K. | N/A | Post-ejaculatory Inhibition of Female Sexual Drive via Heterogeneous Neuronal Ensembles in the Medial Preoptic Area | |
| 宽过渡态系综作为酶催化关键组分 | Jara, G. E. | N/A | Wide Transition-State Ensemble as Key Component for Enzyme Catalysis | |
| 通过三维几何形态测量法分析泰坦龙类（恐龙，蜥脚类）后肢形态的演化，揭示了宽步态姿势作为巨型化的适应性特征。 | Paramo Blazquez, A. | N/A | Evolution of hind limb morphology of Titanosauriformes (Dinosauria, Sauropoda) analyzed via 3D Geometric Morphometrics reveals wide-gauge posture as an exaptation for gigantism | |
| Vangl-Celsr极性复合物在胞内囊泡运输中的紊乱是导致气管-食管形态发生先天性异常的潜在原因。 | Edwards, N. A. | N/A | Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in trachea-esophageal morphogenesis | |
| 斑马鱼中的折叠与融合神经形成过程需要Vangl2蛋白的参与。 | MacGowan, J. | N/A | Fold-and-fuse neurulation in zebrafish requires Vangl2 | |
| USP7抑制促进老年骨质疏松小鼠早期骨整合 | Zhou, F. | N/A | USP7 Inhibition Promotes Early Osseointegration in Senile Osteoporotic Mice | |
| 在缺乏P物质和CGRPα信号的小鼠中，疼痛持续存在。 | MacDonald, D. I. | N/A | Pain persists in mice lacking both Substance P and CGRPα signaling | |
| 海马体中空间支架的情节记忆和联想记忆 | Chandra, S. | N/A | Episodic and associative memory from spatial scaffolds in the hippocampus | |
| 神经信号反卷积分析的可解释深度学习 | Tolooshams, B. | N/A | Interpretable deep learning for deconvolutional analysis of neural signals | |
| 选择性上皮表达KRASG12D突变在Oncopigs中驱动胰腺导管性肿瘤 | Jara, C. P. | N/A | Selective epithelial expression of KRASG12D mutation drives ductal pancreatic neoplasia in Oncopigs | |
| 扣带皮层塑造了出生后早期社会发声的发展 | Nagarajan, G. | N/A | Cingulate cortex shapes early postnatal development of social vocalizations | |
| 三重态态布居对GFP型荧光及光漂白的影响 | Byrdin, M. | N/A | Impact of Triplet State Population on GFP-type Fluorescence and Photobleaching | |
| 支配肝脏的迷走神经感觉神经元在喂食高脂饮食的小鼠中，对于脂肪肝和焦虑样行为的发展起着不可或缺的作用。 | Hwang, J. | N/A | Liver-innervating vagal sensory neurons play an indispensable role in the development of hepatic steatosis and anxiety-like behavior in mice fed a high-fat diet. | |
| 两个对抗性的基因调控网络在低温下驱动拟南芥根毛生长 | Urzua, T. | N/A | Two antagonistic gene regulatory networks drive Arabidopsis root hair growth at low temperature | |
| 一个包含超过34,000种脊椎动物的物种形成速率、不确定性以及存在-缺失矩阵的数据集 | Vasquez-Restrepo, J. D. | N/A | A dataset containing speciation rates, uncertainty, and presence-absence matrices for more than 34,000 vertebrate species | |
| 反馈在视觉工作记忆和长期记忆期间，均能调节皮层反应的空间调谐性。 | Woodry, R. | N/A | Feedback scales the spatial tuning of cortical responses during both visual working memory and long-term memory | |
| 在抗病毒反应中，Fish CDK2招募Dtx4通过泛素化降解TBK1 | Lu, L.-F. | N/A | Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response | |
| 腹侧苍白球的GABA能神经元在雄性大鼠中驱动摄食行为，但在雌性大鼠中则不然。 | Scott, A. | N/A | Ventral pallidal GABAergic neurons drive consumption in male, but not female rats | |
| 家犬驯化过程中的基因型和表型结果 | Sweetalana, | N/A | Genotypic and phenotypic consequences of domestication in dogs | |
| 有限的证据表明，概率性提示对光栅诱发的事件相关电位和方向解码性能有影响。 | den Ouden, C. | N/A | Limited evidence for probabilistic cueing effects on grating-evoked event-related potentials and orientation decoding performance | |
| 贝叶斯奥卡姆剃刀优化复杂系统模型的方法 | Wang, C. | N/A | Bayesian Occam's Razor to Optimize Models for Complex Systems | |
| 氘代谢成像表型通过葡萄糖转化动力学揭示小鼠胶质母细胞瘤的异质性 | Simoes, R. V. | N/A | Deuterium Metabolic Imaging Phenotypes Mouse Glioblastoma Heterogeneity Through Glucose Turnover Kinetics | |
| 新生儿血液中自闭症谱系障碍的性别特异性DNA甲基化特征 | Mouat, J. S. | N/A | Sex-specific DNA methylation signatures of autism spectrum disorder in newborn blood | |
| 坏死导致PolgD257A突变小鼠对结核分枝杆菌的易感性增加 | Mabry, C. J. | N/A | Necrosis drives susceptibility to Mycobacterium tuberculosis in PolgD257A mutator mice | |
| 实验诱导的疼痛和感觉异常对无疼痛年轻个体中袖带加压参数变化的响应不同 | Skalski, J. | N/A | Experimentally induced pain and paresthesia respond differently to parameter changes of cuff-based compression in pain-free young individuals | |
| 角质形成细胞向皮肤鳞状细胞癌的遗传进化 | Tandukar, B. | N/A | Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma | |
| 在早期儿童时期，皮层区域的一个子集表现出类似于成人的功能网络模式。 | Tu, J. C. | N/A | A Subset of Cortical Areas Exhibit Adult-like Functional Network Patterns in Early Childhood | |
| 微塑料作为抗菌素耐药性的新型促进剂：浓度、组成和尺寸对大肠杆菌多重耐药性的影响 | Gross, N. | N/A | Microplastics as a novel facilitator for antimicrobial resistance: Effects of concentration, composition, and size on Escherichia coli multidrug resistance | |
| 空间转录组分析揭示HDAC抑制通过调节小胶质细胞动态在小鼠中保护免受缺血性中风 | Jayaraj, K. | N/A | Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice | |
| 调节相互抑制的机制控制UNC-13的功能切换 | Liu, H. | N/A | Mechanism that regulates the mutual inhibition controls functional switch of UNC-13 | |
| 青春期对促肾上腺皮质激素释放因子受体1的拮抗作用会导致行为可塑性和杏仁核转录组特征的持续性、性别特异性变化。 | Martz, J. | N/A | Peripubertal antagonism of corticotropin-releasing factor receptor 1 results in sustained, sex-specific changes in behavioral plasticity and the transcriptomic profile of the amygdala | |
| 揭示具有微生物组相互作用特性的马铃薯品种，以实现可持续农业生产 | Zhao, T. | N/A | Unveiling the potato cultivars with microbiome interactive traits for sustainable agricultural production | |
| wtf杀手减数分裂驱动因子的功能性限制 | Srinivasa, A. N. | N/A | Functional constraints of wtf killer meiotic drivers | |
| 缺铁会导致大豆根部转录发生变化，进而破坏其耐旱性。 | Hasan, M. R. | N/A | Fe deficiency causes transcriptional shift in roots leading to disruption of drought tolerance in soybean | |
| 个人空间与群体灾难中的集体行为 | Lugo, I. | N/A | The personal space and the collective behavior of crowd disasters | |
| 味蕾中的死亡：死亡的味觉受体细胞被胶质样I型细胞吞噬 | Wilson, C. E. | N/A | Death in the taste bud: engulfment of dying taste receptor cells by glial-like Type I cells | |
| 社会结构对和尚鹦鹉发声灵活性的影响 | Smeele, S. Q. | N/A | The effect of social structure on vocal flexibility in monk parakeets | |
| 在高壁面剪切应力条件下，几种PfEBA和PfRH配体对恶性疟原虫疟疾血期生长至关重要。 | Kals, E. | N/A | Under conditions of high wall shear stress, several PfEBA and PfRH ligands are important for Plasmodium falciparum malaria blood-stage growth | |
| 催产素受体调控草原田鼠的滥交行为及发育 | Sharma, R. | N/A | Oxytocin receptor controls promiscuity and development in prairie voles | |
| 通过味觉受体检测细菌可启动细胞免疫反应 | Mazariegos, A. N. | N/A | Detection of bacteria through taste receptors primes the cellular immune response | |
| 果蝇在特征贫乏环境中的空间学习 | Chen, Y. | N/A | Spatial learning in feature-impoverished environments in Drosophila | |
| Lgl在有丝分裂退出时重置Par复合物膜加载，以实现不对称神经干细胞分裂 | LaFoya, B. | N/A | Lgl resets Par complex membrane loading at mitotic exit to enable asymmetric neural stem cell division | |
| 等压标记在MaxQuant中的更新 | Ferretti, D. | N/A | Isobaric labeling update in MaxQuant | |
| 照亮根土力学 | Le Houx, J. | N/A | Illuminating root-soil mechanics | |
| 顶枕叶伽马经颅交流电刺激对视觉空间注意任务中行为表现和神经活动的影响 | Zheng, T. | N/A | After-effects of Parieto-occipital Gamma Transcranial Alternating Current Stimulation on Behavioral Performance and Neural Activity in Visuo-spatial Attention Task | |
| 模拟欧洲范围内人类蜱传脑炎（TBE）发生概率的时空年度变化 | Dagostin, F. | N/A | Modeling spatio-temporal annual changes in the probability of human tick-borne encephalitis (TBE) occurrence across Europe | |
| 通过激光诱导的Soret效应实现亚稳态相分离液滴生成及长时间DNA富集 | Kobayashi, M. | N/A | Metastable phase-separated droplet generation and long-time DNA enrichment by laser-induced Soret effect | |
| 通过多模态方法分析亚麻荠和高粱对环境胁迫的响应特性 | Seitz, K. A. | N/A | Characterizing the Responses of Camelina and Sorghum to Environmental Stress through a Multi-Modal Approach | |
| 对多样性杂交小鼠研究中寿命的分析确定了多个与长寿相关的基因座 | Mullis, M. N. | N/A | Analysis of lifespan across Diversity Outbred mouse studies identifies multiple longevity-associated loci | |
| 委内瑞拉Llanos地区三种空中捕食蝙蝠的饮食与食性生态位划分 | Azofeifa Romero, Y. | N/A | Diet and trophic niche partitioning of three aerial hawking bat species in the Venezuelan Llanos | |
| 海拔和海洋屏障塑造了新西兰卡波卡波瓦伊（Uropetala）蜻蜓的分布、扩散和多样性 | Tolman, E. R. | N/A | Elevational and Oceanic Barriers Shape the Distribution, Dispersal and Diversity of Aotearoa's Kapokapowai (Uropetala) Dragonflies | |
| 基因组中转换突变频率高于颠换突变的证据：基于密度泛函理论的碱基对结合能计算 | Deka, N. | N/A | Higher frequency of transition mutation over transversion mutation in genomes: evidence from the binding energy calculation of base pairs using DFT | |
| 通过自然转化在人类肠道微生物组中测量微生物群落范围内的抗生素抗性传播 | Chowdhury, N. N. | N/A | Measuring Microbial Community-Wide Antibiotic Resistance Propagation via Natural Transformation in the Human Gut Microbiome | |
| 对Lasius蚁属的基因组数据进行去污染处理，以实现准确的物种划分和杂交检测 | Jecha, K. | N/A | Decontaminating genomic data for accurate species delineation and hybrid detection in the Lasius ant genus | |
| 体内网络活动的调节驱动了轴突起始段处轴-轴突突触的纳米尺度重构 | Compans, B. | N/A | In vivo modulation of network activity drives the nanoscale reorganisation of axo-axonic synapses at the axon initial segment | |
| 青春期和成年期怀孕期间的压力会影响下丘脑中的组蛋白乙酰化调节因子。 | Luther, L. A. | N/A | Stress during puberty and adulthood pregnancy impact histone acetylation regulators in the hypothalamus | |
| Lats1/2对于发育中的血管重塑和适应剪切应力的生物力学适应至关重要。 | Cowdin, M. A. | N/A | Lats1/2 are essential for developmental vascular remodeling and biomechanical adaptation to shear stress | |
| 古老社会染色体上超基因的重复进化 | Lajmi, A. | N/A | Repeated evolution of supergenes on an ancient social chromosome | |
| 森林不仅仅是树木：单倍型与推断的溯祖图 | Fritze, H. | N/A | A forest is more than its trees: haplotypes and inferred ARGs | |
| GluA1的细胞质尾部调控细胞内AMPA受体的运输以及对齿状回GABA能中间神经元的突触传递，调节对新奇刺激的反应 | Leana-Sandoval, G. | N/A | The GluA1 cytoplasmic tail regulates intracellular AMPA receptor trafficking and synaptic transmission onto dentate gyrus GABAergic interneurons, gating response to novelty | |
| 背外侧前额叶皮层细胞类型特异性增强子。 | He, J. | N/A | Cell Type Specific Enhancers for Dorsolateral Prefrontal Cortex. | |
| 转录调控元件的方向性 | Chen, Y. | N/A | Directionality of Transcriptional Regulatory Elements | |
| 电生理图作为一种功能性读数，用于评估果蝇黑腹果蝇神经退行性变模型中的神经元完整性。 | Manuel, N. | N/A | Electroretinograms as a functional readout of neuronal integrity in neurodegeneration models of Drosophila melanogaster | |
| 嘌呤能受体P2Y13调控室管膜下区成年神经干细胞的激活与分裂模式 | Paniagua-Herranz, L. | N/A | Purinergic Receptor P2Y13 Controls Activation and Mode of Division in Subependymal Adult Neural Stem Cells | |
| H5N1适应牛细胞的多基因决定因素 | Turnbull, M. L. | N/A | POLYGENIC DETERMINANTS OF H5N1 ADAPTATION TO BOVINE CELLS | |
| 分枝杆菌核小体相关蛋白NapM表现出应激诱导的隔膜定位，并调节细胞膜基因表达 | Milcarz, K. | N/A | The mycobacterial nucleoid-associated protein NapM exhibits stress-induced septal localization and modulates cell envelope gene expression | |
| 对涡虫再生特异性的比较分析揭示了轴向cWnt信号梯度对组织极性的贡献。 | Cleland, J. P. | N/A | A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient. | |
| 出生体重差异、基因表达与DNA甲基化：双胞胎表观遗传学研究的综述 | Wadji, D. L. | N/A | Birth weight discordance, gene expression, and DNA methylation: A review of epigenetic twin studies | |
| 相对于群体成员的空间位置会影响狐獴（Suricata suricatta）的体重增加 | Mosia, R. | N/A | Spatial position relative to group members affects weight gain in meerkats (Suricata suricatta) | |
| 光学层析成像技术在旋转驱动下重建多散射样品的3D运动和结构 | Moser, S. | N/A | Optical tomography reconstructing 3D motion and structure of multiple-scattering samples under rotational actuation | |
| 耶氏解脂耶氏酵母中基因编码报告基因的总体评价 | Zhang, H. | N/A | General assessment of genetically-encoded reporters in Yarrowia lipolytica | |
| Alevin-fry-atac 利用虚拟颜色实现单细胞ATAC-seq数据的快速且低内存消耗的基因组伪比对，从而进行准确的数据映射。 | Singh, N. P. | N/A | Alevin-fry-atac enables rapid and memory frugal mapping of single-cell ATAC-seq data using virtual colors for accurate genomic pseudoalignment | |
| extgfa：一种低内存的基因组图谱磁盘表示方法 | Dabbaghie, F. | N/A | extgfa: a low-memory on-disk representation of genome graphs | |
| 斜面显微镜中的主动远程聚焦稳定 | Nguyen, D. T. | N/A | Active Remote Focus Stabilization in Oblique Plane Microscopy | |
| Cetuximab-IRDye800偶联物在EGFR过表达肿瘤中的荧光和光声信号的时间动力学 | Saad, M. A. | N/A | Temporal dynamics of fluorescence and photoacoustic signals of a Cetuximab-IRDye800 conjugate in EGFR-overexpressing tumors | |
| 重新评估爱泼斯坦-巴尔病毒（EBV）与美国乳腺癌之间的关联 | Hu, C. C. | N/A | Reevaluating the Association Between Epstein-Barr Virus (EBV) and Breast Cancer in the United States | |
| 通过sEV液体活检揭示miR-451a和miR-142-3p作为非小细胞肺癌的预后标志物 | Burdiel Herencia, M. | N/A | Unveiling miR-451a and miR-142-3p as Prognostic Markers in NSCLC via sEV Liquid Biopsy | |
| 正电子发射断层扫描（PET）示踪剂能够成像高CD73表达的癌症。 | Dobelmann, C. | N/A | Positron emission tomography (PET) tracer enables imaging of high CD73 expression in cancer | |
| 细胞自主性游离脂肪酸受体4-ChemR23信号级联保护心肌细胞免受缺血损伤 | Puccini, S. | N/A | A Cell Autonomous Free fatty acid receptor 4 - ChemR23 Signaling Cascade Protects Cardiac Myocytes from Ischemic Injury | |
| 在Physcomitrella光生物反应器中生产蜘蛛丝蛋白的重组生产 | Ramezaniaghdam, M. | N/A | Recombinant production of spider silk protein in Physcomitrella photobioreactors | |
| 产后第一年内存在亲子关系障碍的母亲的情绪处理：一项改编的fMRI情绪GoNoGo任务的结果 | Eckstein, M. | N/A | Emotion processing in mothers with bonding disorder during the first year postpartum: Results of an adapted fMRI emotional GoNoGo Task | |
| 短暂的新生儿视觉剥夺对人类腹侧枕颞皮层发育的影响 | Mattioni, S. | N/A | Impact of a transient neonatal visual deprivation on the development of the ventral occipito-temporal cortex in humans | |
| LRRK2 G2019S突变在感染性结肠炎模型中激发了细胞内在的中性粒细胞效应功能增强和肠道炎症 | Pei, J. | N/A | LRRK2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis | |
| 红李（Leea rubra Blume）抗氧化、抗糖尿病和抗菌活性的体外研究 | Mai, H. V. | N/A | In Vitro Studies of Antioxidant, Antidiabetic, and Antibacterial Activities of Leea rubra Blume | |
| 在小鼠和人类中移植后高度功能性效应CD8+ T细胞程序的鉴定 | Cohen, G. S. | N/A | Identification of a Highly Functional Effector CD8+ T Cell Program After Transplantation in Mice and Humans | |
| 欧洲亚型蜱传脑炎病毒在韩国的兴起（2005-2014年）可能与人类活动有关 | Kovalev, S. Y. | N/A | European Subtype Tick-Borne Encephalitis Virus Emergence In South Korea (2005 - 2014) Can Be Associated With Human Activity | |
| TTF2通过将TRAIP泛素连接酶与Pol epsilon耦合，驱动有丝分裂复制体的解体和MiDAS。 | FUJISAWA, R. | N/A | TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Pol epsilon | |
| 细胞类型特异性体内蛋白质组与多拷贝突变型甲硫氨酰tRNA合成酶小鼠品系 | Schuman, E. M. | N/A | Cell type-Specific In Vivo Proteomes with a Multi-copy Mutant Methionyl t-RNA Synthetase Mouse Line | |
| 利用原子力显微镜绘制海鞘胚胎在卵裂阶段的单细胞流变学图谱 | Kotani, T. | N/A | Mapping single-cell rheology of ascidian embryos in the cleavage stages using AFM | |
| 皮质微管作为模板，组织了胞吐作用的纳米级图案化。 | Lindeboom, J. | N/A | Cortical microtubules act as a template to organize nano-scale patterning of exocytosis | |
| 两种新型红色FRET ERK生物传感器，波长范围为670-720纳米。 | DeCuzzi, N. L. | N/A | Two Novel Red-FRET ERK Biosensors in the 670-720nm Range. | |
| 双皮质素结构域蛋白ZYG-8对微管的硬化作用有助于在秀丽隐杆线虫合子分裂过程中纺锤体的定向 | Cueff, L. | N/A | Microtubule stiffening by doublecortin-domain protein ZYG-8 contributes to spindle orientation during C. elegans zygote division | |
| Rbfox1和mir-33调控JAK/STAT信号在果蝇成体肌生成中的多效性作用 | Mukherjee, A. | N/A | Rbfox1 and mir-33 regulate pleiotropic roles of JAK/STAT signalling during adult myogenesis in Drosophila melanogaster | |
| 不同的细胞和分子机制导致几丁质沉积，这有助于D. melanogaster中两种几丁质合成酶的特异性。 | Bertran-Mas, J. | N/A | Different cellular and molecular mechanisms of chitin deposition contribute to the specificity of the two chitin synthases in D. melanogaster. | |
| 饮食中的余甘子（印度醋栗，Amla）可提高果蝇模型中早期营养不良的生育力和抗氧化应激能力。 | Padmaraj, P. | N/A | Dietary Phyllanthus emblica L. (Indian gooseberry, Amla) improves fecundity and resistance to oxidative stress in a Drosophila melanogaster model of early-life malnutrition. | |
| 海洋硅藻热耐受性的演变：热胁迫下的代谢策略。 | Aranguren-Gassis, M. | N/A | Evolution of thermal tolerance in marine diatoms: Metabolic strategies under heat stress. | |
| 细胞对冷冻-解冻应激产生类似静止状态的趋同适应 | Tvishamayi, C. | N/A | Convergent cellular adaptation to a quiescence-like state in response to freeze-thaw stress | |
| 近似贝叶斯计算支持了人类囊胚阶段胚胎中染色体嵌合现象的高发生率。 | Yang, Q. | N/A | Approximate Bayesian computation supports a high incidence of chromosomal mosaicism in blastocyst-stage human embryos | |
| 鉴定并分析扁虫Hofstenia miamia中的微小RNA的发育特征 | Duan, Y. | N/A | Identification and developmental profiling of microRNAs in the acoel worm Hofstenia miamia | |
| Indel驱动的刀豆氨酸tRNA编辑去乙酰酶CtdA的进化 | Mayans, O. | N/A | Indel-driven evolution of the canavanine tRNA-editing deacetylase enzyme CtdA | |
| 无标记下使用全息断层显微镜和U-Net对内皮细胞线粒体进行可视化与分割 | Michael, R. | N/A | Label-Free Visualization and Segmentation of Endothelial Cell Mitochondria Using Holotomographic Microscopy and U-Net | |
| 在人类肾脏中整合空间多重蛋白质成像和转录组学，追踪近端小管再生潜力的时间线 | Asghari, M. | N/A | Integration of spatial multiplexed protein imaging and transcriptomics in the human kidney tracks the regenerative potential timeline of proximal tubules | |
| 多特征AI集成与投票系统在MAPKAPK2抑制剂发现中的优化 | Chen, H. | N/A | Optimization of a Multi-Feature AI Ensemble and Voting System for MAPKAPK2 Inhibitor Discovery | |
| 使用反事实的定量归因 | Adjavon, D.-Y. | N/A | Quantitative Attributions with Counterfactuals | |
| 涂层刷的电荷分布驱动染色体间的吸引力 | Sorichetti, V. | N/A | Charge distribution of coating brush drives inter-chromosome attraction | |
| 使用冷冻电子断层扫描技术对染色质生物分子凝聚物进行定量空间分析 | Zhou, H. | N/A | Quantitative Spatial Analysis of Chromatin Biomolecular Condensates using Cryo-Electron Tomography | |
| 黏附-悬浮转变促进黑色素瘤的转移扩散 | Lee, D. K. | N/A | Adherent-to-suspension transition promotes melanoma metastatic dissemination | |
| 林奇综合征相关尿路上皮癌中受限的超突变及TERT启动子突变的缺失 | Nikkola, J. | N/A | Constrained hypermutation and absence of TERT promoter mutations in Lynch syndrome-associated urothelial cancer | |
| 一种新型RyR2选择性稳定剂可预防和改善应激诱导的室性心动过速中的严重心律失常 | Kurebayashi, N. | N/A | A novel RyR2-selective stabilizer prevents and ameliorates severe arrhythmias in stress-induced ventricular tachycardia | |
| 大肠杆菌应激反应调节子中的动态异质性介导基因激活和抗菌肽耐受性 | Blassick, C. M. | N/A | Dynamic heterogeneity in an E. coli stress response regulon mediates gene activation and antimicrobial peptide tolerance | |
| 一种多层次形式体系，用于捕捉上皮-间质可塑性中混合表型的特征 | Hari, K. | N/A | A multi-level formalism to capture the characteristics of hybrid phenotypes in Epithelial-Mesenchymal Plasticity | |
| fluxTrAM：将基于示踪剂的代谢组学数据整合到原子分辨率的基因组规模代谢网络中，用于代谢通量分析 | Huang, L. | N/A | fluxTrAM: Integration of tracer-based metabolomics data into atomically resolved genome-scale metabolic networks for metabolic flux analysis | |
| 非甾体抗炎药物的代谢组学反应 | Ghosh, S. | N/A | Metabolomic Response to Non-Steroidal Anti-Inflammatory Drugs | |
| 规范模型揭示了青春期前儿童在精神病理学维度上存在不同的皮层异常 | Deng, Q. | N/A | Normative models reveal distinct cortical abnormalities to dimensions of psychopathologies in preadolescents | |
| 干扰素-γ通过IRF1对炎症NF-κB靶基因的表观遗传调控 | Mishra, B. | N/A | Epigenetic Regulation of Inflammatory NF-κB Target Genes by IFN-γ via IRF1 | |
| Zfh1与Nau之间的相互作用通过一个由mir-9a介导的负反馈回路，在果蝇（Drosophila melanogaster）中调控Rbfox1及其靶标Stat92E的肌源性阶段依赖性表达。 | Mukherjee, A. | N/A | The interplay between Zfh1 and Nau orchestrates the myogenic stage-dependent expression of Rbfox1 and its target Stat92E via a mir-9a-mediated negative feedback loop in Drosophila melanogaster | |
| 从讣告中识别家庭结构并将其与电子健康记录中的患者进行匹配。 | Mayer, J. G. | N/A | Identifying Family Structures from Obituaries and Matching them to Patients in an Electronic Heath Record. | |
| 深度学习与浅层混合纳米孔-Illumina测序用于经济实惠且准确的检测种系变异。 | Gambardella, G. | N/A | Deep-leaning and shallow hybrid Nanopore-Illumina sequencing for affordable and accurate detection of germline variants. | |
| CEACAM1通过脂噬依赖的铁死亡介导心房颤动，靶向ABCA1 | Hu, W.-w. | N/A | CEACAM1 Targets ABCA1 to Mediate Atrial Fibrillation via Lipophagy-Dependent Ferroptosis | |
| 独特的最小临床截短突变对BRCA1相互作用组的不同重塑 | Chen, J. | N/A | Differential Remodeling of the BRCA1 Interactome by a Unique Minimal Clinical Truncation Mutation | |
| 从质谱指纹图谱进行基因本体的大规模预测揭示了新的代谢基因功能 | Vavricka, C. | N/A | Genome-scale prediction of gene ontology from mass fingerprints reveals new metabolic gene functions | |
| Cycledesigner 利用 RFdiffusion 和 HighFold 设计针对特定目标的环肽结合剂 | Zhang, C. | N/A | Cycledesigner Leveraging RFdiffusion and HighFold to Design Cyclic Peptide Binders for Specific Targets | |
| 古基因组学支持东地中海和西地中海印欧语言之间存在深远分化。 | Yediay, F. E. | N/A | Ancient genomics support deep divergence between Eastern and Western Mediterranean Indo-European languages | |
| 烟草烟雾改变了肺腺癌中突变、选择和上位性的格局 | Dasari, K. | N/A | Tobacco smoke alters the landscape of mutation, selection, and epistasis in lung adenocarcinoma | |
| NEFFy：一种用于计算有效序列数量的多功能工具 | Haghani, M. | N/A | NEFFy: A Versatile Tool for Computing the Number of Effective Sequences | |
| 在非小细胞肺癌中，细胞间的融合在药物选择下赋予了适应性优势 | Shultes, P. V. | N/A | Cell-Cell Fusion in NSCLC Confers a Fitness Benefit Under Drug Selection | |
| 长期高温影响甘蓝型油菜种子的成熟度和种皮完整性 | Prabhullachandran, U. | N/A | Long-term high temperatures affect seed maturation and seed coat integrity in Brassica napus | |
| 单细胞海洋捕食者的全球种群结构 | Latorre, F. | N/A | Global population structure of a unicellular marine predator | |
| 网络结构和适应性觅食对物种丰富的植物-传粉者群落传粉服务的影响 | Valdovinos, F. S. | N/A | Effect of network structure and adaptive foraging on pollination services of species-rich plant-pollinator communities | |
| 研究设计和在生物银行规模数据集中对有害罕见变异的采样 | Steiner, M. C. | N/A | Study design and the sampling of deleterious rare variants in biobank-scale datasets | |
| 拟谷盗近缘物种基因组中卫星DNA的动态演化 | Veseljak, D. | N/A | Dynamic evolution of satellite DNAs drastically differentiates the genomes of Tribolium sibling species | |
| 从长读取重叠区域估计基因组大小 | Hall, M. B. | N/A | Genome size estimation from long read overlaps | |
| 人脑和猴脑中的连接性：探讨穹窿在轻度认知障碍和阿尔茨海默病中的因果作用 | Pelekanos, V. | N/A | Connectivity in the human and the monkey brain probes causal involvement of the fornix in Mild Cognitive Impairment and Alzheimer's Disease | |
| 在小鼠阿尔茨海默病、动脉粥样硬化及阿尔茨海默病合并动脉粥样硬化模型中表征血管功能 | Eyre, B. | N/A | Characterizing vascular function in mouse models of Alzheimer's disease, atherosclerosis, and mixed Alzheimer's and atherosclerosis | |
| 周围炎症刺激导致小胶质细胞吞噬谷氨酸能输入，并降低伏隔核D1中型多棘神经元的兴奋性。 | Nakajima, S. | N/A | Microglial engulfing of glutamatergic inputs and diminished excitability of D1 medium spiny neurons of the nucleus accumbens by peripheral inflammatory insult | |
| 突触乙酰胆碱通过烟碱受体在基底外侧杏仁核中诱导出尖波涟漪。 | Bratsch-Prince, J. X. | N/A | Synaptic acetylcholine induces sharp wave ripples in the basolateral amygdala through nicotinic receptors | |
| 异步亚基转换先于乙酰胆碱受体激活 | Thompson, M. J. | N/A | Asynchronous subunit transitions precede acetylcholine receptor activation | |
| MEG信号揭示了顶叶前额叶皮层中手臂姿势编码和内在运动计划的存在。 | Blohm, G. | N/A | MEG signals reveal arm posture coding and intrinsic movement plans in parietofrontal cortex | |
| 用于连续测量亚100纳摩尔尼古丁的荧光蛋白生物传感器的水凝胶封装 | Nichols, A. L. | N/A | Hydrogel encapsulation of a designed fluorescent protein biosensor for continuous measurements of sub-100 nanomolar nicotine | |
| 综合现象学和脑连接性研究表明，在高级冥想（如禅那）中，非线性处理发生了变化。 | Potash, R. M. | N/A | Integrated phenomenology and brain connectivity demonstrate changes in nonlinear processing in jhana advanced meditation | |
| 过度活跃的神经网络促进阿尔茨海默病小鼠模型中的tau蛋白扩散 | Barbour, A. J. | N/A | Hyperactive neuronal networks facilitate tau spread in an Alzheimer's disease mouse model | |
| ASH1L通过动态调节染色质环境调控人类神经元结构与功能 | Jhanji, M. | N/A | Dynamic Regulation Of The Chromatin Environment By ASH1L Modulates Human Neuronal Structure And Function | |
| 对埃及伊蚊基因表达的分析表明，蚊子发育早期阶段的遗传调控发生了变化。 | dos Santos, R. C. | N/A | Analysis of gene expression in Aedes aegyptisuggests changes in early genetic control of mosquito development | |
| 双语接触与性别塑造婴儿对语音特征大脑反应的发展轨迹 | Puertollano, M. | N/A | Bilingual Exposure and Sex Shape Developmental Trajectories of Brain Responses to Speech-Sound Features in Infants | |
| PDGFRα+间充质基质细胞在前列腺发育过程中促进上皮谱系的形成 | Maiti, D. | N/A | PDGFRα+ Mesenchymal Stromal Cells Contribute to Epithelial Lineages during Prostate Development | |
| 通过dPGC1控制线粒体动力学限制了Yorkie诱导的果蝇致癌性生长 | Sew, W. Q. G. | N/A | Control of mitochondrial dynamics by dPGC1 limits Yorkie-induced oncogenic growth in Drosophila | |
| 果蝇对细菌肽聚糖的感知反应整合了正负信号 | Montanari, M. | N/A | Drosophila's sensory responses to bacterial peptidoglycan integrates positive and negative signals | |
| 海洋蠕虫Capitella teleta对神经化学操纵非常敏感，这一发现是通过一种新型的高通量行为工具揭示的。 | Hendershot, M. | N/A | The marine worm Capitella teleta is sensitive to neurochemical manipulation, as revealed via a novel high-throughput behavioural tool | |
| 雌性虎皮鹦鹉更倾向于选择与自己觅食技能不同的雄性。 | Zou, Y. | N/A | Female budgerigars prefer males with foraging skills that differ from their own | |
| 前额叶星形胶质细胞的过度激活通过中枢犬尿氨酸的代谢途径损害认知 | Beilmann, V. | N/A | Overactivation of prefrontal astrocytes impairs cognition through the metabolic pathway of central kynurenines | |
| 静息态fMRI去噪流程在运动校正和行为预测中的有效性。 | Pavlovich, K. | N/A | The efficacy of resting-state fMRI denoising pipelines for motion correction and behavioural prediction. | |
| 解码支持层次任务泛化的任务表示 | Lee, W. | N/A | Decoding task representations that support generalization in hierarchical task | |
| 不同强度单侧手握疲劳对双侧运动的影响 | Knorz, A. L. | N/A | The effects of varying intensities of unilateral handgrip fatigue on bilateral movement | |
| 早期生活压力暴露的相似性与成年早期神经表征的相似性相关 | Ilomäki, M. | N/A | Similarity in Early Life Stress Exposure is Associated with Similarity in Neural Representations in Early Adulthood | |
| 自主运动在大脑大静脉中引起早期且远端的血流动力学下降 | Eyre, B. | N/A | Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins | |
| ARBEL：一种基于光学的图像分析机器学习工具，用于三维疼痛行为的自动分类 | Barkai, O. | N/A | ARBEL: A Machine Learning Tool with Light-Based Image Analysis for Automatic Classification of 3D Pain Behaviors | |
| VGCC辅助亚基α2δ1是一种与细胞外GluA1相互作用的蛋白质，并调节长时程增强（LTP）、空间记忆和癫痫易感性。 | Leana-Sandoval, G. | N/A | The VGCC auxiliary subunit α2δ1 is an extracellular GluA1 interactor and regulates LTP, spatial memory, and seizure susceptibility | |
| 重复性脑熵（BEN）在沉思期间的改变 | Lu, J. | N/A | Reproducible Brain Entropy (BEN) Alterations During Rumination | |
| 纹状体星形胶质细胞影响多巴胺动态和行为状态转换 | Lazaridis, I. | N/A | Striatal Astrocytes Influence Dopamine Dynamics and Behavioral State Transitions | |
| 人类在感知推断中使用了对听觉空间和时间不确定性的过度自信估计。 | Hong, F. | N/A | Humans use overconfident estimates of auditory spatial and temporal uncertainty for perceptual inference | |
| “多少才算足够？”——儿童自然fMRI功能连接可靠性的考量 | Rai, S. S. | N/A | How much is 'enough'? Considerations for functional connectivity reliability in pediatric naturalistic fMRI | |
| 早期生活逆境改变成年期腹侧被盖区神经元：对压力增加和强迫行为易感性的神经机制的启示 | Gugula, A. | N/A | Early-life adversity alters adult nucleus incertus neurons: implications for neuronal mechanisms of increased stress and compulsive behavior vulnerability | |
| RIG-I介导的神经元特异性I型干扰素信号在FUS-ALS中诱导神经退行性变，并为（FUS-）ALS提供了新的生物标志物驱动的个性化治疗选择。 | Naumann, M. | N/A | RIG-I mediated neuron-specific IFN type 1 signaling in FUS-ALS induces neurodegeneration and offers new biomarker-driven individualized treatment options for (FUS-)ALS | |
| KIF3C在调控小脑发育过程中Bergmann胶质细胞密度和模式形成中发挥作用 | Waas, B. | N/A | KIF3C Regulates Bergmann Glia Density and Patterning during Cerebellar Development | |
| 由于产前大麻二酚暴露导致的焦虑发展轨迹的性别特异性破坏 | Iezzi, D. | N/A | Sex-specific disruptions in the developmental trajectory of anxiety due to prenatal cannabidiol exposure | |
| 人类听觉大脑中时间整合的信号：心理洞察、脑电图证据及临床应用 | Xu, H. | N/A | A signal of temporal integration in the human auditory brain: psychological insights, EEG evidence, and clinical application | |
| 人类听觉大脑中的时间整合信号：心理学洞察、脑电图证据及临床应用 | Xu, H. | N/A | A signal of temporal integration in the human auditory brain: psychological insights, EEG evidence, and clinical application | |
| KlebPhaCol：一个由社区驱动的克雷伯氏菌研究资源发现了一种与人类肠道相关的新型肠道噬菌体目。 | Rothschild-Rodriguez, D. | N/A | KlebPhaCol: A community-driven resource for Klebsiella research identified a novel gut phage order associated with the human gut | |
| 利用孕早期阴道微生物群早期预测子痫前期 | Kindschuh, W. F. | N/A | Early prediction of preeclampsia using the first trimester vaginal microbiome | |
| 在丝状蓝藻中，氰外排酶B对于运动性、生物膜形成和藻青素生产是必不可少的。 | Parrett, G. | N/A | Cyanoexosortase B is essential for motility, biofilm formation and scytonemin production in a filamentous cyanobacterium | |
| 绘制犬类微生物组图谱：来自狗衰老项目的见解 | Bamberger, T. | N/A | Mapping the canine microbiome: Insights from the Dog Aging Project | |
| 小鼠长期肠道衣原体定植期间肠道屏障破坏的洞察：单细胞转录组学方法 | Tian, Q. | N/A | Insights into Intestinal Barrier Disruption During Long-Term Gut Chlamydia Colonization in Mice: A Single-Cell Transcriptomic Approach | |
| 研究辣椒素在通过细胞外囊泡促进柯萨奇病毒B3传播中的潜在作用 | Chatterjee, S. | N/A | Investigating the potential role of capsaicin in facilitating the spread of coxsackievirus B3 via extracellular vesicles | |
| 沿海植物的根系有助于稳定海洋藻类固定的碳。 | Hellige, I. | N/A | Roots of coastal plants stabilize carbon fixed by marine algae | |
| 识别基孔肯雅病毒nsP2 ATPase的抑制剂 | Navarro, H. | N/A | Identification of Inhibitors of Chikungunya virus nsP2 ATPase | |
| 整合应激反应沉默的分子基础 | Yang, Z. | N/A | The molecular basis of integrated stress response silencing | |
| 人类线粒体RNA聚合酶结构揭示转录起始位点和滑移机制 | Shen, J. | N/A | Human mitochondrial RNA polymerase structures reveal transcription start-site and slippage mechanism | |
| 转录因子GATA1识别RNA的独特机制 | Ugay, D. A. | N/A | A distinct mechanism of RNA recognition by the transcription factor GATA1 | |
| 先进的肽纳米颗粒能够实现对多种细胞类型进行强大且高效的基因编辑器递送。 | Gustafsson, O. | N/A | Advanced Peptide Nanoparticles Enable Robust and Efficient delivery of gene editors across cell types | |
| SARS-CoV-2 N蛋白的动态集合揭示了头对头卷曲螺旋驱动的寡聚化和相分离现象 | Hernandez, G. G. | N/A | Dynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation | |
| 靶向内质网应激和亚硝基氧化还原失衡在神经内分泌前列腺癌中的治疗作用：一氧化氮的作用 | FIRDAUS, F. | N/A | Targeting Endoplasmic Reticulum Stress and Nitroso-Redox Imbalance in Neuroendocrine Prostate Cancer: The Therapeutic Role of Nitric Oxide | |
| 发散思维和创造性人格对多米尼加大学科学产出和创新质量的影响 | Montano Medina, G. A. | N/A | The Influence of Divergent Thinking and Creative Personality on the Quality of Scientific Production and Innovation in a Dominican University | |
| 通过纳米孔测序和引导学习实现非天然碱基的直接高通量解卷积 | Perez, M. | N/A | Direct high-throughput deconvolution of unnatural bases via nanopore sequencing and bootstrapped learning | |
| 使用Orbitrap Ascend Tribrid质谱仪对亲和纯化蛋白复合物进行FAIMS分析 | Goswami, P. | N/A | Analysis of FAIMS for the Study of Affinity-Purified Protein Complexes Using the Orbitrap Ascend Tribrid Mass Spectrometer | |
| 环境暴露和家族背景会改变SARS-CoV-2感染后神经病理学和炎症的诱发。 | Chatterjee, D. | N/A | Environmental exposures and familial background alter the induction of neuropathology and inflammation after SARS-CoV-2 infection. | |
| L-天冬酰胺酶治疗在T细胞依赖的B细胞激活模型中，对非恶性B细胞产生可逆的免疫调节和免疫抑制效应。 | Hadzic, A. | N/A | L-Asparaginase treatment induces reversible immunoregulatory and immunosuppressive effects in non-malignant B cells in a model of T-cell dependent B cell activation | |
| 根据临床表型分层的系统性硬化症患者循环浆细胞样树突状细胞的独特代谢特征 | Ferreira, B. H. | N/A | Distinct metabolic profiles of circulating plasmacytoid dendritic cells in systemic sclerosis patients stratified by clinical phenotypes | |
| 土壤细菌中性脂质脂肪酸：碳储存还是腐殖质标记？ | Gorka, S. | N/A | Soil bacterial neutral lipid fatty acids: Markers for carbon storage or necromass? | |
| 扩展CarD相互作用网络：CrsL是耻垢分枝杆菌中的一种新型转录因子 | Shoman, M. | N/A | Expanding the CarD interaction network: CrsL is a novel transcription factor in Mycobacterium smegmatis | |
| 全基因组测序揭示Enterobacter hormaechei为尼日利亚西南部六家三级护理医院的关键血流病原体。 | Oni, F. I. | N/A | Whole genome Sequencing Reveals Enterobacter hormaechei as a key Bloodstream Pathogen in six tertiary care hospitals in southwestern Nigeria. | |
| 利用两种和三种物种的FliC嵌合体拯救细菌运动性 | Scadden, J. | N/A | Rescue of bacterial motility using two and three-species FliC chimeras | |
| 利用两种和三种物种的FliC嵌合体拯救细菌运动性 | Scadden, J. | N/A | Rescue of bacterial motility using two and three-species FliC chimeras | |
| 小龙虾病原菌Candidatus Paracoxiella cheracis n.g. n.sp.的完整基因组序列为我们深入了解其致病机制及Coxiellaceae科的系统发育关系提供了重要线索。 | Ingle, D. J. | N/A | The complete genome sequence of the crayfish pathogen Candidatus Paracoxiella cheracis n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family | |
| 小龙虾病原菌Candidatus Paracoxiella cheracis n.g. n.sp.的完整基因组序列揭示了其致病机制及Coxiellaceae科的系统发育关系。 | Ingle, D. J. | N/A | The complete genome sequence of the crayfish pathogen Candidatus Paracoxiella cheracis n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family | |
| 在铀污染的含水层中，微生物群落的多样性适度下降，组成变化显著 | Fan, Y. | N/A | Modest functional diversity decline and pronounced composition shifts of microbial communities in a uranium-contaminated aquifer | |
| 金黄色葡萄球菌POT转运蛋白DtpT在人巨噬细胞内二/三肽摄取和谷胱甘肽利用中的独特作用 | Khan, I. | N/A | Distinct roles for the Staphylococcus aureus POT transporter DtpT in di/tripeptide uptake and glutathione utilisation inside human macrophages | |
| 针对TREM2-TYROBP跨膜结合的药物筛选 | Cobas-Carreno, M. | N/A | Drug screening targeting TREM2-TYROBP transmembrane binding | |
| 更大的宿主影响和杂交性：入侵海藻宿主如何优于同时存在的本地物种 | Ghotbi, M. | N/A | Greater host influence and promiscuity: How an invasive seaweed host has advantages over co-occurring natives | |
| 土地覆盖和气候变化对印度鸟类栖息地的影响 | Diengdoh, V. L. | N/A | Impact of land cover and climate change on habitat of Indian birds | |
| 在波动环境中可塑性和性状置换的演变 | Chevin, L.-M. | N/A | Evolution of plasticity and character displacement in a fluctuating environment | |
| 四倍体黑莓刺的遗传控制 | Johns, C. A. | N/A | Genetic Control of Prickles in Tetraploid Blackberry | |
| GAGER：基因调控网络辅助基因表达恢复 | Chowdhury, M. Z. U. S. | N/A | GAGER: gene regulatory network assisted gene expression restoration | |
| 人β细胞中甘氨酸受体活性的分子相关性 | Gomes, A. S. | N/A | Molecular Correlates of Glycine Receptor Activity in Human β Cells | |
| 人类诱导多能干细胞（iPSCs）中染色体12三体性激增的起源 | Narozna, M. | N/A | Origin of Chromosome 12 Trisomy Surge in Human Induced Pluripotent Stem Cells (iPSCs) | |
| 热诱导的磷脂酰丝氨酸变化驱动HSPA1A在质膜的定位 | Low, J. | N/A | Heat-Induced Phosphatidylserine Changes Drive HSPA1A's Plasma Membrane Localization | |
| 葡萄糖-6-磷酸酶对于果蝇精子的能量代谢、运动能力及生育力是必需的。 | Hedjazi, S. | N/A | Glucose-6-phosphatase is required for sperm energy metabolism, motility and fertility in Drosophila | |
| 三维hiPSC-心脏微组织工业化用于高通量心脏安全性和药物发现筛选 | de Korte, T. | N/A | Industrialization of three-dimensional hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening | |
| 成人口腔的免疫调节结构 | Fernandes Matuck, B. | N/A | The Immunoregulatory Architecture of the Adult Oral Cavity | |
| Retromer对抗阿片类药物引起的μ阿片受体下调 | Dagunts, A. | N/A | Retromer Opposes Opioid-Induced Downregulation of the Mu Opioid Receptor | |
| 多梳抑制复合物2促进动脉粥样硬化斑块的脆弱性 | Joshi, D. | N/A | Polycomb Repressive Complex 2 promotes atherosclerotic plaque vulnerability | |
| 沿着和逆着受限的粘附梯度进行单细胞迁移 | Fortunato, I. C. | N/A | Single cell migration along and against confined haptotactic gradients | |
| 光遗传学诱导的微管乙酰化揭示了定向细胞迁移中肌动蛋白-微管交叉对话的分子动力学 | Deb Roy, A. | N/A | Optogenetically Induced Microtubule Acetylation Unveils the Molecular Dynamics of Actin-Microtubule Crosstalk in Directed Cell Migration | |
| 通过mRNA定位控制上皮组织结构 | Mason, D. E. | N/A | Control of Epithelial Tissue Organization by mRNA Localization | |
| BECLIN-1 通过调节内吞运输、F-肌动蛋白组织和溶酶体功能，对维持胃肠道上皮完整性至关重要。 | Juliani, J. | N/A | BECLIN-1 is Essential for the Maintenance of Gastrointestinal Epithelial Integrity by Regulating Endocytic Trafficking, F-actin Organization and Lysosomal Function | |
| Erk1/2对Pak1的磷酸化作用于细胞迁移需要Arl4D作为支架蛋白的参与。 | Chang, T.-W. | N/A | The phosphorylation of Pak1 by Erk1/2 for cell migration requires Arl4D acting as a scaffolding protein | |
| MAGI2的调控及其在足细胞病变诊断中的应用 | Siegerist, F. | N/A | The Regulation of MAGI2 and its Diagnostic Application in Podocytopathies | |
| 秀丽隐杆线虫的huntingtin蛋白，即htt-1，在应激条件下能够促进强效的自噬诱导和生存。 | Chung, C. H. | N/A | C. elegans huntingtin, htt-1, promotes robust autophagy induction and survival under stress conditions | |
| # BioRxiv 2024-12-01 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 惩罚风险任务：在小鼠进行目标导向行为时监测其焦虑状态 | Parker, K. E. | N/A | Punishment Risk Task: Monitoring anxiogenic states during goal directed actions in mice | |
| 肿瘤相关巨噬细胞的抗原呈递促使肿瘤浸润T细胞从原始的耗竭状态转变为终末耗竭状态。 | Waibl Polania, J. | N/A | Antigen presentation by tumor-associated macrophages drives tumor-infiltrating T cells from a progenitor exhaustion state to terminal exhaustion | |
| diplo-locus：一个轻量级的工具包，用于在一般二倍体选择下进行时间序列遗传数据的推断和模拟 | Cheng, X. | N/A | diplo-locus: A lightweight toolkit for inference and simulation of time-series genetic data under general diploid selection | |
| 映射人类特异性缺失的顺式和反式调控靶基因 | Fair, T. | N/A | Mapping cis- and trans-regulatory target genes of human-specific deletions | |
| 不同扰动下转录变异性的遗传基础 | Tsuru, S. | N/A | Genetic properties underlying transcriptional variability across different perturbations | |
| 雄性小鼠对口腔内辣椒素引发的先天喜好和厌恶反应 | Han, Y. | N/A | Innate liking and disgust reactions elicited by intraoral capsaicin in male mice | |
| 雌二醇的细胞内滞留由乳腺癌细胞中的含GRAM结构域蛋白ASTER-B介导 | Kim, H. B. | N/A | Intracellular Retention of Estradiol is Mediated by GRAM Domain Containing Protein ASTER-B in Breast Cancer Cells | |
| 全国范围内的鸟类生物多样性和迁徙声学监测 | Bick, A. | N/A | National-scale acoustic monitoring of avian biodiversity and migration | |
| 生物分子凝聚体在相分离的质量守恒反应-扩散系统的实验与理论之间架起了桥梁。 | Li, C. | N/A | Biomolecular condensates bridge experiment and theory of mass-conserving reaction-diffusion systems in phase separation | |
| 环状RNA与人类胎盘组织老化和死产中的DNA损伤有关 | Arthurs, A. L. | N/A | Circular RNAs correlate with DNA damage in ageing human placental tissue and in stillbirth | |
| 基于人工智能的发现与低温电子显微镜结构阐明的一种KATP通道药物伴侣蛋白 | Elsheikh, A. | N/A | AI-Based Discovery and CryoEM Structural Elucidation of a KATP Channel Pharmacochaperone | |
| 通过HiCapR映射HIV-1 RNA结构、同源二聚体、长程相互作用及持久性域 | Zhang, Y. | N/A | Mapping HIV-1 RNA Structure, Homodimers, Long-Range Interactions and persistent domains by HiCapR | |
| 神经肌肉骨骼建模揭示了感觉运动皮层中适应性学习的肌肉水平神经动力学 | DeWolf, T. | N/A | Neuro-musculoskeletal modeling reveals muscle-level neural dynamics of adaptive learning in sensorimotor cortex | |
| 各向异性拉伸使多细胞水螅聚集体中的肌动纤维自组织产生偏倚 | Bailles, A. | N/A | Anisotropic stretch biases the self-organization of actin fibers in multicellular Hydra aggregates | |
| 共享和独特的终身压力源特征及网络连接性预测青少年的焦虑和抑郁 | Qu, Y. | N/A | Shared and unique lifetime stressor characteristics and network connectivity predict adolescent anxiety and depression | |
| 基于Transformer的生存结果预测方法 | Mellors, T. | N/A | A Transformer-Based Approach to Survival Outcome Prediction | |
| 折叠稀释和稀释液体积对细菌培养中菌落形成单位估计的影响 | Jain, M. | N/A | The impact of fold-dilution and diluent volume on the estimation of colony forming units in a bacterial culture | |
| 刺皮动物中顺式调控元件和染色质组织的深度保守揭示了动物基因组的祖先调控特征 | Magri, M. S. | N/A | Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes | |
| 肿瘤乳酸脱氢酶C（LDHC）在乳腺癌中的免疫调节作用 | Naik, A. | N/A | Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer | |
| 个性化治疗脑膜瘤：肿瘤类器官药物筛选揭示对HDAC1/2i帕比司他的治疗脆弱性 | Jungwirth, G. | N/A | Personalized Medicine for Meningiomas: Drug Screening on Tumor Organoids Exposes Therapeutic Vulnerabilities to HDAC1/2i Panobinostat | |
| DGKα和ζ缺乏导致调节性T细胞功能失调、不稳定及转化为致病性T滤泡辅助细胞，从而触发以IgG1为主的自身免疫反应。 | Li, L. | N/A | DGKα and ζ Deficiency Causes Regulatory T-Cell Dysregulation, Destabilization, and Conversion to Pathogenic T-Follicular Helper Cells to Trigger IgG1-Predominant Autoimmunity | |
| 非洲慈鲷鱼肠道中适应性细胞进化的超多样性 | Fages, A. | N/A | Adaptive cellular evolution in the intestinal tracts of hyperdiverse African cichlid fishes | |
| 性及应激依赖的基底外侧杏仁核至伏隔核皮质酮释放激素/GABA投射的可塑性，该投射介导奖赏行为 | Taniguchi, L. | N/A | Sex-and Stress-Dependent Plasticity of a Corticotropin Releasing Hormone / GABA Projection from the Basolateral Amygdala to Nucleus Accumbens that Mediates Reward Behaviors | |
| 昼夜活动预测亚洲埋葬甲虫Nicrophorus nepalensis的繁殖物候 | Chen, H. | N/A | Circadian Activity Predicts Breeding Phenology in the Asian Burying Beetle Nicrophorus nepalensis | |
| 可卡因和安非他明调节的转录本在外侧隔核中的厌食和焦虑作用 | Shankhatheertha, A. | N/A | Anorectic and anxiogenic actions of cocaine- and amphetamine-regulated transcript in the lateral septum | |
| 连接梯度的个体独特性是由嵌入网络的复杂性和它们的分散性所驱动的。 | Serhan, Y. | N/A | Individual uniqueness of connectivity gradients is driven by the complexity of the embedded networks and their dispersion | |
| 利用钙成像技术对单个神经元对不同任务相关行为状态的选择性进行稳健表征 | Huang, H. | N/A | Robust characterization of selectivity of individual neurons to distinct task-relevant behavioral states using calcium imaging | |
| 一种用于自动化评估神经退行性疾病小鼠模型中区域性脑萎缩的工具 | Moldenhauer, S. | N/A | A tool to automate assessment of regional brain atrophy in mouse models of neurodegenerative disease | |
| 与肌萎缩侧索硬化症（ALS）相关的共伴侣蛋白DNAJC7通过调节HSF1活性，介导了对蛋白质毒性应激的神经保护作用。 | Fleming, A. C. | N/A | The ALS-associated co-chaperone DNAJC7 mediates neuroprotection against proteotoxic stress by modulating HSF1 activity | |
| 在知觉决策任务的学习初期，内部状态便开始显现。 | Cuturela, L. I. | N/A | Internal states emerge early during learning of a perceptual decision-making task | |
| 戒断初期阻断下丘脑泌素受体1可预防可卡因觅药行为的潜伏，并使多巴胺传递恢复正常 | Clark, P. J. | N/A | Hypocretin Receptor 1 Blockade Early in Abstinence Prevents Incubation of Cocaine Seeking and Normalizes Dopamine Transmission | |
| MortX：一个用于小鼠皮质分割和配准的领域泛化基准 | Iqbal, A. | N/A | MortX: A Domain Generalization Benchmark for Mouse Cortex Segmentation and Registration | |
| 改造Barnes迷宫用于STARR FIELD痴呆小鼠模型：一个为期4天的实验方案，探究学习速率、记忆保持和认知灵活性。 | Bertolli, A. | N/A | Renovating the Barnes maze for mouse models of Dementia with STARR FIELD: A 4-day protocol that probes learning rate, retention and cognitive flexibility. | |
| 基因移动元件在体内介导细胞类型特异的基因组组织和径向基因移动 | Lucas, T. | N/A | Gene mobility elements mediate cell type specific genome organization and radial gene movement in vivo | |
| 小鼠和大鼠尾部附器发育过程中Edar和Xedar的差异表达 | Wisniewski, S. A. | N/A | Differential Expression of Edar and Xedar During Mouse and Rat Tail Appendage Development | |
| 时间不确定性对标志追踪行为的影响 | Kaneko, R. | N/A | Impact of Temporal Uncertainty on Sign-tracking Behavior | |
| 反社会盲穴鱼（Astyanax mexicanus）社会行为的机制 | Sekulovski, B. | N/A | Mechanisms of Social Behavior in the Anti-Social Blind Cavefish (Astyanax mexicanus) | |
| 优化镍钛诺导管的超短脉冲激光制备策略以用于血管介入手术 | Song, Y. | N/A | Optimizing femtosecond laser fabricating strategy of Nitinol hypotube for vascular interventional surgery | |
| 大肠杆菌可溶性polyA聚合酶生产条件的优化 | Oscorbin, I. P. | N/A | Optimization of conditions for production of soluble E. coli polyA-polymerase | |
| ZBP1与ADAR Z-Alpha结构域的染色质相互作用图谱：基于ChIP-Seq的比较研究 | Hamrick, D. | N/A | Mapping Chromatin Interactions of ZBP1 and ADAR Z-Alpha Domains: A ChIP-Seq Based Comparison | |
| 鉴定感染印度奶牛泰勒虫属中与布帕伐醌抗性相关的基因变异。 | Musale, P. | N/A | Identification of genetic variation in genes linked to buparvaquone resistance in Theileria sp infecting dairy cattle in India. | |
| 使用片段连接排他性甲基化测序（FLEXseq）富集低输入和片段化DNA的甲基化组 | Yu, J. | N/A | Enriched Methylomes of Low-input and Fragmented DNA Using Fragment Ligation EXclusive Methylation Sequencing (FLEXseq) | |
| 在真核生物蛋白质组中发现多种嵌合肽，为镶嵌翻译假说的实验验证奠定了基础 | Cakir, U. | N/A | Discovery of diverse chimeric peptides in a eukaryotic proteome sets the stage for the experimental proof of the mosaic translation hypothesis | |
| 使用分子动力学模拟对修饰寡核苷酸进行热力学参数估计 | Park, S. W. | N/A | Thermodynamic Parameter Estimation for Modified Oligonucleotides Using Molecular Dynamics Simulations | |
| 影响复合物I功能的mtDNA点突变m.10191T>C的发病机制是一个多因素过程，导致线粒体代谢重塑。 | Ahmadi, Z. A. | N/A | Pathogenesis of mtDNA point mutation m.10191T>C affecting complex I function is a multifactorial process leading to metabolic remodeling of mitochondria | |
| G-四链体拓扑结构决定了富含鸟嘌呤的生物活性寡核苷酸的功能结果 | Kharel, P. | N/A | G-quadruplex topologies determine the functional outcome of guanine-rich bioactive oligonucleotides | |
| 新型2-花生四烯酰甘油类似物诱导的两步细胞死亡及其在人乳腺癌细胞中受溶血磷脂酰肌醇调节的作用 | Akimov, M. G. | N/A | The Two-Step Cell Death Induction by the New 2-Arachidonoyl Glycerol Analog and its Modulation by Lysophosphatidylino-sitol in Human Breast Cancer Cells | |
| 烟草中环肽的出现与消失揭示了植物代谢演化的动态与机制 | Suh, E. M. | N/A | The emergence and loss of cyclic peptides in Nicotiana illuminate dynamics and mechanisms of plant metabolic evolution | |
| 通过无监督随机森林实现蛋白质构象表示的无偏学习 | Sahil, M. | N/A | Unbiased learning of protein conformational representation via unsupervised random forest | |
| 通过靶向神经氨酸酶活性位点，人类抗体广泛保护流感病毒的结构基础：CDR H3中重复模体的应用 | Jo, G. | N/A | Structural basis of broad protection against influenza virus by a human antibody targeting the neuraminidase active site via a recurring motif in CDR H3 | |
| 节俭的B细胞受体体细胞超突变广义模型 | Sung, K. | N/A | Thrifty wide-context models of B cell receptor somatic hypermutation | |
| 有机和无机氮的协同转化促进了土壤微生物的繁殖，并在融雪期间增加了氮的保留。 | Sorensen, P. | N/A | Coordinated organic and inorganic nitrogen transformations fuel soil microbial blooms and increase nitrogen retention during snowmelt | |
| CpoS四聚体的形成促进了沙眼衣原体感染期间Inc-Inc相互作用。 | Tijerina, X. | N/A | Tetramer formation of CpoS facilitates Inc-Inc interactions during Chlamydia trachomatis infection | |
| 评估oxathiapiprolin作为治疗贝壳杉枯死病潜在药物的植物内效力 | Robinson, H. F. | N/A | Assessing the in planta efficacy of oxathiapiprolin as a potential treatment for kauri dieback disease | |
| miRNAs在调节Nrf1和Nrf2在肝细胞癌上皮-间质转化中不同作用的关键机制 | Chen, J. | N/A | The mechanisms by which miRNAs critically contribute to differential roles of Nrf1 and Nrf2 in modulating the epithelial-mesenchymal transformation of hepatocellular carcinoma | |
| NuMA机械性地独立于其伙伴动力蛋白（dynein）强化纺锤体。 | Cho, N. H. | N/A | NuMA mechanically reinforces the spindle independently of its partner dynein | |
| 高质量的中国白松露基因组和新颖的基于化石校准的盘菌纲分歧估计揭示了真松露基因组进化的速度和模式 | Martelossi, J. | N/A | The high quality Chinese white truffle genome and novel fossil-calibrated estimate of Pezizomycetes divergence reveal the tempo and mode of true truffles genome evolution | |
| CRISPRa介导的与遗传性视网膜营养不良相关的基因在急性分离的人类细胞中的激活，用于诊断目的 | Weber, V. J. | N/A | CRISPRa-mediated activation of genes associated with inherited retinal dystrophies in acutely isolated human cells for diagnostic purposes | |
| TEAL-seq：目标表达分析测序 | Doing, G. | N/A | TEAL-seq: Targeted Expression Analysis Sequencing | |
| 利用深度神经网络全面枚举癌症干细胞样细胞的异质性 | Chowdhury, D. | N/A | Comprehensive Enumeration of Cancer Stem-like Cell Heterogeneity Using Deep Neural Network | |
| 来自毛里求斯食蟹猕猴的多条全长纯合IGH单体型 | Olubo, S. | N/A | Multiple full-length homozygous IGH haplotypes from Mauritian cynomolgus macaques | |
| MultiPopPred：一种跨种族疾病风险预测方法，及其在南亚人群中的应用 | Kamal, R. | N/A | MultiPopPred: A Trans-Ethnic Disease Risk Prediction Method, and its Application to the South Asian Population | |
| 长读长宏基因组样本中微生物污染读段的鉴定与缓解 | Ayala Montano, S. | N/A | Identification and Mitigation of microbial contaminant reads from long-read metagenomic samples | |
| 通过重建亲代和子代链信息来纠正用于稀有等位基因检测的PCR衍生文库中的错误 | Lim, H. | N/A | Correcting errors in PCR-derived libraries for rare allele detection by reconstructing parental and daughter strand information | |
| HyperMPNN - 一种从嗜热菌中学习到的设计耐热蛋白质的通用策略 | Ertelt, M. | N/A | HyperMPNN - A general strategy to design thermostable proteins learned from hyperthermophiles | |
| 利用基因组数据进行多类型种群轨迹的贝叶斯系统发育动力学推断 | Vaughan, T. G. | N/A | Bayesian phylodynamic inference of multi-type population trajectories using genomic dat | |
| 靶向FAK和MEK的药物组合克服了胶质母细胞瘤的肿瘤异质性 | Furqan, M. | N/A | Drug combinations targeting FAK and MEK overcomes tumour heterogeneity in glioblastoma | |
| LNS8801：一种适合临床开发的G蛋白偶联雌激素受体的对映体纯激动剂 | Natale, C. A. | N/A | LNS8801: An enantiomerically pure agonist of the G protein-coupled estrogen receptor suitable for clinical development | |
| MUC5B启动子变异导致非纤维化肺中的蛋白质组变化 | HERRERA, J. A. | N/A | The MUC5B promoter variant results in proteomic changes in the non-fibrotic lung | |
| 实施梭菌属鲁氏菌基因组规模模型以提升合成气发酵 | Scott, W. T. | N/A | Implementation of a Clostridium luticellarii genome-scale model for upgrading syngas fermentations | |
| # BioRxiv 2024-11-30 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 影响单基因树年代测定准确性和精确性的因素 | Louvel, G. | N/A | Factors influencing the accuracy and precision in dating single gene trees | |
| 解码LIPA风险位点与冠心病功能关系的变异体 | Li, F. | N/A | Decoding the Variant-to-Function Relationship for LIPA, a Risk Locus for CAD | |
| 循环免疫细胞中的一种基因表达模块与免疫疾病期间的细胞迁移相关。 | Sinha, D. | N/A | A gene-expression module in circulating immune cells is associated with cell migration during immune diseases. | |
| 学习塑造了前额叶皮层的神经几何结构 | Wojcik, M. J. | N/A | Learning shapes neural geometry in the prefrontal cortex | |
| 解码人脑中观察到的行为背后的物理原理 | Wurm, M. F. | N/A | Decoding the physics of observed actions in the human brain | |
| 健康微生物群——迈向功能性解读 | Zielinska, K. | N/A | Healthy microbiome - moving towards functional interpretation | |
| 人类呼吸道中粘液纤毛清除的结构-功能关系 | Roth, D. | N/A | Structure-function relationships of mucociliary clearance in the human airways | |
| 胰岛素淀粉样形态编码于氢键和静电相互作用，这些相互作用调控蛋白质相分离 | Lenton, S. J. | N/A | Insulin Amyloid Morphology is Encoded in H-bonds and Electrostatics Interactions Ruling Protein Phase Separation | |
| 选择性上皮表达KRASG12D在Oncopig胰腺中驱动导管增生和纤维化 | Jara, C. P. | N/A | Selective epithelial expression of KRASG12D drives ductal proliferation and desmoplasia in the Oncopig pancreas | |
| vmTracking：虚拟标记克服多动物姿态追踪中的遮挡和拥挤问题 | Azechi, H. | N/A | vmTracking: Virtual Markers Overcome Occlusion and Crowding in Multi-Animal Pose Tracking | |
| 对话中的情感内容和语义结构与前额叶皮层的人际神经同步性相关 | Carollo, A. | N/A | Emotional Content and Semantic Structure of Dialogues Are Associated With Interpersonal Neural Synchrony in the Prefrontal Cortex | |
| 蛛形纲大脑的海洋起源揭示了螯肢亚门早期分化 | Strausfeld, N. J. | N/A | Marine Origin of the Arachnid Brain Reveals Early Divergence of Chelicerata | |
| 预测病毒进化的概念和方法 | Meijers, M. | N/A | Concepts and methods for predicting viral evolution | |
| Srs2与PCNA的结合及其SUMO化作用在DNA损伤应答过程中有助于RPA的拮抗作用。 | Fan, J. | N/A | Srs2 binding to PCNA and its sumoylation contribute to RPA antagonism during the DNA damage response | |
| 启用微观现实大脑的电场模型 | Qi, Z. | N/A | Enabling Electric Field Model of Microscopically Realistic Brain | |
| 线粒体钙信号调控纤维层状癌中的支链氨基酸分解代谢 | Marsh, N. M. | N/A | Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma | |
| 对白海扇（Eunicella singularis）毒液的蛋白质组和转录组特征的分析揭示了八放珊瑚类武器库的进化。 | Modica, M. V. | N/A | The proteotranscriptomic characterization of venom in the white seafan Eunicella singularis elucidates the evolution of Octocorallia arsenal | |
| 房室结折返性心动过速在兔房室结模型中的发作、维持及自发性终止，受自主神经系统调控。 | Ryzhii, M. | N/A | Atrioventricular nodal reentrant tachycardia onset,sustainability, and spontaneous termination in rabbit atrioventricular node model with autonomic nervous system control | |
| 传粉者对当地和景观草原特征的反应存在差异 | Lichtenberg, E. M. | N/A | Pollinators differentially respond to local and landscape grassland features | |
| 在调节黑腹果蝇产卵决策中亲属关系和熟悉度相关社会信息的使用 | Rakosy, E. | N/A | On the use of kinship and familiarity associated social information in mediating Drosophila melanogaster oviposition decisions | |
| 解耦冠状病毒Nsp1的功能角色 | Baeumlin, E. | N/A | Uncoupling the functional roles of Coronavirus Nsp1 | |
| 具有社会性抗生素抗性的细菌菌落的空间种群动态 | Denk-Lobnig, M. K. | N/A | Spatial population dynamics of bacterial colonies with social antibiotic resistance | |
| 噬菌体介导的细菌群落间CRISPRi用于生物计算 | Pujar, A. | N/A | Phage-mediated intercellular CRISPRi for biocomputation in bacterial consortia | |
| 使用饱和报告转座子突变技术进行全基因组范围内新基因的鉴定 | Goodall, E. C. A. | N/A | Genome scale identification of new genes using saturated reporter transposon mutagenesis | |
| 伊塔克霉素生物合成需要两种脱氧核糖核酸酶来实现毒素自我抗性。 | Dorival, J. | N/A | Yatakemycin biosynthesis requires two deoxyribonucleases for toxin self-resistance | |
| 具有触发阀的开敞式水渠系统中的毛细流动动力学 | Tokihiro, J. C. | N/A | The dynamics of capillary flow in an open-channel system featuring trigger valves | |
| 溶剂动力学与蛋白质动力学的耦合有助于驱动表皮生长因子受体（EGFR/ErbB1/HER1）激酶域中外显子19缺失突变体的功能差异 | Patil, K. | N/A | Coupled Solvent Dynamics and Protein Dynamics Help Drive Functional Differences in Exon-19 Deletion Mutants in the Epidermal Growth Factor Receptor (EGFR/ErbB1/HER1) Kinase Domain | |
| 铜绿假单胞菌中由RNase E支架结构域介导的关键功能和重要相互作用 | Geslain, S. A. M. | N/A | Critical functions and key interactions mediated by the RNase E scaffolding domain in Pseudomonas aeruginosa | |
| 视觉对象优化头部方向编码 | Siegenthaler, D. | N/A | Visual objects refine head direction coding | |
| 通过花粉间接从头再生法在药用型大麻（Cannabis sativa L.）中实现双单倍体发育。 | Tonolo, F. | N/A | Double haploid development in drug-type Cannabis sativa L. through microspore indirect de-novo plant regeneration. | |
| 土壤真菌间细胞通讯多重筛选的合成平台 | Schiesaro, G. | N/A | A synthetic platform for multiplex screening of cell-cell communication between soil fungi | |
| 使用动态聚焦通道数量可变的组合通道停用策略的成人耳蜗植入者的噪音中言语表现 | Wohlbauer, D. M. | N/A | Speech in noise performance in adults with cochlear implants using a combined channel deactivation strategy with a variable number of dynamic focused channels | |
| 皮层生长抑素中间神经元对神经血管耦合的双向调控 | Mohamed, B. | N/A | Bidirectional control of neurovascular coupling by cortical somatostatin interneurons | |
| 抗噬菌体防御中的淀粉样信号 | Ibarlosa, L. | N/A | Amyloid signaling in antiphage defense | |
| 星形胶质细胞C3产物对tauopathy小鼠模型中神经元线粒体功能障碍的影响 | Lei, C. | N/A | Impact of astrocytic C3-production on neuronal mitochondrial dysfunction in tauopathy mouse models | |
| 综合宏基因组学和血液生物标志物分析揭示了有氧和无氧干预在运动员和非运动员中引起的不同代谢反应 | Zielinska, K. | N/A | Integrative Metagenomic and Blood Biomarker Analysis Reveals Distinct Metabolic Responses to Aerobic and Anaerobic Interventions in Athletic and Non-Athletic Individuals | |
| 不可通行边界生境中的家域溢出：原因、偏差及使用自相关核密度估计的校正 | Hollins, J. P. W. | N/A | Home range spillover in habitats with impassable boundaries: Causes, biases, and corrections using autocorrelated kernel density estimation | |
| 使用BERT分词器建模引物-模板相互作用以预测PCR扩增的注意力-BiLSTM模型 | Latifian, N. | N/A | Modeling Primer-Template Interactions using BERT Tokenizer to Predict PCR Amplification with Attention-BiLSTM | |
| 植物易感性的组织依赖性：通过根部和叶部对系统性植物病原菌拉氏假单胞菌（Ralstonia pseudosolanacearum）在茄子和番茄幼苗中的致病性比较研究 | Bhuyan, S. | N/A | Tissue-dependent nature of plant susceptibility: a comparative pathogenicity study of the systemic phytopathogen Ralstonia pseudosolanacearum in eggplant and tomato seedlings through root and leaf | |
| 瞳孔大小变化揭示认知算术中的贝叶斯推理 | Zenon, A. | N/A | Pupil size variations reveal Bayesian inference in cognitive arithmetic | |
| 对一个由宏基因组组装而成的基因组进行比较基因组分析，揭示了一种毛霉菌目（Mucoromycotina）细根内生菌根真菌中独特的共生特征 | Cole, J. | N/A | Comparative genomic analysis of a metagenome-assembled genome reveals distinctive symbiotic traits in a Mucoromycotina fine root endophyte arbuscular mycorrhizal fungus | |
| 使用一种新方法ARGO（红绿偏移分析），在体内可视化突触小泡蛋白突触蛋白/SNG-1的周转情况 | Shiliaev, N. | N/A | Visualizing turnover of synaptic vesicle protein Synaptogyrin/SNG-1 in vivo using a new method, ARGO (Analysis of Red Green Offset) | |
| 与流量相关的叶片和根系性状的协调影响森林群落构建 | Ma, Z. | N/A | Coordination of flux-related leaf and root traits impacts forest community assembly | |
| 揭示单一人皮肤部位共生棒状杆菌的多样性 | Herman, R. | N/A | Revealing the diversity of commensal corynebacteria from a single human skin site | |
| 基准化浓度和直接提取方法用于废水监测八种人类呼吸道病毒：对快速应用于新型病原体的启示 | Wang, A. L. | N/A | Benchmarking concentration and direct extraction methods for wastewater-based surveillance of eight human respiratory viruses: implications for rapid application to novel pathogens | |
| 伽马同步介导了图形-背景感知 | Karimian, M. | N/A | Gamma Synchrony Mediates Figure-Ground Perception | |
| 不同的参考基因组会影响人口历史重建、选择扫描和群体遗传学总结统计的准确性。 | Akopyan, M. | N/A | Divergent reference genomes compromise the reconstruction of demographic histories, selection scans, and population genetic summary statistics | |
| 谱系对特征的比较分析。 | Anderson, S. A. S. | N/A | The comparative analysis of lineage-pair traits. | |
| 多种途径实现红色类胡萝卜素着色：家朱雀（Haemorhous mexicanus）不使用CYP2J19来产生红色羽毛 | Koch, R. E. | N/A | Multiple pathways to red carotenoid coloration: House finches(Haemorhous mexicanus) do not use CYP2J19 to produce red plumage | |
| 趋同机制，策略各异：广食性与专食性蝙蝠物种花蜜摄入方式的比较 | Quinche, L. L. | N/A | Convergent mechanisms, divergent strategies: a comparison of nectar intake between a generalist and a specialized bat species | |
| 高级人脑类器官作为研究胶质瘤干细胞与小胶质细胞及血管细胞相互作用及对放疗反应的模型 | Raguin, J. | N/A | Advanced human cerebral organoids as a model for investigating glioma stem cell interactions with microglia and vascular cells and response to radiotherapy | |
| 腹侧嘴侧延髓（RVM）投射到外侧下丘脑区域（LHA），以驱动厌恶和焦虑。 | Rani, M. | N/A | Rostral ventromedial medulla (RVM) projects to the lateral hypothalamic area (LHA) to drive aversion and anxiety | |
| 急性束缚应激和疼痛调节依赖于中脑导水管周围灰质与外侧隔核之间的相互作用。 | Shah, D. P. | N/A | Acute restraint stress and pain modulation depend on the interaction between the periaqueductal gray and the lateral septum | |
| 增强的大脑-心脏连接作为治疗性虚拟现实沉浸后状态焦虑减少的前兆 | Sezer, I. | N/A | Enhanced Brain-Heart Connectivity as a Precursor of Reduced State Anxiety After Therapeutic Virtual Reality Immersion | |
| 在非洲参与野味供应链的哺乳动物中检测到多种病毒 | Geraerts, M. | N/A | A wide diversity of viruses detected in African mammals involved in the wild meat supply chain | |
| NaDyNet：一个用于自然刺激动态网络分析的工具箱 | Yang, J. | N/A | NaDyNet: A Toolbox for Dynamic Network Analysis of Naturalistic Stimuli | |
| 描述人类海马-皮层网络中电刺激引起的神经元和群体反应 | van der Plas, M. | N/A | Characterizing neuronal and population responses to electrical stimulation in the human hippocampo-cortical network | |
| CA2神经元在盐皮质激素受体敲除中的命运（或状态）。 | Harris, E. P. | N/A | Fate (or state) of CA2 neurons in a mineralocorticoid receptor knockout. | |
| 4-甲基伞形酮（4-MU）通过改善学习和记忆障碍，对脑缺血/再灌注损伤具有神经保护作用。 | Tamouk, S. | N/A | 4-Methyllumbiferone (4-MU) exerts a neuroprotective effect against cerebral ischemia/reperfusion injury by ameliorating learning and memory impairments | |
| 体内网络活动的调节驱动了轴突始段处轴-轴突突触的纳米级重组织 | Compans, B. | N/A | In vivo modulation of network activity drives the nanoscale reorganisation of axo-axonic synapses at the axon initial segment | |
| 剖析C端截短在调节aSyn病理形成和Lewy小体生物发生中的不同作用 | Mahul-Mellier, A.-L. | N/A | Dissecting the differential role of C-terminal truncations in the regulation of aSyn pathology formation and the biogenesis of Lewy bodies | |
| 宜人的香气：通往舒缓自主反应和改善脑-体节律耦合的特权之门 | Ghibaudo, V. | N/A | Pleasant smells: a privileged gateway to soothing autonomic responses and improving brain-body rhythm coupling | |
| 非平衡动力学作为微扰复杂性的起源 | Stikvoort, W. | N/A | Nonequilibrium dynamics elicited as the origin of perturbative complexity | |
| 肠道菌群失调改变了急性癫痫负担及抗癫痫药物在Theiler病毒性脑炎模型中的活性 | Erickson, I. | N/A | Intestinal Dysbiosis Alters Acute Seizure Burden and Antiseizure Medicine Activity in the Theiler's Virus Model of Encephalitis | |
| 在帕金森病中，从稳定位置开始迈步时，下肢的快速视觉运动反应得以保留。 | Billen, L. S. | N/A | Lower-limb express visuomotor responses are spared in Parkinson's Disease during step initiation from a stable position | |
| 一种广谱锈菌中假定的效应因子基因组内变异推动了早期感染阶段 | Degnan, R. | N/A | Intragenomic variants of a putative effector drive early-stage infection in a broad host-range rust fungus | |
| 心外膜分泌组特征及其功能评估：源自心外膜的细胞外囊泡与基质 | Oliveira, C. C. | N/A | Characterization and Functional Assessment of Epicardial Secretome: Epicardium-Derived Extracellular Vesicles and Matrix | |
| 整体遗传条形码揭示了组织巨噬细胞发育的谱系树 | Frank, L. | N/A | Holistic genetic barcoding reveals a lineage tree of tissue macrophage development | |
| 微外显子剪接调节因子srrm4的突变对斑马鱼神经发育的表型影响较小 | Gupta, T. | N/A | Mutations in the microexon splicing regulator srrm4 have minor phenotypic effects on zebrafish neural development | |
| 评估气质对圈养红小鹿（Mazama americana）训练效率的影响 | Gragnanello, L. C. | N/A | Assessing the impact of temperament on training efficiency in x-situ Red Brocket Deer (Mazama americana) | |
| 系统阻断多巴胺受体对大鼠双向主动回避获取的影响。 | Vercammen, L. | N/A | The impact of systemic blockade of dopamine receptors on the acquisition of two-way active avoidance in rats. | |
| 恐惧泛化的增加导致消退泛化的减少 | Lopez-Moraga, A. | N/A | Increased fear generalization results in reduced generalization of extinction | |
| 一种光学脑机接口揭示了后顶叶皮层在目标导向导航中的因果作用 | Sorrell, E. | N/A | An optical brain-machine interface reveals a causal role of posterior parietal cortex in goal-directed navigation | |
| 将理想贝叶斯搜索器与神经网络模型结合用于混合搜索任务中的眼动预测 | Ruarte, G. | N/A | Integrating Ideal Bayesian Searcher and Neural Networks Models for Eye Movement Prediction in a Hybrid Search Task | |
| 无需配对高场扫描的儿童超低场MRI深度学习超分辨率 | Briski, U. | N/A | Deep learning super-resolution of paediatric ultra-low-field MRI without paired high-field scans | |
| 计算约束在猕猴V4拓扑图功能域出现中的作用 | Jiang, D. | N/A | Computational constraints underlying theemergence of functional domains in thetopological map of Macaque V4 | |
| 通过RNA干扰同时靶向HIF1A和HIF2A的双重基因疗法减轻了两种AMD小鼠模型中的视网膜退化 | Ebner, L. J. A. | N/A | Dual-acting gene therapy targeting HIF1A and HIF2A by RNA interference mitigates retinal degeneration in two mouse models of AMD | |
| 红色代表沉重：行动意图重新激活与任务相关的认知线索的表征 | Lee, N. | N/A | Red means heavy: Action intentions reactivate representations of task-relevant cognitive cues | |
| 半自动导航用于高效定位电子断层扫描在体积相关光电子显微镜中的感兴趣区域 | Konishi, K. | N/A | Semi-automated navigation for efficient targeting of electron tomography to regions of interest in volume correlative light and electron microscopy | |
| 小鼠上丘投射至下橄榄核神经元的解剖学和功能检查 | David, D. L. | N/A | Anatomical and functional examination of superior colliculus projections to the inferior olivary neurons in mice | |
| 利用一种新型病毒工具探索CA3记忆细胞性质的早期变化 | Cupolillo, D. | N/A | Early changes in the properties of CA3 engram cells explored with a novel viral tool | |
| 推断子采样神经系统中的全局指数 | Conte, D. | N/A | Inferring global exponents in subsampled neural systems | |
| 视觉剥夺与视觉恢复中的灰质异常 | Pedersini, C. A. | N/A | Gray matter abnormalities in sight deprivation and sight restoration | |
| 基于核的LFP估计在详细的大规模脉冲网络模型中的小鼠视觉皮层模型 | Meneghetti, N. | N/A | Kernel-based LFP estimation in detailed large-scale spiking network model of mouse visual cortex | |
| 黑色素细胞和荧光白色素细胞协同作用，为阿拉伯鳉鱼（Aphanius dispar）胚胎提供紫外线光保护。 | Alenize, M. | N/A | Melanophore and fluoroleucophore synergistically photo-protect the Arabian killifish, Aphanius dispar, embryo from ultraviolet light | |
| 低氧抑制蝾螈骨骼肌的去分化 | Vdovin, G. | N/A | Hypoxia inhibits newt skeletal muscle dedifferentiation | |
| 神经证据表明存在与动作相关的体感预测 | Moran, C. | N/A | Neural evidence for action-related somatosensory predictions | |
| 高效整合基因库至酵母胞质质粒 | Pisera, A. | N/A | Ultra-Efficient Integration of Gene Libraries onto Yeast Cytosolic Plasmids | |
| 在人肾类器官中定义和控制轴向肾单位模式与合成Wnt分泌组织者 | Fausto, C. C. | N/A | Defining and Controlling Axial Nephron Patterning in Human Kidney Organoids with Synthetic Wnt-Secreting Organizers | |
| 年龄是疟疾炎症反应的内在驱动因素 | Loughland, J. | N/A | Age is an intrinsic driver of inflammatory responses to malaria | |
| 连接体外与体内洞察：一种针对多药耐药铜绿假单胞菌的有效噬菌体疗法的药代动力学-药效学模型 | Cha, J. S. | N/A | Bridging in vitro and in vivo insights: A PKPD model for effective phage therapy against multidrug-resistant Pseudomonas aeruginosa | |
| 在病毒附着和进入过程中扮演双重角色，使得人巨细胞病毒的gHgLgO三聚体成为病毒感染力的核心因素。 | Thiessen, L. | N/A | A dual role in virion attachment and entry makes the human cytomegalovirus gHgLgO trimer the central player in virion infectivity | |
| 黄病毒NS1引发的血管内皮功能障碍促进病毒扩散 | Puerta-Guardo, H. | N/A | Flavivirus NS1-triggered endothelial dysfunction promotes virus dissemination | |
| 依赖于FAD的单加氧酶在链霉菌ambofaciens中对金霉素重氮基功能化的作用 | Vicente, C. M. | N/A | Role of a FAD-dependent monooxygenase in diazo group functionalisation of kinamycin in Streptomyces ambofaciens | |
| 从拉曼光谱直接识别特征并实现单分生孢子物种水平上的植物病原体精准数据驱动分类 | Xu, X. | N/A | Direct Feature Identification from Raman Spectra and Precise Data-driven Classification of Phytopathogens at Single Conidium-Species Level | |
| 基于OMV的脑膜炎球菌疫苗对N. gonorrhoeae的保护作用与跨物种定向的体液和细胞免疫反应有关。 | Zhu, W. | N/A | Protection against N. gonorrhoeae induced by OMV-based Meningococcal Vaccines are associated with cross-species directed humoral and cellular immune responses | |
| 土壤中活性氧物种与氮循环的动态变化作为挥发性活性氮氧化物产生的机制 | Purchase, M. L. | N/A | Dynamics of Reactive Oxygen Species and Nitrogen Cycling in Soils as a Mechanism for Volatile Reactive Nitrogen Oxide Production | |
| 细菌核糖体生物合成的进化灵活性 | Amikura, K. | N/A | Evolutionary flexibility of ribosome biogenesis in bacteria | |
| 全基因组测绘揭示EB病毒诱导的基因组变异，识别MUC19在EB病毒潜伏期中的作用 | Yu, J. | N/A | Genome-wide mapping of EBV-induced genomic variationsidentifies the role of MUC19 in EBV latency | |
| 人巨细胞病毒全病毒蛋白质组学揭示gpUL141是一种病毒颗粒成分，通过调节包膜糖蛋白组成以抵御体液免疫 | Bentley, K. | N/A | Whole Virion Proteomics of HCMV Reveals that gpUL141 is a Virion Component that Regulates Envelope Glycoprotein Composition to Protect Against Humoral Immunity | |
| 流感病毒A诱导的内质网PI4P生成涉及ATG16L1，并促进病毒核糖核蛋白的释放 | Alemany, C. | N/A | Influenza A virus-induced production of PI4P at the endoplasmic reticulum involves ATG16L1 and promotes the egress of viral ribonucleoproteins | |
| 适应四环素可抑制系统以调节新生隐球菌中必需基因的表达 | Fu, C. | N/A | Adaptation of the tetracycline-repressible system for modulating the expression of essential genes in Cryptococcus neoformans | |
| 失调的RNA剪接导致酒精相关性肝病中的再生失败 | Chembazhi, U. V. | N/A | Dysregulated RNA splicing induces regeneration failure in alcohol-associated liver disease | |
| 完整的信使RNA存在于人体血浆和尿液中，并且它们的纯化大分子隔室中。 | Verwilt, J. | N/A | Intact messenger RNA exists in human blood plasma and urine, and their purified macromolecular compartments | |
| 高灵敏度逆转录环介导等温扩增技术用于检测和鉴定花生环斑病毒和番茄斑萎病毒 | de Breuil, S. | N/A | Highly sensitive reverse transcription loop-mediated isothermal amplification for detecting and identifying groundnut ringspot and tomato spotted wilt orthotospoviruses | |
| O-GlcNAc糖基化下调增强了依托泊苷诱导的HepG2人肝癌细胞中p53介导的凋亡 | Lee, J. | N/A | Downregulation of O-GlcNAcylation enhances etoposide-induced p53-mediated apoptosis in HepG2 human liver cancer cells | |
| 序列组成决定凝聚相的混溶性 | Pei, G. | N/A | Sequence Composition Dictates Condensate Miscibility | |
| 体外通过Sortase A介导的法尼基化Cdc42 | Tschirpke, S. | N/A | Sortase A-mediated farnesylation of Cdc42 in vitro | |
| 通过利什曼原虫墨西哥变种嘌呤2'-脱氧核糖基转移酶活性位点工程实现阿拉伯糖苷核苷的高效合成 | Cecchini, D. A. | N/A | Efficient synthesis of arabinosyl nucleosides via active site engineering of the Leishmania mexicana purine 2'-deoxyribosyltranferase | |
| TTF2促进停滞的复制叉在有丝分裂中被排出 | Can, G. | N/A | TTF2 promotes replisome eviction from stalled forks in mitosis | |
| 对疟原虫肌动蛋白解聚因子与磷脂酰肌醇相互作用的功能性见解 | Lasiwa, D. | N/A | Functional insights into Plasmodium actin depolymerizing factor interactions with phosphoinositides | |
| MnmE-MnmG复合物的冷冻电镜结构揭示了其巨大的构象变化，并为tRNA修饰机制提供了新的见解。 | Maes, L. | N/A | Cryo-EM structures of the MnmE-MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification | |
| 计算机辅助设计的Z域肽，具有增强的VEGF抑制作用 | Geist, C. | N/A | Computer-guided design of Z domain peptides with improved inhibition of VEGF | |
| RBR E3泛素连接酶HOIL-1能够在体外泛素化多种非蛋白质底物。 | Wang, X. | N/A | The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-proteinaceous substrates in vitro | |
| # BioRxiv 2024-11-29 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 撤回：利用物理信息元神经表示实现生物动力学的高保真、可泛化光场重构 | Yi, C. | N/A | WITHDRAWN: High-fidelity, generalizable light-field reconstruction of biological dynamics with physics-informed meta neural representation | |
| 芯片感染：一种用于研究脑膜炎奈瑟菌定植和血管损伤的体外人血管模型 | Pinon, L. | N/A | Infection-on-Chip: an in vitro human vessel to study Neisseria meningitidis colonization and vascular damages | |
| mbctools: 一个用户友好的宏条形码分析和跨平台管道，用于分析大量生物多样性中的多种扩增子测序数据 | Barnabe, C. | N/A | mbctools: A User-Friendly Metabarcoding and Cross-Platform Pipeline for Analyzing Multiple Amplicon Sequencing Data across a Large Diversity of Organisms | |
| 挑战反向传播：皮质中目标学习的证据 | Aceituno, P. V. | N/A | Challenging Backpropagation: Evidence for Target Learning in the Cortex | |
| 急性心理社会压力诱导的能量应激标志物GDF15 | Huang, Q. | N/A | The Energetic Stress Marker GDF15 is Induced by Acute Psychosocial Stress | |
| 灵活的海马体对抽象边界的表征支持记忆引导的选择。 | Esposito, M. | N/A | Flexible hippocampal representation of abstract boundaries supports memory-guided choice. | |
| 一项系统综述量化了负责病原体传播的库蠓属物种的宿主吸食模式 | Fairbanks, E. L. | N/A | A systematic review quantifying host feeding patterns of Culicoides species responsible for pathogen transmission | |
| 子宫肌瘤和宫颈癌中DEK表达的上调作为潜在的预后因素 | Janiak, A. | N/A | Upregulation of DEK Expression in Uterine Myomas and Cervical Cancer as a Potential Prognostic Factor | |
| 探索SNP过滤策略：严格核心与软核心的影响 | Taouk, M. L. | N/A | Exploring SNP Filtering Strategies: The Influence of Strict vs Soft Core | |
| 多聚磷酸盐比DNA更有效地区分蛋白质构象系综，促进多样化的组装和成熟行为。 | Goyal, S. | N/A | Polyphosphate Discriminates Protein Conformational Ensembles More Efficiently than DNA Promoting Diverse Assembly and Maturation Behaviors | |
| 撤回：miRBench：一个全面的微RNA结合位点预测训练和基准测试数据集 | Sammut, S. | N/A | WITHDRAWN: miRBench: A Comprehensive microRNA Binding Site Prediction Training and Benchmarking Dataset | |
| 人工智能建模能否区分传感器和辅助NLR免疫受体之间的蛋白质结构差异？ | Toghani, A. | N/A | Can AI modelling of protein structures distinguish between sensor and helper NLR immune receptors? | |
| 从辣木（Moringa oleifera）种子中提取的纯化几丁质结合蛋白对小鼠伊立替康诱导的肠道黏膜炎的治疗效果 | Ferreira, K. Q. | N/A | Therapeutic effects of a purified chitin-binding protein from Moringa oleifera seeds on irinotecan-induced intestinal mucositis in mice | |
| 帕金森病影响快速视觉运动反应的上下文控制，但不影响其表达，该反应启动视觉引导的伸手动作：多重交互运动通路的证据及其对帕金森病运动症状的启示 | Gilchrist, M. | N/A | Parkinson's Disease affects the contextual control, but not the expression, of a rapid visuomotor response that initiates visually-guided reaching: Evidence for multiple, interacting motor pathways and implications for motor symptoms in Parkinson's Disease | |
| 静息状态下的阿尔法反应性在帕金森病中降低，并与步态变异性相关。 | Lirani-Silva, E. | N/A | Resting-state alpha reactivity is reduced in Parkinson disease and associated with gait variability | |
| 在自然音乐聆听过程中人类听觉皮层的多流预测 | Robert, P. | N/A | Multi-stream predictions in human auditory cortex during natural music listening | |
| 利用深度学习从大脑结构预测内化问题 | Vandewouw, M. M. | N/A | Using deep learning to predict internalizing problems from brain structure | |
| 失眠症患者静息态功能磁共振成像研究揭示脑动力学模型显示脑状态切换减少 | Jespersen, K. V. | N/A | Modelling of brain dynamics reveals reduced switching between brain states in insomnia disorder - a resting state fMRI study | |
| 未知来源的自发性炎症的成年患者在免疫表现上部分类似于斯蒂尔病。 | Veiga, R. | N/A | Adults patients with autoinflammation of unknown origin partially phenocopy the immune presentation of Still's disease | |
| 对伊拉克患者中鲍氏不动杆菌和索布雷菌医院感染的碳青霉烯酶编码基因的调查 | Al-Ouqaili, M. T. S. | N/A | An investigation of carbapenemase-encoding genes in Burkholderia cepacia and Aeromonas sobria nosocomial infections among Iraqi patients | |
| 拮抗细菌对不同军团菌种的抑制作用存在差异 | Cavallaro, A. | N/A | Variable inhibition of different Legionella species by antagonistic bacteria | |
| 大型建筑物饮用水系统中军团菌肺炎菌株的基因组分析，历时25年 | Seth-Smith, H. M. | N/A | Genomic Analysis of Legionella pneumophila in the Drinking Water System of a Large Building over 25 Years | |
| MuMu：一种用于基于液滴的同时单细胞核RNA测序和ATAC测序系统的样本多路复用协议 | Li, Z. | N/A | MuMu: a sample multiplexing protocol for droplet-based simultaneous single nuclei RNA- and ATAC-seq systems | |
| 在预先使用硫芥子素结合物处理的树突状细胞中抑制NF-kappaB可诱导免疫耐受 | Palomares, F. | N/A | NF-kappaB inhibition in dendritic cells pre-treated with sulforaphane-conjugates induces immunotolerance | |
| 针对白纹伊蚊的不相容昆虫技术的发展：引入野生核背景恢复了人工感染沃尔巴克氏菌雄蚊的表现 | Lejarre, Q. | N/A | Development of the Incompatible Insect Technique targeting Aedes albopictus: introgression of a wild nuclear background restores the performance of males artificially infected with Wolbachia | |
| 液泡pH通过TORC1信号传导在酵母复制衰老过程中调节网格蛋白介导的内吞作用 | Antenor, K. G. | N/A | Vacuolar pH regulates clathrin-mediated endocytosis through TORC1 signaling during yeast replicative aging | |
| 成熟的簇细胞表型沿着肠道隐窝-绒毛轴在细胞因子诱导的簇细胞增生后依次表达。 | des Amorie, J. R. B. | N/A | Mature tuft cell phenotypes are sequentially expressed along the intestinal crypt-villus axis following cytokine-induced tuft cell hyperplasia | |
| 突触线粒体的生物能量特征 | Faria-Pereira, A. | N/A | Bioenergetic signature of Synaptic mitochondria | |
| GABRA1移码变异损害GABAA受体蛋白稳态 | Williams, M. P. | N/A | GABRA1 frameshift variants impair GABAA receptor proteostasis | |
| 动脉粥样易损血流激活SMAD-FOXO1驱动内皮间质转化及动脉粥样硬化 | Knaus, P. | N/A | Atheroprone Flow Activates SMAD-FOXO1 to drive Endothelial-to-Mesenchymal Transition and Atherosclerosis | |
| TFEB/HLH-30介导的成年早期神经元溶酶体容量扩展在衰老过程中保护秀丽隐杆线虫树突的维持 | Zhong, R. | N/A | TFEB/HLH-30-mediated expansion of neuronal lysosomal capacity in early adulthood protects dendrite maintenance during aging in Caenorhabditis elegans | |
| 仿生多孔硅用于合理设计的联合疗法，以诱导免疫原性细胞死亡 | Saarela, S. | N/A | Biomimetic porous silicon for rationally engineered combination therapy to induce immunogenic cell death | |
| 用于空间飞行基因表达谱分析的Perturb-Seq数据机器学习模型 | Johnson, L. F. | N/A | A Machine Learning Model of Perturb-Seq Data for Use in Space Flight Gene Expression Profile Analysis | |
| 从综合AI和聚合物物理模型中得出的染色质结构 | Schultz, E. R. | N/A | Chromatin Structures from Integrated AI and Polymer Physics Model | |
| 电荷筛选和疏水性驱动反射蛋白的逐步组装和液-液相分离 | Gordon, R. | N/A | Charge screening and hydrophobicity drive progressive assembly and liquid-liquid phase separation of reflectin protein | |
| 含有糖脂的多分散寡层囊泡的小角和准弹性中子散射 | Bange, L. | N/A | Small-angle and quasi-elastic neutron scattering from polydisperse oligolamellar vesicles containing glycolipids | |
| 智能三维超分辨率显微镜揭示了核仁中RNA支架的结构 | Berrevoets, E. S. | N/A | Smart 3D super-resolution microscopy reveals the architecture of the RNA scaffold in a nuclear body | |
| 脂质纳米颗粒pH驱动相变的机理洞察 | Trollmann, M. F. | N/A | Mechanistic Insight into pH-Driven Phase Transition of Lipid Nanoparticles | |
| 利用傅里叶叠层散射光显微技术解析脑、关节和肌肉组织的结构复杂性 | van Staalduine, S. E. | N/A | Deciphering Structural Complexity of Brain, Joint, and Muscle Tissues Using Fourier Ptychographic Scattered Light Microscopy | |
| 遗传性痉挛性截瘫相关突变残基的结构和功能作用：从katanin螺旋到环状结构转变模拟中获得的见解 | Kelly, M. S. | N/A | Structural and functional role of residues undergoing hereditary spastic paraplegias-linked mutations: insights from a simulation of the spiral to ring transition in katanin | |
| 对细菌外膜脂质稳态中重要的马达-定子复合物力传导机制的结构洞察 | Yeow, J. | N/A | Structural insights into the force-transducing mechanism of a motor-stator complex important for bacterial outer membrane lipid homeostasis | |
| 解密Cav1中的Ca²⁺渗透与价态选择性：分子动力学模拟揭示三离子撞击机制 | Xue, L. | N/A | Deciphering Ca2+ Permeation and Valence Selectivity in Cav1: Molecular Dynamics Simulations Reveal the Three-Ion Knock-on Mechanism | |
| 对动力蛋白-动力蛋白激活蛋白-NuMA复合物的激活和调控的结构和功能见解 | Aslan, M. | N/A | Structural and functional insights into activation and regulation of the dynein-dynactin-NuMA complex | |
| 具有内在无序区域的转录因子设计原则 | Ji, W. | N/A | Design principles of transcription factors with intrinsically disordered regions | |
| 多组学分析揭示了溶瘤性寨卡病毒感染儿童脑肿瘤细胞所引发的关键免疫原性特征 | Sherwood, M. | N/A | Multiomics analysis reveals key immunogenic signatures induced by oncolytic Zika virus infection of paediatric brain tumour cells | |
| 空间通量平衡分析揭示了肾癌和结直肠癌的组织来源和空间依赖性代谢重编程 | Maspero, D. | N/A | Spatial Flux Balance Analysis reveals tissue-of-origin and spatially dependent metabolic rewiring in renal and colorectal cancer | |
| 来自EIAV疫苗的环境因素通过减弱NLRP3与NEK7的相互作用，精细调控NLRP3的激活。 | Guo, x. | N/A | Env from EIAV vaccine delicately regulates NLRP3 activation via attenuating NLRP3-NEK7 interaction | |
| 在恒河猴中针对HIV包膜糖蛋白的保守融合肽进行免疫聚焦 | Pratap, P. P. | N/A | Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques | |
| 城市化与当地环境异质性对热带蛙类表型变异性的影响 | Provete, D. B. | N/A | The effect of urbanization and local environmental heterogeneity on phenotypic variability in a tropical frog | |
| 全球的山路显著改变了当地土壤的微气候。 | Lejeune, R. | N/A | Mountain roads across the globe significantly alter local soil microclimates | |
| 基因网络拓扑结构驱动基因表达的突变景观 | Le Rouzic, A. | N/A | Gene network topology drives the mutational landscape of gene expression | |
| 人类转录因子在跨组织中的异构体转换提示了一种广泛存在的调控机制。 | Sidorov, S. | N/A | Cross-tissue isoform switches by human transcription factors suggest a widespread regulatory mechanism | |
| 新型沙雷氏菌（Serratia sarumanii）菌株GBS19的农药降解能力及其基因组特征 | Alatassi, G. | N/A | Pesticide degradation capacity of a novel strain belonging to Serratia sarumanii (GBS19) with its genomic profile | |
| 利用纳米孔的马达蛋白辅助糖链转移和测序 | Gao, Z. | N/A | Motor protein-assisted glycan translocation and sequencing using nanopores | |
| 鉴定神经调节蛋白为SERCA2b调节蛋白样蛋白及其通过粗粒度模拟评估其聚集倾向。 | Ben Mariem, O. | N/A | Identification of neuronatin as a SERCA2b regulin-like protein and assessment of its aggregation propensity via coarse grained simulations. | |
| 解码糖基转移酶-B酶中决定底物特异性的因素——来自机器学习模型的见解 | Hennen, S. | N/A | Decoding substrate specificity determining factors in glycosyltransferase-B enzymes - Insights from machine learning models | |
| 利用系统免疫学方法连接免疫型和肠型 | Affaticati, F. | N/A | Bridging immunotypes and enterotypes using a systems immunology approach | |
| 肠道微生物群中细菌丰度的时间波动生态尺度取决于个体微生物物种和细菌群落的功能特性 | Su, P. | N/A | Ecological Scaling of Temporal Fluctuations with Bacterial Abundance in Gut Microbiota Depends on Functional Properties of Individual Microbial Species and Bacterial Communities | |
| 对八种人类呼吸道病毒的污水监测：浓度法与直接提取法的基准测试及其对新型病原体快速应用的启示 | Jiang, M. | N/A | Benchmarking concentration and direct extraction methods for wastewater-based surveillance of eight human respiratory viruses: implications for rapid application to novel pathogens | |
| 血浆蛋白酶-哌喹悖论持续存在 | Walsh, B. | N/A | The Plasmepsin-Piperaquine Paradox Persists | |
| 在热应激期间小鼠胚胎干细胞中RNA聚合酶III转录的动态调节 | Nguyen, T. F. | N/A | Dynamic regulation of RNA Polymerase III transcription in mouse embryonic stem cells during heat shock stress | |
| AEGIS：基于个体的生命史进化模型 | Bagic, M. | N/A | AEGIS: individual-based modeling of life history evolution | |
| 通过自然转化在人类肠道微生物组中测量微生物群落范围内的抗生素抗性传播 | Chowdhury, N. N. | N/A | Measuring Microbial Community-Wide Antibiotic Resistance Propagation via Natural Transformation in the Human Gut Microbiome | |
| 使用对称多项逻辑回归增强单核苷酸多态性基因分型 | Nielsen, M. B. | N/A | Enhanced SNP Genotyping with Symmetric Multinomial Logistic Regression | |
| 使用DNBSEQ全基因组测序进行结构变异检测的性能评估 | Rao, J. | N/A | Performance evaluation of structural variation detection using DNBSEQ whole-genome sequencing | |
| 对Lasius蚁属的基因组数据进行去污染，以实现准确的物种划分和杂交检测 | Jecha, K. | N/A | Decontaminating genomic data for accurate species delineation and hybrid detection in the Lasius ant genus | |
| 来自Thermococcus onnurineus的热稳定CAS-Cas4对分支DNA的处理：扩展核酸酶活性的生化景观 | Jain, M. | N/A | Branched DNA Processing by a Thermostable CAS-Cas4 from Thermococcus onnurineus: Expanding Biochemical Landscape of Nuclease Activity | |
| 基于mTurquoise2的葡萄糖生物传感器 | Botman, D. | N/A | An mTurquoise2-based glucose biosensor | |
| 通过超解旋酶介导的等温扩增，实现了对高度重复或低复杂度序列DNA的可靠扩增。 | Kang, J. | N/A | Reliable amplification of highly repetitive or low complexity sequence DNA enabled by superhelicase-mediated isothermal amplification | |
| 从头功能发现来自重组酶构建的大多样性单克隆T细胞库中的肽-MHC限制性CARs | Wang, Z. | N/A | De novo functional discovery of peptide-MHC restricted CARs from recombinase-constructed large-diversity monoclonal T cell libraries | |
| 用于RNA功能和结构预测的大规模基础模型 | Zou, S. | N/A | A Large-Scale Foundation Model for RNA Function and Structure Prediction | |
| 嵌入式极值搜索：一种生物合成优化器 | Smart, B. C. | N/A | Embedded Extremum Seeking: A Bio-synthetic Optimiser | |
| 利用自适应反馈控制工程细胞命运 | Britto Bisso, F. | N/A | Engineering cell fate with adaptive feedback control | |
| 在CD4结合位点映射关键体细胞超突变有助于HIV-1疫苗设计 | Dam, K.-M. A. | N/A | Mapping essential somatic hypermutations in a CD4-binding site bNAb informs HIV-1 vaccine design | |
| Raver1将Ripk1 RNA剪接与caspase-8介导的焦亡细胞死亡、炎症及病原体抵抗联系起来 | Zhang, B. | N/A | Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance | |
| 抗体反应的亲和力成熟是由不同浆细胞增殖介导的。 | MacLean, A. J. | N/A | Affinity maturation of antibody responses is mediated by differential plasma cell proliferation | |
| 从表型到受体：通过全面的受体分析验证大肠杆菌噬菌体的生理聚类 | Kaneko, T. | N/A | From phenotype to receptor: validating physiological clustering of Escherichia coli phages through comprehensive receptor analysis | |
| 鉴定临床碳青霉烯酶、478种新型β-内酰胺酶以及从受污染的高北极峡湾沉积物中推测出的七个新的细菌门类。 | Marathe, N. P. | N/A | Identification of clinical carbapenemases, 478 novel β-lactamases and putative seven new bacterial phyla from wastewater contaminated high arctic fjord sediments. | |
| 利用DeepCellMap这一结合深度学习和空间统计的深度学习方法，解析发育中人脑中微胶质细胞的空间组织结构。 | Perochon, T. | N/A | Unraveling Microglial Spatial Organization in the Developing Human Brain with DeepCellMap, a Deep Learning Approach Coupled to Spatial Statistics | |
| 单细胞RNA测序显示，三刺鱼中没有减数分裂性染色体失活的现象。 | Shaw, D. | N/A | Single cell RNA-sequencing reveals no evidence for meiotic sex chromosome inactivation in the threespine stickleback fish | |
| 一种药物分子伴侣稳定剂能够挽救G蛋白偶联受体中绝大多数致病变异体的表达。 | Mighell, T. | N/A | A pharmacological chaperone stabilizer rescues the expression of the vast majority of pathogenic variants in a G protein-coupled receptor | |
| 增强多基因适应性检测：基于模拟进化与重测序数据的机器学习与统计方法比较研究 | Caliendo, C. | N/A | Enhancing Detection of Polygenic Adaptation: A Comparative Study of Machine Learning and Statistical Approaches Using Simulated Evolve-and-Resequence Data | |
| 寄生蜂Nasonia vitripennis的发育性DNA甲基化 | Thomas, C. L. | N/A | Developmental DNA Methylation in the Parasitoid Wasp Nasonia vitripennis | |
| 用于肺炎链球菌监测的可移植可扩展基因组分析流程：GPS流程 | Hung, H. C. H. | N/A | A Portable and Scalable Genomic Analysis Pipeline for Streptococcus pneumoniae Surveillance: GPS Pipeline | |
| CCA相关细菌对抗抗生素耐药性病原体的潜力：一项基因组调查 | Lera-Lozano, D. | N/A | The Potential of CCA-associated Bacteria to Fight Antimicrobial-Resistant Pathogens: a Genomic Survey | |
| 抗原-葡聚糖聚合物的开发用于检测和评估CAR T细胞 | Friis, R. | N/A | Development of antigen-dextramers for detection and evaluation of CAR T cells | |
| 药物抗性心脏重编程可缓解多柔比星诱导的小鼠和猪的心脏毒性 | Zhang, Y. | N/A | Cardiac Reprogramming with Drug Resistance Alleviates Doxorubicin-induced Cardiotoxicity in Mice and Pigs | |
| # BioRxiv 2024-11-28 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 从局部相互作用和光滑梯度中涌现出强大的全局模块 | Khona, M. | N/A | Emergence of robust global modules from local interactions and smooth gradients | |
| KPop：通过序列嵌入实现微生物基因组的准确且可扩展的比较分析 | Didelot, X. | N/A | KPop: Accurate and scalable comparative analysis of microbial genomes by sequence embeddings | |
| 在未受干扰的DNA复制过程中，ATR的激活受到VCP/p97的限制，这是通过从染色质中提取DNA聚合酶α/引发酶实现的。 | Rodriguez-Acebes, S. | N/A | The activation of ATR during unperturbed DNA replication is restricted by VCP/p97 through the extraction of DNA polymerase α/Primase from chromatin | |
| 拟南芥LSM7对于生长素介导的SAUR基因调控和热形态发生是必不可少的。 | Nardeli, S. M. | N/A | Arabidopsis thaliana LSM7 is essential for auxin-mediated regulation of SAUR genes and thermomorphogenesis | |
| SMARCAD1和TOPBP1在从2C样状态向多能状态过渡时，对异染色质的维持起到了作用。 | Sebastian-Perez, R. | N/A | SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state | |
| 全脑因果发现使用fMRI | Arab, F. | N/A | Whole-Brain Causal Discovery Using fMRI | |
| 尼古丁与安慰剂口香糖对疼痛敏感性的影响及其对峰值α频率的介导作用 | Millard, S. K. | N/A | Effects of nicotine compared to placebo gum on sensitivity to pain and mediating effects of peak alpha frequency | |
| 外侧嗅周皮质通过整合视觉空间序列来支持物体感知。 | Bonnen, T. | N/A | Perirhinal cortex supports object perception by integrating over visuospatial sequences | |
| RNA G-四链体在衰老和阿尔茨海默病中的新角色 | Kallweit, L. | N/A | A New Role for RNA G-quadruplexes in Aging and Alzheimer's Disease | |
| 发声过程中对听觉反馈错误的意识和无意识感知：行为功能与事件相关电位相关性 | Suchy, D. | N/A | Conscious and unconscious perception of errors in auditory feedback during vocalization: Behavioral functions and event-related potential correlates | |
| 母体蔗糖摄入改变了母亲、胎盘和胎儿的类固醇水平。 | Seib, D. R. | N/A | Maternal sucrose consumption alters steroid levels in the mother, placenta, and fetus | |
| 海马体背腹轴上恐惧学习和恐惧表达的整合 | Pompili, M. N. | N/A | Integration of fear learning and fear expression across the dorsoventral axis of the hippocampus | |
| 利用光遗传学技术绘制小鼠纹状体中与节律性相位相关的兴奋性图谱 | Mohapatra, M. | N/A | Optogenetic mapping of rhythmic phase-dependent excitability in the mouse striatum | |
| 程序性细胞死亡与蚂蚁翅膀多态性的起源：对个体性重大进化转变的启示 | Hanna, L. | N/A | Programmed cell death and the origin of wing polyphenism in ants: implications for major evolutionary transitions in individuality | |
| MixtureFinder：用于系统发育分析的DNA混合模型估计 | Ren, H. | N/A | MixtureFinder: Estimating DNA mixture models for phylogenetic analyses | |
| VPS41的缺失会引发胰岛素储存的逐渐丧失以及β细胞身份的下调。 | Yau, B. | N/A | VPS41 deletion triggers progressive loss of insulin stores and downregulation of beta-cell identity | |
| 肝脏特异性生存运动神经元（SMN）耗竭对中枢神经系统及外周组织病理学的影响 | de Almeida, M. M. | N/A | Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology | |
| Cdbgtricks：更新压缩de Bruijn图的策略 | Hannoush, K. | N/A | Cdbgtricks: strategies to update a compacted de bruijn graph | |
| 群体认同促进大脑整合以实现集体表现 | Enhui, X. | N/A | Group identification drives brain integration for collective performance | |
| 超高剂量率氦离子束：在保持肿瘤控制的同时最小化脑组织损伤 | Dokic, I. | N/A | Ultra-High Dose Rate Helium Ion Beams: Minimizing Brain Tissue Damage while Preserving Tumor Control | |
| 未被抑制的皮层抑制性神经元集合控制着远距离记忆的提取 | Wang, S. | N/A | Unsilenced inhibitory cortical ensemble gates remote memory retrieval | |
| MLL4调控出生后腭部生长和中腭缝发育 | Lee, J.-M. | N/A | MLL4 regulates postnatal palate growth and midpalatal suture development | |
| 一种基于脉冲依赖的突触神经网络片上学习算法 | Stuck, M. | N/A | A Burst-Dependent Algorithm for Neuromorphic On-Chip Learning of Spiking Neural Networks | |
| 伏隔核中D1/D2中型多棘神经元在雄性东方田鼠配对结合形成中的不同作用 | Zhang, L. | N/A | Different Roles of D1/D2 Medium Spiny Neurons in the Nucleus Accumbens in Pair Bond Formation of Male Mandarin Voles | |
| 铜绿假单胞菌中CsoR对趋化性和铜抗性的协同调控 | He, M. | N/A | Coordinated regulation of chemotaxis and resistance to copper by CsoR in Pseudomonas putida | |
| 利用CRISPR富集的宏基因组方法增强废水样本中抗生素抗性基因的检测 | Mao, Y. | N/A | Enhanced detection for antibiotic resistance genes in wastewater samples using CRISPR-enriched metagenomic method | |
| 磷酸化和去磷酸化在Rubisco活化酶调控中的作用 | Bhatnagar, N. | N/A | The role of phosphorylation and dephosphorylation in the regulation of Rubisco activase | |
| 选择性自噬通过降解Su(var)2-10/PIAS来微调Stat92E活性，在果蝇神经胶质损伤信号传导过程中起作用。 | Vincze, V. | N/A | Selective autophagy fine-tunes Stat92E activity by degrading Su(var)2-10/PIAS during glial injury signalling in Drosophila | |
| 广泛的行为指标与大脑微观结构之间的关联在自闭症谱系障碍（ASD）中普遍存在，这表明年龄可能介导了不同亚型的ASD。 | Ressa, H. | N/A | Widespread Associations between Behavioral Metrics and Brain Microstructure in ASD Suggest Age Mediates Subtypes of ASD | |
| Megabouts：一种用于斑马鱼运动分析的灵活管道 | Jouary, A. | N/A | Megabouts: a flexible pipeline for zebrafish locomotion analysis | |
| 雌性生殖系特异性蛋白Sakura与Otu相互作用，对生殖干细胞的更新、分化及卵子发生过程至关重要。 | Azlan, A. | N/A | Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis | |
| 工作记忆从优先和非优先状态中提取的长期影响 | Born, F. | N/A | Long-Term Effects of Working Memory Retrieval From Prioritized and Deprioritized States | |
| 弓形虫引发的侵袭孔 | Kegawa, Y. | N/A | The invasion pore induced by Toxoplasma gondii | |
| 鸡盲肠微生物群落的代谢建模揭示了竞争与合作的格局 | Utkina, I. | N/A | Metabolic modeling of microbial communities in the chicken ceca reveals a landscape of competition and co-operation | |
| 利用H2在Cupriavidus necator H16中生产木糖醇 | Jämsä, T. | N/A | H2-driven xylitol production in Cupriavidus necator H16 | |
| 开发自主神经系统多尺度神经连接知识库 | Imam, F. T. | N/A | Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System | |
| 核糖体生物合成超激活与ErbB信号传导介导的网络重塑导致对FGFR2抑制的适应性抗性 | Zhang, T. | N/A | Ribosomal Biogenesis Hyperactivation and ErbB signalling Mediated Network Rewiring Causes Adaptive Resistance to FGFR2 Inhibition | |
| 离子传感器与dSarm并行作用，促进神经退行性变 | Avetisyan, A. | N/A | An Ionic Sensor acts in Parallel to dSarm to Promote Neurodegeneration | |
| 多尺度兴奋-抑制平衡动力学：整合代谢物动力学与时变执行网络 | Saviola, F. | N/A | Multiscale excitation-inhibition balance dynamics: integrating metabolite kinetics with time-varying executive networks | |
| 核糖体丰度而非旁系同源基因组成对生殖系发育至关重要 | Grobicki, K. Z. A. | N/A | Ribosome abundance, not paralogue composition, is essential for germline development | |
| 高分辨率成像图谱揭示了胰腺交感神经支配在糖尿病小鼠中的情境依赖性作用 | Xu, Q. | N/A | High-resolution imaging atlas reveals context-dependent role of pancreatic sympathetic innervation in diabetic mice | |
| 靶向激活小胶质细胞PPARδ重编程免疫代谢并增强饮食诱导肥胖中的胰岛素敏感性。 | Jiao, H. | N/A | Targeted activation of microglial PPARdelta reprograms immunometabolism and enhances insulin sensitivity in diet-induced obesity. | |
| 在问题解决过程中，眼睛和手的协同发音揭示了层次化的规划结构。 | Eluchans, M. | N/A | Eye and hand coarticulation during problem solving reveals hierarchically organized planning | |
| Lewy-MSA混合折叠驱动独特的神经元α-突触核蛋白病理 | Enomoto, M. | N/A | Lewy-MSA hybrid fold drives distinct neuronal a-synuclein pathology | |
| 将空间药物异质性与微生物生长动力学在理论和实验中联系起来 | Hu, Z. | N/A | Linking spatial drug heterogeneity to microbial growthdynamics in theory and experiment | |
| 在胚胎关键时期，线粒体活性氧的保守和HIF1-α信号传导指导随后的神经系统发育 | Sobrid-Camean, D. | N/A | Conserved mitochondrial reactive oxygen species and HIF1-alpha signalling during an embryonic critical period directs subsequent nervous system development | |
| 人类平滑受体中胆固醇感知与转运的能量学 | Bansal, P. D. | N/A | Energetics of cholesterol perception and translocation in the human Smoothened receptor | |
| 有家族性额颞叶痴呆病史的无症状个体尿蛋白的变化 | Su, Y. | N/A | Changes in urinary proteins of unaffected individuals with a family history of frontotemporal dementia | |
| 塑造发育中的小人：剥夺和补偿行为在感觉重映射中的作用 | Tucciarelli, R. | N/A | Shaping the developing homunculus: the roles of deprivation and compensatory behaviour in sensory remapping | |
| 发现一种源自SARS-CoV2 S2蛋白的肽段，具有类似超抗原的T细胞刺激特性 | Tu, T. H. | N/A | The identification of a SARs-CoV2 S2 protein-derived peptide with super-antigen-like stimulatory properties on T-cells | |
| 特定谱系驱动因子库将果蝇腹神经索中发育中的神经回路与行为联系起来。 | Soffers, J. H. | N/A | A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila Ventral Nerve Cord. | |
| 对一个由宏基因组组装的基因组进行比较基因组分析，揭示了Mucoromycotina细根内生菌根真菌中独特的共生特性 | Cole, J. | N/A | Comparative genomic analysis of a metagenome-assembled genome reveals distinctive symbiotic traits in a Mucoromycotina fine root endophyte arbuscular mycorrhizal fungus | |
| 基于人群的元蛋白质组学揭示了肠道微生物群与表型之间的功能关联 | Liang, S. | N/A | Population-based metaproteomics reveals functional associations between gut microbiota and phenotypes | |
| 通过瞬时递送CRISPR表观基因组编辑器核糖核蛋白实现可编程的表观基因组编辑 | Xu, D. | N/A | Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins | |
| 氨基酸酰基-RNA环化连接的立体选择性 | Kim, S. | N/A | Stereoselectivity of Aminoacyl-RNA Loop-closing Ligation | |
| 基因（组）重复对GPCR信号通路扩展和进化的影响 | Barradas, A. | N/A | Implications of gen(om)e duplications on the expansion and evolution of the GPCR signalling pathway | |
| 特定阶段CAR介导的信号传导从诱导多能干细胞生成类似初始状态、TCR缺失的CAR T细胞 | Yoo, S. P. | N/A | Stage-specific CAR-mediated signaling generates naive-like, TCR-null CAR T cells from induced pluripotent stem cells | |
| 聚集肠道：神经退行与细菌功能性淀粉样蛋白之间的联系 | Wojciechowska, A. W. | N/A | Aggregating gut: on the link between neurodegeneration and bacterial functional amyloids | |
| SNMF：综合学习突变特征与预测DNA修复缺陷 | Goossens, S. A. C. H. | N/A | SNMF: Integrated Learning of Mutational Signatures and Prediction of DNA Repair Deficiencies | |
| TCF3::HLF通过调控增强子-启动子网络并激活MEF2C，促进白血病中未成熟造血干细胞基因表达 | Priebe, V. | N/A | TCF3::HLF Orchestrates an Enhancer-Promoter Network with Activation of MEF2C to Promote Immature HSC gene Expression in Leukemia | |
| 分析公开可用的转录组数据以识别与骨肉瘤转移相关的关键基因和通路 | Horak, I. | N/A | Analysis of publicly available transcriptomic data to identify key genes and pathways associated with osteosarcoma metastasis | |
| Alk1在动脉内皮细胞中的缺失会导致鼻出血、脑微出血、动脉异常以及平滑肌覆盖缺陷。 | Zhang, X. | N/A | Arterial endothelial deletion of Alk1 causes epistaxis and cerebral microhemorrhage with aberrant arteries and defective smooth muscle coverage. | |
| 大豆脉坏死病毒（SVNV）蛋白的特性分析：田间株系序列分析及不同细胞类型中定位模式的比较 | Shehata, A. H. | N/A | Characterization of Soybean Vein Necrosis Virus (SVNV) Proteins: Sequence Analysis of Field Strains and Comparison of Localization Patterns in Differing Cell Types | |
| 感觉神经元中的Piezo2影响全身和脂肪组织的代谢 | Passini, F. S. | N/A | Piezo2 in sensory neurons influences systemic and adipose tissue metabolism | |
| 蚕豆耐寒性的全基因组关联研究揭示了冷季豆科植物中的同源位点，并突出了相关的候选基因 | Imbert, B. | N/A | Genome-wide association study of frost tolerance in Vicia faba reveals syntenic loci in cool-season legumes and highlights relevant candidate genes | |
| PIEZO1在完整细胞中的纳米结构和结构多样性 | Verkest, C. | N/A | Cluster nanoarchitecture and structural diversity of PIEZO1 in intact cells | |
| 使用蛋白酶体靶向纳米体偶联物降解内在无序蛋白 | Sun, X. | N/A | Degradation of intrinsically disordered proteins using proteolysis targeting nanobody conjugate | |
| 自我冷却的花朵：炎热地中海环境中夏季开花的蓟的热生态学 | Herrera, C. M. | N/A | Flowers that cool themselves: thermal ecology of summer-blooming thistles in hot Mediterranean environments | |
| 珊瑚修复只有在当地人类压力水平较低时才可行 | Brookson, C. B. | N/A | Coral restoration is only practical when local human pressure levels are low | |
| 鱼与熊掌不可兼得：在景观连通性恢复中权衡生态系统服务与生物多样性组合 | Neyret, M. | N/A | One cannot have it all: trading-off ecosystem services and biodiversity bundles in landscape connectivity restoration | |
| 与太平洋西北地区土壤中种植的优质冬豌豆品种相关的细菌群落 | Yurgel, S. | N/A | Bacterial communities associated with food-quality winter pea cultivars grown in Pacific Northwest soils | |
| 进化救援模型提供了推动癌细胞种群走向灭绝的策略。 | Dabi, A. | N/A | Evolutionary rescue model informs strategies for driving cancer cell populations to extinction | |
| 更新后的参考基因组序列和注释揭示了基因的丢失和获得，这些变化是裸鼹鼠生物学特性的基础。 | Sokolowski, D. J. | N/A | An updated reference genome sequence and annotation reveals gene losses and gains underlying naked mole-rat biology | |
| siRNA途径对埃及伊蚊转座子表达的有限影响 | Bergman, A. | N/A | Limited impact of the siRNA pathway on transposable element expression in Aedes aegypti | |
| 关联分析揭示了在茄子驯化过程中，既有人为选择事件，也有环境选择事件。 | Omondi, E. | N/A | Association analyses reveal both anthropic and environmental selective events during eggplant domestication | |
| 利用葡糖杆菌氧化菌对超镁铁质矿物的生物加速风化作用 | Lee, J. J. | N/A | Bio-Accelerated Weathering of Ultramafic Minerals with Gluconobacter oxydans | |
| 长期肘部疼痛及重复经颅磁刺激对皮层抑制作用的影响：一项TMS-EEG研究 | Chowdhury, N. | N/A | The effect of prolonged elbow pain and rTMS on cortical inhibition: A TMS-EEG study | |
| 鼠疫耶尔森菌的全球进化模式及其向非洲的传播 | Mas Fiol, G. | N/A | Global evolutionary patterns of Yersinia pestis and its spread into Africa | |
| 宫颈阴道微生物特征可预测感染女性沙眼衣原体向生殖道上部的传播 | Jeong, S. | N/A | Cervicovaginal microbial features predicts Chlamydia trachomatis spread to the upper genital tract of infected women | |
| 重复的香烟烟雾暴露会降低体外培养的人类肺成纤维细胞的增殖速率。 | Cannard, E. C. | N/A | Repeated cigarette smoke exposure attenuates the proliferation rate of primary human lung fibroblasts in vitro | |
| 使用3D-NaissI方法揭示成年心脏组织的原生结构 | PATALUCH, N. | N/A | Unveiling the native architecture of adult cardiac tissue using the 3D-NaissI method | |
| Rab2B促进伴侣蛋白介导的肌动蛋白折叠，并防止锥虫中的发育性转录重编程和静止 | Li, F.-J. | N/A | Rab2B promotes chaperonin-mediated actin folding and prevents developmental transcription reprogramming and quiescence in trypanosomes | |
| 非肌肉型α-肌动蛋白是心肌Z盘的内在组成部分，参与调节肌节周转、收缩力和心脏重塑过程。 | Hayes, J. B. | N/A | A non-muscle α-actinin is an intrinsic component of the cardiac Z-disc and regulates sarcomere turnover, contractility, and heart remodeling | |
| FIC-1介导的AMP化作用丧失会激活UPRER，并上调细胞质HSP70分子伴侣，以抑制多聚谷氨酰胺毒性。 | Van Pelt, K. M. | N/A | Loss of FIC-1-mediated AMPylation activates the UPRER and upregulates cytosolic HSP70 chaperones to suppress polyglutamine toxicity | |
| 喜马拉雅全基因组序列提供了对种群形成和适应的见解 | Arciero, E. | N/A | Himalayan whole-genome sequences provide insight into population formation and adaptation | |
| 肝细胞癌阶段特异性转录组图谱：来自超级和差生存者的见解及预后特征鉴定 | Xu, X. | N/A | Stage-Specific Transcriptome Landscape of Hepatocellular Carcinoma: Insights from Super and Poor Survivors with Prognostic Signature Identification | |
| 糖萼诱导的膜管形成 | Xiao, K. | N/A | Glycocalyx-induced formation of membrane tubes | |
| 早期生活压力的性别二态结果背后的电路机制 | Jiang, C. | N/A | Circuit mechanisms underlying sexually dimorphic outcomes of early life stress | |
| 基因组特征及多药耐药肺炎克雷伯菌株BCSIR-JUMIID的功能解析 | Ahmed, M. F. | N/A | Genomic characterization and functional insights of multidrug-resistant Klebsiella pneumoniae strain BCSIR-JUMIID | |
| Cavin1结合纳米抗体揭示了N端卷曲螺旋域的结构灵活性及其受调控的相互作用 | Gao, Y. | N/A | Cavin1 binding nanobodies reveal structural flexibility and regulated interactions of the N-terminal coiled-coil domain | |
| 使用一种新方法ARGO（Analysis of Red Green Offset），在活体中可视化突触小泡蛋白Synaptogyrin/SNG-1的周转情况 | Shiliaev, N. | N/A | Visualizing turnover of synaptic vesicle protein Synaptogyrin/SNG-1 in vivo using a new method, ARGO (Analysis of Red Green Offset) | |
| 由分布在膜表面的聚合酶驱动的肌动蛋白细丝组装 | Mullins, D. | N/A | Actin filament assembly driven by distributive polymerases clustered on membrane surfaces | |
| 依那普利通过靶向抗氧化基因，经由磷酸化Smad1/5/9来缓解衰老。 | Lyu, W. | N/A | Enalapril mitigates aging by targeting antioxidative genes via phosphorylated Smad1/5/9 | |
| 永生化的肠间质细胞——体外干细胞龛 | Canella, M. | N/A | Immortalized Intestinal Telocytes - A Stem Cell Niche In Vitro | |
| Rho效应蛋白ARHGAP18通过YAP和Merlin协调Hippo通路的反馈回路，以调节细胞骨架和上皮细胞极性。 | Murray, E. C. | N/A | The Rho effector ARHGAP18 coordinates a Hippo pathway feedback loop through YAP and Merlin to regulate the cytoskeleton and epithelial cell polarity. | |
| CRL4DCAF12对MCMBP的调控确保了DNA复制的最佳许可 | Yadav, A. K. | N/A | CRL4DCAF12 regulation of MCMBP ensures optimal licensing of DNA replication | |
| Notch信号通路在腺体干细胞/祖细胞中驱动促再生和迁移特性 | Cinat, D. | N/A | Notch Signaling Drives Pro-Regenerative and Migratory Traits in Glandular Stem/Progenitor Cells | |
| 内质网-线粒体接触结构组成的灵活性 | Covill-Cooke, C. | N/A | Compositional Flexibility of the ER-Mitochondria Encounter Structure | |
| 微管聚合和动力蛋白的抑制会损害与室管膜瘤相关的ZFTA-RELA融合蛋白的核定位及NF-κB的激活。 | Ishii, M. | N/A | Inhibition of microtubule polymerization and dynein impairs the nuclear localization of the ependymoma-associated ZFTA-RELA fusion protein and NF-κB activation | |
| HelD是一种全球转录因子，能够增强快速生长的分枝杆菌中的基因表达。 | Vankova, V. | N/A | HelD is a Global Transcription Factor Enhancing Gene Expression in Rapidly Growing Mycobacteria | |
| 通过邻近标记技术鉴定金黄色葡萄球菌与内皮细胞表面的相互作用组 | Ruhling, M. | N/A | Identification of the Staphylococcus aureus Endothelial Cell Surface Interactome by Proximity Labeling | |
| 全球丰富滤食者对原绿球藻的捕食 | Sweeney, C. | N/A | Prochlorococcus predation by a globally abundant filter feeder | |
| 细胞死亡效应下不可逆细胞分化的演变 | Gao, Y. | N/A | The evolution of irreversible cell differentiation under cell death effect | |
| 泛素对SPRTN蛋白酶的变构激活维持了基因组的稳定性 | Dürauer, S. | N/A | Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability | |
| 古HLA-B*73:01等位基因的分子特征揭示了其独特的肽展示谱及与KIR2DL2的偏倚性结合 | Ross, P. | N/A | Molecular characterization of the archaic HLA-B*73:01 allele reveals presentation of a unique peptidome and skewed engagement by KIR2DL2 | |
| 致癌性GNAQ/11诱导的IP3/钙信号通路重塑保护葡萄膜黑色素瘤免受钙驱动的细胞死亡 | Garcia, C. | N/A | Oncogenic GNAQ/11-induced remodeling of the IP3/Calcium signaling pathway protects Uveal Melanoma against Calcium-driven cell death | |
| MASLD驱动的骨丢失的性二态性 | Goldscheitter, G. M. | N/A | Sexual dimorphism of MASLD-driven bone loss | |
| 成年斯普拉格-道利大鼠中，中脑动脉反应性和血流动力学的性别差异与全身动脉硬度的变化无关 | Yamaleyeva, L. | N/A | Sex Differences in Middle Cerebral Artery Reactivity and Hemodynamics Independent from Changes in Systemic Arterial Stiffness in Adult Sprague-Dawley Rats | |
| 玉米光合性状变异的定量遗传学 | Ali, W. | N/A | Quantitative genetics of photosynthetic trait variation in maize | |
| 通过图像到图像的翻译实现无标签多重显微成像，克服像素级和图像级相似性之间的权衡 | Morikura, T. | N/A | Label-free multiplex microscopic imaging by image-to-image translation overcoming the trade-off between pixel- and image-level similarity | |
| 隐蔽的肌肉活动揭示了动态的冻结状态，并为动物的行动做好了准备。 | Hobbiss, A. F. | N/A | Covert muscle activity reveals dynamic freezing states and prepares the animal for action | |
| SMAC模拟物促使人类巨噬细胞吞噬活癌细胞 | Liu, S. Y. | N/A | SMAC mimetics induce human macrophages to phagocytose live cancer cells | |
| 用于检测耐甲氧西林金黄色葡萄球菌光谱模式时间变化的非目标筛查方法及事后峰特征描述 | Nichani, K. | N/A | Non-targeted screening method for detecting temporal shifts in spectral patterns of Methicillin Resistance Staphylococcus aureus and post-hoc description of peak features | |
| 景观中的农业实践对草原节肢动物有影响，此外还有当地条件和土地覆盖。 | Brusse, T. | N/A | Farming practices in the landscape have an impact on grassland arthropods, in addition to local conditions and land cover | |
| 与流量相关的叶片和根系性状的协调影响森林群落构建 | Ma, Z. | N/A | Coordination of flux-related leaf and root traits impacts forest community assembly | |
| 一种基于Omics的方法研究了拟南芥单个FERONIA和MARIS同源基因，证实了细胞壁完整性与脱落酸之间的联系。 | Jobe, T. O. | N/A | An Omics approach on Marchantia polymorpha single FERONIA and MARIS homologs confirms links between cell wall integrity and abscisic acid | |
| 研究寄生植物中不同寄生水平下的长链非编码RNA | Rodrigues, W. F. C. | N/A | Investigating lncRNAs at different levels of parasitism in parasitic plants | |
| 炎症小体传感器NLRP3与REV7相互作用，通过同源重组维持基因组完整性。 | Burlet, D. | N/A | The inflammasome sensor NLRP3 interacts with REV7 to maintain genome integrity through homologous recombination | |
| Lamin B1依赖性调控人类有丝分裂分离酶 | Picotto, J. | N/A | Lamin B1-dependent regulation of human separase in mitosis | |
| 利用电絮凝处理工艺对纺织印染废水进行处理和再加工 | fatima, N. | N/A | Treatment and reprocessing of textile dyeing wastewater by using the electrocoagulation treatment process | |
| 环境DNA与社区科学：城市蜻蜓调查的优势与局限 | Uche-Dike, R. | N/A | Environmental DNA vs. Community Science: Strengths and Limitations for Urban Odonata Surveys | |
| 环境DNA与社区科学：城市蜻蜓调查的优势与局限 | Uche-Dike, R. | N/A | Environmental DNA vs. Community Science: Strengths and Limitations for Urban Odonata Surveys | |
| 早期生活环境温度对野生鸟类肠道微生物群的影响？一项实验方法 | Ruuskanen, S. | N/A | The effects of early-life ambient temperature on the gut microbiome of a wild bird? an experimental approach | |
| pnetr：一个用于PnET系列森林生态系统模型的R包 | Gao, X. | N/A | pnetr: An R package for the PnET family of forest ecosystem models | |
| 鼠李半乳糖醛酸聚糖-II二聚化缺陷损害了植物中生长与粘附维持之间的协调 | Baba, A. I. | N/A | Rhamnogalacturonan-II dimerization deficiency impairs the coordination between growth and adhesion maintenance in plants | |
| 基于无人机的多光谱成像技术在洪涝耐受玉米品种识别中的应用：一个真实世界的案例研究 | Mitchell, M. N. | N/A | Drone-Based Identification of Flood-Tolerant Maize via Multispectral Imaging: A Real-World Case Study | |
| BPMs通过促进Aux/IAA蛋白IAA10的非生长素依赖性降解来调控拟南芥幼苗的发育。 | Ban, Z. | N/A | BPMs regulate Arabidopsis seedling development by promoting auxin-independent degradation of the Aux/IAA protein IAA10 | |
| 局部无序与工程光开关中增强的催化作用相关 | McCormick, J. W. | N/A | Local disorder is associated with enhanced catalysis in an engineered photoswitch | |
| 背外侧前额叶皮层通过优化长期策略提取来驱动战略性放弃 | Noel, J.-P. G. | N/A | Dorsolateral prefrontal cortex drives strategic aborting by optimizing long-run policy extraction | |
| 一种自动的、通用的错误信号在不同任务间共享，并预测不同感觉模态的置信度。 | Davidson, M. J. | N/A | An automatic domain-general error signal is shared across tasks and predicts confidence in different sensory modalities | |
| 饥饿对雄性和雌性小鼠的趋避行为有不同的影响 | Anversa, R. G. | N/A | Hunger alters approach-avoidance behaviours differently in male and female mice | |
| 评估利用磁共振成像（MRI）测量人脑中脑脊液（CSF）动力学全谱新方法的可行性：来自模拟研究的见解 | van der Voort, E. | N/A | Assessing the feasibility of a new approach to measure the full spectrum of CSF dynamics within the human brain using MRI: insights from a simulation study | |
| 大黄蜂对氨基酸的味觉敏感性 | Rossoni, S. | N/A | Gustatory sensitivity to amino acids in bumblebees | |
| 功能成熟与经验依赖性可塑性在成年新生嗅球多巴胺能神经元中 | Tufo, C. | N/A | Functional maturation and experience-dependent plasticity in adult-born olfactory bulb dopaminergic neurons | |
| 赛洛西宾-NMDAR调节剂给药的协同行为与神经可塑性效应。 | Ben Tal, T. | N/A | Synergistic Behavioral and Neuroplastic Effects of Psilocybin-NMDAR Modulator Administration. | |
| 胆碱能信号在多感官伽马刺激诱导的淀粉样蛋白周围血管清除中的作用 | Lavoie, N. S. | N/A | The role of cholinergic signaling in multi-sensory gamma stimulation induced perivascular clearance of amyloid | |
| 通过综合应激反应感知胞外L-脯氨酸的可用性决定细胞竞争的结果。 | Krishnan, S. | N/A | Sensing of extracellular L-Proline availability by the integrated stress response determines the outcome of cell competition. | |
| 草履虫的群集行为 | Tabata, T. | N/A | The swarming behaviors of Vorticella | |
| 行动中规划：解决顺序实体任务中规划与行动的连续动态问题 | Nuzzi, D. | N/A | Planning-while-acting: addressing the continuous dynamics of planning and action in a sequential embodied task | |
| 对未来的认知：海豚知道何时需要为未来记住某些事情。 | Ortiz, S. T. | N/A | Awareness of the future: Dolphins know when they need to remember for the future | |
| 双向响应的温度感受器编码冷和暖 | Bokiniec, P. | N/A | Bidirectionally responsive thermoreceptors encode cool and warm | |
| 正常衰老过程中脑血流量和葡萄糖代谢率在性别上的差异及其关联性。 | Deery, H. | N/A | Sex differences in the rates and association of cerebral blood flow and glucose metabolism in normative ageing. | |
| GABA与谷氨酰胺-谷氨酸动态的解耦及其在触觉感知中的作用：一项fMRS研究 | Pasanta, D. | N/A | Decoupling of GABA and Glutamine-Glutamate Dynamics and their role in tactile perception: An fMRS Study | |
| 高维数据空间中或多或少存在潜在变量？这正是问题的关键所在。 | Vaccari, F. E. | N/A | More or less latent variables in the high-dimensional data space? That is the question | |
| 海马CA2神经元不成比例地表达AAV递送的遗传物质 | Alexander, G. | N/A | Hippocampal CA2 neurons disproportionately express AAV-delivered genetic cargo | |
| 兴奋性和抑制性细胞的层依赖比率如何塑造平衡网络中的皮层编码 | Alizadeh, A. | N/A | How the layer-dependent ratio of excitatory to inhibitory cells shapes cortical coding in balanced networks | |
| 癫痫持续时间中的周期及其在破伤风毒素大鼠模型中的潜在动态 | Zarei Eskikand, P. | N/A | Cycles in Seizure Duration and Their Underlying Dynamics in the Tetanus Toxin Rat Model | |
| 异甘草素减轻了链脲佐菌素诱导的阿尔茨海默病小鼠模型中的认知障碍、脑内tau蛋白磷酸化及氧化应激。 | Tang, Z. | N/A | Isoliquiritigenin attenuated cognitive impairment, cerebral tau phosphorylation and oxidative stress in a streptozotocin-induced mouse model of Alzheimers disease | |
| st-DenseViT：一种用于动态脑网络密集预测的弱监督时空视觉Transformer | Kazemivash, B. | N/A | st-DenseViT: A Weakly Supervised Spatiotemporal Vision Transformer for Dense Prediction of Dynamic Brain Networks | |
| 静息态功能连接和快速纺锤波的时间组织有助于健康老化中的情景记忆巩固 | Hamel, A. | N/A | Resting-state functional connectivity and fast spindle temporal organization contribute to episodic memory consolidation in healthy aging | |
| 光遗传学操控细胞核背侧蛋白揭示了转录的时间需求及后果 | Pimmett, V. L. | N/A | Optogenetic manipulation of nuclear Dorsal reveals temporal requirements and consequences for transcription | |
| P300/CBP催化的乙酰化通过激活DUX来保护次级合子基因组激活 | Xiao, L. | N/A | p300/CBP-catalyzed acetylation safeguards minor zygotic genome activation via activating DUX | |
| 好斗的冲突会影响沙漠蚂蚁的归巢路径整合 | Bollig, A. | N/A | Aggressive conflict impacts path integration in homing desert ants | |
| 一种用于生物分子凝聚物模拟的无序RNA粗粒度模型 | Yasuda, I. | N/A | A coarse-grained model of disordered RNA for simulations of biomolecular condensates | |
| 通过多站点DMS探针在活细胞中同时映射RNA的二级、三级和四级结构 | Saleem, I. | N/A | Simultaneous mapping of RNA secondary, tertiary, and quaternary structure in living cells by multi-site DMS probing | |
| IL-33/ST2信号轴在急性SARS-CoV-2感染中的发病机制中起驱动作用 | Fleming, C. | N/A | The IL-33/ST2 signaling axis drives pathogenesis in acute SARS-CoV-2 infection | |
| 在合成人类肠道微生物群落中发现替代稳定状态 | Garza, D. R. | N/A | Discovery of alternative stable states in a synthetic human gut microbial community | |
| 广泛保守的新型色素产生在枯草芽孢杆菌物种中的特征描述 | Stannius, R. O. | N/A | Characterization of widely conserved novel pigment production in Bacillus subtilis species | |
| 真核生物核糖体中药物结合残基的自然变异 | Chan, L. I. | N/A | Natural variation of the drug-binding residues in eukaryotic ribosomes | |
| 衣原体对兼性宿主多细胞性的适应 | Helmlinger, L. | N/A | The adaptation of chlamydiae to facultative host multicellularity | |
| 揭示单一人皮肤部位共生棒状杆菌的多样性 | Thomas, G. H. | N/A | Revealing the diversity of commensal corynebacteria from a single human skin site | |
| 折叠稀释和稀释液体积对细菌培养中菌落形成单位估计的影响 | Jain, M. | N/A | The impact of fold-dilution and diluent volume on the estimation of colony forming units in a bacterial culture | |
| snRNA输出复合物协同组装的结构基础 | Dubiez, E. | N/A | Structural basis for the synergistic assembly of the snRNA export complex | |
| 基因组中转换突变频率高于颠换突变的证据：基于密度泛函理论的碱基对结合能计算 | Deka, N. | N/A | Higher frequency of transition mutation over transversion mutation in genomes: evidence from the binding energy calculation of base pairs using DFT | |
| 用于下一代测序应用的果蝇总RNA中高效去除核糖体RNA | Koppaka, O. | N/A | EFFICIENT RIBOSOMAL RNA DEPLETION FROM DROSOPHILA TOTAL RNA FOR NEXT-GENERATION SEQUENCING APPLICATIONS | |
| piRNA通路介导了Aedes蚊子体细胞和生殖细胞中LTR逆转录转座子的转录沉默。 | Taskopru, E. | N/A | The piRNA pathway mediates transcriptional silencing of LTR retrotransposons in the soma and germline of Aedes mosquitoes | |
| 遗传性出血性毛细血管扩张症动静脉畸形中PIEZO1的过度表达 | Park, H. | N/A | PIEZO1 overexpression in hereditary hemorrhagic telangiectasia arteriovenous malformations | |
| 系统探索NOD样受体中的域组合，揭示了Sordariales真菌中两种类型的NACHT域 | bonometti, l. | N/A | Systematic exploration of domain assortments in NOD-like receptors uncovers two types of NACHT domains in Sordariales fungi | |
| 人类多能干细胞系中转录基因调控的全基因组单细胞CRISPRi图谱 | Feng, C. | N/A | A genome-scale single cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines | |
| 通过CRISPR/Cas9和多个重组腺相关病毒（rAAV）高效创建和表征多千碱基敲入 | Sentmanat, M. F. | N/A | Efficient creation and characterization of multi-kilobase knockins by CRISPR/Cas9 and multiple rAAVs | |
| 达卡市内河流微生物群落的时间和空间分布 | ALOM, M. M. | N/A | Temporal and spatial distribution of microbial community in urban river in Dhaka | |
| 基因组组织与CUT&Tag（GO-CaT）技术识别了发育中人脑神经元中与核膜相关域的亚结构及其成熟过程 | Zhang, C. | N/A | Genome Organization with CUT and Tag (GO-CaT) identifies substructure and maturation of lamina-associated domains in neurons of the developing human brain | |
| 从头非分隔化微生物用于纳米抗体的定向进化 | Wu, D. | N/A | De novo non-compartmentalized microorganism for directed evolution of nanobodies | |
| 一类依赖结合蛋白的溶质转运蛋白，以百日咳博德特氏菌中的TAXI-GltS系统为例 | Jaques, L. M. | N/A | A new class of binding protein-dependent solute transporter exemplified by the TAXI-GltS system from Bordetella pertussis | |
| 细菌磷脂酰胆碱N-甲基转移酶合成磷脂酰胆碱的结构基础 | Watanabe, Y. | N/A | Structural basis for phosphatidylcholine synthesis by bacterial phospholipid N-methyltransferases | |
| 结合糖苷酶与纳米孔技术进行糖链测序 | Gao, Z. | N/A | Combining Glycosidases and Nanopore Technology for Glycan Sequencing | |
| 对秀丽隐杆线虫中随年龄变化的胞外囊泡蛋白的元分析 | Bhunia, P. K. | N/A | A meta-analysis of age-dependent changes in extracellular vesicle proteins in C. elegans | |
| 一种具有广泛底物谱的LarA消旋酶的催化及底物特异性的结构基础 | Gatreddi, S. | N/A | Structural Basis for Catalysis and Substrate Specificity of a LarA Racemase with a Broad Substrate Spectrum | |
| 肠道微生物群衍生的GlcNAc-MurNAc是一种TLR4激动剂，能够保护宿主肠道。 | Li, C. | N/A | Gut microbiota-derived GlcNAc-MurNAc is a TLR4 agonist that protects the host gut | |
| 使用CRISPR-Cas12a实现读出的抗逆转录病毒药物快速酶学检测 | Singh, M. A. | N/A | Rapid enzymatic assay for antiretroviral drug monitoring using CRISPR-Cas12a enabled readout | |
| 建模和测量密码子使用如何调节细菌中蛋白质过表达过程中负担与产量之间的关系 | Roots, C. T. | N/A | Modeling and measuring how codon usage modulates the relationship between burden and yield during protein overexpression in bacteria | |
| 重新利用的STAT3抑制剂乙胺嘧啶可控制分枝杆菌感染引起的血管通透性和分枝杆菌负荷 | Han, D. J. | N/A | The repurposed STAT3 inhibitor pyrimethamine controls mycobacterial infection-induced vascular permeability and mycobacterial burden | |
| 合作簇结合调控了烟曲霉铁调节因子HapX在铁饥饿、充足和过量条件下的功能转换，以适应这些不同的铁环境。 | Oberegger, S. | N/A | Cooperative cluster-binding regulates the functional transitions of the Aspergillus fumigatus iron regulator HapX for adaptation to iron starvation, sufficiency and excess | |
| 双向互动对双人踝关节和腕关节追踪的影响 | Short, M. R. | N/A | Effects of Uni- and Bidirectional Interaction During Dyadic Ankle and Wrist Tracking | |
| NoButter：一个用于减少CosMx空间分子成像数据中转录本分散的R包 | O'Hora, B. | N/A | NoButter: An R package for reducing transcript dis-persion in CosMx Spatial Molecular Imaging Data | |
| OmniSegger：一种用于细菌细胞延时图像分析的管道 | Lo, T. W. | N/A | OmniSegger: A time-lapse image analysis pipeline for bacterial cells | |
| 协同多重相互作用介导伴侣蛋白HtrA1对α-突触核蛋白聚集的有效抑制 | Chinchilla, P. | N/A | Synergistic Multi-Pronged Interactions Mediate the Effective Inhibition of Alpha-Synuclein Aggregation by the Chaperone HtrA1 | |
| 通过冷冻电子断层扫描技术揭示表皮生长因子受体在细胞外囊泡中的结构与组织 | Gonzalez-Magaldi, M. | N/A | Structure and organization of full-length Epidermal Growth Factor Receptor in extracellular vesicles by cryo-electron tomography | |
| D-葡萄糖醛酸C5-差向异构酶通过结合EGFR抑制肾脏纤维化 | Jing, X. | N/A | D-glucuronyl C5-epimerase binds to EGFR to suppress kidney fibrosis | |
| 设计针对肽-MHC-I复合物的高特异性结合剂 | Liu, B. | N/A | Design of high specificity binders for peptide-MHC-I complexes | |
| 氮素富集改变了根瘤菌基因的选择 | Hill, C. A. | N/A | Nitrogen enrichment alters selection on rhizobial genes | |
| 用于骨软骨界面再生工程的具有受控矿物梯度水凝胶的高级生物打印 | Zhao, X. | N/A | Advanced Bioprinting of Hydrogels with Controlled Mineral Gradients for Regenerative Engineering of the Osteochondral Interface | |
| EasyPubPlot：一个用于快速组学数据探索和可视化的闪亮网络应用程序 | Tien, N. T. N. | N/A | EasyPubPlot: a shiny web application for rapid omics data exploration and visualization | |
| Brisk：精确的资源高效型k-mer字典 | Smith, C. | N/A | Brisk: Exact resource-efficient dictionary for k-mers | |
| 分子动力学语言模型 | Murtada, M. H. | N/A | Language Models for Molecular Dynamics | |
| 加速全基因组比对在全基因组组装时代的重要性 | Chandra, G. | N/A | Accelerating whole-genome alignment in the age of complete genome assemblies | |
| CASTER-DTA：用于预测药物-靶点亲和力的等变图神经网络 | Kumar, R. | N/A | CASTER-DTA: Equivariant Graph Neural Networks for Predicting Drug-Target Affinity | |
| FIDDLE：一种从串联质谱预测化学公式的深度学习方法 | Hong, Y. | N/A | FIDDLE: a deep learning method for chemical formulas prediction from tandem mass spectra | |
| G蛋白抑制剂YM-254890是一种别构粘合剂。 | Trent, T. | N/A | The G protein inhibitor YM-254890 is an allosteric glue | |
| 一个注释详尽的三阴性乳腺癌患者来源异种移植瘤生物库，包含未经治疗的初始样本以及在新辅助化疗全程中的纵向样本。 | Rinkenbaugh, A. L. | N/A | An annotated biobank of triple negative breast cancer patient-derived xenografts featuring treatment-naive and longitudinal samples throughout neoadjuvant chemotherapy | |
| 粘附-悬浮塑性促进循环肿瘤细胞的传播和定植 | Huh, H. D. | N/A | Adherent-suspension plasticity promotes the dissemination and colonization of circulating tumor cells | |
| 含爱泼斯坦-巴尔病毒产物的外泌体促进鼻咽癌中与白血病抑制因子相关的巨噬细胞免疫抑制极化 | Liu, T.-T. | N/A | Epstein-Barr viral product-containing exosome facilitates LIF-associated immunosuppressive polarization of macrophage in nasopharyngeal carcinoma | |
| # BioRxiv 2024-11-27 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 全基因组CRISPR筛选识别出由LRRK2调控的人类神经元摄取细胞外tau的途径 | Evans, L. D. | N/A | Whole genome CRISPR screens identify a LRRK2-regulated pathway for extracellular tau uptake by human neurons | |
| 一个长达二十年的淡水湖泊微生物时间序列，介绍了limony和TYMEFLIES数据集。 | Rohwer, R. R. | N/A | A two-decade microbial time series from a freshwater lake, introducing the limony and TYMEFLIES datasets | |
| 一种新的先验实用可辨识性方法 | Thompson, P. A. | N/A | A new method for a priori practical identifiability | |
| 在清醒状态下通过致幻剂5-MeO-DMT诱导小鼠进入类似睡眠的状态 | Breant, B. J. | N/A | Sleep-like state during wakefulness induced by psychedelic 5-MeO-DMT in mice | |
| 非转基因动物中非侵入性光学合成听觉感觉 | Tamai, Y. | N/A | Non-invasive optical synthetization of hearing sensation in non-genetically modified animal | |
| 内胚层细胞通过运动接触抑制来实现斑马鱼原肠胚形成期间均匀的细胞分散。 | LaBelle, J. | N/A | Endodermal cells use contact inhibition of locomotion to achieve uniform cell dispersal during zebrafish gastrulation | |
| 亲吻素纤维及其受体分布分析表明其在中枢感觉处理和行为状态控制中的潜在作用 | Zhang, L. | N/A | Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control | |
| ATP爆发是耻垢分枝杆菌抗生素致死性的主要驱动力。 | Lodhiya, T. | N/A | ATP burst is the dominant driver of antibiotic lethality in Mycobacterium smegmatis | |
| 系统性4-1BB刺激在疟原虫感染期间增强了滤泡外记忆B细胞的形成和回忆反应。 | Caloba, C. | N/A | Systemic 4-1BB stimulation augments extrafollicular memory B cell formation and recall responses during Plasmodium infection. | |
| bamSliceR：一个用于快速跨队列变异分析的Bioconductor包 | Huang, Y. P. | N/A | bamSliceR: a Bioconductor package for rapid, cross-cohort variant analysis | |
| GFETM：基于基因组基础的嵌入式主题模型用于单细胞ATAC-seq建模 | Fan, Y. | N/A | GFETM: Genome Foundation-based Embedded Topic Model for scATAC-seq Modeling | |
| 单分子直接RNA测序揭示了跨多个物种的表观转录组塑造 | Xie, Y.-Y. | N/A | Single-Molecule Direct RNA Sequencing Reveals the Shaping of Epitranscriptome Across Multiple Species | |
| 利用适应度景观建模和强化学习加速蛋白质工程 | Sun, H. | N/A | Accelerating protein engineering with fitness landscape modeling and reinforcement learning | |
| 细胞壁重塑和囊泡产生的维持在结核分枝杆菌中是相互关联的。 | Salgueiro, V. | N/A | Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis | |
| 干扰抑制仅在视网膜坐标中运作。 | Ilksoy, Y. A. | N/A | Distractor suppression operates exclusively in retinotopic coordinates | |
| Voronota-LT：高效、灵活且考虑溶剂的基于镶嵌分析的原子相互作用 | Olechnovic, K. | N/A | Voronota-LT: efficient, flexible and solvent-aware tessellation-based analysis of atomic interactions | |
| 利用农畜的表观基因组数据注释和评估调控区域中的功能性变异 | Ma, R. | N/A | Annotation and assessment of functional variants in regulatory regions using epigenomic data in farm animals | |
| 弯曲DNA会增加其螺旋重复 | Chandrasekhar, S. | N/A | Bending DNA increases its helical repeat | |
| Hist2Cell：从组织学图像中解析细粒度的细胞结构 | ZHAO, W. | N/A | Hist2Cell: Deciphering Fine-grained Cellular Architectures from Histology Images | |
| 一种混合效应相似性矩阵回归模型（SMRmix），用于在群落水平上整合多个微生物组数据集 | He, M. | N/A | A Mixed Effect Similarity Matrix Regression Model (SMRmix) for Integrating Multiple Microbiome Datasets at Community Level | |
| 使用蛋白质三维二级结构预测转录因子 | Liebold, J. | N/A | Transcription factor prediction using protein 3Dsecondary structures | |
| 次优的再喂养补偿了幼年营养不良小鼠模型中的生长迟缓 | Thoumas, J.-L. | N/A | Suboptimal refeeding compensates stunting in a mouse model of juvenile malnutrition | |
| 睫状蛋白IFT88的时间性消融改变了正常的脑波模式 | Strobel, M. R. | N/A | Temporal Ablation of the Ciliary Protein IFT88 Alters Normal Brainwave Patterns | |
| 评估在快速并行视觉呈现后形态-正字法、词汇和语法处理的时间进程：一项针对英语的脑电图研究。 | Dunagan, D. | N/A | Evaluating the timecourses of morpho-orthographic, lexical, and grammatical processing following rapid parallel visual presentation: an EEG investigation in English. | |
| 肠道菌群失调不可避免，但耐受性并非如此：小鼠微生物群在维持其丁酸盐生产能力的时间反应与对慢性吗啡的持续抗痛觉相关。 | Sall, I. J. | N/A | Gut dysbiosis was inevitable, but tolerance was not: temporal responses of the murine microbiota that maintain its capacity for butyrate production correlate with sustained antinociception to chronic morphine | |
| Tol-Pal复合体在细菌外膜脂质稳态中的主要作用 | Tan, W. B. | N/A | Primary role of the Tol-Pal complex in bacterial outer membrane lipid homeostasis | |
| 在高风险乳腺癌中，通过甘草查尔酮A重新编程SREBP1依赖的脂质生成和炎症：癌症预防的新途径 | Hajirahimkhan, A. | N/A | Reprogramming SREBP1-dependent lipogenesis and inflammation in high-risk breast with licochalcone A: a novel path to cancer prevention | |
| 可溶性免疫介质协调了结核分枝杆菌复合群各系之间保护性的体外肉芽肿反应。 | Arbues, A. | N/A | Soluble immune mediators orchestrate protective in vitro granulomatous responses across Mycobacterium tuberculosis complex lineages | |
| 解决分布不匹配问题以实现有效的半监督神经元分割 | Zhang, Y. | N/A | Addressing Distribution Mismatch for Effective Semi-Supervised Neuron Segmentation | |
| 神经影像去噪器，用于去除功能成像中瞬时荧光信号的噪声。 | Weissbach, S. | N/A | Neuroimage Denoiser for removing noise from transient fluorescent signals in functional imaging. | |
| 无损时空分辨率的多光谱活细胞成像 | Kumar, A. | N/A | Multispectral live-cell imaging with uncompromised spatiotemporal resolution | |
| 自适应渐渗分类方法的性能评估 | Romieu, J. | N/A | Performance evaluation of adaptive introgression classification methods | |
| 同化型NADPH依赖性亚硫酸盐还原酶的二聚化揭示了在最小界面上结合双黄素还原酶的元素 | Ghazi Esfahani, B. | N/A | Dimerization of assimilatory NADPH-dependent sulfite reductase reveals elements for diflavin reductase binding at a minimal interface | |
| 二聚化同化NADPH依赖性亚硫酸盐还原酶的结构揭示了双黄素还原酶结合的最小界面 | Ghazi Esfahani, B. | N/A | Structure of dimerized assimilatory NADPH-dependent sulfite reductase reveals the minimal interface for diflavin reductase binding | |
| 发现猴痘病毒H3中的硫酸乙酰肝素结合域作为抗痘病毒药物靶点：结合AI与MD模拟 | Zheng, B. | N/A | Discovery of a Heparan Sulfate Binding Domain in Monkeypox Virus H3 as an Anti-poxviral Drug Target Combining AI and MD Simulations | |
| 多样本非负空间分解 | Wang, Y. | N/A | Multi-sample non-negative spatial factorization | |
| 早期繁殖选择导致果蝇种群加速衰老和广泛代谢重塑 | Hubert, D. L. | N/A | Selection for early reproduction leads to accelerated aging and extensive metabolic remodeling in Drosophila melanogaster populations | |
| DNA序列的二维表示显示，大多数转换是与复制滑移相关的错配核苷酸。 | Erives, A. J. | N/A | 2D representations of DNA sequence show that most transversions are misaligned nucleotides associated with replication slippage. | |
| 婴儿脑电微状态动力学与在自然情境下与照顾者玩耍时婴儿注意力的细微模式相关 | Bagdasarov, A. | N/A | Infant EEG microstate dynamics relate to fine-grained patterns of infant attention during naturalistic play with caregivers | |
| 全面化学分型和七种kisspeptin能神经元群体在小鼠大脑中的性腺调节 | Hernandez, V. S. | N/A | Comprehensive chemotyping, and the gonadal regulation, of seven kisspeptinergic neuronal populations in the mouse brain | |
| 在形成、迁移和融合过程中，对三维肿瘤球体结构变化的非破坏性原位监测 | Ning, K. | N/A | Non-destructive in situ monitoring of structural changes of 3D tumor spheroids during the formation, migration, and fusion process | |
| 厌氧消化菌群中的代谢分离与功能基因簇 | Wang, Y. | N/A | Metabolic Segregation and Functional Gene Clusters in Anaerobic Digestion Consortia | |
| 土壤微生物群落的持久性遗留效应有助于植物适应干旱反应 | Ginnan, N. A. | N/A | Persistent legacy effects on soil microbiota facilitate plant adaptive responses to drought | |
| 揭示Galectin-1与脂质膜结合的GM1特异性 | Scollo, F. | N/A | Unraveling the GM1 specificity of Galectin-1 binding to lipid membranes | |
| 在语言产生和理解过程中，前颞叶皮层中与语音学相关的特定一致性脑信号。 | Dmitrieva, X. | N/A | Congruent brain signatures specific to phonology in fronto-temporal cortex during language production and understanding. | |
| Unipept在2024年：扩展的宏蛋白质组学分析，支持遗漏切割、半胰蛋白酶和非胰蛋白酶肽段 | Vande Moortele, T. | N/A | Unipept in 2024: Expanding metaproteomics analysis with support for missed cleavages, semi-tryptic and non-tryptic peptides | |
| 在基于模拟的历史人口遗传数据推断中，更优的置信区间 | Rousset, F. | N/A | Better confidence intervals in simulation-based inference of historical demography from population genetic data | |
| 近北极地区的蝙蝠（Myotis bats）广泛的长寿与DNA病毒驱动的适应性 | Vazquez, J. M. | N/A | Extensive longevity and DNA virus-driven adaptation in nearctic Myotis bats | |
| 非协变存储效应：平衡和正向定向选择对突变等位基因的影响，这些等位基因放大了随机适应性和人口波动 | Kim, Y. | N/A | Noncovarying storage effect: balancing and positive directional selection on mutant alleles that amplify random fitness and demographic fluctuations | |
| 稳定性与灵活性：在计算机中重塑古菌膜 | Amaral, M. | N/A | Stability vs flexibility: reshaping archaeal membranes in silico | |
| 先天抗病毒系统是鲍曼不动杆菌中驱动前噬菌体分布的主要防御系统组成部分。 | Moreno-Rodriguez, A. | N/A | Innate antiviral systems are major defensome components that drive prophage distribution in Acinetobacter baumannii | |
| PSTP：通过迁移学习和注意力机制解码蛋白质相分离的潜在序列语法 | Feng, M. | N/A | PSTP: Decoding Latent Sequence Grammar for Protein Phase Separation through Transfer Learning and Attention | |
| 一种定义细胞类型特异性CTCF结合和染色质组织的基因组范围代码 | Do, C. | N/A | A genome wide code to define cell-type specific CTCF binding and chromatin organization | |
| 肿瘤缺氧细胞外囊泡为三阴性乳腺癌创造了一个保护性微环境 | Pachane, B. C. | N/A | Tumoral hypoxic extracellular vesicles create a protective microenvironment for triple-negative breast cancer | |
| 全息显微镜揭示了在血管内皮化过程中，无需标记的内皮细胞定量动态变化。 | Leineweber, W. D. | N/A | Holotomographic microscopy reveals label-free quantitative dynamics of endothelial cells during endothelialization | |
| PLM-interact：扩展蛋白质语言模型以预测蛋白质-蛋白质相互作用 | Liu, D. | N/A | PLM-interact: extending protein language models to predict protein-protein interactions | |
| 线粒体的不均等分配在神经发生过程中促进不对称命运 | Bunel, B. | N/A | Unequal mitochondrial segregation promotes asymmetric fates during neurogenesis | |
| 晚更新世巴西东南部灰侏儒鹿摄食策略的千年尺度稳定性。 | Hubbe, A. | N/A | Late Quaternary millennial-scale stability of the feeding strategy of the gray brocket deer in Southeastern Brazil. | |
| 稀疏矩阵分解能够稳健地处理全基因组关联研究（GWAS）中样本共享的问题，从而揭示出可解释的遗传成分。 | Omdahl, A. R. | N/A | Sparse matrix factorization robust to sample sharing across GWAS reveals interpretable genetic components | |
| 发育阶段和细胞环境决定Ezh2Y641F突变在造血中的致癌和分子结果 | Zimmerman, S. M. | N/A | Developmental Stage and Cellular Context Determine Oncogenic and Molecular Outcomes of Ezh2Y641F Mutation in Hematopoiesis | |
| AlphaFold 对全基因组的预测概览 | Cazals, F. | N/A | AlphaFold predictions on whole genomes at a glance | |
| 通过原位多聚腺苷酸化和空间RNA测序实现微生物群-宿主相互作用的高分辨率空间映射 | Ntekas, I. | N/A | High Resolution Spatial Mapping of Microbiome-Host Interactions via in situ Polyadenylation and Spatial RNA Sequencing | |
| 大肠杆菌细胞宽度稳态和膨胀动力学的力学机制：MreB和隔膜抑制的影响 | Kale, T. | N/A | Mechanics of E. coli cell width homeostasis and bulging dynamics from MreB and septum inhibition | |
| 通过化学物质灌注去除兔心脏中的DNA含量，同时保持胶原蛋白和糖胺聚糖不变。 | Seitzhaparova, B. | N/A | Perfusion via chemicals removes the DNA content of rabbit hearts while keeping the collagen and glycosaminoglycan unaltered | |
| 结核分枝杆菌中一种新型放线菌特异性核糖体休眠因子 | Majumdar, S. | N/A | A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis | |
| 汉密尔顿法则的一般版本 | van Veelen, M. | N/A | The general version of Hamilton's rule | |
| 在人类细胞中表达重组人谷氨酰化TTLLs会导致不同的微管谷氨酰化模式，只有TTLL6会破坏微管动力学。 | Al Kabbani, M. A. | N/A | Expression of recombinant human glutamylating TTLLs in human cells leads to differential tubulin glutamylation patterns, with only TTLL6 disrupting microtubule dynamics | |
| 量子自旋共振在工程化磁敏荧光蛋白中的应用，使得活细胞内的多模态传感成为可能 | Abrahams, G. J. | N/A | Quantum Spin Resonance in Engineered Magneto-Sensitive Fluorescent Proteins Enables Multi-Modal Sensing in Living Cells | |
| 多个冗余的羧酸转运蛋白支持恶性疟原虫的线粒体代谢 | Rajaram, K. | N/A | MULTIPLE, REDUNDANT CARBOXYLIC ACID TRANSPORTERS SUPPORT MITOCHONDRIAL METABOLISM IN PLASMODIUM FALCIPARUM | |
| 细菌RNA中假尿苷的定量图谱 | Sharma, S. | N/A | Quantitative mapping of pseudouridines in bacteria RNA | |
| PyRID：一个用Python编写的反应性粒子和相互作用粒子的布朗动力学模拟器 | Becker, M. | N/A | PyRID: A Brownian dynamics simulator for reacting and interacting particles written in Python | |
| NaviNIBS：一个全面且开源的软件工具箱，用于神经导航的无创脑刺激。 | Cline, C. C. | N/A | NaviNIBS: a comprehensive and open-source software toolbox for neuronavigated noninvasive brain stimulation. | |
| 剥脱性青光眼中的线粒体和微管缺陷 | Venkatesan, A. | N/A | Mitochondrial and Microtubule Defects in Exfoliation Glaucoma | |
| 血小板因子4（PF4）调节造血干细胞衰老 | Zhang, S. | N/A | Platelet Factor 4 (PF4) Regulates Hematopoietic Stem Cell Aging | |
| 利用杆状病毒载体成功递送CRISPR-Cas9至昆虫脑部目标 | Dogan, B. E. K. | N/A | Successful delivery of CRISPR-Cas9 with a baculovirus vector for insect brain targets | |
| TimeFlies：一种用于果蝇头部衰老时钟的snRNA-seq技术揭示了性别偏向的衰老现象 | Tennant, N. | N/A | TimeFlies: an snRNA-seq aging clock for the fruit fly head sheds light on sex-biased aging | |
| 经过工程改造的CRISPR-碱基编辑器：家族性自主神经功能异常的永久性治疗方法 | Yun, S. | N/A | Engineered CRISPR-Base Editors as a Permanent Treatment for Familial Dysautonomia | |
| 跑步机速度在步态周期内变化引起的四肢协调变化 | Hall, B. L. | N/A | Changes in interlimb coordination induced by within-stride changes in treadmill speed | |
| 天生相连：婴儿是否已经具备与成人相似的多尺度连接网络？ | Bajracharya, P. | N/A | Born Connected: Do Infants Already Have Adult-Like Multi-Scale Connectivity Networks? | |
| 快速语义处理：一项关于叙事文本阅读的MEG研究 | Neklyudova, A. | N/A | Rapid Semantic Processing: An MEG Study of Narrative Text Reading | |
| 感觉运动同步经颅磁刺激（seTMS）能够增强运动皮层的兴奋性。 | Ross, J. M. | N/A | Sensory Entrained TMS (seTMS) enhances motor cortex excitability | |
| 瞳孔大小变化揭示了认知算术中的贝叶斯推理 | Zenon, A. | N/A | Pupil size variations reveal Bayesian inference in cognitive arithmetic | |
| Rac1抑制可预防转甲状腺素蛋白淀粉样变多发性神经病变中的轴突细胞骨架功能障碍 | Magalhaes, J. | N/A | Rac1 inhibition prevents axonal cytoskeleton dysfunction in Transthyretin Amyloid Polyneuropathy | |
| 个体差异在音乐熟悉度和音乐特征对放松时大脑活动的影响中的作用 | Scarratt, R. J. | N/A | Individual differences in the effects of musical familiarity and musical features on brain activity during relaxation | |
| 化学标记法：一种通过体内钙成像识别细胞类型的化学遗传学方法 | Ko, B. | N/A | Chemotagging: a chemogenetic approach for identifying cell types with in vivo calcium imaging | |
| 不同他汀类药物对亚麻醉氯胺酮抗运动障碍活性的影响存在差异 | Bartlett, M. J. | N/A | Differential effects of statins on the anti-dyskinetic activity of sub-anesthetic ketamine | |
| 通过长程连接在皮层区域之间建立动态共识 | Javadzadeh, M. | N/A | Dynamic consensus-building between neocortical areas via long-range connections | |
| 利用功能性超声成像技术探索乌鸦听觉端脑中的神经动力学 | Liao, D. A. | N/A | Exploring Neural Dynamics in the Auditory Telencephalon of Crows using Functional Ultrasound Imaging | |
| 白质高信号和小型塑料颗粒 | Bearer, E. L. | N/A | White matter hyperintensities and microplastics | |
| 白质微观结构与青少年、中年和晚年的大脑、身体和遗传特征相关联。 | Korbmacher, M. | N/A | White matter microstructure links with brain, bodily and genetic attributes in adolescence, mid- and late life | |
| 一个人类化的神经元模型系统揭示了锰在神经元内吞作用、钙离子通量和线粒体生物能量学中的关键作用 | Budinger, D. | N/A | A humanized neuronal model system reveals key roles for manganese in neuronal endocytosis, calcium flux and mitochondrial bioenergetics | |
| 个体化神经生理特征的寿命演变 | da Silva Castanheira, J. | N/A | The Lifespan Evolution of Individualized Neurophysiological Traits | |
| 胰岛素抵抗、认知功能与肥胖老年人的功能性脑网络拓扑结构 | McIntyre, C. C. | N/A | Insulin resistance, cognition, and functional brain network topology in older adults with obesity | |
| 鉴定出一种源自SARS-CoV2 S1蛋白的肽段，该肽段具有类似超抗原的T细胞刺激特性。 | Tu, T. H. | N/A | The identification of a SARs-CoV2 S1 protein derived peptide with super-antigen-like stimulatory properties on T-cells | |
| 不同微气候下土壤微生物群落的比较分析 | Pall, T. | N/A | Comparative analysis of microbial communities of soils under contrasting microclimates | |
| 在妊娠早期乳腺腺泡增殖和分化的转录调控 | Garcia-Lerena, J. | N/A | Transcriptional Regulation of Mammary Alveolar Proliferation and Differentiation during Early Pregnancy | |
| 小鼠十二指肠在全身致死剂量辐射后恢复期间的转录组 | He, L. | N/A | Transcriptome of the murine duodenum during recovery after a lethal dose of total body irradiation | |
| 一个特定谱系驱动因子库将果蝇腹神经索中发育中的神经回路与行为联系起来。 | Soffers, J. H. | N/A | A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila Ventral Nerve Cord. | |
| 通过光调控激酶对内源标记蛋白进行体内调控 | vigano, a. m. | N/A | In vivo regulation of an endogenously-tagged protein by a light-regulated kinase | |
| 一种在头部固定小鼠中探索虚拟现实的环境性恐惧条件化范式。 | Krishnan, S. | N/A | A contextual fear conditioning paradigm in head-fixed mice exploring virtual reality. | |
| 分枝杆菌蛋氨酸氨肽酶1c型在30S核糖体亚基上兼职作为抗关联因子 | Banerjee, A. | N/A | Mycobacterial methionine aminopeptidase type 1c moonlights as an anti-association factor on the 30S ribosomal subunit | |
| 通过冷冻电镜结合构建和检索方法，阐明天然血小板膜中整合素αIIb3的动力学 | Han, X. | N/A | Elucidating the dynamics of Integrin αIIb3 from native platelet membranes by cryo-EM with build and retrieve method | |
| 重新布线大肠杆菌以将甲酸盐转化为甲基基团 | Mohr, M. K. F. | N/A | Rewiring Escherichia coli to Transform Formate into Methyl Groups | |
| 成功建立了基于病毒复制元件的莱茵衣藻叶绿体外源基因表达系统 | Jiang, Y. | N/A | Successful establishment of an exogenous gene expression system in Chlamydomnas chloroplast based on viral replication elements | |
| 优化的大肠杆菌亮氨酰-tRNA合成酶定向进化能够将许多非标准氨基酸加入真核生物遗传密码中，包括鸟氨酸和Nε-乙酰甲基赖氨酸。 | Ficaretta, E. D. | N/A | Optimized directed evolution of E. coli leucyl-tRNA synthetase adds many noncanonical amino acids into the eukaryotic genetic code including ornithine and Nepsilon-acetyl-methyllysine | |
| 在缺氧-缺血性脑病体外模型中，物理调控的间充质干细胞分泌组具有更高的能力来保护神经网络和翻译过程。 | Caramelo, I. | N/A | Physioxia-modulated mesenchymal stem cells secretome has higher capacity to preserve neuronal network and translation processes in hypoxic-ischemic encephalopathy in vitro model | |
| UniSPAC：一种用于连接组学中校对和注释的统一分割框架 | Deng, J. | N/A | UniSPAC: A Unified Segmentation Framework for Proofreading and Annotation in Connectomics | |
| 系统性暴露于新冠病毒样颗粒会调节活体小鼠大脑皮层神经元的放电模式。 | Das, A. | N/A | Systemic exposure to COVID-19 virus-like particles modulates firing patterns of cortical neurons in the living mouse brain | |
| 视觉-前庭整合与自我运动：人类皮层区域V6偏好向前和对齐的刺激 | Marchand, S. | N/A | Visuo-Vestibular Integration for Self-Motion: Human Cortical Area V6 Prefers Forward and Congruent Stimuli | |
| 青春期激素与青春期早期女性大脑：一项多模态脑部MRI研究 | Khetan, M. | N/A | Pubertal hormones and the early adolescent female brain: a multimodality brain MRI study | |
| 纤毛病与新生儿麻醉相互作用，导致非凋亡性胱天冬酶介导的运动功能障碍 | Saric, N. | N/A | Ciliopathy interacts with neonatal anesthesia to cause non-apoptotic caspase-mediated motor deficits | |
| 一种可编程的、无需选择的金黄色葡萄球菌CRISPR干扰系统 | Miah, R. | N/A | A programmable, selection-free CRISPR interference system in Staphylococcus aureus | |
| 鉴定并基因表征了一种新型双节冠状病毒在小熊猫中的存在 | chen, x. | N/A | Identification and genomic characterization of a novel bisegmented coronavirus in the lesser panda | |
| 对一个由宏基因组组装而成的基因组进行比较基因组分析，揭示了Mucoromycotina细根内生菌丛枝菌根真菌中独特的共生特征。 | Cole, J. | N/A | Comparative genomic analysis of a metagenome-assembled genome reveals distinctive symbiotic traits in a Mucoromycotina fine root endophyte arbuscular mycorrhizal fungus | |
| 未被探索的种子微生物群中的酵母多样性 | Marchi, M. | N/A | Unexplored Yeast diversity in Seed Microbiota | |
| 碳青霉烯类耐药高毒力肺炎克雷伯菌的分子流行病学：中国地区头孢他啶/阿维巴坦耐药的风险因素及耐药机制 | Wang, N. | N/A | Molecular epidemiology of carbapenem-resistant hypervirulent Klebsiella pneumoniae: Risk factors and resistance mechanism of ceftazidime/avibactam in China | |
| 幽门螺杆菌孤儿ATTAAT特异性甲基转移酶M.Hpy99XIX在铁代谢相关基因的协调调控中起着核心作用。 | Gottschall, W. | N/A | The Helicobacter pylori orphan ATTAAT-specific methyltransferase M.Hpy99XIX plays a central role in the coordinated regulation of genes involved in iron metabolism | |
| 弓形虫的代谢适应性与营养摄取：从摄入途径缺陷型突变体中获得的启示 | Rimple, P. A. | N/A | Metabolic Adaptability and Nutrient Scavenging in Toxoplasma gondii: Insights from Ingestion Pathway-Deficient Mutants | |
| 采用新型多重qPCR技术，在唾液中鉴定出大量aliC和aliD基因，以提高特异性，对II组非荚膜肺炎球菌进行表征。 | Laxton, C. S. | N/A | An abundance of aliC and aliD genes were identified in saliva using a novel multiplex qPCR to characterize group II non-encapsulated pneumococci with improved specificity | |
| 基于人群的元蛋白质组学揭示了肠道微生物群与表型之间的功能关联 | Liang, S. | N/A | Population-based metaproteomics reveals functional associations between gut microbiota and phenotypes | |
| 广泛存在的一类孔形成效应器扩大了沙雷氏菌VI型分泌系统的影响 | Reglinski, M. | N/A | A widely-occurring family of pore-forming effectors broadens the impact of the Serratia Type VI secretion system | |
| 2022年来自谱系2.3.4.4b的禽流感H5N1病毒比2005年来自谱系2.3.2.1的H5N1病毒在人类呼吸道上皮细胞中更好地附着和复制。 | Bauer, L. | N/A | A 2022 avian H5N1 influenza A virus from clade 2.3.4.4b attaches to and replicates better in human respiratory epithelium than a 2005 H5N1 virus from clade 2.3.2.1 | |
| 炎性间质基质细胞和IFN反应性T细胞是CHIP和MDS中人类骨髓微环境重塑的关键介质。 | Prummel, K. D. | N/A | Inflammatory Mesenchymal Stromal Cells and IFN-responsive T cells are key mediators of human bone marrow niche remodeling in CHIP and MDS | |
| 通过瞬时递送CRISPR表观基因组编辑器核糖核蛋白实现可编程的表观基因组编辑 | Nunez, J. K. | N/A | Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins | |
| 使用多重Cas12a sgRNA实现体内基因敲除并消除脱靶效应 | Port, F. | N/A | Enhanced in vivo gene knockout with undetectable off-targets using multiplexed Cas12a sgRNAs | |
| 配对CRISPR筛选以绘制顺式和反式基因调控 | Xue, X. | N/A | Paired CRISPR screens to map gene regulation in cis and trans | |
| 氨基酸酰-RNA环闭合连接的立体选择性 | Kim, S. | N/A | Stereoselectivity of Aminoacyl-RNA Loop-closing Ligation | |
| 通过促炎性S100A9和与神经退行性疾病相关的α-突触核蛋白形成异型液滴 | Veiveris, D. | N/A | Heterotypic droplet formation by pro-inflammatory S100A9 and neurodegenerative disease-related alpha-synuclein | |
| 广泛存在的肠杆菌过氧化物酶包封体的结构和生化特性 | Ubilla-Rodriguez, N. C. | N/A | Structural and biochemical characterization of a widespread enterobacterial peroxidase encapsulin | |
| 肽类凝聚体递送以在细胞内形成稳定的相互作用枢纽 | Tu, W. | N/A | Delivery of Peptide Coacervates to Form Stable Interaction Hubs In Cells | |
| 使用3T fMRI区分脑干中相邻体感核团的活动 | Howell, P. | N/A | Distinguishing the activity of adjacent somatosensory nuclei within the brainstem using 3T fMRI | |
| 紊乱的海马再激活可预测阿尔茨海默病小鼠模型中的空间记忆缺陷 | Shipley, S. | N/A | Disordered Hippocampal Reactivations Predict Spatial Memory Deficits in a Mouse Model of Alzheimer's Disease | |
| 一种用于抗生素优化的生成式人工智能方法 | Torres, M. D. T. | N/A | A generative artificial intelligence approach for antibiotic optimization | |
| PACT与ADAR1在防止自源双链RNA异常激活PKR中的协同作用 | Manjunath, L. | N/A | Cooperative Role of PACT and ADAR1 in Preventing Aberrant PKR Activation by Self-Derived Double-Stranded RNA | |
| 色氨酸饥饿对包涵体膜组成及衣原体-宿主相互作用的影响 | Riffaud-Widner, C. M. | N/A | Effect of tryptophan starvation on inclusion membrane composition and chlamydial-host interactions | |
| # BioRxiv 2024-11-26 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 量化种内性状变异和种间性状相关性对相互作用种群的影响——一种非线性平均方法 | van Benthem, K. J. | N/A | Quantifying the effects of intraspecific trait variation and interspecific trait correlations on interacting populations - a nonlinear averaging approach | |
| 通过基因拷贝数变异揭示的尼安德特人、丹尼索瓦人和智人的遗传饮食适应性 | Vicedomini, R. | N/A | Genetic dietary adaptation in Neandertal, Denisovan and Sapiens revealed by gene copy number variation | |
| 一个基于网络的水生指示物种大型溞组织学图谱 | Ngu, M. S. | N/A | A web-based histology atlas for the freshwater sentinel species Daphnia magna | |
| 腹侧视觉通路中的有机卷积可以解释V4区形状调谐的多样性 | Gold, C. S. | N/A | Organic Convolution in The Ventral Visual Pathway Can Explain the Variety of Shape Tuning in Area V4 | |
| 泛素化蛋白质组分析鉴定卡波西肉瘤疱疹病毒裂解再激活中的新宿主因子 | Causey, A. | N/A | Analysis of the ubiquitin-modified proteome identifies novel host factors in Kaposi's sarcoma herpesvirus lytic reactivation | |
| 动作电位的消亡导致神经元之间的电耦合 | Schloetter, M. | N/A | Annihilation of action potentials induces electrical coupling between neurons | |
| 海马体中相关事件的区分有助于记忆在发育过程中的再激活 | Varga, N. L. | N/A | Differentiation of related events in hippocampus supports memory reinstatement in development | |
| SARS-CoV-2感染人多能干细胞衍生的血管细胞揭示了平滑肌细胞在感染期间作为血管病理学的关键介质。 | Richards, A. | N/A | SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection | |
| 小鼠8细胞胚胎中启动了一波新的DNA甲基化，与H3K27me3共同调控印记X染色体失活。 | Yue, Y. | N/A | A wave of minor de novo DNA methylation initiates in mouse 8-cell embryos and co-regulates imprinted X- chromosome inactivation with H3K27me3 | |
| 寄生虫复杂生命周期中的多重感染 | Nguyen, P. L. | N/A | On multiple infections by parasites with complex life cycles | |
| 胶质母细胞瘤和其他颅内肿瘤会引发全身性的交感神经活动过度，从而限制了免疫治疗的效果。 | Lorrey, S. J. | N/A | Glioblastoma and other intracranial tumors elicit systemic sympathetic hyperactivity that limits immunotherapeutic responses | |
| Meteorins调节左右组织者的形成以及脊椎动物身体不对称性的建立。 | Eggeler, F. | N/A | Meteorins regulate the formation of the left-right organizer and the establishment of vertebrate body asymmetry | |
| 压应力通过侧向张力和Piezo1驱动形态发生性凋亡 | Merle, T. | N/A | Compressive stress drives morphogenetic apoptosis through lateral tension and Piezo1 | |
| RNAformer：一种简单而有效的同源性感知RNA二级结构预测模型 | Franke, J. K. H. | N/A | RNAformer: A Simple yet Effective Model for Homology-Aware RNA Secondary Structure Prediction | |
| 在隐球菌中，Shugoshin对Bub1激酶活性的依赖对于维持纺锤体组装检查点反应并非必需。 | Polisetty, S. D. | N/A | The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans | |
| 单倍体型解析的癌症核型重建与功能解析 | Brunette, G. J. | N/A | Haplotype-resolved reconstruction and functional interrogation of cancer karyotypes | |
| HSV-1感染导致+1核小体的下游移位 | Weiss, E. | N/A | HSV-1 infection induces a downstream-shift of the +1 nucleosome | |
| 利用直接RNA测序技术探究酶依赖的假尿苷酸化，以评估神经元表转录组的可塑性 | Fanari, O. | N/A | Probing enzyme-dependent pseudouridylation using direct RNA sequencing to assess neuronal epitranscriptome plasticity | |
| 机械力通过mTORC2-PKC途径调控心内膜Notch活化 | Mu, Y. | N/A | Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway | |
| 睫状蛋白IFT88的时间性消融改变了正常的脑电波模式 | Strobel, M. R. | N/A | Temporal Ablation of the Ciliary Protein IFT88 Alters Normal Brainwave Patterns | |
| 在活体中对鸟类上皮应用组织尺度的张力，以研究多尺度力学和胚层间耦合 | Oikonomou, P. | N/A | Application of tissue-scale tension to avian epithelia in vivo to study multiscale mechanics and inter-germ layer coupling | |
| 非超突变癌症通过逆转种系突变偏倚来获得驱动突变。 | Tuffaha, M. Z. | N/A | Non-hypermutator cancers access driver mutations through reversals in germline mutational bias | |
| 使用纳米孔直接RNA测序（DRS）进行mRNA psi图谱分析揭示了细胞类型特异性的假尿苷酸化 | McCormick, C. A. | N/A | mRNA psi profiling using nanopore DRS reveals cell type-specific pseudouridylation | |
| 叶绿体单线态氧信号通过植物U-Box 4介导，导致RNA全局变化，叶绿体铁螯合酶二突变体的转录组分析揭示了这一过程。 | Rai, S. | N/A | Transcript profiling of plastid ferrochelatase two mutants reveals that chloroplast singlet oxygen signals lead to global changes in RNA profiles and are mediated by Plant U-Box 4 | |
| 快速进化转变和重叠的性偏倚基因表达模式变异使得性别的简单二元分类变得困难。 | Xie, C. | N/A | Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary classification of sexes | |
| PEX14在人类细胞中作为连接optineurin和peroxisome自噬的分子桥梁。 | Li, H. | N/A | PEX14 functions as a molecular link between optineurin and pexophagy in human cells | |
| 静水流深：形态保守的多板纲动物进化中的大规模基因组重排 | Sigwart, J. D. | N/A | Still waters run deep: Large scale genome rearrangements in the evolution of morphologically conservative Polyplacophora | |
| 因果、预测还是观察？不良结局路径中关键事件关系的不同理解及其对实践的影响 | Zhou, Z. | N/A | Causal, Predictive or Observational? Different Understandings of Key Event Relationships for Adverse Outcome Pathways and Their Implications on Practice | |
| 重建自始新世以来欧亚淡水鱼类（鳅科）的系统发育和进化历史 | Slechtova, V. | N/A | Reconstructing the phylogeny and evolutionary history of freshwater fishes (Nemacheilidae) across Eurasia since early Eocene | |
| 人类微生物组来源的肽通过分子模拟影响实验性自身免疫性脑脊髓炎的发展 | Ma, X. | N/A | Human microbiome-derived peptide affects the development of experimental autoimmune encephalomyelitis via molecular mimicry | |
| 持久、私有和移动基因：进化泛基因组中基因动态模型 | Gamblin, J. | N/A | Persistent, Private and Mobile genes: a model for gene dynamics in evolving pangenomes | |
| 重塑信息格局：将Waddington景观应用于衰老信息论与表观遗传再生 | Wu, Y. | N/A | Transform the Information Landscape: Applying Waddington Landscape to Information Theory of Aging and Epigenetic Rejeuvanation | |
| 整合分子动力学模拟解析交联数据，揭示线粒体蛋白质分布 | Schuhmann, F. | N/A | Integrative Molecular Dynamics Simulations Untangle Cross-Linking Data to Unveil Mitochondrial Protein Distributions | |
| 鸟类词汇地图集：一个全球英语鸟类名称描述性类别数据库 | Morrison, E. S. | N/A | AvianLexiconAtlas: A database of descriptive categories of English-language bird names around the world | |
| 对单极刷状细胞施加逼真的苔藓纤维输入模式，会引发一系列时间响应，这些响应由不同谷氨酸受体介导的成分组成。 | Huson, V. | N/A | Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate receptors | |
| 在人类肺癌恶病质的新型临床前模型中，早期脂肪组织消耗 | Snoke, D. B. | N/A | Early adipose tissue wasting in a novel preclinical model of human lung cancer cachexia | |
| 环氧化酶-2的破坏易导致保留射血分数的心力衰竭 | Ricciotti, E. | N/A | Cyclooxygenase-2 disruption predisposes to heart failure with preserved ejection fraction | |
| 确定内在无序蛋白质在原子分辨率下的精确构象集合 | Borthakur, K. | N/A | Determining accurate conformational ensembles ofintrinsically disordered proteins at atomic resolution | |
| p62纤维的结构组织及富含钙的p62包裹脂滴货物的细胞超微结构 | Berkamp, S. | N/A | Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo | |
| 阿拉斯加红藻Devaleraea mollis和Palmaria hecatensis的培养方案 | Dittrich, M. | N/A | Cultivation protocols the rhodophytes, Devaleraea mollis and Palmaria hecatensis from Alaska | |
| 开发自主神经系统多尺度神经连接知识库 | Imam, F. T. | N/A | Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System | |
| 揭示椋鸟群集体逃逸的机制 | Papadopoulou, M. | N/A | Revealing mechanisms underlying the collective escape of starling flocks | |
| 细菌核糖体药物结合残基的自然变异 | Ekemezie, C. L. | N/A | Natural variation in the drug-binding residues of bacterial ribosomes | |
| 基因尺度体外重建揭示组蛋白乙酰化直接调控染色质结构 | Fukai, Y. | N/A | Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture | |
| 血管转录因子TMO5调控PIN1极性和器官发生，位于茎尖分生组织中MONOPTEROS的下游 | Kareem, A. | N/A | Vascular Transcription Factor TMO5 Regulates PIN1 Polarity andOrganogenesis Downstream of MONOPTEROS in the Shoot Meristem | |
| 晚更新世巴西东南部灰侏儒鹿摄食策略的千年尺度稳定性。 | Hubbe, A. | N/A | Late Quaternary millennial-scale stability of the feeding strategy of the gray brocket deer in Southeastern Brazil. | |
| 注意你的光谱：验证同位素组蛋白肽段形式鉴定时需要注意的要点 | Hijazi, H. | N/A | Mind Your Spectra: Points to be Aware of when Validating the Identification of Isobaric Histone Peptidoforms | |
| 鉴定和表征类衣原体细菌Simkania negevensis的泛素E3 RING连接酶 | Hörner, E.-M. | N/A | Identification and characterization of a ubiquitin E3 RING ligase of the Chlamydia-like bacterium Simkania negevensis | |
| 协调蛋白模块在人卵巢癌模型中单细胞分辨率下定义卡铂诱导的DNA损伤反应 | Bedia, J. S. | N/A | Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models | |
| 两种入侵性蚧虫（铁杉毛蚧和菠萝瘿蚧）的基因组使得对烟碱型乙酰胆碱受体的特征描述成为可能。 | Glendening, A. M. | N/A | Genomes of two invasive Adelges species (hemlock woolly adelgid and pineapple gall adelgid) enable characterization of nicotinic acetylcholine receptors | |
| 同时抑制COX-1和COX-2不足以引发与长期使用非甾体抗炎药相关的肠病。 | Barekat, K. | N/A | Concomitant suppression of COX-1 and COX-2 is insufficient to induce enteropathy associated with chronic NSAID use | |
| 结核分枝杆菌中一种新型放线菌特异性核糖体休眠因子 | Majumdar, S. | N/A | A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis | |
| 线粒体自噬有助于维持细胞质蛋白质稳态，以保护心脏功能 | Diwan, A. | N/A | Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function | |
| 脂肪源性间充质干细胞与视网膜色素上皮细胞在应激环境中的相互作用通过隧道纳米管进行 | Gozel, M. | N/A | Adipose-derived Mesenchymal Stem Cells and Retinal Pigment Epithelial Cells Interactions in Stress Environment via Tunneling Nanotubes | |
| 自噬抑制在低氧条件下诱导急性髓系白血病细胞死亡并增强化疗效果 | Wang, E. S. | N/A | Autophagy inhibition induces AML cell death and enhances the efficacy of chemotherapy under hypoxia | |
| S100A4和TIGIT的联合抑制通过激活T细胞和NK细胞抑制晚期乳腺癌向肺部的转移 | Leu, J.-S. | N/A | Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis to the lung by activating T and NK cells | |
| Th1细胞是富含髓系细胞的血管周围激活生态位的关键组织者。 | Bala, N. | N/A | Th1 cells are critical tissue organizers of myeloid-rich perivascular activation niches. | |
| DOA/CLK2磷酸化Fl(2)d/WTAP以增强m6A mRNA甲基转移酶复合物的活性 | McQuarrie, D. W. | N/A | DOA/CLK2 phosphorylates Fl(2)d/WTAP to enhance m6A mRNA methyltransferase complex activity | |
| 跨父系环境和遗传背景的代际遗传的胚胎特征 | Dura, M. | N/A | Embryonic Signatures of Intergenerational Inheritance across Paternal Environments and Genetic Backgrounds | |
| TonB依赖受体和氧化酶在铜抗性中的作用，该抗性与铁依赖性相关，在弯曲芽孢杆菌中 | Cherry, P. | N/A | Role of a TonB-dependent receptor and an oxygenase in iron-dependent copper resistance in Caulobacter crescentus | |
| 通过片段重复实现的可进化性遵循物种特异性动力学 | Islam, S. | N/A | Evolvability through segmental duplication follows species-specific dynamics | |
| 通过转录激活在哺乳动物生殖细胞中启动基因启动子处的表观遗传景观 | Li, P. | N/A | Priming Epigenetic Landscape at Gene Promoters through Transcriptional Activation in Mammalian Germ Cells | |
| 逐步破坏大肠杆菌RNA聚合酶-{lambda}R启动子接触和转录起始中的气泡塌陷的证据 | Rector, M. J. | N/A | Evidence for Stepwise Disruption of E. coli RNA Polymerase-{lambda}R Promoter Contacts and Bubble Collapse in Transcription Initiation | |
| 使用RAG的大型语言模型在自动标注表型描述方面的有效性 | Kainer, D. | N/A | The effectiveness of Large Language Models with RAG for auto-annotating phenotype descriptions | |
| 临床实践中的生物信息学建议 | Lavrichenko, K. | N/A | Recommendations for Bioinformatics in Clinical Practice | |
| CHARMER：检测和协调跨组织和Hi-C协议的高置信度染色质相互作用 | Cole, S. | N/A | CHARMER: detecting and harmonizing high-confidence chromatin interactions across tissues and Hi-C protocols | |
| Sirt5通过抑制ANT2的乳酸化来保护心脏功能免受缺血-再灌注损伤。 | Zhang, L. | N/A | Sirt5 preserves cardiac function in ischemia-reperfusion injury by inhibiting ANT2 lactylation | |
| 腿部固定及随后的恢复期抗阻训练对年轻健康成年人骨骼肌血管生成相关标志物的影响，与先前的抗阻训练经验无关。 | McIntosh, M. C. | N/A | Leg immobilization and subsequent recovery resistance training affect skeletal muscle angiogenesis related markers in young healthy adults regardless of prior resistance training experience | |
| 弥合巴西生物科学家Python培训差距：改进与挑战 | Crestana, G. S. | N/A | Bridging the Python Training Gap for Bioscientists in Brazil: Improvements and Challenges | |
| 单脉冲电刺激人脑的细胞类型特异性反应 | Cowan, R. L. | N/A | Cell-type specific responses to single-pulse electrical stimulation of the human brain | |
| 离线5Hz-rTUS诱发皮层脊髓兴奋性双盲重复实验失败 | Fong, P.-Y. | N/A | Failed Double-Blind Replication of Offline 5Hz-rTUS-Induced Corticospinal Excitability | |
| 通过静息脑熵（BEN）揭示了鼻内催产素给药的年龄依赖性效应。 | Song, D. | N/A | Age-dependent effects of intranasal oxytocin administration were revealed by resting brain entropy (BEN) | |
| 铜绿假单胞菌介导的心脏功能障碍是由感染期间释放的胞外囊泡驱动的。 | Rajaram, M. V. S. | N/A | Pseudomonas aeruginosa-mediated cardiac dysfunction is driven by extracellular vesicles released during infection | |
| 聚磷酸盐积累的贝氏硫细菌垫的非凡生理特征表明，磷酸盐缓冲在海洋沉积物中起着关键作用。 | Iakovchuk, N. | N/A | Extraordinary physiology of polyphosphate-accumulating Beggiatoa mats suggests a key role for phosphate buffering in marine sediments | |
| 组蛋白伴侣Spt6通过其保守的N端结构域控制染色质结构 | Warner, J. L. | N/A | The histone chaperone Spt6 controls chromatin structure through its conserved N-terminal domain | |
| 一个用于绘制生物多样性、气候和可持续发展关键生命支持区（ELSAs）的操作框架 | Venter, O. | N/A | An operational framework to map Essential Life Support Areas (ELSAs) for biodiversity, climate, and sustainable development | |
| 使用总蛋白方法对保留和降低射血分数的心力衰竭患者进行AI驱动的分类 | Lenzi, A. | N/A | AI-driven Classification of Heart Failure Preserved and Reduced Ejection Fraction Patients Using the Total Protein Approach | |
| Bwa，一种碱性神经酰胺酶-ACER2的直系同源物，通过促炎细胞因子信号传导促进果蝇肠道干细胞增殖。 | Rahman, M. M. | N/A | Bwa, an ortholog of alkaline ceramidase-ACER2, promotes intestinal stem cell proliferation through pro-inflammatory cytokine signaling in Drosophila melanogaster | |
| 肾足细胞的线粒体呼吸能力较高，且随年龄变化，并具有性别二态性。 | Campbell, M. D. | N/A | Mitochondrial respiratory capacity in kidney podocytes is high, age-dependent, and sexually dimorphic. | |
| 探讨癌症患者对微生物组工程技术态度的研究 | Owen, K. A. | N/A | Engaging cancer patients on their attitudes towards microbiome engineering technologies | |
| 侧化的记忆网络解释了昆虫导航中使用的高阶视觉特征 | Filippi, G. | N/A | Lateralised memory networks explain the use of higher-order visual features in navigating insects | |
| 增强的Notch依赖性胶质生成和延迟的生理成熟是Lowe综合征中神经发育缺陷的基础 | Sharma, Y. | N/A | Enhanced Notch dependent gliogenesis and delayed physiological maturation underlie neurodevelopmental defects in Lowe syndrome | |
| 细胞和髓鞘构筑图谱指导下的灰质和白质结构特性的耦合老化 | Hoagey, D. A. | N/A | Coupled aging of cyto- and myeloarchitectonic atlas-informed gray and white matter structural properties | |
| 跨参考框架的多感官整合与加法前馈网络 | Farahmandi, A. | N/A | Multisensory integration across reference frames with additive feed-forward networks | |
| 在狼疮性肾炎中，纤维化区域的炎症先于肾功能的丧失。 | Malvica, S. | N/A | Inflammation in Areas of Fibrosis Precedes Loss of Kidney Function in Lupus Nephritis | |
| 欧洲受保护地区面临气候变化的加速暴露 | Cimatti, M. | N/A | The accelerating exposure of European protected areas to climate change | |
| 婴儿代谢的动态全身模型 | Zaunseder, E. | N/A | Dynamic whole-body models for infant metabolism | |
| 有额颞叶痴呆家族史的无症状个体尿液蛋白质的变化 | Su, Y. | N/A | Changes in urinary proteins of unaffected individuals with a family history of frontotemporal dementia | |
| 谱系特异性性状变异导致入侵性多宿主野生动物寄生虫中广泛存在同时共存和竞争排斥动态 | Garner, T. W. | N/A | Lineage-specific trait variation generates widespread, contemporaneous coexistence and competitive exclusion dynamics in an invasive, multihost wildlife parasite | |
| 汉密尔顿法则的一般版本 | van Veelen, M. | N/A | The general version of Hamilton's rule | |
| 使用边缘计算的玻璃体视网膜手术术中增强现实 | Ye, R. Z. | N/A | Intraoperative Augmented Reality for Vitreoretinal Surgery using Edge Computing | |
| 通过ROCK抑制在蛋白酶可降解水凝胶中促进人唾液腺干细胞/祖细胞的极化和分化 | Metkari, A. | N/A | Promoting Polarization and Differentiation of Primary Human Salivary Gland Stem/Progenitor Cells in Protease-Degradable Hydrogels via ROCK Inhibition | |
| iSIM-sigma：分子相似性高效标准差计算 | Perez, K. L. | N/A | iSIM-sigma: efficient standard deviation calculation for molecular similarity | |
| SPACE：STRING蛋白质作为互补嵌入 | Hu, D. | N/A | SPACE: STRING proteins as complementary embeddings | |
| DockFormer：利用成对Transformer高效预测多模态受体-配体相互作用 | Shor, B. | N/A | DockFormer: Efficient Multi-Modal Receptor-Ligand Interaction Prediction using Pair Transformer | |
| 利用独特性：在弹性奠基图上的种子-链-延伸对齐 | Rizzo, N. | N/A | Exploiting uniqueness: seed-chain-extend alignment on elastic founder graphs | |
| DyNDG：基于时间序列动态网络整合差异基因识别白血病相关基因 | A, J. | N/A | DyNDG: Identifying Leukemia-Related Genes based on the Time-Series Dynamical Network by Integrating Differential Genes | |
| LRRC8A:D体积调节阴离子通道的组装与脂质调控 | Lurie, A. | N/A | Assembly and lipid-gating of LRRC8A:D volume-regulated anion channels | |
| 利用实验血管数据进行高分辨率脑肿瘤模拟 | Behle, E. | N/A | Leveraging Experimental Vasculature Data for High Resolution Brain Tumor Simulations | |
| 黑色素瘤患者前哨淋巴结中的免疫组织对远处转移具有预后意义 | Amitay, Y. | N/A | Immune organization in sentinel lymph nodes of melanoma patients is prognostic of distant metastases | |
| 重复给予药用级中链甘油三酯（一种常见的药理学辅料），通过腹腔注射而非口服途径在小鼠中表现出剂量依赖性毒性。 | Adler-Wachter, M. | N/A | Repeated administration of pharmaceutical-grade medium chain triglycerides, a common pharmacologic excipient, confers dose-dependent toxicity by the intraperitoneal but not oral route in mice | |
| 识别新型药物相互作用：迈向女性生殖健康精准医学 | Garcia-Acero, P. | N/A | Identification of novel drug-drug interactions: towards precision medicine in women's reproductive health | |
| 比较转录组学分析揭示了由Pantoea agglomerans pv. betae的III型效应子操控的候选基因，这些基因导致了甜菜根瘤的形成。 | Gupta, P. | N/A | Comparative transcriptomic profile reveals candidate genes manipulated by type III effectors of Pantoea agglomerans pv. betae leading to gall formation in beet | |
| 蒸腾作用洞察：通过高级建模估算蒸腾作用 | Friedman, S. | N/A | Transpiration Insights: Estimating Transpiration Through Advanced Modeling | |
| 评估法国本土人口暴露于农药施用的程度，采用高分辨率的农药使用强度地图 | Nowak, B. | N/A | Assessment of population exposure to pesticide applications with a high-resolution map of pesticide use intensity for mainland France | |
| cpTatC蛋白的N端结构域与叶绿体TAT转运中的前体成熟结构域相互作用 | Maddethalawe, T. | N/A | The N-terminal Domain of cpTatC Protein Interacts with the Precursor Mature Domain in Chloroplast TAT Translocation | |
| 海洋硅藻三角褐指藻（Phaeodactylum tricornutum）对生长素（auxin）的生理、转录组和代谢组响应 | Chen, Y.-T. | N/A | Physiological, transcriptomic and metabolomic responses of the marine diatom Phaeodactylum tricornutum to auxin | |
| 完整的菠菜叶绿体中类囊体膜的分子结构 | Wietrzynski, W. | N/A | Molecular architecture of thylakoid membranes within intact spinach chloroplasts | |
| OsbHLH089和OsbHLH094通过调节OsSLR1水平来维持水稻的雄性生殖适应性 | Fernandes, T. | N/A | OsbHLH089 and OsbHLH094 Modulate OsSLR1 Levels to Maintain Male Reproductive Fitness in Rice | |
| 使用Microsoft Sway作为药剂学实验课程中生成数据的存储库：一项关于外用制剂特性表征的案例研究 | Chen, Q. | N/A | Employing Microsoft Sway as a Repository for Data Generated in Pharmaceutics Experimental Courses: A Case study on Topical Formulation Characterization | |
| 预处理脂肪间充质干细胞衍生的外泌体对贝赫切特葡萄膜炎免疫调节的影响 | Gozel, M. | N/A | Effects of Primed Adipose Mesenchymal Stem Cell-Derived Exosomes on Immunomodulation in Behcet Uveitis | |
| 在人类细胞中表达重组人谷氨酰化TTLLs会导致不同的微管谷氨酰化模式，其中只有TTLL6会破坏微管动力学。 | Al Kabbani, M. A. | N/A | Expression of recombinant human glutamylating TTLLs in human cells leads to differential tubulin glutamylation patterns, with only TTLL6 disrupting microtubule dynamics | |
| 使用新型造影剂对髓核进行高分辨率三维显微CT成像 | Buckles, M. M. | N/A | High-resolution 3-dimensional micro-CT imaging of the nucleus pulposus using a novel contrast agent | |
| 亚热带树木生物多样性实验中，物种内和个体内的性状变异性随树种丰富度的增加而降低。 | Castro Sanchez-Bermejo, P. | N/A | Intraspecific and intraindividual trait variability decrease with tree species richness in a subtropical tree biodiversity experiment | |
| 沿海盐沼滨螺Littoraria irrorata的生态关联：现场和实验室证据表明其对植被栖息地的偏好 | Klinges, D. H. | N/A | Ecological associations of the coastal marsh periwinkle snail Littoraria irrorata: field and laboratory evidence of vegetation habitat preferences | |
| 多物种生态动力学中结构化与随机相互作用的相互作用 | Giral Martinez, J. | N/A | Interplay of structured and random interactions in many-species ecological dynamics | |
| 海拔和海洋屏障塑造了新西兰卡波卡波瓦伊（Uropetala）蜻蜓的分布、扩散和多样性 | Tolman, E. R. | N/A | Elevational and Oceanic Barriers Shape the Distribution, Dispersal and Diversity of Aotearoa's Kapokapowai (Uropetala) Dragonflies | |
| 解锁两栖植物适应的秘密：RNA修饰的作用 | Mazdziarz, M. A. | N/A | Unlocking the Secrets of Amphibious Plant Adaptation: The Role of RNA Modifications | |
| 真菌GPCR基因家族的鉴定与分类 | LIU, Z. | N/A | Identification and Classification of Fungal GPCR Gene Families | |
| 基因组语言模型的局限性与增强：动态选择方法 | Qiu, S. | N/A | Limitations and Enhancements in Genomic Language Models: Dynamic Selection Approach | |
| 氯化物遗传编码指示剂的定向进化 | Peng, W. | N/A | Directed Evolution of a Genetically Encoded Indicator for Chloride | |
| 脂肪组织的机械各向异性调节卵巢癌的侵袭 | Gonzalez-Molina, J. | N/A | The mechanical anisotropy of adipose tissues regulates ovarian cancer invasion | |
| 基于强化学习的电机脑机接口软件模拟器 | Liang, K.-F. | N/A | A reinforcement learning based software simulator for motor brain-computer interfaces | |
| VaxLLM：利用微调的大型语言模型进行布鲁氏菌疫苗的自动化标注 | Li, X. | N/A | VaxLLM: Leveraging Fine-tuned Large Language Model for automated annotation of Brucella Vaccines | |
| 利用人类泛蛋白组提升蛋白质组学和元蛋白质组学中的肽段和蛋白质鉴定能力 | Canderan, J. | N/A | Leveraging the Human Panproteome to Enhance Peptide and Protein Identification in Proteomics and Metaproteomics | |
| 通过计算机模拟发现大肠杆菌中芳香族氨基酸生产的靶点 | Fonseca, A. P. | N/A | In silico target discovery for aromatic amino acid production in Escherichia coli | |
| OrthologAL：一个用于非人类临床前高维基因表达数据质量感知人源化的Shiny应用程序 | CHOWDARY, R. | N/A | OrthologAL: A Shiny application for quality-aware humanization of non-human pre-clinical high-dimensional gene expression data | |
| 使用二甲双胍针对更年期过渡期可改善乳腺癌预后，但停药对代谢健康有不利影响：来自绝经后乳腺癌的临床前模型研究结果。 | Corleto, K. A. | N/A | Targeting the menopause transition with metformin improves breast cancer outcomes, but discontinuation has deleterious effects on metabolic health: Findings from a preclinical model of postmenopausal breast cancer. | |
| 在癌症中，CD47相对于CD24在巨噬细胞免疫检查点中占主导地位。 | Allen, J. | N/A | CD47 predominates over CD24 as a macrophage immune checkpoint in cancer. | |
| 逐步组装冠爬行动物解剖结构：晚古生代新双孔类旁系群阐明 | Jenkins, X. | N/A | Stepwise Assembly Of Crown Reptile Anatomy Clarified By Late Paleozoic Outgroups Of Neodiapsida | |
| 内皮细胞中的RIPK3可减轻缺血-再灌注损伤中的器官特异性炎症和血管通透性 | Johnson, C. F. | N/A | Endothelial RIPK3 minimizes organotypic inflammation and vascular permeability in ischemia-reperfusion injury | |
| 植物易感性的组织非依赖性：通过根和叶对系统性植物病原菌拉氏假单胞菌在茄子和番茄幼苗中的比较致病性研究 | Bhuyan, S. | N/A | Tissue-independent nature of plant susceptibility: a comparative pathogenicity study of the systemic phytopathogen Ralstonia pseudosolanacearum in eggplant and tomato seedlings through root and leaf | |
| 一种基于质量源于设计（QbD）的策略，用于开发同时负载姜黄素和siRNA的脂质体复合物，以对抗与骨关节炎相关的炎症和氧化应激。 | Ranamalla, S. R. | N/A | A QbD strategy to develop curcumin and siRNA co-loaded lipoplexes to combat osteoarthritis-related inflammation and oxidative stress | |
| 溶酶体钙信号通过钙刺激的腺苷酸环化酶1和8介导急性α-肾上腺素能反应 | Akerman, E. | N/A | Lysosomal calcium signalling contributes to the acute α-adrenergic response via calcium-stimulated adenylyl cyclase 1 and 8 | |
| 心房心肌细胞中的心房颗粒作为酸性钙储存库 | Akerman, E. | N/A | Atrial Granules in Atrial Cardiomyocytes as Acidic Calcium Stores | |
| 鉴定调控启动子序列在蒺藜苜蓿（Medicago truncatula）根瘤衰老初期指导MtCP6转录的作用。 | Yang, L. | N/A | Identification of regulatory promoter sequences directing MtCP6 transcription at the onset of nodule senescence in Medicago truncatula. | |
| 人工智能对蛋白质结构的建模能否区分传感器和辅助NLR免疫受体？ | Toghani, A. | N/A | Can AI modelling of protein structures distinguish between sensor and helper NLR immune receptors? | |
| 单细胞代谢振荡普遍存在，可能有助于缓解蛋白质组约束。 | Wongprommoon, A. | N/A | Single-cell metabolic oscillations are pervasive and may alleviate a proteome constraint | |
| 额极皮层刺激导致反事实加工的长期中断：来自局部场电位变化的见解 | Ainsworth, M. | N/A | Frontopolar cortex stimulation induces prolonged disruption to counterfactual processing: insights from altered local field potentials | |
| 阅读习得促使语言跨模态在左腹侧枕颞皮层中的融合 | Debska, A. | N/A | Reading Acquisition Drives Linguistic Cross-Modal Convergence in The Left Ventral Occipitotemporal Cortex | |
| 在成年早产小鼠的感觉皮层和前额叶皮层中，对行为显著线索的类似青少年的处理方式 | McCoy, E. | N/A | Adolescent-like Processing of Behaviorally Salient Cues in Sensory and Prefrontal Cortices of Adult Preterm-Born Mice | |
| 人类视觉皮层中概念流形的几何结构变异 | St-Yves, G. | N/A | Variation in the geometry of concept manifolds acrosshuman visual cortex | |
| CalliCog：一个用于自由行为非人灵长类的开源认知神经科学工具包 | Scott, J. | N/A | CalliCog: an open-source cognitive neuroscience toolkit for freely behaving nonhuman primates | |
| 量化存储在突触连接中的信息，而非神经网络的放电模式 | Fan, X. | N/A | Quantifying information stored in synaptic connections rather than in firing patterns of neural networks | |
| 通过内部感觉预测的持续学习，建模对改变的感觉反馈的语音适应 | Elie, B. | N/A | Modeling speech adaptation to altered sensory feedback through continuous learning of internal sensory predictions | |
| 气质特质的神经行为相关性：基于气质与性格量表及功能性磁共振成像选择任务的见解 | Abbasi Sisara, M. | N/A | Behavioral and Neural Correlates of Temperament Traits: Insights from Temperament and Character Inventory and fMRI-Based Choice Tasks | |
| 塑造发育中的小人：感觉重映射中剥夺与补偿行为的作用 | Tucciarelli, R. | N/A | Shaping the developing homunculus: the roles of deprivation and compensatory behaviour in sensory remapping | |
| 皮层组装体支持快速放电的人类PVALB+皮层中间神经元的发育，并揭示了与精神分裂症相关的缺陷。 | Walsh, R. M. | N/A | Cortical assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects | |
| 元认知内省改变了决策前神经证据积累的动力学 | Dou, W. | N/A | Metacognitive Introspection Alters the Dynamics of Pre-Decisional Neural Evidence Accumulation | |
| 在自然视觉中，观察到的动作的行为相关特征在皮层表征的几何结构中占据主导地位。 | Han, J. | N/A | Behaviorally-relevant features of observed actions dominate cortical representational geometry in natural vision | |
| 成人嗅球解剖、组织学及超微结构：血管及淀粉样小体评估 | Raspeno-Garcia, J. | N/A | Anatomy, histology and ultrastructure of the adult human olfactory peduncle: blood vessel and corpora amylacea assessment | |
| 你的记忆宫殿有多坚固？可靠的房间表征预示着随后放置物品的恢复 | Masis-Obando, R. | N/A | How sturdy is your memory palace? Reliable room representations predict subsequent reinstatement of placed objects | |
| 神经遗传学证据表明，Lgr3阳性生长控制中间神经元在果蝇中表现出振荡行为 | Zanini, R. | N/A | Neurogenetic evidence for oscillatory behavior of Lgr3-positive growth control interneurons in Drosophila | |
| 跨感觉切换的神经机制：延迟感觉处理和增加认知努力的证据 | Vanneau, T. | N/A | Neural Mechanisms of Intersensory Switching: Evidence for Delayed Sensory Processing and Increased Cognitive Effort | |
| 在个体水平的功能梯度分析中，普罗克鲁斯特斯对齐法 | Sasse, L. | N/A | Procrustes Alignment in Individual-level Analyses of Functional Gradients | |
| 纵向结构磁共振脑影像配准刚体配准算法比较研究 | Rezaee Jouryabi, Y. | N/A | A comparative study of rigid-body registration algorithms for the alignment of longitudinal structural MRI of the brain | |
| APP NL-G-F小鼠内侧内嗅皮层中的空间编码受损和神经元过度活跃 | Rodriguez, G. A. | N/A | Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of APP NL-G-F mice | |
| 嗜酸性粒细胞促进单核细胞向巨噬细胞分化及抗菌免疫 | Wilson, G. J. | N/A | Eosinophils promote monocyte to macrophage differentiation and anti-bacterial immunity | |
| 中性粒细胞趋化因子CXCL5在急性肺损伤中诱导肺屏障通透性 | Berger, S. | N/A | Neutrophil-chemoattractant CXCL5 induces lung barrier permeability in acute lung injury | |
| 增强的艰难梭菌TcdB疫苗与合成双TLR配体佐剂联合使用的免疫原性。 | Naz, F. | N/A | Enhanced immunogenicity of a Clostridioides difficile TcdB vaccine adjuvanted with a synthetic dual-TLR ligand adjuvant. | |
| MCUB依赖性抑制线粒体钙摄取的机制 | Rai, N. K. | N/A | Mechanism of MCUB-dependent inhibition of mitochondrial calcium uptake | |
| 环节动物视角下FGF信号在尾部再生中的作用 | Shalaeva, A. Y. | N/A | Annelid perspectives into the role of FGF signaling in caudal regeneration | |
| 整合体复合物通过全局调控转录延伸，防止神经元过早分化。 | Somsen, H. B. | N/A | The Integrator complex prevents premature neuronal differentiation through global control of transcription elongation. | |
| 性染色体塑造了植入前小鼠胚胎的转录景观 | Snell, D. M. | N/A | Sex chromosomes shape the transcriptional landscape of the preimplantation mouseembryo | |
| 尽管与膜翅目昆虫存在进化上的相似性，但从蟑螂到白蚁的社会性进化过程中，监管复杂性有所降低。 | Jones, A. | N/A | Reduced regulatory complexity associated with the evolutionary transition to sociality from cockroaches to termites despite evolutionary parallels with Hymenoptera | |
| 翻译上游区域的快速降解表明翻译起始过程效率低下。 | Tress, M. L. | N/A | The rapid degradation of translated upstream regions points to an inefficient translation initiation process | |
| 颜色变化作为免疫能力权衡假说预测的权衡的替代解决方案 | Sacchi, R. | N/A | Colour morphs as alternative solutions to the trade-off predicted by the Immuno-Competence Handicap Hypothesis | |
| 秀丽隐杆线虫可靠的气味感知与可变的联想学习 | Tasnim, S. | N/A | Reliable odorant sensing but variable associative learning in C. elegans | |
| 量子关联在工程化磁敏荧光蛋白中的应用使活细胞内实现多模态传感成为可能 | Abrahams, G. J. | N/A | Quantum Correlations in Engineered Magneto-Sensitive Fluorescent Proteins Enables Multi-Modal Sensing in Living Cells | |
| 从头组装的数据库使得无需事先了解群落组成，即可对微生物群进行基于物种特异性蛋白质的稳定同位素探针研究。 | Klaes, S. | N/A | De novo assembled databases enable species-specific protein-based stable isotope probing of microbiomes without prior knowledge of the community composition | |
| 深度学习揭示了对抗肺炎克雷伯菌的潜在抗生素耐药药物 | Lin, P. | N/A | Deep Learning Unravels Potential Antibiotic-Resistance Drugs against Klebsiella Pneumoniae | |
| 易患炎症性肠病会促进小鼠模型中ATF6驱动的结肠癌发生侵袭性癌变。 | Kövilein, J. | N/A | Susceptibility to inflammatory bowel diseases promotes invasive carcinomas in a murine model of ATF6-driven colon cancer | |
| 利用机器学习识别特发性肺纤维化与肺鳞状细胞癌之间分子网络的差异 | Nojima, Y. | N/A | Identification of the differences in molecular networks between idiopathic pulmonaryfibrosis and lung squamous cell carcinoma using machine learning | |
| 皮质神经活动在应对机械性扰动时的反应：手偏好和使用手的影响 | Hooks, K. | N/A | Cortical neural activity during responses to mechanical perturbation: Effects of hand preference and hand used | |
| 在慢性暴饮酒精后的戒断和长期戒断期间，小胶质细胞促进神经退行性和过度兴奋。 | McNair, E. | N/A | Microglia promote neurodegeneration and hyperkatifeia during withdrawal and prolonged abstinence from chronic binge alcohol | |
| 一种用于θ节律采样的通用过程，可以对环境信息或内部存储信息进行采样。 | Fiebelkorn, I. C. | N/A | A domain-general process for theta-rhythmic sampling of either environmental information or internally stored information | |
| 眶额皮层和前扣带皮层亚区在决策与脑-体调节中的功能二分法 | Papageorgiou, G. K. | N/A | Functional Dichotomy of Orbitofrontal Cortex and Anterior Cingulate Cortex Subregions in Decision-Making and Brain-Body Regulation | |
| 处理双关幽默中的负面词汇：混合情感的动态表现，融合了娱乐性与消极性 | Sun, Y. | N/A | Processing negative words in pun-humor: dynamic representation of mixed feelings blending amusement and negativity | |
| 通过PARG99选择性抑制细胞质中的PARylation：一种针对FUS相关神经退行性变的靶向方法 | Kodavati, M. | N/A | Selective Inhibition of Cytosolic PARylation via PARG99: A Targeted Approach for Mitigating FUS-associated Neurodegeneration | |
| 通过体内邻近标记技术揭示视网膜神经元中的电突触蛋白质组 | Tetenborg, S. | N/A | Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling | |
| 学习和可塑性信号诱导突触线粒体中的极化ATP合酶 | Hu, Y. | N/A | Polarized ATP synthase in synaptic mitochondria induced by learning and plasticity signals | |
| 耳念珠菌氧化应激反应相关过氧化物酶Tsa1b作为一种毒力因子，促进感染。 | Areitio, M. | N/A | The oxidative stress response-related peroxiredoxin Tsa1b of Candida auris functions as a virulence factor that promotes infection | |
| 鉴定出EcpK，一种对粘细菌Myxococcus xanthus中胞外多糖生物合成至关重要的细菌酪氨酸假激酶 | Bloecher, L. | N/A | Identification of EcpK, a bacterial tyrosine pseudokinase important for exopolysaccharide biosynthesis in Myxococcus xanthus | |
| 多个冗余的羧酸转运蛋白支持恶性疟原虫线粒体代谢 | Prigge, S. T. | N/A | MULTIPLE, REDUNDANT CARBOXYLIC ACID TRANSPORTERS SUPPORT MITOCHONDRIAL METABOLISM IN PLASMODIUM FALCIPARUM | |
| 当代H3N2病毒受体结合域中的上位性，这些病毒已回复为结合唾液酸化二乳糖胺重复序列 | Liang, R. | N/A | Epistasis in the receptor binding domain of contemporary H3N2 viruses that reverted to bind sialylated diLacNAc repeats | |
| 细菌RNA中假尿苷的定量图谱 | Sharma, S. | N/A | Quantitative mapping of pseudouridines in bacteria RNA | |
| MdfA和ClpCP介导的发育调控蛋白水解在枯草芽孢杆菌孢子形成过程中的代谢分化中起作用 | Riley, E. P. | N/A | Developmentally-regulated proteolysis by MdfA and ClpCP mediates metabolic differentiation during Bacillus subtilis sporulation | |
| 肠球菌细胞壁的重塑通过释放肠球菌多糖抗原（EPA）来支撑其致病性。 | Smith, R. E. | N/A | Enterococcal cell wall remodelling underpins pathogenesis via the release of the Enteroccocal Polysaccharide Antigen (EPA) | |
| 生长速率调控酿酒酵母中RNA聚合酶II的转录延伸 | Garrido-Godino, A. I. | N/A | Growth rate regulates RNA polymerase II transcription elongation in Saccharomyces cerevisiae | |
| COVID-19疾病严重程度与T细胞受体库之间的关联 | Chen, X. | N/A | Association between COVID-19 Disease Severity and T Cell Receptor Repertoire | |
| 编程群体组成和多细胞形态的综合比率计算 | An, B. | N/A | Synthetic ratio computation for programming population composition and multicellular morphology | |
| 高分辨率分析揭示了转基因的转录和翻译调控的耦合机制。 | Peterman, E. L. | N/A | High-resolution profiling reveals coupled transcriptional and translational regulation of transgenes | |
| 基于大肠杆菌的无细胞系统中苹果酸的碳节约型生物生产 | Cardiff, R. | N/A | Carbon-conserving Bioproduction of Malate in an E. coli-based Cell-Free System | |
| 在日本发现异源四倍体杂种物种黑曲霉 | Shibata, S. | N/A | Discovery of allodiploid hybrid species Aspergillus latus in Japan | |
| 罗非鱼湖病毒核蛋白与RNA结合的结构 | Arragain, B. | N/A | Structure of the Tilapia lake virus nucleoprotein bound to RNA | |
| 果糖诱发代谢功能障碍的倾向取决于基线饮食、饮食暴露的时间长度以及小鼠的性别。 | Fadhul, T. | N/A | The propensity of fructose to induce metabolic dysfunction is dependent on the baseline diet, length of the dietary exposure, and sex of the mice. | |
| 拟南芥PRMT5通过缓冲供体剪接位点的遗传变异，调节前体mRNA剪接和发育 | Beckel, M. S. | N/A | Arabidopsis PRMT5 Buffers Pre-mRNA Splicing and Development Against Genetic Variation in Donor Splice Sites | |
| 从700,000生物银行参与者中探究DNA重复扩展的原因和后果 | Hujoel, M. L. A. | N/A | Insights into the causes and consequences of DNA repeat expansions from 700,000 biobank participants | |
| 启动子与关键的压力相关转录因子结合，以调控压力应答基因簇。 | Malfait, J. | N/A | Epromoters bind key stress-related transcription factors to regulate clusters of stress response genes | |
| # BioRxiv 2024-11-25 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 解决方案结构和突触分析揭示了双特异性T细胞衔接子效力的决定因素 | Leithner, A. | N/A | Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency | |
| 解构富营养化与自然变异对法国沿海潟湖大型底栖生物群落的影响 | Jones, A. G. | N/A | Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons | |
| 患者差异对肾素-血管紧张素系统影响的数学建模及其在COVID-19肺纤维化结果中的应用 | Islam, M. A. | N/A | Mathematical Modeling of Impacts of Patient Differences on Renin-Angiotensin System and Applications to COVID-19 Lung Fibrosis Outcomes | |
| 在转基因烟草植物从烟草蚀纹病毒感染中恢复期间，胼胝质在胞间连丝处的沉积表明其在病毒移动限制中起作用。 | Vargas-Mejia, P. | N/A | Callose deposition at plasmodesmata suggests a role in viral movement restriction in transgenic tobacco plants during recovery from Tobacco etch virus infection | |
| 轻度多动症有益吗？在整个人口中，大脑的临界性在多动症症状评分处于中间水平时达到峰值。 | Haque, H. | N/A | Is mild ADHD beneficial? Brain criticality peaks at intermediate ADHD symptom scores across the population | |
| 复杂性状遗传学中建模上下文依赖性的权衡 | Weine, E. | N/A | Tradeoffs in Modeling Context Dependency in Complex Trait Genetics | |
| 多巴胺能神经元中食欲素受体1型缺乏增加新奇诱导的 locomotion 和探索 | Xiao, X. | N/A | Deficiency of Orexin Receptor Type 1 in Dopaminergic Neurons Increases Novelty-Induced Locomotion and Exploration | |
| 肿瘤相关巨噬细胞的抗原呈递促使肿瘤浸润T细胞从原初耗竭状态转变为终末耗竭状态。 | Waibl Polania, J. | N/A | Antigen presentation by tumor-associated macrophages drives tumor-infiltrating T cells from a progenitor exhaustion state to terminal exhaustion | |
| bamSliceR：一个用于快速跨队列变异分析的Bioconductor包 | Huang, Y. P. | N/A | bamSliceR: a Bioconductor package for rapid, cross-cohort variant analysis | |
| 贴纸-间隔物能量的分离控制了亚稳态凝聚物的聚结 | Chattaraj, A. | N/A | Separation of sticker-spacer energetics governs the coalescence of metastable condensates | |
| 肝窦内皮细胞构成了血红蛋白清除的主要途径。 | Zurawska, G. | N/A | Liver sinusoidal endothelial cells constitute a major route for hemoglobin clearance | |
| 解析NAP-CNB机器学习增强型肿瘤新抗原预测的力量 | Mendez-Perez, A. | N/A | Unraveling the Power of NAP-CNB's Machine Learning-enhanced Tumor Neoantigen Prediction | |
| 研究地钱（Marchantia polymorpha）中的顶端切口、顶端优势及分生组织再生的现象。 | Marron, A. O. | N/A | Investigating the apical notch, apical dominance and meristem re-emergence in Marchantia polymorpha. | |
| ELF3-BBX24/BBX25-PIF4模块控制拟南芥的热感应生长 | Malakar, B. C. | N/A | The ELF3-BBX24/BBX25-PIF4 module controls thermosensory growth in Arabidopsis | |
| 时间注意在中间处理阶段增强了前扣带回皮层的刺激信息 | Zhu, J. | N/A | Temporal attention amplifies stimulus information in fronto-cingulate cortex at an intermediate processing stage | |
| 投射至腹侧CA1区的内梨状神经元是识别记忆的关键节点。 | Yamawaki, N. | N/A | Endopiriform neurons projecting to ventral CA1 are a critical node for recognition memory | |
| 自噬蛋白ATG14通过防止非计划性的细胞焦亡激活，从而在早期妊娠期间保障胚胎运输。 | POPLI, P. | N/A | The autophagy protein, ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy | |
| 开发无细胞平台以发现、表征和工程化翻译后修饰 | Wong, D. A. | N/A | Development of cell-free platforms for discovering, characterizing, and engineering post-translational modifications | |
| 呼吸暂停突显了小鼠的睡眠结构 | Casali, G. | N/A | Respiratory pauses highlight sleep architecture in mice | |
| 通过物种相互作用在生物多样性实验中划分生态系统生产力的变化 | Tao, J. | N/A | Partitioning changes in ecosystem productivity by effects of species interactions in biodiversity experiments | |
| ROS诱导的压力促进抗生素抗性在传统活性污泥工艺中的富集和出现 | Manna, B. | N/A | ROS-Induced Stress Promotes Enrichment and Emergence of Antibiotic Resistance in Conventional Activated Sludge Processes | |
| RuBisCO的进化动力学：小亚基的出现及其随时间的演变影响 | Amritkar, K. | N/A | Evolutionary Dynamics of RuBisCO: Emergence of the Small Subunit and its Impact Through Time | |
| 撤回：揭示亲炎性巨噬细胞在先兆子痫母胎界面免疫网络失衡中的关键作用 | Fei, H. | N/A | WITHDRAWN: Unveiling the Crucial Role of Pro-inflammatory Macrophages in the Immune Network Imbalance of the maternal-fetal interface with Preeclampsia | |
| 溶酶体信号通路影响心脏节律，并调节心房功能。 | Capel, R. A. | N/A | Lysosomal signalling pathways influence heart rhythm, and regulate atrial function | |
| 多组学分析与机器学习预测：在存在配子和胚胎的情况下输卵管的反应 | Finnerty, R. M. | N/A | Multi-omics analyses and machine learning prediction of oviductal responses in the presence of gametes and embryos | |
| 成人颞叶新皮层第1层兴奋性突触小体的超微结构亚层特异性多样性 | Rollenhagen, A. | N/A | Ultrastructural sublaminar-specific diversity of excitatory synaptic boutons in layer 1 of the adult human temporal lobe neocortex | |
| 脂肪组织中的芳香化酶通过磷酸盐调节在雄性小鼠中发挥骨保护作用。 | Ikedo, A. | N/A | Aromatase in adipose tissue exerts an osteoprotective function in male mice via phosphate regulation | |
| 果蝇（Drosophila melanogaster）中的化学配偶选择模仿 | Mitchell, B. | N/A | Chemical mate choice copying in Drosophila melanogaster | |
| 发现了一种新型鞭虫物种，即T. incognita，其在科特迪瓦患者中对阿苯达唑-伊维菌素治疗的敏感性较低，通过粪便DNA代谢条形码技术鉴定。 | Venkatesan, A. | N/A | Discovery of a novel Trichuris species, T. incognita, with low sensitivity to albendazole-ivermectin treatment in Cote d'Ivoire patients, identified through fecal DNA metabarcoding | |
| 细胞分裂素作为系统信号，协调拟南芥的生殖努力。 | Volkava, D. | N/A | Cytokinin acts as a systemic signal coordinating reproductive effort in Arabidopsis | |
| 一个动力学简单行走模型修正了恢复速率的定义 | Hosseini-Yazdi, S.-S. | N/A | A Powered Simple Walking Model Modifies the Rate of Recovery Definition | |
| 小鼠脑中七个kisspeptin能神经元群体的综合化学分型和性腺调控 | Hernandez, V. S. | N/A | A comprehensive chemotyping and gonadal regulation of seven kisspeptinergic neuronal populations in the mouse brain | |
| HIV-1 Vif破坏了动粒处的磷酸酶反馈调节，导致明显的伪中期停滞 | Ghone, D. | N/A | HIV-1 Vif disrupts phosphatase feedback regulation at the kinetochore, leading to a pronounced pseudo-metaphase arrest | |
| 大西洋沟虾（Palaemon varians Leach, 1814）的蜕皮周期与刚毛发育（十足目：真虾下目：长臂虾科） | Kim, K. | N/A | Moult cycle and setal development of the Atlantic ditch shrimp Palaemon varians Leach, 1814 (Decapoda: Caridea: Palaemonidae) | |
| 胆碱能信号对鸣禽的鸣唱前运动回路进行差异化调控，以稳定鸣唱。 | Xu, N. | N/A | Cholinergic signaling differentially regulates song premotor circuits to stabilize songs in songbirds | |
| 人类CCR4-NOT全局调控基因表达，是一种新型逆转录转座子激活的沉默因子。 | Kulkarni, S. | N/A | Human CCR4-NOT globally regulates gene expression and is a novel silencer of retrotransposon activation | |
| 调控因子的反相聚集塑造基因爆发 | Li, B. | N/A | Anti-phase clustering of regulatory factors shapes gene bursting | |
| 化石多样化速率的明显时间尺度变化是由抽样偏差引起的。 | Reijenga, B. R. | N/A | Apparent timescaling of fossil diversification rates is caused by sampling bias | |
| 海马结构中社会知识的自我中心锚定与调整 | Rodriguez Aramendia, M. | N/A | Egocentric anchoring-and-adjustment of social knowledge in the hippocampal formation | |
| 编码于自我扩增RNA中的广谱免疫抑制作用能够实现非细胞毒性、非免疫刺激性的可逆转基因表达。 | Lim, T. K. Y. | N/A | Broad-spectrum immune suppression encoded inself-amplifying RNA enables non-cytotoxic, non-immunostimulatory, reversible transgene expression | |
| 编码于自我扩增RNA中的广谱免疫抑制作用能够实现非细胞毒性、非免疫刺激性的可逆转基因表达。 | Lim, T. K. Y. | N/A | Broad-spectrum immune suppression encoded in self-amplifying RNA enables non-cytotoxic, non-immunostimulatory, reversible transgene expression | |
| 疟原虫裂殖子单细胞RNA测序揭示，寄生虫通过激活基因网络为进入红细胞做准备。 | Piel, L. | N/A | Single cell RNA-sequencing of malaria merozoites reveals that the parasite prepares for life within the red blood cell by activating a gene network | |
| 撤回：来自登革病毒2型感染的血管内皮细胞的灭活条件培养基对上皮细胞愈合的影响：活细胞成像分析。 | Hincapie, V. | N/A | WITHDRAWN: Effect of inactivated conditioned media from DENV-2-infected endothelial cells on epithelial cell healing: live cell imaging analysis. | |
| 芜菁黄化病毒颗粒的结构。读取穿透域是如何暴露在衣壳表面的？ | Lai-Kee-Him, J. | N/A | Structure of the turnip yellows virus particles. How is the readthrough domain exposed on the capsid surface? | |
| 前膜和包膜蛋白对蜱传脑炎病毒结构、致病性和趋向性的影响 | Rosendal, E. | N/A | The influence of the pre-membrane and envelope proteins on structure, pathogenicity and tropism of tick-borne encephalitis virus | |
| 非裂解性复制病毒递送IL15超级激动剂增强抗肿瘤免疫并延长胶质母细胞瘤生存期 | Haddad, A. F. | N/A | Non-lytic replicating viral delivery of an IL15 superagonist enhances antitumor immunity and extends survival in glioblastoma | |
| 光流解析作为因果源分离：一种从光流中同时提取物体和自身运动信息的计算模型 | Scherff, M. | N/A | Flow parsing as causal source separation: A computational model for concurrent retrieval of object and self-motion information from optic flow | |
| 细菌双组分信号传导网络中激酶和效应子信号传导逻辑的变化 | Swingle, D. | N/A | Variations in kinase and effector signaling logic in a bacterial two component signaling network | |
| 大规模定量交联质谱技术揭示了细胞器、细胞和组织中蛋白质构象可塑性的新见解 | Keller, A. | N/A | Large-Scale Quantitative Cross-Linking and Mass Spectrometry Provides New Insight on Protein Conformational Plasticity within Organelles, Cells, and Tissues | |
| SARM1激活通过两步液-固相变促进轴突退化 | Zhang, W. | N/A | SARM1 Activation Promotes Axonal Degeneration Via a Two-Step Liquid-to-Solid Phase Transition | |
| 网格蛋白通过共同维持高尔基体的结构-功能关系来支持细胞外基质分泌。 | Thompson, G. | N/A | Golgins support extracellular matrix secretion by collectively maintaining the Golgi structure-function relationship | |
| 溶组织内阿米巴中富含谷氨酸-赖氨酸（EK）的RabD2基序通过自相互作用及多泡体途径调控病原体的发病机制 | Navyaka, P. | N/A | Glutamic acid-lysine (EK) rich motif of RabD2 self-associates and regulates pathogenesis through multivesicular bodies pathway in E. histolytica | |
| ALS和FTD相关蛋白Annexin A11和CHMP2B在膜修复中依次发挥作用 | Heffner, C. M. | N/A | The ALS- and FTD-associated proteins Annexin A11 and CHMP2B act sequentially in membrane repair | |
| 迈向鲁棒机器嗅觉：去偏GC-MS数据提升前列腺癌从尿液挥发性物质中的诊断 | Rotteveel, A. | N/A | Towards robust machine olfaction: debiasing GC-MS data enhances prostate cancer diagnosis from urine volatiles | |
| 细菌类泛素蛋白的结构多样性与寡聚化 | Gong, M. | N/A | Structural diversity and oligomerization of bacterial ubiquitin-like proteins | |
| 微生物物种树重建的系统评估方法 | Weiner, S. | N/A | A systematic assessment of phylogenomic approaches for microbial species tree reconstruction | |
| Ezh2在正常小脑颗粒神经元发育过程中延迟分化基因的激活，并在髓母细胞瘤中发挥类似作用。 | Purzner, J. | N/A | Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma | |
| 在一种分化的细菌泛素化途径中蛋白质共轭的机制基础 | Ye, Q. | N/A | Mechanistic basis for protein conjugation in a diverged bacterial ubiquitination pathway | |
| 计算分析以评估降主动脉瘤中的血流动力学力 | Duca, F. | N/A | Computational analysis to assess hemodynamic forces in descending thoracic aortic aneurysms | |
| 在非常罕见的祖B细胞条件下，多样化的启动结果 | Madden, P. J. | N/A | Diverse priming outcomes under conditions of very rare precursor B cells | |
| 成对相互作用和连续瓶颈效应有助于解释多物种微生物群落中的物种组成 | Lele, K. | N/A | Pairwise interactions and serial bottlenecks help explain species composition in a multi-species microbial community | |
| 具有两种不同DNA结合模式的保守ComP结构——使用AlphaFold3、RoseTTAFold2NA、Chai-1进行系统建模及在HADDOCK中重新对接 | Helsem, S. A. | N/A | The conserved ComP structure with two distinct DNA binding modes - systematic modeling with AlphaFold3, RoseTTAFold2NA, Chai-1 and re-docking in HADDOCK | |
| 一种偏好腺嘌呤碱基编辑器，具有最小的旁观者效应和脱靶编辑 | Shang, M. | N/A | A motif preferred adenine base editor with minimal bystander and off-targets editing | |
| 抗生素治疗和微生物群减少会减缓刺胞动物的再生过程。 | Da-Anoy, J. | N/A | Antibiotic treatment and microbiome depletion slow cnidarian regeneration | |
| 网络共同体：连接数据、知识和方法，构建和评估特定情境下的生物网络 | Paton, V. | N/A | NetworkCommons: bridging data, knowledge and methods to build and evaluate context-specific biological networks | |
| 复制压力标志物磷酸化-RPA2预测同源重组功能正常的卵巢癌对铂类和PARP抑制剂的反应 | Schab, A. | N/A | Replication stress marker phospho-RPA2 predicts response to platinum and PARP inhibitors in homologous recombination-proficient ovarian cancer | |
| 乙型肝炎核心相关抗原在既往乙型肝炎病毒感染患者病毒基因组整合中的作用 | Saito, T. | N/A | Involvement of Hepatitis B Core-Related Antigen in Viral Genome Integration in Patients With Prior Hepatitis B Virus Infection | |
| S-1生物标志物对接受辅助S-1化疗的老年肺癌患者衰老和预后的影响：Setouchi肺癌研究组1201研究的伴随结果 | Soh, J. | N/A | Implication of S-1 biomarkers on aging and prognosis in elderly patients with lung cancer treated by adjuvant S-1 chemotherapy: Accompanying results of the Setouchi Lung Cancer Group Study 1201 | |
| 细胞代谢通量分布的深度学习预测寿命 | Hilsabeck, T. A. | N/A | Deep Learning of Cellular Metabolic Flux Distributions Predicts Lifespan | |
| 多巴胺在有无反馈的情况下都会影响运动学习表现。 | Leow, L.-A. | N/A | Dopamine alters motor learning performance in the presence and absence of feedback | |
| GRNIX：一种基于图神经网络的可解释基因调控网络推断框架，用于自身免疫性疾病中的XAI | Manai, M. M. | N/A | GRNIX: A Graph Neural Network Framework for Explainable Gene Regulatory Network Inference in Autoimmune Diseases Using XAI | |
| 改进的深度学习预测TCR-HLA关联 | Li, F. | N/A | Improved Deep Learning Prediction of TCR-HLA Association | |
| 间隙DNA的序列依赖性液晶有序化 | Kodikara, S. | N/A | Sequence-Dependent Liquid Crystalline Ordering of Gapped DNA | |
| 高度有序脂质双层中玻璃态动力学的特征及软动态通道的出现 | Sureshkumar, H. | N/A | Signatures of glassy dynamics in highly ordered lipid bilayers with emergence of soft dynamic channels | |
| 基于荧光技术的活细胞成像识别出跳过第14外显子的肝细胞生长因子受体（MET）降解剂 | Mallareddy, J. R. | N/A | Fluorescence based live cell imaging identifies exon 14 skipped hepatocyte growth factor receptor (MET) degraders | |
| 中国上二叠统闹包沟组四足动物群：一种新的中型前棱蜥类——阴山龙属新种阴山龙及其对前棱蜥类系统发育关系的启示 | Yi, J. | N/A | The tetrapod fauna of the upper Permian Naobaogou Formation of China: a new mid-sized pareiasaur Yinshanosaurus angustus gen. et sp. nov. and its implication for the phylogenetic relationship of pareiasaurs | |
| TGFbeta-LRRC15轴的关键调控元件预测了多种癌症类型的疾病进展及免疫治疗抵抗 | Storey, C. M. | N/A | Key Regulatory Elements of the TGFbeta-LRRC15 Axis Predict Disease Progression and Immunotherapy Resistance Across Cancer Types | |
| 玉米黑粉菌（Ustilago maydis）通过破坏宿主细胞中的碳水化合物信号网络来诱导细胞肥大。 | Lee, Y. J. | N/A | Ustilago maydis disrupts carbohydrate signaling networks to induce hypertrophy in host cells | |
| 适应性生物系统的累积剂量反应 | Gupta, A. | N/A | Cumulative dose responses for adapting biological systems | |
| 鱼类微小RNA对热应激的响应：全球变暖背景下对水产养殖与保护的启示与影响 | Lin, T. | N/A | Fish MicroRNA Responses to Thermal Stress: Insights and Implications for Aquaculture and Conservation Amid Global Warming | |
| 大脑-网格模型：神经同步、可塑性和一致性的统一框架 | Ballus, A. | N/A | THE BRAIN-MESH MODEL: A UNIFIED FRAMEWORK FORNEURAL SYNCHRONY, PLASTICITY, AND COHERENCE | |
| 人类大脑区域脑熵（BEN）的细胞类型基础 | Song, D. | N/A | The cell-type underpinnings of regional brain entropy (BEN) in human brain | |
| 通过纵向分子亚型分析揭示SARS-CoV-2宿主反应的异质性 | Wang, K. | N/A | Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping | |
| 唐氏综合征中失调的气道上皮抗病毒免疫削弱了III型干扰素反应，并在呼吸道合胞病毒感染期间加剧了气道炎症。 | Chorvinsky, E. | N/A | Dysregulated airway epithelial antiviral immunity in Down Syndrome impairs type III IFN response and amplifies airway inflammation during RSV infection. | |
| 肠道损伤的新型免疫标志物，指示HIV-1状态和/或亚临床动脉粥样硬化 | Moreira Gabriel, E. | N/A | Novel Immunological Markers of Intestinal Impairment Indicative of HIV-1 Status and/or Subclinical Atherosclerosis | |
| Bin Chicken：针对目标宏基因组共组装，高效恢复新颖基因组 | Aroney, S. T. N. | N/A | Bin Chicken: targeted metagenomic coassembly for the efficient recovery of novel genomes | |
| RetS通过感知神经递质去甲肾上腺素和肾上腺素来调节铜绿假单胞菌的毒力。 | Zhou, Y. | N/A | RetS senses neurotransmitter norepinephrine and adrenergic agents to regulate Pseudomonas aeruginosa virulence | |
| 益生菌搅拌酸奶对大鼠代谢功能障碍相关脂肪肝疾病的预防作用 | Sallam, M. S. | N/A | Probiotic Stirred Yogurt Mediated the Prevention of Metabolic Dysfunction-Associated Steatotic Liver Disease in Rats | |
| 在GKAP支架蛋白与LC8枢纽蛋白之间拓扑约束的多价复合物中，存在残余的灵活性。 | Nagy-Kanta, E. | N/A | Residual flexibility in the topologically constrained multivalent complex between the GKAP scaffold and LC8 hub proteins | |
| 细菌硫辛酰胺蛋白连接酶在哺乳动物中拯救硫辛酰化及呼吸缺陷 | Hu, Z. | N/A | Bacterial lipoate protein ligases rescue lipoylation and respiration deficiency in mammals | |
| 全球微型浮游生物生物地理分布通过宏基因组和气候数据整合揭示 | Salazar, V. W. | N/A | Global picoplankton biogeography revealed by metagenomic and climatic data integration | |
| 委内瑞拉三种空中捕食蝙蝠的饮食及其生态位划分 | Azofeifa Romero, Y. | N/A | Diet and trophic niche partitioning of three aerial hawking bat species in Venezuela | |
| 使用堆叠模型和物种特征预测食物网中的缺失链接 | Van Kleunen, L. B. | N/A | Predicting missing links in food webs using stacked models and species traits | |
| 基于三联体（triplet）的物种树估算方法对基因树根节点（或其缺失）的鲁棒性 | Zaman, T. A. | N/A | On the robustness to gene tree rooting (or lack thereof) of triplet-based species tree estimation methods | |
| 单花蝇子草的染色体规模基因组组装和连锁图谱揭示了快速进化植物物种的重组景观 | Osborne, O. G. | N/A | Chromosome-scale genome assembly and linkage map for Silene uniflora reveal the recombination landscape in a rapidly evolving plant species | |
| 果蝇（Drosophila melanogaster）中高度转录且具有性别偏向基因的非最优密码子选择的证据 | Whittle, C. A. | N/A | Evidence for non-optimal codon choice in highly transcribed sex-biased genes of Drosophila melanogaster | |
| 综合方法优先考虑孤儿GPR61基因组区域在组织特异性调节生物钟类型中的作用 | Tchio, C. | N/A | An integrative approach prioritizes the orphan GPR61 genomic region in tissue-specific regulation of chronotype | |
| 肌萎缩侧索硬化症中的性别特异性DNA甲基化差异 | Grant, O. | N/A | Sex-specific DNA methylation differences in Amyotrophic lateral sclerosis | |
| 潜在抑制、发散思维与目击记忆的关系：一项关于对无关刺激注意的研究 | Badiola-Lekue, I. | N/A | The Relationship between Latent Inhibition, Divergent Thinking, and Eyewitness Memory: A Study on Attention to Irrelevant Stimuli | |
| 通过活性位点半胱氨酸对SARS-CoV-2 NiRAN结构域进行共价抑制 | Hernandez, G. | N/A | Covalent inhibition of the SARS-CoV-2 NiRAN domain via an active-site cysteine | |
| 印楝油纳米乳剂对人类神经母细胞瘤SH-SY5Y细胞系中由淀粉样β1-40诱导的抗阿尔茨海默病效应 | Govindaswamy, B. | N/A | Anti Alzheimer's effects of Neem oil nanoemulsion against Amyloid β1-40 induced in human neuroblastoma SH-SY5Y cell line | |
| 兔心生物人工组织：灌注去细胞化与特性分析 | Seitzhaparova, B. | N/A | Rabbit Heart Bioartificial Tissue: Perfusion Decellularization and Characterization | |
| 评估用于病毒基因组学的长读长映射工具 | Baudeau, T. | N/A | Assessing Long-Read Mappers for Viral Genomics | |
| CNV-Profile回归：一种新的全基因组测序数据拷贝数变异关联分析方法 | Si, Y. | N/A | CNV-Profile Regression: A New Approach for Copy Number Variant Association Analysis in Whole Genome Sequencing Data | |
| 解剖区域特异性转录组特征及上皮细胞在翼状胬肉炎症中的作用：一项多组学分析 | Song, C. | N/A | Anatomical Region-Specific Transcriptomic Signatures and the Role of Epithelial Cells in Pterygium Inflammation: A Multi-Omics Analysis | |
| 利用眼动持续同调性进行神经障碍筛查 | He, D. | N/A | Leveraging Persistent Homology of Eye Movements for Neural Disorder Screening | |
| 通过计算机模拟和RBP结合的解释，揭示了m6A-RBP相互作用 | Liu, J. | N/A | In-silico modeling and interpretation of RBP binding disentangle m6A-RBP interaction | |
| 用于通过光学控制跨膜离子通信的开关纳米孔 | Wang, X. | N/A | ON-OFF nanopores for optical control of transmembrane ionic communication | |
| Tau聚集受其投影域突变的影响而发生改变 | Mason-Chalmers, K. | N/A | Tau Aggregation is Altered by Mutations in its Projection Domain | |
| 腹水可防止铁死亡并促进卵巢癌的腹腔扩散 | Setayeshpour, Y. | N/A | Ascitic fluid protects against ferroptosis and enables the peritoneal spread of ovarian cancer | |
| FAK抑制通过DNA甲基化介导的DAB2基因重新激活抑制乳腺癌进展 | Lim, S. | N/A | FAK inhibition suppresses breast cancer progression via DNA methylation-mediated DAB2 gene reactivation | |
| 抑制Wnt通路效应因子TCF7L2可逆转小鼠肠道癌症中的致命恶病质 | Leong, M. L. | N/A | Repression of the Wnt pathway effector TCF7L2 reverses lethal cachexia in mice with intestinal cancers | |
| 定量磁共振成像测量捕捉到胰腺癌和基质对新型KRAS抑制剂的反应 | Gupta, M. | N/A | Quantitative MRI Measurements Capture Pancreatic Cancer and Stroma Reactions to New KRAS Inhibitor | |
| 豌豆白粉菌（Erysiphe pisi）是一种专性寄生真菌，主要感染豌豆（Pisum sativus）和扁豆（Lathyrus sativus）。扁豆是一种重要的粮食和饲料作物，在亚洲和非洲部分地区广泛种植。然而，扁豆对豌豆白粉菌的抗性因品种而异，这限制了其在这些地区的可持续种植。为了更好地了解扁豆对豌豆白粉菌的抗性机制，我们进行了比较转录组学分析，比较了两个扁豆品种（Ls-1和Ls-2）在接种豌豆白粉菌后的转录组变化。我们发现，两个品种在接种豌豆白粉菌后表现出不同的转录组响应，表明它们对病原体的抗性机制存在差异。具体而言，Ls-1品种在接种豌豆白粉菌后上调了多个与防御相关的基因，包括几丁质酶、β-1,3-葡聚糖酶和抗病蛋白基因，而Ls-2品种则没有表现出类似的上调。此外，我们还发现Ls-1品种在接种豌豆白粉菌后下调了多个与生长和发育相关的基因，这可能有助于将资源重新分配给防御反应。我们的研究结果表明，扁豆对豌豆白粉菌的抗性是一个复杂的性状，涉及多个基因和途径的调控。未来的研究应进一步探索这些基因和途径在扁豆抗病性中的作用，以开发更有效的抗病品种。 | Marques, R. M. | N/A | Comparative transcriptomics of Lathyrus sativus reveals accession-specific resistance responses against Erysiphe pisi | |
| 通过综合生态基因组学揭示全球栗树害虫入侵的由下而上和由上而下的控制机制 | Zitoun, J.-l. | N/A | Unravelling the bottom-up and top-down control of a worldwide chestnut tree pest invader through integrative ecological genomics | |
| 细胞通过进入一种类似静止的状态，以高效率转化为神经元。 | Beitz, A. M. | N/A | Cells transit through a quiescent-like state to convert to neurons at high rates | |
| 三级淋巴结构作为克罗恩病治疗靶点：TNFα阻断剂的调节作用 | Nagase, Y. | N/A | Tertiary lymphoid structure as a therapeutic target of Crohns disease: modulation by TNFα blockade | |
| 利用受激辐射损耗显微技术揭示活体白色念珠菌的超微结构 | Baxter, K. J. | N/A | Revealing the Ultrastructure of Live Candida albicans using Stimulated Emission Depletion Microscopy | |
| 深海冷泉中的微生物毒力组和抗性组对公共健康构成的风险极小。 | Zhang, T. | N/A | Microbial virulome and resistome in deep-sea cold seeps pose minimal public health risks | |
| SARS-CoV-2 nsp1中自然发生的N端突变影响先天免疫调节，但不影响病毒毒力 | Rani, R. | N/A | Naturally occurring N-terminal mutations in SARS-CoV-2 nsp1 impact innate immune modulation but do not affect virus virulence | |
| 慢性感染SARS-CoV-2患者体内遗传多样性的多种模式 | Rutsinsky, N. | N/A | Diverse patterns of intra-host genetic diversity in chronically infected SARS-CoV-2 patients | |
| 多个线虫物种在整个神经系统中进化变化的分子模式 | Toker, I. A. | N/A | Molecular patterns of evolutionary changes throughout the whole nervous system of multiple nematode species | |
| 解决斑纹蟾蜍（Bufonidae: Incilius marmoreus）的分类地位：基于2RAD的系统地理学研究，包括墨西哥韦拉克鲁斯州的一个孤立种群 | Wang, K. | N/A | Resolving the Taxonomic Status of the Marbled Toad (Bufonidae: Incilius marmoreus): 2RAD-based Phylogeography Including an Isolated Population in Veracruz, Mexico | |
| 多个性状的协同进化使蝴蝶拥有了一个假头 | Yumnam, T. | N/A | Correlated evolution of multiple traits gives butterflies a false head | |
| 全基因组关联研究确定了冬季和早春耐寒性的有希望的QTL，作为深入遗传分析和在冬蚕豆（Vicia faba L.）育种中实施的基础。 | Windhorst, A. | N/A | Genome-wide association studies identify promising QTL for freezing tolerance in winter and early spring as a basis for in-depth genetic analysis and implementation in winter faba bean (Vicia faba L.) breeding | |
| 一种用于评估应用于野生海洋鱼类的基因组动物模型鲁棒性的新框架 | Thia, J. A. | N/A | A novel framework for assessing the robustness of genomic animal models applied to a wild marine fish | |
| 苏门答腊猩猩母亲在母性行为的表现程度和轨迹上存在差异。 | Revathe, T. | N/A | Sumatran orangutan mothers differ in the extent and trajectory of their expression of maternal behaviour | |
| 斑胸草雀社会网络多层结构的社会和空间驱动因素 | Zhang, Y. | N/A | Social and spatial drivers of the multitiered structure of zebra finch social networks | |
| 对下丘脑表型的调查确定了雄性和雌性小鼠中MYT1L单倍体不足的分子和行为后果。 | Dougherty, J. D. | N/A | A survey of hypothalamic phenotypes identifies molecular and behavioral consequences of MYT1L haploinsufficiency in male and female mice. | |
| 狐獴中的发声修饰：弱联结的从属者对支配者的回应中发出更多的叫声 | Demartsev, V. | N/A | Vocal grooming in meerkats: weakly bonded subordinatescall more in response to dominants | |
| 衰老对黑猩猩使用石器工具的参与度和效率的影响因个体而异。 | Howard-Spink, E. | N/A | Old age variably impacts chimpanzee engagement and efficiency in stone tool use | |
| 在体外高保真地将多种合成货物包装到封装蛋白笼中 | Szyszka, T. N. | N/A | High-fidelity in vitro packaging of diverse synthetic cargo into encapsulin protein cages | |
| 肝细胞癌的综合转录组分析：揭示不同病因中的共享与独特分子特征 | Khorsand, B. | N/A | Comprehensive Transcriptomic Analysis of Hepatocellular Carcinoma: Uncovering Shared and Unique Molecular Signatures Across Diverse Etiologies | |
| 洛伦兹对基因集富集分析的看法：基因集富集分析与财富不平等衡量方法的相似性与差异 | Pagnotta, S. M. | N/A | The Lorenz's side of Gene Set Enrichment Analysis: Similarity and divergences of the Gene Set Enrichment Analysis from the measure of wealth inequality | |
| NhaA中Na+/H+反向转运的分子机制 | Xie, T. | N/A | Molecular mechanism of Na+/H+ antiporting in NhaA | |
| 雌激素受体信号转录程序与人类激素受体阳性乳腺癌中的免疫逃逸相关 | Shimada, K. | N/A | An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancer | |
| 同时抑制COX-1和COX-2不足以引发与长期使用非甾体抗炎药（NSAID）相关的肠病。 | Barekat, K. | N/A | Concomitant suppression of COX-1 and COX-2 is insufficient to induce enteropathy associated with chronic NSAID use | |
| 氧化性损伤对肺线粒体DNA是化学性肺损伤发展的关键因素 | Dubey, S. | N/A | Oxidative Injury to Lung Mitochondrial DNA is a Key Contributorfor the Development of Chemical Lung Injury | |
| 可可基因组序列揭示了黄酮类生物合成的见解 | Marin Recinos, M. F. | N/A | Cacao genome sequence reveals insights into the flavonoid biosynthesis | |
| DNA复制时序揭示了转录和脆弱性的全基因组特征 | Berkemeier, F. | N/A | DNA replication timing reveals genome-wide features of transcription and fragility | |
| 评估单细胞基因表达动力学对联合抗生素生存能力的预测能力 | Alnahhas, R. N. | N/A | Evaluating the predictive power of combined gene expression dynamics from single cells on antibiotic survival | |
| 区域特异性图片命名受益于焦点tDCS的效果取决于老年人的基线表现 | Yucel, A. | N/A | Regionally specific picture naming benefits of focal tDCS are dependent on baseline performance in older adults | |
| 同种社交性受联想学习回路调节。 | Lobato-Rios, V. | N/A | Conspecific sociability is regulated by associative learning circuits | |
| 叶酸可预防草原田鼠因发育期接触拟除虫菊酯而导致的自闭症相关表型。 | Saferin, N. | N/A | Folate prevents the autism-related phenotype caused by developmental pyrethroid exposure in prairie voles | |
| 鼻内丹曲洛林纳米颗粒抑制5XFAD小鼠脑内炎症性细胞焦亡 | Bhuiyan, P. | N/A | Intranasal dantrolene nanoparticles inhibit inflammatory pyroptosis in 5XFAD mice brains | |
| Parp1缺失可挽救xrcc1突变斑马鱼的小脑发育不良 | Semenova, S. A. | N/A | Parp1 deletion rescues cerebellar hypotrophy in xrcc1 mutant zebrafish | |
| 使用基于定量MRI的水参考的2D 1H-MRSI对脑代谢物进行绝对定量 | Thomas, D. C. | N/A | Absolute quantification of cerebral metabolites using 2D 1H-MRSI with quantitative MRI-based water reference | |
| 一种多用途的鼠标模型，用于推进神经退行性疾病中人源小胶质细胞移植研究 | De Strooper, B. | N/A | A versatile mouse model to advance human microglia transplantation research in neurodegenerative diseases | |
| 基于多模态、多方面的成像人类大脑白质图谱 | Zhou, J. | N/A | Multimodal, multifaceted Imaging-based Human Brain White Matter Atlas | |
| 虚拟大脑将经颅磁刺激引发的电位与重度抑郁症中抑制性神经递质的变化联系起来。 | Hofsähs, T. | N/A | The Virtual Brain links transcranial magnetic stimulation evoked potentials and inhibitory neurotransmitter changes in major depressive disorder | |
| 直观的物理推理并不通过语言进行中介，也不是仅依赖于领域通用的抽象表征。 | Kean, H. H. | N/A | Intuitive physical reasoning is not mediated by linguistic nor exclusively domain-general abstract representations | |
| 使用量子点和去卷积技术的快速光稳定扩展显微镜 | Gunawardhana, L. | N/A | Fast Photostable Expansion Microscopy Using QDots andDeconvolution | |
| 通过计算建模揭示了人类和猴子对三维和运动刺激的不同决策过程 | Rangotis, R. | N/A | Distinct decision processes for 3D and motion stimuli in both humans and monkeys revealed by computational modelling | |
| 增加的不情愿囊泡通过GPR55在小脑浦肯野细胞轴突末梢中导致突触抑制 | Inoshita, T. | N/A | Increased reluctant vesicles underlie synaptic depression by GPR55 in axon terminals of cerebellar Purkinje cells | |
| CRISPRa介导的2C样状态、全能性和细胞死亡中Dux-MERVL轴的解离 | Chammas, P. | N/A | CRISPRa-mediated disentanglement of the Dux-MERVL axis in the 2C-like state, totipotency and cell death | |
| 糖基转移酶POGLUT1调控小鼠肌肉干细胞的发育和维持 | Cho, S. | N/A | The glycosyltransferase POGLUT1 regulates muscle stem cell development and maintenance in mice | |
| 全面蛋白质组学、超微结构及功能分析：低温保存对海洋贻贝卵细胞的影响 | Blanco, S. | N/A | Comprehensive Proteomic, Ultrastructural and Functional Analysis of Cryopreservation Effects on Marine Mussel Oocytes | |
| 城市化对芝加哥地区美洲知更鸟（Turdus migratorus）健康的影响 | Riccardi, A. | N/A | Impacts of urbanization on the health of American Robins (Turdus migratorus) in Chicagoland | |
| 测试蜜蜂的峰终法则：当最终奖励令人失望时，蜜蜂对高奖励序列缺乏偏好 | Armand, M. | N/A | Testing the peak-end rule in bumblebees: lack of preference for a higher-reward sequence when the final reward is disappointing | |
| 雌性小鼠超声波发声的频率较低，在与无声雄性互动时，其发声频率并不受发情状态的影响。 | Malone, C. A. | N/A | Rates of female mouse ultrasonic vocalizations are low and are not modulated by estrous state during interactions with muted males | |
| 脊髓刺激模型中的频率依赖性和电容性组织电特性 | Khadka, N. | N/A | Frequency-dependent and capacitive tissue electrical properties in spinal cord stimulation models | |
| ApoDock：用于柔性分子对接的配体条件侧链包装 | Luo, D. | N/A | ApoDock: Ligand-Conditioned Sidechain Packing for Flexible Molecular Docking | |
| DeepAssembly2：基于域-域相互作用的蛋白质复合物结构组装网络服务器 | Xia, Y. | N/A | DeepAssembly2: A Web Server for Protein Complex Structure Assembly Based on Domain-Domain Interactions | |
| 饥饿和荷尔蒙状态的整合调控着面向婴儿的攻击行为 | Cao, M. | N/A | Integration of hunger and hormonal state gates infant-directed aggression | |
| 胚胎生成的中间神经元（EGINs）在嗅球中表现出独特的发展程序和分层结构。 | Spence, N. J. | N/A | Embryonically generated interneurons (EGINs) exhibit a distinctive developmental program and lamination in the olfactory bulb | |
| H通道和m通道的过度表达通过损害抑制性神经元处理相关输入的能力，促进了类似癫痫事件的发生。 | Rich, S. | N/A | H- and m-channel overexpression promotes seizure-like events by impairing the ability of inhibitory neurons to process correlated inputs | |
| 谷氨酰胺分解促进易患狼疮小鼠的滤泡辅助性T细胞功能 | Choi, S. C. | N/A | Glutaminolysis promotes the function of follicular helper T cells in lupus-prone mice | |
| 从濒危的塔斯马尼亚恶魔（Sarcophilus harrisii）肿瘤细胞中分离出一种类似病毒的传染性哺乳动物病毒 | Melade, J. | N/A | Isolation of an infectious mammalian chu-like virus from tumor cells of the endangered Tasmanian devil (Sarcophilus harrisii) | |
| 细菌菌落活检：通过细胞光谱指纹技术实现异质细胞类型的空间辨别 | Abbaszade, G. | N/A | Bacterial colony biopsies: spatial discrimination of heterogeneous cell types by cytometric fingerprinting | |
| M66I衣壳变异体对Lenacapavir耐药的结构和机制基础 | Briganti, L. | N/A | Structural and Mechanistic Bases for Resistance of the M66I Capsid Variant to Lenacapavir | |
| 毒力决定因子蛋白E是一种弗朗西斯菌VI型分泌系统效应蛋白，能够调节宿主细胞的死亡。 | Adams, N. | N/A | Pathogenicity determinant protein E is a Francisella type VI secretion system effector protein that modulates host death | |
| 评估宽吻海龙（Syngnathus typhle）肠道微生物群组成中噬菌体的影响 | Parker, J. | N/A | Evaluating bacteriophage impact on gut microbiome composition in broad-nosed pipefish (Syngnathus typhle) | |
| HsbA抑制铜绿假单胞菌静止期生物膜的形成。 | Pulido Sanchez, M. | N/A | HsbA represses stationary phase biofilm formation in Pseudomonas putida | |
| Rigosertib可逆转与RAF1相关的努南综合征中的肥厚型心肌病 | Legler, L. | N/A | Rigosertib reverses hypertrophic cardiomyopathy in RAF1-associated Noonan syndrome | |
| 从犬类脐带中非病毒诱导的多能干细胞的衍生 | Yamazaki, A. | N/A | Non-viral derivation of induced pluripotent stem cells from the canine umbilical cord | |
| 内耳神经元的脱离时间决定了它们的空间分布和目标神经支配。 | Saini, S. S. J. S. | N/A | Timing of delamination of inner ear neurons specifies their topography and target innervation | |
| 入侵型黄蜂Vespa velutina nigrithorax比另外两种膜翅目昆虫——普通黄蜂Vespa vulgaris和蜜蜂Bombus terrestris——更容易受到昆虫病原真菌的感染。 | Lacombrade, M. | N/A | Invasive Vespa velutina nigrithorax hornets are more susceptible to entomopathogenic fungus than two other hymenopteran species, the wasp Vespa vulgaris and the bumblebee Bombus terrestris. | |
| 结构泛素有助于HECT连接酶Tom1的K48连接特异性 | Warner, K. | N/A | Structural ubiquitin contributes to K48 linkage-specificity of the HECT ligase Tom1 | |
| RalGAP肿瘤抑制复合物的结构与机制 | Rasche, R. | N/A | Structure and mechanism of the RalGAP tumor suppressor complex | |
| 胆固醇在人类平滑受体中的感知和转运的能量学 | Bansal, P. D. | N/A | Energetics of cholesterol perception and translocation in the human Smoothened receptor | |
| E3泛素连接酶TRIP12对氧化应激反应的动态调控 | Ingersoll, A. J. | N/A | Dynamic regulation of the oxidative stress response by the E3 ligase TRIP12 | |
| 接触图拓扑对RNA结构预测的影响 | Faber, C. | N/A | Influence of Contact Map Topology on RNA Structure Prediction | |
| 一种多功能的反CRISPR平台，用于光遗传学和化学遗传学控制广泛同源物中的CRISPR-Cas9和Cas12 | Brenker, L. | N/A | A Versatile Anti-CRISPR Platform for Opto- and Chemogenetic Control of CRISPR-Cas9 and Cas12 across a Wide Range of Orthologs | |
| 利用两阶段透明机器学习模型进行超高通量抗菌联合疗法筛选 | Reuter, M. M. | N/A | Ultra-high-throughput screening of antimicrobial combination therapies using a two-stage transparent machine learning model | |
| 特异性导航决定了多隔间环境中鼠标CA1的表征结构 | Pecirno, S. A. | N/A | Idiosyncratic navigation determines mouse CA1 representational structure in a multicompartment environment | |
| CRISPRi筛选揭示了lncRNA调控人类单核细胞生长的机制 | Flores-Arena, C. | N/A | CRISPRi Screen Uncovers lncRNA Regulators of Human Monocyte Growth | |
| 糖细菌部署了两种不同的IV型菌毛，推动了共生、宿主竞争和滑行运动。 | Grossman, A. S. | N/A | Saccharibacteria deploy two distinct Type IV pili, driving episymbiosis, host competition, and twitching motility | |
| 分泌性白细胞蛋白酶抑制剂影响伯氏疏螺旋体感染小鼠的关节周围炎症 | Yu, Q. | N/A | Secretory leukocyte protease inhibitor influences periarticular joint inflammation in B. burgdorferi-infected mice | |
| 结核分枝杆菌中一种新型放线菌特异性核糖体休眠因子 | Majumdar, S. | N/A | A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis | |
| 温度，而非植物品种，影响杀虫双链RNA在科罗拉多马铃薯甲虫中的效果。 | Darrington, M. | N/A | Temperature, but not plant cultivar, influence the efficacy of insecticidal dsRNA in Colorado potato beetle | |
| RNF20介导的H2B单泛素化保护停滞的复制叉并促进复制叉重启 | Nagaraju, G. | N/A | RNF20-mediated H2B monoubiquitination protects stalled forks and promotes fork restart | |
| 肾皮质细胞特异性氧化代谢 | Feola, K. | N/A | Cell-specific oxidative metabolism of the renal cortex | |
| iPSC衍生的肾脏类器官和管状模型比较分析 | Nunez Nescolarde, A. | N/A | Comparative analysis of iPSC-derived human kidney organoid and tubuloid models | |
| 通过针对宿主特异性引物设计实现内生真菌的有效扩增子测序，适用于纳米孔长读长测序 | He, T. | N/A | Effective metabarcoding of endophytic fungi through host-exclusive primer design for nanopore long-read sequencing | |
| 太平洋牡蛎OSHV-1抗性标记存在于第8号染色体上，并不影响其对河口弧菌感染的易感性。 | Surry, L. B. | N/A | The presence of the Pacific Oyster OSHV-1 resistance marker on chromosome 8 does not impact susceptibility to infection by Vibrio aestuarianus | |
| 基于Tiled PCR扩增的全基因组测序与系统发育分类加速了呼吸道合胞病毒基因组监测在加拿大的实施，作为一项试点研究 | Gao, R. | N/A | Tiled PCR amplification-based Whole Genome Sequencing and Phylogenetic Classification Accelerate the Implementation of Respiratory Syncytial Virus Genomic surveillance in Canada as a Pilot Study | |
| 聚集蛋白聚糖的透明质酸结合活性对其特异性插入神经元周围网（perineuronal nets）是重要的，但并非必要条件。 | Otsuka, M. Y. | N/A | The hyaluronan-binding activity of aggrecan is important, but not essential, for its specific insertion into perineuronal nets | |
| 解析真菌中III型聚酮合酶的功能多样性 | Sokolova, N. | N/A | Unravelling the functional diversity of type III polyketide synthases in fungi | |
| 利用生成式人工智能设计新型CAR-T细胞疗法 | Mergen, M. | N/A | Engineering de novo binder CAR-T cell therapies with generative AI | |
| mei-P26突变体的功能缺失性分析揭示了发育过程中CO模式机制的调控 | Berent, E. | N/A | Analysis of a hypomorphic mei-P26 mutation reveals developmental control of CO patterning mechanisms | |
| # BioRxiv 2024-11-24 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 一个简单的行为时间尺度突触可塑性模型，通过二进制突触和一次性学习，提供了内容可寻址记忆。 | Wu, Y. | N/A | A simple model for Behavioral Time Scale Synaptic Plasticity provides content addressable memory with binary synapses and one-shot learning | |
| 基于CRISPRi的筛选在iAssembloids中进行，以阐明神经元-胶质细胞相互作用 | Li, E. | N/A | CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions | |
| 竹林中的迷惑互动：喜马拉雅山东部混种鸟群中的种间关联 | Srinivasan, S. | N/A | Bamboozling Interactions: Interspecific associations within mixed-species bird flocks in bamboo in the Eastern Himalaya | |
| 使用ALDEx2进行RNA测序分析的显式尺度模拟 | Gloor, G. B. | N/A | Explicit Scale Simulation for analysis of RNA-sequencing withALDEx2 | |
| eIF3与高翻译效率mRNA的3'-UTR末端结合 | Mestre-Fos, S. | N/A | eIF3 engages with 3'-UTR termini of highly translated mRNAs | |
| 新测序的基因组揭示了特定蜻蜓（蜻蜓目：差翅亚目）基因家族扩张的模式 | Tolman, E. R. | N/A | Newly Sequenced Genomes Reveal Patterns of Gene Family Expansion in select Dragonflies (Odonata: Anisoptera) | |
| edgeR v4：功能强大的测序数据差异分析工具，扩展了功能并改进了对小计数和大数据集的支持 | Chen, Y. | N/A | edgeR v4: powerful differential analysis of sequencing data with expanded functionality and improved support for small counts and larger datasets | |
| 基于实时Förster共振能量转移检测系统（FedEcs）监测的纳米载体药物释放及中风后微血栓血脑屏障穿透 | Khalin, I. | N/A | Nanocarrier Drug Release and Blood-Brain Barrier Penetration at Post-Stroke Microthrombi Monitored by Real-Time Förster Resonance Energy Transfer-Based Detection System (FedEcs) | |
| SARS-CoV-2基因组的二级结构可预测核苷酸替代频率 | Hensel, Z. | N/A | Secondary structure of the SARS-CoV-2 genome is predictive of nucleotide substitution frequency | |
| 转录后模块化合成受体 | Zhang, X. | N/A | Post-Transcriptional Modular Synthetic Receptors | |
| 不对称干细胞分裂维持了组织细胞的遗传异质性。 | Bener, M. B. | N/A | Asymmetric stem cell division maintains genetic heterogeneity of tissue cells | |
| 互补的脊椎动物Wac模型表现出与DeSanto-Shinawi综合征相关的表型 | Lee, K.-H. | N/A | Complimentary vertebrate Wac models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome | |
| 低覆盖度测序的法医学似然比 | Ouerghi, F. | N/A | On forensic likelihood ratios from low-coverage sequencing | |
| 脂质组学和代谢组学插补（ImpLiMet）：用于缺失数据插补优化和方法选择的在线应用 | Ou, H. | N/A | Imputation for Lipidomics and Metabolomics (ImpLiMet): Online application for optimization and method selection for missing data imputation | |
| MLL4调控出生后腭部生长和中腭缝发育 | Lee, J.-M. | N/A | MLL4 regulates postnatal palate growth and midpalatal suture development | |
| 西尼罗病毒感染期间尖音库蚊中肠的单细胞图谱 | Fitzmeyer, E. A. | N/A | A single-cell atlas of the Culex tarsalis midgut during West Nile virus infection | |
| 调节前额叶皮层活动以缓解压力引起的工作记忆缺陷：一项经颅直流电刺激（tDCS）研究 | Roy, S. | N/A | Modulating Prefrontal Cortex Activity to Alleviate Stress-Induced Working Memory Deficits: A Transcranial Direct Current (tDCS) Study | |
| 植物细胞壁的纤维网络性质能够为发育提供可调的力学性能 | Chen, S. | N/A | Fibrous Network Nature of Plant Cell Walls Enables Tunable Mechanics for Development | |
| 生物医学数据的AI准备性：Bridge2AI建议 | Clark, T. | N/A | AI-readiness for Biomedical Data: Bridge2AI Recommendations | |
| 使用CryFold改进冷冻电镜图的自动化模型构建 | Su, B. | N/A | Improved automated model building for cryo-EM maps using CryFold | |
| 层粘连蛋白β4对于人类外周感觉神经元的发育是必需的。 | Saito-Diaz, K. | N/A | Laminin β4 is required for the development of human peripheral sensory neurons | |
| 从单细胞数据中映射增强子-基因调控相互作用 | Sheth, M. U. | N/A | Mapping enhancer-gene regulatory interactions from single-cell data | |
| 大肠杆菌细胞宽度稳态和膨胀动力学的力学机制：MreB和隔膜抑制的影响 | Kale, T. | N/A | Mechanics of E. coli cell width homeostasis and bulging dynamics from MreB and septum inhibition | |
| 使用常微分方程测量分裂酵母细胞中的调控网络继承 | Wu, W. | N/A | Measuring regulatory network inheritance in dividing yeast cells using ordinary differential equations | |
| 荧光蛋白标记的阴暗面：蛋白质标签对生物分子凝聚的影响 | Fatti, E. | N/A | The dark side of fluorescent protein tagging: the impact ofprotein tags on biomolecular condensation | |
| 肌醇需求酶1途径和自噬驱动内皮细胞对发热范围高热的顺序应答 | Vorbe, J. | N/A | Inositol-Requiring Enzyme 1 Pathway and Autophagy Drive Sequential Response of Endothelial Cells to Febrile Range Hyperthermia | |
| 耐寒蟋蟀在脂肪体组织中强化其肌动蛋白细胞骨架 | van Oirschot, M. L. | N/A | Freeze-tolerant crickets fortify their actin cytoskeleton in fat body tissue | |
| 缩小规模以提高效率：用于蛋白质序列迁移学习的中型Transformer模型 | Vieira, L. C. | N/A | Scaling Down for Efficiency: Medium-Sized Transformer Models for Protein Sequence Transfer Learning | |
| 利用优化的SIBR-Cas系统在Cupriavidus necator H16中实现简化和高效的基因组编辑 | Della Valle, S. | N/A | Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system | |
| 通过广泛调查外壳成分，推进细菌孢子上的蛋白质展示 | Chappell, T. C. | N/A | Advancing protein display on bacterial spores through an extensive survey of coat components | |
| 全球神经元形状推理与点亲和变压器 | Troidl, J. | N/A | Global Neuron Shape Reasoning with Point Affinity Transformers | |
| 视觉言语通过不同的机制增强听觉起始时间和包络追踪 | Cao, C. Z. | N/A | Visual speech enhances auditory onset timing and envelope tracking through distinct mechanisms | |
| 在脑刺激反应波动中分离三种变异性和噪声来源 | Ma, K. | N/A | Separating three variability and noise sources in the response fluctuation of brain stimulation | |
| 热应激通过促进弧菌科（Vibrionaceae）的生长，影响了大西洋鲑鱼的肠道微生物群，并伴随着大量黏液的产生。 | Bowman, J. P. | N/A | Heat stress impacts the gut microbiome of Atlantic salmon by promoting growth of Vibrionaceae and is associated with extensive cast production | |
| 具有两种不同DNA结合模式的保守ComP结构——使用AlphaFold3、RoseTTAFold2NA、Chai-1进行系统建模及在HADDOCK中重新对接 | Helsem, S. | N/A | The conserved ComP structure with two distinct DNA binding modes - systematic modeling with AlphaFold3, RoseTTAFold2NA, Chai-1 and re-docking in HADDOCK | |
| 普雷沃氏菌属copri与代谢功能障碍相关脂肪性肝病进展中的肝纤维化进展之间的关联 | Leitman, M. | N/A | The Association Between Prevotella copri and Advanced Fibrosis in the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease | |
| 细菌性枯萎病对高良姜可培养内生真菌群落组成和多样性的影响 | Wang, L. | N/A | Effects of Bacterial Wilt on Community Composition and Diversity of Culturable Endophytic Fungi in Alpinia galanga | |
| 双BONCAT揭示了盐沼沉积物中昼夜活跃的微生物群落的差异 | Maierhaba, Y. | N/A | Dual-BONCAT Reveals Distinct Day- and Night-Active Microbial Populations in Salt Marsh Sediments | |
| 多样的噬菌体防御系统定义了西非南美大流行霍乱弧菌 | Adams, D. W. | N/A | Diverse phage defence systems define West African South American pandemic Vibrio cholerae | |
| 亚马孙部落亚诺马米人的皮肤微生物群复杂性挑战了当前对健康皮肤的普遍概念。 | Durack, J. | N/A | Yanomami skin microbiome complexity challenges prevailing concepts of healthy skin. | |
| 一种由多种菌株组成、能够形成生物膜的枯草芽孢杆菌（Bacillus spp.）和片球菌属（Pediococcus spp.）混合物改变了聚乙烯犊牛舍表面的微生物组成。 | Reynolds, C. A. | N/A | A Multi-Strain, Biofilm-Forming Cocktail of Bacillus spp. and Pediococcus spp. Alters the Microbial Composition on Polyethylene Calf Housing Surfaces | |
| 接受抗CD49d和肌营养不良蛋白外显子跳跃吗啉代处理的mdx小鼠；力损失减少及基因表达通路改变支持ATL1102联合疗法在DMD患者中的应用。 | Padhye, A. S. | N/A | Mdx mice dosed with antisense to CD49d and dystrophin exon skip morpholino; reduced force loss and affected gene expression pathways support ATL1102 combination therapy in DMD patients | |
| 登革病毒蛋白酶介导的巨噬细胞激活与极化 | Misra, R. | N/A | Dengue Protease-Mediated Activation and Polarization of Macrophages | |
| 漆黄素在隐性营养不良性大疱性表皮松解症的小鼠模型中延长了寿命。 | Miller, W. C. | N/A | Fisetin extends lifespan in a murine model of recessive dystrophic epidermolysis bullosa | |
| 在出芽酵母中，UPR（未折叠蛋白反应）的缺陷揭示了内质网折叠能力与维持整倍体之间的权衡。 | Bartolutti, C. | N/A | UPR deficiency in budding yeast reveals a trade-off between ER folding capacity and maintenance of euploidy | |
| 功能性分裂tRNA：密码子解码机制的新视角 | Mureev, S. | N/A | Functional split-tRNA: a new perspective on codon decoding mechanism | |
| 一种偏好腺苷碱基编辑器，具有最小的旁观者效应和脱靶编辑 | Shang, M. | N/A | A motif preferred adenine base editor with minimal bystander and off-targets editing | |
| 寄生虫、宿主、猎物和环境之间的LINE-RTE逆转录转座子的水平转移。 | Brann, T. | N/A | Horizontal transfer of a LINE-RTE retrotransposon among parasite, host, prey and environment. | |
| 使用计数分割评估合成重复样本中的RNA速度稳定性 | Li, Y. | N/A | Assessing RNA velocity stability across syntheticreplicates using count splitting | |
| 哺乳动物进化过程中RNA修饰的保守景观与转录多样性 | Rodriguez, G. S. | N/A | The conserved landscape of RNA modifications and transcript diversity across mammalian evolution | |
| 非人灵长类动物在情境依赖性物体序列中的灵活学习和重新排序 | Wen, X. | N/A | Flexible Learning and Re-ordering of Context-dependent Object Sequences in Nonhuman Primates | |
| 3-硝氧基丙醇对荷斯坦牛和瑞士褐牛肠道甲烷排放的不同影响，及其与金合欢单宁提取物缺乏协同作用 | Islam, M. Z. | N/A | Divergent effects of 3-nitrooxypropanol on enteric methane emissions in Holstein and Brown Swiss cows, and its lack of synergy with Acacia mearnsii tannin extract | |
| TDP-43及其C端片段在体外增强的聚集，而非相分离，产生了深蓝色的自体荧光。 | Saravanan, P. | N/A | Enhanced in vitro aggregation, but not phase separation, of TDP-43 and its C-terminal fragments generate deep-blue autofluorescence. | |
| 金属感应传感器组氨酸激酶ZraS细胞质域构象动力学的洞察 | Mahapatra, N. | N/A | Insights into the conformational dynamics of the cytoplasmic domain of metal-sensing sensor histidine kinase ZraS | |
| 采血部位和血样基质影响矿物质评估 | Alejandro, M. G. | N/A | Blood draw site and blood matrix influence mineral assessment | |
| 使用BERT分词器建模引物-模板相互作用以通过注意力-BiLSTM预测PCR扩增 | Latifian, N. | N/A | Modeling Primer-Template Interactions using BERT Tokenizer to Predict PCR Amplification with Attention-BiLSTM | |
| MAT2a和AHCY抑制破坏抗氧化代谢并减少胶质母细胞瘤细胞存活 | Rowland, E. C. | N/A | MAT2a and AHCY Inhibition Disrupts Antioxidant Metabolism and Reduces Glioblastoma Cell Survival | |
| 单CAR-双靶点：抗PD-L1 CAR T细胞的颅内递送有效根除胶质瘤及肿瘤微环境中的免疫抑制细胞。 | Ulloa-Navas, M. J. | N/A | Single CAR-Dual target: Intracranial Delivery of Anti-PD-L1 CAR T Cells Effectively Eradicates Glioma and Immunosuppressive Cells in the Tumor Microenvironment. | |
| mTOR抑制减轻了tau蛋白磷酸化引起的线粒体功能障碍、氧化应激和认知功能障碍。 | Tang, Z. | N/A | mTOR inhibition alleviated tau phosphorylation-induced mitochondrial impairment, oxidative stress, and cognitive impairment | |
| 单神经元激活赋予了认知任务中涌现电路解决方案的归纳偏置 | Tolmachev, P. | N/A | Single-unit activations confer inductive biases for emergent circuit solutions to cognitive tasks | |
| 青少年三重网络动态及其未来饮酒行为 | McIntyre, C. C. | N/A | Triple network dynamics and future alcohol consumption in adolescents | |
| 阿尔茨海默病风险基因MS4A4A和MS4A6A协同作用，负向调控TREM2及小胶质细胞状态 | Rosner, D. | N/A | The Alzheimers Disease Risk Genes MS4A4A And MS4A6A Cooperate to Negatively Regulate Trem2 and Microglia states | |
| 控制二元和加权网络中的互惠性：一种新颖的密度保持方法 | Hadaeghi, F. | N/A | Controlling Reciprocity in Binary and Weighted Networks: A Novel Density-Conserving Approach | |
| 一项关于早期生活压力对前额叶皮层转录组影响的元分析表明，其具有长期影响髓鞘的作用。 | Duan, T. Q. | N/A | A meta-analysis of the effects of early life stress on the prefrontal cortex transcriptome suggests long-term effects on myelin | |
| 脑特征图揭示了在腹侧流中逐步形成的动物特征表征。 | Zhang, Z. | N/A | Brain Feature Maps Reveal Progressive Animal-Feature Representations in the Ventral Stream. | |
| 沙门氏菌对胆汁压力的抵抗力因抗氧化酶YqhD介导的排出泵活性降低而受损。 | Parmar, K. | N/A | The resilience of Salmonella to bile stress is impaired due to the reduced efflux pump activity mediated by the antioxidant enzyme YqhD | |
| 抗生素治疗和微生物群耗竭减缓刺胞动物再生 | Da-Anoy, J. | N/A | Antibiotic treatment and microbiome depletion slow cnidarian regeneration | |
| 大西洋鲑鱼养殖于温暖水域的胃肠道黏膜层细菌的特性研究 | Hall, K. | N/A | Characterization of bacteria colonizing the mucosal layer of the gastrointestinal tract of Atlantic salmon farmed in a warm water region | |
| X-信号元件sex-1在胚胎性别决定和剂量补偿中的多层次转录调控 | Jash, E. | N/A | Multi-level transcriptional regulation of embryonic sex determination and dosage compensation by the X-signal element sex-1 | |
| # BioRxiv 2024-11-23 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| NAVIP：揭示邻近小序列变异对功能影响预测的影响 | Baasner, J.-S. | N/A | NAVIP: Unraveling the Influence of Neighboring Small Sequence Variants on Functional Impact Prediction | |
| 评估临床前心血管研究中的研究设计严谨性：一项重复性研究 | Zahiri, K. | N/A | Evaluating Study Design Rigor in Preclinical Cardiovascular Research: A Replication Study | |
| 多发性骨髓瘤相关DIS3突变驱动AID依赖性IgH易位 | Kulinski, T. M. | N/A | Multiple Myeloma associated DIS3 mutations drive AID-dependent IgH Translocations | |
| RNAmigos2：基于结构的RNA虚拟筛选，结合半监督图学习和大规模对接数据，实现快速且准确的结果 | Carvajal-Patino, J. G. | N/A | RNAmigos2: Fast and accurate structure-based RNA virtual screening with semi-supervised graph learning and large-scale docking data | |
| 铜绿假单胞菌极性鞭毛组装的时空和数量调控 | Pulido-Sanchez, M. | N/A | Spatial, temporal and numerical regulation of polar flagella assembly in Pseudomonas putida | |
| 通过分子模拟探索Abeta42单体在纤维表面上的扩散动力学 | Ma, Y.-W. | N/A | Exploring Abeta42 Monomer Diffusion Dynamics on Fibril Surfaces through Molecular Simulations | |
| 在决策过程中，无论是提升还是降低决策质量，噪音的来源 | Shen, B. | N/A | Origins of noise in both improving and degrading decision making | |
| 威胁处理过程中的大脑动态与时空轨迹 | Misra, J. | N/A | Brain dynamics and spatiotemporal trajectories during threat processing | |
| 各向异性水凝胶降解增强三维集体细胞排列、力传导和成骨分化 | Garrido, C. A. | N/A | Anisotropic Hydrogel Degradation Enhances 3D Collective Cell Alignment, Mechanotransduction and Osteogenic Differentiation | |
| 通过多模态堆叠提高认知能力的全脑关联的可预测性、重测信度和普适性 | Tetereva, A. | N/A | Improving Predictability, Test-Retest Reliability and Generalisability of Brain-Wide Associations for Cognitive Abilities via Multimodal Stacking | |
| ErbB2/HER2通过调节c-Myc和cyclin D的功能，调控CDK4抑制剂的敏感性、G1/S期转换的时机和不可逆性。 | Ichikawa, A. N. | N/A | ErbB2/HER2 governs CDK4 inhibitor sensitivity and timing and irreversibility of G1/S transition by altering c-Myc and cyclin D function | |
| 基于全脑成像的细胞c-Fos表达的迷幻药和精神活性药物分类 | Aboharb, F. | N/A | Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression | |
| 一种开花时间可塑性的反应规范揭示了玉米适应的生理足迹 | Drouault, J. | N/A | A reaction norm for flowering time plasticity reveals physiological footprints of maize adaptation | |
| 鼻内给予丹曲林纳米颗粒抑制脂多糖诱导的小鼠抑郁和焦虑行为 | Liu, J. | N/A | Intranasal dantrolene nanoparticles inhibit lipopolysaccharide-induced depression and anxiety behavior in mice | |
| 结合转录组学、连接性和活性分析，利用高度放大的多重原位杂交技术（hamFISH）对内侧杏仁核进行研究 | Edwards, M. D. | N/A | Combined transcriptomic, connectivity, and activity profiling of the medial amygdala using highly amplified multiplexed in situ hybridization (hamFISH) | |
| 基于聚丙烯酰胺的抗菌共聚物：替代或拯救抗生素 | Williams, S. C. | N/A | Polyacrylamide-based Antimicrobial Copolymers to Replace or Rescue Antibiotics | |
| 室温下绿色荧光蛋白的气溶胶脱水 | Pan, Z. | N/A | Room-Temperature Aerosol Dehydration of Green Fluorescent Protein | |
| LIET模型：从加载到终止，捕捉RNA聚合酶的动力学过程 | Stanley, J. T. | N/A | LIET Model: Capturing the kinetics of RNA polymerase from loading to termination | |
| 利用鸡胚绒毛尿囊膜模型评估肿瘤定植沙门氏菌株 | Mon, K. K. Z. | N/A | Evaluation of Tumor-colonizing Salmonella Strains using the Chick Chorioallantoic Membrane Model | |
| 单剂量禽流感A(H5N1)谱系2.3.4.4b血凝素-基质-M纳米颗粒疫苗在非人灵长类动物中诱导了中和反应 | Patel, N. | N/A | Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin-Matrix-M nanoparticle vaccine induces neutralizing responses in nonhuman primates | |
| PyEvoCell：一个增强型大型语言模型单细胞轨迹分析仪表板 | Mathur, S. | N/A | PyEvoCell: An LLM- Augmented Single Cell Trajectory Analysis Dashboard | |
| 研究光系统II中TyrD、TyrZ和QA*-形成引起的Soret区域电致变色带移 | Boussac, A. | N/A | Investigation of electrochromic band-shifts in the Soret region induced by the formation of TyrD, TyrZ, and QA*- in Photosystem II | |
| 一种参考基因组：Trichogramma kaykai，一种生活在沙漠中的小型寄生蜂，具有竞争性的性比破坏者 | Culotta, J. | N/A | A reference genome for Trichogramma kaykai: A tiny desert-dwelling parasitoid wasp with competing sex-ratio distorters | |
| 使用TubeTracker进行半自动高内涵花粉性能分析 | Yimga Ouonkap, S. V. | N/A | Semi-automated High Content Analysis of Pollen Performance Using TubeTracker | |
| 人脑中的大规模信号传播模式 | Song, Y. | N/A | Large-scale Signal Propagation Modes in the Human Brain | |
| 药物抑制SUMOylation在小鼠附睾白色脂肪组织中再现了遗传性低SUMOylation | Dufour, D. | N/A | Pharmacological inhibition of SUMOylation recapitulates genetic hypoSUMOylation in the murine epididymal white adipose tissue | |
| 六足束缚：一种新描述的昆虫步态 | Amir, A. | N/A | Six-legged-bound: a newly-described insect gait | |
| 硬骨鱼类不同的视觉运动策略：斑马鱼和小头鱼脑中的神经回路机制 | Fouke, K. E. | N/A | Divergent Visuomotor Strategies in Teleosts: Neural Circuit Mechanisms in Zebrafish and Danionella cerebrum | |
| 皮质生物混合植入物的光遗传学刺激指导目标导向行为 | Brown, J. | N/A | Optogenetic stimulation of a cortical biohybrid implant guides goal directed behavior | |
| 任务诱发的内部身体状态而非大脑状态调节人类自我感知 | Xie, M. | N/A | Task-induced internal bodily rather than brain states regulate human self-perception | |
| 神经支配密度调控基于GPCR的去甲肾上腺素和多巴胺传感器的交叉干扰 | Lopez, R. C. | N/A | Innervation density governs crosstalk of GPCR-based norepinephrine and dopamine sensors | |
| 对家族性阿尔茨海默病生物标志物研究中的五种淀粉样β肽进行无偏差的数据驱动分析 | Llorente-Saguer, I. | N/A | Unbiased data-driven analysis of five amyloid-beta peptides for biomarker investigations in familial Alzheimer's disease | |
| 神经肽受体转录调控解析肽能调节行为与生理的复杂性。 | Ryu, S. | N/A | Transcriptional Regulation of Neuropeptide Receptors Decodes Complexity of Peptidergic Modulation of Behavior and Physiology. | |
| SARS-CoV-2在源自人类诱导多能干细胞（hiPSC）的神经元中的感染依赖于组织蛋白酶，并导致HIF1α和磷酸化tau的积累。 | Kettunen, P. | N/A | SARS-CoV-2 infection in hiPSC-derived neurons is cathepsin-dependent and causes accumulation of HIF1alpha and phosphorylated tau | |
| 直接从临床拭子中测序沙眼衣原体和其他细菌性性传播感染基因组的挑战：最佳解决方案 | Buttner, K. A. | N/A | The challenge of sequencing Chlamydia trachomatis and other bacterial STI genomes directly from clinical swabs: the optimum solution | |
| 环境灾难期间多倍体现象的兴起 | Chen, H. | N/A | The Rise of Polyploids During Environmental Catastrophes | |
| UniversalEPI：利用注意力机制解码稀有和未探索细胞类型中的染色质相互作用 | Grover, A. | N/A | UniversalEPI: Harnessing Attention Mechanisms to Decode Chromatin Interactions in Rare and Unexplored Cell Types | |
| 重新编程M13噬菌体基因组，用于一体化个性化癌症疫苗 | Huang, S. | N/A | Reprogramming the genome of M13 bacteriophage for all-in-one personalized cancer vaccine | |
| 用于从单细胞RNA测序数据中进行无监督细胞聚类的新算法 | Robles, M. | N/A | New algorithms for unsupervised cell clusteringfrom scRNA-seq data | |
| 通过组合式池化实现稳健且成本效益高的单细胞测序 | Gawron, J. | N/A | Robust and cost-efficient single-cell sequencing through combinatorial pooling | |
| CNV-Finder：简化拷贝数变异发现流程 | Kuznetsov, N. | N/A | CNV-Finder: Streamlining Copy Number Variation Discovery | |
| 在组织病理学中使用统一扩散框架进行多功能的污渍转移 | Yan, X. | N/A | Versatile Stain Transfer in Histopathology Using a Unified Diffusion Framework | |
| 由突变NEK1聚集驱动的肌萎缩侧索硬化症（ALS）在Pml丢失的情况下会加速发展，但通过药物诱导Pml介导的降解可以临床上逆转这一过程。 | Georgiadou, P. | N/A | ALS driven by mutant NEK1 aggregation is accelerated by Pml loss, but clinically reversed through pharmacologic induction of Pml-mediated degradation | |
| 克罗恩病中持续炎症上皮祖细胞状态的表观遗传基础 | Karakasheva, T. A. | N/A | An epigenetic basis for sustained inflammatory epithelial progenitor cell states in Crohn's disease | |
| 通过高效招募mRNA到合成细胞膜上实现膜蛋白的原位表达 | Fu, H. | N/A | In situ Membrane Protein Expression by Efficient Recruitment of mRNA to the Membranes of Synthetic Cells | |
| 在系统性幼年特发性关节炎中发生的药物相关性肺泡蛋白沉积症期间，表达IFNγ的髓系细胞定位于脂蛋白沉积物中。 | Delmastro, A. | N/A | IFNγ-Expressing Myeloid Cells Localize within Lipoproteinosis during Drug-Associated Pulmonary Alveolar Proteinosis occurring in Systemic Juvenile Idiopathic Arthritis | |
| 热休克因子2通过重塑染色质景观正向调控致癌性疱疹病毒基因表达 | Cutrone, L. | N/A | Heat shock factor 2 positively regulates oncogenic herpesvirus gene expression by remodeling the chromatin landscape | |
| 感染疫霉菌的诺维病毒能够减弱其营养生长，促进孢子囊形成，并赋予宿主卵菌超强毒力。 | Sakuta, K. | N/A | Novel endornaviruses infecting Phytophthora cactorum that attenuate vegetative growth, promote sporangia formation, and confer hypervirulence to the host oomycete. | |
| 来自直肠样本的沙眼衣原体基因组：描述包含阿根廷ompA基因型L4的新分支 | Buttner, K. A. | N/A | Chlamydia trachomatis genomes from rectal samples: description of new clade comprising ompA-genotype L4 from Argentina | |
| 通过多搜索引擎和重新评分最大化基于免疫肽组学的细菌表位发现 | Willems, P. | N/A | Maximizing immunopeptidomics-based bacterial epitope discovery by multiple search engines and rescoring | |
| 从泰国斑鸠粪便中分离出的酵母Hyphopichia burtonii的全基因组测序 | Ngasaman, R. | N/A | Whole-genome sequencing of Hyphopichia burtonii from isolated yeast recovered from zebra dove droppings in Thailand | |
| 成对相互作用和连续瓶颈效应有助于解释多物种微生物群落的物种组成 | Lele, K. | N/A | Pairwise interactions and serial bottlenecks help explain species composition in a multi-species microbial community | |
| 介绍SPROUT（使用阈值处理的半自动化区域分割输出）：一种可适应的计算机视觉工具，用于生成3D分割 | He, Y. | N/A | Introducing SPROUT (Semi-automated Parcellation of Region Outputs Using Thresholding): an adaptable computer vision tool to generate 3D segmentations | |
| 精氨酰转移酶1驱动一个依赖线粒体的程序以诱导细胞死亡 | Kumar, A. | N/A | Arginyltransferase1 drives a mitochondria-dependent program to induce cell death | |
| 如何预测有效的药物组合 - 超越协同评分 | Eckhart, L. | N/A | How to Predict Effective Drug Combinations - Moving beyond Synergy Scores | |
| VIACOT：一个用于交互式可视化和比较细胞谱系树的网络服务器 | Yang, J. | N/A | VIACOT: a web server for interactive visualization and comparison of cell lineage trees | |
| 利用人类泛基因组资源描述人类可变转座子插入的胞嘧啶甲基化 | Zhuo, X. | N/A | Characterizing cytosine methylation of polymorphic human transposable element insertions using human pangenome resources | |
| TMVisDB：一种用于跨膜蛋白注释和三维可视化的资源 | Olenyi, T. | N/A | TMVisDB: A Resource for Transmembrane Protein Annotations and 3D Visualizations | |
| 通过局部活动和全局敏感化实现受体极化 | Goetz, A. | N/A | Receptor polarization through localized activity and global sensitization | |
| 机械应力调控肌细胞融合与肌管生长 | Le Toquin, Y. | N/A | Mechanical stresses govern myoblast fusion and myotube growth | |
| 本地高蛋白、植物基即用型治疗食品增强了大鼠的消瘦恢复能力 | Bechoff, A. | N/A | Local High-Protein, Plant-Based Ready-to-Use Therapeutic Food Enhances Recovery from Malnutrition in Rats | |
| Shroom3-Rock相互作用及促纤维化功能：解析内含子CKD风险等位基因的机制。 | Reghuvaran, A. C. | N/A | Shroom3-Rock interaction and profibrotic function: Resolving mechanism of an intronic CKD risk allele. | |
| 哥斯达黎加野生树懒的胃肠道寄生虫宿主特异性 | Vanderheoven, E. | N/A | Host specificity of gastrointestinal parasites in free-ranging sloths from Costa Rica | |
| 社会隔离降低了野生型斑马鱼（Danio rerio）的代谢率和社交偏好 | Ghosh, A. | N/A | Social isolation reduces metabolic rate and social preference in Wild-type Zebrafish (Danio rerio) | |
| 基于结构的共价纳米抗体结合剂设计用于热稳定绿色荧光蛋白 | Yue, Z. | N/A | Structure-Based Design of Covalent Nanobody Binders for a Thermostable Green Fluorescence Protein | |
| # BioRxiv 2024-11-22 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 脑岛和颞上沟在社会决策中对人际内疚和责任感的贡献 | Gaedeke, M. | N/A | Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions | |
| 在向极地范围扩展过程中，生态和进化的快速分化 | Sheffer, M. M. | N/A | Rapid ecological and evolutionary divergence during a poleward range expansion | |
| GraphComm：一种基于图的深度学习方法，用于预测单细胞RNAseq数据中的细胞间通讯 | So, E. | N/A | GraphComm: A Graph-based Deep Learning Method to Predict Cell-Cell Communication in single-cell RNAseq data | |
| 设计可靠且准确的表观遗传时钟：选择最佳的计算解决方案 | Vavourakis, C. D. | N/A | Devising reliable and accurate epigenetic clocks: choosing the optimal computational solution | |
| 跨越解剖长度尺度和物种的3D白质通路几何组织桥梁 | Kjer, M. | N/A | Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species | |
| Galectin-9通过调节RhoA活性来调控树突状细胞的极性和尾足收缩。 | Franken, G. | N/A | Galectin-9 regulates dendritic cell polarity and uropod contraction by modulating RhoA activity | |
| WhatIsMyGene：回归基因富集的基本原理 | Hodge, K. G. | N/A | WhatIsMyGene: Back to the Basics of Gene Enrichment | |
| WhatIsMyGene：回归基因富集的基本原理 | Hodge, K. G. | N/A | WhatIsMyGene: Back to the Basics of Gene Enrichment | |
| 血红素的相关性真实吗？重新审视包括HRG-9和HRG-10在内的TANGO2同源基因在秀丽隐杆线虫中的作用 | Sandkuhler, S. E. | N/A | Heme's relevance genuine? Re-visiting the roles of TANGO2 homologs including HRG-9 and HRG-10 in C. elegans | |
| 使用概率主题建模估计全基因组系统发育树 | Khodaei, M. | N/A | Estimating Genome-wide Phylogenies Using Probabilistic Topic Modeling | |
| 用微藻替代饲料中的鱼油对金头鲷中肠细菌微生物群的影响 | Katsoulis-Dimitriou, S. | N/A | The effect of dietary fish oil replacement by microalgae on the gilthead sea bream midgut bacterial microbiota | |
| 通过致癌假激酶PEAK1对CAMK2的前馈刺激，在三阴性乳腺癌中生成了一种具有治疗潜力的信号轴。 | Yang, X. | N/A | Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically "actionable" signalling axis in triple negative breast cancer | |
| CMTM6通过维持B细胞内在的CD40表达，以调节抗肿瘤免疫。 | Long, Y. | N/A | CMTM6 maintains B cell intrinsic CD40 expression to regulate anti-tumor immunity | |
| 使用深度强化学习进行果蝇真实运动的全身体模拟 | Vaxenburg, R. | N/A | Whole-body simulation of realistic fruit fly locomotion with deep reinforcement learning | |
| 进化上较新的人类基因的功能关联对三维基因组景观和疾病具有敏感性。 | Fleck, K. | N/A | Functional associations of evolutionarily recent human genes exhibit sensitivity to the 3D genome landscape and disease | |
| 研究睡眠期间大脑活动的时序动态及其成熟过程：早产儿与足月婴儿的脑电微状态研究。 | Adibpour, P. | N/A | Characterizing the temporal dynamics and maturation of brain activity during sleep: an EEG microstate study in preterm and full-term infants. | |
| 肝毒性和胆汁淤积性肝纤维化模型中隔室特异性蛋白质组景观的动态变化 | Jirouskova, M. | N/A | Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis | |
| 一种用于阿根廷蚂蚁食物偏好实验的高通量且灵敏的方法 | Wagner, T. | N/A | A high-throughput and sensitive method for food preference assays in the Argentine ant | |
| 异种线粒体移植可减轻心脏骤停后的心肌功能障碍 | Wang, Z. | N/A | Transplantation of exogenous mitochondria mitigates myocardial dysfunction after cardiac arrest | |
| 基因灭活β1肾上腺素受体可防止斑马鱼脑部海绵状血管畸形 | Li, W. | N/A | Genetic Inactivation of the beta1 adrenergic receptor prevents Cerebral Cavernous Malformations in zebrafish | |
| 自由移动的狨猴使用头戴式眼动追踪进行主动视觉 | Singh, V. P. | N/A | Active vision in freely moving marmosets using head-mounted eye tracking | |
| 早期视觉皮层和面部选择性脑区中空间选择性的常见模式 | Morsi, A. Y. | N/A | Common patterns of spatial selectivity in early visual cortex and face-selective brain regions | |
| 早期肠道炎症驱动了微生物组-内分泌-大脑轴的性别依赖性转变 | Sullivan, O. | N/A | Early-Life Gut Inflammation Drives Sex-Dependent Shifts in the Microbiome-Endocrine-Brain Axis | |
| 通过通信理论研究时间分辨的功能连接：相位同步与滑动窗口皮尔逊相关之间的互补性。 | Wiafe, S.-L. | N/A | Studying time-resolved functional connectivity via communication theory: on the complementary nature of phase synchronization and sliding window Pearson correlation. | |
| 成人颞叶新皮质第1层中兴奋性突触小体的超微结构亚层特异性多样性 | Rollenhagen, A. | N/A | Ultrastructural sublaminar-specific diversity of excitatory synaptic boutons in layer 1 of the adult human temporal lobe neocortex | |
| 在时间决策中发起追求的价值 | Sutlief, E. | N/A | The value of initiating a pursuit in temporal decision-making | |
| CD28通过调节ZAP70激活和Lck动力学来塑造T细胞受体信号传导 | Raychaudhuri, K. | N/A | CD28 Shapes T Cell Receptor Signaling by Regulating ZAP70 Activation and Lck Dynamics | |
| 通过单轮成像实现三维组织中的彩色条码超多重RNA荧光原位杂交 | Chang, T. | N/A | Color-barcoded Super-multiplex RNA FISH in Three-dimensional Tissues through Single-round Imaging | |
| 新型长链非编码RNA——CyKILR的RNA剪接变体在非小细胞肺癌中具有不同的生物学功能 | Xie, X. | N/A | RNA splicing variants of the novel long non-coding RNA, CyKILR, possess divergent biological functions in non-small cell lung cancer | |
| KLF6在肺动脉高压中的双重角色：既是朋友也是敌人 | Alharbi, R. | N/A | KLF6 in Pulmonary Hypertension: The Dual Role of Friend and Foe | |
| 地中海地区开放植被火灾中气候变化物种的排放——方法和数据的综述 | Hundal, R. A. | N/A | Emissions of climate-altering species from open vegetation fires in the Mediterranean region - A review on methods and data | |
| 细胞类型特异的表观遗传时钟，用于在细胞类型分辨率上量化生物年龄 | Tong, H. | N/A | Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution | |
| IFITM3的CD225结构域通过模拟SNARE实现对同型晚期内体融合的调控 | Rahman, K. | N/A | SNARE mimicry by the CD225 domain of IFITM3 enables regulation of homotypic late endosome fusion | |
| 一种用于精确递送蛋白质、核酸和治疗药物的模块化封装系统 | Luong, T. D. | N/A | A modular encapsulation system for precision delivery of proteins, nucleic acids and therapeutics | |
| 一种灵活的高精度光声视网膜假体 | Leong, A. | N/A | A flexible high-precision photoacoustic retinal prosthesis | |
| 光系统II释放氧气后，能够进展到S1状态的S0状态的重组动力学 | Boussac, A. | N/A | Kinetics of reformation of an S0 state capable of progressing to an S1 state after the O2 release by Photosystem II | |
| 磷酸化诱导的SUMO化促进了Ulk4在纤毛尖端的凝聚，以传导Hedgehog信号 | Zhou, M. | N/A | Phosphorylation-induced SUMOylation promotes Ulk4 condensation at ciliary tip to transduce Hedgehog signal | |
| 从诱导多能干细胞发展调控内皮向造血转变 | Wellington, R. | N/A | Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells | |
| 对Synechocystis 6803和Thermosynechococcus vestitus中光系统II功能中残基D1/V185作用的新见解。 | Boussac, A. | N/A | New insights into the involvement of residue D1/V185 in Photosystem II function in Synechocystis 6803 and Thermosynechococcus vestitus. | |
| 细胞周期蛋白A和细胞周期蛋白B的mRNA转录后调控由Bruno 1和Cup介导，并在P-bodies内进一步微调。 | Bayer, L. V. | N/A | Post-transcriptional regulation of cyclin A and cyclin B mRNAs is mediated by Bruno 1 and Cup, and further fine-tuned within P-bodies | |
| 基于代理的拟南芥合子中皮层微管带运动模拟 | Nonoyama, T. | N/A | Agent-Based Simulation of Cortical Microtubule Band Movement in the Arabidopsis Zygote | |
| 先验的相关性如何？贝叶斯因果推断在易变环境中的动态感知 | Meijer, D. | N/A | How relevant is the prior? Bayesian causal inference for dynamic perception in volatile environments | |
| Ccp1的耗竭破坏了海马区小清蛋白中间神经元的网络整合 | Le Bail, R. | N/A | Ccp1 depletion disrupts network integration of hippocampal parvalbumin interneurons | |
| CelLink：整合单细胞多组学数据，处理弱特征关联与细胞群体不平衡问题 | Luo, X. | N/A | CelLink: integrating single-cell multi-omics data with weak feature linkage and imbalanced cell populations | |
| 工作记忆中感觉和运动内容的动态优先级排序 | Echeverria-Altuna, I. | N/A | Dynamic prioritisation of sensory and motor contents in working memory | |
| 单个神经元对特定模态和非模态语言的处理 | Lakretz, Y. | N/A | Modality-Specific and Amodal Language Processing by Single Neurons | |
| 靶向激活小胶质细胞PPARδ可重编程免疫代谢，并增强饮食诱导肥胖中的胰岛素敏感性。 | Jiao, H. | N/A | Targeted activation of microglial PPARdelta reprograms immunometabolism and enhances insulin sensitivity in diet-induced obesity. | |
| 面向多模态纵向分析以预测认知衰退 | Ashish, R. M. | N/A | Towards Multimodal Longitudinal Analysis for Predicting Cognitive Decline | |
| 伊维菌素残留对粪生昆虫的背景依赖性影响：与环境压力源、体型和性别在一种腐蝇（Sepsis neocynipsea）中的相互作用 | Walker, J. | N/A | Context-dependent effects of ivermectin residues on dung insects: Interactions with environmental stressors, size, and sex in a sepsid fly (Sepsis neocynipsea) | |
| 昆虫肠道中的免疫启动：通过超微结构和转录组变化揭示的动态反应 | Baur, M. | N/A | Immune priming in the insect gut: a dynamic response revealed by ultrastructural and transcriptomic changes | |
| 破伤风类毒素通过靶向肿瘤唾液酸和增强细胞毒性CD4+ T细胞对胰腺癌的反应，利用双面抗癌机制 | Giurini, E. | N/A | Tetanus Toxoid Utilizes Dual-Faceted Anticancer Mechanism Through Targeting Tumoral Sialic Acids and Enhancing Cytotoxic CD4+ T cell Responses Against Pancreatic Cancer | |
| 淀粉体对于地钱（Marchantia polymorpha）叶状体的完全向地性是必要的。 | Hashimoto-Sugimoto, M. | N/A | Amyloplasts are necessary for full gravitropism in thallus of Marchantia polymorpha | |
| 古埃及前王朝时期考古遗存中高δ15N值：极端条件下局部土壤施肥实践的潜在指标 | Poulallion, E. | N/A | High δ15N values in Predynastic Egyptian archeological remains: A potential indicator for localised soil fertilisation practices in extreme conditions | |
| 以环丙沙星作为唯一碳源和能量来源，并展现出向可培养纳米级细菌的显著转变，由医院废水分离的克雷伯氏菌属SG01株所展示。 | Chakraborty, R. | N/A | Consumption of Ciprofloxacin as the sole Carbon and energy source and Phenomenal Transformation to a Culturable nanometer-sized- bacterium demonstrated by a hospital-waste-water isolate Klebsiella  sp. SG01 | |
| 硝酸铅对人类角质形成细胞（HaCaT）的毒性作用。 | Mohamed, A. | N/A | The toxic effects of lead nitrate on human keratinocytes (HaCaT). | |
| 鉴定和表征类衣原体细菌Simkania negevensis的泛素E3 RING连接酶 | Hörner, E.-M. | N/A | Identification and characterization of a ubiquitin E3 RING ligase of the Chlamydia-like bacterium Simkania negevensis | |
| NEMF通过阻断PI3K/mTOR通路抑制卵巢癌细胞的增殖和迁移。 | Wang, Q. | N/A | NEMF inhibits proliferation and migration of ovarian cancer cells by blocking the PI3K/mTOR pathway | |
| R-Spondin模拟物，SZN-043，诱导增殖和Wnt活性，这两个特征在人类酒精相关性肝病中缺失 | Fisher, T. | N/A | R-Spondin Mimetic, SZN-043, Induced Proliferation and Wnt Activity, Two Features Deficient in Human Alcohol-Associated Liver Disease | |
| MCC：应用于结核分枝杆菌的基因组规模自动化质量和电荷校正 | Mostolizadeh, R. | N/A | MCC: Automated Mass and Charge Curation at Genome-Scale Applied to C. tuberculostearicum | |
| 言语运动皮层使BCI光标控制和点击成为可能 | Singer-Clark, T. | N/A | Speech motor cortex enables BCI cursor control and click | |
| 言语运动皮层使BCI光标控制和点击成为可能。 | Singer-Clark, T. | N/A | Speech motor cortex enables BCI cursor control and click | |
| 血浆中失调蛋白质区分综合征性与非综合征性遗传性胸主动脉疾病 | Seim, B. E. | N/A | Dysregulated Proteins in Plasma Distinguishing Syndromic from Non-syndromic Heritable Thoracic Aortic Disease | |
| 抗真菌药物5-氟胞嘧啶是尿道致病性大肠杆菌的毒力抑制剂，并能与β-内酰胺类药物协同作用，根除生物膜嵌入的细菌。 | Ravishankar, S. | N/A | The antimycotic 5-fluorocytosine is a virulence inhibitor of uropathogenic Escherichia coli and eradicates biofilm-embedded bacteria synergizing with β-lactams | |
| 了解纤维素分解厌氧菌C. thermocellum对生物质解构的动态过程 | Yarbrough, J. | N/A | Understanding the Dynamics of Biomass Deconstruction by the Cellulolytic Anaerobe C. thermocellum | |
| 由温度传感器HktS-HktR介导的丁香假单胞菌猕猴桃致病变种的毒力和运动性 | Xiao, Y. | N/A | The virulence and motility of Pseudomonas syringae pv. Actinidiae mediated by a temperature sensor HktS-HktR | |
| StratPal：一个用于创建地层古生物学建模管道的R包 | Hohmann, N. | N/A | StratPal: An R package for creating stratigraphic paleobiology modeling pipelines | |
| Lewy-MSA混合折叠驱动独特的神经元a-突触核蛋白病理 | Enomoto, M. | N/A | Lewy-MSA hybrid fold drives distinct neuronal a-synuclein pathology | |
| 通过整合作物生长模型与全基因组预测，预测玉米杂交种子生产中自交系亲本在开花期的同步性 | Laurent, A. | N/A | Predicting inbred parent synchrony at flowering for maize hybrid seed production by integrating crop growth model with whole genome prediction | |
| 先进鞋类技术训练8周后的足部特异性生物力学和能量反应 | Matties, J. R. | N/A | Footwear-specific biomechanical and energetic responses to 8 weeks of training in advanced footwear technology | |
| 评估新西兰素食者的蛋白质摄入量和蛋白质质量 | Soh, B. X. P. | N/A | Evaluation of protein intake and protein quality in New Zealand vegans | |
| 刺激位于尾侧额上回的额斜束起始部，会独立于效应器改变正在进行中的自发节律性活动。此结论基于纤维束成像引导下的经颅磁刺激实验证据。 | Tagliaferri, M. | N/A | Stimulation of the Frontal Aslant Tract's origin in the caudal superior frontal gyrus alters ongoing spontaneous rhythmic activity independently from the effector. Evidence from tractography-guided Transcranial Magnetic Stimulation. | |
| 建模前生物起源的调控与代理在演化原细胞生态系统中的作用 | Shirt-Ediss, B. | N/A | Modelling the prebiotic origins of regulation & agency in evolving protocell ecologies | |
| 建模新宿主中的山松甲虫丰度 | Xie, X. | N/A | Modeling Mountain Pine Beetle Abundance in Novel Hosts | |
| 外周单核细胞中与祖先特异性基因表达相关的风险因素与神经退行性疾病的发生有关。 | Wagen, A. Z. | N/A | Ancestry-specific gene expression in peripheral monocytes mediates risk of neurodegenerative disease | |
| 双酚A及六种数据不足的类似物的人体内暴露量通过多模式参数化的生理学基础动力学模型预测 | Bigonne, H. | N/A | Human internal exposures of bisphenol A and six data-poor analogues predicted by physiologically based kinetic models with multimodal parameterization | |
| 左室致密化不全心肌病小鼠模型中的心脏电异常 | de la Pompa, J. L. | N/A | Cardiac electrical abnormalities in a mouse model of left ventricular non-compaction cardiomyopathy | |
| 植物化学成分及药理学评价：榕叶对氧化应激、镇痛、腹泻及小鼠模型中血液凝固的影响 | Labu, Z. K. | N/A | Phytochemical and Therapeutic Evaluation of Ficus nervosa Leaves: Impact on Oxidative Stress, Analgesic, Diarrhea, and Blood Clotting in a Mice Model | |
| 多巴胺与健康相关因素在脑认知差距中的作用：基于人工智能的功能连接组预测的见解 | Esmaeili, M. | N/A | Brain-Cognitive Gaps in relation to Dopamine and Health-related Factors: Insights from AI-Driven Functional Connectome Predictions | |
| 用于通过正电子发射断层扫描成像移植的一对同基因小鼠，使用抗转铁蛋白受体纳米抗体 | Balligand, T. | N/A | A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies | |
| 酵母菌喜欢托儿所，而霉菌则偏爱私人住宅。 | Kauserud, H. | N/A | Yeasts prefer daycares and molds prefer private homes | |
| 体外和体内研究针对克隆ST512的肺炎克雷伯菌临床菌株的噬菌体疗法医疗产品（PTMPs） | Bleriot, I. | N/A | Studies in vitro e in vivo of Phage Therapy Medical Products (PTMPs) targeting clinical strains of Klebsiella pneumoniae belonging to the clone ST512 | |
| 使用比较有限元分析测试颅骨功能假说：三种方法揭示了不同的结果 | Mitchell, D. R. | N/A | Testing hypotheses of skull function with comparative finite element analysis: three methods reveal contrasting results | |
| 神经生长因子和锌螯合剂的联合递送显著促进了视神经挤压模型中的轴突再生 | NGUYEN, H. Q. D. | N/A | Co-delivery of neurotrophic factors and a zinc chelator substantially promotes axon regeneration in the optic nerve crush model | |
| 一种网络正则化的线性模型，用于推断单细胞的空间表达模式 | Gu, C. | N/A | A network regularized linear model to infer spatial expression pattern for single cell | |
| 使用共振光散射技术观察皮摩尔级蛋白质的展开过程 | Alvarez, A. B. | N/A | Observing picomolar protein unfolding using resonance light scattering | |
| 微生物组蛋白质组分配揭示了饮食和代谢菌群失调如何影响疾病 | Tibocha-Bonilla, J. D. | N/A | Proteome allocation of the microbiome reveals how diet and metabolic dysbiosis impact disease | |
| 通过消除与病毒Fc受体gE/gI的相互作用，提高抗体介导的对HSV感染的保护作用 | Slein, M. D. | N/A | Improving antibody-mediated protection against HSV infection by eliminating interactions with the viral Fc receptor gE/gI | |
| 遗传筛选发现细胞壁酶是弗朗西斯菌属土拉热菌在淡水环境中生存的关键 | Macaraeg, A. | N/A | Genetic screen identifies cell wall enzyme is key for freshwater survival of Francisella tularensis | |
| rapgef1b在神经嵴特化及体节中胚层模式形成中的发育功能 | Prasad, T. | N/A | Developmental functions of rapgef1b in neural crest specification and presomitic mesoderm patterning | |
| 本科生研究项目在美国东北部发现了一种新型两栖动物壶菌 | Duryea, M. C. | N/A | Undergraduate research project uncovers a novel strain of amphibian chytrid fungus in the Northeastern United States | |
| 深海一次性鱿鱼种群的调控受表层水域的生态条件和深层鲸类捕食的影响。 | Rademaker, M. | N/A | Population regulation in semelparous deep-sea squid is driven by ecological conditions in surface waters and whale predation at depth | |
| 大型亚热带河流中野生鱼类肠道微生物的变量系统发育和共演化模式 | Liu, Y. | N/A | Variable phylosymbiosis and cophylogeny patterns in wild fish gut microbiota in a large subtropical river | |
| 家猫性连锁橙色毛色的分子和遗传特征 | Kaelin, C. B. | N/A | Molecular and genetic characterization of sex-linked orange coat color in the domestic cat | |
| PERCEPTIVE：一种用于预测新物种中表观遗传调控因子的R Shiny管道 | Small, E. M. | N/A | PERCEPTIVE: an R Shiny pipeline for the prediction of epigenetic modulators in novel species | |
| 一个用于结构解释DMS反应性的定量框架 | Deenalattha, S. | N/A | A quantitative framework for structural interpretation of DMS reactivity | |
| LYCHOS-mTORC1通路中胆固醇感应的结构见解 | Yu, S. | N/A | Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway | |
| 计算分析以评估降主动脉瘤中的血流动力学力 | Duca, F. | N/A | Computational analysis to assess hemodynamic forces in descending thoracic aortic aneurysms | |
| 高跟鞋穿着下过度肌肉协同收缩对坐立表现的影响 | Naik, G. | N/A | The Impact of Excessive Muscle Co-contraction on Sit-to-Stand Performance in High-Heeled Footwear | |
| 组织工程中的可解释人工智能：使用XGBoost和SHAP评估PLGA支架的生物相容性 | Rafat, M. T. | N/A | Interpretable AI in Tissue Engineering: XGBoost and SHAP for PLGA Scaffold Biocompatibility | |
| 步骤：利用全转录组覆盖解码单细胞水平的空间图谱 | Hu, Z. | N/A | STEP: Deciphering Spatial Atlas at Single-Cell Level with Whole-Transcriptome Coverage | |
| 通路火山图：一种用于通路引导的差异表达数据可视化交互工具 | OConnell, T. M. | N/A | Pathway Volcano: An interactive tool for pathway guided visualization of differential expression data | |
| 膀胱的开源神经动力学模型 | Lister, E. | N/A | An Open-Source Neurodynamic Model of the Bladder | |
| PyEvoCell：一个增强型大型语言模型单细胞轨迹分析仪表盘 | Mathur, S. | N/A | PyEvoCell: An LLM- Augmented Single Cell Trajectory Analysis Dashboard | |
| 使用穷尽投影寻踪进行自动表型分析 | Moore, W. A. | N/A | Automatic Phenotyping Using Exhaustive Projection Pursuit | |
| 将空间药物异质性与微生物生长动力学在理论和实验中联系起来 | Hu, Z. | N/A | Linking spatial drug heterogeneity to microbial growthdynamics in theory and experiment | |
| 多药外排泵EmrE的C端通过门控运输防止质子泄漏。 | Brousseau, M. | N/A | The C-terminus of the multi-drug efflux pump EmrE prevents proton leak by gating transport | |
| 抗原灵活性在抗原密度较低时支持血凝素特异性抗体的亲和力 | Benegal, A. N. | N/A | Antigen flexibility supports the avidity of hemagglutinin-specific antibodies at low antigen densities | |
| 在糖尿病条件下，缝隙连接的减弱并不会导致功能性β细胞亚群的丧失。 | Levitt, C. H. | N/A | Diminished gap junction coupling under diabetogenic conditions does not drive loss of functional β-cell sub-populations | |
| 协调的蛋白质模块定义了在人卵巢癌模型中单细胞分辨率下对卡铂DNA损伤反应 | Bedia, J. S. | N/A | Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models | |
| 急性葡萄糖摄取抑制下的代谢适应性变化集中于线粒体呼吸，以实现白血病细胞的生存。 | Komza, M. | N/A | Metabolic Adaptations To Acute Glucose Uptake Inhibition Converge Upon Mitochondrial Respiration For Leukemia Cell Survival | |
| 电动自行车骑行：在运动强度领域中的代谢评估 | Bonardi, A. | N/A | E-bike riding: A metabolic evaluation in the context of exercise intensity domains | |
| 急性耐力运动对骨骼肌选择性剪接的影响 | Ahn, A. | N/A | The Impact of Acute Endurance Exercise on Alternative Splicing in Skeletal Muscle | |
| 生菜在低温与强光联合胁迫下持续的非光化学淬灭及PSII修复循环的调控 | Lempiainen, T. | N/A | Sustained non-photochemical quenching and regulation of PSII repair cycle during combined low temperature and high light stress in lettuce | |
| 高质量的荨麻（Urtica dioica ssp. dioica）分阶段基因组组装 | Hirabayashi, K. | N/A | A high-quality phased genome assembly of stinging nettle, Urtica dioica ssp. dioica | |
| 兔形目头颅生物力学及其独特开窗鼻骨的功能意义 | Wood-Bailey, A. P. | N/A | Lagomorph cranial biomechanics and the functional significance of the unique fenestrated rostrum of leporids | |
| 在识别同种巢寄生虫的卵方面，机器学习优于人类评估。 | Hughes, A. E. | N/A | Machine learning outcompetes human assessment in identifying eggs of a conspecific brood parasite | |
| 基于构象集合的框架能够快速开发拉沙病毒疫苗候选者 | Mishra, N. | N/A | Conformational ensemble-based framework enables rapid development of Lassa virus vaccine candidates | |
| 表达皮肤蛋白的成纤维细胞介导了皮肤巨噬细胞微环境的关键作用 | Vollmers, A. C. | N/A | Dermatopontin-expressing fibroblasts mediate an essential skin macrophage niche | |
| 肥大细胞质膜中拓扑结构与脂质域的协同作用控制信号蛋白的定位，并促进其协同激活 | Ghosh, S. | N/A | The Synergy between Topography and Lipid Domains in the Plasma Membrane of Mast Cells Controls the Localization of Signaling Proteins and Facilitates their Coordinated Activation | |
| M2巨噬细胞是子宫内膜异位症种系风险的主要介质，并解释了其与共病特征的多效性 | Ochoa, S. | N/A | M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy with Comorbid Traits | |
| 自然杀伤细胞功能障碍驱动瘢痕疙瘩发病机制 | Zhao, Y. | N/A | Natural killer cell dysfunction drives keloid pathogenesis | |
| 在非常罕见的祖B细胞条件下，多样化的启动结果 | Madden, P. J. | N/A | Diverse priming outcomes under conditions of very rare precursor B cells | |
| 伯克霍尔德菌属（Burkholderia cenocepacia）蛋白质O-连接糖基化生物合成的晚期步骤具有条件性必需性。 | Jebeli, L. | N/A | The Late-Stage Steps of Burkholderia cenocepacia Protein O-Linked Glycan Biosynthesis Are Conditionally Essential. | |
| 沙门氏菌致病岛1编码的小RNA InvR介导了激活因子HilA在沙门氏菌中的转录后反馈调控。 | Hou, Y. | N/A | The Salmonella pathogenicity island 1-encoded small RNA InvR mediates post-transcriptional feedback control of the activator HilA in Salmonella | |
| 多模态CRISPR筛选揭示DDX39B为全局抑制A-to-I RNA编辑的因子 | Wei, T. | N/A | Multimodal CRISPR screens uncover DDX39B as a global repressor of A-to-I RNA editing | |
| 小鼠造血干细胞自我更新和分化在原生造血中的克隆分析 | You, C. | N/A | Clonal analysis of murine HSC self-renewal and differentiation in native hematopoiesis | |
| 性状空间的模式由突变的速率和方式决定。 | Martis, S. | N/A | Trait-space patterning is dictated by the tempo and mode of mutation | |
| 神经元中Imp的丧失通过Syndecan功能引发癫痫行为 | Roy, P. R. | N/A | Loss of neuronal Imp induces seizure behavior through Syndecan function | |
| 利用机械进化模型识别基因组对当地气候的适应性 | Goel, N. | N/A | Identifying genomic adaptation to local climate using a mechanistic evolutionary model | |
| 两种入侵性球蚜物种（铁杉球蚜和菠萝瘿球蚜）的基因组使得对烟碱型乙酰胆碱受体的特性描述成为可能。 | Glendening, A. M. | N/A | Genomes of two invasive Adelges species (hemlock woolly adelgid and pineapple gall adelgid) enable characterization of nicotinic acetylcholine receptors | |
| 从养殖鹿监控计划中进行尸检时分离出的白尾鹿（Odocoileus virginianus）大肠杆菌（Escherichia coli）的系统地理学模式 | Metrailer, M. C. | N/A | Phylogeographic patterns of Escherichia coli isolated from white-tailed deer, Odocoileus virginianus , during necropsy in a farmed deer surveillance program | |
| 低温电子显微镜揭示AAA+ ATP酶Thorase的新型螺旋丝形成结构 | Dar, M. A. | N/A | Cryo-EM Structure of AAA + ATPase Thorase Reveals Novel Helical Filament Formation | |
| 关键通路基因的异源表达导致Paraburkholderia sacchari ITP 101中生物塑料前体产量增加的复杂模式 | Morris, D. | N/A | Heterologous expression of critical pathway genes leads to complex pattern of increased yield of bioplastic precursors in Paraburkholderia sacchari ITP 101 | |
| 未经过抗体修饰的模拟心磷脂的脂质纳米颗粒，实现了体内CAR-T细胞的衰老清除疗法，用于炎症性衰老的治疗。 | Zhang, Z. | N/A | Cardiolipin-mimic lipid nanoparticles without antibody modification delivered senolytic in-vivo CAR-T therapy for inflamm-aging | |
| BioLLM：一个用于整合和基准测试单细胞基础模型的标准化框架 | Qiu, P. | N/A | BioLLM: A Standardized Framework for Integrating and Benchmarking Single-Cell Foundation Models | |
| 调和竞争模型：凝聚物与可溶复合物在转录因子功能中的作用 | Bremer, A. | N/A | Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function | |
| 研究光系统II中TyrD、TyrZ和QA-形成引起的Soret区域电致变色带移 | Boussac, A. | N/A | Investigation of electrochromic band-shifts in the Soret region induced by the formation of TyrD, TyrZ, and QA- in Photosystem II | |
| SFPQ-TFE3基因融合相互调节mTORC1活性，并在一种新型小鼠肾肿瘤发生模型中诱导谱系可塑性 | Asrani, K. | N/A | SFPQ-TFE3 gene fusion reciprocally regulates mTORC1 activity and induces lineage plasticity in a novel mouse model of renal tumorigenesis | |
| 谷氨酰胺补充对饮食诱导肥胖小鼠代谢紊乱、肠道屏障功能及肠道菌群的性别依赖性影响。 | Lefebvre, C. | N/A | Sex-dependent effects of a glutamine supplementation on metabolic disorders, intestinal barrier function and gut microbiota in mice with diet-induced obesity. | |
| 光依赖型乙醇同化作用：模型红藻球石藻（Galdieria sulphuraria）的研究 | Bolychevtseva, Y. V. | N/A | Light-Dependent Ethanol Assimilation By Model Red Microaga Galdieria sulphuraria | |
| 靶向CRISPR筛选揭示了在宿主肠道中维持隐孢子虫生存的关键基因 | Watson, L. C. | N/A | Targeted CRISPR Screens Reveal Genes Essential for Cryptosporidium Survival in the Host Intestine | |
| 痘病毒诱导细胞质形成类似核环境，以促进病毒复制。 | Veratti, P. | N/A | Poxviruses induce a nuclear environment in the cytoplasm to promote viral replication | |
| 噬菌体共培养法：通过共培养实现噬菌体的靶向发现 | Rand, E. A. | N/A | Phage DisCo: targeted discovery of bacteriophages by co-culture | |
| 酵母杀伤毒素K2的丙氨酸扫描揭示了活性关键残基、获得功能变体，并支持前体加工和三维结构的预测。 | Prins, R. C. | N/A | Alanine-scanning of the yeast killer toxin K2 reveals key residues for activity, gain-of-function variants, and supports prediction of precursor processing and 3D structure. | |
| 通过多样性驱动的刺突选择来表征α冠状病毒的表型特征 | Gallo, G. | N/A | Characterising alphacoronavirus phenotypic traits through diversity-driven selection of spike | |
| 对连续采样的家庭队列进行深度测序揭示了Omicron SARS-CoV-2在宿主体内的动态变化及罕见的新型刺突变异体的选择 | Bendall, E. E. | N/A | In depth sequencing of a serially sampled household cohort reveals the within-host dynamics of Omicron SARS-CoV-2 and rare selection of novel spike variants | |
| 碳酸酐酶在土壤细菌泰国伯克霍尔德菌E264引起的岩石风化和pH调节中的作用 | Bell, D. S. | N/A | The role of carbonic anhydrase in rock weathering and pH regulation by the soil bacterium Burkholderia thailandensis E264 | |
| GraFusionNet：融合节点、边和语义特征以增强图表示 | Tahmid, M. T. | N/A | GraFusionNet: Integrating Node, Edge, and Semantic Features for Enhanced Graph Representations | |
| 绘制内体近端蛋白组图谱揭示Retromer作为RAB GTPase调控的枢纽。 | Anton-Plagaro, C. | N/A | Mapping the endosomal proximity proteome reveals Retromer as a hub for RAB GTPase regulation. | |
| 病原体传播中的性别偏见是由热塑性决定的：热塑性决定了性别偏见在病原体传播中的作用。 | Butterworth, N. J. | N/A | The sicker sex is plastic: Thermal plasticity determines sex biases in pathogen transmission | |
| 无花果微型群落的细菌 | Woodruff, G. C. | N/A | The Bacteria of a Fig Microcommunity | |
| 从Pool-Seq数据估计层次F统计量 | Gautier, M. | N/A | Estimating hierarchical F-statistics from Pool-Seq data | |
| TelSPRITE揭示的ALT细胞中的端粒相互作用和结构变异 | Wilson, D. G. | N/A | Telomere interactions and structural variants in ALT cells revealed with TelSPRITE | |
| 一种对Trichogramma kaykai的参考基因组：一种生活在沙漠中的小型寄生蜂，具有竞争性的性比破坏者 | Culotta, J. | N/A | A reference genome for Trichogramma kaykai: A tiny desert-dwelling parasitoid wasp with competing sex-ratio distorters | |
| HiC2Self：用于批量和单细胞Hi-C接触图的自监督去噪 | Yang, R. | N/A | HiC2Self: self-supervised denoising for bulk and single-cell Hi-C contact maps | |
| 一种用于自主控制啮齿动物行为的模块化门控系统 | Lester, A. W. | N/A | A modular gate system for autonomous control of rodent behavior | |
| 利用隐马尔可夫模型在斑马鱼幼体运动中关联大脑和行为状态 | Dommanget-Kott, M. | N/A | Linking Brain and Behavior States in Zebrafish Larvae Locomotion using Hidden Markov Models | |
| 跨进化群的RND多药外排泵的构象可塑性及其对底物特异性的影响 | Lazarova, M. | N/A | Conformational plasticity across phylogenetic clusters of RND multidrug efflux pumps and its impact on substrate specificity | |
| 榛子非特异性脂质转移蛋白Cor a 8是一种具有新脂酶活性的兼职酶。 | Fissore, A. | N/A | Corylus avellana non-specific lipid-transfer protein Cor a 8 is a moonlighting enzyme with a new lipase activity | |
| diaPASEF驱动的化学蛋白质组学实现了深度激酶组相互作用分析 | Woods, K. | N/A | diaPASEF-Powered Chemoproteomics Enables Deep Kinome Interaction Profiling | |
| 14-3-3结合维持与帕金森病相关的激酶LRRK2处于失活状态。 | Martinez Fiesco, J. A. | N/A | 14-3-3 binding maintains the Parkinson's associated kinase LRRK2 in an inactive state | |
| 基于两株禽源致病性大肠杆菌的基因组组装与注释比较 | Zhao, Y. | N/A | Comparison of genomic assembly and annotation based on two clones of avian pathogenic Escherichia coli | |
| HGTs并非SPRs：在存在幽灵分支的情况下，一系列水平基因转移并不会导致一系列子树修剪和嫁接 | Tricou, T. | N/A | HGTs are not SPRs: In the presence of ghost lineages, series of Horizontal Gene Transfers do not result in series of Subtree Pruning and Regrafting | |
| EXO5基因中的一种常见单体型可以影响其蛋白质结构和动力学，并调节基因组稳定性和癌症进展。 | Mazza, F. | N/A | A common haplotype in the EXO5 gene can impact its protein structure and dynamics and modulate genome stability and cancer progression | |
| Roquin通过其两个ROQ结构域结合位点对RNA茎环稳定性表现出相反的作用。 | Tants, J.-N. | N/A | Roquin exhibits opposing effects on RNA stem-loop stability through its two ROQ domain binding sites | |
| 结构导向的突变揭示了多囊蛋白-2/多囊蛋白-1异二聚体的离子通道功能 | Staudner, T. | N/A | Ion channel function of polycystin-2/polycystin-1 heteromer revealed by structure-guided mutagenesis | |
| 在细胞色素bc1的Qo位点，通过冗余网络进行氧化还原激活的质子转移 | Arantes, G. M. | N/A | Redox-Activated Proton Transfer through a Redundant Network in the Qo Site of Cytochrome bc1 | |
| 所有血小板整合素的耗竭会影响止血、血栓形成和肿瘤转移。 | Janus-Bell, E. | N/A | Depletion of all platelet integrins impacts hemostasis, thrombosis and tumor metastasis | |
| 妊娠期间Hofbauer细胞对HIV和CMV的不同免疫反应突显了不断变化的胎盘免疫动态 | Schuch, V. | N/A | Distinct immune responses to HIV and CMV in Hofbauer cells across gestation highlight evolving placental immune dynamics | |
| 揭示根际中促进适应性的遗传联系 | Williams, J. L. | N/A | Uncovering genetic linkages in the rhizosphere contributing to adaptation | |
| 使用TubeTracker进行半自动高内涵花粉性能分析 | Yimga Ouonkap, S. V. | N/A | Semi-automated high content analysis of pollen performance using TubeTracker | |
| 乙醇通过BK钾离子通道以一种新颖的机制改变了秀丽隐杆线虫的机械感觉习惯化。 | Kokan, N. | N/A | Ethanol alters mechanosensory habituation in C. elegans by way of the BK potassium channel through a novel mechanism | |
| 性别、交配状态和遗传背景对果蝇昼夜节律行为的影响 | Akpoghiran, O. | N/A | Effects of sex, mating status, and genetic background on circadian behavior in Drosophila | |
| 通过超图模型进行高阶相互作用分析，以研究多维神经科学数据。 | Bilbao, D. | N/A | Higher-Order Interaction Analysis via Hypergraph Models for Studying Multidimensional Neuroscience Data. | |
| 通过拮抗检测器实现高效的信息素导航 | Wan, X. | N/A | Efficient pheromone navigation via antagonistic detectors | |
| 通过电信号标记解读动机状态和渴望：神经“读心术” | Proverbio, A. M. | N/A | Decoding Motivational States and Craving through Electrical Markers for Neural 'Mind Reading' | |
| 胼胝体间相位对齐的β爆发的产生是TMS诱导的半球间抑制的基础 | Georgiev, C. | N/A | Transcallosal generation of phase aligned beta-bursts underlies TMS-induced interhemispheric inhibition | |
| 在人类恢复视力后，腹侧视觉皮层中的视觉和听觉对象表征 | Raczy, K. | N/A | Visual and auditory object representations in ventral visual cortex after restoring sight in humans | |
| 通过基于邻近的蛋白质组学发现揭示了电突触分子的多样性 | Michel, J. C. | N/A | Electrical synapse molecular diversity revealed by proximity-based proteomic discovery | |
| 由自闭症风险基因DDX3X突变引起的神经发育的性别特异性扰动 | Mossa, A. | N/A | Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X | |
| 丁丙诺啡诱导人胎膜无菌性炎症 | Lynn, T. | N/A | Buprenorphine Induces Human Fetal Membrane Sterile Inflammation | |
| 来自加拿大生长的白香草木犀（Melilotus albus，白甜苜蓿）根瘤中分离得到的一种新型非共生细菌，命名为Phyllobacterium meliloti sp. nov.。 | Bromfield, E. S. P. | N/A | Phyllobacterium meliloti sp. nov. a novel non-symbiotic bacterium isolated from root nodules of Melilotus albus (white sweet clover) grown in Canada | |
| 在胚胎关键期，线粒体活性氧和HIF1-alpha信号的保守作用指导了随后神经系统的发展。 | Sobrid-Camean, D. | N/A | Conserved mitochondrial reactive oxygen species and HIF1-alpha signalling during an embryonic critical period directs subsequent nervous system development | |
| 背腹表面的机械耦合塑造了果蝇的平衡棒 | Song, Y. | N/A | Mechanical coupling between dorsal and ventral surfaces shapes the Drosophila haltere | |
| 五聚体氯离子通道BEST1被胞外GABA激活 | Pant, S. | N/A | The pentameric chloride channel BEST1 is activated by extracellular GABA | |
| 电路模型中归一化强度的神经元异质性 | Song, D. | N/A | Neuronal heterogeneity of normalization strength in a circuit model | |
| 利用扩散成像和纤维束成像评估单侧6-羟多巴胺帕金森病大鼠模型中全脑结构连接的变化 | Moshchin, M. | N/A | Assessing changes in whole-brain structural connectivity in the unilateral 6-hydroxydopamine rat model of Parkinson's Disease using diffusion imaging and tractography | |
| 句子生成过程中语义结构的神经编码 | Giglio, L. | N/A | Neural Encoding of Semantic StructuresDuring Sentence Production | |
| # BioRxiv 2024-11-21 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 长期胞外记录中神经活动追踪的通用框架 | Chaure, F. J. | N/A | General Framework for Tracking Neural Activity Over Long-Term Extracellular Recordings | |
| 岛叶和颞上沟在社交决策中对人际内疚感和责任感的作用 | Gaedeke, M. | N/A | Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions | |
| 撤回：KMT5C 通过有限的序列特征编码了强健的异染色质保留和液态样行为 | Strickfaden, H. | N/A | WITHDRAWN: KMT5C encodes robust heterochromatin retention and liquid-like behavior using limited sequence features | |
| FET融合癌蛋白在癌症中破坏生理性DNA修复网络 | Menon, S. | N/A | FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer | |
| E3连接酶HvST1功能的丧失显著增加了重组 | Orr, J. N. | N/A | Loss of E3 ligase HvST1 function substantially increases recombination | |
| 在半自然条件下饲养的小鼠群体中建模集体行为 | Chen, X. | N/A | Modelling collective behavior in groups of mice housed under semi-naturalistic conditions | |
| 在慢性癫痫期间短暂暴露于托法替尼后的疾病修饰作用。 | Hoffman, O. R. | N/A | Disease modification upon brief exposure to tofacitinib during chronic epilepsy. | |
| 推动基于光泵磁力计的脑磁图技术在早期人类生命中的应用边界 | Corvilain, P. | N/A | Pushing the boundaries of MEG based on optically pumped magnetometers towards early human life | |
| 超特化灵长类动物拥有一套缩减的异生物质代谢细胞色素P450基因。 | Chaney, M. E. | N/A | Hyper-specialized primates possess a reduced suite of xenobiotic-metabolizing cytochrome P450 genes. | |
| 细胞色素P450 CYP72A1182在苋菜（Amaranthus palmeri）种群中代谢型除草剂抗性进化中的作用 | Rigon, C. A. G. | N/A | Function of Cytochrome P450 CYP72A1182 in Metabolic Herbicide Resistance Evolution in Amaranthus palmeri Populations | |
| 脊髓感觉运动回路在三相指令中的作用：使用目标探索过程的模拟方法 | Cattaert, D. | N/A | Role of spinal sensorimotor circuits in triphasic command: a simulation approach using Goal Exploration Process | |
| 人类肠道微生物群中普遍存在的定向选择 | Wolff, R. | N/A | Pervasive selective sweeps across human gut microbiomes | |
| 通过集体迁徙实现的非遗传性适应 | Vo, L. | N/A | Non-genetic adaptation by collective migration | |
| 推断在共进化动力学过程中产生的噬菌体-细菌相互作用表型的菌株水平突变驱动因素 | Lucia-Sanz, A. | N/A | Inferring strain-level mutational drivers of phage-bacteria interaction phenotypes arising during coevolutionary dynamics | |
| 最小化蛋白质组再分配解释了碳源分级利用中的代谢转变 | Liu, Z. | N/A | Minimization of proteome reallocation explains metabolic transition in hierarchical utilization of carbon sources | |
| 利用蛋白质拆分重组策略调控PLD酶活性 | yao, y. | N/A | Using split protein reassembly strategy to control PLD enzymatic activity | |
| 双胞胎的故事：胞内与胞外甲酸盐在调控鼠伤寒沙门氏菌鞭毛及毒力岛-1基因中的不同角色 | MUKHERJEE, D. | N/A | A Tale of Twins: The Distinct Roles of Intracellular and Extracellular Formate in Regulating Flagellar and Pathogenicity Island-1 Genes in Salmonella Typhimurium | |
| 谷氨酸能突触表型的睡眠需求驱动振荡 | Vogt, K. | N/A | Sleep need driven oscillation of glutamatergic synaptic phenotype | |
| 中性转录组重塑促进物种水平上的QDR进化能力 | Delplace, F. | N/A | Neutral transcriptome rewiring promotes QDR evolvability at the species level | |
| 靶向EGFR配体Epiregulin的抗体药物偶联物在结直肠癌中展现出强大的抗肿瘤活性 | Jacob, J. | N/A | Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer | |
| 听觉系统中灵活的巧合检测的解剖学和生理学基础 | Kreeger, L. J. | N/A | An Anatomical and Physiological Basis for Flexible Coincidence Detection in the Auditory System | |
| 增加第5层Martinotti细胞的兴奋性会降低锥体细胞群体的可塑性，并改善运动执行能力。 | Malfatti, T. | N/A | Increased layer 5 Martinotti cell excitation reduces pyramidal cell population plasticity and improves motor execution | |
| 自适应分块提高了前额叶皮层和基底神经节回路中的有效工作记忆容量。 | Soni, A. | N/A | Adaptive chunking improves effective working memory capacity in a prefrontal cortex and basal ganglia circuit | |
| 盐胁迫下根冠比的自然变异揭示了SR3G作为拟南芥根木栓质化和盐耐受性的负调控因子 | Ishka, M. R. | N/A | Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis | |
| 一个跨物种框架，用于研究感知证据的积累 | Chakravarty, S. | N/A | A cross-species framework for investigating perceptual evidence accumulation | |
| 单细胞转录组特征分析（SCOTCH）：通过长读长单细胞RNA测序进行基因表达的转录本水平特征分析 | Xu, Z. | N/A | Single-Cell Omics for Transcriptome CHaracterization (SCOTCH): isoform-level characterization of gene expression through long-read single-cell RNA sequencing | |
| 海马体涟漪预示人类在短暂休息期间的运动学习 | Sjogard, M. | N/A | Hippocampal ripples predict motor learning during brief rest breaks in humans | |
| 当药物抗性突变率不同时的最佳抗菌药物组合 | Delaney, O. | N/A | Optimal antimicrobial dosing combinations when drug-resistance mutation rates differ | |
| 一种关于等频和跨频神经耦合的新视角：大脑网络功能的整合与分离 | Mateos, D. M. | N/A | A novel perspective on equal and cross-frequency neural coupling: integration and segregation of the brain networks' function | |
| 基于力矩臂的梯度指定优化自动肌肉路径校准 | Chen, Z. | N/A | Automated muscle path calibration with gradient-specified optimization based on moment arm | |
| 早期视觉皮层和面部选择性脑区中空间选择性的常见模式 | Morsi, A. Y. | N/A | Common patterns of spatial selectivity in early visual cortex and face-selective brain regions | |
| 利用深度学习剖析转录起始的顺式调控语法 | Cochran, K. | N/A | Dissecting the cis-regulatory syntax of transcription initiation with deep learning | |
| 纹状体胆碱能中间神经元的暂停反应需要Kv1通道，在运动障碍小鼠中缺失，并通过多巴胺D5受体反向激动作用得以恢复 | Tubert, C. | N/A | Striatal cholinergic interneuron pause response requires Kv1 channels, is absent in dyskinetic mice, and is restored by dopamine D5 receptor inverse agonism | |
| 一种基于代理的肿瘤生长建模框架，整合了细胞动力学的机械和进化方面 | Macnamara, C. K. | N/A | An agent-based modelling framework for tumour growth incorporating mechanical and evolutionary aspects of cell dynamics | |
| 表达Ly49受体家族中的单一抑制性成员足以使NK细胞获得效应功能。 | Piersma, S. J. | N/A | Expression of a single inhibitory member of the Ly49 receptor family is sufficient to license NK cells for effector functions | |
| 支原体滑行运动中F1样ATP酶的二聚体组装 | Toyonaga, T. | N/A | Dimeric assembly of F1-like ATPase for the gliding motility of Mycoplasma | |
| 双语语言处理依赖于共享的语义表征，这些表征受每种语言的调节。 | Chen, C. | N/A | Bilingual language processing relies on shared semantic representations that are modulated by each language | |
| 大型溞全基因组DNA甲基化模式揭示了其靶向于启动子近端区域 | Liu, R. | N/A | Genome-wide DNA Methylation Patterns in Daphnia magna Reveal Targeting to Promoter Proximal Regions | |
| PTEN通过亚细胞定位调节瓣膜间质细胞中的肌成纤维细胞激活 | Batan, D. | N/A | PTEN Regulates Myofibroblast Activation in Valvular Interstitial Cells based on Subcellular Localization | |
| 适应侧步控制以沿蜿蜒路径行走 | Render, A. C. | N/A | Adapting Lateral Stepping Control to Walk on Winding Paths | |
| 长寿物种中本地适应性的演变 | Habluetzel, L. | N/A | The evolution of local adaptation in long-lived species | |
| PA28γ通过C1QBP提升线粒体功能，从而促进肿瘤的恶性进展。 | Wang, J. | N/A | PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP | |
| 单细胞自发荧光成像揭示了中性粒细胞在跨生物系统激活后立即发生的代谢转变 | Datta, R. | N/A | Single cell autofluorescence imaging reveals immediate metabolic shifts of neutrophils with activation across biological systems | |
| 人类可以利用正负光谱时间相关性来检测音调的上升和下降 | Vaziri, P. A. | N/A | Humans can use positive and negative spectrotemporal correlations to detect rising and falling pitch | |
| 新型细胞外基质蛋白SNED1通过RGD结合整合素α5β1和αvβ3介导细胞粘附 | Pally, D. | N/A | The novel ECM protein SNED1 mediates cell adhesion via the RGD-binding integrins α5β1 and αvβ3 | |
| 肽段感知化学语言模型成功预测了环肽的膜扩散 | Feller, A. L. | N/A | Peptide-aware chemical language model successfully predicts membrane diffusion of cyclic peptides | |
| 夜幕下的庇护：夜间躲避人工光源或可降低搁浅海鸟的风险 | Brown, T. M. | N/A | Under Cover of Darkness: Refuge from Artificial Light at Night may Mitigate Risks to Stranded Seabirds | |
| scatterbar：一个用于在空间解析坐标上可视化比例数据的R包 | Velazquez, D. | N/A | scatterbar: an R package for visualizing proportional data across spatially resolved coordinates | |
| 神经生长因子受体跨膜螺旋相互作用的模拟揭示了活性状态和不同的信号传导机制 | Athanasiou, C. | N/A | Simulation of neurotrophin receptor transmembrane helix interactions reveals active states and distinct signaling mechanisms | |
| 祖传功能的重新分配是海洋捕食性蜗牛毒液生产进化的基础 | Zancolli, G. | N/A | Redistribution of ancestral functions underlies the evolution of venom production in marine predatory snails | |
| 一项横跨大陆的实验阐明了一种世界性植物在空间和时间上对气候的（不）适应性。 | Albano, L. J. | N/A | A transcontinental experiment elucidates (mal)adaptation of a cosmopolitan plant to climate in space and time | |
| 在编码稀疏基因组的物种中，使用两步法从群体基因组数据推断人口统计学和选择历史：应用于人类数据 | Soni, V. | N/A | Inferring demographic and selective histories from population genomic data using a two-step approach in species with coding-sparse genomes: an application to human data | |
| 肝线粒体呼吸对复杂III缺陷小鼠的正常体温维持至关重要，这些小鼠的棕色脂肪组织产热功能受损。 | Banerjee, R. | N/A | Hepatic mitochondrial respiration is crucial for euthermia in complex III-deficient mice with impaired brown adipose tissue thermogenesis | |
| 在唐氏综合症B细胞急性淋巴母细胞白血病中，可以通过使用Venetoclax来针对其代谢脆弱性。 | Jones, D. | N/A | Metabolic vulnerabilities in Down syndrome B-cell acute lymphoblastic leukemia can be targeted using Venetoclax | |
| 表达嵌合细胞因子受体的巨噬细胞在IL-10或TGFβ刺激下表现出炎症表型并具有抗肿瘤活性。 | Traxel, S. | N/A | Macrophages expressing chimeric cytokine receptors have an inflammatory phenotype and anti-tumoral activity upon IL-10 or TGFβ stimulation | |
| 用于双光子亚细胞钙成像的预处理工具箱 | Jiang, A. | N/A | A preprocessing toolbox for 2-photon subcellular calcium imaging | |
| 与亚临床性淡漠相关的前运动回路 | Derosiere, G. | N/A | Fronto-motor circuits linked to subclinical apathy | |
| 巨细胞病毒与脑萎缩对不同人群免疫衰老轨迹的影响 | Touil, H. | N/A | Relation of CMV and brain atrophy to trajectories of immunosenescence in diverse populations | |
| 多成分营养补充剂与衰老小鼠的衰老干预具有可比的抗衰老功效 | Brookes, C. | N/A | Comparable anti-ageing efficacies of a multi-ingredient nutraceutical and a senolytic intervention in old mice | |
| 利用特征结构感知的直系同源分配方法，追踪植物细胞壁降解酶在整个生命树中的分类分布 | Tran, V. | N/A | Tracing the taxonomic distribution of plant cell wall degrading enzymes across the tree of life using feature architecture aware orthology assignments | |
| 稳定感染重组卡波西肉瘤相关疱疹病毒的内皮细胞表现出独特的粘弹性和形态学特性。 | Shabangu, M. M. | N/A | Endothelial cells stably infected with recombinant Kaposi's sarcoma-associated herpesvirus display distinct viscoelastic and morphological properties | |
| 象牙喙啄木鸟与蓝松鸦在频谱图层面的对比显示出差异 | Williams, J. D. | N/A | Ivory-billed Woodpecker and Blue Jay kent comparisons at spectrogram level reveal differences | |
| 模拟微重力加速α-突触核蛋白聚集并诱导体外帕金森病模型中的氧化应激 | Lentini, V. | N/A | Simulated microgravity accelerates alpha-synuclein aggregation and induces oxidative stress in an in vitro Parkinson disease model | |
| 《昆虫生物群落图集》数据：瑞典和马达加斯加陆生节肢动物的宏条形码调查 | Miraldo, A. | N/A | Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar | |
| Cloudgene 3：将Nextflow管道转化为强大的Web服务 | Forer, L. | N/A | Cloudgene 3: Transforming Nextflow Pipelines into Powerful Web Services | |
| 人类精子发生导致核孔结构和功能的减少 | dos Santos, A. | N/A | Human spermatogenesis leads to a reduced nuclear pore structure and function | |
| 纹状体胆碱能中间神经元的同步激活可诱导局部血清素释放。 | Matityahu, L. | N/A | Synchronous activation of striatal cholinergic interneurons induces local serotonin release | |
| 注释冷冻电镜三维重构体积：一个机器学习挑战 | Peck, A. | N/A | Annotating CryoET Volumes: A Machine Learning Challenge | |
| 微管动态由聚类原丝的构象和稳定性决定。 | Kalutskii, M. | N/A | Microtubule dynamics are defined by conformations and stability of clustered protofilaments | |
| 通过溶解度改变探索组合疗法的作用机制：推进AML治疗 | Gholizadeh, E. | N/A | Exploring Mechanisms of Action in Combinatorial Therapies through Solubility Alterations: Advancing AML Treatment | |
| 转录因子GABPA是原始多能性的主调控因子。 | Zhou, C. | N/A | The transcription factor GABPA is a master regulator of naive pluripotency | |
| 动物编码的非核糖体途径合成布尔萨特林类似物 | Venugopalan, A. | N/A | Animal-encoded nonribosomal pathway to bursatellin analogs | |
| 一种用于狨猴神经科学设备的开放获取资源 | Rollin, I. Z. | N/A | An Open Access Resource for Marmoset Neuroscientific Apparatus | |
| 大规模衣壳介导的细菌基因组DNA在肠道微生物群中的移动 | Borodovich, T. | N/A | Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome | |
| 博茨瓦纳、加蓬、肯尼亚、南非和美国非洲象体内隐性感染的象内皮细胞嗜性疱疹病毒和象伽玛疱疹病毒 | Pearson, V. R. | N/A | Quiescent Infections of Elephant Endotheliotropic Herpesviruses and Elephant Gammaherpesviruses in African Elephants in Botswana, Gabon, Kenya, South Africa and USA | |
| 撤回：通过计算优化和结构工程显著提高接枝纳米抗体的抗病毒疗效 | HUO, L. | N/A | WITHDRAWN: Significantly enhancing antiviral efficacy by computational optimization and structural engineering of grafted nanobodies | |
| 基质硬度决定了人类肺成纤维细胞中独特的阿霉素诱导的衰老相关分泌表型和转录组特征 | Du, H. | N/A | Substrate Stiffness Dictates Unique Doxorubicin-induced Senescence-associated Secretory Phenotypes and Transcriptomic Signatures in Human Pulmonary Fibroblasts | |
| 准备用于核型分析和荧光原位杂交（FISH）的高质量番红花属物种染色体铺展 | El-nagish, A. | N/A | Preparing high-quality chromosome spreads from Crocus species for karyotyping and FISH | |
| 酶催化纤维蛋白网络的凝固性颗粒水凝胶用于内源性组织再生 | Deng, Z. | N/A | Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration | |
| 单细胞空间映射揭示了在早期结直肠癌形成过程中细胞类型组成的改变及组织微环境的变迁 | Guha, T. K. | N/A | Single-cell spatial mapping reveals alteration of cell type composition and tissue microenvironment during early colorectal cancer formation | |
| 慢性神经病理性疼痛对高效力μ型阿片受体激动剂芬太尼自我给药的影响 | Burgess, G. E. | N/A | The effects of chronic neuropathic pain on the self-administration of highly potent MOR agonist, fentanyl | |
| 电荷介导的转化技术在高效植物基因组编辑中的应用 | Augustine, S. M. | N/A | Electrical charge-mediated transformation for efficient plant genome editing | |
| 综合计算框架Dyscovr将突变驱动基因与19种癌症类型的表达失调联系起来 | Geraghty, S. E. | N/A | Integrative Computational Framework, Dyscovr, Links Mutated Driver Genes to Expression Dysregulation Across 19 Cancer Types | |
| 开发新型外周神经袖带信号与峰电位速度分析工具 | Klus, J. | N/A | Development of novel signal and spike velocity analysis tools in peripheral nerve cuffs | |
| 单变量和多变量fMRI分析揭示的被动手指运动的运动学特征的神经相关性 | Pamplona, G. S. P. | N/A | Neural correlates of kinematic features of passive finger movement revealed by univariate and multivariate fMRI analyses | |
| 水生丛毛单胞菌（Comamonas aquatica）抑制TIR-1/SARM1诱导的轴突退化。 | O'Connor, L. C. | N/A | Comamonas aquatica inhibits TIR-1/SARM1 induced axon degeneration | |
| 从TCR T细胞与癌细胞相互作用的活细胞成像中分析细胞行为 | Verma, A. | N/A | Cellular behavior analysis from live-cell imaging of TCR T cell-cancer cell interactions | |
| Anillin 在 Rho 信号通路介导的紧密连接重塑过程中调节收缩力和屏障功能 | Craig, Z. | N/A | Anillin tunes contractility and regulates barrier function during Rho flare-mediated tight junction remodeling | |
| 延迟蛋白质转运保护线粒体免受有毒的CAT尾蛋白的侵害 | Bertram, N. | N/A | Delayed protein translocation protects mitochondria against toxic CAT-tailed proteins | |
| 工程化装配体以模拟移植物与宿主骨骼肌的相互作用 | Rossi, L. | N/A | Engineering assembloids to mimic graft-host skeletal muscle interaction | |
| 不同人类冠状病毒的核衣壳（N）蛋白在诱导细胞质凝聚物形成的能力上表现出差异。 | Tikhomirova, M. A. | N/A | The nucleocapsid (N) proteins of different human coronaviruses demonstrate a variable capacity to induce the formation of cytoplasmic condensates | |
| 一个基于过程的模型，模拟德国库蚊（Culex pipiens s.s./Cx. torrentium）的生命周期 | Rauhöft, L. | N/A | A process-based model simulating the life cycle of Culex pipines s.s./Cx. torrentium in Germany | |
| 将野生鸣唱文化重新引入极度濒危的鸣禽中 | Appleby, D. L. | N/A | Reintroduction of wild song culture to a critically endangered songbird | |
| 宿主特征和环境变异共同塑造了野生三刺鱼肠道微生物群的多样性 | Härer, A. | N/A | Host traits and environmental variation shape gut microbiota diversity in wild threespine stickleback | |
| 不可穿越边界栖息地中的家域溢出：原因、偏差及使用自相关核密度估计的修正 | Hollins, J. P. W. | N/A | Home range spillover in habitats with impassable boundaries: Causes, biases, and corrections using autocorrelated kernel density estimation | |
| 空间背景使植物对硝化作用的控制得以进化 | Ardichvili, A. N. | N/A | Spatial context allows the evolution the control of nitrification by plants | |
| 刺胞动物机械感觉神经元细胞类型多样性的结构分子和发育学证据 | Baranyk, J. | N/A | Structural molecular and developmental evidence for cell-type diversity in cnidarian mechanosensory neurons | |
| 尽管遗传差异的证据很少，但休眠和非休眠云杉芽虫株系之间的基因表达发生了重大变化。 | van der Burg, K. R. L. | N/A | Major changes in gene expression between strains of diapausing and non-diapause spruce budworm despite little evidence of genetic divergence | |
| 利用数学约束条件解释等位基因共享差异的狭窄范围 | Liu, X. | N/A | Using mathematical constraints to explain narrow ranges for allele-sharing dissimilarities | |
| ERGA-BGE 北山羊（Rupicapra rupicapra）参考基因组：欧洲最丰富的山地有蹄类动物 | Buzan, E. | N/A | ERGA-BGE Reference Genome of the Northern chamois (Rupicapra rupicapra): Europe's most abundant mountain ungulate | |
| 利用视频技术进行深度学习作为测量家禽感染的工具 | Scheidwasser, N. | N/A | Deep learning from videography as a tool for measuring infection in poultry | |
| 超镁铁质岩石生物加速风化性能的跨物种比较 | Plante, L. | N/A | Cross-species Comparison of Ultramafic Rock Bio-accelerated Weathering Performance | |
| 基于深度学习的长RNA二级结构预测的分治法：专注于假结识别 | Omnes, L. | N/A | A divide-and-conquer approach based on deep learning for long RNA secondary structure prediction: focus on pseudoknots identification | |
| Nerpa 2：将生物合成基因簇与非核糖体肽结构相链接 | Olkhovskii, I. | N/A | Nerpa 2: linking biosynthetic gene clusters tononribosomal peptide structures | |
| 盖亚：一种用于微生物蛋白质的上下文感知序列搜索与发现工具 | Jha, N. | N/A | Gaia: A Context-Aware Sequence Search and Discovery Tool for Microbial Proteins | |
| 通过长读长测序在细胞类型分辨率下进行表观遗传衰老特征分析 | Eames, A. | N/A | Profiling Epigenetic Aging at Cell-Type Resolution Through Long-Read Sequencing | |
| 蛋白质语言可视化工具：语言模型时代的序列相似性网络 | Herrera, J. E. | N/A | The Protein Language Visualizer: Sequence Similarity Networks for the Era of Language Models | |
| 伴侣蛋白TRiC在哺乳动物精子鞭毛中局部翻译的蛋白质折叠过程中，起到连接径向辐条的作用。 | Cong, Y. | N/A | Chaperonin TRiC bridges radial spokes for folding proteins locally translated in mammalian sperm flagella | |
| 固醇裂解活化蛋白识别固醇的分子决定因素 | Khiewdee, C. | N/A | Molecular determinant of sterol recognition by sterol cleavage activatory protein | |
| HIF2α负调控MYCN蛋白水平，并促进神经母细胞瘤中的低风险去甲肾上腺素表型。 | Yuan, J. | N/A | HIF2α negatively regulates MYCN protein levels and promotes a low-risk noradrenergic phenotype in neuroblastoma. | |
| 基于三嗪的水凝胶的设计与合成，用于联合靶向多柔比星递送和PI3K抑制 | Mandal, S. | N/A | Design and synthesis of triazine-based hydrogel for combined targeted doxorubicin delivery and PI3Kinhibition | |
| 针对实验性腹膜损伤的STING靶向治疗：腹膜透析疗法的新方法 | Marchant, V. | N/A | Targeting STING in experimental peritoneal damage: a novel approach in peritoneal dialysis therapy | |
| 设计改变GPCR G蛋白亚型选择性的变构调节剂 | Moore, M. N. | N/A | Design of allosteric modulators that change GPCR G protein subtype selectivity | |
| 设计改变GPCR G蛋白亚型选择性的变构调节剂 | Moore, M. N. | N/A | Design of allosteric modulators that change GPCR G protein subtype selectivity | |
| 西方饮食对田鼠身体组成、运动表现及血液生化特征的影响 | HSEIKY, A. | N/A | Effect of Western diet on body composition, locomotor performance and blood biochemical profile in the bank vole | |
| 蚜虫效应蛋白通过招募防御蛋白到处理小体来抑制植物免疫 | Liu, Q. | N/A | Aphid effectors suppress plant immunity via recruiting defence proteins to processing bodies | |
| 体外血管化复合异体移植物的预处理：范围综述 | Baker, C. E. | N/A | Pre-treatments of Ex vivo Vascularized Composite Allografts: A Scoping Review | |
| 深度核逆向：快速且精准的分子相互作用预测，助力药物设计 | Myers, S. A. | N/A | Deep Kernel Inversion: Rapid and Accurate Molecular Interaction Prediction for Drug Design | |
| 罕见病和常见病的基本模型中人类疾病机制的表示学习 | Ravandi, B. | N/A | Representation Learning of Human Disease Mechanisms for a Foundation Model in Rare and Common Diseases | |
| Ca2+和G蛋白对Cav2.2 N型Ca2+通道的复杂调控 | Thomas, J. | N/A | Complex regulation of Cav2.2 N-type Ca2+ channels by Ca2+ and G-proteins | |
| 布洛卡区负责言语产生，受肺功能调节。 | Siyu, C. | N/A | Broca's area responsible for speech production is regulated by lung functions | |
| 多巴胺能亚类神经元中显著不同的神经递质释放策略 | Dorrego-Rivas, A. | N/A | Strikingly different neurotransmitter release strategies in dopaminergic subclasses | |
| 酒精戒断以一种依赖于中间神经元和性别特异性的方式改变了前外侧皮质区的抑制性环境 | Quadir, S. G. | N/A | Alcohol Withdrawal Alters the Inhibitory Landscape of the Prelimbic Cortex in an Interneuron- and Sex-specific Manner | |
| 在感觉学习过程中，对生长抑素中间神经元进行长期、亚型特异性的调控 | Zhu, M. | N/A | Long-lasting, subtype-specific regulation of somatostatin interneurons during sensory learning | |
| 在脆性X综合征小鼠模型中前肢抓取学习缺陷 | Young, L. F. | N/A | Deficits in forelimb reach learning in a mouse model of Fragile X syndrome | |
| 慢性尼古丁暴露下健康与条件性Presenilin-1/2敲除痴呆模型小鼠的代谢差异 | Si, Y. | N/A | Metabolic Divergence Between Healthy and Conditional Presenilin-1/2 knockout Dementia Model Mice under Chronic Nicotine exposure | |
| 超越表象：通过深度学习预测脑电图以揭示脑活动深层次的奥秘 | Semenkov, I. | N/A | Beyond the Surface: Revealing the Depths of Brain Activity by Predicting fMRI from EEG with Deep Learning | |
| 猕猴在扫视期间出现的二维视觉错位现象 | Baumann, M. P. | N/A | Two-dimensional perisaccadic visual mislocalization in rhesus macaque monkeys | |
| 磷脂酰丝氨酸翻转酶1（PLSCR1）调控干扰素-λ受体1（IFN-lambdaR1）及干扰素-λ信号在甲型流感病毒（IAV）感染中的作用 | Yang, A. X. | N/A | Phospholipid Scramblase 1 (PLSCR1) Regulates Interferon-Lambda Receptor 1 (IFN-lambdaR1) and IFN-lambda Signaling in Influenza A Virus (IAV) Infection | |
| 在具有口腔风险习惯的斯里兰卡男性患者群体的口腔鳞状细胞癌（OSCC）组织中，微生物失调现象明显：重新审视以确认 | Perera, M. L. | N/A | Microbial dysbiosis is evident in oral squamous cell carcinoma (OSCC) tissues of a group of Sri Lankan male patients with oral risk habits: Revisiting for confirming | |
| 检测到中大西洋赤道圣彼得和圣保罗群岛海鸟环境粪便样本中的德尔塔冠状病毒 | Gomes, F. | N/A | Detection of Deltacoronavirus in Environmental Fecal Samples from Seabirds in the Saint Peter and Saint Paul Archipelago, central equatorial Atlantic Ocean | |
| Piezo1 通过平衡膜张力和皮质肌动蛋白收缩力，以稳定细胞间连接并维持上皮屏障的完整性。 | Javed, A. | N/A | Piezo1 balances membrane tension and cortical contractility to stabilize intercellular junctions and maintain epithelial barrier integrity | |
| 在浑浊和污染的水质条件下，石珊瑚（Orbicella faveolata）的加速生长 | Lizcano-Sandoval, L. | N/A | Accelerated growth of the scleractinian coral Orbicella faveolata under turbid and polluted water conditions | |
| 古代气候变化和选择放松塑造了北美洞穴鱼类的洞穴定殖 | Hart, P. | N/A | Ancient climate changes and relaxed selection shape cave colonisation in North American cavefishes | |
| 利用支系特异性靶向富集诱饵集构建黄芪（豆科）的强健骨干 | Buono, D. | N/A | Building a robust backbone for Astragalus (Fabaceae) using a clade-specific target enrichment bait set | |
| 揭示性别、个体表型变异与觅食策略中的社会信号之间的复杂关系 | Leitao, A. V. | N/A | Revealing complex relationships between sex, individuals' phenotype variation and social signalling in foraging strategies | |
| 利用磁性分选控制人干细胞衍生的胰岛组成 | Kelley, A. B. | N/A | Controlling human stem cell-derived islet composition using magnetic sorting | |
| 交配和蜕皮激素信号传导改变了雌性果蝇肠道中的生长、代谢和消化效率 | Kandelouei, T. N. | N/A | Mating and ecdysone signaling modify growth, metabolism, and digestive efficiency in the female Drosophila gut | |
| 人类骨骼肌在反复抗阻训练后，不仅表现出可逆的蛋白质组学特征，还保留了蛋白质组学记忆。 | Hulmi, J. J. | N/A | Human skeletal muscle possesses both reversible proteomic signatures and a retained proteomic memory after repeated resistance training | |
| 地钱（Marchantia polymorpha）亚种ruderalis的群体基因组学研究揭示了气候适应的证据 | Dolan, L. | N/A | Population genomics of Marchantia polymorpha subspecies ruderalis reveals evidence of climate adaptation | |
| 牛粪肥料中含有什么？深入了解其对植物防御系统支持的潜力 | Wilson, K. | N/A | What's in Cow Dung Manure? Insights into Its Potential for Supporting Plant Defense System | |
| 映射对象空间维度：从时间动态中获得的新见解 | Kidder, A. | N/A | Mapping object space dimensions: new insights from temporal dynamics | |
| 扣带回和纹状体中枢与早期技能学习有关。 | Sugata, H. | N/A | Cingulate and striatal hubs are linked to early skill learning | |
| 定义不同RNA货物排序到细胞外囊泡中的参数 | Batish, M. | N/A | Defining the parameters for sorting of different RNA cargo into Extracellular vesicles | |
| 网格蛋白通过共同维持高尔基体的结构-功能关系来支持细胞外基质的分泌。 | Stevenson, N. | N/A | Golgins support extracellular matrix secretion by collectively maintaining the Golgi structure-function relationship | |
| 优化PSC培养以生成神经类器官 | Sutcliffe, M. A. | N/A | Optimizing PSC culture for generating neural organoids | |
| 组织环境驱动胎儿膜和绒毛膜绒毛中滋养层分化的区域差异 | Yang, L. | N/A | Tissue Context Drives Regional Differences in Trophoblast Differentiation in Fetal Membranes and Chorionic Villi | |
| 象海豹在冰期后对南大洋的重新占领是从多个冰期避难所发生的。 | Berg, A. | N/A | Postglacial recolonization of the Southern Ocean by elephant seals occurred from multiple glacial refugia | |
| 真菌来源的tRNAs在兰花线粒体中表达并被氨酰化。 | Warren, J. M. | N/A | Fungal-derived tRNAs are expressed and aminoacylated in orchid mitochondria | |
| 远程控制性染色体的减数分裂驱动 | Greenberg, N. L. | N/A | Remote-control meiotic drive of sex chromosomes | |
| 一种多模态体内组合遗传筛选平台揭示了肝脏功能调控因子 | Saunders, R. A. | N/A | A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function | |
| 一种多模态体内组合遗传筛选平台揭示了肝脏功能调控因子 | Saunders, R. A. | N/A | A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function | |
| 肿瘤-基质相互作用下游的信号传导调控粘液性结直肠腺癌的顶基极性 | Pasquier, N. | N/A | Signaling downstream of tumor-stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity | |
| 组蛋白H2B变体的异常表达重塑染色质结构并改变致癌基因表达程序 | Saintilnord, W. N. | N/A | Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programs | |
| 组蛋白H2B变体的异常表达会重塑染色质结构，并改变致癌基因表达程序。 | Saintilnord, W. N. | N/A | Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programs | |
| 人口密集的细胞和细胞器分割的多平面深度学习管道 | Fulton, S. | N/A | Densely Populated Cell and Organelles Segmentation With Multi-Plane Deep Learning Pipeline | |
| 人口密集的细胞和细胞器分割的多平面深度学习管道 | Fulton, S. | N/A | Densely Populated Cell and Organelles Segmentation With Multi-Plane Deep Learning Pipeline | |
| 一个用于去噪单细胞RNA测序数据的深度神经网络 | Sharifitabar, M. | N/A | A deep neural network to de-noise single-cell RNAsequencing data | |
| 胶质瘤患者的临床和分子特征：miR-21在组织和血清中的表达作为预后生物标志物 | Laghari, A. A. | N/A | Clinical and Molecular Characterization of Glioma Patients: miR-21 Expression as a Prognostic Biomarker in Tissue and Serum | |
| 探索拟杆菌属物种在抑郁症进展中的假定作用：基于宏基因组分析的见解 | Li, Z. | N/A | Exploring the Hypothetical Role of Bacteroides Species in Depression Progression: Insights from Metagenomic Analysis | |
| 验证弱磁场对涡虫中超氧化物影响的自由基对机制预测 | Rishabh, | N/A | Verification of radical pair mechanism predictions for weak magnetic field effects on superoxide in planarians | |
| 基于Mora-ERP的RNN-Transformer用于解码静默日语演讲期间的单次脑电图 | Yamazaki, T. | N/A | Mora-ERP-based RNN-Transformer for decoding single-trial EEGs during silent Japanese speeches | |
| 社交触摸的平衡稳定益处：个体年龄及伴侣相对身体特征的影响 | Johannsen, L. | N/A | The balance stabilising benefit of social touch: influence of an individual's age and the partner's relative body characteristics | |
| 严重创伤性脑损伤会暂时影响脑血流、内皮细胞表型和纤毛。 | Gupta, A. | N/A | Severe traumatic brain injury temporally affects cerebral blood flow, endothelial cell phenotype, and cilia | |
| 乳酸通过靶向GluN2B亚基C端域中的半胱氨酸的细胞内氧化还原机制，增强NMDA受体电流：对突触可塑性的影响 | Fiumelli, H. | N/A | Lactate potentiates NMDA receptor currents via an intracellular redox mechanism targeting cysteines in the C-terminal domain of GluN2B subunits: implications for synaptic plasticity | |
| 全转录组钴氯化物诱导的低氧应答长非编码RNA的鉴定及其受细胞质mRNA加帽酶调控的研究 | Ghosh, P. | N/A | Identification of transcriptome-wide cobalt chloride-induced hypoxia-responsive long noncoding RNAs regulated by cytoplasmic mRNA capping enzyme | |
| 曲霉属的转录因子BrlA被用于细胞壁应激的非分生孢子形成反应中。 | Edwards, H. | N/A | Aspergillus nidulans Transcription Factor BrlA is Utilized in a Conidiation-Independent Response to Cell-Wall Stress | |
| 桥粒斑蛋白是一种桥粒机械感受器 | Dong, Y. | N/A | Desmoplakin is a desmosomal mechanosensor | |
| 静息的神经干细胞会短暂地转变为“神经元”以协调重新激活。 | Gherghina, L.-Y. | N/A | Quiescent neural stem cells transiently become 'neurons' to coordinate reactivation | |
| 多年干旱增强了正负功能多样性对树木生长响应的影响 | Serrano-Leon, H. | N/A | Multi-year drought strengthens positive and negative functional diversity effects on tree growth response | |
| ScTree：可扩展且稳健的流行病学和基因组数据机械整合方法，用于传播树推断 | Waddel, H. | N/A | ScTree: Scalable and robust mechanistic integration of epidemiological and genomic data for transmission tree inference | |
| 甜菜根蛆（Tetanops myopaeformis）转录组样本统计数据，涉及其对甜菜（Beta vulgaris ssp. vulgaris）的易感性和抗性反应 | Acharya, S. | N/A | The sugar beet root maggot, Tetanops myopaeformis transcriptome sample statistics in relation to it experiencing susceptible and resistant reactions with sugar beet, Beta vulgaris ssp. vulgaris | |
| 不同跑步速度下跑步鞋堆叠高度对跑步姿势和稳定性的影响 | Kettner, C. | N/A | The effects of running shoe stack height on running style and stability during level running at different running speeds | |
| 原位整合多孔聚乙烯纳米膜与伤口渗出液以实现无痕愈合 | Yuan, S. | N/A | In Situ Integration of Porous Polyethylene Nanomembrane with Wound Exudates for Scarless Healing | |
| 通过投影到形态学相关曲线上来识别空间变异基因 | Nicol, P. B. | N/A | Identifying spatially variable genes by projecting to morphologically relevant curves | |
| 解析心肌梗死后修复性心肌成纤维细胞的分子激活机制 | Hernandez, S. C. | N/A | Unravelling the molecular activation of the reparative cardiac fibroblasts after myocardial infarction | |
| 解析心肌梗死后修复性心脏成纤维细胞的分子激活机制 | Hernandez, S. C. | N/A | Unravelling the molecular activation of the reparative cardiac fibroblasts after myocardial infarction | |
| 从扇形蠕虫中表征和工程化了一种蓝色敏感、Gi/o偏向且双稳态的纤毛视蛋白 | Fukuzawa, S. | N/A | Characterization and engineering of a blue-sensitive, Gi/o-biased, and bistable ciliary opsin from a fan worm | |
| 从头鉴定AlphaFold2模型中冷冻电镜断层扫描图的蛋白质结构域 | Lu, Y. | N/A | De novo identification of protein domains in cryo-electron tomography maps from AlphaFold2 models | |
| 通过机械反馈在菱脑神经孔形态发生中自我组织的细胞模式 | Perez-Verdugo, F. | N/A | Self-organized cell patterning via mechanical feedback in hindbrain neuropore morphogenesis | |
| Vγ9Vδ2TCR T细胞的敏感性是在早期癌变过程中通过单次突变后刻印下来的。 | Cleven, A. | N/A | Sensitivity to Vγ9Vδ2TCR T cells is imprinted after single mutations during early oncogenesis | |
| 在自发慢性结肠炎的温尼小鼠模型中，炎症进展与肌萎缩的并行研究 | Sharma, S. | N/A | Advancements in Inflammation Parallels Myopenia in Winnie Mice Model of Spontaneous Chronic Colitis | |
| 纵向血液微采样和蛋白质组监测有助于在实验性1型糖尿病中及时干预 | Parajuli, A. | N/A | Longitudinal blood microsampling and proteome monitoring facilitate timely intervention in experimental type 1 diabetes | |
| 实体瘤中介导巨噬细胞化学保护性生态位的空间组织：一项数学分析 | DANGELSER, W. | N/A | Spatial organization of mediated-macrophage chemoprotective niches in solid tumors: A mathematical analysis | |
| 在印度-缅甸生物多样性热点地区，形态相似的古热带螽斯科（Tettigoniidae）昆虫Mecopoda属的鸣声形态之间存在鸣声多样性。 | Ghosh, A. | N/A | Syntopic call diversity among morphologically similar calling morphs ofthe paleotropical katydid of genus Mecopoda (Tettigoniidae) from an Indo-Burma biodiversity hotspot. | |
| 期望违背作为一种有效的替代复杂心理化的新型沟通方式 | Buidze, T. | N/A | Expectation Violations as an Effective Alternative to Complex Mentalizing in Novel Communication | |
| 在线转向控制中的视觉惯性和视觉反馈 | Liu, J.-Y. | N/A | Visuoinertial and visual feedback in online steering control | |
| 抗体竞争对B细胞受体激活的调节 | He, Y. | N/A | Modulation of B cell receptor activation by antibody competition | |
| PI3Kδ活性丧失通过损害胸腺外Treg分化驱动自身免疫性结肠炎 | Lim, E. L. | N/A | Loss of PI3Kδ activity drives autoimmune colitis by impairing extrathymic Treg differentiation | |
| 卡波西肉瘤相关疱疹病毒解旋酶复合物成分ORF29的特性分析 | Iwaisako, Y. | N/A | Characterization of the Kaposi's sarcoma-associated herpesvirus terminase complex component ORF29 | |
| 从高保护到致命效果：使用不同白色念珠菌胞外囊泡进行侵袭性念珠菌病免疫接种的多样结果 | Martinez-Lopez, R. | N/A | From high protection to lethal effect: diverse outcomes of immunization against invasive candidiasis with different Candida albicans extracellular vesicles | |
| 谷氨酸-赖氨酸（EK）丰富的RabD2基序通过自相互作用并调控通过多泡体途径的致病性，在溶组织内阿米巴中发挥作用。 | Navyaka, P. | N/A | Glutamic acid-lysine (EK) rich motif of RabD2 self-associates and regulates pathogenesis through multivesicular bodies pathway in E. histolytica | |
| 在马基因组中搜索Jouvence SnoRNA | Peffers, M. J. | N/A | Searching for Jouvence SnoRNA in the Horse Genome | |
| 植物来源细胞外囊泡的真实参考标志物及其系统发育保守程度的综合概述 | Rodriguez de Lope, M. M. | N/A | A compendium of bona fide reference markers of plant-derived extracellular vesicles and their degree of phylogenetic conservation | |
| 实时成像：抗疟药物对感染恶性疟原虫的红细胞的影响 | Wallner, J. S. | N/A | Real-Time Imaging of Antimalarial Drug Effects on Plasmodium falciparum-Infected Red Blood Cells | |
| AI引导的体素提取和体积电镜识别出入侵位点为线粒体接触点 | Padman, B. S. | N/A | AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact | |
| 转录调控逻辑协调淋巴细胞和髓细胞命运决定 | Godini, R. | N/A | Transcriptional Regulatory Logic Orchestrating Lymphoid and Myeloid Cell Fate Decisions | |
| 肌萎缩侧索硬化症（ALS）和额颞叶痴呆（FTD）相关蛋白Annexin A11和CHMP2B在膜修复过程中依次发挥作用 | Heffner, C. M. | N/A | The ALS- and FTD-associated proteins Annexin A11 and CHMP2B act sequentially in membrane repair | |
| 昆虫肠道中的免疫启动：通过超微结构和转录组变化揭示的动态反应 | Baur, M. | N/A | Immune priming in the insect gut: a dynamic response revealed by ultrastructural and transcriptomic changes | |
| 真菌中附着染色体的水平转移——遗传物质交换的调控过程？ | Habig, M. | N/A | Horizontal transfer of accessory chromosomes in fungi - a regulated process for exchange of genetic material? | |
| 基因型与环境相互作用塑造泛素-蛋白酶体系统活性 | Avery, R. R. | N/A | Genotype-by-environment interactions shape ubiquitin-proteasome system activity | |
| 绿意T2T：散叶莴苣（Lactuca sativa var. crispa）端粒到端粒基因组组装与注释的升级版 | Zhang, B. | N/A | Green Elegance T2T: An upgraded telomere-to-telomere genome assembly and annotation of looseleaf lettuce (Lactuca sativa var. crispa) | |
| 风洞研究：海豚母子配对中的跟风力 | Weihs, D. | N/A | Wind Tunnel Study of the Forces Due to Drafting in Dolphin Mother-Calf pairs | |
| ConvCGP：一种卷积神经网络，用于从压缩的全基因组多态性预测水稻性状的基因型值 | Islam, T. | N/A | ConvCGP: A Convolutional Neural Network to Predict Genotypic Values of Rice Traits from Compressed Genome-Wide Polymorphisms | |
| 探索HLA在通过T细胞受体预测感染状态中的作用 | Ding, F. | N/A | Exploration of the Roles of HLAs When Predicting Infection Status by T Cell Receptors | |
| 从网络拓扑中揭示生化反应系统的分岔行为 | Huang, Y.-J. | N/A | Uncovering Bifurcation Behaviors of Biochemical Reaction Systems from Network Topology | |
| 激光闪熔冷冻电镜样品以克服择优取向 | Straub, M. S. | N/A | Laser Flash Melting Cryo-EM Samples to Overcome Preferred Orientation | |
| 三步前进：PTPN5的三种意外结构 | Guerrero, L. | N/A | Three STEPs forward: A trio of unexpected structures of PTPN5 | |
| 朝着鲁棒机器嗅觉迈进：去偏的GC-MS数据增强了从尿液挥发性物质中诊断前列腺癌的能力 | Rotteveel, A. | N/A | Towards robust machine olfaction: debiasing GC-MS data enhances prostate cancer diagnosis from urine volatiles | |
| 通过正电子发射断层扫描技术实现肿瘤微环境中pH变化的非侵入性可视化 | Brueck, J. | N/A | Non-invasive visualization of pH changes within the tumor-micro-environment by positron emission tomography | |
| 在研究心肌生物电活动变化中，使用深度学习算法进行微电极阵列电图的分割 | Kotikhina, E. | N/A | Use of deep learning algorithms for segmentation of microelectrode arrays electrograms in the study of changes in myocardial bioelectrical activity | |
| 一种复合亚单位疫苗在鼠足垫模型中对溃疡分枝杆菌感染提供了完全的保护，从而预防了布如里溃疡病。 | Boakye-Appiah, J. K. | N/A | A composite subunit vaccine confers full protection against Buruli ulcer disease in the mouse footpad model of Mycobacterium ulcerans infection | |
| 通过多组学揭示骨骼肌中内源性组织细胞外囊泡的功能异质性 | Wang, Y. | N/A | Unveiling the functional heterogeneity of endogenous tissue extracellular vesicles in skeletal muscle through multi-omics | |
| 单细胞荧光成像揭示了衰老生物标志物的异质性，并鉴定出雷帕霉素响应的亚群 | Seshadri, V. | N/A | Single-cell fluorescence imaging reveals heterogeneity in senescence biomarkers and identifies rapamycin-responsive sub-populations | |
| X染色体上的ARHGAP36基因位点的缺失与玳瑁猫和三花猫的橙色毛色有关。 | Toh, H. | N/A | A deletion at the X-linked ARHGAP36 gene locus is associated with the orange coloration of tortoiseshell and calico cats | |
| Hydractinia symbiolongicarpus中单一Helitron亚家族的扩展表明刺胞动物染色体扩展的共享机制 | Kon, T. | N/A | Expansion of a single Helitron subfamily in Hydractinia symbiolongicarpus suggests a shared mechanism of cnidarian chromosomal extension | |
| 人类存在与活动类型对城市欧亚红松鼠创新问题解决能力的影响。 | Chow, P. K. Y. | N/A | The Effect of Human Presence and Activity Type on Innovative Problem-Solving of Urban Eurasian Red Squirrels. | |
| 通过氧化还原途径对Sungouiella intermedia中乳糖和半乳糖代谢的模型驱动阐释，用于细胞工厂应用 | Peri, K. V. | N/A | Model-Driven Elucidation of Lactose and Galactose Metabolism via Oxidoreductive Pathway in Sungouiella intermedia for Cell Factory Applications | |
| 保守基团代谢流组学 | Fleming, R. M. | N/A | Conserved moiety fluxomics | |
| Trikafta通过加强特定的磷酸化依赖性域间相互作用，挽救了F508del-CFTR。 | Wang, G. | N/A | Trikafta rescues F508del-CFTR by tightening specific phosphorylation-dependent interdomain interactions | |
| CellBinDB：一个大规模多模态注释数据集，用于细胞分割，并包含通用模型的基准测试 | Shi, C. | N/A | CellBinDB: A Large-Scale Multimodal Annotated Dataset for Cell Segmentation with Benchmarking of Universal Models | |
| 共享节奏到共享愿景：同步行进提升感知决策中的从众行为 | Biswas, M. | N/A | Shared Rhythm to Shared Vision: Synchronous Marching increases Conformity on Perceptual Decision making | |
| 用于快速重定位波形蛋白中间丝的光遗传学和化学遗传学工具 | Pasolli, M. | N/A | Optogenetic and chemical genetic tools for rapid repositioning of vimentin intermediate filaments | |
| 西非几内亚比绍不同土地利用类型下的两栖动物和爬行动物数据集 | dos Reis-Silva, F. | N/A | Amphibian and reptile dataset across different land-use types in Guinea-Bissau, West Africa | |
| 致癌长链非编码RNA NEAT1在软与硬基质上的机械感知作用及其对胶质母细胞瘤进展的影响 | Ghosh, A. | N/A | Mechano-sensing role of oncogenic lncRNA NEAT1 on soft vs. stiff substrates and its implications for glioblastoma progression | |
| BAZ1A，一种模拟开关（ISWI）蛋白，与E2F1相互作用并促进其招募，以激活E2F转录程序。 | Prajapati, B. | N/A | BAZ1A, an Imitation Switch (ISWI) protein, interacts and facilitates the recruitment of E2F1 to activate the E2F transcription program | |
| 年龄相关的TREM1/2表达巨噬细胞的调控促进黑色素瘤进展和转移 | Scotegagna, M. | N/A | Age-associated modulation of TREM1/2- expressing macrophages promotes melanoma progression and metastasis | |
| 内在和外在机制改变EPM1癫痫中的神经细胞命运特化 | Forero, A. | N/A | Intrinsic and extrinsic mechanisms alter neural cell fate specification in EPM1 Epilepsy | |
| 轴突转录组揭示了PLK1的上调作为FUSP525L脊髓运动神经元中应对DNA损伤增加的保护机制 | Zimyanin, V. | N/A | Axonal transcriptome reveals upregulation of PLK1 as a protective mechanism in response to increased DNA damage in FUSP525L spinal motor neurons | |
| 刺豚鼠和BMP信号传导驱动斑马鱼中黑色素细胞向白色素细胞的自然发生的命运转换 | Huang, D. | N/A | Agouti and BMP signaling drive a naturally occurring fate conversion of melanophores to leucophores in zebrafish | |
| 多面体：高分辨率表位条形码用于体内空间命运图谱绘制 | Postrach, D. | N/A | Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping | |
| 在管状器官形成过程中顶端细胞外基质的组织 | Woodward, J. L. | N/A | Organization of the apical extracellular matrix during tubular organ formation | |
| Ox-LDL在人内皮细胞中诱导出一种富含冠状动脉疾病风险的非炎症反应 | Jiang, J. | N/A | Ox-LDL induces a non-inflammatory response enriched for coronary artery disease risk in human endothelial cells | |
| Beta-DIA：整合基于学习的和基于功能的特征评分，以优化单次diaPASEF质谱数据的蛋白质组学分析 | Song, J. | N/A | Beta-DIA: Integrating learning-based and function-based feature scores to optimize the proteome profiling of single-shot diaPASEF mass spectrometry data | |
| XAI-MRI：一种基于磁共振成像的3D脑肿瘤分割的集成双模态方法 | Farhan, A. S. | N/A | XAI-MRI: An Ensemble Dual-Modality Approach for 3D Brain Tumor Segmentation Using Magnetic Resonance Imaging | |
| 通过靶向伽马射线递送和卷积神经网络减轻化疗副作用：迈向精准肿瘤学的一步 | Siddiqui, S. | N/A | Mitigating Chemotherapy Side Effects through Targeted Gamma-Ray Delivery and Convolutional Neural Networks: A Step Toward Precision Oncology | |
| 破伤风类毒素通过靶向肿瘤唾液酸和增强细胞毒性CD4+ T细胞对胰腺癌的反应，利用双面抗癌机制 | Gupta, K. | N/A | Tetanus Toxoid Utilizes Dual-Faceted Anticancer Mechanism Through Targeting Tumoral Sialic Acids and Enhancing Cytotoxic CD4+ T cell Responses Against Pancreatic Cancer | |
| 异质性内分泌细胞组成定义了人类胰岛的功能表型 | Evans-Molina, C. | N/A | Heterogeneous endocrine cell composition defines human islet functional phenotypes | |
| 海岸红杉（Sequoia sempervirens）在整个分布范围内的非整倍体发生情况 | Nikolaeva, A. S. | N/A | Occurrence of Aneuploidy Across the Range of Coast Redwood (Sequoia sempervirens) | |
| 短期水分胁迫对大麦花药成熟过程中的形态和分子效应 | Lange, R. J. | N/A | Morphological and molecular effects of short-term water deficiency in barley stamen maturation | |
| 慢伽马和快伽马振荡在猕猴初级视觉皮层中显示出与不同高频带的相位-幅度耦合。 | Prabhu, P. | N/A | Slow and fast gamma oscillations show phase-amplitude coupling with distinct high-frequency bands in macaque primary visual cortex | |
| SIGNAL：用于语言的语义和推断语法神经分析的数据集 | Komissarenko, A. | N/A | SIGNAL: Dataset for Semantic and Inferred Grammar Neurological Analysis of Language | |
| 小脑和基底神经节的关联-边缘区域与感觉运动区域在显性情绪处理与隐性情绪处理中的不同参与度 | Ceravolo, L. | N/A | Differential Engagement of Associative-Limbic and Sensorimotor Regions of the Cerebellum and Basal Ganglia in Explicit vs. Implicit Emotional Processing | |
| 在有障碍物的情况下行走时，注视以抓住物体 | Voudouris, D. | N/A | Gaze when walking to grasp an object in the presence of obstacles | |
| 模拟两个输入具有不同共性的短期记忆的神经网络 | Raman, E. | N/A | Neural networks simulating short-term memory of two inputs with varying commonality | |
| 异性配对改变了雄性草原田鼠岛叶皮层中社会互动诱导的GCaMP和多巴胺活性 | Vitale, E. M. | N/A | Opposite-sex pairing alters social interaction-induced GCaMP and dopamine activity in the insular cortex of male prairie voles | |
| 果蝇黑腹果蝇（Drosophila melanogaster）湿度感受器在湿度依赖性下的结构适应 | Enjin, A. | N/A | Humidity-dependent structural adaptations of Drosophila melanogaster hygrosensilla | |
| 非空间网格状神经编码的发展预测了推理与智能 | Qu, Y. | N/A | Development of Non-Spatial Grid-Like Neural Codes Predicts Inference and Intelligence | |
| 星形胶质细胞特异性分泌组分析揭示其与神经疾病的关联 | Liu, J. | N/A | Astrocyte-specific secretome profiling reveals its correlation with neurological disorders | |
| 瞳孔测量与全脑c-Fos成像揭示了小鼠情绪传染网络中的多模态镜像机制 | Caldarelli, M. | N/A | Pupillometry and Whole-Brain c-Fos Mapping Uncover Multimodal Mirror Mechanisms in Emotional Contagion Networks of Mice | |
| 通过脑电图探索序数情感表征的神经基础和有效性 | Chen, X. | N/A | Exploring the Neural Basis and Validity of Ordinal Emotion Representation through EEG | |
| 人类大脑皮层中时间预期的神经特征反映了事件概率密度 | Grabenhorst, M. | N/A | Neural signatures of temporal anticipation in human cortex represent event probability density | |
| 在人类视网膜中以高空间和时间分辨率测量闪烁诱导的血管舒张。 | Senee, P. | N/A | Measuring flicker induced vasodilation at a high spatial and temporal resolution in the human retina. | |
| 兴奋性神经元中增强子上EGR1结合的升高与神经元亚型特异性的表观遗传调控相关 | Yin, L. | N/A | Elevated EGR1 Binding at Enhancers in Excitatory Neurons Correlates with Neuronal Subtype-Specific Epigenetic Regulation | |
| TRAIT：T细胞受体-抗原相互作用综合数据库 | Wei, M. | N/A | TRAIT: A Comprehensive Database for T-cell Receptor-Antigen Interactions | |
| 一种免疫机械检查点PYK2调控单核细胞向巨噬细胞的分化在胰腺癌中 | Xie, W. | N/A | An immunomechanical checkpoint PYK2 governs monocyte-to-macrophage differentiation in pancreatic cancer | |
| 通过T细胞中抗原的CAR内吞作用实现靶向蛋白质降解 | Peng, M. | N/A | Targeted protein degradation via CAR endocytosis of antigen in T cells | |
| 角质细胞暴露于急性和慢性蓝光下的阶段特异性表型和转录变化 | Tonolli, P. N. | N/A | Stage-specific phenotypic and transcriptional alterations in keratinocytes exposed to acute and chronic blue light | |
| PFAS化合物PFOA和Gen X对海胆胚胎具有致畸性。 | Lion, A. T. | N/A | PFAS Compounds PFOA and Gen X are Teratogenic to Sea Urchin Embryos | |
| 在妊娠初期对人类心脏图谱进行多模态细化 | De Bono, C. | N/A | Multi-modal refinement of the human heart atlas during the first gestational trimester | |
| 发育中的肠道中通过抑制性作用自组织形成的蠕动波图案 | Kawamura, K. | N/A | Self-organized patterning of peristaltic waves by suppressive actions in a developing gut | |
| 每日暴露于1.7 GHz LTE电磁场对早期胎儿大脑发育的影响：使用人脑皮质类器官模型进行的研究 | Park, G. Y. | N/A | Effect of the daily exposure of 1.7 GHz LTE electromagnetic field in early fetal brain development using a human brain organoid model of the cerebral cortex | |
| 人为噪音可能会通过阻碍蜜蜂介导的授粉过程，从而降低番茄的繁殖成功率。 | Varga-Szilay, Z. | N/A | Anthropogenic noise can decrease tomato reproductive success by hindering bumblebee-mediated pollination | |
| 在六种多细胞真核生物模型中，基因年龄越大，多效性越强。 | Martin, R. A. | N/A | Pleiotropy increases with gene age in six model multicellular eukaryotes | |
| TIRE-seq：一种集成样品提取与转录组学工作流程，用于高通量扰动研究 | O'Keeffe, P. | N/A | TIRE-seq: an Integrated Sample Extraction and Transcriptomics Workflow for High Throughput Perturbation Studies | |
| CTCF耗竭在细胞分化过程中将增强子介导的基因激活与染色质枢纽形成解耦 | Karpinska, M. A. | N/A | CTCF depletion decouples enhancer-mediated gene activation from chromatin hub formation during cellular differentiation | |
| 雌性鸣叫声引发Alston鸣鼠两性更强烈的鸣叫展示 | Tripp, J. A. | N/A | Female song elicits increased vocal display effort in both sexes of Alston's singing mouse | |
| 寻找路径：果蝇幼虫的局部搜索行为 | Kromp, J. | N/A | Finding a path: Local search behavior of Drosophila larvae | |
| 无菌条件下神经行为特征的评估：在同一只小鼠中进行多次纵向分析的方法。 | Rutsch, A. | N/A | Assessment of neurobehavioural traits under axenic conditions: an approach for multiple longitudinal analyses in the same mouse. | |
| SPO11依赖的双链断裂形成的重建 | Zheng, Z. | N/A | Reconstitution of SPO11-dependent double-strand break formation | |
| 细菌泛素样蛋白的结构多样性和寡聚化 | Gong, M. | N/A | Structural diversity and oligomerization of bacterial ubiquitin-like proteins | |
| 微生物物种树重建的系统评估 | Weiner, S. | N/A | A systematic assessment of phylogenomic approaches for microbial species tree reconstruction | |
| 超越整合：SuperGLUE促进多模态数据分析的可解释训练框架 | Liu, T. | N/A | Beyond Integration: SuperGLUE Facilitates Explainable Training Framework for Multi-modal Data Analysis | |
| 机器学习应用：预测含有非规范氨基酸的肽与HLA0201的结合亲和力 | Jiang, S. | N/A | Machine learning application to predict binding affinity between peptide containing non-canonical amino acids and HLA0201 | |
| TaxSEA：一个用于快速解读差异丰度分析结果的R包。 | Ryan, F. J. | N/A | TaxSEA: an R package for rapid interpretation of differential abundance analysis output. | |
| 红细胞的聚集与解聚：耗竭与桥接 | Moreno, N. | N/A | Aggregation and disaggregation of red blood cells: depletion versus bridging | |
| 一种tau-紫杉醇竞争的地板场模型解释了紫杉醇稳定微管上的tau包膜动力学 | Chevalier, C. | N/A | A floor-field model of tau-taxol competition explains tau envelope dynamics on taxol-stabilized microtubules | |
| 靶向黑色素瘤中依赖eIF4G1的翻译 | Feng, Y. | N/A | Targeting eIF4G1-dependent translation in melanoma | |
| Ezh2在正常小脑颗粒神经元发育和髓母细胞瘤中延迟分化基因的激活 | Purzner, J. | N/A | Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma | |
| 描述转移性癌症迁移历史解空间的特征：MACH2 | Roddur, M. S. | N/A | Characterizing the Solution Space of Migration Histories of Metastatic Cancers with MACH2 | |
| Rho GTPase信号传导介导了神经母细胞瘤肿瘤的侵袭性和分化 | Gomez-Munoz, M. A. | N/A | Rho GTPases signaling mediates aggressiveness and differentiation in neuroblastoma tumors | |
| 超小颗粒纳米气泡水饮用通过改善抗氧化活性对慢性运动疲劳大鼠产生抗疲劳作用 | Qi, J. | N/A | Ultra-small Particle Size Nanobubbles Water Drinking Exerts Antifatigue Effects in Chronic Exercise Fatigue Rats via Improving Antioxidative Activities | |
| 一种新发现的拟南芥蛋白，ABAP1相互作用蛋白10，介导了细胞周期与初级代谢之间的交叉对话 | MONTESSORO, P. | N/A | A novel Arabidopsis thaliana protein, ABAP1 INTERACTING PROTEIN 10, mediates crosstalk between the cell cycle and primary metabolism | |
| 大麦对真菌细胞侵入的抗性和易感性涉及ROP信号与磷脂酰肌醇单磷酸之间的相互作用。 | Weiss, L. S. | N/A | Barley resistance and susceptibility to fungal cell entry involve the interplay of ROP signaling with phosphatidylinositol-monophosphates | |
| 无抗生素全细胞生物催化发酵：表面展示PETase的工程大肠杆菌用于可持续塑料降解 | Romero-Orejon, K. | N/A | Antibiotic-free whole-cell biocatalytic fermentation: Escherichia coli with surface-displayed PETases for sustainable plastic degradation | |
| 人类屏状核在多种认知任务中被激活 | Huang, C. H. L. | N/A | The human claustrum activates across multiple cognitive tasks | |
| 语义整合需求调节大脑大规模网络交互 | Nieberlein, L. | N/A | Semantic integration demands modulate large-scale network interactions in the brain | |
| 负载CSF1R拮抗剂的纳米颗粒可选择性耗竭小胶质细胞，并调节脊髓损伤中的炎症反应。 | Yang, J. | N/A | Nanoparticles loaded with a CSF1R antagonist selectively depletes microglial cells and modulates inflammation in spinal cord injury | |
| 帕金森病中感觉运动皮层-丘脑下核回路的Beta爆发特征及其耦合关系 | Yao, P. | N/A | Beta burst characteristics and coupling within the sensorimotor cortical-subthalamic nucleus circuit in Parkinson's disease | |
| 由Rab39调控的Atg9顺行运输介导的突触自噬的以Soma为中心的调控 | Kilic, A. | N/A | Soma-centered control of synaptic autophagy by Rab39-regulated anterograde trafficking of Atg9 | |
| 双特异性磷酸酶1（DUSP1）在调节由伯氏疏螺旋体脂蛋白调控的巨噬细胞炎症通路中的作用 | Kumaresan, V. | N/A | Role of Dual Specificity Phosphatase 1 (DUSP1) in influencing inflammatory pathways in macrophages modulated by Borrelia burgdorferi lipoproteins | |
| 树突状细胞通过嵌合突触促进CAR T细胞在放射治疗后的肿瘤中的加速作用 | Navarre, S. | N/A | Dendritic cells accelerate CAR T cells in irradiated tumors through chimeric synapses | |
| 在持续人为压力下，城市微生物群落向产生类胡萝卜素物种转变。 | Sedova, V. V. | N/A | Urban microbial communities shift towards carotenoid-producing species under constant anthropogenic stress | |
| 多重PCR技术用于测量实验性尿路感染期间尿路致病性大肠杆菌的原位生长速率。 | Paudel, S. | N/A | Multiplexed PCR to measure in situ growth rates of uropathogenic E. coli during experimental urinary tract infection. | |
| Dickeya dadantii 3937 产生 P2D1 尾菌素：胁迫启动、基因表达与活性粒子浓度之间的时间关系 | Sobolewska, M. | N/A | Production of P2D1 tailocins by Dickeya dadantii 3937: a temporal relationship between the stressor onset, gene expression, and the concentration of active particles | |
| 从人类鼻腔和皮肤分离出的两种新型棒状杆菌属物种的描述 | Popowitch, E. B. | N/A | Description of two novel Corynebacterium species isolated from human nasal passages and skin | |
| TcCARP3调节了与渗透调节、哺乳动物细胞感染以及人类病原体克鲁斯锥虫在锥蝽媒介中定殖相关的区室化cAMP信号。 | Carlson, J. | N/A | TcCARP3 modulates compartmentalized cAMP signals involved in osmoregulation, infection of mammalian cells, and colonization of the triatomine vector in the human pathogen Trypanosoma cruzi | |
| 亚治疗浓度的抗生素在铜绿假单胞菌中诱导了前噬菌体驱动的超感染排斥和适应性代价 | Bucher, M. J. | N/A | Sub-therapeutic Concentrations of Antibiotics Induce Prophage-driven Superinfection Exclusion and Fitness Cost in Pseudomonas aeruginosa | |
| 钙调神经磷酸酶抑制剂会抑制丙酮酸脱氢酶的活性，并导致近端小管细胞的代谢功能障碍，从而引发促纤维化表型。 | Oda, Y. | N/A | Calcineurin inhibition deactivates pyruvate dehydrogenase and induces proximal tubule cell metabolic dysfunction, causing profibrotic phenotype | |
| 发育中的羽毛细胞类型的遗传特征及其复杂性的演化 | Limber, C. | N/A | Genetic Characterization of the Cell Types of in Developing Feathers, and the Evolution of Feather Complexity | |
| 大肠杆菌中增加乙酸代谢的代谢权衡 | Pentz, J. T. | N/A | Metabolic trade-offs in response to increased acetate metabolism in Escherichia coli | |
| 海蜘蛛的基因组证实了节肢动物中减少的后部体节共享的Hox集群模式。 | Papadopoulos, N. | N/A | The genome of a sea spider corroborates a shared Hox cluster motif in arthropods with reduced posterior tagma | |
| 通过甲醛固定、冷冻保存和多重化技术增强单细胞ATAC测序，以实现灵活分析 | Hohl, T. | N/A | Enhancing single-cell ATAC sequencing with formaldehyde fixation, cryopreservation, and multiplexing for flexible analysis | |
| 双功能伴侣蛋白中可切换的客户端特异性协调光捕获复合物的生物合成 | Siegel, A. R. | N/A | Switchable client specificity in a dual functional chaperone coordinates light harvesting complex biogenesis | |
| 在分化细菌泛素化途径中蛋白质偶联的机制基础 | Ye, Q. | N/A | Mechanistic basis for protein conjugation in a diverged bacterial ubiquitination pathway | |
| 可溶性细菌视紫红质的工程改造 | Nikolaev, A. | N/A | Engineering of soluble bacteriorhodopsin | |
| 用于活细胞中灵敏且同时成像不同单个mRNA的RNA稳定化外壳蛋白 | Kuffner, C. J. | N/A | RNA-Stabilized Coat Proteins for Sensitive and Simultaneous Imaging of Distinct Single mRNAs in Live Cells | |
| 使用行-列阵列在离体心室心肌的双轴测试期间进行三维组织应变测量 | Navy, X. | N/A | Three-dimensional tissue strain measurement using a row-column array during biaxial testing of excised ventricular myocardium | |
| Alphafold2 优化提升了大型从头设计蛋白质的可设计性 | Frank, C. J. | N/A | Alphafold2 refinement improves designability of large de novo proteins | |
| FocalSV：基于目标区域的结构变异组装与优化，利用单分子长读长测序数据 | Luo, C. | N/A | FocalSV: target region-based structural variant assembly and refinement using single-molecule long read sequencing data | |
| RobustCell：一种用于稳健转录组数据分析的模型攻击防御框架 | Liu, T. | N/A | RobustCell: A Model Attack-Defense Framework for Robust Transcriptomic Data Analysis | |
| 相邻转录因子在DNA上结合的协同性的定量分析及其潜在功能相关性 | Wang, X. | N/A | Quantification and potential functional relevanceof binding cooperativity of adjacent transcriptionfactors on DNA | |
| 甲硫氨酸代谢、DNA修复与胶质母细胞瘤中的治疗抵抗之间的相互联系 | Korimerla, N. | N/A | Reciprocal links between methionine metabolism, DNA repair and therapy resistance in glioblastoma | |
| 使用mRNA-LNPs生成的CAR-NK细胞有效靶向CD19阳性原发性B-ALL细胞 | Salehi-Shadkami, H. | N/A | Effective targeting of CD19 positive primary B-ALL cells using CAR-NK cells generated with mRNA-LNPs | |
| 肝肾有机阳离子转运体对西咪替丁-二甲双胍临床药代动力学相互作用的定量贡献 | Ailabouni, A. S. | N/A | Quantitative contributions of hepatic and renal organic cation transporters to the clinical pharmacokinetic cimetidine-metformin interaction | |
| 自然历史藏品数据的动员可以提高生物多样性信息的质量和覆盖范围。 | Blades, B. | N/A | Mobilisation of data from natural history collections can increase the quality and coverage of biodiversity information | |
| 下丘脑室旁核和视上核中的催产素神经元双向调节食物摄入。 | Rea, J. J. | N/A | Oxytocin neurons in the paraventricular and supraoptic hypothalamic nuclei bidirectionally modulate food intake | |
| 皮层慢波的全球性和局部性 | Alegre-Cortes, J. | N/A | Global and local nature of cortical slow waves | |
| 少突胶质细胞的区域异质性决定了兰维尔结在声音定位电路中单个轴突上的偏倚分布模式。 | Egawa, R. | N/A | Regional heterogeneities of oligodendrocytes determine biased distribution pattern of Ranvier nodes along single axons in sound localization circuit | |
| 机器学习识别出与马脑炎病毒（EEV）、创伤性脑损伤（TBI）和有机磷神经毒剂（OPNA）引起神经疾病相关的基因 | Yin, L. | N/A | Machine Learning Identifies Genes Linked to Neurological Disorders Induced by Equine Encephalitis viruses (EEV), Traumatic Brain Injuries (TBI), and Organophosphorus nerve agents (OPNA) | |
| 单剂量禽流感A(H5N1)谱系2.3.4.4b血凝素-基质-M纳米颗粒疫苗在非人灵长类动物中诱导中和反应 | Patel, N. | N/A | Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin-Matrix-M nanoparticle vaccine induces neutralizing responses in nonhuman primates | |
| 一种用于定量噬菌体病毒载体滴度和纯度的数字PCR检测方法。 | Voorhees, P. J. | N/A | A Droplet Digital PCR Assay for Quantification of Bacteriophage Viral Vector Titer and Purity. | |
| 使用缺乏病毒致病基因的复制缺陷型鼠γ疱疹病毒进行疫苗接种可抑制野生型病毒感染 | Mitra, D. | N/A | Vaccination with a Replication-Dead Murine Gammaherpesvirus Lacking Viral Pathogenesis Genes Inhibits WT Virus Infection | |
| 在随机组装过程中，微生物群落内部和之间的多样性驱动因素 | Marrec, L. | N/A | Drivers of diversity within and between microbialcommunities during stochastic assembly | |
| 单一的高锌激活增强剂可以在秀丽隐杆线虫中控制两个头对头排列的基因 | Liu, H. | N/A | A single high-zinc activation enhancer can control two genes oriented head-to-head in C. elegans | |
| 加压素V2受体的非活性结构揭示了Tolvaptan和Mambaquaretin毒素的不同拮抗剂结合模式 | Fouillen, A. | N/A | Inactive structures of the vasopressin V2 receptor reveal distinct antagonist binding modes for Tolvaptan and Mambaquaretin toxin | |
| 慢性神经性疼痛状态对芬太尼及其他μ受体激动剂的辨别性刺激效应的影响 | Burgess, G. E. | N/A | The effects of chronic neuropathic pain states on the discriminative stimulus effect of fentanyl and other MOR agonists | |
| 来自Amphitrite ornata的多功能催化血红蛋白：分离、分类鉴定、蛋白质提取、纯化及表征的操作流程 | Husted, A. L. | N/A | The Multifunctional Catalytic Hemoglobin from Amphitrite ornata: Protocols on Isolation, Taxonomic Identification, Protein Extraction, Purification, and Characterization | |
| 生长依赖性调节Gin4激酶的机制 | Diaz, F. M. | N/A | Mechanisms of growth-dependent regulation of the Gin4 kinase | |
| 淀粉质体对于地钱（Marchantia polymorpha）叶状体的完全向重力性反应是必需的。 | Hashimoto-Sugimoto, M. | N/A | Amyloplasts are necessary for full gravitropism in thallus of Marchantia polymorpha | |
| 瞬时组蛋白去乙酰化酶抑制可诱导基因表达的细胞记忆及三维基因组折叠 | Paldi, F. | N/A | Transient histone deacetylase inhibition induces cellular memory of gene expression and three-dimensional genome folding | |
| # BioRxiv 2024-11-20 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| JNK MAPK 调控化学耐药性、静止白血病细胞中的 IFN 刺激基因和细胞粘附 | Lee, S. | N/A | JNK MAPK Regulates IFN-Stimulated Genes and Cell Adhesion in Chemoresistant, Quiescent Leukemic Cells | |
| 好妈妈：平原斑马中的依赖幼崽及其母亲比其他个体更能适应较长的旱季 | Thel, L. | N/A | Good moms: dependent-young and their mothers cope better than others with longer dry season in plains zebras | |
| SUMO激活酶亚单位SAE2对有丝分裂保真性中的SUMO蛋白偏向性有贡献。 | Walker, A. | N/A | The SUMO activating enzyme subunit, SAE2, contributes SUMO protein bias for mitotic fidelity. | |
| 淋巴结成纤维细胞表型及由Podoplanin活性调控的免疫交叉对话 | Makris, S. | N/A | Lymph node fibroblast phenotypes and immune crosstalk regulated by Podoplanin activity | |
| 使用dreamlet进行大规模单细胞转录组数据的高效差异表达分析 | Hoffman, G. E. | N/A | Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet | |
| N6-甲基腺苷（m6A）促进具有完整5'剪接位点基序的mRNA在细胞核中的保留 | Lee, E. S. | N/A | N-6-methyladenosine (m6A) Promotes the Nuclear Retention of mRNAs with Intact 5' Splice Site Motifs | |
| 农药诱导的褐飞虱再猖獗是通过影响一系列促进保幼激素生物合成和雌性生殖力的基因而介导的。 | Gao, Y. | N/A | Pesticide-induced resurgence in brown planthopper is mediated by action on a suite of genes that promote juvenile hormone biosynthesis and female fecundity | |
| APOBEC3活性促进肺癌中获得性耐药EGFR抑制剂期间耐药持久细胞的存活和进化 | Garcia, N. M. G. | N/A | APOBEC3 activity promotes the survival and evolution of drug-tolerant persister cells during acquired resistance to EGFR inhibitors in lung cancer | |
| 中介激酶抑制剂抑制唐氏综合征中过度活跃的干扰素信号传导 | Cozzolino, K. | N/A | Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome | |
| 在自然音乐聆听过程中映射多模态动态网络活动 | Faber, S. E. | N/A | Mapping multi-modal dynamic network activity during naturalistic music listening | |
| 高置信度糖体膜蛋白清单揭示了锥虫中的过氧化物酶体蛋白PEX15 | Krishna, C. K. | N/A | High confidence glycosomal membrane protein inventory unveils trypanosomal Peroxin PEX15 | |
| 在运动执行和运动规划过程中，控制策略可以根据任务需求进行调整。 | Orban de Xivry, J.-J. | N/A | A control policy can be adapted to task demands during both motor execution and motor planning | |
| Oct4 与 Sox2 之间的新兴协同作用调控着早期小鼠胚胎中的多能性网络。 | Hou, Y. | N/A | Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in early mouse embryos | |
| 评估不同突变发现方法之间的不一致体细胞突变，以最大限度减少假阴性耐药性发现 | Lin, H.-F. | N/A | Evaluating discordant somatic calls across mutation discovery approaches to minimize false negative drug-resistant findings | |
| 基于电导的神经元模型中高去极化基线偏移的机制与意义 | Kumar, A. | N/A | Mechanisms and implications of high depolarization baseline offsets in conductance-based neuronal models | |
| 共受体Tetraspanin12直接捕获Norrin以促进配体特异性的β-连环蛋白信号传导 | Bruguera, E. S. | N/A | The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling | |
| 全球多样性与进化：巴拿马沙门氏菌——一种全球范围内引起胃肠道和侵袭性疾病但研究不足的血清型：一项基因组流行病学研究 | Pulford, C. V. | N/A | Global diversity and evolution of Salmonella Panama, an understudied serovar causing gastrointestinal and invasive disease worldwide: a genomic epidemiology study | |
| 白血病的侵袭性受染色质重塑和核心调控因子表达变化所驱动。 | Bonilla, G. | N/A | Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators | |
| 在视觉-正字法预测误差表征中指定精度，以更好地理解高效阅读 | Fu, W. | N/A | Specifying precision in visual-orthographic prediction error representations for a better understanding of efficient reading | |
| 蜜蜂嗉囊中的细菌与花蜜和蜜蜂口腔中的细菌不相关。 | Warren, M. L. | N/A | Bacteria in honeybee crops are decoupled from those in floral nectar and bee mouths | |
| 成年神经发生协调了嗅觉感知记忆的灵活性和稳定性 | Sakelaris, B. | N/A | Adult Neurogenesis Reconciles Flexibility and Stability of Olfactory Perceptual Memory | |
| 性染色体的进化与物种形成的两个规则的单一理论 | Lenormand, T. | N/A | A single theory for the evolution of sex chromosomes and the two rules of speciation | |
| 动物物种间SARS-CoV-2的宿主内遗传多样性 | Naderi, S. | N/A | Within-host genetic diversity of SARS-CoV-2 across animal species | |
| 不同的秀丽隐杆线虫毒素等位基因通过不同的机制被抑制 | Zdraljevic, S. | N/A | Divergent C. elegans toxin alleles are suppressed by distinct mechanisms | |
| CetZ1依赖的极性运动机器在嗜盐古菌中的组装 | Brown, H. J. | N/A | CetZ1-dependent polar assembly of the motility machinery in haloarchaea | |
| MYB68调控径向内胚层分化及木栓质模式形成 | Kraska, L. | N/A | MYB68 regulates radial endodermal differentiation and suberin patterning | |
| KCa3.1的早期新型精氨酸甲基化减弱了后续T细胞的耗竭。 | Sharma, P. | N/A | An early, novel arginine methylation of KCa3.1 attenuates subsequent T cell exhaustion. | |
| 降低腹内侧下丘脑（VMH）中神经型一氧化氮合酶（nNOS）的表达会增加雌性小鼠的体重和血糖水平，同时降低其身体活动。 | Hirschberg, P. R. | N/A | Reducing neuronal nitric oxide synthase (nNOS) expression in the ventromedial hypothalamus (VMH) increases body weight and blood glucose levels while decreasing physical activity in female mice. | |
| 可扩展、高质量工程化干细胞衍生的SIRPα-细胞外囊泡的双模态作用治疗急性肝衰竭 | Kim, S. | N/A | Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure | |
| 控制Ins2基因活性和β细胞状态转换的信号转导通路 | Chu, J. | N/A | Signal transduction pathways controlling Ins2 gene activity and β cell state transitions | |
| 鉴定用于神经退行性疾病治疗的新型小分子伴侣激活剂 | Ho, A. | N/A | Identification of novel small molecule chaperone activators for neurodegenerative disease treatment | |
| 食管腺癌的化生前体状态代表了在发育中的食管中向短暂的上皮细胞状态的逆转。 | Baker, S. | N/A | The metaplastic precursor state to oesophageal adenocarcinoma represents reversion to a transient epithelial cell state in the developing oesophagus | |
| 人类新生儿超越词汇的统计学习 | Flo, A. | N/A | Statistical learning beyond words in human neonates | |
| 克服毒性：为何繁荣与衰退周期对非对抗性微生物有益 | Wang, M. | N/A | Overcoming toxicity: why boom-and-bust cycles are good for non-antagonistic microbes | |
| 鳃组织活检的转录组分析以确定养殖大西洋鲑鱼海水存活率的预测标志物 | Gronvold, L. | N/A | Transcriptomic profiling of gill biopsies to define predictive markers for seawater survival in farmed Atlantic salmon | |
| 增殖事件改善了造血干细胞中DNA损伤的积累，而不影响其功能。 | Mehatre, S. H. | N/A | Proliferative events ameliorate DNA damage accumulation without affecting function in hematopoietic stem cells | |
| 物体非刚性的各向异性：皮层各向异性对高级感知的影响 | Maruya, A. | N/A | Anisotropy of object nonrigidity: High-level perceptual consequences of cortical anisotropy | |
| 本科生研究学生使用的ChatGPT辅助阅读协议 | Sambar, M. | N/A | A ChatGPT Assisted Reading Protocol for Undergraduate Research Students | |
| 结构引导的循环嫁接技术提高了流感神经氨酸酶在疫苗开发中的表达和稳定性 | Rijal, P. | N/A | Structure-Guided Loop Grafting Improves Expression and Stability of Influenza Neuraminidase for Vaccine Development | |
| 一种流行性Ralstonia solanacearum谱系的兴起及其宿主范围的扩展 | Evseeva, D. | N/A | Emergence and host range expansion of an epidemic lineage of Ralstonia solanacearum | |
| 使用稳定同位素示踪法建模复合脂质稳态 | Wessendorf-Rodriguez, K. | N/A | Modeling Compound Lipid Homeostasis Using Stable Isotope Tracing | |
| 在主要外排敲除系统中确定铜绿假单胞菌MexXY-OprM底物谱，揭示了不同的抗生素底物类别 | Kavanaugh, L. G. | N/A | Determination of Pseudomonas aeruginosa MexXY-OprM substrate profile in a major efflux knockout system reveals distinct antibiotic substrate classes | |
| 基于纵向微生物组的可解释机器学习用于早期疾病结果预测中时变生物标志物的识别 | Dai, Y. | N/A | Longitudinal Microbiome-based Interpretable Machine Learning for Identification of Time-Varying Biomarkers in Early Prediction of Disease Outcomes | |
| 罕见癌症靶点发现框架 | Li, B. | N/A | A framework for target discovery in rare cancers | |
| 生物医学数据的AI准备：Bridge2AI建议 | Clark, T. | N/A | AI-readiness for Biomedical Data: Bridge2AI Recommendations | |
| 听觉皮层中的正交频谱和时间包络表示 | Takahashi, K. | N/A | Orthogonal spectral and temporal envelope representation in auditory cortex | |
| 海葵生命史中基质分子动力学 | Bergheim, B. G. | N/A | Molecular dynamics of the matrisome across sea anemone life history | |
| 神经肌肉骨骼建模流程：基于MATLAB的OpenSim模型个性化与治疗优化功能 | Hammond, C. V. | N/A | The Neuromusculoskeletal Modeling Pipeline: MATLAB-based Model Personalization and Treatment Optimization Functionality for OpenSim | |
| 定义细胞类型特异性CTCF结合和染色质组织的基因组范围代码 | Do, C. | N/A | A genome wide code to define cell-type specific CTCF binding and chromatin organization | |
| 微生物群落中的对抗作为一种觅食策略 | Stubbusch, A. K. M. | N/A | Antagonism as a foraging strategy in microbial communities | |
| 脊椎动物R2逆转录转座子复合物在目标引导逆转录期间的结构及第二链切割后的结构 | Thawani, A. | N/A | Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nicking | |
| 通过结构建模和分歧日期估算，理解植物和真菌病毒中RNA聚合酶的进化和功能关系 | Gracy, J. | N/A | Understanding evolutionary and functional relationships of RNA polymerases in plant and fungal viruses through structural modeling and divergence date estimations | |
| 对玉米驯化过程中根系表型在特瓦坎新石器时代土壤中的演变进行计算机模拟分析 | Lopez-Valdivia, I. | N/A | In silico analysis of the evolution of root phenotypes during maize domestication in Neolithic soils of Tehuacan | |
| 基于结冷胶的营养培养基增加了土壤微生物培养群的多样性 | Kulikova, D. | N/A | Gellan gum-based nutrient medium increases the diversity of cultivated groups of soil microorganisms | |
| 与越南H5N1分离株相比，牛H5N1在小鼠中表现出增强的脑炎趋向性。 | Goldin, K. | N/A | Enhanced encephalitic tropism of bovine H5N1 compared to the Vietnam H5N1 isolate in mice | |
| 磁共振R2*捕捉中风后不连续脑结构中的炎症：一项转化研究 | Koubiyr, I. | N/A | MRI R2* captures inflammation in disconnected brain structures after stroke: a translational study | |
| 在BSL2级别下，使用直接薄层琼脂进行结核分枝杆菌对贝达喹啉的敏感性测试，从痰液处理开始15天内可获得高准确性。 | Cuella Martin, I. | N/A | Direct thin-layer agar for bedaquiline-susceptibility testing of Mycobacterium tuberculosis at BSL2 level yields high accuracy in 15 days from sputum processing. | |
| 野生大麦多样性全基因组测序：用于鉴定和利用遗传变异以改良栽培大麦的资源 | Sallam, A. H. | N/A | Whole-Genome Sequencing of the Wild Barley Diversity Collection: A Resource for Identifying and Exploiting Genetic Variation for Cultivated Barley Improvement | |
| 基于基因表达的膀胱癌淋巴结转移预测因子评估 | Johansson, H. B. | N/A | Evaluation of gene expression-based predictors of lymph node metastasis in bladder cancer | |
| 委内瑞拉十一种无尾两栖动物的体型变异与性二态性 | Canizales, I. | N/A | Body Size Variation And Sexual Dimorphism In Eleven Species Of Venezuelan Anurans | |
| 分子脑老化新多基因风险评分的神经结构和认知特征 | Clifford, K. P. | N/A | Neurostructural and cognitive signatures of novel polygenic risk scores for molecular brain aging | |
| 内源性LINE-1蛋白及ORF2p相互作用的靶向检测 | Nielsen, M. I. | N/A | Targeted detection of endogenous LINE-1 proteins and ORF2p interactions | |
| Nano3P-seq：以单分子分辨率绘制编码和非编码转录组图谱 | Begik, O. | N/A | Nano3P-seq: charting the coding and non-coding transcriptome at single molecule resolution | |
| SuperWater：利用生成式AI预测蛋白质结构上的水分子位置 | Kuang, X. | N/A | SuperWater: Predicting Water Molecule Positions on Protein Structures by Generative AI | |
| 通过抑制或降解LZK来靶向GOF p53和c-MYC抑制头颈肿瘤生长 | Funk, A. L. | N/A | Targeting GOF p53 and c-MYC through LZK Inhibition or Degradation Suppresses Head and Neck Tumor Growth | |
| 发育程序中的重复超基序电路 | Adler, M. | N/A | Recurrent hyper-motif circuits in developmental programs | |
| AZIN2依赖的多胺代谢决定脂肪细胞前体细胞的命运，并保护机体免受肥胖和代谢紊乱的影响。 | Mund, C. | N/A | AZIN2-dependent polyamine metabolism determines adipocyte progenitor fate and protects against obesity and dysmetabolism | |
| 冰滑硅藻创下了真核细胞运动最低温度限制的纪录 | Zhang, Q. | N/A | Ice gliding diatoms establish record-low temperature limit for motility in a eukaryotic cell | |
| Boltz-1：使生物分子相互作用建模民主化 | Wohlwend, J. | N/A | Boltz-1: Democratizing Biomolecular Interaction Modeling | |
| 修改聚集状态可能会提高Ozempic的活性。 | Bolano Alvarez, A. | N/A | Modifying the aggregation state may improve the activity of Ozempic | |
| 片状伪足中动态稳态的机制 | Kim, J. H. | N/A | The Mechanism of Dynamic Steady States in Lamellipodia | |
| 细胞分裂过程中染色体形态的渐进变化，通过环捕获模拟再现 | Kakui, Y. | N/A | Progressive chromosome shape changes during cell divisions, recapitulated by loop capture simulations | |
| 通过细胞内丝状体感知表面形状 | Shi, H. | N/A | Sensing the shape of a surface by intracellular filaments | |
| 分枝杆菌脂阿糖甘露聚糖负向干扰巨噬细胞对烟曲霉的体外反应 | Gonzales-Huerta, L. E. | N/A | Mycobacterial lipoarabinomannan negatively interferes with macrophage responses to Aspergillus fumigatus in-vitro | |
| 精氨酸调控超毒力肺炎克雷伯菌的黏液表型 | Ring, B. E. | N/A | Arginine Regulates the Mucoid Phenotype of Hypervirulent Klebsiella pneumoniae | |
| 学习单细胞转录组数据的多细胞表示，有助于表征患者层面的疾病状态。 | Liu, T. | N/A | Learning multi-cellular representations of single-cell transcriptomics data enables characterization of patient-level disease states | |
| 外周来源巨噬细胞的命运图谱揭示，在创伤性脑损伤后长达8个月的时间里，存在一群持久植入的细胞，这些细胞维持着独特的转录组特征。 | Paladini, M. S. | N/A | Fate mapping of peripherally derived macrophages reveals a long-lasting engrafted population that maintains a distinct transcriptomic profile for up to 8 months after Traumatic Brain Injury | |
| 根瘤菌能否缓解豆科植物受到气候介导的微生物群落效应的影响？ | Boyle, J. A. | N/A | Do rhizobia buffer legumes against climate-mediated microbiome effects? | |
| 揭示隐藏的盛宴：将分子检测转化为捕食率——农业生态系统中广食性捕食者生物防治的一个实例。 | MASSON, A. L. | N/A | Unveiling the Hidden Feast: translating molecular detection into predation rate. An example on biological control by generalist predators in agricultural fields. | |
| 伊维菌素残留对粪便昆虫的依赖于环境背景的影响：与环境压力源、体型和性别在一种腐蝇（Sepsis neocynipsea）中的相互作用 | Walker, J. | N/A | Context-dependent effects of ivermectin residues on dung insects: Interactions with environmental stressors, size, and sex in a sepsid fly (Sepsis neocynipsea) | |
| 关于非随机交配、适应性进化与信息论 | Carvajal-Rodriguez, A. | N/A | On non-random mating, adaptive evolution and information theory | |
| 行波划动在雷诺数变化四个数量级的情况下仍能提供强大的推进性能。 | Ford, M. P. | N/A | Metachronal rowing provides robust propulsive performance across four orders of magnitude variation in Reynolds number | |
| 利用AlphaFold 3进行神经疾病相关蛋白质的结构建模：通向精准医学的路径 | Gadde, N. | N/A | Leveraging AlphaFold 3 for Structural Modeling of Neurological Disorder-Associated Proteins: A Pathway to Precision Medicine | |
| 使用向量符号架构进行特征选择：结直肠癌 shotgun 宏基因组样本微生物特征的案例研究 | Cumbo, F. | N/A | Feature selection with vector-symbolic architectures: a case study on microbial profiles of shotgun metagenomic samples of colorectal cancer | |
| 原子模拟揭示线粒体ATP合酶中ATP酶抑制因子1的旋转方向依赖性调控 | Kobayashi, R. | N/A | Rotation-direction-dependent regulation of ATPase inhibitory factor 1 for mitochondrial ATP synthase from atomistic simulation | |
| 癌症相关DAXX突变揭示了ATRX定位在ALT抑制中的关键作用 | Clatterbuck Soper, S. F. | N/A | Cancer-associated DAXX mutations reveal a critical role for ATRX localization in ALT suppression | |
| 网络毒理学聚焦研究无机砷和镉对人类和生态系统健康的影响 | Chivukula, N. | N/A | Network toxicology focused investigation on the impacts of inorganic arsenic and cadmium on human and ecosystem health | |
| Sigma配体介导的BV2小胶质细胞胞质钙调制 | Lodholz, E. | N/A | Sigma Ligand-mediated Cytosolic Calcium Modulation in BV2 Microglia Cells | |
| 一个TORC1-PHR1信号轴调控拟南芥中的磷饥饿与免疫信号网络 | Awasthi, P. | N/A | A TORC1-PHR1 signaling axis regulates phosphorus starvation and immunity signaling network in Arabidopsis | |
| 转录反终止作用整合了在嵌合的巴尔通体基因转移因子BaGTA中源自不同噬菌体基因座的表达 | Korotaev, A. | N/A | Transcriptional antitermination integrates the expression of loci of diverse phage origin in the chimeric Bartonella Gene Transfer Agent BaGTA | |
| 优化从鼻腔衬液中提取DNA以使用第三代测序评估鼻腔微生物群 | Montgomery, S. T. | N/A | Optimisation of DNA extraction from nasal lining fluid to assess the nasal microbiome using third-generation sequencing | |
| 丝状化图谱揭示了几个转录调控因子，这些因子导致了白色念珠菌和都柏林念珠菌之间的差异。 | Meza-Davalos, T. | N/A | Filamentation profile reveals several transcription regulators that contribute to differences between Candida albicans and Candida dubliniensis | |
| 人巨细胞病毒pp65的蛋白质-S-亚硝基化降低了其削弱cGAS的能力。 | Cox, J. B. | N/A | Protein-S-Nitrosylation of Human Cytomegalovirus pp65 Reduces its Ability to Undermine cGAS. | |
| 通过灵活的顺反相互作用快速重塑古菌转录因子功能 | Martinez-Pastor, M. | N/A | Rapid rewiring of an archaeal transcription factor function via flexible cis-trans interactions | |
| JN.1单价mRNA疫苗诱导了针对包括JN.1、KP.3.1.1和XEC在内的广泛SARS-CoV-2 Omicron亚变种的强健抗病毒体液免疫。 | Uriu, K. | N/A | Robust antiviral humoral immunity induced by JN.1 monovalent mRNA vaccines against a broad range of SARS-CoV-2 Omicron subvariants including JN.1, KP.3.1.1 and XEC | |
| 结合CRISPR激活和干扰能力，利用dCas9和G-四链体结构 | Kabir, M. L. | N/A | Combining the CRISPR Activation and Interference Capabilities Using dCas9 and G-Quadruplex Structures | |
| 一种综合方法：研究蜱虫幼虫和若虫叮咬小鼠以探讨莱姆病传播与感染 | Scholl, A. | N/A | A Comprehensive Method on Black-legged Tick Larvae and Nymph Feeding on Mice to Study Lyme Disease Transmission and Acquisition | |
| 组蛋白修饰和转座元件在基因重复后剂量表观遗传调控中的作用 | Wolfe, T. D. | N/A | The role of histone modifications and transposable elements in the epigenetic regulation of dosage after gene duplication | |
| 复杂性状尾部的多基因结构显著偏离 | Souaiaia, T. | N/A | Striking Departures from Polygenic Architecture in the Tails of Complex Traits | |
| 环节动物管虫Galeolaria caespitosa的分阶段染色体水平基因组 | Van Dorssen, M. | N/A | A phased chromosome-level genome of the annelid tubeworm Galeolaria caespitosa | |
| 大肠杆菌天冬氨酸转氨甲酰酶的核苷酸依赖性变构调节机制 | Miller, R. C. | N/A | Mechanism of Nucleotide-Dependent Allosteric Regulation in Escherichia coli Aspartate Transcarbamoylase | |
| 卵巢癌失调的长非编码RNA中的G四链体结构及其与人血清白蛋白的结合相互作用 | Singh, D. | N/A | G-quadruplex Structures in Dysregulated Long Non-Coding RNA of Ovarian Cancer and their Binding Interactions with Human Serum Albumin | |
| 经过工程改造的线粒体A-to-G编辑器，具有增强的效率和靶向范围 | Chen, L. | N/A | Engineered mitochondrial A-to-G editors with enhanced efficiency and targeting scope | |
| 通过可植入无线OLEDs进行深部器官癌症的光动力疗法 | Itazaki, Y. | N/A | Photodynamic Therapy for Deep Organ Cancer by Implantable Wireless OLEDs | |
| 计算机辅助多层次优化假单胞菌中丙二酰辅酶A的可用性 | Batianis, C. | N/A | Computer assisted multi-level optimization of malonyl-CoA availability in Pseudomonas putida | |
| 发现组织和维持神经回路的可塑性规则 | Bell, D. | N/A | Discovering plasticity rules that organize and maintain neural circuits | |
| 肽聚合物二级结构在抗菌效力和抗生素增效中的作用 | Barman, S. | N/A | The role of secondary structures of peptide polymers on antimicrobial efficacy and antibiotic potentiation | |
| 古菌细胞周期的转录图谱在真核生物中广泛保守 | Gomez-Raya-Vilanova, M. V. | N/A | Transcriptional landscape of the archaeal cell cycle is broadly conserved in eukaryotes | |
| 化学恒化培养法可降低粪便真核病毒载量，并延缓病毒组移植后的腹泻发生。 | Offersen, S. M. | N/A | Chemostat culturing reduces fecal eukaryotic virus load and delays diarrhea after virome transplantation | |
| 在基于肠道的阿尔茨海默病果蝇模型中产生的Abeta聚集物的多样性 | Elovsson, G. | N/A | Diversity of Abeta aggregates produced in a gut-based Drosophila model of Alzheimer's disease | |
| 心脏p38抑制突显磷酸蛋白质组在心力衰竭进展中的作用 | Sedighi, S. | N/A | Inhibition of Cardiac p38 Highlights the Role of the Phosphoproteome in Heart Failure Progression | |
| SARS-CoV-2 Spike蛋白跨膜区的序列和结构完整性对于病毒进入宿主细胞至关重要。 | Ortiz-Mateu, J. | N/A | The sequence and structural integrity of the SARS-CoV-2 Spike protein transmembrane domain is crucial for viral entry | |
| 一种可诱导Cre和Flp组合重组的顺序事件响应型荧光报告系统 | Pessina, G. | N/A | A sequential event-responsive fluorescent reporter for inducible Cre and Flp combinatorial recombination | |
| 人类eIF2A在翻译起始和uORF介导的翻译调控中起着微小的作用。 | Teleman, A. A. | N/A | Human eIF2A has a minimal role in translation initiation and in uORF-mediated translational control | |
| 冷诱导的GOT1在棕色脂肪组织中激活苹果酸-天冬氨酸穿梭，以支持对脂肪酸的燃料偏好。 | Park, C.-H. | N/A | Cold-inducible GOT1 activates the malate-aspartate shuttle in brown adipose tissue to support fuel preference for fatty acids | |
| 对多样性杂交小鼠研究中的寿命进行分析，发现了多个与长寿相关的基因座 | Mullis, M. N. | N/A | Analysis of lifespan across Diversity Outbred mouse studies identifies multiple longevity-associated loci | |
| PHRF1的PHD指对组蛋白H3 N端识别对于适当的DNA损伤反应是必需的。 | Jain, K. | N/A | Histone H3 N-terminal recognition by the PHD finger of PHRF1 is required for proper DNA damage response | |
| SPO11二聚化调控减数分裂DNA双链断裂的形成 | Oger, C. A. | N/A | SPO11 dimerization controls meiotic DNA double-strand break formation | |
| 利用密度和能量引导评估，自动识别冷冻电镜数据中的小分子 | Muenks, A. | N/A | Automated identification of small molecules in cryo-electron microscopy data with density- and energy-guided evaluation | |
| 一个评估肉类替代品的建议框架 | Semper, C. | N/A | A proposed framework for evaluating meat alternatives | |
| 评估当前长读长宏基因组菌株解析工具的性能 | Afolayan, A. O. | N/A | Assessing the performance of current strain resolution tools on long-read metagenomes | |
| 等离子体激活水对百脉根丛枝菌根共生关系的调节作用 | Cortese, E. | N/A | Modulatory effect of plasma-activated water on arbuscular mycorrhizal symbiosis in Lotus japonicus | |
| 渔猫化学通讯的功能性见解：半水生栖息地适应的策略机制 | Das, S. | N/A | Functional insights on chemical communication of fishing cats: a strategic mechanism for adaptation in semi-aquatic habitat | |
| 多模态测量的整合揭示了结核病药物作用的关键机制 | Johnson, W. C. | N/A | Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug action | |
| 移植地点对在家与在医院接受造血干细胞移植患者的肠道微生物群和抗性组的影响 | Andermann, T. M. | N/A | The impact of transplant location on the gut microbiome and resistome in patients undergoing hematopoietic stem cell transplantation at home versus in the hospital | |
| RNA聚合酶II亚基的过表达会引发基因组不稳定性并扰乱转录调控。 | Sadurni, M. M. | N/A | RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcription | |
| 基于多组学的2D和3D人类iPSC-心肌细胞胰岛素抵抗模型评估显示，其代谢和收缩功能障碍再现了糖尿病心肌病的特征。 | Carter, R. D. | N/A | Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy. | |
| 浮游植物光合生理学揭示了特定深度的浮游动物摄食情况 | Graff, J. R. | N/A | Phytoplankton Photophysiology Reveals Depth Specific Zooplankton Grazing | |
| 本地和入侵植物群落中蜱虫暴露风险的机制途径 | Hiatt, D. | N/A | Mechanistic pathways of tick exposure risk in native and invaded plant communities | |
| 负韧性趋势导致地中海橡树物种更频繁的极端干旱 | Vazquez, I. B. | N/A | Negative resilience trends to more frequent extreme droughts in Mediterranean oak species | |
| # BioRxiv 2024-11-19 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 将昆虫社会的基本概念适应于生物本体论的需求。 | Silva, T. S. R. | N/A | Adapting fundamental concepts from insect societies to the demands of bio-ontologies. | |
| 通过咽部神经元对黑腹果蝇的盐味行为进行活动和状态依赖性调节 | Kaushik, S. | N/A | Activity and state-dependent modulation of salt taste behavior via pharyngeal neurons in Drosophila melanogaster | |
| 语义控制的晚熟促进了概念的发展 | Jackson, R. L. | N/A | Late maturation of semantic control promotes conceptual development | |
| 气味表征表明，在整个嗅觉系统中存在非线性处理过程。 | Olivares, J. | N/A | Odorant representations indicate nonlinear processing across the olfactory system | |
| 有效的保护决策需要针对特定目的设计的模型：安大略省“火环”地区北美驯鹿的案例研究 | Dyson, M. E. | N/A | Effective conservation decisions require models designed for purpose: a case study for boreal caribou in Ontario's Ring of Fire | |
| BATCH-SCAMPP：批量缩放的系统发育放置大型树 | Wedell, E. | N/A | BATCH-SCAMPP: Batch Scaled Phylogenetic Placement Large Trees | |
| 剖析咖啡因在裂殖酵母中的细胞周期调控、DNA损伤敏感性和寿命效应 | Alao, J.-P. | N/A | Dissecting the cell cycle regulation, DNA damage sensitivity and lifespan effects of caffeine in fission yeast | |
| 阿尔茨海默病和重度抑郁症中的比较基因调控网络分析揭示了共享的核心调控回路 | Puype, H. | N/A | Comparative gene regulatory network analysis in Alzheimer's disease and major depressive disorder identifies shared core regulatory circuits | |
| 帕金森病的分类及从皮脂挥发物组中描绘进展标志物 | Walton-Doyle, C. | N/A | Classification of Parkinson's Disease and Delineating Progression Markers from the Sebum Volatilome | |
| 经验生态网络推断的不一致性受统计方法和输入数据维度的考虑所支配。 | Kusch, E. | N/A | Inconsistencies of empirical ecological network inference are governed by considerations of statistical approaches and dimensions of input data | |
| 一种适用于慢性神经像素探针的可适应、可重复使用且轻便的植入物 | Bimbard, C. | N/A | An adaptable, reusable, and light implant for chronic Neuropixels probes | |
| 解码视觉空间注意力控制 | Meyyappan, S. | N/A | Decoding Visual Spatial Attention Control | |
| 评估不同突变发现方法之间的不一致体细胞变异，以最小化药物耐药性发现的假阴性结果 | Lin, H.-F. | N/A | Evaluating discordant somatic calls across mutation discovery approaches to minimize false negative drug-resistant findings | |
| 小鼠听觉皮层中的多模态失配反应 | Solyga, M. | N/A | Multimodal mismatch responses in mouse auditory cortex | |
| 使用扰动-观察对进行自动模型优化 | Park, K. H. | N/A | Automated Model Refinement Using Perturbation-Observation Pairs | |
| 一个热力学框架，用于分析非平衡自组装和分支肌动蛋白网络中的力形态权衡 | Rennert, E. | N/A | A thermodynamic framework for nonequilibrium self-assembly and force morphology tradeoffs in branched actin networks | |
| 活体成像揭示了哺乳动物原肠胚形成过程中协调的细胞迁移和心脏命运决定。 | Abukar, S. | N/A | Live-imaging reveals Coordinated Cell Migration and Cardiac Fate Determination during Mammalian Gastrulation. | |
| 单细胞多组学揭示了细胞周期中mRNA代谢和染色质可及性的振荡动力学 | Nariya, M. K. | N/A | Single-cell multiomics reveals the oscillatory dynamics of mRNA metabolism and chromatin accessibility during the cell cycle | |
| 重复的行为进化与洞巢鸣禽基因表达的定向趋同有关 | Lipshutz, S. E. | N/A | Repeated behavioral evolution is associated with targeted convergence of gene expression in cavity-nesting songbirds | |
| 双分病毒内体膜靶向中VP3-PI3P相互作用的作用 | Zanetti, F. A. | N/A | On the Role of VP3-PI3P Interaction in Birnavirus Endosomal Membrane Targeting | |
| 抗-B7H3 CAR-T结构的功能亲和力预测了触发效应功能的抗原密度阈值 | Barisa, M. | N/A | Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function | |
| NAD+激活肾脏代谢，并在Alport综合征模型中保护免受慢性肾脏疾病的侵害。 | Jones, B. A. | N/A | NAD+ activates renal metabolism and protects from chronic kidney disease in a model of Alport syndrome | |
| 使用QCM-D解码新兴肌动肌球蛋白交叉对话的机械化学影响 | Kerivan, E. M. | N/A | Deciphering Mechanochemical Influences of Emergent Actomyosin Crosstalk using QCM-D | |
| 通过综合分析基因表达数据识别胶质母细胞瘤的潜在治疗靶点和生物标志物 | Bautista, A. | N/A | Identification of Potential Therapeutic Targets and Biomarkers for Glioblastomas Through Integrative Analysis of Gene Expression Data | |
| 通过函数分配的掩码超串实现高效的k-Mer集合操作 | Sladky, O. | N/A | Towards Efficient k-Mer Set Operations via Function-Assigned Masked Superstrings | |
| 嗜水气单胞菌CobQ是一种新型的不依赖NAD+和Zn2+的蛋白质赖氨酸去乙酰化酶。 | Wang, Y. | N/A | Aeromonas hydrophila CobQ is a new type of NAD+- and Zn2+-independent protein lysine deacetylase | |
| 一段基因组复制跨越多个P450基因，有助于登革热蚊子埃及伊蚊的杀虫剂抗性 | Bacot, T. | N/A | A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti | |
| 体感诱发电位在啮齿动物中引起广泛的弥散度和峰度变化，这些变化与神经活动相关。 | Hertanu, A. | N/A | Somatosensory-evoked response induces extensive diffusivity and kurtosis changes associated with neural activity in rodents | |
| 围产期结构丘脑皮质连接的发展 | Oldham, S. | N/A | Perinatal development of structural thalamocortical connectivity | |
| 持续的疫苗暴露能更快、更一致且更广泛地激发对多价流感疫苗的体液免疫反应。 | Saouaf, O. M. | N/A | Sustained vaccine exposure elicits more rapid, consistent, and broad humoral immune responses to multivalent influenza vaccines | |
| 大脑中双向网络核心与感知觉意识和认知的关联 | Taguchi, T. | N/A | Association of bidirectional network cores in the brain with perceptual awareness and cognition | |
| 96孔聚丙烯酰胺凝胶用于电泳和Western印迹 | Birtwistle, M. R. | N/A | A 96-Well Polyacrylamide Gel for Electrophoresis and Western Blotting | |
| 多结构域信号蛋白的深度突变扫描揭示了调控机制和致病性 | Jiang, Z. | N/A | Deep mutational scanning of a multi-domain signaling protein reveals mechanisms of regulation and pathogenicity | |
| 海马体在类别抽象过程中支持向新状态的插值 | Schaefer, T. A. | N/A | The hippocampus supports interpolation into new states during category abstraction | |
| 一种用于在低功耗神经形态硬件上监测癫痫发作的事件驱动神经网络 | Bartels, J. | N/A | An event-driven neural network for monitoring of epileptic seizures on low-power neuromorphic hardware | |
| 环二腺苷酸驱动沙眼衣原体发育周期的进展 | Lee, J. | N/A | Cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis | |
| 组成性激活的受体ADGRA3信号传导诱导脂肪组织产热 | Zhao, Z. | N/A | Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis | |
| 评估漂变和选择在沿海拔梯度特征丧失中的作用 | Buysse, S. F. | N/A | Evaluating the Roles of Drift and Selection in Trait Loss along an Elevational Gradient | |
| 特定的突触前功能需要不同的果蝇Cav2剪接异构体 | Bell, C. | N/A | Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms | |
| 通过抑制NLRP3炎症小体，被caspase-11/4切割的VgrG2b片段促进了铜绿假单胞菌的感染。 | Qian, Y. | N/A | A VgrG2b fragment cleaved by caspase-11/4 promotes Pseudomonas aeruginosa infection through suppressing the NLRP3 inflammasome | |
| 基于模型的祖先比例更快速估算 | Santander, C. | N/A | Faster model-based estimation of ancestry proportions | |
| 一种全面的蛋白质组结构系统方法揭示了所有人疱疹病毒蛋白质家族的见解 | Soh, T. K. | N/A | A proteome-wide structural systems approach reveals insights into protein families of all human herpesviruses | |
| 桡足类化学信号对两种拟菱形藻属物种胞内和胞外毒素的影响 | Pourdanandeh, M. | N/A | Effects of copepod chemical cues on intra- and extracellular toxins in two species of Dinophysis | |
| FuncFetch：一种由大型语言模型辅助的工作流程，能够从已发表的手稿中挖掘出数千种酶-底物相互作用 | Smith, N. | N/A | FuncFetch: An LLM-assisted workflow enables mining thousands of enzyme-substrate interactions from published manuscripts | |
| 多物种全基因组CRISPR筛选鉴定出冷诱导细胞死亡的保守抑制因子 | Lam, B. | N/A | Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death | |
| 年龄相关的听觉脑干髓鞘缺陷会导致鸡尾酒会效应的缺陷。 | Poleg, S. | N/A | Age-related myelin deficits in the auditory brain stem contribute to cocktail party-deficits | |
| 高度可扩展的物理交联水凝胶用于高速3D生物打印 | Song, Y. E. | N/A | Highly extensible physically crosslinked hydrogels for high-speed 3D bioprinting | |
| 使用机器学习预测单克隆抗体的纯化工艺适用性 | Maier, A. J. | N/A | Predicting purification process fit of monoclonal antibodies using machine learning | |
| 可移动元件通过细胞类型特异性的表观基因组关联影响人类调控景观 | Hyacinthe, J. | N/A | Transposable elements impact the human regulatory landscape through cell type specific epigenomic associations | |
| 通过整合进化尺度和基于物理的建模来预测金属结合蛋白及其结构 | Dai, X. | N/A | Predicting metal-binding proteins and structures through integration of evolutionary-scale and physics-based modeling | |
| 蛋白质工程竞赛结果：蛋白质建模与设计的开放科学基准 | Armer, C. | N/A | Results of the Protein Engineering Tournament: An Open Science Benchmark for Protein Modeling and Design | |
| 内侧隔核和Broca斜带中的神经元异质性：类别与连续体 | Kuhn, F. | N/A | Neuronal heterogeneity in the medial septum and diagonal band of Broca: classes and continua | |
| 细胞-细胞外基质（ECM）粘附的局部减弱通过改变细胞形状、肌动蛋白-肌球蛋白组织和E-钙粘蛋白水平，触发了基底组织的折叠。 | Valencia-Exposito, A. | N/A | Local weakening of cell-ECM adhesion triggers basal tissue folding via changes in cell shape, actomyosin organization and E-cad levels | |
| 阿尔茨海默病突变型γ-分泌酶复合物阻碍了β-淀粉样肽的生成。 | Arafi, P. | N/A | Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production | |
| 根据实验室观察，成熟的大黄蜂蛹在夜间仍会继续鸣叫。 | FUJIOKA, H. | N/A | Mature larvae continue calling at night in Vespa mandarinia from laboratory observations | |
| 关于前向采样方案密度的近似严格下界 | Kille, B. | N/A | A near-tight lower bound on the density of forward sampling schemes | |
| 遗传性铜缺乏和儿童神经退行性变模型中的适应性蛋白质合成 | Lane, A. R. | N/A | Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration | |
| 利用公开的数据非依赖采集数据集对人类组织中基线蛋白质表达的整合视图 | Prakash, A. | N/A | Integrated View of Baseline Protein Expression in Human Tissues using public Data Independent Acquisition datasets | |
| 不同的持续时间和饮食依赖性脂质谱及GCK-MODY中的肾并发症 | Huang, Y. | N/A | Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY | |
| DiffPaSS - 使用软分数进行高性能可微蛋白质序列配对 | Lupo, U. | N/A | DiffPaSS - High-performance differentiable pairing of protein sequences using soft scores | |
| 多尺度光场显微镜平台，用于多功能动态体积生物成像 | Bai, Y. | N/A | Multiscale Light Field Microscopy Platform for Multi-purpose Dynamic Volumetric Bioimaging | |
| CalTrig：一种基于图形用户界面的机器学习方法，用于解码自由活动啮齿动物中的神经元钙瞬变 | Lange, M. A. | N/A | CalTrig: A GUI-based Machine Learning Approach for Decoding Neuronal Calcium Transients in Freely Moving Rodents | |
| 基于系统发育的模拟表明，在真核生物起源时期，未采样的谱系对基因流推断的影响较小。 | Bernabeu, M. | N/A | Phylogeny-aware simulations suggest a low impact of unsampled lineages in the inference of gene flow during eukaryogenesis | |
| 用于高效遗传种群鉴定的特诺河大西洋鲑（Salmo salar）种群复合体的单核苷酸多态性基因分型面板 | Johansson, H. | N/A | A single nucleotide polymorphism genotyping panel for efficient genetic stock identification of the Teno river Atlantic salmon (Salmo salar) population complex | |
| 解读未开发古菌域中RiPPs的化学语言 | Song, Z.-m. | N/A | Decoding the chemical language of RiPPs from the untapped Archaea domain | |
| Vispro 提升了 Visium 空间转录组学的成像分析 | Ma, H. | N/A | Vispro improves imaging analysis for Visium spatial transcriptomics | |
| 深度学习助力Pharos平台发现激酶药物靶点 | Halasz, A. M. | N/A | Deep Learning enabled discovery of kinase drug targets in Pharos | |
| 利用-配对目标的RF扩散改进蛋白质结合剂设计 | Sappington, I. | N/A | Improved protein binder design using -pairing targeted RFdiffusion | |
| 多站点研究中基于扩散MRI的结构连接组的协调 | Shen, R. S. | N/A | Harmonization of Diffusion MRI-based Structural Connectomes for Multi-site Studies | |
| 赋予抗真菌药物抗性的RNAi表观突变是可遗传的。 | Perez-Arques, C. | N/A | RNAi epimutations conferring antifungal drug resistance are inheritable | |
| 光照在弱电鱼的活动感知和控制中起着中介作用，能够调节其行为模式。 | Yeh, H. | N/A | Illumination mediates a switch in both active sensing and control in weakly electric fish | |
| 全球范围内对预测模型进行基准测试，揭示长期中风结果的机制多样性 | Matsulevits, A. | N/A | A global effort to benchmark predictive models and reveal mechanistic diversity in long-term stroke outcomes | |
| SpotMAX：一种用于多维自动斑点检测和定量的通用框架 | Padovani, F. | N/A | SpotMAX: a generalist framework for multi-dimensional automatic spot detection and quantification | |
| II型-B CRISPR-Cas9增强特异性的机制 | Hibshman, G. N. | N/A | Mechanism of type II-B CRISPR-Cas9 enhanced specificity | |
| 在人细胞培养中5-氟尿嘧啶处理下RNA修饰的时间定位 | Berg, M. | N/A | Temporal placement of RNA modifications under 5-fluorouracil treatment in human cell culture | |
| 一种跨越动物和环境的普遍海马体记忆编码 | Wirtshafter, H. S. | N/A | A universal hippocampal memory code across animals and environments | |
| 跨动物和环境的海马体通用记忆编码 | Wirtshafter, H. S. | N/A | A universal hippocampal memory code across animals and environments | |
| 使用多重竞争性等位基因特异性PCR（mxKASP）基因分型确定合子性 | de Visser, M. C. | N/A | Determining zygosity with multiplex Kompetitive Allele-Specific PCR (mxKASP) genotyping | |
| 保守的基因内容和独特的系统发育历史特征了Triturus平衡致死系统背后的“bloopergene” | de Visser, M. C. | N/A | Conserved gene content and unique phylogenetic history characterize the 'bloopergene' underlying Triturus' balanced lethal system | |
| NewtCap：一种高效的目标捕获方法，用于提升蝾螈科（真蝾螈和新蝾螈）的基因组研究 | de Visser, M. C. | N/A | NewtCap: an efficient target capture approach to boost genomic studies in Salamandridae (True Salamanders and Newts) | |
| 普通狨猴的拉绳行为 | Bertrand, M. | N/A | String-pulling by the common marmoset | |
| PAV-spotter：利用信号互相关识别目标捕获数据中的存在/缺失变异 | de Visser, M. C. | N/A | PAV-spotter: using signal cross-correlations to identify Presence/Absence Variation in target capture data | |
| 保守的转录因子通过抑制作用协调突触基因的表达 | Kentro, J. A. | N/A | Conserved transcription factors coordinate synaptic gene expression through repression | |
| 微生物转录对宿主饮食的反应维持了美洲大蠊肠道微生物群的稳态 | DePoy, A. N. | N/A | Microbial transcriptional responses to host diet maintain gut microbiome homeostasis in the American cockroach | |
| mcRigor：一种用于增强单细胞数据分析中metacell划分严谨性的统计方法 | Liu, P. | N/A | mcRigor: a statistical method to enhance the rigor of metacell partitioning in single-cell data analysis | |
| 稀有物种并未过度贡献于亚高山植物群落的系统发育多样性 | Veldhuisen, L. N. | N/A | Rare species do not disproportionately contribute to phylogenetic diversity in a subalpine plant community | |
| 秋水仙碱抑制小鼠平滑肌细胞表型转换及主动脉夹层 | Jiang, H. | N/A | Colchicine Inhibits Smooth Muscle Cell Phenotypic Switch and Aortic Dissection in Mice | |
| 一种关于单细胞习惯化的受体失活模型，适用于蓝钟虫（Stentor coeruleus） | Rajan, D. H. | N/A | A receptor-inactivation model for single-celled habituation in Stentor coeruleus | |
| 全息层析显微镜揭示了在血管内皮化过程中，无需标记的血管内皮细胞定量动态变化。 | Leineweber, W. D. | N/A | Holotomographic microscopy reveals label-free quantitative dynamics of endothelial cells during endothelialization | |
| 调节注意力网络中与学习相关的可塑性 | Conto, F. | N/A | Modulation of learning-dependent plasticity in the attention network | |
| 基因重复后表达变异性的增加有助于基因的保留 | Cai, H. | N/A | Expression variability following gene duplication facilitates gene retention | |
| ROSIE：从组织病理学图像中生成多重免疫荧光染色的人工智能技术 | Wu, E. | N/A | ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images | |
| 有丝分裂CIP2A-TOPBP1轴促进有丝分裂途径在MiDAS和MMEJ之间的选择。 | Martin, P. R. | N/A | The mitotic CIP2A-TOPBP1 axis facilitates mitotic pathway choice between MiDAS and MMEJ | |
| 小窝蛋白-1和AQP4作为遗传性脑淀粉样血管病中纤维蛋白原驱动脑血管病理的介质 | Singh, V. | N/A | Caveolin-1 and Aquaporin-4 as Mediators of Fibrinogen-Driven Cerebrovascular Pathology in Hereditary Cerebral Amyloid Angiopathy | |
| 表观遗传调节NLRP6炎症小体传感器作为一种治疗手段，以减少HIV/SIV感染中由坏死性凋亡驱动的胃肠黏膜功能障碍 | Premadasa, L. S. | N/A | Epigenetic modulation of NLRP6 inflammasome sensor as a therapeutic modality to reduce necroptosis-driven gastrointestinal mucosal dysfunction in HIV/SIV infection | |
| 区分果蝇中轻度、重度及非典型过氧化物酶体生成障碍的PEX基因变异严重程度 | Gomez, V. A. | N/A | Distinguishing PEX gene variant severity for mild, severe, and atypical peroxisome biogenesis disorders in Drosophila | |
| 无序玻璃纳米线基底通过光学衍射断层成像揭示了类似体内的星形胶质细胞形态 | Anantha, P. | N/A | Disordered glass nanowire substrates produce in vivo-like astrocyte morphology revealed by optical diffraction tomography | |
| 一种伴有婴儿肠结肠炎的自发性炎症的动物模型 | Wang, Y. | N/A | An animal model for autoinflammation with infantile enterocolitis | |
| 一种伴有婴儿肠结肠炎的自发性炎症动物模型 | Wang, Y. | N/A | An animal model for autoinflammation with infantile enterocolitis | |
| 通过微活检皮肤样本在不同温度下的mRNA管家基因稳定性分析，推进远程和低资源医疗服务的提供 | Nataren, N. | N/A | Advancing Remote and Low-Resource Healthcare Delivery with Microbiopsy Skin Sample mRNA Housekeeping Gene Stability Analysis Across Various Temperatures | |
| 酶约束的梅毒螺旋体代谢模型鉴定出甘油-3-磷酸脱氢酶作为替代电子受体 | Shahreen, N. | N/A | Enzyme-constrained Metabolic Model of Treponema pallidum Identified Glycerol-3-phosphate Dehydrogenase as an Alternate Electron Sink | |
| 基质硬度决定人肺成纤维细胞中独特的阿霉素诱导的衰老相关分泌表型和转录组特征 | Du, H. | N/A | Substrate Stiffness Dictates Unique Doxorubicin-induced Senescence-associated Secretory Phenotypes and Transcriptomic Signatures in Human Pulmonary Fibroblasts | |
| 磷脂酰乙醇胺是一种吞噬性配体，参与微生物胞外囊泡的结合和清除。 | Kavianpour, A. | N/A | Phosphatidylethanolamine is a phagocytic ligand implicated in the binding and removal of microbial extracellular vesicles | |
| 补偿传感器运动延迟需要一个记忆缓冲区、一个状态观测器和一个预测器。 | Maris, E. | N/A | Compensating for a sensorimotor delay requires a memory buffer, a state observer, and a predictor | |
| 氯离子稳态的动态变化在奖励学习过程中协调中脑抑制性网络活动 | Woo, J. | N/A | Dynamic Changes in Chloride Homeostasis Coordinate Midbrain Inhibitory Network Activity during Reward Learning | |
| 使用多电极阵列对人类诱导多能干细胞衍生的感觉神经元进行分析，以用于镇痛药物筛选 | Kuete, C. F. | N/A | Profiling Human iPSC-Derived Sensory Neurons for Analgesic Drug Screening Using a Multi-Electrode Array | |
| 近红外光疗法治疗神经退行性疾病的效果评估：穿透深度有限，可能影响疗效 | Tittelmeier, J. | N/A | Evaluation of near-infrared light therapy for the treatment of neurodegenerative diseases: Limited penetration depth into the brain likely hinders efficacy | |
| 在刺激暴露期间，婴儿的大脑会迅速适应视觉统计规律。 | Capparini, C. | N/A | The infant brain rapidly entrains to visual statistical regularities during stimulus exposure | |
| 前庭信号到初级视觉皮层（V1）的半球间和半球内来源 | Bouvier, G. | N/A | Inter- and Intrahemispheric Sources of Vestibular Signals to V1 | |
| 关于吸引力序列依赖背后的决策过程的神经证据 | Shan, J. | N/A | Neural evidence for decision-making underlying attractive serial dependence | |
| 在呼气末二氧化碳质量较低时，使用屏气BOLD fMRI进行脑血管反应性振幅和延迟的定量映射 | Clements, R. G. | N/A | Quantitative mapping of cerebrovascular reactivity amplitude and delay with breath-hold BOLD fMRI when end-tidal CO2 quality is low | |
| 优化肌萎缩侧索硬化症（ALS）患者脑室内人神经干细胞移植的非临床方案中的挑战与前景 | Lombardi, I. | N/A | Challenges and promises in optimising a non-clinical protocol of intracerebroventricular human neural stem cell transplantation in ALS | |
| 通过药理学和遗传学方法揭示阿尔茨海默病中依赖与不依赖小胶质细胞的脑脂质代谢调控 | Xu, Z. | N/A | Microglia-Dependent and Independent Modulation of Brain Lipid Metabolism in Alzheimer's Disease Revealed by Pharmacological and Genetic Microglial Depletion | |
| 行为风险模型解释了在虚拟高度行走时的运动和平衡变化 | Seddighi, N. | N/A | Behavioral risk models explain locomotor and balance changes when walking at virtual heights | |
| 绘制DUSP6在ADHD iPSC衍生的多巴胺能神经元模型中的影响 | Namipashaki, A. | N/A | Mapping the impact of DUSP6 in an ADHD iPSC derived-dopaminergic neuronal model | |
| 治疗朊病毒病的治疗窗口由朊蛋白的定时消耗定义 | Bradford, B. M. | N/A | Therapeutic window for treatment of prion disease defined by timed depletion of Prion protein | |
| 靶向激活小胶质细胞PPARδ可重编程免疫代谢并增强饮食诱导肥胖中的胰岛素敏感性。 | Jiao, H. | N/A | Targeted activation of microglial PPARdelta reprograms immunometabolism and enhances insulin sensitivity in diet-induced obesity. | |
| 顶叶经颅交流电刺激对时间预测的三角相位依赖性调制 | Burke, R. | N/A | Delta phase-dependent modulation of temporal predictions by parietal transcranial alternating current stimulation | |
| 基于连接组学的特征选择性皮质回路模型 | Buendia, V. | N/A | Connectome-based models of feature selectivity in a cortical circuit | |
| 沿着皮层层次对视觉区域进行多模态分层表征 | Pizzuti, A. | N/A | Multimodal laminar characterization of visual areas along the cortical hierarchy | |
| 在发作性偏头痛患者中，攻击想象期间疼痛网络的激活受到干扰 | Perdigao, A. | N/A | Disrupted activation of pain networks during attack imagery in patients with episodic migraine | |
| GABA和甘氨酸在轴突切断的运动神经元细胞体上的突触释放，促进了运动轴突的再生。 | Wood, R. L. | N/A | GABA and glycine synaptic release on axotomized motoneuron cell bodies promotes motor axon regeneration | |
| 在类似体内状态下树突突触整合模式 | Ceballos, C. C. | N/A | Dendritic synaptic integration modes under in vivo-like states | |
| 生成网络模型未能准确捕捉到长程连接性。 | Oldham, S. | N/A | Coming up short: generative network models fail to accurately capture long-range connectivity | |
| 拓扑异构酶3A（TOP3A）依赖的端粒延长替代机制（ALT） | KHANDAGALE, P. R. | N/A | Topoisomerase 3A (TOP3A) Dependent Alternative Lengthening of Telomeres (ALT) | |
| CD40交联诱导的ERK激活促进了自噬，从而增强了宫颈癌细胞的放射敏感性。 | Liu, B. | N/A | CD40 ligation-induced ERK activation promotes autophagy which leads to enhanced radiosensitivity in cervical carcinoma cells | |
| 抑制GEF-H1-RhoA信号通路在炎症中的作用：通过模拟RhoA67-78螺旋的钉合肽 | Gathmann, C. | N/A | Inhibition of GEF-H1-RhoA signaling in inflammation with a stapled peptide mimicry of the RhoA67-78 helix | |
| 血管壁细胞保护成年大脑免受出血，但在发育中的斑马鱼中并不控制血脑屏障。 | Baltaci, O. F. | N/A | Vascular mural cells protect the adult brain from haemorrhage but do not control the blood-brain barrier in developing zebrafish | |
| 动物社会网络分析中未测量变量的问题：基于边的多层次模型能否提供可靠的解决方案？ | Bonnell, T. | N/A | The problem of unmeasured variables in animal social network analysis: can edge-based multilevel models provide a reliable solution? | |
| 阿尔茨海默病中的小胶质细胞状态易受衰老和胆固醇失调的影响 | Li, B. | N/A | Microglia States are Susceptible to Senescence and Cholesterol Dysregulation in Alzheimer's Disease | |
| 优化的人类诱导多能干细胞衍生的肝细胞的开发，以改善体外代谢疾病建模和毒性研究中的肝脏功能 | Lukasiak, M. | N/A | Development of optimised human iPSC-derived hepatocytes with improved liver function for in vitro metabolic disease modelling and toxicity studies | |
| 体内人体子宫温度、pH值及子宫液成分分析 | Tarahomi, M. | N/A | In vivo human uterine temperature, pH, and uterine fluid composition analysis | |
| 在调整淋巴细胞后，帕金森病全血RNA分析中SNCA表达的降低 | Xu, K. | N/A | Decreased SNCA Expression in Whole-Blood RNA Analysis of Parkinson's Disease Adjusting for Lymphocytes | |
| 自闭症谱系障碍中的低代谢：来自脑部和血液转录组学的见解 | Balasubramanian, R. | N/A | Hypometabolism in Autism Spectrum Disorder: Insights from Brain and Blood Transcriptomics | |
| 对加纳北部黄热病暴发的昆虫学调查 | Osei, J. H. N. | N/A | Entomological investigations into yellow fever outbreak in northern Ghana | |
| 评估脑龄作为脑健康的特定标志 | Tan, T. W. K. | N/A | Evaluation of Brain Age as a Specific Marker of Brain Health | |
| 从生物技术角度对源于真菌的抗菌药物进行综合文献计量研究 | Da Silva, L. L. | N/A | A Comprehensive Bibliometric Investigation on Antimicrobials from Fungal Origins with a Biotechnological Perspective | |
| 埃塞俄比亚塔纳湖湖滨湿地综合湿地状况指数的开发与应用 | Wondim, Y. K. | N/A | Development and use of integrated wetland condition index for lacustrine fringe wetlands of Lake Tana, Ethiopia | |
| 在问题解决过程中，眼睛和手的协同发音揭示了层级组织的规划。 | Eluchans, M. | N/A | Eye and hand coarticulation during problem solving reveals hierarchically organized planning | |
| 在蛋白质组尺度上分析氨基酸替代揭示了癌症疾病中的新型蛋白质调控 | Zhao, P. | N/A | Profiling amino acid substitution on proteomic scale unveils novel protein regulation in cancer diseases | |
| 双时间尺度电机电路动力学是快速头部探索行为和高效运动的基础 | Li, P. | N/A | Dual-timescale motor circuit dynamics underlies fast head exploratory behavior and efficient locomotion | |
| ELAVL3调控D1和D2纹状体中型多棘神经元中编码突触信号蛋白的RNA剪接。 | Irmady, K. | N/A | ELAVL3 regulates splicing of RNAs encoding synaptic signaling proteins in D1 and D2 striatal medium spiny neurons. | |
| Pick病中tau聚集体的分子多态性 | Liu, J. | N/A | Molecular Polymorphism of tau aggregates in Pick's disease | |
| CATSPERε的胞外域在发育过程中对CatSper的组装以及精子获能过程中的活性调节至关重要。 | Hwang, J. Y. | N/A | Extracellular domains of CATSPERε are essential for CatSper assembly during development and activity modulation in sperm capacitation | |
| 学术交流中的骗局趋势 | Faulkes, Z. | N/A | Trends in hoaxes of academic communication | |
| 病原体威胁的接近程度塑造了宿主在感染前反应中的胞外囊泡产生 | Kolodziejska, K. | N/A | Pathogen threat proximity shapes host extracellular vesicle production in pre-infection response | |
| 静纤毛高度的变化可以解释外毛细胞束静息状态对钙的依赖性。 | Chatterjee, R. | N/A | Stereocilium height changes can account for the calcium dependence of the outer-hair-cell bundle's resting state | |
| 利用临床试验数据和深度辅助学习优化三阴性乳腺癌新辅助治疗反应预测 | Moon, C. I. | N/A | Optimizing Neoadjuvant Treatment Response Prediction for Triple-Negative Breast Cancer Using Clinical Trial Data and Deep Auxiliary Learning | |
| 姜黄素和胡椒碱通过模拟和人工智能方法预防和治疗乳腺癌的分析 | Sivakumar, A. | N/A | Analysis of Curcumin and Piperine for Breast Cancer Prevention and Treatment via Simulation and Artificial Intelligence Methods | |
| 一种合成钾通道通过细胞自适应技术减轻氧化应激 | Russo, A. | N/A | A synthetic potassium channel reduces oxidative stress 1 via cellular adaptronics | |
| 病理性α-突触核蛋白截断和突变对相分离的不同影响 | Ray, S. | N/A | Divergent effects of pathological α-synuclein truncations and mutations on phase separation | |
| 通过体外重建揭示的染色质复制偶联对称组蛋白再循环的最小蛋白质列表 | Nagae, F. | N/A | Minimal protein list for chromatin replication-coupled symmetric histone recycling revealed through in vitro reconstitution | |
| 具有全局抑制的决策集成伊辛模型 | Tapinova, O. | N/A | Integrated Ising Model with global inhibition for decision making | |
| PTK7靶向放射性核素治疗的临床前评估 | Lindland, K. | N/A | Preclinical Evaluation of PTK7-Targeted Radionuclide Therapy | |
| 线性-二次模型（以及LQ模型的来源）的一个简单新替代方案 | Bilinsky, L. | N/A | A simple new alternative to the linear-quadratic model (and where the LQ model comes from) | |
| 巴雷特食管和癌症的单细胞分析揭示了通过遗传易感性赋予风险的细胞类型 | Wenzel, M. C. | N/A | Single cell analysis of Barrett's esophagus and carcinoma reveals cell types conferring risk via genetic predisposition | |
| 自监督学习发现的3446张全切片图像中切除的间皮瘤组织形态学图谱 | Seyedshahi, F. | N/A | A histomorphological atlas of resected mesothelioma from 3446 whole-slide images discovered by self-supervised learning | |
| mGluR同源和异源二聚体的独特药理学特性 | McCullock, T. W. | N/A | Unique Pharmacology of mGluR homo- and heterodimers | |
| 对玉米驯化过程中根系表型演变的硅基分析——以特瓦坎新石器时代土壤为例 | Lopez-Valdivia, I. | N/A | In silico analysis of the evolution of root phenotypes during maize domestication in Neolithic soils of Tehuacan | |
| 创新性突变筛选鉴定出TRANSPARENT TESTA7在种子油/蛋白质分配中的作用 | Lecureuil, A. | N/A | Innovative mutant screening identifies TRANSPARENT TESTA7 as a player in seed oil/protein partitioning | |
| X射线计算机断层扫描技术的应用彻底改变了土壤病原体的检测方式。 | Pereira, E. C. | N/A | The use of X-ray Computed Tomography revolutionises soil pathogen detection | |
| 关于Farlowella colombiensis Retzer & Page 1997的分类地位及F. acus物种组（Loricariidae科：Loricariinae亚科）物种的评注。 | Melo-Ortiz, O. E. | N/A | The taxonomic status of Farlowella colombiensis Retzer & Page 1997 with comments on species of the F. acus species group (Loricariidae: Loricariinae). | |
| 情绪通过偏差学习奖励可能性来影响信心 | Mason, L. | N/A | Mood impacts confidence through biased learning of reward likelihood | |
| 健康成年和新生儿非裔美国人皮肤中IL1A/IRAK1轴及其下游促炎信号的激活 | Trubetskoy, D. | N/A | Activation of IL1A/IRAK1 axis and downstream proinflammatory signaling in healthy adult and neonatal African American skin | |
| 与干扰素相关的B细胞过度活跃在携带Sm/RNP抗体的系统性红斑狼疮患者中高度富集。 | Van Dooren, H. J. | N/A | IFN-associated B cell hyperactivity is highly enriched in SLE patients harboring Sm/RNP antibodies | |
| 囊性纤维化患者来源的铜绿假单胞菌菌株中噬菌体防御系统减少 | van den Berg, D. F. | N/A | Reduced prevalence of phage defense systems in Pseudomonas aeruginosa strains from Cystic Fibrosis Patients | |
| 模拟人类子宫pH值和液体成分的胚胎培养基中的人类囊胚形成 | Zagers, M. S. | N/A | Human blastocyst formation in an embryo culture medium mimicking human uterine pH and fluid composition | |
| 全球生物地理学与具叶绿体孢子蕨类的进化驱动力 | Mellado-Mansilla, D. | N/A | GLOBAL BIOGEOGRAPHY AND EVOLUTIONARY DRIVERS OF FERNS WITH CHLOROPHYLLOUS SPORES | |
| 使用简单二分类器在FlowCAM中进行碎屑识别 | Garcia-Oliva, O. | N/A | Detritus identification in FlowCAM using a simple binary classifier | |
| 互惠的主-沃尔巴克氏体相互作用塑造了单倍二倍体中细胞质不兼容性丧失后的感染持久性 | KAUAI, F. | N/A | Reciprocal host-Wolbachia interactions shape infection persistence upon loss of cytoplasmic incompatibility in haplodiploids | |
| 使用卷积神经网络检测种间正选择 | West, C. | N/A | Detecting interspecific positive selection using convolutional neural networks | |
| 鲸偶蹄目中上皮钠通道delta亚单位的进化路径表明其在钠感应中的作用 | Zahnow, F. | N/A | The evolutionary path of the epithelial sodium channel delta-subunit in Cetartiodactyla points to a role in sodium sensing | |
| 有害突变可以促进性染色体间重组抑制的进化。 | Jay, P. | N/A | Deleterious mutations can contribute to the evolution of recombination suppression between sex chromosomes | |
| 着丝粒附近的交叉会破坏减数分裂过程中同源染色体的正常分离。 | Sen, S. | N/A | Centromere-proximal crossovers disrupt proper homologous chromosome disjunction during meiosis | |
| 优化多样化碱基编辑器以进行单核苷酸变异的高通量研究 | Schwartz, C. I. | N/A | Towards optimizing diversifying base editors for high-throughput studies of single-nucleotide variants | |
| 时空T细胞追踪用于儿童癌症个性化TCR-T设计 | Sentis, I. | N/A | Spatio-temporal T cell tracking for personalized TCR-T designs in childhood cancer | |
| Id1促进功能丧失型Tet2小鼠的克隆性造血 | Singh, S. | N/A | Id1 Promotes Clonal Hematopoiesis in Mice with Tet2 Loss of Function | |
| 准备用于核型分析和荧光原位杂交（FISH）的高质量番红花属植物染色体铺片 | El-nagish, A. | N/A | Preparing high-quality chromosome spreads from Crocus species for karyotyping and FISH | |
| 可扩展的无细胞生产活性T7 RNA聚合酶 | Rezvani, R. N. | N/A | Scalable cell-free production of active T7 RNA polymerase | |
| 哺乳动物大脑发育和进化中的双重计算系统 | Imam, N. | N/A | Dual Computational Systems in the Development and Evolution of Mammalian Brains | |
| 人类和狨猴在基于形状的视觉面孔辨别行为中表现出相似的面孔识别特征。 | Jeon, Y.-N. | N/A | Humans and marmosets share similar face recognition signatures in shape-based visual face discrimination behavior | |
| 利用扩散MRI中的基于模拟推理进行不确定性映射和概率性纤维束追踪：与经典贝叶斯方法的比较 | Manzano-Patron, J. P. | N/A | Uncertainty mapping and probabilistic tractography using Simulation-Based Inference in diffusion MRI: A comparison with classical Bayes | |
| 面向多模态纵向分析：利用神经影像生物标志物、认知评估及人口统计数据预测认知衰退 | Ashish, R. M. | N/A | Towards Multimodal Longitudinal Analysis for Predicting Cognitive Decline Using Neuroimaging Biomarkers, Cognitive Assessments, and Demographic Data | |
| PIEZO2机械敏感性离子通道在脂肪感觉神经支配中起关键作用 | Wang, Y. | N/A | A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation | |
| 时间预期调节额叶与感觉脑区之间的耦合 | Nagy, P. | N/A | Temporal expectations modulate coupling between frontal and sensory brain areas | |
| 感觉丧失后关键期后的丘脑皮质连接的转录和生理适应 | Iyer, L. | N/A | Post-Critical Period Transcriptional and Physiological Adaptations of Thalamocortical Connections after Sensory Loss | |
| 通过浦肯野细胞特异性删除Scn1b建立的发育性和癫痫性脑病小鼠模型 | Guillen, F. I. | N/A | A novel mouse model for developmental and epileptic encephalopathy by Purkinje cell-specific deletion of Scn1b | |
| 脊椎动物的视觉起源于竞争的锥体电路。 | Fornetto, C. | N/A | Vertebrate vision is ancestrally based on competing cone circuits | |
| 由激励驱动的可卡因觅药习惯与纹状体星形胶质细胞中多巴胺转运体的下调有关。 | Fouyssac, M. | N/A | Compulsion derived from incentive cocaine-seeking habits is associated with a downregulation of the dopamine transporter in striatal astrocytes | |
| 敲低TTLL1可减轻Aβ诱导的人诱导多能干细胞衍生的皮层神经元中的TAU病理 | Al Kabbani, M. A. | N/A | Knockdown of TTLL1 reduces Aβ-induced TAU pathology in human iPSC-derived cortical neurons | |
| 用于编码和解码与眼球运动相关神经活动的“眼反应函数” | Gehmacher, Q. | N/A | The "Ocular Response Function" for encoding and decoding oculomotor related neural activity | |
| 第二/三层连接的同向性偏差：自发、视觉和光遗传驱动的第一视皮层动态的统一机制 | Rozsa, T. | N/A | Iso-orientation bias of layer 2/3 connections: the unifying mechanism of spontaneous, visually and optogenetically driven V1 dynamics | |
| 气味调节焦虑水平，但脑电图和心电图评估可能与主观报告存在差异 | Morozova, M. | N/A | Scents Modulate Anxiety Levels, but Electroencephalographic and Electrocardiographic Assessments Could Diverge from Subjective Reports | |
| 听觉注意对唤醒的全球性和选择性影响：来自瞳孔扩张的洞察 | Grandjean, A. | N/A | Global and selective effects of auditory attention on arousal: insights from pupil dilation | |
| 与骨关节炎相关的鞘脂类神经酰胺34:1在老鼠中引起炎症性疼痛 | Rickman, R. H. | N/A | The osteoarthritis associated sphingolipid sphingomyelin 34:1 causes inflammatory pain in mice | |
| 体内CRISPR筛选鉴定出影响多发性骨髓瘤中CAR T细胞功能的关键修饰因子 | Korell, F. | N/A | In vivo CRISPR screens identify key modifiers of CAR T cell function in myeloma | |
| 综合宏基因组学与血液生物标志物分析揭示了运动员和非运动员在有氧和无氧干预下的不同代谢反应 | Zielinska, K. | N/A | Integrative Metagenomic and Blood Biomarker Analysis Reveals Distinct Metabolic Responses to Aerobic and Anaerobic Interventions in Athletic and Non-Athletic Individuals | |
| 肠道微生物及其代谢产物介导阻塞性睡眠呼吸暂停诱发的动脉粥样硬化 | Xue, J. | N/A | Gut Microbiota and Derived Metabolites Mediate Obstructive Sleep Apnea Induced Atherosclerosis | |
| 基于结冷胶的营养培养基增加了土壤微生物培养群落的多样性 | Kulikova, D. | N/A | Gellan gum-based nutrient medium increases the diversity of cultivated groups of soil microorganisms | |
| 大规模半自动化病毒传播定量分析揭示了斑块形成的多相结构 | Howell, L. M. | N/A | Large scale semi-automated quantification of viral spread reveals multi-phasic structure of plaque formation | |
| YTHDF1和YTHDC1 m6A阅读器蛋白调控HTLV-1 tax和hbz的活性 | King, E. M. | N/A | YTHDF1 and YTHDC1 m6A reader proteins regulate HTLV-1 tax and hbz activity | |
| RNA结合蛋白LIN28A在神经元分化过程中介导染色质动态变化 | Piscitelli, S. | N/A | The RNA binding protein LIN28A mediates chromatin dynamics during neuronal differentiation | |
| 肥胖相关的MRAP2变异损害了多个MC4R介导的信号通路 | Wyatt, R. A. | N/A | Obesity-associated MRAP2 variants impair multiple MC4R-mediated signaling pathways | |
| 人类脊髓类器官揭示细胞插入作为次级神经胚形成的一种保守机制 | Blanco-Ameijeiras, J. | N/A | HUMAN SPINAL CORD ORGANOIDS REVEAL CELL INTERCALATION AS A CONSERVED MECHANISM FOR SECONDARY NEURULATION | |
| 白海沿岸寡毛纲动物Lumbricillus sp.作为环节动物发育研究的模型 | Matveicheva, E. P. | N/A | The White Sea littoral oligochaete Lumbricillus sp. as a model for annelid development studies | |
| 人类和小鼠造血干细胞的单细胞谱系偏向比较 | Shamie, I. | N/A | Comparative single-cell lineage bias in human and murine hematopoietic stem cells | |
| RNA编辑是未修饰人体细胞中的分子钟 | Ghareeb, A. E. | N/A | RNA editing is a molecular clock in unmodified human cells | |
| 纳米孔测序技术在检测多种DNA修饰方面的关键评估 | Kong, Y. | N/A | Critical assessment of nanopore sequencing for the detection of multiple forms of DNA modifications | |
| 空间解析活体CRISPR筛选测序通过Perturb-DBiT | Baysoy, A. | N/A | Spatially Resolved in vivo CRISPR Screen Sequencing via Perturb-DBiT | |
| 从RNA-蛋白质相互作用预测RNA稳定性的细胞类型特异性 | Saran, S. | N/A | Cell-type specific prediction of RNA stability from RNA-protein interactions | |
| 构建一个互惠底物处理木质纤维二糖的共生假单胞菌菌群 | Buryskova, B. | N/A | Building a syntrophic Pseudomonas putida consortium with reciprocal substrate processing of lignocellulosic disaccharides | |
| 开发一种针对自噬靶向降解的p62生物降解剂 | Thiel, Z. | N/A | Development of a p62 biodegrader for autophagy targeted degradation | |
| 前外侧系统中表达生长抑素神经元的解剖学特征 | Ma, W. | N/A | Anatomical characterisation of somatostatin-expressing neurons belonging to the anterolateral system | |
| 早期生命免疫激活塑造小胶质细胞反应并减少5xFAD小鼠的Aβ病理 | Yang, Y. | N/A | Early-Life Immune Activation Shapes Microglial Responses and Reduces Abeta Pathology in 5xFAD mice | |
| 2024年5月老年人血清中针对SARS-CoV-2 KP.3.1.1和XEC的中和抗体水平较低 | Fossum, E. | N/A | Low levels of neutralizing antibodies against SARS-CoV-2 KP.3.1.1 and XEC in serum from seniors in May 2024 | |
| CRAGE-RB-PI-seq技术能够在植物根系定殖过程中对根际细菌进行转录组分析。 | Honda, T. | N/A | CRAGE-RB-PI-seq enables transcriptional profiling of rhizobacteria during plant-root colonization | |
| 微生物群的宿主起源驱动小鼠的功能恢复和艰难梭菌清除 | Millard, S. A. | N/A | Host origin of microbiota drives functional recovery and Clostridioides difficile clearance in mice | |
| 与越南H5N1分离株相比，牛源H5N1在小鼠中表现出增强的脑炎趋向性。 | Goldin, K. | N/A | Enhanced encephalitic tropism of bovine H5N1 compared to the Vietnam H5N1 isolate in mice | |
| PTBP1通过HIF-1α信号被寨卡病毒感染上调，并劫持NS1蛋白以诱导NS1降解，从而抑制病毒复制。 | Rao, M. | N/A | PTBP1 is upregulated by Zika virus infection via HIF-1alpha signal and hijacks NS1 protein to induce NS1 degradation to restrain viral replication | |
| 一种无抗生素的抗菌组合：细菌素与肽聚糖水解酶的组合：体外和体内评估其功效 | Kranjec, C. | N/A | An antibiotic-free antimicrobial combination of bacteriocins and a peptidoglycan hydrolase: in vitro and in vivo assessment of its efficacy | |
| 一种高度保守的小RNA在百日咳博德特菌的毒力模式中下调多个基因，包括一个sigma54转录激活因子。 | Sim, M. | N/A | A highly conserved sRNA downregulates multiple genes, including a sigma54 transcriptional activator, in the virulence mode of Bordetella pertussis | |
| 小檗碱：一种兼具抗HIV和抗宫颈癌作用的化合物 | Naushad, W. | N/A | Berberine: A dual anti-HIV and anti- cervical cancer compound | |
| eDNA复制、聚合酶和扩增子大小影响跨栖息地丰富度的推断 | Anmarkrud, J. A. | N/A | eDNA replicates, polymerase and amplicon size impact inference of richness across habitats | |
| 卵巢生殖干细胞的去分化依赖于细胞突起 | Sutcliffe, C. | N/A | Ovarian germline stem cell dedifferentiation is cytoneme-dependent | |
| 内皮Rho激酶控制血管完整性和血管生成 | Lange, M. | N/A | Endothelial Rho kinase controls blood vessel integrity and angiogenesis | |
| 连续定向酶进化的海市蜃楼：以植物化细菌THI4酶为例的警示性研究 | Van Gelder, K. | N/A | Mirages in continuous directed enzyme evolution: A cautionary case study with plantized bacterial THI4 enzymes | |
| 用于病毒学研究的卡罗莱纳短尾蝠（Carollia perspicillata）细胞的病毒易感性和先天免疫能力 | Gonzalez, V. | N/A | Viral susceptibility and innate immune competency of Carollia perspicillata bat cells produced for virological studies | |
| SARM1激活通过两步液相到固相的相变促进轴突退化 | Zhang, W. | N/A | SARM1 Activation Promotes Axonal Degeneration Via a Two-Step Liquid-to-Solid Phase Transition | |
| # BioRxiv 2024-11-18 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 已撤回：成年小鼠齿状回苔藓细胞对颗粒细胞和CA3区的兴奋性影响：体外和体内研究。 | Bernstein, H. L. | N/A | WITHDRAWN: Excitatory effects of dentate gyrus mossy cells on granule cells and area CA3: an vitro and in vivo study in adult mice. | |
| 基于HHpred方法对SARS-CoV-2蛋白质进行重新注释，为更深入理解该病毒开启了新的机遇 | Brezellec, P. | N/A | Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus | |
| 在小鼠决策过程中，先验信息的全脑表征 | Findling, C. | N/A | Brain-wide representations of prior information in mouse decision-making | |
| 杜兴肌营养不良症（Duchenne Muscular Dystrophy）中成纤维细胞的包含导致疾病加重，MYOrganoids揭示了微肌营养不良蛋白治疗效力的局限性 | Palmieri, L. | N/A | Disease exacerbation by fibroblast inclusion in Duchenne Muscular Dystrophy MYOrganoids reveals limitations of microdystrophin therapeutic efficacy | |
| 从孵化场到远洋：气候变化与鲑鱼海洋生存的关联 | Kitada, S. | N/A | Hatcheries to high seas: climate change connections to salmon marine survival | |
| scELMo：来自语言模型的嵌入在单细胞数据分析中是优秀的学习者 | Liu, T. | N/A | scELMo: Embeddings from Language Models are Good Learners for Single-cell Data Analysis | |
| 可3D打印的非侵入性非人灵长类动物头部固定系统 | Shahbazi, E. | N/A | 3D-Printable Non-invasive Head Immobilization System for Non-Human Primates | |
| 撤回：人类胎盘中截短的NLRC5异构体：表达、由miR-218-5p调控及其在滋养层细胞中的功能 | Shan, Y. | N/A | WITHDRAWN: Truncated NLRC5 isoforms in human placenta: expression, regulation by miR-218-5p, and function in trophoblasts | |
| 记忆元认知成分由楔前叶与海马之间高伽马活动所支持的结构构成 | Pan, K. | N/A | Components of Mnemonic Metacognition Constitutionally Supported by High Gamma Activity Between the Precuneus and Hippocampus | |
| 两亲螺旋8的膜曲率关联驱动组成型GPCR内吞作用 | Herlo, R. | N/A | Membrane curvature association of amphipathic helix 8 drives constitutive GPCR endocytosis | |
| 超越皮层几何：罕见的长程连接塑造的大脑动力学 | Vohryzek, J. | N/A | Beyond cortical geometry: brain dynamics shaped by rare long-range connections | |
| 人CD29+/CD56+肌源性前体细胞展现出向腱细胞分化的潜力，并能促进肌腱的再生。 | Shao, X. | N/A | Human CD29+/CD56+ myogenic progenitors display tenogenic differentiation potential and facilitate tendon regeneration | |
| 肉食性动物的适应性景观揭示了头骨、附肢骨骼和轴向骨骼之间的功能权衡。 | Law, C. | N/A | The carnivoran adaptive landscape reveals functional trade-offs among the skull, appendicular, and axial skeleton | |
| 一种新型进食机制：太阳鸟通过舌内吸力饮用花蜜 | Cuban, D. | N/A | A novel feeding mechanism: Sunbirds drink nectar via intralingual suction | |
| 药物激活整合应激反应激酶抑制病理性线粒体碎片化 | Baron, K. R. | N/A | Pharmacologic Activation of Integrated Stress Response Kinases Inhibits Pathologic Mitochondrial Fragmentation | |
| 发现猴痘病毒H3中的硫酸乙酰肝素结合域作为抗痘病毒药物靶点：结合AI与MD模拟 | Zheng, B. | N/A | Discovery of a Heparan Sulfate Binding Domain in Monkeypox Virus H3 as an Anti-poxviral Drug Target Combining AI and MD Simulations | |
| BiRNA-BERT通过自适应分词实现了高效的RNA语言建模 | Tahmid, M. T. | N/A | BiRNA-BERT Allows Efficient RNA Language Modeling with Adaptive Tokenization | |
| 基于接触的胸苷酸转移促进集体肿瘤生长 | Siddiqui, M. A. | N/A | Contact-based thymidylate transfer promotes collective tumor growth | |
| 拟南芥中亲本冲突对印记基因的影响。 | Le veve, A. | N/A | The effect of parental conflict in imprinting genes in A. lyrata. | |
| 南方海獭（Enhydra lutris nereis）的理论咬合力和颌肌生长模式 | Law, C. | N/A | Growth patterns of theoretical bite force and jaw musculature in southern sea otters (Enhydra lutris nereis) | |
| 河流无脊椎动物在景观中表现出时间生态过程的空间不对称性 | Lin, X. | N/A | Riverine Invertebrates Exhibit Spatial Asymmetry in Temporal Ecological Processes Across Landscapes | |
| SbcB 以不依赖核酸外切酶的方式促进霍乱弧菌的自然转化过程。 | Dalia, T. N. | N/A | SbcB facilitates natural transformation in Vibrio cholerae in an exonuclease-independent manner | |
| 通过流形再现分析进行生成模型验证 | Lazzaro, N. | N/A | Generative Models Validation via Manifold Recapitulation Analysis | |
| 西澳大利亚城市灌木丛火灾后的兰花输家和赢家：与其他特征深度融合的响应连续体 | Brundrett, M. C. | N/A | Orchid losers and winners after fire in West Australian urban bushland: A response continuum deeply integrated with other traits | |
| TFAP2C是调节子宫内滋养层细胞侵袭和深部血绒毛膜胎盘形成的关键因子。 | Dominguez, E. M. | N/A | TFAP2C is a key regulator of intrauterine trophoblast cell invasion and deep hemochorial placentation | |
| PPD-H1通过提高抗逆性和能量代谢，在高温环境下增强花粉活力 | Lan, T. | N/A | PPD-H1 Improves Stress Resistance and Energy Metabolism to Boost Spike Fertility under High Ambient Temperatures | |
| 利用CryFold改进冷冻电镜图的自动模型构建 | Su, B. | N/A | Improved automated model building for cryo-EM maps using CryFold | |
| 来自L. meyenii Walp的脂质纳米颗粒通过多模态蛋白质冠形成减轻脓毒症 | Sung, J. J. | N/A | Lipid Nanoparticles from L. meyenii Walp Mitigate Sepsis through Multimodal Protein Corona Formation | |
| 性特异性调控芬太尼奖赏的昼夜节律转录因子NPAS2 | Barko, K. | N/A | Sex-specific Regulation of Fentanyl Reward by the Circadian Transcription Factor NPAS2 | |
| 基于神经形态成像的人类血细胞计数 | Zhang, Z. | N/A | Neuromorphic Imaging Cytometry on Human Blood Cells | |
| NOTCH3激活机制的异质性揭示了针对CADASIL的靶向治疗潜力。 | Hosseini-Alghaderi, S. S. | N/A | Heterogeneity of NOTCH3 activation mechanisms uncovers therapeutic potential for targeted therapies for CADASIL. | |
| 在早衰小鼠中，TFAM和线粒体DNA拷贝数操作引发的组织特异性反应 | Kremer, L. S. | N/A | Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice | |
| 多功能便携式Cas12a介导的抗生素抗性标记检测 | Vargas-Reyes, M. | N/A | Versatile and Portable Cas12a-mediated Detection of Antibiotic Resistance Markers | |
| 高分辨率冷冻电镜展示了肠产毒性大肠杆菌中的I型和IV型菌毛结构的水合形态。 | Nakamura, S. | N/A | High-resolution Cryo-EM visualises hydrated type I and IV pilus structures from enterotoxigenic Escherichia coli | |
| 线粒体调控巨核细胞-红细胞祖细胞的细胞命运决定 | Sung, E. | N/A | Mitochondria Regulate the Cell Fate Decisions of Megakaryocyte-Erythroid Progenitors | |
| 成熟皮下脂肪细胞中的Wnt激活通过依赖于ATGL的脂解作用导致脂肪营养不良和皮肤纤维化。 | Ma, Q. | N/A | Wnt activation in mature dermal adipocytes leads to lipodystrophy and skin fibrosis via ATGL-dependent lipolysis. | |
| 全球高致病性禽流感H5N1和H5Nx的风险地图：基于2020年以来发生的疫情事件 | Dupas, M.-C. | N/A | Global risk mapping of highly pathogenic avian influenza H5N1 and H5Nx in the light of epidemic episodes occurring from 2020 onward | |
| 自动发现最优离散字符模型 | Boyko, J. | N/A | Automatic Discovery of Optimal Discrete Character Models | |
| 一种与Haematomyzus elephantis共生的专性共生体，其基因组显著减少，类似于吸血虱中的共生细菌。 | Rihova, J. | N/A | An obligate symbiont of Haematomyzus elephantis with a strongly reduced genome resembles symbiotic bacteria in sucking lice | |
| 新型增殖相关基因标志物在微卫星稳定型结直肠癌预后中的开发与验证 | Wang, S. | N/A | Development and validation of novel proliferation-related gene signature for MSS colorectal cancer prognosis | |
| 自上而下的形状线索对半透明感知的影响 | Nagai, T. | N/A | Top-Down Effects on Translucency Perception in Relation to Shape Cues | |
| 朊病毒安全实验室拭子测试 | Simmons, S. M. | N/A | Prion safety laboratory swipe test | |
| 慢性鼻-鼻窦炎伴鼻息肉与不伴鼻息肉基因表达的比较 | Kasem, M. | N/A | Comparison of Gene Expression between Chronic Rhinosinusitis with Nasal Polyposis and without Nasal Polyposis | |
| 特米尼洛山雪中的微塑料（意大利列蒂） | Pietrelli, L. | N/A | MICROPLASTICS IN THE MOUNT TERMINILLO SNOW (RIETI, ITALY) | |
| 预测与心肌梗塞和肺癌相关的双向分子预后特征：一种计算机模拟视角 | Nandi, D. D. | N/A | Predicting Prognostic Bidirectional Molecular Signatures Associating Myocardial Infarction and Lung Cancer: An In-Silico Perspective | |
| 中性粒细胞胞外陷阱基因表达特征可识别胰腺肿瘤转移抑制的预后和可靶向信号轴 | McDonald, P. C. | N/A | Neutrophil Extracellular Trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting metastasis of pancreatic tumours | |
| 单细胞表观遗传分析揭示了与肾癌中BAP1缺陷相关的干扰素应答高水平程序 | Camp, S. Y. | N/A | Single-cell epigenetic profiling reveals an interferon response-high program associated with BAP1 deficiency in kidney cancer | |
| 比较儿童数学能力和流利度的神经认知机制：来自fNIRS研究的见解 | Yeo, A. Y. N. | N/A | Comparing neurocognitive mechanisms of mathematical ability and fluency in children: insights from an fNIRS study | |
| 时间对感觉运动适应中的一个耗时、灵活的成分和一个快速、不灵活的成分产生影响。 | Leow, L.-A. | N/A | Time affects a time-consuming, flexible component and a fast, inflexible component of sensorimotor adaptation. | |
| 蝙蝠的自组织声学行为源于简单的规则。 | Hase, K. | N/A | Self-organized acoustic behavior in bats arises from simple rules | |
| 男性创业公司创始人的年龄标准化睾酮水平在B轮融资时达到峰值 | Moradian, J. | N/A | Age-Normalized Testosterone Peaks at Series B for Male Startup Founders | |
| 生物催化领域的语言模型助手 | Nana Teukam, Y. G. | N/A | A language model assistant for biocatalysis | |
| 癌基因诱导的衰老和衰老相关分泌表型（SASP）决定了帕博西尼在PIK3CA突变型结直肠癌中的疗效。 | Cao, P. | N/A | Oncogene-induced senescence and senescence-associated secretory phenotype (SASP) determine the efficacy of palbociclib in PIK3CA mutated colorectal cancer | |
| 沿着一条欧洲小河进行的AI辅助慢性混合风险评估揭示了多个存在风险的地点，而药物是主要的驱动因素。 | Weichert, F. G. | N/A | AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers | |
| 标准流靶向蛋白质组学用于硫代葡萄糖苷生物合成途径中酶的定量 | Vik, D. | N/A | Standard-flow targeted proteomics for quantification of enzymes in glucosinolate biosynthetic pathways | |
| 网格到位置细胞连接性在十一个不同房间中的表现 | Aggarwal, A. | N/A | Grid to Place Cell Connectivity in Eleven Different Rooms | |
| 空气-液体界面精密切割肺切片（PCLS-ALI）：一种用于研究肺曲霉病的新型体外模型 | Gonzales-Huerta, L. E. | N/A | Precision-cut lung slices in air-liquid interface (PCLS-ALI): A novel ex-vivo model for the study of Pulmonary Aspergillosis | |
| 公平对待它：一种简单、快速且高效的方法，用于从死亡帽蘑菇（Amanita phalloides）中提取鹅膏毒素 | Adams, C. A. | N/A | Giving it a fair shake: A simple, fast, & efficient method to extract amatoxins from the death cap mushroom, Amanita phalloides | |
| 长期平衡选择维持了青蛙的隐秘颜色多态性 | Goutte, S. | N/A | Long-term balancing selection maintains cryptic color polymorphism in frogs | |
| 放射疗法在血液恶性肿瘤中的诱变影响和进化作用 | Diamond, B. | N/A | Mutagenic impact and evolutionary influence of radiotherapy in hematologic malignancies | |
| 通过FDR控制肽身份传播，提高差异丰度蛋白质的检测能力 | Solivais, A. J. | N/A | Improved detection of differentially abundant proteins through FDR-control of peptide-identity-propagation | |
| 静脉基因治疗可改善猫桑德霍夫病的寿命和临床结果 | Maguire, A. S. | N/A | Intravenous gene therapy improves lifespan and clinical outcomes in feline Sandhoff Disease | |
| 阿尔茨海默病中溶酶体酶基因的不足 | Benitez, B. A. | N/A | Haploinsufficiency of lysosomal enzyme genes in Alzheimers disease | |
| 标准学习与反馈延迟：来自计算模型和行为实验的见解 | Crossley, M. J. | N/A | Criterial Learning and Feedback Delay: Insights from Computational Models and Behavioral Experiments | |
| VNC-Dist：一种基于机器学习的工具，用于量化秀丽隐杆线虫腹神经索中神经元的位置 | Saharkhiz, S. | N/A | VNC-Dist: A machine learning-based tool for quantification of neuronal positioning in the ventral nerve cord of C. elegans | |
| 评估无序区域边界处多聚XYs的螺旋稳定性与MD模拟 | Goncalves-Kulik, M. | N/A | Assessing the helical stability of polyXYs at the boundaries of Intrinsically Disordered Regions with MD simulations | |
| 电场耦合使得动作电位的传导成为可能。 | Waaben, J. | N/A | Ephaptic coupling enables action potential conduction | |
| 胰岛素/胰岛素样生长因子信号通路促进果蝇雌性更高的脂肪储存 | Biswas, P. | N/A | Insulin/insulin-like growth factor signaling pathway promotes higher fat storage in Drosophila females | |
| 内侧颞叶中空间和价值的分布式编码 | Yang, L. | N/A | Distributed coding of space and valence in the medial temporal lobe | |
| 感觉历史驱动LP/丘脑枕-前额叶皮层电路中的适应性神经几何结构 | Leow, Y. N. | N/A | Sensory History Drives Adaptive Neural Geometry in LP/Pulvinar-Prefrontal Cortex Circuits | |
| 通过优化嗅觉记忆网络中的神经流形进行表征学习 | Hu, B. | N/A | Representational learning by optimization of neural manifolds in an olfactory memory network | |
| 体内类似的无支架三维体外肌肉萎缩模型：个性化医学中锚定细胞片工程的案例 | Shahin-Shamsabadi, A. | N/A | in vivo-like Scaffold-free 3D in vitro Models of Muscular Dystrophies: The Case for Anchored Cell Sheet Engineering in Personalized Medicine | |
| 黑鸟：使用合成和低覆盖率长读取进行结构变异检测 | Meleshko, D. | N/A | Blackbird: structural variant detection using synthetic and low-coverage long-reads | |
| 蛋白质晶体结构和AlphaFold预测模型的分子表面的几何特性 | Wang, L. | N/A | The geometric properties of the molecular surfaces of protein crystal structures and AlphaFold predicted models | |
| 用于增强非编码RNA分类的核苷酸序列生成方法 | Chiquitto, A. G. | N/A | Generative Approaches for Nucleotide Sequences to Enhance Non-coding RNA Classification | |
| 阐明非同义替代对人胰岛淀粉样多肽构象变化的影响 | Bashar, M. A. | N/A | Elucidating conformational alteration of human islet amyloid polypeptide by nonsynonymous substitution | |
| 在二叠纪末大灭绝后，中国低纬度地区的河流生态系统迅速恢复 | Guo, W. | N/A | Rapid riparian ecosystem recovery in low-latitudinal North China following the end-Permian mass extinction | |
| 综合心血管对分级下肢负压的剂量反应 | Whittle, R. S. | N/A | Integrative cardiovascular dose-response to graded lower body negative pressure | |
| 时间与催产素在有无妊娠糖尿病的小鼠和人类中的疗效交互作用 | Duong, T. V.-Q. | N/A | Interaction between time-of-day and oxytocin efficacy in mice and humans with and without gestational diabetes | |
| 从神经元到网络的非线性脑连接：量化、来源与定位。 | Raffaelli, G. T. | N/A | Nonlinear brain connectivity from neurons to networks: quantification, sources and localization. | |
| 预测在观看电影过程中由前额叶皮层fNIRS信号引起的全脑神经动力学 | Gao, S. | N/A | Predicting whole-brain neural dynamics from prefrontal cortex fNIRS signal during movie-watching | |
| 抑制Notch信号通路可减轻癫痫持续状态诱导的青春期大鼠脑内癫痫放电 | Yuan, P. | N/A | Inhibition of Notch Signaling Attenuates Epileptic Discharges in the Adolescent Rat Brain after Status Epilepticus Induction | |
| 脂滴蛋白Perilipin 2通过胰腺胰岛中的β细胞脂噬作用和胰高血糖素表达，对胰岛素分泌的调控至关重要。 | Liu, S. | N/A | Lipid droplet protein Perilipin 2 is critical for the regulation of insulin secretion through beta cell lipophagy and glucagon expression in pancreatic islets | |
| 毛发再生新技术：含外泌体的不同商业产品比较 | Ferrugia, G. | N/A | New technologies for hair follicle growth and regeneration: comparison between different commercial products contain exosomes | |
| Meioc-Piwil1复合物调控rRNA转录以促进精原干细胞的分化 | Kawasaki, T. | N/A | Meioc-Piwil1 complexes regulate rRNA transcription for differentiation of spermatogonial stem cells | |
| 利用基于视频的深度学习技术解析自然环境中的蜜蜂摇摆舞 | Grison, S. | N/A | Unraveling Honey Bee's Waggle Dances in Natural Conditions with Video-Based Deep Learning | |
| 湿地草甸中刈割与覆盖对蜗牛群落影响的实验比较 | Farkas, R. | N/A | Experimental comparison of mowing and mulching on snail communities in wet meadows | |
| 将性染色体系统与四足动物成年性别比例变化联系起来的群体统计学途径 | Pipoly, I. | N/A | Demographic pathways linking sex-chromosome system to adult sex ratio variation across tetrapods | |
| 幼体营养不良下的扩散进化成本 | Vibishan, B. | N/A | Costs of dispersal evolution under larval malnutrition | |
| 当性选择遇到遗传漂变：有限种群中雄性性状与雌性偏好的共同演化 | Xu, K. | N/A | When sexual selection meets genetic drift: the coevolution of male traits and female preferences in finite populations | |
| 在安第斯山脉的拟似杂交区中，阿塔佩特斯刷嘴雀（雀形目，雀科）表现出表型变异和行为隔离的弱化。 | Munoz-Quintana, G. | N/A | Phenotypic variation and weak behavioral isolation in a putative hybrid zone between Andean Atlapetes brushfinches (Passerellidae) | |
| 结合单核苷酸多态性（SNP）亲本单体型分析与强度分析，可识别出人类胚胎植入前期的减数分裂和有丝分裂非整倍体，以及频繁的片段非整倍体。 | Handyside, A. H. | N/A | Combined SNP parental haplotyping and intensity analysis identifies meiotic and mitotic aneuploidies and frequent segmental aneuploidies in preimplantation human embryos | |
| 解析cfDNA片段化模式：将染色质结构与癌症诊断敏感性相联系 | Johnston, A. D. | N/A | Unraveling cfDNA Fragmentation Patterns: Linking Chromatin Architecture to Cancer Diagnostic Sensitivity | |
| Ca2+/钙调蛋白依赖性蛋白激酶II的α和β亚型在哺乳动物睡眠中的参与有限 | Yang, W. | N/A | Limited involvement of Ca2+/calmodulin-dependent kinase II alpha and beta in mammalian sleep | |
| 含有三核苷酸重复序列的DNA通过噬菌体T7的复制体进行复制 | Lee, S.-J. | N/A | Replication of DNA containing trinucleotide repeats by the bacteriophage T7 replisome | |
| NK-92细胞对白色念珠菌的增强抗真菌活性通过甘露聚糖特异性嵌合抗原受体介导 | Yamazaki de Campos, G. | N/A | Enhanced antifungal activity of NK-92 cells against Candida albicans mediated by a mannan-specific chimeric antigen receptor | |
| 使用生成模型进行概率性脑部MR图像变换 | Rezvani, S. | N/A | Probabilistic Brain MR Image Transformation Using Generative Models | |
| 一种核酸前药能激活线粒体呼吸并延长寿命 | Anada, T. | N/A | A nucleic acid prodrug activates mitochondrial respiration and extends lifespan | |
| 小尺寸植入式神经探针，配备高效倒装芯片微型LED，用于活体光遗传学研究 | Abrantes, M. | N/A | Small form factor implantable neural probe with efficient flip chip micro LED for in vivo optogenetics | |
| 非人灵长类动物子宫各层在妊娠期间的时间依赖性材料特性和组成 | Fodera, D. M. | N/A | Time-Dependent Material Properties and Composition of the Nonhuman Primate Uterine Layers Through Gestation | |
| 利用可解释的人工智能设计高效抗生物膜、抗菌肽 | Pikalyova, K. | N/A | Design of highly potent anti-biofilm, antimicrobial peptides using explainable artificial intelligence | |
| 可解释的聚类性能指标 | Mondal, K. | N/A | Physically Interpretable Performance Metrics for Clustering | |
| Squidiff：利用扩散模型预测细胞发育及对扰动的响应 | He, S. | N/A | Squidiff: Predicting cellular development and responses to perturbations using a diffusion model | |
| Clair3-RNA：一种基于深度学习的用于长读长RNA测序数据的小变异检测工具 | Zheng, Z. | N/A | Clair3-RNA: A deep learning-based small variant caller for long-read RNA sequencing data | |
| AlphaFold 对整个基因组的预测概览 | Cazals, F. | N/A | AlphaFold predictions on whole genomes at a glance | |
| 使用综合生物信息学方法鉴定结直肠癌中的潜在枢纽基因和治疗靶点 | D, K. | N/A | Identification of Potential Hub Genes and Therapeutic Targets in Colorectal Cancer Using Integrated Bioinformatics Approaches | |
| Pharming：从肿瘤单细胞DNA测序中联合克隆树重建SNV和CNA演化 | Weber, L. L. | N/A | Pharming: Joint Clonal Tree Reconstruction of SNV and CNAEvolution from Single-cell DNA Sequencing of Tumors | |
| 基于深度学习的酶最适pH预测及通过点突变提高酸耐受性的设计 | Qiu, S. | N/A | Deep learning-based prediction of enzyme optimal pH and design of point mutations to improve acid resistance | |
| 通过机器学习分析免疫单细胞RNA-seq数据，揭示预测检查点免疫治疗反应的基因和细胞特征 | Pinhasi, A. | N/A | Uncovering Predictive Gene and Cellular Signatures for Checkpoint Immunotherapy Response through Machine Learning Analysis of Immune Single-Cell RNA-seq Data | |
| MAX2泛素连接酶-受体-底物复合体协同独脚金内酯感知机制 | Arold, S. T. | N/A | Mechanism of cooperative strigolactone perception by the MAX2 ubiquitin ligase-receptor-substrate complex | |
| RNA动力学与相分离的中等分辨率模型，显式包含Mg²⁺ | Li, S. | N/A | An Intermediate Resolution Model of RNA Dynamics and Phase Separation with Explicit Mg2+ | |
| 基因编码纳米颗粒的单颗粒追踪：优化表达以进行细胞质扩散研究 | Korunova, E. | N/A | Single Particle Tracking of Genetically Encoded Nanoparticles: Optimizing Expression for Cytoplasmic Diffusion Studies | |
| RAS通路抑制剂与靶向药物的联合在多种癌症类型中具有致癌KRAS变异的源自患者的细胞球体中表现出活性。 | Davoudi, Z. | N/A | Combinations of RAS pathway inhibitors with targeted agents are active in spheroids of patient-derived cells with oncogenic KRAS variants from multiple cancer types | |
| 工程化儿童肿瘤保留了患者肿瘤的基因型和表型，适用于精准医学。 | Jung, M. | N/A | Engineered paediatric tumours retain patient tumour genotype and phenotype for precision medicine. | |
| 线粒体基因组编码的mitomiRs调控三阴性乳腺癌中的细胞可塑性和铁死亡敏感性 | Kandettu, A. | N/A | Mitochondrial genome-encoded mitomiRs regulate cellular plasticity and susceptibility to ferroptosis in triple-negative breast cancer | |
| 通过提示语言模型实现多功能可控蛋白质生成 | Wang, Z. | N/A | Multi-purpose controllable protein generation via prompted language models | |
| 高吞吐量蛋白质组学和磷酸蛋白质组学分析的福尔马林固定石蜡包埋组织 | Haines, M. | N/A | High-throughput proteomic and phosphoproteomic analysis of formalin-fixed paraffin-embedded tissue | |
| 跨颈椎和腰椎脊髓的dI3神经元感觉运动回路图谱 | Nasiri, S. | N/A | Mapping of dI3 neuron sensorimotor circuits across the cervical and lumbar spinal cord | |
| 增强电生理学研究中从场电位提取信息的能力 | Akella, S. | N/A | Enhancing information extraction from field potentials in electrophysiology studies | |
| 同时失去CAMK2A和CAMK2B揭示了内源性体内底物 | Rigter, P. M. F. | N/A | Simultaneous loss of CAMK2A and CAMK2B reveals endogenous in vivo substrates | |
| 受损的补体调节在肺移植后驱动慢性肺移植物功能障碍。 | Kulkarni, H. S. | N/A | Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation. | |
| 孤立的小鼠成年心肌细胞表现出最低的线粒体ATP需求，并高度依赖糖酵解。 | Mattam, U. | N/A | Isolated Mouse Adult Cardiomyocytes Display Minimal Mitochondrial ATP Demand and Maximal Reliance on Glycolysis | |
| PRDM16-CtBP1/2复合物与HDAC1/2相互作用，调节神经发生转录程序并指导皮层神经元迁移 | Warren, S. | N/A | A PRDM16-CtBP1/2 Complex Interacts with HDAC1/2 to Regulate Transcriptional Programs of Neurogenesis and Guide Cortical Neuron Migration | |
| ILSM：用于分析三方交互网络互连结构的软件包 | Sun, W. | N/A | ILSM: A package for analyzing the interconnection structure of tripartite interaction networks | |
| 在温度变化条件下果蝇发育时间的阶段特异性热塑性 | Chattopadhyay, A. | N/A | Thermal Plasticity of Stage Specific Development Time in Drosophila melanogaster under Shifting Temperatures | |
| 推进远程与低资源医疗服务的进展：通过微生物活检皮肤样本在不同温度下对mRNA管家基因稳定性的分析 | Falckenhayn, C. | N/A | Advancing Remote and Low-Resource Healthcare Delivery with Microbiopsy Skin Sample mRNA Housekeeping Gene Stability Analysis Across Various Temperatures | |
| 结合体细胞突变和基因表达的综合分析揭示了在DNA损伤应答下，牙龈颊癌中与核斑点相关的增强干细胞特性 | Kumar, S. | N/A | Combined analysis of somatic mutations and gene expression reveals nuclear speckles-associated enhanced stemness in gingivobuccal carcinoma under DNA damage response | |
| 通过计算优化和结构工程显著提升接枝纳米抗体的抗病毒疗效 | HUO, L. | N/A | Significantly enhancing antiviral efficacy by computational optimization and structural engineering of grafted nanobodies | |
| 质粒、前噬菌体和防御系统从植物微生物群基因组中被耗尽 | Bograd, A. | N/A | Plasmids, Prophages and Defense Systems are Depleted from Plant Microbiota Genomes | |
| 单细胞图谱的分布保留压缩：实现隐私保护数据传播与新细胞类型发现 | Cai, Z. | N/A | Distribution-preserved compression of single-cell atlases for privacy-protected data dissemination and novel cell type discovery | |
| GOBoost：利用长尾基因本体论术语进行准确的蛋白质功能预测 | Zhang, L. | N/A | GOBoost: Leveraging Long-Tail Gene Ontology Terms for Accurate Protein Function Prediction | |
| CD73抑制子宫内膜癌中突变型β-连环蛋白的致癌活性 | Hirsch, R. M. | N/A | CD73 restrains mutant β-catenin oncogenic activity in endometrial carcinomas | |
| 酶约束的梅毒螺旋体代谢模型鉴定出甘油-3-磷酸脱氢酶作为替代电子汇 | Shahreen, N. | N/A | Enzyme-constrained Metabolic Model of Treponema pallidum Identified Glycerol-3-phosphate Dehydrogenase as an Alternate Electron Sink | |
| 人巨细胞病毒预融合样糖蛋白B亚单位疫苗在小鼠中引发的体液免疫反应与融合后gB相似 | Karthigeyan, K. P. | N/A | A human cytomegalovirus prefusion-like glycoprotein B subunit vaccine elicits similar humoral immunity to that of postfusion gB in mice | |
| 一种定量方法揭示了痘病毒感染中抗原呈递和免疫原性的普遍相关性，适用于病毒CD8+ T细胞表位 | Witney, M. J. | N/A | A quantitative approach to poxvirus infection reveals general correlates of antigen presentation and immunogenicity for viral CD8+ T cell epitopes | |
| 在金黄色葡萄球菌中，sRNA介导的细胞壁压力与半乳糖代谢之间的交叉对话 | Germain, M. | N/A | sRNA-mediated crosstalk between cell wall stress and galactose metabolism in Staphylococcus aureus | |
| 结合活细胞荧光成像与原位冷冻电子断层扫描技术，揭示了耐辐射奇异球菌（Deinococcus radiodurans）的隔膜形成过程。 | Gaifas, L. | N/A | Combining live cell fluorescence imaging with in situ cryo electron tomography sheds light on the septation process in Deinococcus radiodurans | |
| SARS-CoV-2 亚变体 KP.3.1.1 和 XEC 的抗体逃逸性 | Wang, Q. | N/A | Antibody evasiveness of SARS-CoV-2 subvariants KP.3.1.1 and XEC | |
| 结合代谢工程和发酵优化，通过Cutaneotrichosporon oleaginosus实现成本效益的油脂生产 | Duman-Ozdamar, Z. E. | N/A | Combining metabolic engineering and fermentation optimization to achieve cost-effective oil production by Cutaneotrichosporon oleaginosus | |
| 癌症相关SF3B1突变K700E导致U2/分支点识别广泛变化，但不影响剪接。 | Damianov, A. | N/A | Cancer-associated SF3B1 mutation K700E causes widespread changes in U2/branchpoint recognition without altering splicing. | |
| 生成 snoRNA 引导的可编程 2'O-甲基化 | Zhao, J. | N/A | Generating snoRNA-guided Programmable 2'O-methylation | |
| CDKL5激酶通过富含丝氨酸的C端区域进行液-液相分离，而与神经发育疾病相关的截断则会对其造成损害。 | Dell'Oca, M. | N/A | The CDKL5 kinase undergoes liquid-liquid phase separation driven by a serine-rich C-terminal region and impaired by neurodevelopmental disease-related truncations | |
| Lrif1调节Trim28介导的小鼠胚胎干细胞中Dux位点的抑制作用 | Sikrova, D. | N/A | Lrif1 modulates Trim28-mediated repression of the Dux locus in mouse embryonic stem cells | |
| 完整氨酰化tRNA的纳米孔测序 | White, L. K. | N/A | Nanopore sequencing of intact aminoacylated tRNAs | |
| 渗透压膨胀的囊泡而非中间丝上的NLRP3支架促进了炎症小体的组装 | de Paz Linares, G. A. | N/A | Scaffolding of NLRP3 on osmotically swollen vesicles but not intermediate filaments promotes inflammasome assembly | |
| 地球历史上固氮酶结构的演变 | Cuevas, B. | N/A | Nitrogenase structural evolution across Earth s history | |
| 一种用于在真菌性脑膜炎病原体新生隐球菌中进行条件性突变的生长素诱导降解系统 | Madhani, H. D. | N/A | An auxin-inducible degron system for conditional mutation in the fungal meningitis pathogen Cryptococcus neoformans | |
| 通过原位多聚腺苷酸化和空间RNA测序实现微生物群-宿主相互作用的高分辨率空间映射 | Ntekas, I. | N/A | High Resolution Spatial Mapping of Microbiome-Host Interactions via in situ Polyadenylation and Spatial RNA Sequencing | |
| 野生型和FMR1敲除的人类胚胎干细胞中核糖体的分析 | Kharbanda, T. | N/A | Analysis of ribosomes from the Wild-type and FMR1 knockout human embryonic stem cells | |
| 3-甲基胞嘧啶修饰对神经元富集的精氨酸tRNA反密码子茎的结构影响 | Berger, K. | N/A | Structural impact of 3-methylcytosine modification on the anticodon stem of a neuronally-enriched arginine tRNA | |
| 使用深度学习进行高亲和力蛋白质结合大环的精确从头设计 | Rettie, S. | N/A | Accurate de novo design of high-affinity protein binding macrocycles using deep learning | |
| 无参考分析单细胞RNA测序数据揭示了在蝾螈神经发生过程中rRNA和mtRNA转录的升高 | Ratul, M. R. Z. | N/A | Reference-free Analysis of scRNA-seq Data Reveals Elevated rRNA and mtRNA Transcription during Neurogenesis in Axolotl | |
| 高通量筛选揭示针对肺炎克雷伯菌和大肠杆菌中抗甲氧苄啶的DfrA1蛋白的潜在抑制剂 | Hasnat, S. | N/A | High-Throughput Screening Reveals Potential Inhibitors Targeting Trimethoprim-Resistant DfrA1 Protein in Klebsiella pneumoniae and Escherichia coli | |
| Sphae：一种从测序数据中自动预测噬菌体疗法候选者的工具包 | Papudeshi, B. | N/A | Sphae: An automated toolkit for predicting phage therapy candidates from sequencing data | |
| 军团菌肺炎杆菌对单一和多宿主的宿主特异性适应 | Moreno, A. B. | N/A | Host-specific adaptation of Legionella pneumophila to single and multiple hosts | |
| 回到角的问题：通过不同类型的重组事件对祖先角状态的重建。 | Upadhyay, M. | N/A | Back to the horns: a reconstruction of the ancestral horn state through distinct types of recombination events. | |
| 用于蛋白质组数据质询的归一化与方向性相互作用评分 | Poncha, K. F. | N/A | Normalized and Directional Interplay Scoring for the Interrogation of Proteoform Data | |
| TAP2蛋白变异体的鉴定，这些变异体对HSV1 ICP47蛋白的抑制具有抗性 | Nagy, G. | N/A | Identification of TAP2 protein variants resistant to inhibition by the HSV1 ICP47 protein | |
| 生物膜生活方式作为氨氧化古菌的共同特征 | Dreer, M. | N/A | Biofilm lifestyle as a common trait of ammonia-oxidizing archaea | |
| # BioRxiv 2024-11-17 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 贝叶斯球：贝叶斯方法在职业棒球击球员中的整合 | Brantley, J. A. | N/A | Bayesball: Bayesian Integration in Professional Baseball Batters | |
| p53翻译异构体Δ40p53通过调节miR-4671-5p/SGSH轴调控细胞周期 | Pal, A. | N/A | p53 translational-isoform Δ 40p53 regulates cell cycle by modulating the miR-4671-5p/SGSH axis | |
| 古代和现代伊比利亚牛的基因组中留下了野牛杂交的遗传遗产 | Günther, T. | N/A | The Genomic Legacy of Aurochs hybridization in ancient and modern Iberian Cattle | |
| 一种富含棕色脂肪的脂肪因子，ASRA，是一种瘦素受体拮抗剂，能够刺激食欲。 | Huang, L. | N/A | A brown fat-enriched adipokine, ASRA, is a leptin receptor antagonist that stimulates appetite | |
| 使用变分自编码器实现AI设计的基因组 | Dudek, N. K. | N/A | Towards AI-designed genomes using a variational autoencoder | |
| 通过集体迁徙实现的非遗传性适应 | Vo, L. | N/A | Non-genetic adaptation by collective migration | |
| 人类强化学习中对缓慢变化特征的归纳偏置 | Hedrich, N. L. | N/A | An inductive bias for slowly changing features in human reinforcement learning | |
| 全脑血流动力学预测人类在睡眠和清醒状态下的神经节律 | Jacob, L. P. L. | N/A | Brainwide hemodynamics predict neural rhythms across sleep and wakefulness in humans | |
| 定量超微结构时间线揭示了自噬在细胞核中的作用，并揭示了动力蛋白样蛋白1在核膜中的作用 | Mannino, P. J. | N/A | A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope | |
| 调控性ChREBP/14-3-3复合物的分子胶保护β细胞免受糖脂毒性影响。 | Katz, L. S. | N/A | Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity. | |
| 肾小球弹性与基因表达模式定义了Alport肾病的两个阶段 | Yoon, J. | N/A | Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy | |
| BAITSAO：基于语言模型的药物协同分析基础模型构建 | Liu, T. | N/A | BAITSAO: Building A Foundation Model for Drug Synergy Analysis Powered by Language Models | |
| 在不同黄鲈（Perca flavescens）种群中，有效种群大小变化背景下发生的平行遗传适应 | Yin, X. | N/A | Parallel genetic adaptation amidst a background of changing effective population sizes in divergent yellow perch (Perca flavescens) populations | |
| 心灵字幕：从人脑活动中演化出心理内容的描述性文本 | Horikawa, T. | N/A | Mind Captioning: Evolving descriptive text of mental content from human brain activity | |
| 导致精神病的损伤在大脑海马中映射到一条共同的脑回路 | Pines, A. R. | N/A | Lesions that Cause Psychosis Map to a Common Brain Circuit in the Hippocampus | |
| 静水压力与肌动蛋白聚合的联合作用驱动内皮尖端细胞迁移和发芽血管生成 | Kondrychyn, I. | N/A | Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis | |
| 基于CRISPRi的微胶质细胞自闭症谱系障碍风险基因筛选揭示了ADNP在微胶质细胞内吞作用和突触修剪中的作用 | Teter, O. M. | N/A | CRISPRi-based screen of Autism Spectrum Disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning | |
| 微生物间的相互作用影响抗生素抗性演化的速度和模式。 | Zandbergen, L. E. | N/A | Microbial interactions affect the tempo and mode of antibiotic resistance evolution | |
| 理解深度药物反应模型性能的来源揭示了见解和改进 | Branson, N. | N/A | Understanding the Sources of Performance in Deep Drug Response Models Reveals Insights and Improvements | |
| 在高分辨率和高准确度下对听觉中脑的神经编码进行建模 | Drakopoulos, F. | N/A | Modeling neural coding in the auditory midbrain with high resolution and accuracy | |
| 探究自然脑动力学拓扑结构中的个体差异 | Xian, J. | N/A | Probing Individual Differences in the Topological Landscape of Naturalistic Brain Dynamics | |
| 乙烯受体获得和丧失功能突变体揭示了根中依赖于ETR1的转录网络 | Khoury, M. G. | N/A | Ethylene Receptor Gain- and Loss-of-function Mutants Reveal an ETR1-dependent Transcriptional Network in Roots | |
| 一种高效预测自然物体感知相似性的高通量方法 | Kaniuth, P. | N/A | A high-throughput approach for the efficient prediction of perceived similarity of natural objects | |
| 在异源二倍体和四倍体种群中，基因组预测杂种优势、近交控制和配对分配 | Endelman, J. B. | N/A | Genomic prediction of heterosis, inbreeding control, and mate allocation in outbred diploid and tetraploid populations | |
| 活性树突化学突触与间隙连接的细胞外信号之间的二分法 | Sirmaur, R. | N/A | Dichotomy between extracellular signatures of active dendritic chemical synapses and gap junctions | |
| 突触前囊泡循环中的幂律适应 | Mikulasch, F. A. | N/A | Power-law adaptation in the presynaptic vesicle cycle | |
| 重复激活视前区接收神经元在室旁核后部介导慢性热诱导的负性情绪效价和过度唤醒状态 | Cao, Z. | N/A | Repeated activation of preoptic area-recipient neurons in posterior paraventricular nucleus mediates chronic heat-induced negative emotional valence and hyperarousal states | |
| 交配系统对多个属中谱系分化的影响分析 | Xu, K. | N/A | Analysis of the effects of mating systems on lineage diversification across multiple genera | |
| 用于多胺的基因编码荧光报告器 | Sharma, P. | N/A | Genetically encoded fluorescent reporter for polyamines | |
| 主要抑郁症的基因年龄差距估计（GAGE）：使用基因表达的惩罚性生物年龄模型 | Li, Y. | N/A | Gene Age Gap Estimate (GAGE) for major depressive disorder: a penalized biological age model using gene expression | |
| 在肿瘤发生过程中，mRNA的等位基因失衡被选择性地保留，这一现象源于表观遗传的改变，并且与预后相关。 | Palou-Marquez, G. | N/A | Allele imbalance in mRNA is selected in tumorigenesis, results from epigenetic alterations and has prognostic relevance | |
| 横断面脑龄评估在预测未来脑变化方面存在局限性。 | Korbmacher, M. | N/A | Cross-sectional brain age assessments are limited in predicting future brain change | |
| 通过基因组和线粒体数据揭示的濒危物种西伯利亚鼯鼠（Pteromys volans）的种群结构 | Ito dos Santos, F. | N/A | Population structure of the endangered Siberian flying squirrel (Pteromys volans) revealed by genomic and mitochondrial data | |
| 弥合秀丽隐杆线虫的连接组与全脑活动之间的差距 | Creamer, M. S. | N/A | Bridging the gap between the connectome and whole-brain activity in C. elegans | |
| 过滤点过程可有效捕捉神经电生理记录中的节奏性和宽带功率谱结构 | Bloniasz, P. F. | N/A | Filtered Point Processes Tractably Capture Rhythmic And Broadband Power Spectral Structure in Neural Electrophysiological Recordings | |
| 利用光谱流式细胞术对全细胞中核组蛋白H3的翻译后修饰进行分析 | Golden, C. S. | N/A | Nuclear Histone H3 Post-translational Modification Profiling in Whole Cells using Spectral Flow Cytometry | |
| 通过拓扑高阶功能连接解析精神分裂症中的整合-分离失衡 | Li, Q. | N/A | Unraveling Integration-Segregation Imbalances in Schizophrenia Through Topological High-Order Functional Connectivity | |
| ASCL1介导的染色质结合和基因激活的增殖性与神经元程序具有细胞周期阶段特异性 | Beckman, W. F. | N/A | Distinct proliferative and neuronal programmes of chromatin binding and gene activation by ASCL1 are cell cycle stage-specific | |
| LipiDetective - 一种用于在串联质谱中识别分子脂质种类的深度学习模型 | Wuerf, V. | N/A | LipiDetective - a deep learning model for the identification of molecular lipid species in tandem mass spectra | |
| 代谢物营养图谱指南（MeNu GUIDE）——一种用于揭示与疾病病因相互作用的代谢物营养图谱 | Wuerf, V. | N/A | MeNu GUIDE - a metabolite nutrition graph to uncover interactions with disease etiology | |
| sv-channels：使用一维卷积神经网络过滤基因组删除 | Santuari, L. | N/A | sv-channels: filtering genomic deletions using one-dimensional convolutional neural networks | |
| 节奏与背景（RnB）：睡眠记录的光谱分析 | Dube, J. | N/A | Rhythms and Background (RnB): The Spectroscopy of Sleep Recordings | |
| 利用语言引导的视觉模型进行空间蛋白质组学的广义细胞表型分析 | Wang, X. | N/A | Generalized cell phenotyping for spatial proteomics with language-informed vision models | |
| 较长的内含子往往含有更多的串联重复序列，并且更频繁地经历插入和删除，这些插入和删除大多发生在编码蛋白质的内在无序区域。 | Homma, K. | N/A | Longer internal exons tend to have more tandem repeats and more frequently experience insertions and deletions that are mostly in intrinsically disordered regions of the encoded proteins | |
| 长期服用裸盖菇素对前额-纹状体-丘脑回路动态性和有效性连接的影响 | Pasquini, L. | N/A | Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic circuits | |
| 减少功能缺陷的老化造血干细胞（HSCs）可减轻老年受体小鼠的衰老相关表型 | Wang, Y. | N/A | Reducing functionally defective old HSCs alleviates aging-related phenotypes in old recipient mice | |
| 从人类诱导多能干细胞（iPSCs）生成形态上不同的星形胶质细胞亚型揭示了胶质形态、功能和反应性之间的联系 | O'Toole, K. | N/A | Generation of morphologically distinct astrocyte subtypes from human iPSCs reveals a link between glial shape, function and reactivity | |
| 核糖体丰度而非同源基因组成对于生殖系发育至关重要 | Grobicki, K. Z. A. | N/A | Ribosome abundance, not paralogue composition, is essential for germline development | |
| CPSM：用于预测单个癌症患者生存概率的自动化机器学习管道R包 | Kaur, H. | N/A | CPSM: R-package of an Automated Machine Learning Pipeline for Predicting the Survival Probability of Single Cancer Patient | |
| 上游开放阅读框在果蝇进化和发育过程中缓冲翻译变异性 | Sun, Y. | N/A | Upstream open reading frames buffer translational variability during Drosophila evolution and development | |
| AlphaRING: 通过蛋白质建模和残基相互作用网络分析进行错义变异分类 | Logsdon, A. | N/A | AlphaRING: Missense Variant Classification via Protein Modelling and Residue Interaction Network Analysis | |
| 首次为三种海葵（珊瑚纲：海葵目）宿主物种生成了从头组装的HiFi基因组 | De Jode, A. | N/A | The first de novo HiFi genome assemblies for three clownfish-hosting sea anemone species (Anthozoa: Actiniaria) | |
| 从Hi-C数据解读跨物种的3D基因组结构 | Shkolikov, A. | N/A | Deciphering the 3D genome organization across species from Hi-C data | |
| 雪貂乳腺内感染牛H5N1流感病毒导致哺乳期新生儿传播和死亡 | Baker, P. H. | N/A | Intramammary infection of bovine H5N1 influenza virus in ferrets leads to transmission and mortality in suckling neonates | |
| 在肠道微生物群中，通过衣壳介导的大规模细菌基因组DNA的移动 | Borodovich, T. | N/A | Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome | |
| 人类中枢神经系统中的体感高频振荡 | Bailey, E. | N/A | Somatosensory high frequency oscillations across the human central nervous system | |
| 很少是绝对的，总是高维的：神经代码如何随着皮层层次的变化而变化 | Posani, L. | N/A | Rarely categorical, always high-dimensional: how the neural code changes along the cortical hierarchy | |
| 产后中缝背侧核对脊髓内侧深背侧角RORβ中间神经元的5-羟色胺调节的成熟过程 | West, C. W. | N/A | Postnatal maturation of serotonergic modulation of spinal RORβ interneurons in the medial deep dorsal horn | |
| 揭示动态人脑相位一致性网络 | Olsen, A. S. | N/A | Uncovering dynamic human brain phase coherence networks | |
| 一种基于视紫红质的新型电压指示剂，用于在体内同时进行双光子光学记录与GCaMP | Villette, V. | N/A | A novel rhodopsin-based voltage indicator for simultaneous two-photon optical recording with GCaMP in vivo | |
| Gria3突变小鼠（一种精神分裂症的遗传动物模型）中脑区特异性改变及活动调节基因的失调 | Huang, W.-C. | N/A | Brain-region-specific changes and dysregulation of activity regulated genes in Gria3 mutant mice, a genetic animal model of schizophrenia | |
| 终纹床核的促肾上腺皮质激素释放因子神经元在性别和动情周期阶段上表现出依赖性的突触活动差异，以及在焦虑增强的惊跳反应中的作用差异。 | Chudoba, R. | N/A | Corticotropin-releasing factor neurons of the bed nucleus of the stria terminalis demonstrate sex- and estrous phase-dependent differences in synaptic activity and in their role in anxiety-potentiated startle | |
| 淀粉样β寡聚体引起的社交和情境记忆障碍通过Sigma-1受体激活得以恢复 | Djebari, S. | N/A | Social and Contextual Memory Impairments Induced by Amyloid-β Oligomers are Rescued by Sigma-1 Receptor Activation | |
| 单个神经元对特定模态和非模态语言的处理 | Yair, L. | N/A | Modality-Specific and Amodal Language Processing by Single Neurons | |
| 激活下丘脑-脑桥-脊髓通路促进小鼠脊髓损伤后的运动启动和功能恢复 | Li, Y. | N/A | Activation of hypothalamic-pontine-spinal pathway promotes locomotor initiation and functional recovery after spinal cord injury in mice | |
| 外侧下丘脑中的皮层输入整合主要由内侧前额叶皮层主导。 | Razenberg, L. J. A. M. | N/A | Integration of cortical inputs in the lateral hypothalamus is dominated by the medial prefrontal cortex | |
| 时钟基因period和timeless控制果蝇运动终末的突触发生 | Ferreiro, M. J. | N/A | Clock genes period and timeless control synaptogenesis in Drosophila motor terminals | |
| 在人类真菌病原体的形态发生过程中，细胞质的动态流动性 | Serrano, A. | N/A | Dynamic cytoplasmic fluidity during morphogenesis in a human fungal pathogen | |
| 使用无基因模型对发育细胞命运转变进行定量引导 | Hajji, I. | N/A | Quantitative guiding of developmental cell fate transitions using gene-free modelling | |
| 早期运动干扰了斑马鱼鳍再生过程中促进修复的细胞外基质程序 | Lewis, V. M. | N/A | Early exercise disrupts a pro-repair extracellular matrix program during zebrafish fin regeneration | |
| 人类滋养层干细胞和胎盘中的染色体不稳定性 | Wang, D. | N/A | Chromosomal Instability in Human Trophoblast Stem Cells and Placentas | |
| 在一种模型刺胞动物-藻类共生关系中，若缺乏异养性摄食，无性后代发育过程中共生关系会瓦解。 | Bedgood, S. A. | N/A | Symbiosis collapses during development of asexual offspring in the absence of heterotrophic feeding in a model cnidarian-algal symbiosis | |
| 通过四种方案在类器官中重建人类脑细胞多样性 | Naas, J. | N/A | Reconstitution of Human Brain Cell Diversity in Organoids via Four Protocols | |
| 无偏倚的多能性景观分析揭示了克隆命运偏倚的空间调节因子 | Erickson, A. G. | N/A | Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases | |
| 无偏倚的多能性景观分析揭示了克隆命运偏倚的空间调节因子 | Erickson, A. G. | N/A | Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases | |
| 全脑因果连接在解码神经反馈中的作用：一项元研究 | Arab, F. | N/A | Whole-brain causal connectivity during decoded neurofeedback: a meta study | |
| 使用可穿戴设备信号的婴幼儿自动持续注意力预测方法，尽快完成翻译。 | Zhang, Y. | N/A | ASAP: An automatic sustained attention prediction method for infants and toddlers using wearable device signals | |
| 结合神经绘画与转录组学揭示22q11.2缺失的细胞类型特异性形态和分子特征 | Tegtmeyer, M. | N/A | Combining NeuroPainting with transcriptomics reveals cell-type-specific morphological and molecular signatures of the 22q11.2 deletion | |
| 右侧后部θ波反映了在目标导向导航过程中，人类海马旁区因显著线索而发生的相位重置。 | Güth, M. R. | N/A | Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation | |
| 热休克因子1调控跨物种的睡眠-觉醒周期 | Yamazaki, S. | N/A | Heat Shock Factor 1 Governs Sleep-Wake Cycles Across Species | |
| 在PS19小鼠中上调ANKHD1表达可减少Tau蛋白磷酸化，并缓解Tau毒性引起的认知功能障碍。 | Tian, X. | N/A | Upregulating ANKHD1 in PS19 mice reduces Tau phosphorylation and mitigates Tau-toxicity-induced cognitive deficits | |
| 无意识和有意识视觉处理的神经相关性 | Menetrey, M. Q. | N/A | Neural correlates of unconscious and conscious visual processing | |
| 小脑白质发育受依赖于fractalkine的小胶质细胞对少突胶质前体细胞的吞噬作用调控。 | Chappell, M. K. | N/A | Cerebellar white matter development is regulated by fractalkine-dependent microglia phagocytosis of oligodendrocyte progenitor cells | |
| 可以高效地从牛胚胎发育的不同阶段获得原始牛胚胎干细胞系，并且这些细胞系具有相似的分子特征。 | Guiltinan, C. | N/A | Primed bovine embryonic stem cell lines can be derived at diverse stages of blastocyst development with similar efficiency and molecular characteristics | |
| 保守的蚜虫唾液化学感觉蛋白效应子Mp10通过靶向植物细胞膜上的AMSH去泛素化酶来抑制模式触发的免疫 | Gravino, M. | N/A | The conserved aphid saliva chemosensory protein effector Mp10 targets plant AMSH deubiquitinases at cellular membranes to suppress pattern-triggered immunity | |
| TaMYB7-A1的自然变异调控小麦对PHS的抗性并特化其地理适应性 | Wang, H. | N/A | Natural variations of TaMYB7-A1 regulate PHS resistance and specify wheat geographic adaptation | |
| 增强型肠道上皮共培养模型与轨道机械刺激：在食品纳米毒理学中的概念验证应用 | Santoni, M. | N/A | Enhanced Intestinal Epithelial Co-Culture Model with Orbital Mechanical Stimulation: A Proof-of-Concept Application in Food Nanotoxicology | |
| 比较功能性磁共振成像揭示了狗和人类在视觉皮层功能组织上对于生命感知存在的差异 | Farkas, E. B. | N/A | Comparative fMRI reveals differences in the functional organization of the visual cortex for animacy perception in dogs and humans | |
| 转译抑制剂与铜离子协同作用，增强抗生素活性 | Vazquez-Hernandez, M. | N/A | Trans-Translation inhibitors and copper ions synergize for enhanced antibiotic activity | |
| 糖磷酸介导的肽聚糖前体合成抑制 | Keller, M. R. | N/A | Sugar phosphate-mediated inhibition of peptidoglycan precursor synthesis | |
| 用于开发靶向IPNv VP2蛋白纳米抗体的小说库组装技术 | Pino-Belmar, C. | N/A | Novel Library Assembly Technique for Developing Nanobodies Targeting IPNv VP2 Protein | |
| SAM转甲基化途径和腺苷再循环生成ATP对于系统性调节和免疫反应至关重要。 | Nedbalova, P. | N/A | SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response | |
| 温度和溶解有机物塑造了亚北极海中海洋原核生物的活动和基因表达 | Amnebrink, D. | N/A | Temperature and dissolved organic matter shape marine prokaryotic activity and gene expression in a sub-arctic sea | |
| AACDB：抗原-抗体复合物数据库——一个全面的数据库，揭示相互作用界面的洞察力 | Zhou, Y. | N/A | AACDB: Antigen-Antibody Complex Database -- a Comprehensive Database Unlocking Insights into Interaction Interface | |
| 视觉训练诱导的人类枕叶快速睡眠纺锤体聚集现象通过全夜高清脑电图记录揭示 | Gervan, P. | N/A | Visual training induced occipital fast sleep spindle clustering in humans revealed by full-night HD-EEG recordings | |
| 通过昼夜节律转录因子NPAS2调节雄性和雌性小鼠中的芬太尼奖赏机制 | Barko, K. | N/A | Regulation of Fentanyl Reward in Male and Female Mice by the Circadian Transcription Factor NPAS2 | |
| 任务期间个体大脑活动模式由不同的静息态网络预测，这些网络可能反映了局部神经生物学特征。 | Scholz, R. | N/A | Individual brain activity patterns during task are predicted by distinct resting-state networks that may reflect local neurobiological features | |
| 前运动核HVC中神经活动的时间和刻板序列传播的生物物理网络建模 | Diab, Z. B. | N/A | Biophysical network modeling of temporal and stereotyped sequence propagation of neural activity in the premotor nucleus HVC | |
| AcrVIB1通过促进无功能的crRNA结合，使其易受RNase攻击，从而抑制CRISPR-Cas13b免疫。 | Wandera, K. G. | N/A | AcrVIB1 inhibits CRISPR-Cas13b immunity by promoting unproductive crRNA binding accessible to RNase attack | |
| 快速行进至分支形态 | Kriuchechnikova, A. N. | N/A | Fast marching to branching morphologies | |
| CB1和CB2受体在调节母体免疫激活和围产期大麻素暴露对认知影响的方面表现出差异性作用。 | Mackie, K. | N/A | CB1 and CB2 receptors differentially modulate the cognitive impact of maternal immune activation and perinatal cannabinoid exposure | |
| 连接图谱和基于扰动的敏感性分析识别出MEK抑制剂作为人类肺成纤维细胞中的衰老抑制剂 | Nayeri Rad, A. | N/A | Connectivity Map and perturbation-based sensitivity analysis identifies MEK inhibitors as senolytics in human lung fibroblasts | |
| 尖生长细胞的形态动力学 | Jones, G. W. | N/A | Morphodynamics of tip growing cells | |
| 热激触发的小孢子转录重编程破坏了甘蓝型油菜花粉发育进程 | Lohani, N. | N/A | Heat-Triggered Transcriptional Reprogramming in Microspores Disrupts Progression of Pollen Development in Brassica napus L. | |
| 靶向DNA ADP-核糖基化在细菌中触发模板修复，在真核生物中引发碱基突变 | Patinios, C. | N/A | Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes | |
| 荧光假单胞菌中遗传电路的动力学 | Rico, J. | N/A | Dynamics of genetic circuits in Pseudomonas protegens | |
| 谷氨酸受体依赖的海马神经元细胞质酸化涉及从细胞外空间被动流入的质子。 | Pedersen, S. E. | N/A | Glutamate receptor-dependent cytosolic acidification in hippocampal neurons involves passive flux of protons from the extracellular space | |
| 干扰素Epsilon通过自分泌的细胞内信号传导保护上皮屏障免受病毒感染 | Casazza, R. L. | N/A | Interferon Epsilon Protects Epithelial Barriers from Viral Infection through Autocrine Intracellular Signaling | |
| 鉴定调控食道过敏性炎症的神经免疫回路 | Kellerman, K. | N/A | Identification of a Neuroimmune Circuit that Regulates Allergic Inflammation in the Esophagus | |
| IL-33通过恢复体液免疫来预防复发性艰难梭菌感染。 | naz, f. | N/A | IL-33 protects from recurrent C. difficile infection by restoration of humoral immunity | |
| 通过成像质谱流式细胞术对细胞外基质进行表型分析，确定了与过敏性气道炎症相关的不同细胞外基质环境。 | Parkinson, J. E. | N/A | Extracellular matrix phenotyping by imaging mass cytometry defines distinct cellular matrix environments associated with allergic airway inflammation. | |
| 一种伴有婴儿肠结肠炎的自发性炎症动物模型 | Kang, Z. | N/A | An animal model for autoinflammation with infantile enterocolitis | |
| 鼻病毒作为严重哮喘儿童气道T细胞动态的驱动因素 | Bryant, N. | N/A | Rhinovirus as a Driver of Airway T-Cell Dynamics in Children with Severe Asthma | |
| 肠道细菌Bacteroidales的适应性变化有助于其与溶菌性噬菌体的稳定共存。 | Cortes-Martin, A. | N/A | Adaptations in gut Bacteroidales facilitate stable co-existence with their lytic bacteriophages | |
| 尼日利亚夸拉州伊洛林大都会区养殖鱼类中迟缓爱德华菌的抗菌敏感性特征 | OLABISI, F. O. | N/A | ANTIMICROBIAL SUSCEPTIBILITY PROFILE OF Edwardsiella tarda FROM FARMED FISH IN ILORIN METROPOLIS, KWARA STATE NIGERIA | |
| 有益细菌枯草芽孢杆菌（B. subtilis）的生物膜和浮游细胞在应对原生动物捕食者痢疾内变形虫（Entamoeba histolytica）时采用的不同应对策略。 | Kolodkin-Gal, I. | N/A | Differential coping strategies exerted by biofilm and planktonic cells of the beneficial bacterium B. subtilis in response to the protozoan predator Entamoeba histolytica. | |
| 博茨瓦纳、加蓬、肯尼亚、南非和美国非洲象体内潜伏的象内皮嗜性疱疹病毒和象伽玛疱疹病毒感染情况 | Pearson, V. R. | N/A | Quiescent Infections of Elephant Endotheliotropic Herpesviruses and Elephant Gammaherpesviruses in African Elephants in Botswana, Gabon, Kenya, South Africa and USA | |
| 猎物移动影响虚拟二营养级系统中捕食者专业技能的获取 | Fraser Franco, M. | N/A | Prey movement shapes the acquisition of predator expertise in a virtual bi-trophic system | |
| 在具有角色间速率变化的Mkv模型上 | Capobianco, A. | N/A | On the Mkv Model with Among-Character Rate Variation | |
| 尼莫知道：小丑鱼能够区分细小和广阔地理尺度上的隐秘宿主物种，并揭示了小丑鱼与其宿主海葵之间潜在的适应性辐射。 | Chiodo, T. | N/A | Nemo knows: clownfishes differentiate cryptic host species across fine and broad geographic scales and reveal a potential adaptive radiation in the clownfish-hosting sea anemones. | |
| 非洲无花果蝇（Zaprionus indianus）在温带地区定居后翅膀尺寸的快速进化 | Gray, W. J. | N/A | Rapid wing size evolution in African fig flies (Zaprionus indianus) following temperate colonization | |
| HSP90 缓冲了 BRCA1 中的有害遗传变异 | Gracia, B. | N/A | HSP90 buffers deleterious genetic variations in BRCA1 | |
| GWAC：一种在数据受限物种中识别功能变异的机器学习方法 | Sharo, A. G. | N/A | GWAC: A machine learning method to identify functional variants in data-constrained species | |
| 用于多组学分析样品制备的单个微流控装置 | Ravi Kumar, R. K. | N/A | A single microfluidic device for multi-omics analysis sample preparation | |
| 在微流控人体皮肤等效物中以单细胞分辨率复制动态免疫反应 | Hindle, S. A. | N/A | Replicating dynamic immune responses at single-cell resolution within a microfluidic human skin equivalent | |
| 基于结构的模拟的前瞻性评估揭示了其预测激酶突变对抑制剂结合影响的能力 | Singh, S. | N/A | Prospective evaluation of structure-based simulations reveal their ability to predict the impact of kinase mutations on inhibitor binding | |
| OncotreeVIS - 一种用于可视化突变树队列的交互式图形用户界面 | Baciu-Dragan, M. A. | N/A | OncotreeVIS - an interactive graphical user interface for visualizing mutation tree cohorts | |
| 靶向TEAD的小分子通过诱导辅因子转换来调节Hippo通路 | Guarnaccia, A. D. | N/A | TEAD-targeting small molecules induce a cofactor switch to regulate the Hippo pathway | |
| 单细胞分辨率的空间分析：抗原呈递型癌症相关成纤维细胞微环境的解析 | Chen, X. | N/A | Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches | |
| 鉴定MRTFA/SRF通路作为癌症中静止状态的关键调节因子。 | Panesso-Gomez, S. | N/A | Identification of the MRTFA/SRF pathway as a critical regulator of quiescence in cancer. | |
| 池塘和池塘养殖的吉富罗非鱼微生物组动态 | Delamare-Deboutteville, J. | N/A | Microbiome Dynamics in Tank- and Pond-Reared GIFT Tilapia | |
| 染色体工程恢复含有复杂染色体8重排的细胞的整倍性 | Lee, S. N. | N/A | Chromosome engineering to restore euploidy in cells harboring a complex rearrangement of chromosome 8 | |
| 西部斜坡割喉鳟（Oncorhynchus lewisi）的基因组组装揭示了其与虹鳟之间存在种间染色体重排。 | Flores, A.-M. | N/A | The genome assembly of the westslope cutthroat trout, Oncorhynchus lewisi, reveals interspecific chromosomal rearrangements with the rainbow trout | |
| PanTax：利用泛基因组图谱对宏基因组数据进行菌株水平分类 | Zhang, W. | N/A | PanTax: Strain-level taxonomic classification of metagenomic data using pangenome graphs | |
| CellPatch：一种高效的基础模型，用于单细胞转录组学，采用启发式补丁方法 | Wu, H.-J. | N/A | CellPatch: a Highly Efficient Foundation Model for Single-Cell Transcriptomics with Heuristic Patching | |
| 滤泡性淋巴瘤和慢性淋巴细胞白血病在单细胞分辨率下的增殖微环境 | Ferreira, A. P. | N/A | The follicular lymphoma and chronic lymphocytic leukemia proliferative microenvironment at single-cell resolution | |
| 跨组织图注意力网络用于半监督基因表达预测 | Wang, S. | N/A | Cross-tissue Graph Attention Networks for Semi-supervised Gene Expression Prediction | |
| 基于神经形态成像的人血细胞计数法 | Zhang, Z. | N/A | Neuromorphic Imaging Cytometry on Human Blood Cells | |
| # BioRxiv 2024-11-16 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 瘤胃微生物群中的抗病毒防御系统 | Saenz, J. S. | N/A | Antiviral defence systems in the rumen microbiome | |
| LIMPACAT：利用全切片成像的肝癌免疫预测多组学注意力变压器 | Chiu, Y. J. | N/A | LIMPACAT : Multi-Omics Attention Transformer for Immune Prediction in Liver Cancer Using Whole-Slide Imaging | |
| 对紫杉树进行多重扰动揭示了隐藏的蛋白质，这些蛋白质能够实现巴卡亭III和紫杉醇前体的全生物合成。 | McClune, C. J. | N/A | Multiplexed perturbation of yew reveals cryptic proteins that enable a total biosynthesis of baccatin III and Taxol precursors | |
| 从单细胞数据中推断细胞类型特异性的共表达基因 | Shan, X. | N/A | Inferring Cell-Type-Specific Co-Expressed Genes from Single Cell Data | |
| 用于植物基因组大小估计的流式细胞仪标准的重新校准 | Soni, A. | N/A | Re-calibration of flow cytometry standards for plant genome size estimation | |
| 海洛因和甲基苯丙胺戒断患者的大脑形态学改变及大脑网络形态学紊乱 | Zhou, X. | N/A | Morphological brain alterations and morphological brain network disorganizations in heroin and methamphetamine abstinent patients | |
| 可卡因使用障碍中的功能连接改变：三重网络模型和成瘾神经临床评估框架的见解 | Xu, Z. | N/A | Functional Connectivity Alterations in Cocaine Use Disorder: Insights from the Triple Network Model and the Addictions Neuroclinical Assessment Framework | |
| 注意依赖的属性比较是眶额皮层中多属性决策的基础 | Perkins, A. Q. | N/A | Attention-dependent attribute comparisons underlie multi-attribute decision-making in orbitofrontal cortex | |
| Sortilin C末端片段沉积描绘了阿尔茨海默病中与缠结相关的非淀粉样神经炎斑块的生长 | Zhang, Q.-L. | N/A | Sortilin C-terminal fragment deposition depicts tangle-related nonamyloid neuritic plaque growth in Alzheimers disease | |
| WMH-DualTasker：一种具有自监督一致性的双任务深度学习模型，用于白质高信号的自动分割与视觉评分——一项多中心研究 | Wu, Y. | N/A | WMH-DualTasker: A Dual-Task Deep Learning Model with Self-supervised Consistency for Automated Segmentation and Visual Rating of White matter Hyperintensities - a Multicentre study | |
| I型干扰素信号增强卡因酸诱导的癫痫严重程度 | Ma, J.-H. | N/A | Type I interferon signaling enhances kainic acid-induced seizure severity | |
| 小鼠的热适应需要视前区BDNF神经元及突触后增强作用 | Chen, B. | N/A | Heat Acclimation in Mice Requires Preoptic BDNF Neurons and Postsynaptic Potentiation | |
| 化学遗传学破坏齿状门导致癫痫和空间记忆缺陷 | Adam, C. D. | N/A | Chemogenetic Breakdown of the Dentate Gate Causes Seizures and Spatial Memory Deficits | |
| 青少年高脂饮食和心理社会压力对成年雄性Lewis大鼠神经内分泌应激反应及暴食行为的影响 | Sierra, J. | N/A | Impact of adolescent high-fat diet and psychosocial stress on neuroendocrine stress responses and binge eating behavior in adult male Lewis rats | |
| PrP 在体内的周转以及朊病毒疾病治疗药物起效的时间 | Corridon, T. L. | N/A | PrP turnover in vivo and the time to effect of prion disease therapeutics | |
| 慢性病毒再激活及其相关宿主免疫反应和急性COVID-19及COVID-19后遗症的临床结果 | Maguire, C. | N/A | Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19 | |
| 通过多样性生成逆转录元件在肠道微生物组中进行靶向蛋白质进化 | Macadangdang, B. R. | N/A | Targeted protein evolution in the gut microbiome by diversity-generating retroelements | |
| 海洋细菌群落中出乎意料的高水平抗生素抗性无法仅通过城市河流排放来解释 | Chan, B. W. | N/A | Unexpected levels of antibiotic resistance in marine bacterial communities not solely explained by urban river discharge | |
| 牛H5N1流感病毒感染通过乳汁传播，导致哺乳期新生儿的死亡。 | Baker, P. H. | N/A | Bovine H5N1 influenza virus infection is transmitted by milk causing mortality in suckling neonates | |
| 加纳热带稀树草原地区牛群中Q热传播的动态分析。 | Otoo, D. | N/A | Dynamic analysis of Q-fever transmission among cattle in the Tropical Savannah Grassland zone of Ghana. | |
| Arv1与并调控念珠菌GPI生物合成的第一步相互作用 | Komath, S. S. | N/A | Arv1 interacts with and regulates the first step of GPI biosynthesis in Candida albicans | |
| 源自副干酪乳杆菌CNCM I-5220的后生元可缓解皮肤炎症并保护皮肤屏障完整性。 | Pimazzoni, S. | N/A | Lactobacillus paracasei CNCM I-5220-derived postbiotic counteracts skin inflammation and protects skin barrier integrity | |
| 利用深度学习在古菌组中发现的抗生素 | Torres, M. D. T. | N/A | Discovery of antibiotics in the archaeome using deep learning | |
| 从囊性纤维化呼吸系统感染中分离的金黄色葡萄球菌种群的种内多样性 | Alexander, A. M. | N/A | Intraspecific Diversity of Staphylococcus aureus Populations Isolated from Cystic Fibrosis Respiratory Infections | |
| 布鲁氏菌感染小鼠组织代谢组学分析 | Ponzilacqua-Silva, B. | N/A | Metabolomic Analysis of Murine Tissues Infected with Brucella melitensis | |
| 奥罗波奇病毒感染人胎盘外植体和滋养层类器官 | Megli, C. | N/A | Oropouche virus infects human placenta explants and trophoblast organoids | |
| 绘制人类肠道细菌中农药诱导的代谢变化图谱 | Chen, L. | N/A | Mapping Pesticide-Induced Metabolic Alterations in Human Gut Bacteria | |
| 线粒体甲基化潜能调控线粒体核糖体组装 | Glasgow, R. I. C. | N/A | The mitochondrial methylation potential gates mitoribosome assembly | |
| miRNA在果蝇中靶向作用的生化原理 | Vega-Badillo, J. | N/A | Biochemical principles of miRNA targeting in flies | |
| 以植物为基础的疫苗接种表达弓形虫SAG1与植物HSP90融合蛋白在羔羊中引发保护性免疫反应 | Campero, L. M. | N/A | Immunization with Plant-based Vaccine Expressing Toxoplasma gondii SAG1 Fused to Plant HSP90 Elicits Protective Immune Response in Lambs | |
| 促进解离设计使得对细胞因子信号持续时间的控制成为可能 | Broerman, A. J. | N/A | Design of facilitated dissociation enables control over cytokine signaling duration | |
| 将选择性紫色杆菌素途径酶封装在1,2-丙二醇利用细菌微区室中以转移途径通量 | Palmero, B. J. | N/A | Encapsulation of Select Violacein Pathway Enzymes in the 1,2-Propanediol Utilization Bacterial Microcompartment to Divert Pathway Flux | |
| 在肠道微生物群中，通过衣壳介导的大规模细菌基因组DNA的移动 | Borodovich, T. | N/A | Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome | |
| 在灌丛和林地生境中，野火后土壤病毒和原核生物群落发生了显著变化。 | Geonczy, S. | N/A | Soil viral and prokaryotic communities shifted significantly after wildfire in chaparral and woodland habitats | |
| 氨氧化菌对深海无机碳固定的贡献 | Bayer, B. | N/A | Contribution of ammonia oxidizers to inorganic carbon fixation in the dark ocean | |
| 发酵白菜代谢组及其对Caco-2单层细胞因诱导的肠道屏障破坏的保护作用 | Marco, M. L. | N/A | The fermented cabbage metabolome and its protection against cytokine-induced intestinal barrier disruption of Caco-2 monolayers | |
| 钙调蛋白在Kv7.2通道钙响应域的共翻译折叠过程中充当伴侣蛋白。 | Muguruza-Montero, A. | N/A | Calmodulin acts as a chaperone during co-translational folding of the Kv7.2 channel Calcium Responsive Domain. | |
| 利托那韦从HIV-1蛋白酶解离的途径特异性解离自由能分布图 | Vig, E. | N/A | Pathway Specific Unbinding Free Energy Profiles of Ritonavir Dissociation From HIV-1 Protease | |
| N-甲酰犬尿氨酸，而非犬尿氨酸，进入免疫调节犬尿氨酸途径中的亲核试剂清除分支。 | Wang, Y. | N/A | N-formylkynurenine but not kynurenine enters a nucleophile-scavenging branch of the immune-regulatory kynurenine pathway | |
| 通过隐秘的青霉素结合蛋白型硫酯酶实现的生物催化四肽大环化 | Jeannette, P. L. | N/A | Biocatalytic Tetrapeptide Macrocyclization by Cryptic Penicillin-binding Protein-type Thioesterases | |
| 基于CRISPR的谱系追踪数据快速准确重建细胞谱系树的动态规划算法 | Dai, J. | N/A | Dynamic programming algorithms for fast and accurate cell lineage tree reconstruction from CRISPR-based lineage tracing data | |
| 核小体凝聚物和连接DNA改变了染色质折叠的路径和速率 | Qiu, Y. | N/A | Nucleosome condensate and linker DNA alter chromatin folding pathways and rates | |
| 多样化的群体感应系统调控着深海冷泉中微生物的交流和生物地球化学过程。 | Peng, J. | N/A | Diverse quorum sensing systems regulate microbial communication and biogeochemical processes in deep-sea cold seeps | |
| # BioRxiv 2024-11-15 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| MIRAGE：一种结合变异功能信息的贝叶斯稀有变异关联分析方法 | Han, S. | N/A | MIRAGE: a Bayesian rare variant association analysis method incorporating functional information of variants | |
| UFMTrack：下流迁移追踪器，能够在微流控设备中对跨越血脑屏障的整个多步骤免疫细胞渗出级联进行分析 | Vladymyrov, M. | N/A | UFMTrack: Under-Flow Migration Tracker enabling analysis of the entire multi-step immune cell extravasation cascade across the blood-brain barrier in microfluidic devices | |
| 基因组大小进化与毒蛙科（Dendrobatidae）的表型关联 | Douglas, T. E. | N/A | Genome size evolution and phenotypic correlates in the poison frog family Dendrobatidae | |
| 古代和现代伊比利亚牛中野牛杂交的基因组遗产 | Günther, T. | N/A | The Genomic Legacy of Aurochs hybridization in ancient and modern Iberian Cattle | |
| 人类额叶皮层的刺激表征支持工作记忆中的灵活控制 | Shao, Z. | N/A | Stimulus representation in human frontal cortex supports flexible control in working memory | |
| 鞘脂调控的突触核蛋白-1包涵体的成熟与解毒作用 | Cao, X. | N/A | Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids | |
| 复杂性状的普遍多基因性会夸大转录组全关联研究中的假阳性率 | Liang, Y. | N/A | Pervasive polygenicity of complex traits inflates false positive rates in transcriptome-wide association studies | |
| 行为药理学预测阿尔茨海默病风险基因斑马鱼突变体中的信号通路紊乱及候选治疗药物 | Kroll, F. | N/A | Behavioural pharmacology predicts disrupted signalling pathways and candidate therapeutics from zebrafish mutants of Alzheimer's disease risk genes | |
| 焦点粘附内整合素纳米簇的空间差异调控与激活 | Keary, S. | N/A | Differential spatial regulation and activation of integrin nanoclusters inside focal adhesions | |
| TIPPo：一种用户友好的工具，用于利用HiFi数据从头组装细胞器基因组 | Xian, W. | N/A | TIPPo: A User-Friendly Tool for De Novo Assembly of Organellar Genomes with HiFi Data | |
| 环境和种内及种间相互作用都会影响海洋捕食者的移动。 | Mourier, J. | N/A | Both environmental conditions and intra- and interspecific interactions influence the movements of a marine predator | |
| 所有细菌基因组 - 已组装、可用且可搜索的所有细菌基因组 | Hunt, M. | N/A | AllTheBacteria - all bacterial genomes assembled, available and searchable | |
| 一刀切不可取：确定远程相机陷阱实际视野范围的新方法 | Carswell, B. M. | N/A | One size does not fit all: a novel approach for determining the Realised Viewshed Size for remote camera traps | |
| 协调印度各地的树木库存数据集可以填补热带生态学中的关键空白。 | Anujan, K. | N/A | Harmonising distributed tree inventory datasets across India can fill critical gaps in tropical ecology | |
| 基于深度学习的细胞骨架分割技术，用于精确高效地测量细胞骨架密度 | Horiuchi, R. | N/A | Deep learning-based cytoskeleton segmentation for accurate high-throughput measurement of cytoskeleton density | |
| 使用Zarr进行生物银行规模分析就绪的VCF | Czech, E. A. | N/A | Analysis-ready VCF at Biobank scale using Zarr | |
| 紧密匹配的比较表明，可分离的过程介导了上下文大小错觉。 | Schwarzkopf, D. S. | N/A | Closely matched comparisons suggest that separable processes mediate contextual size illusions | |
| 一个低活动性的皮层网络专门编码句法 | Morgan, A. M. | N/A | A low-activity cortical network selectively encodes syntax | |
| 视觉隐性学习中的结构转移与巩固 | Garber, D. | N/A | Structure transfer and consolidation in visual implicit learning | |
| 结合AI与MD模拟，发现猴痘病毒H3中的硫酸乙酰肝素结合域作为抗痘病毒药物靶点 | Zheng, B. | N/A | Discovery of a Heparan Sulfate Binding Domain in Monkeypox Virus H3 as an Anti-poxviral Drug Target Combing AI and MD Simulations | |
| 新热带生物多样性指标的基因组学：两种蝴蝶辐射，伴随着广泛的染色体重排和杂交 | van der Heijden, E. S. | N/A | Genomics of Neotropical biodiversity indicators: two butterfly radiations with rampant chromosomal rearrangements and hybridisation | |
| 共享环境使得利用菌株解析的宏基因组学来推断微生物群落传播变得复杂。 | Debray, R. | N/A | Shared environments complicate the use of strain-resolved metagenomics to infer microbiome transmission | |
| HSPA2在卵裂球中的不对称表达决定了胚胎的第一次细胞命运决定。 | Gao, J. | N/A | The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision | |
| 小脑浦肯野细胞直接输出到脑干的特征 | Chen, C. H. | N/A | Characterization of direct Purkinje cell outputs to the brainstem | |
| 数据引导的人类成纤维细胞直接重编程为造血谱系 | Stansbury, C. | N/A | Data-guided direct reprogramming of human fibroblasts into the hematopoietic lineage | |
| 是的，它们都是独立的个体：用于重复调查数据的层次模型能够改进对树木生长和尺寸的估计。 | O'Brien, T. | N/A | Yes, they're all individuals: Hierarchical models for repeat survey data improve estimates of tree growth and size | |
| 细胞-细胞外基质（ECM）粘附的局部减弱通过细胞形态、肌动蛋白-肌球蛋白组织和E-钙粘蛋白水平的变化，触发了基底组织的折叠。 | Valencia-Exposito, A. | N/A | Local weakening of cell-ECM adhesion triggers basal tissue folding via changes in cell shape, actomyosin organization and E-cad levels | |
| 饮食诱导的肥胖中，时间限制性进食对小胶质细胞代谢的改善有限 | Jiao, H. | N/A | Limited microglial metabolic improvement with time-restricted feeding in diet-induced obesity | |
| 抑制去泛素化酶活性和炎症信号传导的分子胶 | Chandler, F. | N/A | Molecular glues that inhibit deubiquitylase activity and inflammatory signalling | |
| 质子化/去质子化驱动的低电位铁氧还蛋白氧化还原稳定性开关 | Wada, K. | N/A | Protonation/deprotonation-driven switch for the redox stability of low-potential ferredoxin | |
| 单细胞微藻生命周期中r策略与K策略的转变 | Liu, L. | N/A | A shift between r and K strategies in the life cycle of a unicellular microalga | |
| 相机陷阱无法确定橡皮泥制作的毛毛虫模型是否能可靠地测量鸟类捕食情况。 | SCHILLE, L. | N/A | Camera traps unable to determine whether plasticine models of caterpillars reliably measure bird predation | |
| 脂滴靶向ABHD5和PNPLA3 I148M是促进肝脏脂肪变性所必需的 | Teskey, G. | N/A | Lipid Droplet Targeting of ABHD5 and PNPLA3 I148M is required to promote liver steatosis | |
| 光化学分析突触和突触外NMDA受体分子多样性 | Sicard, A. | N/A | Optochemical profiling of NMDA receptor molecular diversity at synaptic and extrasynaptic sites | |
| 贫血和组织缺氧是疟疾低乳酸血症的主要决定因素。 | Georgiadou, A. | N/A | Anemia and tissue hypoxia are major determinants of malarial hypelactatemia | |
| 撤回：MIRAGE：一种结合变异功能信息的贝叶斯稀有变异关联分析方法 | Han, S. | N/A | WITHDRAWN: MIRAGE: a Bayesian rare variant association analysis method incorporating functional information of variants | |
| NACHO介导的五聚配体门控离子通道组装机制 | Hooda, Y. | N/A | Mechanism of NACHO-mediated assembly of pentameric ligand-gated ion channels | |
| 从单个词汇到句子生成：共享的皮层表征，但时间动态不同 | Morgan, A. M. | N/A | From single words to sentence production: Shared cortical representations but distinct temporal dynamics | |
| 光流解析作为因果源分离：一种从光流中并行提取物体和自运动信息的计算模型 | Scherff, M. | N/A | Flow parsing as causal source separation: A computational model for concurrent retrieval of object and self-motion information from optic flow | |
| 多维社会关系塑造了猴子的社会关注 | Liu, S. | N/A | Multi-dimensional social relationships shape social attention in monkeys | |
| QT-WEAVER：纠正四重分布尽管基因树估计错误，仍能提高系统基因组学分析 | Hasan, N. B. | N/A | QT-WEAVER: Correcting quartet distribution improves phylogenomic analyses despite gene tree estimation error | |
| 杨树：一种系统发育分析流程 | Koning, E. | N/A | Poplar: A Phylogenetics Pipeline | |
| 影响贝宁北部被忽视和未充分利用物种消费趋势的食品环境因素 | BANKOLE, B. M. V. | N/A | Food environment components influencing consumption trends of neglected and underutilized species in northern Benin | |
| 长春新碱治疗逆转局灶节段性肾小球硬化中的足细胞损伤 | Mason, W. J. | N/A | Vincristine treatment reverses podocyte damage in focal segmental glomerulosclerosis | |
| 确认气候变化对生物多样性的影响：全球调查结果 | Alshehab, E. A. | N/A | Confirming the Impact of Climate Change on Biodiversity: Results from a Global Survey | |
| AGAPE（计算G四链体亲和力预测）：首个用于G四链体结合亲和力预测的AI体内工作流程。 | D'Anna, L. | N/A | AGAPE (computAtional G-quadruplex Affinitiy PrEdiction): The first AI In-silico workflow for G-quadruplex binding affinity prediction. | |
| CPSM：用于预测单个癌症患者生存概率的自动化机器学习管道的R包 | Kaur, H. T. | N/A | CPSM: R-package of an Automated Machine Learning Pipeline for Predicting the Survival Probability of Single Cancer Patient | |
| 分层糖酵解途径调控人类肠道拟杆菌中碳水化合物利用调节因子 | Kabonick, S. G. | N/A | Hierarchical glycolytic pathways control the carbohydrate utilization regulator in human gut Bacteroides | |
| ABA通过提高苹果根系中的脂肪酸水平，促进丛枝菌根真菌的定殖。 | Jing, S. | N/A | ABA increases fatty acids levels in apple roots to boost colonization by arbuscular mycorrhizal fungi | |
| 非模式纤毛虫奇洛顿内拉·翁西纳塔（Chilodonella uncinata）的基因组内容：对其核结构、发育过程中体细胞大核内总DNA中基因大小染色体的见解 | Ahsan, R. | N/A | Genome content in the non-model ciliate Chilodonella uncinata: insights into nuclear architecture, gene-sized chromosomes among the total DNA in their somatic macronuclei during their development | |
| 在典型的“活化石”谱系中，表型进化的变异模式 | Rivero-Vega, R. A. | N/A | Variable patterns of phenotypic evolution among canonical 'living fossil' lineages | |
| 靶向降解易凝结的内源蛋白质可提高作物性能 | Xu, G. | N/A | Targeted degradation of endogenous condensation-prone proteins improves crop performance | |
| 叶面积大小决定了玉米在受损和植食性昆虫诱导下挥发性物质的释放量。 | Waterman, J. M. | N/A | Leaf size determines damage- and herbivore-induced volatile emissions in maize | |
| 大海捞针：从植物根部培养对植物有益的柔膜菌目菌株 | Bruyant, P. | N/A | Needle in a haystack: culturing plant-beneficial Helotiales lineages from plant roots | |
| 野猪源微生物移植对仔猪微生物群、代谢物谱及肠道促炎细胞因子产生的影响与母猪源微生物移植不同。 | Willing, B. P. | N/A | The impact of wild-boar derived microbiota transplantation on piglet microbiota, metabolite profile and gut proinflammatory cytokine production differs from sow-derived microbiota | |
| 从初始多能性到人类神经类器官：通过三维形态发生连续体 | Laterza, C. | N/A | From naïve pluripotency to human neural organoids through a three-dimensional morphogenetic continuum | |
| 特瓦坎谷的种子传播效果及植物-鸟类相互作用网络 | Contreras-Gonzalez, A. M. | N/A | Seed dispersal effectiveness and plant-bird interaction networks in the Tehuacan Valley | |
| 地中海植物物种与食草性节肢动物的关联及其对有机葡萄园中害虫数量的影响 | Santos, R. | N/A | The association of Mediterranean plant species with herbivorous arthropods and its effect on pest abundance in organic vineyards | |
| 通过结构建模和分化时间估算，理解植物和真菌病毒中RNA聚合酶的进化和功能关系 | Gracy, J. | N/A | Understanding evolutionary and functional relationships of RNA polymerases in plant and fungal viruses through structural modeling and divergence date estimations | |
| 斑胸草雀对鸣叫类型的分类和语义感知 | Elie, J. E. | N/A | Categorical and semantic perception of the meaning of call-types in zebra finches | |
| 玩还是不玩？玩伴熟悉度和社会隔离对三种实验室大鼠社交玩耍参与度的影响 | Orsucci, I. C. | N/A | To Play or Not to Play? Effects of Playmate Familiarity and Social Isolation on Social Play Engagement in Three Laboratory Rat Strains | |
| 光捕获复合物II通过脂质再分配抵抗植物类囊体膜中非双层脂质诱导的多态性 | Garg, A. | N/A | Light Harvesting Complex II Resists Non-Bilayer Lipid-Induced Polymorphism in Plant Thylakoid Membranes via Lipid Redistribution | |
| 双子叶植物茎对低红光：远红光的响应中的皮层细胞反应 | Li, L. | N/A | Pith cell responses to low red: far-red light in dicot stems | |
| 植物原生质体的动态皮层行为揭示了植物和动物细胞之间意想不到的相似性 | Dickmann, J. E. M. | N/A | Dynamic cortical behavior of plant protoplasts reveals unexpected similarities between plant and animal cells | |
| 拟南芥I类成形蛋白AtFH5有助于幼苗抵抗盐胁迫。 | Kollarova, E. | N/A | The Arabidopsis Class I formin AtFH5 contributes to seedling resistance to salt stress. | |
| 高可塑性增加了表型与环境的错配，导致未充分利用的作物物种表现不佳。 | Alagarasan, G. | N/A | High plasticity increases phenotype-environment mismatch leading to sub-optimal performance in underutilized crop species | |
| 寡聚半乳糖醛酸，由甜菜副产品的酶促降解产生，对小麦白粉病具有部分保护作用。 | Carton, C. | N/A | Oligogalacturonides, produced by enzymatic degradation of sugar beet by-products, confer partial protection against wheat powdery mildew | |
| 大豆胞囊线虫抗性蛋白AATRhg1影响氨基酸稳态和甜菜色素积累 | Du, Y. | N/A | Soybean Cyst Nematode-Resistant Protein AATRhg1 Affects Amino Acid Homeostasis and Betalain Accumulation | |
| 内生蚯蚓提取物对“促植物生长真菌”的影响 | Yakkou, L. | N/A | Effect of endogenous earthworm's extracts on "plant growth-promoting fungi" | |
| 晚分生组织身份2调控种子表面的角质层形成，并影响种子的寿命。 | Oshima, Y. | N/A | LATE MERISTEM IDENTITY2 regulates cuticle formation on the seed surface and influences seed longevity | |
| 光系统II组装因子RBD1和HCF136的拮抗作用是植物叶绿体中光调控psbA翻译的基础 | Rojas, M. | N/A | Opposing action of photosystem II assembly factors RBD1 and HCF136 underlies light-regulated psbA translation in plant chloroplasts | |
| 半冬性甘蓝型油菜品种中双11中FLOWERING LOCUS T相关基因的特征及其潜在的基因调控网络 | Wang, J. K. | N/A | Characterization of FLOWERING LOCUS T related genes and their putative gene regulatory network in semi-winter Brassica napus cultivar Zhongshaung11 | |
| 在黑暗条件下，早期幼苗的发育直接受到质体通过GUN1依赖性质体逆行途径的调控。 | Sajib, S. A. | N/A | Early seedling development in dark conditions is directly controlled by plastids through the GUN1-dependent plastid retrograde pathway | |
| 通过机器学习解密植物复杂的表现型特征 | Zdrazil, J. | N/A | Decrypting the complex phenotyping traits of plants by machine learning | |
| 乳酸片球菌在酸性胁迫下形态变化的计算分析 | Venugopal, A. | N/A | Computational analysis of morphological changes in Lactiplantibacillus plantarum under acidic stress | |
| UCE系统发育基因组学揭示了收获蚁属（Pogonomyrmex）的系统分类学和地理分布范围的演化 | Graber, L. C. | N/A | UCE phylogenomics inform the systematics and geographic range evolution of the harvester ant genus Pogonomyrmex | |
| 复合序列基序的信息论：复杂分子识别的突变和生物物理决定因素 | Mascolo, E. | N/A | Information Theory of Composite Sequence Motifs: Mutational and Biophysical Determinants of Complex Molecular Recognition | |
| 植物类囊体膜边缘区域的脂质多态性 | Böde, K. | N/A | Lipid polymorphism of the marginal region of plant thylakoid membranes | |
| SSNA1自组装及其微管结合在中心粒维持中的结构洞察 | Agostini, L. | N/A | Structural insights into SSNA1 self-assembly and its microtubule binding for centriole maintenance | |
| 脂质翻转酶ATP9A和ATP9B形成复合体，并参与从高尔基体到分泌途径的贡献。 | Yagi, T. | N/A | Lipid flippases ATP9A and ATP9B form a complex and contribute to the secretory pathway from the Golgi apparatus | |
| Smc5/6与微管的结合调控着动态的着丝粒周围染色质折叠 | Carre-Simon, A. | N/A | Smc5/6 association with microtubules controls dynamic pericentromeric chromatin folding | |
| 上游开放阅读框在果蝇进化和发育过程中缓冲翻译变异性 | Sun, Y. | N/A | Upstream open reading frames buffer translational variability during Drosophila evolution and development | |
| 昆虫在CENP-T蛋白家族中进化出了单体组蛋白折叠结构域 | Sankaranarayanan, S. R. | N/A | Insects evolved a monomeric histone-fold domain in the CENP-T protein family | |
| 一种新型秀丽隐杆线虫Tau扩散模型揭示了内溶酶体完整性和种子Tau聚集的关键基因 | Sandhof, C. A. | N/A | A Novel C. elegans Model for Tau spreading Reveals Genes Critical for Endolysosomal Integrity and Seeded Tau Aggregation | |
| Pin4 链接：酵母中葡萄糖饥饿后的转录后和转录反应 | Ristova, M. | N/A | Pin4 Links Post-transcriptional and Transcriptional Responses to Glucose Starvation in Yeast | |
| 跨物种类器官揭示了多巴胺能神经元发育和脆弱性的人类特异性分子特征 | Nolbrant, S. | N/A | Interspecies Organoids Reveal Human-Specific Molecular Features of Dopaminergic Neuron Development and Vulnerability | |
| 妊娠期长度驱动有胎盘哺乳动物的大脑尺寸和胎仔数量变化 | Danis, T. | N/A | Gestation length drives brain size and litter size variation in eutherian mammals | |
| AI辅助成像筛查揭示了机械分子组织者和信号枢纽网络。 | Bertocchi, C. | N/A | AI-assisted imaging screening reveals mechano-molecular tissue organizers and network of signaling hubs. | |
| TopLib：构建和搜索自上而下的质谱库，用于蛋白质变体鉴定 | Li, K. | N/A | TopLib: Building and searching top-down mass spectral libraries for proteoform identification | |
| iModMix：多组学数据的综合模块分析 | Narvaez-Bandera, I. Y. | N/A | iModMix: Integrative Module Analysis for Multi-omics Data | |
| VIRALpre：融合K-mer特征的病毒基因组基础模型嵌入用于病毒识别 | Wang, Z. | N/A | VIRALpre: Genomic Foundation Model Embedding Fused withK-mer Feature for Virus Identification | |
| AlphaRING：通过蛋白质建模和残基相互作用网络分析进行错义变异分类 | Logsdon, A. | N/A | AlphaRING: Missense Variant Classification via Protein Modelling and Residue Interaction Network Analysis | |
| 利用基因表达数据预测多发性骨髓瘤分期和MGUS进展的机器学习模型 | Karathanasis, N. | N/A | Machine Learning Models for Predicting Multiple Myeloma Staging and MGUS Progression Using Gene Expression Data | |
| 肌球蛋白II细丝结构特性对力生成的影响 | Ding, S. | N/A | Impacts of Structural Properties of Myosin II Filaments on Force Generation | |
| 在乳腺癌中，维持CDK4/6抑制剂并结合CDK2抑制剂超越进展的治疗益处 | Armand, J. | N/A | Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer | |
| 昼夜节律基因Dec2通过调控肿瘤细胞抗原呈递促进免疫逃逸，从而促进胰腺癌休眠。 | Harris, C. R. | N/A | The circadian gene Dec2 promotes pancreatic cancer dormancy by regulating tumor cell antigen presentation to facilitate immune evasion | |
| 啮齿动物的垂直袖状胃切除术：对母亲代谢、心血管和肝脏功能的影响及围产期后果 | Payen, C. | N/A | Vertical sleeve gastrectomy in rodents: impact on metabolic, cardiovascular and hepatic functions of mothers and perinatal consequences | |
| 需要能力建设以充分利用获取生物多样性收藏的益处 | Groom, Q. | N/A | Capacity building needed to reap the benefits of access to biodiversity collections | |
| T细胞介导的克罗恩病上皮完整性损害 | Hamoudi, S. | N/A | T cell mediated impairment of epithelial integrity in Crohn's disease | |
| 慢性炎症驱动附睾三级淋巴结构形成和自身免疫性生育障碍 | Elizagaray, M. L. | N/A | Chronic inflammation drives epididymal tertiary lymphoid structure formation and autoimmune fertility disorders | |
| ENTPD3特异性CAR调节性T细胞用于T1D的局部免疫控制 | Pieper, T. | N/A | ENTPD3-specific CAR Regulatory T cells for Local Immune Control in T1D | |
| AIP56是由杀鱼气单胞菌（Photobacterium damselae subsp. piscicida）分泌的一种AB毒素，它对髓系细胞具有趋向性。 | Freitas, I. L. | N/A | AIP56, an AB toxin secreted by Photobacterium damselae subsp. piscicida, has tropism for myeloid cells | |
| LTB4通过一种受体转激活机制被转化为一种强效的人类中性粒细胞NADPH氧化酶激活剂，其中BLT1受体激活游离脂肪酸受体2。 | Wu, Y. | N/A | LTB4 is converted into a potent human neutrophil NADPH oxidase activator via a receptor transactivation mechanism in which the BLT1 receptor activates the free fatty acid receptor 2 | |
| 计算机生物群落区划方法 | Sukhanov, V. | N/A | Computer method of biocenotic zoning | |
| 火灾后的幼苗更新：解开微生境条件和种子可获得性的作用 | Beck, J. J. | N/A | Seedling recruitment after fire: Disentangling the roles of microsite conditions and seed availability | |
| 填补基因组空白：草类作物进化中的泛草类同源基因集 | Dias, H. M. | N/A | Bridging Genomic Gaps: The Pan-Grass Syntenic Gene Set in Grass Crop Evolution | |
| DreaM：一种用于增强重复基因组区域短读序列分析的计算流程 | Kumar, S. | N/A | DreaM: A Computational Pipeline for Enhanced Short-Read Sequence Analysis in Repetitive Genomic Regions | |
| 揭示与乳腺癌发展相关的表观遗传调控元件 | Jardanowska-Kotuniak, M. | N/A | Unveiling epigenetic regulatory elements associated with breast cancer development | |
| 通过大量和单细胞RNA测序揭示的诺林在神经视网膜分化中的潜在作用 | Maggi, K. | N/A | Putative Role of Norrin in Neuroretinal Differentiation Revealed by bulk and scRNA Sequencing of Human Retinal Organoids | |
| 在纳米尺度上，左旋多巴与脑部疾病蛋白质的相互作用 | Bergaglio, T. | N/A | On Levodopa interactions with brain disease proteins at the nanoscale | |
| 人类肠神经胶质在急性脑损伤临床前模型中的再生潜力 | Colitti, N. | N/A | Regenerative potential of human enteric glia in a preclinical model of acute brain injury | |
| 盲点填补是多感官的 | Chan, A. | N/A | Filling-in of the Blindspot is Multisensory | |
| 人脑中的区域脑熵、脑网络及结构-功能耦合 | Song, D. | N/A | Regional Brain Entropy, Brain Network and Structural-Functional Coupling in Human Brain | |
| 用于与神经退行性疾病研究界共享的额颞叶痴呆单MAPT敲入小鼠模型 | Morito, T. | N/A | Single MAPT knock-in mouse models of frontotemporal dementia for sharing with the neurodegenerative research community | |
| 急性低氧性缺氧对大脑血流反应性的变异性 | Johnson, H. R. | N/A | Variable Cerebral Blood Flow Responsiveness to Acute Hypoxic Hypoxia | |
| 睡眠剥夺后的注意力失误代表了脑脊液流动的瞬间。 | Yang, Z. | N/A | Attentional failures after sleep deprivation represent moments of cerebrospinal fluid flow | |
| 单细胞分析显示，单核细胞基因表达谱影响急性治疗队列中HIV-1储库的大小 | Ehrenberg, P. K. | N/A | Single-cell analyses reveal that monocyte gene expression profiles influence HIV-1 reservoir size in acutely treated cohorts | |
| 一种与侧位、心脏和肾脏缺陷相关的人类WNT11功能丧失型纯合变异 | Berns, H. E. | N/A | A homozygous human WNT11 loss-of-function variant associated with laterality, heart and renal defects | |
| 骨形态发生蛋白信号通路与乙醇相互作用破坏了腭的形成，与gata3无关 | Lovely, C. B. | N/A | Bone Morphogenetic Protein signaling pathway - ethanol interactions disrupt palate formation independent of gata3 | |
| 城市绿地连通性促使宿主群落变化及蜱传病原体感染转变 | VanAcker, M. C. | N/A | Urban greenspace connectivity drive shifts in host assemblages and tick-borne pathogen infection | |
| 将机器学习与流式成像显微技术相结合，实现藻华的自动化监测 | Khan, F. | N/A | Integrating Machine Learning with Flow-Imaging Microscopy for Automated Monitoring of Algal Blooms | |
| 长读测序揭示了在无脊椎动物-脊椎动物过渡阶段，细胞间信号传导的关键转录因子效应物中同工型多样性的增加 | Torres-Aguila, N. P. | N/A | Long-Read Sequencing Reveals Increased Isoform Diversity in Key Transcription Factor Effectors of Intercellular Signalling at the Invertebrate-Vertebrate Transition | |
| 增强GPT模型在基因组学分析中的应用：通过RAG和微调生成可信的遗传变异注释与解读 | Lu, S. | N/A | Boosting GPT Models for Genomics Analysis: Generating Trusted Genetic Variant Annotations and Interpretations through RAG and fine-tuning | |
| 组织微环境中的破坏性变化在肺癌发生不同阶段促进了致癌过程的启动。 | Venkat, V. | N/A | Disruptive changes in tissue microenvironment prime oncogenic processes at different stages of carcinogenesis in lung | |
| 体积和扩散张量成像生物标志物表明，在轻度创伤性脑损伤的青年猪模型中，存在长期持续的脑震荡后异常。 | Islam, S. | N/A | Volumetric and Diffusion Tensor Imaging biomarkers indicating long lasting post-concussion abnormalities in a youth pig model of mild Traumatic Brain Injury | |
| 多级混合制备核壳结构显著提升载DNA脂质纳米粒的转染效率，提升幅度达数量级。 | Nong, J. | N/A | Multi-stage-mixing to create a core-then-shell structure improves DNA-loaded lipid nanoparticles transfection by orders of magnitude | |
| 通过多重电化学实时局部炎症追踪一氧化氮传感器（MERLIN）进行伤口状态监测 | Wang, L. | N/A | Wound state monitoring by multiplexed, electrochemical, real-time, localized, inflammation-tracking nitric oxide sensor (MERLIN) | |
| HSPB5中的蛋白稳态相关变异破坏了αB-晶体蛋白结构域的稳定性 | Khatun, M. S. | N/A | Proteostasis Associated Variants in HSPB5 Destabilize the αB-crystallin Domain | |
| 使用MMseqs2进行GPU加速的同源搜索 | Kallenborn, F. | N/A | GPU-accelerated homology search with MMseqs2 | |
| 使用参数高效的迁移学习进行免疫蛋白的精确结构预测 | Zhu, T. | N/A | Accurate structure prediction of immune proteins using parameter-efficient transfer learning | |
| 用于芽殖酵母无标记基因编辑的自动化质粒设计 | Stojkovic, L. | N/A | Automated plasmid design for marker-free genome editing in budding yeast | |
| scMoE：通过稀疏专家混合实现单细胞多模态多任务学习 | Yun, S. | N/A | scMoE: single-cell Multi-Modal Multi-Task Learning via Sparse Mixture-of-Experts | |
| 人类5' UTR序列的多目标计算优化 | Yamada, K. | N/A | Multi-objective computational optimization of human 5' UTR sequences | |
| scTrace+：通过整合谱系追踪和多方面的转录组相似性信息来增强细胞命运推断 | Guo, W. | N/A | scTrace+: enhance the cell fate inference by integrating the lineage-tracing and multi-faceted transcriptomic similarity information | |
| 中期染色单体表面凝聚的核内分区 | Murugesan, V. | N/A | Nuclear partitioning by surface condensation on metaphase chromatids | |
| 评估NF1突变肿瘤细胞中治疗性自噬抑制的效果 | Zahedi, S. | N/A | The assessment of therapeutic autophagy inhibition in NF1 mutated tumor cells | |
| 针对SLC7A11介导的半胱氨酸代谢治疗曲妥珠单抗耐药的HER2阳性乳腺癌 | Hua, Y. | N/A | Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab resistant HER2 positive breast cancer | |
| 精子甲基组对衰老和应激反应的分子基础 | Arowolo, O. | N/A | Molecular Basis of Sperm Methylome Response to Aging and Stress | |
| 视觉系统中正向和反向α波段传播波的分层多尺度模型 | Schwenk, J. C. B. | N/A | A hierarchical multiscale model of forward and backward alpha-band traveling waves in the visual system | |
| 高分辨率成像图谱揭示了胰腺交感神经支配在糖尿病小鼠中的情境依赖性作用 | Xu, Q. | N/A | High-resolution imaging atlas reveals context-dependent role of pancreatic sympathetic innervation in diabetic mice | |
| 国际多队列分析揭示了量化重症疾病中免疫失调的新框架：SUBSPACE联盟研究结果 | Moore, A. R. | N/A | International multi-cohort analysis identifies novel framework for quantifying immune dysregulation in critical illness: results of the SUBSPACE consortium | |
| 肺泡巨噬细胞在纳米颗粒吸入过程中启动空间定向的中性粒细胞招募 | Liu, Q. | N/A | Alveolar macrophages initiate the spatially targeted neutrophil recruitment during nanoparticle inhalation | |
| 年老的秀丽隐杆线虫（Caenorhabditis elegans）的抗病毒防御能力下降，这是由于DRH-1/RIG-I的去SUMO化作用通过ULP-4/SENP7的丧失所导致的。 | Zhang, Y. | N/A | Antiviral defense in aged Caenorhabditis elegans declines due to loss of DRH-1/RIG-I deSUMOylation via ULP-4/SENP7 | |
| 通过近红外光谱和云端神经网络实现生物制剂的快速原位检测 | Leseigneur, C. | N/A | Rapid and In-situ Detection of Biological Agents via Near-Infrared Spectroscopy and Cloud-Powered Neural Networks | |
| 一项针对肝脏染色体结构的全基因组图谱研究表明，性别决定了饮食诱导的核小体动力学。 | ZHANG, Z. | N/A | A genome-wide ATLAS of liver chromatin architecture reveals that sex dictates diet-induced nucleosome dynamics | |
| 自发性高血压易卒中大鼠尿液蛋白质组特征分析 | Meng, W. | N/A | Urinary Proteome Characterization of Stroke-Prone Spontaneously Hypertensive Rats | |
| 土耳其商业一品红中相关桃树植原体候选菌株的出现 | Benlioglu, K. | N/A | Occurrence of a Candidatus Phytoplasma pruni Related Strain Associated with Commercial Poinsettias in Turkey | |
| 元基因组学洞察：氨回收生物反应器中参与N2O缓解和反硝化还原为氨的活性细菌 | Phan, H. V. | N/A | Meta-omic insights into active bacteria mediating N2O mitigation and dissimilatory nitrate reduction to ammonium in an ammonia recovery bioreactor | |
| 顺应潮流：利用礁石尺度的水动力学进行基于幼虫的恢复的规模扩大 | Gouezo, M. | N/A | Going with the flow: leveraging reef-scale hydrodynamics for upscaling larval-based restoration | |
| 蚊翅图像库：推进基于几何形态计量学和人工智能识别的研究 | Nolte, K. | N/A | Mosquito Wing Image Repository for Advancing Research on Geometric Morphometric- and AI-Based Identification | |
| 更新世海平面波动塑造了濒危的洛德豪岛蟑螂（Panesthia lata）在整个群岛范围内的种群结构。 | Adams, M. W. D. | N/A | Pleistocene sea-level fluctuation shapes archipelago-wide population structure in the Endangered Lord Howe Island cockroach Panesthia lata | |
| 首次为三种海葵（珊瑚纲：海葵目）宿主的克隆鱼物种生成了从头HiFi基因组组装 | De Jode, A. | N/A | The first de novo HiFi genome assemblies for three clownfish-hosting sea anemone species (Anthozoa: Actiniaria) | |
| 具有自体组织驻留巨噬细胞的人类心脏类器官再现了生理性的免疫-心脏相互作用 | O'Hern, C. | N/A | Human heart assembloids with autologous tissue-resident macrophages recreate physiological immuno-cardiac interactions | |
| 在临床质子治疗系统的同步回旋加速器室内，对A549肺癌细胞和IMR90健康人成纤维细胞进行体外FLASH辐照。 | Zazpe, A. | N/A | In vitro FLASH irradiation of A549 lung cancer cells and IMR90 healthy human fibroblasts in the synchrocyclotron room of a clinical proton therapy system | |
| 用于狨猴神经科学设备的开放获取资源 | Rollin, I. Z. | N/A | An Open Access Resource for Marmoset Neuroscientific Apparatus | |
| 使用CryFold改进冷冻电镜图的自动化模型构建 | Su, B. | N/A | Improved automated model building for cryo-EM maps using CryFold | |
| scCompass：一个集成的跨物种单细胞RNA测序数据库，为AI准备就绪 | Wang, P. | N/A | scCompass: An integrated cross-species scRNA-seq database for AI-ready | |
| 无膜细胞器的蛋白质稳态网络的组织 | Lim, C. M. | N/A | Organization of the Proteostasis Network of Membraneless Organelles | |
| 超快弹性毛细管风扇控制波纹虫和机器人的敏捷机动 | Ortega-Jimenez, V. | N/A | Ultrafast elastocapillary fans control agile maneuvering in ripple bugs and robots | |
| 动态捕获的凝聚融合创造出具有不同材料特性的复杂结构 | Erkamp, N. A. | N/A | Dynamically arrested condensate fusion creates complex structures with varying material properties | |
| 由雄激素受体转录激活域与小分子药物形成共价加合物后仍保持无序状态。 | Zhu, J. | N/A | Covalent adducts formed by the androgen receptor transactivation domain and small molecule drugs remain disordered | |
| 癌症相关突变对聚腺苷二磷酸核糖聚合酶1抑制作用的影响 | Shanmugam, N. | N/A | Impact of a Cancer-Associated Mutation on Poly(ADP-ribose) Polymerase1 Inhibition | |
| MR-ARFI在人体经颅聚焦超声中的优化 | Mohammadjavadi, M. | N/A | Optimization of MR-ARFI for Human Transcranial Focused Ultrasound | |
| 起源的基底细胞解决了癌症中神经内分泌-丛状谱系可塑性 | Ireland, A. S. | N/A | Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer | |
| 基于逻辑的机器学习预测艾司西酞普兰如何抑制心肌细胞肥大 | Eggertsen, T. G. | N/A | Logic-based machine learning predicts how escitalopram inhibits cardiomyocyte hypertrophy | |
| 无偏倚地发现能够刺激巨噬细胞介导的B细胞淋巴瘤破坏的抗体疗法 | Ribeiro, J. | N/A | Unbiased discovery of antibody therapies that stimulate macrophage-mediated destruction of B-cell lymphoma | |
| 酪蛋白2A2通过增强免疫突触内CD45磷酸酶活性促进T细胞免疫调节 | Ali, S. | N/A | Butyrophilin 2A2 promotes T cell immunoregulation by enhancing CD45 phosphatase activity within the immune synapse | |
| RecN和RecA在埃希氏大肠杆菌中协调了环丙沙星暴露后有序的DNA超压缩反应。 | Vikedal, K. | N/A | RecN and RecA orchestrate an ordered DNA supercompaction response following ciprofloxacin exposure in Escherichia coli | |
| 一种快速、经济高效的高产DNA从PCR产物和琼脂糖凝胶中纯化的方法。 | Fatima, S. | N/A | A Rapid, Cost-Effective Method for High-Yield DNA Purification from PCR Products and Agarose Gels. | |
| 解密金黄色葡萄球菌中含Com_YlbF结构域蛋白质的功能。 | Rozo, Z. L. C. | N/A | Deciphering the function of Com_YlbF domain-containing proteins in Staphylococcus aureus. | |
| Sla2 是网格蛋白轻链与 Pan1/End3/Sla1 复合体之间的核心相互作用枢纽。 | Draper-Barr, G. | N/A | Sla2 is a core interaction hub for Clathrin Light Chain and the Pan1/End3/Sla1Complex | |
| 急性呼吸窘迫综合征肺部细胞外基质的组成变化 | Fan, Y. | N/A | Compositional changes of the lung extracellular matrix in acute respiratory distress syndrome | |
| 将纳米孔MinION测序整合到国家动物健康抗菌素耐药性监测计划中：一项关于印尼鸡肉屠宰场废水和河流的试点研究 | Telussa, R. | N/A | Integrating Nanopore MinION Sequencing into National Animal Health AMR Surveillance Programs: An Indonesian Pilot Study of Chicken Slaughterhouse Effluent and Rivers | |
| 利用绿色和近红外荧光蛋白的荧光交叉相关光谱技术，在活细胞中定量测定细胞周期蛋白-CDK的解离常数。 | Toyama, A. | N/A | Quantification of Cyclin-CDK dissociation constants in living cells using fluorescence cross-correlation spectroscopy with green and near-infrared fluorescent proteins. | |
| 揭示珊瑚礁的普遍空间特性 | Gimenez-Romero, A. | N/A | Unravelling the universal spatial properties of coral reefs | |
| 在珊瑚Montipora capitata中，遮蔽不会降低其热耐受性：对保护干预的启示 | Ducret, H. | N/A | Shading does not lower thermal tolerance in the coral Montipora capitata: implications for conservation intervention | |
| 减去误差：在存在残留对齐错误的情况下估计dN/dS并测试自然选择 | Selberg, A. | N/A | Minus the Error: Estimating dN/dS and Testing for Natural Selection in the Presence of Residual Alignment Errors | |
| 蜥蜴和喙头蜥（鳞龙类）中松果体非视觉视蛋白的演化 | Romero, R. D. | N/A | Evolution of pineal non-visual opsins in lizards and the tuatara (Lepidosauria) | |
| 重新定义性传播寄生虫阴道毛滴虫及其在鸽形目鸟类中的近缘物种的剪接体内含子 | Callejas-Hernandez, F. | N/A | Redefining the spliceosomal introns of the sexually transmitted parasite Trichomonas vaginalis and its close relatives in columbid birds | |
| 使用Takoyaki超声技术对深层组织中的细胞和分子进行实时体积成像 | Lee, S. | N/A | Real-time volumetric imaging of cells and molecules in deep tissues with Takoyaki ultrasound | |
| 常见的AAV基因治疗载体表现出对活体人脑细胞类型的无差别转导 | McGinnis, J. | N/A | Common AAV gene therapy vectors show indiscriminate transduction of living human brain cell types | |
| 优化VSV G骨架以实现与纳米抗体的氨基端融合，使其能够重新定向至治疗相关受体的受体。 | Duquenois, I. | N/A | Optimization of the VSV G backbone for amino terminal fusion with nanobodies allowing its retargeting to receptors of therapeutic interest. | |
| 用于血友病B的通用碱基编辑 | Baatartsogt, N. | N/A | Universal base editing for hemophilia B | |
| 高适应度路径可以连接序列重叠度低的蛋白质 | Kantroo, P. | N/A | High fitness paths can connect proteins with low sequence overlap | |
| 从知识库、注册表和多组学数据生成生物医学知识图谱 | Qin, G. | N/A | Generating Biomedical Knowledge Graphs from Knowledge Bases, Registries, and Multiomic Data | |
| 在优化后的Colab处理器上对GROMACS进行基准测试，以及云计算在分子动力学中的灵活性 | Karagöl, T. | N/A | Benchmarking GROMACS on Optimized Colab Processors and the Flexibility of Cloud Computing for Molecular Dynamics | |
| DDA-BERT：利用基于数据依赖采集质谱的蛋白质组学中的Transformer架构预训练 | A, J. | N/A | DDA-BERT: leveraging transformer architecture pre-training for data-dependent acquisition mass spectrometry-based proteomics | |
| 用于预测病毒-人类蛋白质相互作用的机器学习方法：对逆转录病毒相互作用网络的评估 | Mahmoudi, O. | N/A | Machine Learning Approaches for Predicting Virus-Human Protein-Protein Interactions: An Evaluation of Retroviral Interaction Networks | |
| 一种用于从头设计抗菌肽的多属性优化生成对抗网络 | Liu, J. | N/A | A Multi-Property Optimizing Generative Adversarial Network for de novo Antimicrobial Peptide Design | |
| 使用PhenoGeneRanker识别与阿尔茨海默病相关的基因 | Rahman, M. T. | N/A | Identifying Alzheimer's disease-associated genes using PhenoGeneRanker | |
| 原子基本通量模式解释了大规模通量网络中代谢物的稳态流动 | Chitpin, J. G. | N/A | Atomic elementary flux modes explain the steady state flow of metabolites in large-scale flux networks | |
| 脂质包装缺陷是α-突触核蛋白膜结合的必要且充分条件 | Johnson, D. H. | N/A | Lipid Packing Defects are Necessary and Sufficient for Membrane Binding of alpha-Synuclein | |
| 人类线粒体复制解旋酶的实时动力学自动调节 | Plaza G-A, I. | N/A | Auto-regulation of the real-time kinetics of the human mitochondrial replicative helicase | |
| 通过不对称纳米孔解析电流整流 | Lin, Y. | N/A | Dissecting current rectification through asymmetric nanopores | |
| 利用染色质包装域在体内靶向化疗逃逸 | Frederick, J. | N/A | Leveraging chromatin packing domains to target chemoevasion in vivo | |
| 空间排斥抵消了ER到脂滴的蛋白质运动 | Damm, A. | N/A | Steric Repulsion Counteracts ER-to-Lipid Droplet Protein Movement | |
| 一个稳健的计算框架，用于优化CDK7抑制剂作为有前景的癌症疗法 | Shi, Z. | N/A | A Robust Computational Framework for the Optimization of CDK7 Inhibitors as Promising Cancer Therapy | |
| 糖皮质激素受体凝聚物在转录调控中的标志 | Benitez, B. | N/A | Hallmarks of glucocorticoid receptor condensates involvement in transcription regulation | |
| C1C2通道视紫红质开启机制的结构见解 | Mulder, M. | N/A | Structural insights into the opening mechanism of C1C2 channelrhodopsin | |
| 波形蛋白中的单一半胱氨酸残基通过调控长链非编码RNA XIST，抑制乳腺癌中的上皮-间质转化及干细胞特性 | Usman, S. | N/A | A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer | |
| 代谢重编程与染料木黄酮和化疗在人乳腺癌细胞中的协同细胞毒性 | Tobon-Cornejo, S. | N/A | Metabolic reprogramming and synergistic cytotoxicity of genistein and chemotherapy in human breast cancer cells | |
| 5q缺失型急性髓系白血病是一种表观遗传学上独特的亚群，其特征是KDM3B的杂合性缺失。 | Kelly, K. | N/A | Acute Myeloid Leukemia with deletion 5q is an epigenetically distinct subgroup defined by heterozygous loss of KDM3B | |
| 古生态系统的选择、演化和持久性 | Roopnarine, P. D. | N/A | Selection, Evolution and Persistence of Paleoecological Systems | |
| 表观遗传调节NLRP6炎症小体传感器作为一种治疗手段，以减少HIV/SIV感染中由坏死性凋亡驱动的胃肠道黏膜功能障碍 | Premadasa, L. S. | N/A | Epigenetic modulation of NLRP6 inflammasome sensor as a therapeutic modality to reduce necroptosis-driven gastrointestinal mucosal dysfunction in HIV/SIV infection | |
| 激素诱导的血栓形成是通过非经典的纤维蛋白（原）聚集和斑马鱼中一种新的雌激素靶点介导的。 | Yu, X. | N/A | Hormone-induced thrombosis is mediated through non-canonical fibrin(ogen) aggregation and a novel estrogen target in zebrafish | |
| 全动物表型药物筛选鉴定出抑制动脉粥样硬化脂蛋白的药物。 | Kelpsch, D. J. | N/A | A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins. | |
| 量化环境传播和年龄特异性易感性的关键参数，针对鸟分枝杆菌副结核亚种（MAP） | Gao, Y. | N/A | Quantifying Key Parameters of Environmental Transmission and Age-Specific Susceptibility for Mycobacterium avium subspecies paratuberculosis (MAP) | |
| 饮食限制增强CD8+ T细胞酮体代谢以限制衰竭并提升抗肿瘤免疫 | Oswald, B. M. | N/A | Dietary Restriction Enhances CD8+ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity | |
| 新发现的鼠CD103-树突状细胞是高度免疫活性的常规DC2亚群，与已知的鼠和人类树突状细胞亚群相对应。 | Sawanobori, Y. | N/A | Newly found rat CD103- dendritic cells are the highly immunogenic conventional DC2 subpopulation, corresponding to the known DC subsets in mice and humans. | |
| 伴随文章：《嗜酸性食管炎中牛奶过敏原免疫识别的分子基础》 | Dilollo, J. | N/A | Companion to: A molecular basis for milk allergen immune recognition in eosinophilic esophagitis | |
| 利用核糖体图谱技术揭示新型保守的HIV-1开放阅读框，编码T细胞抗原。 | Bertrand, L. | N/A | Unveiling novel conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling. | |
| 揭示流感A病毒中的重配现象：TreeSort的应用 | Markin, A. | N/A | Revealing reassortment in influenza A viruses with TreeSort | |
| 多层次的生态相互作用决定了临床耐药菌株在人类微生物群中的生长 | Leon-Sampedro, R. | N/A | Multi-layered ecological interactions determine growth of clinical antibiotic-resistant strains within human microbiomes | |
| 温度调节疟蚊共生体微孢子虫MB的传播潜力，该共生体可阻断疟疾传播 | Otieno, F. G. | N/A | Temperature modulates the dissemination potential of Microsporidia MB, a malaria-blocking endosymbiont of Anopheles mosquitoes | |
| 利用包膜二聚体开发蜱传脑炎病毒纳米颗粒疫苗 | Wang, B. | N/A | Development of a tick-borne encephalitis virus nanoparticle vaccine utilizing envelope dimer | |
| 促炎通路在小鼠模型中参与艰难梭菌感染的发病机制——一项空间转录组学研究 | Ghahari, N. | N/A | Pro-inflammatory Pathways Contribute to Pathogenesis of Clostridioides difficile Infection in a Murine Model - A Spatial Transcriptomics Study | |
| 探索人类TSG101的UEV结构域的药物潜力，以寻找广谱抗病毒药物 | Montero, F. | N/A | Exploring the druggability of the UEV domain of human TSG101 in search for broad-spectrum antivirals | |
| KPC-14的特性：一种KPC变异体，赋予广泛耐药的ST463铜绿假单胞菌临床分离株对头孢他啶-阿维巴坦的耐药性 | Xiao, Y. | N/A | Characteristic of KPC-14, a KPC Variant Conferring Resistance to Ceftazidime-Avibactam in the Extensively Drug-resistant ST463 Pseudomonas aeruginosa Clinical Isolate | |
| 通过基于原位荧光杂交的光学筛选鉴定ALT途径的新型调节因子 | Azeroglu, B. | N/A | Identification of Novel Modulators of the ALT Pathway Through a Native FISH-Based Optical Screen | |
| autoFISH - 一个用于连续单分子荧光原位杂交实验的模块化工具箱 | Weber, C. | N/A | autoFISH - a modular toolbox for sequential smFISH experiments | |
| 外泌体中miRNAs分选的负调控：RNA结合蛋白PCBP2损害SYNCRIP介导的miRNAs外泌体装载 | Marocco, F. | N/A | Negative regulation of miRNAs sorting in EVs: the RNA-binding protein PCBP2 impairs SYNCRIP-mediated miRNAs EVs loading | |
| 排斥性客户关机在Yb体内的短暂寄居在Piwi-piRISC生物发生和维持生育能力中起着关键作用。 | Hirakata, S. | N/A | Transient residence of the repulsive client Shutdown in Yb bodies plays a critical role in Piwi-piRISC biogenesis and maintaining fertility | |
| ATR保护复制叉免受APOBEC3B诱导的有害PARP1捕获的影响 | Ortega, P. | N/A | ATR safeguards replication forks against APOBEC3B-induced toxic PARP1 trapping | |
| 恢复PKM1通过调节PEP代谢改善人干细胞衍生的β细胞的功能成熟 | Lin, H. | N/A | Restoration of PKM1 improves functional maturation of human stem-cell derived-β cell by regulating PEP metabolism | |
| 顶复门DedA超家族蛋白VMP1对于分泌器官的生物发生和功能至关重要 | Reddy, G. S. | N/A | The apicomplexan DedA superfamily protein VMP1 is crucial for the biogenesis and function of secretory organelles | |
| Jagged1是一种在血管内皮细胞中独立于Notch的机械转导因子。 | Suarez Rodriguez, F. | N/A | Jagged1 is a Notch-independent mechanotransducer in endothelial cells | |
| 通过体表碳氢化合物识别合适交配伴侣——一种具有极端同性二态性的物种 | Moris, V. C. | N/A | Recognition of an appropriate mating partner using cuticular hydrocarbons in a species with an extreme intra-sexual dimorphism | |
| 吸引猎物但不被捕食者排斥表明在遭遇-躲避-逃脱序列中存在不对称的投资。 | Ferry, N. | N/A | Prey attracting but not repelled by predators suggests an asymmetric investment in the encounter-avoid-escape sequence. | |
| 从恐惧到盛宴：响尾蛇在恐惧的景观中导航以优化觅食 | Da Cunha, O. | N/A | FROM FEAR TO FEAST: RATTLESNAKES NAVIGATE THE LANDSCAPE OF FEAR TO OPTIMIZE FORAGING | |
| 恢复的生物标志物：生态修复后营养流动的特征化 | Spindel, N. B. | N/A | Biomarkers of recovery: characterizing trophic flow following ecological restoration | |
| 大象应该吃草还是吃树叶？杂食性巨型草食动物饮食变化的养分和功能后果 | Gautam, H. | N/A | Should elephants graze or browse? The nutritional and functional consequences of dietary variation in a mixed-feeding megaherbivore | |
| 来自较高羊膜动物的CGGBP1限制胞嘧啶甲基化，并在被抑制的启动子处驱动转录因子结合位点的GC偏向性 | Kumar, P. | N/A | CGGBP1 from higher amniotes restricts cytosine methylation and drives a GC-bias in transcription factor binding sites at repressed promoters | |
| 扩展的“共同原因”：间断进化与沉积过程之间的因果联系 | Polly, P. D. | N/A | The extended 'common cause': causal links between punctuated evolution and sedimentary processes | |
| 三刺鱼中的新生突变率 | Zhang, C. | N/A | Rate of de novo mutations in the three-spined stickleback | |
| 热带岛屿特有鸟类的种群数量对气候的响应受到栖息地可用性和物种特性的调节。 | Karjee, R. | N/A | Tropical island endemic birds' demographic responses to climate are modulated by habitat availability and species traits | |
| 通过连续不对称减数分裂实现的自我抑制性染色体驱动 | Meng, X. | N/A | Self-restrained sex chromosome drive through sequential asymmetric meiosis | |
| 结合功能注释和多性状精细定位方法可提高血糖性状位点的精细定位分辨率 | Soenksen, J. | N/A | Combining functional annotation and multi-trait fine-mapping methods improves fine-mapping resolution at glycaemic trait loci | |
| 在生物实验中使用逻辑回归和Cochran-Mantel-Haenszel检验对分类数据进行分析 | Androwski, R. J. | N/A | Analysis of Categorical Data with Logistic Regression and the Cochran-Mantel-Haenszel Tests in Biological Experiments | |
| 苦味基因与口腔健康：加拿大老龄化纵向研究 | Shafizadeh, M. | N/A | Bitter taste genetics and oral health in Canadian Longitudinal Study on Aging | |
| 多视角最佳线性无偏预测（Multi-view BLUP）：一种有前景的后组学数据整合预测方法 | Wu, B. | N/A | Multi-view BLUP: a promising solution for post-omics data integrative prediction | |
| 端粒重复序列含RNA在老化的人类细胞中增加 | Chu, H.-P. C. | N/A | Telomeric Repeat-Containing RNA Increases in Aged Human Cells | |
| CUT&RUN峰值调用方法的基准测试 | Nooranikhojasteh, A. | N/A | Benchmarking Peak Calling Methods for CUT&RUN | |
| 对PeptideAtlas数据库的深入审计揭示了未注释编码基因和异常翻译的证据。 | Rodriguez, J. M. | N/A | A deep audit of the PeptideAtlas database uncovers evidence for unannotated coding genes and aberrant translation | |
| DNA拓扑异构酶Top2的减少能够重新编程表观遗传景观，并在多个物种中延长健康和寿命。 | Zhu, M. | N/A | Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species | |
| 来自L. meyenii Walp的脂质纳米颗粒通过多模态蛋白质冠形成减轻脓毒症 | Sung, J. J. | N/A | Lipid Nanoparticles from L. meyenii Walp Mitigate Sepsis through Multimodal Protein Corona Formation | |
| 预测喉镜图像中的语义分割质量 | Kist, A. M. | N/A | Predicting semantic segmentation quality in laryngeal endoscopy images | |
| 体积成像与计算技术在斑马鱼心脏收缩功能研究中的应用 | Saberigarakani, A. | N/A | Volumetric imaging and computation to explore contractile function in zebrafish hearts | |
| 非角化颊部组织在负压冲击下的有限元模型 | Klein Cerrejon, D. | N/A | Finite element model of the non-keratinized buccal tissue under the impact of negative pressure | |
| SMAC：利用SMRT CCS数据在单分子水平上鉴定DNA N6-甲基腺苷（6mA） | Li, H. | N/A | SMAC: identifying DNA N6-methyladenine (6mA) at the single-molecule level using SMRT CCS data | |
| InterPLM：通过稀疏自编码器在蛋白质语言模型中发现可解释的特征 | Simon, E. | N/A | InterPLM: Discovering Interpretable Features in Protein Language Models via Sparse Autoencoders | |
| 利用蛋白质语言模型对蛋白质-肽结合亲和力进行排序 | Chalas, C. C. | N/A | Ranking protein-peptide binding affinities with protein language models | |
| 解密姜黄素对乳腺癌中组蛋白标记的表观遗传影响：基于3D网络的研究 | Tang, T. | N/A | Deciphering epigenetic influence of curcumin on histone signatures in breast cancer using 3D network | |
| Fast-Part：用于生物序列分析的快速且准确的数据分区工具 | Ahmed, S. | N/A | Fast-Part: Fast and Accurate Data Partitioning for Biological Sequence Analysis | |
| 评估肺炎链球菌中假定小RNA的保守性和目标 | Eichelman, M. C. | N/A | Assessing the conservation and targets of putative sRNAs in Streptococcus pneumoniae | |
| IMMClock揭示了免疫老化和T细胞功能在单细胞分辨率下的表现 | Schmidt, Y. G. | N/A | IMMClock reveals immune aging and T cell function at single-cell resolution | |
| 大规模定量交联与质谱技术为细胞器、细胞和组织内的蛋白质构象可塑性提供了新的见解 | Keller, A. | N/A | Large-Scale Quantitative Cross-Linking and Mass Spectrometry Provides New Insight on Protein Conformational Plasticity within Organelles, Cells, and Tissues | |
| NERVE 2.0：通过人工智能和用户友好的网络界面提升新增强反向疫苗学环境 | Conte, A. | N/A | NERVE 2.0: boosting the New Enhanced Reverse Vaccinology Environment via artificial intelligence and a user-friendly web interface | |
| 使用InMoose进行差异表达分析，InMoose是Python中的集成多组学开源环境 | Colange, M. | N/A | Differential Expression Analysis with InMoose, the Integrated Multi-Omic Open-Source Environment in Python | |
| 通过X射线散射和坐标建模对细菌微区室壳体的结构表征：细胞质蛋白偶然捕获的证据 | Zuo, X. | N/A | Structure Characterization of Bacterial Microcompartment Shells via X-ray Scattering and Coordinate Modeling: Evidence for adventitious capture of cytoplasmic proteins | |
| 肿瘤球体对荧光纳米金刚石的摄取受限于质量密度：一种四维光片检测法 | Niora, M. | N/A | Tumor Spheroid Uptake of Fluorescent Nanodiamonds is Limited by Mass Density: a 4D Light-Sheet Assay | |
| 在三维空间中量化单个纤维尺度的细胞牵引力：基于可变形光聚合纤维阵列的新方法 | Ucla, P. | N/A | Quantifying Cell Traction Forces at the Individual Fiber Scale in 3D: A Novel Approach Based on Deformable Photopolymerized Fiber Arrays | |
| 全片基质成像显示，密集纤维基质是II期结肠癌复发的高风险因素 | Ravensbergen, C. | N/A | Whole-Slide ECM Imaging Reveals Dense Fibrous Matrix as a High-Risk Factor for Recurrence in Stage II Colon Cancer | |
| 发育阶段与细胞背景决定Ezh2Y641F突变在造血中的致癌与分子结果 | Zimmerman, S. M. | N/A | Developmental Stage and Cellular Context Determine Oncogenic and Molecular Outcomes of Ezh2Y641F Mutation in Hematopoiesis | |
| 癌症细胞中p53对SOX2的转录抑制调控细胞身份和迁移 | Lado-Fernandez, P. | N/A | Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration | |
| ecPath 通过组织病理学图像检测肿瘤中的ecDNA | Choudhury, M. | N/A | ecPath detects ecDNA in tumors from histopathology images | |
| 鉴定Ephrin B型受体4为组织纤维化的关键介质 | Wu, B. R.-L. | N/A | Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis | |
| 成纤维细胞衍生的骨糖蛋白促进上皮细胞修复 | van der Koog, L. | N/A | Fibroblast-derived osteoglycin promotes epithelial cell repair | |
| 腓肠肌俯卧撑对糖尿病前期患者血糖耐受性的影响 | Elek, D. | N/A | The effects of soleus push up on glucose tolerance among individuals with prediabetes | |
| 源自生物衰老组织学特征的组织时钟能够从血液中进行组织特异性衰老预测 | Abila, E. | N/A | Tissue clocks derived from histological signatures of biological aging enable tissue-specific aging predictions from blood | |
| OPN5和TRPV4在小鼠角膜上皮的内源性光敏感性中起作用。 | Lapajne, L. | N/A | OPN5 and TRPV4 subserve intrinsic photosensitivity in mouse corneal epithelium | |
| 对哺乳动物分泌途径的重建揭示了调控抗体生产的机制 | Masson, H. | N/A | A reconstruction of the mammalian secretory pathway identifies mechanisms regulating antibody production | |
| 一种新颖而简单的操作方法大大提高了大鼠肝脏移植的成功率。 | Chen, Y. | N/A | A novel and simple maneuver greatly improves rat liver transplantation | |
| 单细胞图谱的描绘为川崎病冠状动脉病变的发展提供了新的见解：坏与好的信号分子 | Lin, Q. | N/A | Delineation of Single-cell Altas Provides New Insights for Development of Coronary Artery Lesions in Kawasaki Disease: Bad and Good Signaling Molecules | |
| 规范的Notch2信号调节铁回收巨噬细胞的发育和铁稳态 | Schroth, F. N. | N/A | Canonical Notch2 Signaling Regulates the Development of Iron-recycling Macrophages and Iron Homeostasis | |
| 木制奶酪熟化板上的微生物群是产生抗李斯特菌单核细胞增生菌的抗菌细菌的丰富来源。 | Chen, Y. | N/A | The microbiota of wooden cheese ripening boards is a rich source of antimicrobial-producing bacteria against Listeria monocytogenes | |
| 综合蛋白质组和脂质组分析将OCIAD1定位于线粒体与过氧化物酶体的交汇处，平衡脂质代谢 | Linke, V. | N/A | Integrated proteome and lipidome analyses place OCIAD1 at mitochondria-peroxisome intersection balancing lipid metabolism | |
| 抑制酸性神经酰胺酶作为一种治疗尼曼-皮克C病的治疗策略 | Haynes, I. | N/A | Inhibition of acid ceramidase as a therapeutic strategy for Niemann-Pick C disease | |
| 通过两亲性螺旋在内核膜上感知脂质松动的参数 | Lee, S. | N/A | Parameters for sensing lipid loosening at the inner nuclear membrane by amphipathic helices | |
| 在颗石藻生物矿化过程中富钙区室的动态变化 | Triccas, A. | N/A | Dynamic change of calcium-rich compartments during coccolithophore biomineralization | |
| ATF4通过调节线粒体功能障碍、线粒体自噬和自噬，在Fuchs营养不良症中慢性内质网应激下促进角膜内皮细胞凋亡。 | Qureshi, S. | N/A | ATF4 regulates mitochondrial dysfunction, mitophagy, and autophagy, contributing to corneal endothelial apoptosis under chronic ER stress in Fuchs dystrophy | |
| TUDCA通过调节药物生物利用度来调控酿酒酵母对急性内质网应激的抗性 | Chadwick, S. R. | N/A | TUDCA modulates drug bioavailability to regulate resistance to acute ER stress in Saccharomyces cerevisiae | |
| PCMD-1稳定了PCM支架并促进了中心粒的分离 | Schreiner, A. | N/A | PCMD-1 stabilizes the PCM scaffold and facilitates centriole separation | |
| 人工结构中优化的凹槽设计显著提高了珊瑚的定居和生存率 | Reichert, J. | N/A | Optimized recess design in artificial structures dramatically enhances coral settlement and survival | |
| 评估数据驱动的捕食者-猎物模型的保真度：动力系统分析 | Frank, A.-S. | N/A | Evaluating the Fidelity of Data-Driven Predator-Prey Models: A Dynamical Systems Analysis | |
| 时间至关重要：H5N1病毒在奶牛场的控制效果受限于其快速传播。 | DeWitt, M. E. | N/A | Time is of the essence: effectiveness of dairy farm control of H5N1 is limited by fast spread | |
| 探索珠穆朗玛峰绒布河流域冰川补给河流沉积物中的产甲烷古菌及其热响应 | Ma, W. | N/A | Exploring methanogenic archaea and their thermal responses in the glacier-fed stream sediments of Rongbuk River Basin, Mt. Everest | |
| 澳大利亚无刺蜜蜂的视觉生理学 | Penmetcha, B. | N/A | Visual physiology of Australian stingless bees | |
| 泛癌种有丝分裂DNA完整性检验点蛋白激酶的遗传特征 | Rasteh, A. M. | N/A | Pan-Cancer Genetic Profiles of Mitotic DNA Integrity Checkpoint Protein Kinases | |
| LIN-35和DREAM复合体促进温度应激诱导的秀丽隐杆线虫生殖细胞凋亡和胞质流动增加。 | Petrella, L. N. | N/A | LIN-35 and the DREAM complex promote temperature stress induced increases in germline apoptosis and cytoplasmic streaming in C. elegans | |
| 类固醇受体辅助加载调控前列腺癌细胞的转录反应 | Hiltunen, J. | N/A | Steroid receptor-assisted loading modulates transcriptional responses in prostate cancer cells | |
| 不确定性感知基因组深度学习与知识蒸馏 | Zhou, J. | N/A | Uncertainty-aware genomic deep learning with knowledge distillation | |
| Illumina Complete Long Read Ass测定法能够从人类肠道宏基因组中生成连续的细菌基因组。 | Maghini, D. G. | N/A | Illumina Complete Long Read Assay yields contiguous bacterial genomes from human gut metagenomes | |
| 可点击的聚乙二醇-降冰片烯微凝胶支持悬浮生物打印和微血管组装 | Zhang, I. W. | N/A | Clickable PEG-norbornene microgels support suspension bioprinting and microvascular assembly | |
| 利用蛋白质结构图嵌入预测错义变异的致病性 | Danner, M. | N/A | Utilizing protein structure graph embeddings to predict the pathogenicity of missense variants | |
| 使用穷尽蛋白质搜索和Alphafold2进行蛋白质搜索漂移的特征化 | Buchan, D. W. | N/A | Characterising Protein Search Drift using exhaustive protein search and Alphafold2 | |
| miRBench：一个全面的微RNA结合位点预测训练和基准测试数据集 | Sammut, S. | N/A | miRBench: A Comprehensive microRNA Binding Site Prediction Training and Benchmarking Dataset | |
| 阿努比斯：一种利用随机森林分类法对古代蛋白质进行多层次鉴定的方法 | Chiang, Y. | N/A | Anubis: a multi-level authentication scale for ancient proteins using random forest classification | |
| STABIX：基于摘要统计的全基因组关联分析索引与压缩 | Schneider, K. | N/A | STABIX: Summary statistic-based GWAS indexing and compression | |
| TSniffer：在RNA-seq数据中无偏倚地从头鉴定RNA编辑位点并量化编辑活性 | Herrmann, M. | N/A | TSniffer: Unbiased de novo identification of RNA editing sites and quantification of editing activity in RNA-seq data | |
| 语言模型引导的未知代谢物预测与发现 | Qiang, H. | N/A | Language model-guided anticipation and discovery of unknown metabolites | |
| CLUEY 能够从单细胞组学数据中实现知识引导的聚类和细胞类型检测。 | Kim, D. | N/A | CLUEY enables knowledge-guided clustering and cell type detection from single-cell omics data | |
| 构建基于单细胞转录组的坐标系统用于细胞ID识别的SURE方法 | Zeng, F. | N/A | Building a single cell transcriptome-based coordinate system for cell ID with SURE | |
| 脂质组成在体外和体内系统之间的铁死亡敏感性上存在差异 | Park, V. S. | N/A | Lipid composition differentiates ferroptosis sensitivity between in vitro and in vivo systems | |
| 过氧化物酶表达在肿瘤内毛细血管和邻近透明细胞肾细胞癌的近端小管细胞中增加。 | Pestana e Silva, R. N. | N/A | Peroxidasin expression is increased in intratumoural capillaries and in proximal tubular cells adjacent to clear cell renal cell carcinoma. | |
| 司美格鲁肽诱导的体重减轻改善了骨骼肌线粒体能量效率 | Choi, R. H. | N/A | Semaglutide-induced weight loss improves mitochondrial energy efficiency in skeletal muscle | |
| 数字免疫优化血凝素与纳米笼插接展示技术激发广泛中和的全H5流感亚型疫苗反应 | Huang, C. Q. | N/A | Digitally immune optimised haemagglutinin with nanocage plug-and-display elicits broadly neutralising pan-H5 influenza subtype vaccine responses | |
| 抗HIV-1 B细胞抗原受体信号传导与结构 | Thakur, B. | N/A | Anti-HIV-1 B cell antigen receptor signaling and structure | |
| 炎症相关单核细胞表达ACOD1以遏制炎症行为在IBD和实验性结肠炎中 | Jones, G.-R. | N/A | Inflammation-associated monocytes express ACOD1 to curtail inflammatory behaviour in IBD and experimental colitis | |
| 血吸虫食道腺因子MEG-8.2驱动宿主细胞裂解并与其免疫蛋白相互作用 | Yadav, P. | N/A | Schistosome esophageal gland factor MEG-8.2 drives host cell lysis and interacts with host immune proteins | |
| 衣原体质粒编码蛋白Pgp2是一种复制起始蛋白，具有独特的β-发夹结构，对于与迭代子结合及质粒复制至关重要。 | Wan, D. | N/A | Chlamydia plasmid-encoded protein Pgp2 is a replication initiator with a unique beta-hairpin necessary for iteron-binding and plasmid replication | |
| 利用蛋白质语言模型进行基于结构的发现，以获得高效且稳定的PET水解酶 | Wu, B. | N/A | Harnessing Protein Language Model for Structure-Based Discovery of Highly Efficient and Robust PET Hydrolases | |
| 新型CRITR-seq方法揭示了流感转录受到NELF的调控，并且是引发干扰素反应的关键事件。 | Vicary, A. C. | N/A | Novel CRITR-seq approach reveals influenza transcription is modulated by NELF and is a key event precipitating an interferon response | |
| 维生素E、高密度脂蛋白及B型1类清道夫受体对脂质氧化与铁死亡的生理调节作用 | Rink, J. S. | N/A | Physiologic Regulation of Lipid Oxidation and Ferroptosis By Vitamin E, High-Density Lipoprotein, and Scavenger Receptor Class B Type 1 | |
| 一类新型变构葡萄糖脑苷脂酶β1校正剂，可减轻细胞应激并增强溶酶体功能 | Fregno, I. | N/A | A novel class of allosteric glucosylceramidase beta 1 correctors that reduce cellular stress and enhance lysosomal function | |
| 城市树木多样性促进了鸟类食虫性，尽管随着城市化进程，鸟类多样性有所下降。 | Schille, L. | N/A | Urban tree diversity fosters bird insectivory despite a loss in bird diversity with urbanization | |
| 区分果蝇中轻度、重度及非典型过氧化物酶体生成障碍的PEX基因变异严重程度 | Gomez, V. A. | N/A | Distinguishing PEX gene variant severity for mild, severe, and atypical peroxisome biogenesis disorders in Drosophila | |
| PRC1和CTCF介导的从预备状态到活跃状态的染色质环转变驱动双价基因激活 | Hanafiah, A. | N/A | PRC1 and CTCF-Mediated Transition from Poised to Active Chromatin Loops Drives Bivalent Gene Activation | |
| mTORC1在溶酶体膜上整合生长因子和营养信号的结构基础 | Cui, Z. | N/A | Structural basis for growth factor and nutrient signal integration on the lysosomal membrane by mTORC1 | |
| 受缺陷的SNARE拉链或硬质脂质脂肪酸组成限制的膜融合反应对Sec17、Sec18和腺苷酸有不同的需求。 | Lopes, K. | N/A | Membrane fusion reactions limited by defective SNARE zippering or stiff lipid fatty acyl composition have distinct requirements for Sec17, Sec18, and adenine nucleotide | |
| 炎症巨噬细胞分泌的细胞因子调节了水凝胶生物材料上瓣膜间质细胞的性别差异 | Felix Velez, N. E. | N/A | Secreted cytokines from inflammatory macrophages modulate sex differences in valvular interstitial cells on hydrogel biomaterials | |
| Orthrus：一种基于人工智能、云端就绪且开源的混合方法，用于元蛋白质组学研究 | Chiang, Y. | N/A | Orthrus: an AI-powered, cloud-ready, and open-source hybrid approach for metaproteomics | |
| 从Hi-C数据解读跨物种的三维基因组结构 | Shkolikov, A. | N/A | Deciphering the 3D genome organization across species from Hi-C data | |
| 识别相互作用神经退行性蛋白质之间的铜配位环境：使用14N/15N同位素标记的脉冲EPR新方法 | Smart, A. | N/A | Identifying the Copper Coordination Environment Between Interacting Neurodegenerative Proteins: A New Approach Using Pulsed EPR with 14N/15N Isotopic Labelling | |
| 上皮细胞中HKDC1的缺失减缓了细胞增殖，并损害了肿瘤性上皮细胞的线粒体功能，从而保护小鼠免受肠道癌变的影响。 | Jaerke, L. | N/A | Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis in mice | |
| 过敏性肺炎中的T细胞受体共享 | Sendama, W. | N/A | T cell receptor sharing in hypersensitivity pneumonitis | |
| 替代性cGAS信号传导促进单纯疱疹性脑炎 | Shmuel-Galia, L. | N/A | Alternative cGAS signaling promotes Herpes simplex encephalitis | |
| 转录组学预测夜间人工光照（ALAN）对适应性的影响：夜间光照改变了摇蚊（Chironomus riparius，双翅目：摇蚊科）的基因表达模式，并对适应性成分产生负面影响 | Eberhardt, L. | N/A | Transcriptomics predicts Artificial Light at Night's (ALAN) impact on fitness: nightly illumination alters gene expression pattern and negatively affects fitness components in the midge Chironomus riparius (Diptera:Chironomidae) | |
| 多聚核糖体和mRNA调控真核细胞胞质的生物物理特性 | Gade, V. R. | N/A | Polysomes and mRNA control the biophysical properties of the eukaryotic cytoplasm | |
| 无序玻璃纳米线基底通过光学衍射断层成像揭示了类似体内星形胶质细胞的形态 | Anantha, P. | N/A | Disordered glass nanowire substrates produce in vivo-like astrocyte morphology revealed by optical diffraction tomography | |
| TSSK同源物调控按蚊精氨酸和斯氏按蚊睾丸特异性基因的表达 | Meghwanshi, K. K. | N/A | TSSK homologue regulates the expression of protamine and mosquito testes specific genes in Anopheles stephensi | |
| 泛基因组参考序列改善了从肿瘤测序数据中生物标志物的估计 | Arslan, E. | N/A | Pangenome References Improve Biomarker Estimation from Tumor Sequencing Data | |
| 使用深度学习从基因表达预测泛癌药物敏感性 | Ocasio, B. A. | N/A | Pan-Cancer Drug Sensitivity Prediction from Gene Expression using Deep Learning | |
| 预测的细胞粘附分子MPZL3的丢失促进了卵巢癌中的上皮-间质转化和化学抗性 | Cheng, Y.-Y. | N/A | Loss of the predicted cell adhesion molecule MPZL3 promotes EMT and chemoresistance in ovarian cancer | |
| # BioRxiv 2024-11-14 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 从单细胞的动力学和几何结构中学习细胞特异性网络 | Zhang, S. Y. | N/A | Learning cell-specific networks from dynamics and geometry of single cells | |
| 计算机模拟兔眼和人眼中玻璃体内注射贝伐单抗后的药物分布 | Chowdhury, J. M. | N/A | Computer Modeling of Bevacizumab Drug Distribution after Intravitreal Injection in Rabbit and Human Eyes | |
| 用等效电路解释神经可塑性：一种机制性视角 | Nilsson, M. N. P. | N/A | Explaining neuroplasticity using equivalent circuits: A mechanistic perspective | |
| SNP分配用于估计遗传力（SAFE-h2）：一种用于探索表型基因组起源的工具，用于使用仅加性等位基因效应或加性和非加性等位基因效应估计SNP遗传力 | Darbani, B. | N/A | SNP Allocation For Estimating Heritability (SAFE-h2): A tool to explore genomic origins of phenotypes for estimation of SNP heritability using additive-only allelic effects or additive and non-additive allelic effects | |
| 通过高分辨率冷冻电镜结构揭示的APC/C的新结构特征：apo-APC/C和APC/C CDH1:EMI1复合物的结构 | Hoefler, A. | N/A | New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C CDH1:EMI1 complex | |
| 致幻剂5-HT2A受体激动作用：神经元特征与神经血管耦合的改变。 | Padawer-Curry, J. A. | N/A | Psychedelic 5-HT2A receptor agonism: neuronal signatures and altered neurovascular coupling. | |
| 海马中三种中间神经元群体的绝对数量及所有GABA能突触的绝对数量 | Takacs, V. | N/A | Absolute number of three populations of interneurons and all GABAergic synapses in the human hippocampus | |
| 膜电位介导细胞对机械压力的响应 | Mukherjee, A. | N/A | Membrane potential mediates the cellular response to mechanical pressure | |
| 粘附斑衍生的液-液相分离调控mRNA翻译 | Kumar, A. | N/A | Focal adhesion-derived liquid-liquid phase separations regulate mRNA translation | |
| TRPV1和TRPM2在温暖温度检测中的不同作用 | Abd El Hay, M. Y. | N/A | Diverging roles of TRPV1 and TRPM2 in warm-temperature detection | |
| 无细胞优化生产原卟啉IX | Garcia, D. C. | N/A | Cell-Free Optimized Production of Protoporphyrin IX | |
| 短链脂肪酸代谢产物丙酸和丁酸是独特的表观遗传调控因子，连接着饮食、代谢和基因表达。 | Nshanian, M. | N/A | Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression | |
| 基于逻辑的生物网络建模与Netflux | Clark, A. P. | N/A | Logic-based modeling of biological networks with Netflux | |
| 利用大型语言模型揭示人脑中的多层次和多模态语义表征 | Nakagi, Y. | N/A | Unveiling Multi-level and Multi-modal Semantic Representations in the Human Brain using Large Language Models | |
| 抗漂移姿态追踪器（ADPT）：一种基于Transformer的网络，用于跨物种的稳健动物姿态估计 | Tang, G. | N/A | Anti-drift pose tracker (ADPT): A transformer-based network for robust animal pose estimation cross-species | |
| 所有细菌基因组 - 已组装、可用且可搜索的细菌基因组数据库 | Hunt, M. | N/A | AllTheBacteria - all bacterial genomes assembled, available and searchable | |
| 患者来源的ccRCC类器官单细胞中异质性和新型转录本的表达 | Karakulak, T. | N/A | Heterogeneous and Novel Transcript Expression in Single Cells of Patient-Derived ccRCC Organoids | |
| 在变暖和干燥的气候条件下，热带干旱森林树木的叶部和生殖物候的量和时间变化 | Lai, H. R. | N/A | Changes in quantity and timing of foliar and reproductive phenology of tropical dry-forest trees under a warming and drying climate | |
| 在主动舔食的小鼠中，皮层对味觉和温度信号的编码 | Nash, A. N. | N/A | Cortical Coding of Gustatory and Thermal Signals in Active Licking Mice | |
| 受损的卵黄囊NAD代谢会破坏小鼠胚胎发育，这与人类出生缺陷有关。 | Bozon, K. | N/A | Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects | |
| 一个用于抗体序列理解的生成基础模型 | Barton, J. | N/A | A generative foundation model for antibody sequence understanding | |
| 比较群体基因组学揭示了西南太平洋热液喷口区一致的次级缝合带 | Tran Lu Y, A. | N/A | Comparative population genomics unveils congruent secondary suture zone in Southwest Pacific Hydrothermal Vents | |
| iHDSel软件：利用Price方程和群体稳定性指数检测与选择性清除相符的基因组模式。以SARS-CoV-2为例。 | Carvajal-Rodriguez, A. | N/A | iHDSel software: The Price equation and the population stability index to detect genomic patterns compatible with selective sweeps. An example with SARS-CoV-2. | |
| 对秀丽隐杆线虫中Smad和Schnurri转录因子的全基因组分析显示了它们广泛的相互作用，并在胶原蛋白分泌中发挥功能。 | Vora, M. | N/A | Genome-wide analysis of Smad and Schnurri transcription factors in C. elegans demonstrates widespread interaction and a function in collagen secretion | |
| 开源自动化通用高内涵多重荧光RNA原位分析（AURA）协议 | Descarpentrie, J. | N/A | Protocol for open-source Automated Universal high-content multiplex fluorescence for RNA in situ Analysis (AURA) | |
| 草莓COP9信号体FvCSN5A通过促进多胺氧化酶FvPAO5的降解，调控植物发育和果实成熟，从而控制多胺和H2O2的稳态。 | Huang, Y. | N/A | Strawberry COP9 signalosome FvCSN5A regulates plant development and fruit ripening by facilitating polyamine oxidase FvPAO5 degradation to control polyamine and H2O2 homeostasis | |
| 在小鼠中，绿茶化合物在饮用绿茶后的血浆中出现的情况受到肠道微生物群的调节。 | Sterrett, J. D. | N/A | Appearance of green tea compounds in plasma following acute green tea consumption is modulated by the gut microbiome in mice | |
| 空间变异竞争导致植物适应性和分布对环境梯度的反应不匹配 | Hayashi, K. T. | N/A | Spatially variable competition contributes to mismatched responses of plant fitness and occurrence to environmental gradients | |
| 来自韩国都湖组（中新世）的新鲣鱼标本（属名Auxis） | Suh, D. | N/A | A new tuna specimen (Genus Auxis) from the Duho Formation (Miocene) of South Korea | |
| 细胞类型特异性调控TOR介导的微管乙酰化预测Yki丢失诱导的果蝇鳞状细胞癌 | Bhattacharya, R. | N/A | Cell-Type-Specific Regulation of TOR-Mediated Microtubule Acetylation Predicts Yki Loss-Induced Squamous Cell Carcinoma in Drosophila | |
| 是我还是火车在动？人类在平衡控制中通过一种非线性反馈机制来解决感官冲突。 | Asslaender, L. | N/A | Is it me or the train moving? Humans resolve sensory conflicts with a nonlinear feedback mechanism in balance control | |
| 操作性酒精自我给药以一种驱动药物强化特性的方式，靶向含有GluA2的AMPAR表达和伏隔核中的突触活动。 | Faccidomo, S. | N/A | Operant alcohol self-administration targets GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens in a manner that drives the reinforcing properties of the drug | |
| 不活动介导的分子适应：从体力活动减少的临床前模型中获得的见解 | Meyer, A. | N/A | Inactivity-mediated molecular adaptations: insights from a pre-clinical model of physical activity reduction | |
| C57BL/6J小鼠在家庭笼中饮用乙醇和操作性自我给药方面的性别差异，但谷氨酸AMPAR活性调节的等效性 | Faccidomo, S. | N/A | Sex Differences in Home-Cage Ethanol Drinking and Operant Self-Administration in C57BL/6J Mice but Equivalent Regulation by Glutamate AMPAR Activity | |
| 利用吉布斯振铃衰减的T1w/T2w-FLAIR髓鞘MRI绘制皮层特定层区域边界图 | Autio, J. A. | N/A | Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI | |
| 通过完全自主的HABITS系统实现新颖且优化的鼠标行为：家庭笼辅助行为创新与测试系统 | Yu, B. | N/A | Novel and optimized mouse behavior enabled by fully autonomous HABITS: Home-cage Assisted Behavioral Innovation and Testing System | |
| Pannexin-2 缺陷破坏视觉通路并导致斑马鱼眼部缺陷 | Shanbhag, R. | N/A | Pannexin-2 deficiency disrupts visual pathways and leads to ocular defects in zebrafish | |
| 血液培养物中含有遗传多样性的白色念珠菌菌株，这些菌株在棘白菌素耐药性和毒力方面可能存在差异。 | Fleres, G. | N/A | Blood cultures contain populations of genetically diverse Candida albicans strains that may differ in echinocandin tolerance and virulence | |
| 高度多孔的颗粒状水凝胶，通过静电纺丝水凝胶纤维增强，以实现长期稳定性 | Whitewolf, J. | N/A | Highly porous granular hydrogels reinforced by electrospun hydrogel fibers for long-term stability | |
| 化石记录中稀疏时间序列的反应规范适应度峰值追踪 | Ergon, R. | N/A | Reaction norm fitness peaks tracking applied on sparse time series in the fossil record | |
| 岛屿人口统计学：哥特兰岛标志性金雕的繁殖动态及驱动因素 | Singh, N. J. | N/A | Island population demography: Breeding dynamics and drivers of Gotland's iconic Golden Eagles | |
| 无标记鸟枪法蛋白质组学中监测宿主细胞蛋白的MS/MS搜索算法比较分析，采用捕获离子淌度和ddaPASEF技术 | Khalil, S. | N/A | Comparative analysis of MS/MS search algorithms in label-free shotgun proteomics for monitoring host-cell proteins using trapped ion mobility and ddaPASEF | |
| 雌蛾将植物的声发射纳入其产卵决策中 | Seltzer, R. | N/A | Female Moths Incorporate Plant Acoustic Emissions into Their Oviposition Decision | |
| 新生转录本O-MAP揭示了由RBM20和TTN RNA构建的单基因位点亚核区室的分子结构 | Kania, E. E. | N/A | Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the TTN RNA | |
| 抑郁症和焦虑症中基底前脑对内在脑网络的调控改变 | Jamieson, A. J. | N/A | Altered basal forebrain regulation of intrinsic brain networks in depressive and anxiety disorders | |
| 在人类和小鼠胰岛素中，一种翻译后将半胱氨酸转化为丝氨酸的转变，产生了一种糖尿病新表位。 | Srivastava, N. | N/A | A post-translational cysteine-to-serine conversion in human and mouse insulin generates a diabetogenic neoepitope | |
| 资源环境塑造了人类阴道微生物群的组成和稳定性。 | Kamiya, T. | N/A | Resource landscape shapes the composition and stability of the human vaginal microbiota | |
| ER Ca2+水平通过调节L型Ca2+通道活性来控制神经调质的分泌。 | Hoogstraaten, R. I. | N/A | ER Ca2+-levels control neuromodulator secretion by regulating L-type Ca2+-channel activity | |
| 在一年的时间里，孟加拉国各地的霍乱弧菌谱系和泛基因组多样性存在地理差异。 | Qin, C. | N/A | Vibrio cholerae lineage and pangenome diversity varies geographically across Bangladesh over one year | |
| 有丝分裂CIP2A-TOPBP1轴促进有丝分裂途径在MiDAS和MMEJ之间的选择。 | Martin, P. R. | N/A | The mitotic CIP2A-TOPBP1 axis facilitates mitotic pathway choice between MiDAS and MMEJ | |
| 重度抑郁症外周血单个核细胞神经免疫网络中突触相关基因的失调 | Adri, A. | N/A | Dysregulation of synaptic-related genes within neuroimmune networks of peripheral blood mononuclear cells in major depressive disorder | |
| 比较用于预测急性髓系白血病患者突变状态的机器学习模型，使用RNA测序数据 | Silva, R. | N/A | Comparing machine learning models for predicting mutation status in Acute Myeloid Leukemia patients using RNA-seq data | |
| 加拿大早期职业健康研究人员特征及COVID-19疫情期间的职业倦怠经历 | Hewko, S. | N/A | Characteristics of early career health researchers and experiences of burnout during the COVID-19 pandemic in Canada | |
| 我们是意识的传感器！关于睡眠中的觉醒如何影响梦境回忆的回顾与分析。 | Stucky, B. | N/A | We are the sensors of consciousness! A review and analysis on how awakenings during sleep influence dream recall. | |
| 坦桑尼亚南部伊法卡拉-卢皮罗-曼古拉野生动物管理区的利益相关者对其有效性的看法 | Tarimo, L. J. | N/A | Stakeholder perspectives on the effectiveness of the Ifakara-Lupiro-Mang'ula Wildlife Management Area in Southern Tanzania | |
| 对GWAS汇总统计数据的稀疏矩阵分解，能够稳健地处理样本共享问题，从而提高对具有多样遗传结构的因素的检测和解释能力。 | Omdahl, A. R. | N/A | Sparse matrix factorization of GWAS summary statistics robust to sample sharing improves detection and interpretation of factors with diverse genetic architectures | |
| 量化颅骨整骨手法对阿尔茨海默病野生型和转基因大鼠模型的影响 | Hines, D. | N/A | Effect of quantified cranial osteopathic manipulation on wild type and transgenic rat models of Alzheimer's disease | |
| 经典三叉神经痛患者的脑老化 | Cruz-Almeida, Y. | N/A | Brain Aging Among Individuals with Classical Trigeminal Neuralgia | |
| 在实体瘤基质中异常表达的X型胶原蛋白与上皮-间质转化、免疫抑制和促转移通路、骨髓基质细胞特征以及不良的生存预后相关。 | Famili-Youth, E. H. H. | N/A | Aberrant expression of collagen type X in solid tumor stroma is associated with EMT, immunosuppressive and pro-metastatic pathways, bone marrow stromal cell signatures, and poor survival prognosis | |
| 饮食和非酶氧化固醇在子痫前期胎盘中的积累：对妊娠并发症中胆固醇动态的见解 | Zou, L. | N/A | Accumulation of Dietary and Non-Enzymatic Oxysterols in Preeclamptic Placentas: Insights into Cholesterol Dynamics in Pregnancy Complications | |
| 母亲运动方式对婴儿脐带血蛋白质组的影响 | Jevtovic, F. | N/A | Effects of maternal exercise modes on infant cord blood proteome | |
| 小窝蛋白-1和水通道蛋白-4作为遗传性脑淀粉样血管病中纤维蛋白原驱动脑血管病理的介质 | Singh, V. | N/A | Caveolin-1 and Aquaporin-4 as Mediators of Fibrinogen-Driven Cerebrovascular Pathology in Hereditary Cerebral Amyloid Angiopathy | |
| 使用高灵敏度磷脂酰丝氨酸结合试剂在体内评估细胞外囊泡的周转 | Flaskamp, L. | N/A | Assessing Extracellular Vesicle Turnover In vivo Using Highly Sensitive Phosphatidylserine-Binding Reagents | |
| 在有鳞目深系谱中，核与线粒体氧化磷酸化复合体亚基的趋同进化证据 | Wallnoefer, O. | N/A | Evidence of convergent evolution in the nuclear and mitochondrial OXPHOS subunits across the deep lineages of Squamata | |
| 通过张量分解重构RNA-断层扫描转录组的三维空间结构 | Song, T. | N/A | Reconstructing 3D Spatial Structures of RNA-Tomography Transcriptomes by Tensor Factorization | |
| 全蛋白质组反向分子对接揭示叶酸受体作为PFAS诱导神经发育毒性的介质 | Kong, A. X. | N/A | Proteome-wide reverse molecular docking reveals folic acid receptor as a mediator of PFAS-induced neurodevelopmental toxicity | |
| 调控Koisio技术生产的流体对血管外膜间质液流动的影响及其通过输送艾司洛尔对心率的作用 | Li, B. | N/A | Regulating of Koisio technology-produced fluid on Vascular Adventitial Interstitial Fluid flow and its Effect on heart rate by delivering Esmolol | |
| 蛋白质-蛋白质相互作用是遗传相互作用网络中上位性的主要来源 | Castellanos-Girouard, X. | N/A | Protein-protein interaction is a major source of epistasis in genetic interaction networks | |
| 坏死性脑膜脑炎中的星形胶质细胞功能障碍、脱髓鞘和结节性炎症 | Hernandez, S. I. | N/A | Astroglial Dysfunction, Demyelination and Nodular inflammation in Necrotizing Meningoencephalitis | |
| 在竞争性生态系统中多重稳定平衡的结构 | Taylor, W. | N/A | On the structure of multiple stable equilibria in competitive ecological systems | |
| scPrediXcan将深度学习和单细胞数据的进展整合到一个强大的细胞类型特异性转录组关联研究框架中。 | Zhou, Y. | N/A | scPrediXcan integrates advances in deep learning and single-cell data into a powerful cell-type-specific transcriptome-wide association study framework | |
| 底物和产物选择性尼龙水解酶的鉴定与表征 | Drufva, E. | N/A | Identification and characterization of substrate- and product-selective nylon hydrolases | |
| 金属水解酶的计算设计 | Kim, D. | N/A | Computational Design of Metallohydrolases | |
| 大鼠颞下颌关节中锌特异性髁突区的硫物种 | Lee, B. H. | N/A | Sulfur-species in Zinc-specific Condylar Zones of a Rat Temporomandibular Joint | |
| PYR1生物传感器驱动的克鲁维酵母基因组范围CRISPR筛选，以提高单萜类化合物生产 | Robertson, N. R. | N/A | PYR1 biosensor-driven genome-wide CRISPR screens for improved monoterpenoid production in Kluyveromyces marxianus | |
| 心脏组织中早期后去极化驱动的心律失常机制 | Stein, J. | N/A | Mechanism of Arrhythmogenesis Driven by Early After Depolarizations in Cardiac Tissue | |
| 快速反应特质在感觉运动皮层中的Mu和Beta节律效应在提示前和运动执行期间表现出双重分离 | Kamali, S. | N/A | Mu and beta power effects of fast response trait double dissociate during precue and movement execution in the sensorimotor cortex | |
| 通信子空间与人工神经网络的训练相一致 | Poggi, P. G. | N/A | Communication subspaces align with training in ANNs | |
| 紫外线诱导的DNA修复机制及其对大肠杆菌突变性和培养能力的影响 | Ghosh, S. | N/A | UV-Induced DNA Repair Mechanisms and Their Effects on Mutagenesis and Culturability in Escherichia coli | |
| 布氏锥虫的糖体ATP依赖性磷酸果糖激酶在体内类似条件下，在细胞内以糖异生方向进行操作。 | Plazolles, N. | N/A | The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei operates in the gluconeogenic direction in cellulo under in vivo-like conditions | |
| Mcm3中一个必需的核定位序列的序列特异性 | Wang, Z. | N/A | Sequence specificity of an essential nuclear localization sequence in Mcm3 | |
| 生物膜形成和生态位适应在塑造远距离运输的尘埃微生物群落中起着基础性作用。 | Lang-Yona, N. | N/A | Biofilm Formation and Niche Adaptation Play Fundamental Role in Shaping Long-Distance Transported Dust Microbial Community | |
| 自然发生的、菌株特异性的鲍曼不动杆菌IV型菌毛回缩缺陷促进了生物膜的形成 | Yu, Y. | N/A | Naturally-occurring, strain-specific defects in the retraction of Acinetobacter baumannii type IV pili promote biofilm formation | |
| 揭示可可病原菌Moniliophthora perniciosa对嘧菌酯抗性的新机制 | do Prado, P. F. V. | N/A | Unveiling novel mechanisms of strobilurin resistance in the cacao pathogen Moniliophthora perniciosa | |
| 5500年前贝加尔湖狩猎采集者的致命瘟疫爆发 | Macleod, R. | N/A | Lethal Plague Outbreaks in Lake Baikal Hunter-gatherers 5500 Years Ago | |
| 基于活动的增强型碱基编辑器突变扫描的选择 | Kaplan, E. G. | N/A | Activity-based selection for enhanced base editor mutational scanning | |
| 使用MxP(R) Quant 500试剂盒对人血和啮齿动物血液进行标准化代谢组学和脂质组学分析的实验室间比较 | Zararsiz, G. E. | N/A | Interlaboratory comparison of standardised metabolomics and lipidomics analyses in human and rodent blood using the MxP(R) Quant 500 kit | |
| 通过着丝粒DNA序列增强的力传递至内着丝粒 | Miedlar, E. | N/A | Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences | |
| 基于机制的方法在设计针对无义突变疾病的个性化联合疗法中的应用 | Bhat, S. | N/A | Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases | |
| 动物编码的非核糖体途径合成bursatellin类似物。 | Schmidt, E. W. | N/A | Animal-encoded nonribosomal pathway to bursatellin analogs. | |
| RhoA通过其EF手结构域别构激活磷脂酶Cε | Ohri, V. | N/A | RhoA Allosterically Activates Phospholipase Cε via its EF Hands | |
| 杨树：一个系统发育学分析流程 | Krishnakumar, R. | N/A | Poplar: A Phylogenetics Pipeline | |
| 通过基于同源性和表示的分层聚类探索大型蛋白质序列空间 | Chen, J. Z. | N/A | Exploring large protein sequence space through homology- and representation-based hierarchical clustering | |
| 利用大型语言模型增强基因集富集分析 | Zhu, J. | N/A | Enhancing Gene Set Overrepresentation Analysis with Large Language Models | |
| 在科学会议上无法理解的图表 | Faulkes, Z. | N/A | Uninterpretable graphs at a scientific conference | |
| 外周CGRP参与偏头痛的脑电网络活动 | Johnson, M. S. | N/A | Peripheral CGRP engages brain-wide electrical network activity of migraine | |
| 社交焦虑改变了电影观看期间心智理论激活和跨受试者神经变异性的情况 | Mangnus, M. | N/A | Social Anxiety Alters Theory of Mind Activation and Intersubject Neural Variability During Movie Viewing | |
| 下调星形胶质细胞C3的产生可缓解tau病模型中的神经元线粒体功能障碍 | Lei, C. | N/A | Downregulation of astrocytic C3 production alleviates neuronal mitochondrial dysfunction in tauopathy models | |
| 学习后的休息有助于记忆巩固，并能逆转3xTg-AD小鼠在新环境中空间重定向能力的损伤。 | Stimmell, A. C. | N/A | Resting After Learning Facilitates Memory Consolidation and Reverses Spatial Reorientation Impairments in 'New Surroundings' in 3xTg-AD Mice | |
| FreeSurfer版本对帕金森病结构神经影像分析的影响 | Sokolowski, A. | N/A | The impact of FreeSurfer versions on structural neuroimaging analyses of Parkinson's disease | |
| 通过单细胞电感耦合等离子体质谱法快速精确量化淋巴细胞铁含量 | Holdship, P. | N/A | Rapid and precise quantification of lymphocyte iron content by single cell inductively coupled plasma mass spectrometry | |
| 约氏疟原虫的特化S型核糖体增强了宿主到媒介的疟疾传播 | McGee, J. P. | N/A | Specialized S-type ribosomes of Plasmodium yoelii enhance host-to-vector malaria transmission | |
| 在利什曼原虫（Leishmania major）中，核DNA复制依赖于每个染色体上的一个组成性起始点，并辅以数千次随机起始事件。 | Damasceno, J. D. | N/A | Nuclear DNA replication in Leishmania major relies on a single constitutive origin per chromosome supplemented by thousands of stochastic initiation events | |
| Cochlin的缺失导致肌腱结构和功能的损伤 | Adjei-Sowah, E. | N/A | Loss of Cochlin drives impairments in tendon structure and function | |
| SARS-CoV-2对宿主胆固醇的操控 | Doyle, A. | N/A | Manipulation of Host Cholesterol by SARS-CoV-2 | |
| 纳米孔数据类型、碱基识别与组装算法比较：单个MinION流式细胞仪的全植物基因组组装及甲基化分析 | Martin, S. | N/A | A Comparison of Nanopore Data Types, Basecalling, and Assembly Algorithms: Whole Plant Genome Assembly and Methylation Analysis from a Single MinION Flow cell | |
| 光亲和标记技术助力在天然细胞中转录组范围内鉴定剪接调控小分子-RNA结合事件 | Shah, R. | N/A | Photoaffinity enabled transcriptome-wide identification of splice modulating small molecule-RNA binding events in native cells | |
| 驱动神经退行性溶酶体贮积障碍模型中小胶质细胞表观遗传和转录反应的机制 | Balak, C. D. | N/A | Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model | |
| 内嗅皮层中的反复抑制性动态支持模式分离 | Zheng, Y. | N/A | Recurrent Inhibitory Dynamics in the Entorhinal Cortex Support Pattern Separation | |
| 7特斯拉下SNR高效的全脑伪连续动脉自旋标记灌注成像 | Woods, J. G. | N/A | SNR-Efficient Whole-Brain Pseudo-Continuous Arterial Spin Labeling Perfusion Imaging at 7 Tesla | |
| 转铁蛋白受体介导的血液-脑屏障运输在早期发育中升高，但在成年衰老过程中保持稳定。 | Torres, V. O. | N/A | Transferrin receptor-mediated transport at the blood-brain barrier is elevated in early development but maintained across adult aging | |
| 多尺度基于云的神经电生理分析与可视化管道 | Geng, J. | N/A | Multiscale Cloud-based Pipeline for Neuronal Electrophysiology Analysis and Visualization | |
| 在哺乳动物皮层胶质发生和胶质瘤发生过程中，通过Olig1/2调控少突胶质前体细胞与嗅球中间神经元的命运 | TIAN, Y. | N/A | Orchestrating the Acquisition of Oligodendrocyte Precursor Cell versus Olfactory Bulb Interneuron Fates through Olig1/2 during Mammalian Cortical Gliogenesis and Gliomagenesis | |
| 解码嗅结节中的中脑边缘多巴胺传递及其通过神经化学感应和化学遗传学对甲基苯丙胺反应的贡献 | Bhimani, R. V. | N/A | Decoding mesolimbic dopamine transmission in the olfactory tubercle and its contribution to methamphetamine responses through neurochemical sensing and chemogenetics | |
| 姜黄素通过CDK5/p35信号通路减轻小胶质细胞介导的慢性神经性疼痛 | Tong, F. | N/A | Curcumin attenuates microglia-mediated chronic neuropathic pain through CDK5 /p35 signaling pathway | |
| 空间工作记忆期间发作间期的尖波携带有助于或干扰空间表征，并对表现产生相反的影响。 | Yi, J. D. | N/A | Interictal spikes during spatial working memory carry helpful or distracting representations of space and have opposing impacts on performance. | |
| 黑质网状部至中缝背核的谷氨酸能投射促进小鼠的社会等级 | Fan, Y. | N/A | The Glutamatergic Projection from the Substantia Nigra Pars Reticulata to the Dorsal Raphe Nucleus Facilitates Social Hierarchy in Mice | |
| 受损的蛋白酶体引发线粒体DNA释放，激活小鼠脑中的cGAS-STING信号通路并导致坏死。 | Dwamena, A. | N/A | Impaired proteasome induces mitochondrial DNA release to activate the cGAS-STING signaling pathway and cause necroptosis in mouse brain | |
| 基于MRI的人类神经发育新生物型与冲动行为表现相关 | Zhou, Z. | N/A | Novel MRI-based Biotypes of Human Neurodevelopment associated with Impulsivity performance | |
| 不同频率的胡须刺激揭示了清醒大鼠感觉系统中功能性磁共振成像信号的非均匀调制 | Paasonen, J. | N/A | Whisker stimulation with different frequencies reveals non-uniform modulation of functional magnetic resonance imaging signal across sensory systems in awake rats | |
| 沙漠蝗虫听觉功能的性别差异 | Austin, T. | N/A | Sex differences in auditory function of the desert locust | |
| 在少突胶质细胞命运决定期间，procaspase-3的瞬时上调 | Kamen, Y. | N/A | Transient upregulation of procaspase-3 during oligodendrocyte fate decisions | |
| YORU：基于用户定义动物外观的深度学习社交行为检测 | YAMANOUCHI, H. M. | N/A | YORU: social behavior detection based on user-defined animal appearance using deep learning | |
| Nrf2 在成年小鼠大脑中以细胞类型特异性的方式调控体内平衡转录特征和炎症反应。 | He, X. | N/A | Nrf2 controls homeostatic transcriptional signatures and inflammatory responses in a cell-type specific manner in the adult mouse brain | |
| 间充质细胞衍生的细胞外囊泡改善了恒河猴工作记忆的年龄相关性缺陷以及脑部MRI和脑脊液中神经退行性变的体内生物标志物。 | Mackie, E. C. | N/A | Mesenchymal Cell-Derived Extracellular Vesicles Ameliorate Age-Related Deficits in Working Memory as well as Brain MRI and CSF in vivo Biomarkers of Neurodegeneration in Rhesus Monkeys. | |
| 中脑多巴胺D2R调节与威胁相关事件的显著性 | Castell, L. | N/A | Midbrain dopamine D2R regulates the salience of threat-related events | |
| 在自我思考期间，mPFC中认知过程的分解 | Levorsen, M. | N/A | Decomposing Cognitive Processes in the mPFC During Self-Thinking | |
| 低频皮层活动反映了依赖于语境的词序列解析 | Chen, H. | N/A | Low-frequency Cortical Activity Reflects Context-dependent Parsing of Word Sequences | |
| 小脑中的神经计算向量微积分 | Fakharian, M. A. | N/A | A vector calculus for neural computation in the cerebellum | |
| 成人脑膜的整合分层图谱 | Degenhard, T. | N/A | An integrative layer-resolved atlas of the adult human meninges | |
| 人类上行觉醒系统皮层下核团编码预期奖励，但不预测后续记忆 | Lloyd, B. | N/A | Subcortical nuclei of the human ascending arousal system encode anticipated reward but do not predict subsequent memory | |
| 基于钙的输入时序学习 | Kamalabad, S. S. | N/A | Calcium-based input timing learning | |
| 果糖-2,6-二磷酸恢复了运动神经元疾病中TDP-43病理驱动的基因组修复缺陷 | Mitra, J. | N/A | Fructose-2,6-bisphosphate restores TDP-43 pathology-driven genome repair deficiency in motor neuron diseases | |
| 果蝇神经元的独特非对称分支优化了时间树突计算 | Chou, P.-J. | N/A | Unique Asymmetric Branching of Drosophila Neurons Optimizes Temporal Dendritic Computation | |
| 猕猴外侧膝状体神经元的单细胞转录组分析揭示了新的亚群 | Sun, S. H. | N/A | Single-cell transcriptomic analysis of macaque LGN neurons reveals novel subpopulations | |
| 与加速的产后发育长期功能连接组相关的自发脑动力学 | Ma, L. | N/A | Spontaneous Brain Dynamics Associated With Acceleration Of Longterm Functional Connectome In Postnatal Development | |
| 深度神经网络解释了听觉皮层的尖峰活动 | Ahmed, B. | N/A | Deep Neural Networks Explain Spiking Activity in Auditory Cortex | |
| 肌萎缩侧索硬化症（ALS）大脑和脊髓中神经免疫区室的单细胞转录组图谱 | Tuddenham, J. | N/A | Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord | |
| 帕金森病患者在在线和离线运动序列学习中受损和增强 | Van Roy, A. | N/A | Impaired online and enhanced offline motor sequence learning in individuals with Parkinson's disease | |
| 在做出感知决策以在不同行动之间进行选择时，人类会预见运动控制需求的结果。 | Leroy, E. | N/A | Humans anticipate the consequences of motor control demands when making perceptual decisions between actions | |
| 降低蓝斑核去甲肾上腺素能信号传导至脊髓星形胶质细胞亚群是应激诱发疼痛易化所必需的。 | Kawanabe-Kobayashi, R. | N/A | Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced pain facilitation | |
| 价值对与任务无关的听觉失配负波无影响 | Hutchinson, B. T. | N/A | No Effect of Value on the Task Irrelevant Auditory Mismatch Negativity | |
| 病理性微电路在患者海马切片中启动癫痫样事件 | Elliott, M. | N/A | Pathological microcircuits initiate epileptiform events in patient hippocampal slices | |
| 工作记忆中感觉和运动内容的动态优先级排序 | Echeverria-Altuna, I. | N/A | Dynamic prioritisation of sensory and motor contents in working memory | |
| 星形胶质细胞连接蛋白43的磷酸化作用在轻度创伤性脑损伤后对癫痫易感性的影响 | Munoz-Ballester, C. | N/A | Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild Traumatic Brain Injury | |
| 恢复精神分裂症中的突触平衡：基于丘脑-皮层电导模型的见解。 | Berndt, L. C. S. | N/A | Restoring Synaptic Balance in Schizophrenia: Insights from a thalamo-cortical conductance-based model. | |
| 大鼠体感皮层血液流动动力学的建模 | Battini, S. | N/A | Modeling of blood flow dynamics in the rat somatosensory cortex | |
| 空间转录组学分析鉴定出一种表达SERPINA3的星形胶质细胞状态，与人类神经炎斑微环境相关 | Karaahmet, B. | N/A | Spatial Transcriptomic Analysis Identifies a SERPINA3-Expressing Astrocytic State Associated with the Human Neuritic Plaque Microenvironment | |
| 硫脂缺乏引起的星形胶质细胞增生和髓鞘脂质稳态失调与Trem2介导的微胶质细胞激活无关。 | Mittra, N. | N/A | Sulfatide deficiency-induced astrogliosis and myelin lipid dyshomeostasis are independent of Trem2-mediated microglial activation | |
| miR-29a调控对成年大脑记忆稳定性的双向影响 | Viglione, A. | N/A | Bidirectional Impact of miR-29a modulation on Memory Stability in the Adult Brain | |
| 一种基于PET的功能激活和分子连接识别的统一方法，借助功能PET工具箱实现 | Hahn, A. | N/A | A Unified Approach for Identifying PET-based Neuronal Activation and Molecular Connectivity with the functional PET toolbox | |
| 由特定亚型TrkB-T1序列建立的相互作用调控中风中的炎症反应和神经毒性 | Ugalde-Trivino, L. | N/A | Interactions established by isoform-specific TrkB-T1 sequences govern inflammatory response and neurotoxicity in stroke | |
| 使用潜在状态逆强化学习建模复杂动物行为 | Jha, A. | N/A | Modeling Complex Animal Behavior with Latent State Inverse Reinforcement Learning | |
| 年长即有序：皮层自发活动的熵减少标志着健康衰老 | Chang, D. | N/A | Older is Order: Entropy reduction in cortical spontaneous activity marks healthy aging | |
| 脑功能网络连接插值法表征了神经精神连续谱与异质性 | Li, X. | N/A | Brain functional network connectivity interpolation characterizes neuropsychiatric continuum and heterogeneity | |
| 大规模脑干记录中尖峰分类器的比较分析 | De Preter, C. C. | N/A | Comparative analysis of spike-sorters in large-scale brainstem recordings | |
| 多模态探究成年阅读障碍背后的神经认知缺陷 | Cara, C. | N/A | Multimodal investigation of the neurocognitive deficits underlying dyslexia in adulthood | |
| 性相关基因表达在循环雌性大鼠后内侧杏仁核中的表现以及催乳素对雌性大鼠交配行为的影响 | Buhler, L. | N/A | SEX-RELATED GENE EXPRESSION IN THE POSTERODORSAL MEDIAL AMYGDALA OF CYCLING FEMALE RATS ALONG WITH PROLACTIN MODULATION OF LORDOSIS BEHAVIOR | |
| 特征相似性：一种敏感的方法，用于捕捉脑区和网络的功能相互作用，以支持灵活的行为 | Wang, X. | N/A | Feature similarity: a sensitive method to capture the functional interaction of brain regions and networks to support flexible behavior | |
| 核糖体丰度，而非旁系同源基因组成，对生殖系发育至关重要 | Grobicki, K. Z. A. | N/A | Ribosome abundance, not paralogue composition, is essential for germline development | |
| 钙信号传导在小鼠胚胎的前部模式形成中是必需的。 | Stower, M. | N/A | Calcium signalling is required for anterior patterning in the mouse embryo | |
| 在终末期红细胞生成过程中，血红蛋白的高效生产依赖于TENT5C多聚腺苷酸聚合酶与LARP4/5的协同作用。 | Mazur, M. | N/A | Efficient globin production during terminal erythropoiesis depends on the synergistic action of TENT5C poly(A) polymerase and LARP4/5 | |
| PP2A磷酸酶在Hippo信号调控中具有双重作用 | Sekar, A. | N/A | A Dual Role for the PP2A Phosphatase in Hippo Signalling Regulation | |
| Hox13通过与Fgf10和Tbx4相互作用调控蝾螈后肢芽外突的新功能 | Tozawa, S. | N/A | Novel function of Hox13 in regulating outgrowth of the newt hindlimb bud through interaction with Fgf10 and Tbx4 | |
| 及时的神经发生能够促进神经元分层过程中核包装顺序的增加 | Ferme, L. C. | N/A | Timely neurogenesis enables increased nuclear packing order during neuronal lamination | |
| Sox9和Nfi转录因子调控多巴胺前体细胞中神经发生和室管膜成熟的时机 | Lahti, L. | N/A | Sox9 and Nfi transcription factors regulate the timing of neurogenesis and ependymal maturation in dopamine progenitors | |
| Koolen-de Vries综合征的致病基因KANSL1对于运动纤毛的生成是必需的。 | Schmidt, J. D. | N/A | Koolen-de Vries Syndrome causal gene KANSL1 is required for motile ciliogenesis | |
| 利用机器智能进行回溯性运动分析，预测情绪障碍的潜在风险 | Jung, W. | N/A | Back-to-the-future motion analysis using machine intelligence predicts the potential risk of mood disorders | |
| 黑猩猩手势序列中下一个元素的可预测性 | Mielke, A. | N/A | Predictability of next elements in chimpanzee gesture sequences | |
| 刺激的不确定性和相对奖励率决定了感知决策中的适应性反应 | de la Cuesta-Ferrer, L. | N/A | Stimulus uncertainty and relative reward rates determine adaptive responding in perceptual decision-making | |
| 在乳腺癌诱导骨痛的小鼠模型中，数字通风笼（Digital Ventilated Cages）内的轮跑活动受损，而家庭笼内的活动未受影响。 | Hopkins, C. | N/A | Wheel running, but not home cage activity in Digital Ventilated Cages(R) is impaired in a mouse model of breast cancer-induced bone pain | |
| 慢性口服尼古丁对年轻成年早老素-1/2双敲除痴呆模型小鼠的嗅觉功能障碍无改善作用 | Si, Y. | N/A | Lack of Ameliorative Effect of Chronic Oral Nicotine on Olfactory Dysfunction in Young Adult Presenilin-1/2 Double Knockout Mice of a Dementia Model | |
| 增强牛磺酸摄取的牛磺酸转运蛋白的结构基础缓解细胞衰老 | Zhang, H. | N/A | Structural basis of augment taurine uptake by taurine transporter alleviating cellular senescence | |
| 注意你的光谱：验证同量异位组蛋白肽段形式鉴定时需要注意的要点 | Hijazi, H. | N/A | Mind Your Spectra: Points to be Aware of when Validating the Identification of Isobaric Histone Peptidoforms | |
| 使用表达植酸酶的酿酒酵母减少高粱面团中的抗营养因子植酸 | Kale, T. | N/A | Reducing phytate, an antinutritional factor, in sorghum dough using phytase-expressing Saccharomyces cerevisiae | |
| 在长达五亿年的进化过程中，顺式调控密码的保守性 | Ogawa, Y. | N/A | Conservation of cis-regulatory codes over half a billion years of evolution | |
| 驯化对犬科动物中新氨基酸改变突变的选择效应的进化影响 | G. Amorim, C. E. | N/A | Evolutionary consequences of domestication on the selective effects of new amino acid changing mutations in canids | |
| 一个多组织发育基因表达图谱，旨在理解绵羊表型的生物学基础 | Zhao, B. | N/A | A multi-tissue developmental gene expression atlas towards understanding the biological basis of phenotypes in sheep | |
| 人类基因组的调控可塑性 | Srivastava, J. | N/A | Regulatory plasticity of the human genome | |
| # BioRxiv 2024-11-13 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 药物抗性感染的机械时空模型 | Lee, T. E. | N/A | A mechanistic spatiotemporal model for drug resistant infections | |
| 普通豆（Phaseolus vulgaris L.）对土壤干燥的全株蒸腾响应：水通道蛋白与转录因子 | Cordoba-Novoa, H. A. | N/A | Whole Plant Transpiration Responses of Common Bean (Phaseolus vulgaris L.) to Drying Soil: Water Channels and Transcription Factors | |
| 为什么作物多模型研究中存在如此大的差异性？ | Wallach, D. | N/A | Why is there so much variability in crop multi-model studies? | |
| 克隆进化介导了KMT2A重排白血病中的Menin抑制剂耐药性。 | Mahdavi, L. | N/A | Clonal evolution mediates Menin-inhibitor resistance in KMT2A-rearranged leukemias. | |
| 心脏转录增强子在再生过程中被重新利用，以激活一种抗增殖程序 | Rao, A. | N/A | A Cardiac Transcriptional Enhancer is Repurposed During Regeneration to Activate an Anti-proliferative Program | |
| SNP分配用于估计遗传力（SAFE-h2）：一种探索表型基因组起源的工具，用于使用仅加性等位基因效应或加性和非加性等位基因效应估计SNP遗传力 | Darbani, B. | N/A | SNP Allocation For Estimating Heritability (SAFE-h2): A tool to explore genomic origins of phenotypes for estimation of SNP heritability using additive-only allelic effects or additive and non-additive allelic effects | |
| 炎症诱导的Claudin-2上调通过增强紧密连接调控的胰管运输来限制胰腺炎的进展。 | Kesaraju, S. | N/A | Inflammation-Induced Claudin-2 Upregulation Limits Pancreatitis Progression by Enhancing Tight Junction-Controlled Pancreatic Ductal Transport | |
| 展望未来：利用双翅目-沃尔巴克氏体系统的转录组元分析来预测虫媒病毒策略的可持续性 | Mejias, S. | N/A | A look into the the future: using a transcriptomic meta-analysis of Diptera-Wolbachia systems to project sustainability of arboviral strategies | |
| 腭部结构对中面部前后向生长的贡献 | Welsh, I. C. | N/A | Palatal segment contributions to midfacial anterior-posterior growth | |
| TreePPL：一种适用于系统发育学的通用概率编程语言 | Senderov, V. E. | N/A | TreePPL: A Universal Probabilistic Programming Language for Phylogenetics | |
| 组合CRISPR筛选揭示FYN和KDM4为治疗三阴性乳腺癌的协同药物组合靶点 | Kim, T. | N/A | Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer | |
| 通过基于结构稳定性的筛选，利用易于获取的人工同源序列实现蛋白质结构的高精度预测 | Tang, J. | N/A | Effective High-Accuracy Prediction of Protein Structures from Easily Obtainable Artificial Homologous Sequences by Structure-Stability-Based Selection | |
| 伊朗-安纳托利亚和高加索生物多样性热点地区的进化动力学：石竹科（Caryophyllaceae）中石竹属（Gypsophila）的进化辐射及其驱动因素 | Madhani, H. | N/A | Evolutionary dynamics in Irano-Anatolian and Caucasus biodiversity hotspots: Evolutionary radiation and its drivers in Gypsophila (Caryophyllaceae) | |
| 选择解释而非性能：基于机器学习的从脑连接预测人类智力的洞察 | Thiele, J. A. | N/A | Choosing explanation over performance: Insights from machine learning-based prediction of human intelligence from brain connectivity | |
| 将梯度提升树应用于QTL定位，并结合Shapley加性解释 | Ishibashi, T. | N/A | Applying gradient tree boosting to QTL mapping with Shapley additive explanations | |
| 学习到的反应动力学反映了刺激的时序，并在小鼠初级视觉皮层（V1）的浅层编码了时间预期的违反。 | Knudstrup, S. G. | N/A | Learned response dynamics reflect stimulus timing and encode temporal expectation violations in superficial layers of mouse V1 | |
| BiaPy：生物图像上的可访问深度学习 | Franco-Barranco, D. | N/A | BiaPy: Accessible deep learning on bioimages | |
| 致关节炎小鼠中致病性Th17细胞的TCR谱系向Treg样谱系偏移 | Llamas-Covarrubias, M. A. | N/A | The TCRs of pathogenic Th17 cells in arthritogenic mice are shifted toward a Treg-like repertoire | |
| 精细尺度的海洋学过程塑造了加拉帕戈斯群岛的海洋生物多样性模式。 | Holman, L. E. | N/A | Fine-scale oceanographic processes shape marine biodiversity patterns in the Galapagos Islands | |
| Celldetective：一款利用人工智能增强的图像分析工具，用于揭示动态细胞相互作用 | Torro, R. | N/A | Celldetective: an AI-enhanced image analysis tool for unraveling dynamic cell interactions | |
| 自然行为的视觉运动协调的低维表示 | Keshava, A. | N/A | Low-Dimensional Representations of Visuomotor Coordination for Natural Behavior | |
| 凝聚素IDC、H4K20me1及核周锚定维持秀丽隐杆线虫X染色体的抑制状态 | Trombley, J. | N/A | Condensin IDC, H4K20me1, and perinuclear tethering maintain X chromosome repression in C. elegans | |
| 果蝇的背侧扇形体是一个神经化学成分异质的睡眠调节中心。 | Jones, J. D. | N/A | The dorsal fan-shaped body is a neurochemically heterogeneous sleep-regulating center in Drosophila | |
| 化学遗传学刺激膈肌运动输出和膈肌活动 | Benevides, E. S. | N/A | Chemogenetic stimulation of phrenic motor output and diaphragm activity | |
| 5-HT1A受体在斑马鱼对潜在威胁的反应及社交性中的作用 | de Sousa, L. V. X. B. | N/A | Roles of the 5-HT1A receptor in zebrafish responses to potential threat and in sociality | |
| 利用贝叶斯参数估计与条件变分自编码器识别肌肉中的机制与治疗靶点 | Tune, T. C. | N/A | Identifying mechanisms and therapeutic targets in muscle using Bayesian parameter estimation with conditional variational autoencoders | |
| 在口头叙事理解中，大脑状态动态的三部分组织 | Liu, L. | N/A | Tripartite organization of brain state dynamics underlying spoken narrative comprehension | |
| 基于脑电图的连续语音包络重构的语音接收阈值估计 | Borges, H. B. | N/A | Speech-reception-threshold estimation via EEG-based continuous speech envelope reconstruction | |
| 空转：缺乏线粒体DNA的线粒体表现出差异化的运动性和连接性 | Chustecki, J. M. | N/A | Running on empty: Mitochondria without mtDNA exhibit differential motility and connectivity | |
| 微生物种群几乎从未以逻辑斯蒂方式增长，也从未以亚线性方式增长。 | Camacho-Mateu, J. | N/A | Microbial populations hardly ever grow logistically and never sublinearly | |
| 限时进食对饮食诱导的肥胖大鼠提供了有限的微胶质免疫代谢改善 | Jiao, H. | N/A | Time-restricted feeding provides limited microglial immunometabolic improvements in diet-induced obese rats | |
| 情感背景影响有蹄类动物的声纹特征 | Osiecka, A. N. | N/A | Emotional contexts influence vocal individuality in ungulates | |
| 一个用于筛选巨噬细胞外消化脂蛋白聚集体调节剂的高内涵显微镜药物筛选平台 | Ma, C.-I. J. | N/A | A high-content microscopy drug screening platform for regulators of the extracellular digestion of lipoprotein aggregates by macrophages | |
| 基于模拟的TMEM16家族调查显示，强健的脂质翻转需要一个开放的沟槽 | Stephens, C. A. | N/A | Simulation-based survey of TMEM16 family reveals that robust lipid scrambling requires an open groove | |
| 利用二维和三维图像分析工具对成年小鼠脑样本中微胶质细胞形态复杂性进行的比较研究 | Murray, C. J. | N/A | A comparison of microglial morphological complexity in adult mouse brain samples using 2-dimensional and 3-dimensional image analysis tools | |
| BAK驱动的凋亡孔形成的脂质特征 | Uren, R. T. | N/A | A lipid signature of BAK-driven apoptotic pore formation | |
| 针对铜绿假单胞菌III型分泌系统PcrV组分的抗人单克隆抗体通过不同的机制发挥中和作用 | Desveaux, J.-M. | N/A | Neutralizing human monoclonal antibodies that target the PcrV component of the Type III Secretion System of Pseudomonas aeruginosa act through distinct mechanisms | |
| 冷冻区动力学的数学建模：向在冷冻疗法中使用热成像仪迈进 | Ivakhnenko, O. V. | N/A | Mathematical modeling of the frozen zone dynamics: towards using thermal imagers in cryotherapy | |
| RSV基因组中的G-四链体：潜在的抗病毒靶点。 | Bose, D. | N/A | G-quadruplexes in the RSV genome: potential anti-viral targets. | |
| 背内侧纹状体中的神经炎症通过破坏稳态星形胶质细胞功能，导致目标导向行为控制过度。 | Abiero, A. R. | N/A | Neuroinflammation in the dorsomedial striatum causes excessive goal-directed action control by disrupting homeostatic astrocyte function | |
| 斑马鱼中个体保守神经元微外显子及其主调控因子的表型影响 | Lopez-Blanch, L. | N/A | Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish | |
| FoldMark：通过水印保护蛋白质生成模型 | ZHANG, Z. | N/A | FoldMark: Protecting Protein Generative Models with Watermarking | |
| 评估人类祖先颅牙特征的系统发育信息含量和冗余性 | Raskin, L. Y. | N/A | Assessing phylogenetic information content and redundancy in hominin craniodental traits | |
| Aramchol减轻了小鼠胆道纤维化模型中的纤维化，并阻断了TGFβ诱导的胆管细胞中的纤维炎症介质。 | Aseem, S. O. | N/A | Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes | |
| 人类行为中逐次试验学习后继表征 | Kahn, A. E. | N/A | Trial-by-trial learning of successor representations in human behavior | |
| 基于捕获离子迁移支持的MALDI MS/MS成像的空间蛋白质组学：多重和空间肽鉴定的初步观察 | Li, M. J. | N/A | Spatial Proteomics by Trapped Ion Mobility supported MALDI MS/MS Imaging: A First Glance into Multiplexed and Spatial Peptide Identification | |
| 夜行土豚（Orycteropus afer，管齿目）的眼部特征与视网膜光感受器 | Peichl, L. | N/A | Eye features and retinal photoreceptors of the nocturnal aardvark (Orycteropus afer, Tubulidentata) | |
| 跨平台DNA基序发现与基准测试：探索研究不足的人类转录因子结合特异性 | Vorontsov, I. E. | N/A | Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors | |
| ER Ca2+水平通过调节STIM1和L型Ca2+通道活性来控制神经调质的分泌。 | Hoogstraaten, R. I. | N/A | ER Ca2+-levels control neuromodulator secretion by regulating STIM1 and L-type Ca2+-channel activity | |
| 溶酶体自主调节髓系细胞状态和免疫反应 | Tejwani, L. | N/A | Lysosomes cell autonomously regulate myeloid cell states and immune responses | |
| 空间限制诱导表皮角质形成细胞的往复迁移，并形成三相上皮 | Nohara, T. | N/A | Spatial confinement induces reciprocating migration of epidermal keratinocytes and forms triphasic epithelia | |
| 在小鼠下呼吸道中进行靶向预处理和细胞移植 | Kohn, A. | N/A | Targeted pre-conditioning and cell transplantation in the murine lower respiratory tract | |
| TMEM55B的丢失通过失调的脂噬作用和线粒体功能调节脂质代谢 | Qin, Y. | N/A | Loss of TMEM55B modulates lipid metabolism through dysregulated lipophagy and mitochondrial function | |
| CEP152与PLK4的结合刺激了激酶活性，从而促进中心粒的组装。 | Hoffmann, I. | N/A | Binding of CEP152 to PLK4 stimulates kinase activity to promote centriole assembly | |
| 信号素4A维持造血干细胞池的功能多样性 | Toghani, D. | N/A | Semaphorin 4A maintains functional diversity of the hematopoietic stem cell pool | |
| βTrCP1的过度表达可诱导顺铂诱导的衰老细胞发生细胞死亡。 | Belmonte-Fernandez, A. | N/A | Overexpression of betaTrCP1 elicits cell death in cisplatin-induced senescent cells | |
| 一种与Rett综合征相关的KCNC1变异体破坏了Kv3.1通道从内质网到高尔基体的运输 | Maureira, D. | N/A | A KCNC1 Variant Linked to Rett Syndrome Disrupts ER to Golgi Trafficking of Kv3.1 Channel | |
| NG497对脂肪甘油三酯脂肪酶的急性抑制作用扰乱了人胰岛中胰岛素和胰高血糖素的分泌 | Kim, L. | N/A | Acute Inhibition of Adipose Triglyceride Lipase by NG497 Dysregulates Insulin and Glucagon Secretion from Human Islets | |
| 从在线模式回归线下生物化学顶点实验室：从新冠疫情在线教学模式中汲取的经验教训，以提升基于课程的本科生科研体验 | Rascon, A. A. | N/A | Pivoting Back to the In-Person Capstone Biochemistry Lab: Lessons Learned from the COVID-19 Online Modality to Improve the Course-based Undergraduate Research Experience | |
| 评估生成式人工智能在环境研究科学传播中的质量 | Worden, D. | N/A | Assessing the quality of generative artificial intelligence for science communication in environmental research | |
| 在捕食飞行过程中，蜻蜓目标探测神经元的无线记录 | Lin, H.-T. | N/A | Wireless recordings from dragonfly target detecting neurons during prey interception flight | |
| 慢性可变轻度应激以性别依赖的方式改变了终纹床核前背侧核的转录组和信号传导特性 | Degroat, T. J. | N/A | Chronic variable mild stress alters the transcriptome and signaling properties of the anterodorsal bed nuceleus of the stria terminalis in a sex-dependent manner | |
| 利用蛋白质组学分析和配体结合实验探索神经退行性疾病的新型生物标志物 | Kenzelmann, A. | N/A | Exploration of novel biomarkers for neurodegenerative diseases using proteomic analysis and ligand-binding assays | |
| 非临床和临床环境中的优柔寡断与近期加权证据整合 | del Rio, M. | N/A | Indecision and recency-weighted evidence integration in non-clinical and clinical settings | |
| 血清代谢组学分析显示，轻度认知障碍患者在脂质代谢方面存在性别差异。 | Diaz Escarcega, R. | N/A | Serum metabolome profiling in patients with mild cognitive impairment reveals sex differences in lipid metabolism | |
| 用于检测盐杆菌慢性感染病毒的优化噬菌斑检测法 | Navok, S. | N/A | Optimized Plaque Assay for Detecting Chronically Infecting Viruses of Haloarchaea | |
| 坏死性凋亡向凋亡信号轴是炎症性肠病的基础 | Pang, J. | N/A | A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease | |
| 异染色质表观突变通过引发线粒体功能障碍，从而赋予抗真菌抵抗力。 | Fellas, A. | N/A | Heterochromatin epimutations impose mitochondrial dysfunction to confer antifungal resistance | |
| 三种全球大肠杆菌转录调节因子的适应性景观 | Antunes Westmann, C. | N/A | The adaptive landscapes of three global Escherichia coli transcriptional regulators | |
| 温室马铃薯蚜虫（Aulacorthum solani）的初步基因组序列 | Torres, J. | N/A | Draft genome sequence of the glasshouse-potato aphid Aulacorthum solani | |
| invertiaDB：一个跨物种基因组倒位重复数据库 | Provatas, K. | N/A | invertiaDB: A Database of Inverted Repeats Across Organismal Genomes | |
| 多细胞整体控制器代谢负担效应的计算机模拟分析 | Campanile, G. | N/A | In silico analysis of metabolic burden effects on a multicellular integral controller | |
| 多模态状态依赖性连接分析：脑干和基底前脑中的觉醒与自主神经中枢 | Pourmotabbed, H. | N/A | Multimodal state-dependent connectivity analysis of arousal and autonomic centers in the brainstem and basal forebrain | |
| Srs2/PARI DNA解旋酶介导了酵母和人细胞中染色质桥响应的细胞分离抑制 | Dam, M. | N/A | Srs2/PARI DNA helicase mediates abscission inhibition in response to chromatin bridges in yeast and human cells | |
| 城市共居景观：在ECOLOPES框架下探索欧洲共居土地景观的多样性。 | Oneto, G. | N/A | Urban Cohabscapes: exploring European Co-Habitative landScapes diversity, in the ECOLOPES framework. | |
| 通过mRNA实现人类皮肤再生 | Li, L. | N/A | Human skin rejuvenation via mRNA | |
| 结合细胞学和蛋白质组学的方法表明，海绵Halichondria panicea对本地和外来弧菌的处理存在差异。 | Marulanda-Gomez, A. M. | N/A | Combined cellular and proteomics approach suggest differential processing of native and foreign vibrios in the sponge Halichondria panicea | |
| 不同SARS-CoV-2病毒变种（武汉株、Delta株、Omicron株）在模型动物器官中积累的比较特征 | Chernov, A. | N/A | COMPARATIVE CHARACTERISTICS OF THE ACCUMULATION OF DIFFERENT VARIANTS OF THE SARS-COV-2 VIRUS (WUHAN, DELTA, OMICRON) IN THE ORGANS OF MODEL ANIMALS | |
| 一种伴侣蛋白复合物调控疟原虫细胞器的蛋白质稳态 | Tissawak, A. | N/A | A Chaperonin Complex Regulates Organelle Proteostasis in Malaria Parasites | |
| 植物病原菌红球菌中发现利迪霉素A生物合成基因簇，指导结构修正和分子靶点鉴定 | Ford, J. J. | N/A | Discovery of lydiamycin A biosynthetic gene cluster in the plant pathogen Rhodococcus fascians guides structural revision and identification of molecular target | |
| SARS-CoV-2 EndoU核糖核酸酶调控RNA重组并影响病毒适应性。 | Zhou, Y. | N/A | SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitness. | |
| 大肠杆菌K12中tRNA修饰缺陷的协同效应。 | Bacusmo, J. o. M. | N/A | Synergistic effects of tRNA modification defects in Escherichia coli K12. | |
| 同时考虑选择和微生物生成计数，为理解全生物体的进化和生态动态提供了独特的见解。 | Pearman, W. S. | N/A | Joint consideration of selection and microbial generation count provides unique insights into evolutionary and ecological dynamics of holobionts | |
| 霍乱弧菌的谱系和泛基因组多样性在孟加拉国一年内呈现出地理上的变化。 | Qin, C. | N/A | Vibrio cholerae lineage and pangenome diversity varies geographically across Bangladesh over one year | |
| 最近SARS-CoV-2变种被pemivibart谱系中基因和结构相关的单克隆抗体中和 | Powers, C. | N/A | Neutralization of recent SARS-CoV-2 variants by genetically and structurally related mAbs of the pemivibart lineage | |
| 基于造血干细胞的抗HIV-1基因疗法，配备安全终止开关，以防御和攻击HIV-1感染 | Guo, Q. | N/A | Anti-HIV-1 HSPC-based gene therapy with safety kill switch to defend against and attack HIV-1 infection | |
| 探究intimin/invasin在嗜水气单胞菌（Aeromonas hydrophila）对露比鱼（Labeo rohita）致病性中的潜在作用：宿主-微生物相互作用研究 | Bhattacharyya, A. | N/A | Investigating the potential role of intimin/invasin in Aeromonas hydrophila virulence in Labeo rohita: a host-microbe interaction study | |
| 绘制按蚊雌蚊中疟原虫的转变与相互作用 | Yan, Y. | N/A | Mapping Plasmodium transitions and interactions in the Anopheles female | |
| 元蛋白质组学揭示了仓鼠感染SARS-CoV-2后肠道微生物组的年龄特异性改变 | Creskey, M. | N/A | Metaproteomics reveals age-specific alterations of gut microbiome in hamsters with SARS-CoV-2 infection | |
| 人类ClpXP的冷冻电镜结构揭示了其组装和蛋白水解激活的机制 | Chen, W. | N/A | Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation | |
| 寄生线虫单细胞核分离与RNA测序的优化 | Buddenborg, S. K. | N/A | Optimisation of single-nuclei isolation and RNA sequencing of parasitic nematodes | |
| 整合石莼功能基因组学：基因编辑与新型筛选系统 | Blomme, J. | N/A | Consolidating Ulva functional genomics: Gene editing and new selection systems | |
| 小分子抑制剂联合治疗能有效抑制弥漫性大B细胞淋巴瘤中的B细胞信号传导。 | Witmond, M. | N/A | Small molecule inhibitor combination treatment effectively represses global B-cell signaling in diffuse large B-cell lymphoma | |
| SARS-CoV-2 XEC变体的免疫逃逸、细胞融合及刺突蛋白稳定性：N端结构域糖基化突变的作用 | Li, P. | N/A | Immune Evasion, Cell-Cell Fusion, and Spike Stability of the SARS-CoV-2 XEC Variant: Role of Glycosylation Mutations at the N-terminal Domain | |
| 细菌乙酰转移酶PatZ的催化及变构机制的结构基础 | Park, J. B. | N/A | Structural basis of the catalytic and allosteric mechanism of bacterial acetyltransferase PatZ | |
| 病毒感染期间ATP分配的动态代谢建模 | Lu, A. | N/A | Dynamic metabolic modeling of ATP allocation during viral infection | |
| 端粒转座子广泛存在于线性细菌基因组中。 | Hsieh, S.-C. | N/A | Telomeric transposons are pervasive in linear bacterial genomes | |
| G蛋白偶联受体17通过Gi/o依赖机制抑制肠内分泌细胞中胰高血糖素样肽-1的分泌 | Conley, J. M. | N/A | G protein-coupled receptor 17 inhibits glucagon-like peptide-1 secretion via a Gi/o-dependent mechanism in enteroendocrine cells | |
| 有丝分裂中的CIP2A-TOPBP1轴促进MiDAS与MMEJ之间的有丝分裂途径选择。 | Martin, P. R. | N/A | The mitotic CIP2A-TOPBP1 axis facilitates mitotic pathway choice between MiDAS and MMEJ | |
| 由细菌微区室封装肽驱动的生物分子凝聚的蓝图 | Trettel, D. | N/A | A blueprint for biomolecular condensation driven by bacterial microcompartment encapsulation peptides | |
| 在不确定性下的遗传电路风险规避优化 | Kobiela, M. | N/A | Risk-averse optimization of genetic circuits under uncertainty | |
| # BioRxiv 2024-11-12 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 泛素介导的人类26S蛋白酶体在底物降解过程中的自调节隐藏动力学 | Wu, Z. | N/A | Hidden dynamics of ubiquitin-mediated autoregulation of human 26S proteasome during substrate degradation | |
| 多重连接组轨迹使得多种连接模式能够并行实现。 | Mostame, P. | N/A | A multiplex of connectome trajectories enables several connectivity patterns in parallel | |
| 增强突变热点预测：原子波动的作用 | Martis, E. A. F. | N/A | Enhancing Mutational Hotspot Predictions: The Role of Atomic Fluctuations | |
| 肌动蛋白失调引发神经内分泌可塑性和免疫逃逸：小细胞肺癌的一个脆弱性 | Seo, Y. | N/A | Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer | |
| 增强轴向光学镊子的应用力和作用范围 | Milstein, J. N. | N/A | Enhancing the Applied Force and Range of Axial Optical Tweezers | |
| 撤销：钢琴演奏中认知与情感相互影响的神经生理学 | Higuchi, M. K. K. | N/A | WITHDRAWN: Neurophysiology of Reciprocal Influence of Cognition and Emotion in Pianistic Performances | |
| 阿尔茨海默病中性别依赖性脆弱性的原因：后扣带皮层中受损的Parvalbumin中间神经元 | Terstege, D. J. | N/A | Impaired parvalbumin interneurons in the retrosplenial cortex as the cause of sex-dependent vulnerability in Alzheimer's disease | |
| NOTCH1的表达状态转变伴随着人类早期视网膜祖细胞中的染色质重塑 | Watabe, Y. | N/A | Expression status transition of NOTCH1 accompanies chromatin remodeling in human early retinal progenitor cells | |
| 探究数学学习困难儿童的前顶叶网络及激活情况：不同缺陷特征的案例研究 | Wang, F. | N/A | Investigating Frontoparietal Networks and Activation in Children with Mathematics Learning Difficulties: Cases with Different Deficit Profiles | |
| scEGOT：基于熵高斯混合最优传输的单细胞轨迹推断框架 | Yachimura, T. | N/A | scEGOT: Single-cell trajectory inference framework based on entropic Gaussian mixture optimal transport | |
| 物种特性和群落结构可以推动生态系统中大规模的空间效应传播。 | Garcia-Callejas, D. | N/A | Species traits and community structure can drive large-scale spatial propagation of effects in ecosystems | |
| 基于模型的突触可塑性规则推断 | Mehta, Y. | N/A | Model Based Inference of Synaptic Plasticity Rules | |
| 室管膜下区神经胶质生成调节脑缺血后胶质瘢痕处的细胞外基质 | Ardaya, M. | N/A | Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia | |
| 靶向缺氧人乳腺癌干细胞的分子货物胞内递送 | Makela, A. V. | N/A | Targeted intracellular delivery of molecular cargo to hypoxic human breast cancer stem cells | |
| 将残基级蛋白质语言模型嵌入与最优传输相结合 | NaderiAlizadeh, N. | N/A | Aggregating Residue-Level Protein Language Model Embeddings with Optimal Transport | |
| 驯化的转座子蛋白L1TD1与其祖先L1 ORF1p相互作用，促进LINE-1逆转录转座 | Kavaklioglu, G. | N/A | The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition | |
| 基于相关自然统计的高效编码解释的重量错觉 | Bays, P. | N/A | Weight illusions explained by efficient coding based on correlated natural statistics | |
| 受损的26S蛋白酶体导致小鼠学习和记忆缺陷，并诱导由NF-κB介导的神经炎症 | Huber, C. | N/A | Impaired 26S proteasome causes learning and memory deficiency and induces neuroinflammation mediated by NF-κB in mice | |
| 棕色藻类作为沿海生态系统关键组成部分的进化基因组学研究 | Denoeud, F. | N/A | Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems | |
| 机械负荷揭示了在小鼠心脏代谢疾病中，心肌细胞固有的刚度对舒张功能障碍的贡献。 | Janssens, J. V. | N/A | Mechanical loading reveals an intrinsic cardiomyocyte stiffness contribution to diastolic dysfunction in murine cardiometabolic disease | |
| 皮质丘脑模型在睡眠神经生理学中的应用及其在移动脑电图中的应用 | Morshedzadeh, T. | N/A | Corticothalamic modelling of sleep neurophysiology with applications to mobile EEG | |
| 单细胞RNA测序揭示了不同关系间的转录同步性 | Brusman, L. E. | N/A | Single nucleus RNA-sequencing reveals transcriptional synchrony across different relationships | |
| 一种涉及巨型可移动元件的古老倒位多态性在入侵性真菌病原体中 | Hartmann, F. E. | N/A | An old inversion polymorphism involving giant mobile elements in an invasive fungal pathogen | |
| 在喜马拉雅山西部，尺蛾科蛾类群落的特征分布并不随海拔梯度变化。 | Dey, P. | N/A | Trait distribution in Geometrid moth assemblages does not vary along a western Himalayan elevational gradient | |
| 一种涉及多个P450基因的基因组重复有助于登革热蚊子埃及伊蚊的杀虫剂抗性。 | Bacot, T. | N/A | A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti | |
| 单细胞RNA测序（scRNA-seq）和单细胞ATAC测序（scATAC-seq）揭示了支持细胞通过阶段特异性通信在非阻塞性无精症中调节精子发生障碍 | Wang, S. | N/A | ScRNA-seq and scATAC-seq reveal that sertoli cell mediate spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia | |
| 在生物物理上真实的兴奋-抑制尖峰网络中进行高效编码 | Koren, V. | N/A | Efficient coding in biophysically realistic excitatory-inhibitory spiking networks | |
| 多价Afadin相互作用促进IDR介导的凝聚体形成和上皮细胞的连接分离 | Kuno, S. | N/A | Multivalent Afadin Interaction Promotes IDR-Mediated Condensate Formation and Junctional Separation of Epithelial Cells | |
| 脑膜调节性T细胞衍生的脑啡肽调控痛觉 | Midavaine, E. | N/A | Meningeal Regulatory T cell-derived enkephalin gates nociception | |
| 非巢友歧视在蚂蚁中起到排除社会性寄生同种个体的作用 | Nakamura, T. P. | N/A | Discrimination against non-nestmates functions to exclude socially parasitic conspecifics in an ant | |
| 白细胞介素-1通过诱导肌动蛋白束的形成，阻止了SARS-CoV-2诱导的膜融合，从而限制了病毒的传播。 | Zheng, X. | N/A | Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles | |
| fmo-4通过ER到线粒体的钙调节在秀丽隐杆线虫中促进长寿和应激抗性 | Tuckowski, A. M. | N/A | fmo-4 promotes longevity and stress resistance via ER to mitochondria calcium regulation in C. elegans | |
| 热带珊瑚礁鱼类的比较宏基因组学研究表明，尽管宿主和饮食各异，但其肠道核心功能高度保守，同时存在与饮食相关的功能基因富集现象。 | Wu, D. G. | N/A | Comparative metagenomics of tropical reef fishes show conserved core gut functions across hosts and diets with diet-related functional gene enrichments | |
| 毒力进化：跳出宿主的思维框架 | Silva, L. M. | N/A | Virulence evolution: thinking outside of the host | |
| 胰腺癌细胞通过隧道纳米管交换核糖体 | Martinkova, S. | N/A | Pancreatic cancer cells exchange ribosomes through tunneling nanotubes | |
| 在裂顎目（sclerosomatid Opiliones）中，婚配礼物的减少与行为性冲突的增加相吻合。 | Brown, T. A. | N/A | The reduction of nuptial gifts in sclerosomatid Opiliones coincides with increased behavioural sexual conflict | |
| 细胞信号：多模态与情境化机器学习基础在治疗学中的应用 | Velez-Arce, A. | N/A | Signals in the Cells: Multimodal and Contextualized Machine Learning Foundations for Therapeutics | |
| 系统建模揭示了ME/CFS和长期新冠肺炎中共同的代谢失调及新型治疗方法 | Li, G.-H. | N/A | Systems Modeling Reveals Shared Metabolic Dysregulation and Novel Therapeutic Treatments in ME/CFS and Long COVID | |
| 脂肪体衍生细胞因子Upd2调控果蝇气管干细胞的有序迁移 | Dong, P. | N/A | Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila | |
| 更快速的基于模型的祖先比例估计 | Santander, C. | N/A | Faster model-based estimation of ancestry proportions | |
| 可移动元件积累推动南美洲刺蛾物种Hylesia metabus（鳞翅目：天蚕蛾科）基因组大小增加 | Perrier, C. | N/A | Transposable element accumulation drives genome size increase in Hylesia metabus (Lepidoptera: Saturniidae), an urticating moth species from South America | |
| 人类大脑祖先条形码 | Shibata, D. | N/A | Human Brain Ancestral Barcodes | |
| 鉴定用于神经退行性疾病治疗的新型小分子伴侣激活剂 | Ho, A. | N/A | Identification of novel small molecule chaperone activators for neurodegenerative disease treatment | |
| 经济高效的DNA存储技术：DNA活字印刷术 | Wang, C. | N/A | Cost-effective DNA storage with DNA movable type | |
| PINK1的缺失会导致黑质纹状体多巴胺能神经元中依赖年龄的线粒体运输缺陷，这是由于p38 MAPK的异常激活所致。 | Zhao, J. | N/A | Loss of PINK1 causes age-dependent mitochondrial trafficking deficits in nigrostriatal dopaminergic neurons through aberrant activation of p38 MAPK | |
| 照亮微生物席的组装：蓝细菌和绿屈挠菌门合作构建光响应生物膜 | Bunbury, F. | N/A | Illuminating microbial mat assembly: Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms | |
| 外毛细胞搅动耳蜗内的液体。 | Lee, C. | N/A | Outer hair cells stir cochlear fluids | |
| Nup107是果蝇（Drosophila melanogaster）中Torso介导的变态转变的关键调控因子。 | Kawadkar, J. | N/A | Nup107 is a crucial regulator of Torso-mediated metamorphic transition in Drosophila melanogaster | |
| 在斑马鱼胚胎的自发神经活动中，出生顺序指定了运动回路的招募 | Abi Younes, M. | N/A | Birth order specified recruitment of motor circuits during spontaneous neural activity in zebrafish embryo | |
| NEBULA101：一个用于研究语言能力在行为、大脑结构和功能方面的开放数据集 | Rampinini, A. C. | N/A | NEBULA101: an open dataset for the study of language aptitude in behaviour, brain structure and function | |
| Inpp5e 对光感受器外节维护至关重要 | Gupta, M. | N/A | Inpp5e Is Critical for Photoreceptor Outer Segment Maintenance | |
| 基于秀丽隐杆线虫毒性测试的自动化微流控平台 | Wu, J. | N/A | An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans | |
| 结构导向的瘿形成微生物分泌组分析提供了对效应子多样性和进化的见解 | Mukhopadhyay, S. | N/A | Structure-guided secretome analysis of gall-forming microbes offers insights into effector diversity and evolution | |
| 负电荷，而非必需的磷酸化，是14-3-3蛋白配体识别所必需的 | Kamayirese, S. | N/A | Negative Charges, Not Necessary Phosphorylation, are Required for Ligand Recognition by 14-3-3 Proteins | |
| 尼安德特人衍生的变异影响人类疾病位点的颅面增强子活性 | Uttley, K. | N/A | Neanderthal-derived variants shape craniofacial enhancer activity at a human disease locus | |
| 在右美托咪定诱导意识丧失期间大脑连接性和神经血管动力学的变化 | Fotiadis, P. | N/A | Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness | |
| 在观察动作时，空间信息和解剖信息的处理具有不同的时序 | Waltzing, B. M. | N/A | Separate timescales for spatial and anatomical information processing during action observation | |
| 成年大鼠的多重情境辨别：性别差异与厌恶记忆的时间依赖性泛化动态 | Alves, F. N. L. | N/A | Multiple context discrimination in adult rats: sex variability and dynamics of time-dependent generalization of an aversive memory | |
| APOE基因型和生物年龄影响与生物能量代谢相关的多组学关联 | Ellis, D. S. | N/A | APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics | |
| 中间普雷沃菌的蛋白酶interpain A促进人舌鳞状细胞癌细胞增殖和迁移 | Chang, S.-M. | N/A | The protease interpain A of Prevotella intermedia promotes human OSCC cells proliferation and migration | |
| 早衰症中层粘连蛋白的相行为与解离动力学：聚合物模型研究 | Hameed, H. A. | N/A | Phase Behavior and Dissociation Kinetics of Lamins in a Polymer Model of Progeria | |
| Metagenomics-Toolkit：灵活高效的基于云的宏基因组学工作流程，具备机器学习驱动的资源分配功能 | Belmann, P. | N/A | Metagenomics-Toolkit: The Flexible and Efficient Cloud-Based Metagenomics Workflow featuring Machine Learning-Enabled Resource Allocation | |
| Gb3三糖基化外泌体作为志贺毒素1型的新型中和剂 | Mikolajczyk, K. | N/A | Gb3 trisaccharide-bearing exosomes as a novel neutralizer for Shiga toxin type 1 | |
| CD90识别出具有不同激活和静息维持模式的肌肉干细胞的不同亚群 | Kheir, E. | N/A | CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance | |
| 全面的蛋白质组学特征描述了高尔基体内运输中间体 | Sumya, F. T. | N/A | Comprehensive Proteomic Characterization of Intra-Golgi Trafficking Intermediates | |
| 系统性炎症和淋巴细胞激活先于类风湿性关节炎 | He, Z. | N/A | Systemic inflammation and lymphocyte activation precede rheumatoid arthritis | |
| 利用改良的群体分离分析法鉴定出芽殖酵母铜抗性中的上位性和隐性数量性状位点 | Buzby, C. | N/A | Epistasis and cryptic QTL identified using modified bulk segregant analysis of copper resistance in budding yeast | |
| 时空转录组分析揭示了发育过程中分子梯度模式以及沿耳蜗轴的音调组织结构。 | Yan, M. | N/A | Spatiotemporal transcriptomic analyses reveal molecular gradient patterning during development and the tonotopic organization along cochlear axis | |
| 最佳竞争者：互利共生者（如传粉者）的吸引力与选择之间的平衡推动了促进作用，并可能促进作物传粉。 | Dornhaus, A. | N/A | Optimal competitors: the balance of attraction and choices of mutualists, like pollinators, drives facilitation and may promote crop pollination | |
| RBFOX1缺陷的纠正能够修复亨廷顿病的错误剪接并减轻病理 | Lozano-Munoz, D. | N/A | Correction of RBFOX1 deficit rescues Huntington's disease mis-splicing and pathology | |
| 丛枝菌根真菌基因型和核组织作为宿主植物营养获取和稳定碳捕获的驱动因素 | Ferguson, R. | N/A | Arbuscular mycorrhizal fungal genotype and nuclear organization as driving factors in host plant nutrient acquisition and stable carbon capture | |
| 加拿大科学研究生的津贴低于贫困线。 | Fraass, A. J. | N/A | Canadian science graduate stipends lie below the poverty line | |
| 使用荧光图像中的不均匀背景减除法进行即时早期基因表达神经元的自动细胞检测 | Osanai, H. | N/A | Automated cell detection for immediate early gene-expressing neurons using inhomogeneous background subtraction in fluorescent images | |
| 南非2024年猴痘分子流行病学初步报告 | Featherston, J. | N/A | Preliminary report on the molecular epidemiology of mpox, South Africa 2024 | |
| scLong：一种拥有十亿参数的基础模型，用于在单细胞转录组学中捕捉长程基因上下文 | Bai, D. | N/A | scLong: A Billion-Parameter Foundation Model for Capturing Long-Range Gene Context in Single-Cell Transcriptomics | |
| 以少求多：基于模拟的推断使扩散加权磁共振成像在极短的采集时间内实现高精度 | Eggl, M. F. | N/A | More with less: Simulation-based inference enables accurate diffusion-weighted MRI with minimal acquisition time | |
| 持续的感觉运动转换增强了猕猴运动皮层神经动力学对扰动的鲁棒性 | Zheng, C. | N/A | Continuous sensorimotor transformation enhances robustness of neural dynamics to perturbation in macaque motor cortex | |
| 扩展杏仁核促肾上腺皮质激素释放激素神经元调控草原田鼠（Microtus ochrogaster）在社会挫败后形成的配对结合中的性别二态性变化 | Tickerhoof, M. C. | N/A | Extended amygdala corticotropin-releasing hormone neurons regulate sexually dimorphic changes in pair bond formation following social defeat in prairie voles (Microtus ochrogaster) | |
| CircAge：一个综合性的跨物种和组织的老化相关环状RNA资源 | Dong, X. | N/A | CircAge: A Comprehensive Resource for Aging-Associated Circular RNAs Across Species and Tissues | |
| 整合知识、组学和人工智能，开发患者特异性的虚拟化身 | Bekkar, A. | N/A | Integrating knowledge, omics and AI to develop patient-specific virtual avatars | |
| 基于图自编码器和StrNN的心力衰竭患者死亡率因果分析 | Kim, D. | N/A | Graph Autoencoder and StrNN based Causal Analysis of Mortality in Heart Failure Patients | |
| 抑制富含丝氨酸和精氨酸的剪接因子3可诱导表皮分化并降低皮肤鳞状细胞癌风险 | Donohue, I. M. | N/A | Inhibition of serine and arginine-rich splicing factor 3 induces epidermal differentiation and decreases cutaneous squamous cell carcinoma risk | |
| TRPV4钙通透性通道有助于主动脉狭窄中的瓣膜硬化 | Dutta, B. | N/A | TRPV4 calcium-permeable channel contributes to valve stiffening in aortic stenosis | |
| 对大脑中非言语听觉记忆的系统性及元分析回顾 | Campo, F. F. | N/A | A systematic and meta-analytic review of non-verbal auditory memory in the brain | |
| 偏头痛与内感受之间的关系：准确性正常但感觉和行为改变 | Jones, S. | N/A | Relationships between migraine and interoception: normal accuracy but altered sensibility and behaviour | |
| 多结果生存数据的惩罚降秩回归支持年龄相关疾病的共同代谢风险评分 | Sluiskes, M. H. | N/A | Penalized reduced rank regression for multi-outcome survival data supports a common metabolic risk score for age-related diseases | |
| 用于跨物种测试膜定位标签的工具包 | Karapidaki, I. | N/A | A toolkit for testing membrane localisation tags across species | |
| 耦合人地系统建模趋势：范围综述 | Thampi, V. | N/A | Trends in Coupled Human-Environment Systems Modelling: A Scoping Review | |
| 传统草药提取物对抗多药耐药细菌的有效性：综述 | Pane, Y. S. | N/A | Effectiveness of Traditional Herbal Extracts Against Multidrug-Resistant Bacteria: A Review | |
| 海马体OLM中间神经元调节CA1位置细胞的可塑性和重映射 | Udakis, M. | N/A | Hippocampal OLM interneurons regulate CA1 place cell plasticity and remapping | |
| γ-分泌酶功能障碍谱作为PSEN1、PSEN2和APP致病基因中ADAD发病年龄的统一预测因子 | Gutierrez Fernandez, S. | N/A | Spectrum of gamma-Secretase dysfunction as a unifying predictor of ADAD age at onset across PSEN1, PSEN2 and APP causal genes | |
| 气候变化塑造了亚高山草地实验中的物种丰富度-均匀度关系 | Muehlbauer, L. K. | N/A | Climate change shapes richness-evenness relationships in a subalpine grassland experiment | |
| 个体间基因表达的变异性意味着大脑偏倚基因在各器官中具有稳定的调控机制。 | Bucao, C. F. | N/A | Inter-individual gene expression variability implies stable regulation of brain-biased genes across organs | |
| 系统性基因组-表观基因组分析揭示了胃肠道腺癌中与MYB相关的超级增强子的谱系特异性及功能意义 | Li, F. | N/A | Systemic genome-epigenome analysis captures the lineage specificity and functional significance for MYB associated super-enhancer in gastrointestinal adenocarcinoma | |
| GHT-SELEX 展示了许多人源转录因子出乎意料的高内在序列特异性及复杂的 DNA 结合特性。 | Jolma, A. | N/A | GHT-SELEX demonstrates unexpectedly high intrinsic sequence specificity and complex DNA binding of many human transcription factors | |
| 大量未知的人类转录因子与基因组暗物质结合 | Razavi, R. | N/A | Extensive binding of uncharacterized human transcription factors to genomic dark matter | |
| 一种综合方法用于优先筛选牛复杂性状的候选因果基因 | Ghoreishifar, M. | N/A | An integrative approach to prioritize candidate causal genes for complex traits in cattle | |
| gen3DNet：一个用于生成三维网络模型的R包 | Mollah, S. | N/A | gen3DNet: An R Package for Generating 3D Network Models | |
| scExplorer：一个全面的单细胞RNA测序数据分析网络服务器 | Galaz, S. F. H. | N/A | scExplorer: A Comprehensive Web Server for Single-Cell RNA Sequencing Data Analysis | |
| 虚拟实验室：AI智能体设计新型SARS-CoV-2纳米抗体并经实验验证 | Swanson, K. | N/A | The Virtual Lab: AI Agents Design New SARS-CoV-2 Nanobodies with Experimental Validation | |
| 一种计算上非结构化蛋白质的简单方法：一些发现 | Powell, A. | N/A | A simple method for computationally unstructuring proteins: some findings | |
| 单细胞多组学分析揭示了NPM1突变型AML克隆演化中的基因型-免疫表型关系 | Drucker, M. | N/A | Genotype-immunophenotype relationships in NPM1-mutant AML clonal evolution uncovered by single cell multiomic analysis | |
| 通过呼出气颗粒（PExA）收集的远端肺液态活检中的microRNA和非靶向蛋白质组分析揭示了细胞外囊泡的存在。 | Bonatti, M. | N/A | microRNA and non-targeted proteome analysis of liquid biopsies from the distal lung collected by Particles in Exhaled Air (PExA) reveals presence from extracellular vesicles | |
| 工程化和进化型自养大肠杆菌菌株的系统级表征 | Yilmaz, S. | N/A | System-level characterization of engineered and evolved formatotrophic E. coli strains | |
| 调控蛋白质在十种人类癌症类型中丰度的主调控因子 | Wang, Z. | N/A | Master regulators governing protein abundance across ten human cancer types | |
| DIA-BERT：用于增强DIA蛋白质组学数据分析的端到端预训练变换器模型 | Liu, Z. | N/A | DIA-BERT: pre-trained end-to-end transformer models for enhanced DIA proteomics data analysis | |
| 初级视觉皮层中运动的潜在编码 | Cosnier-Horeau, C. | N/A | Latent encoding of movement in primary visual cortex | |
| SIMPL：从行为中优化神经表征的扩展且简便的方法 | George, T. M. | N/A | SIMPL: Scalable and hassle-free optimization of neural representations from behaviour | |
| 尼莫地平在体外可减少小胶质细胞的激活，这一结论通过形态学表型、吞噬活性和新一代RNA测序得以证实。 | Pesti, I. | N/A | Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and next generation RNA sequencing | |
| 高级视觉皮层的组织与视觉信息而非抽象的语言信息相一致。 | Shoham, A. | N/A | The organization of high-level visual cortex is aligned with visual rather than abstract linguistic information | |
| ConvexGating 从单细胞流式细胞数据中的聚类推断出门控策略。 | Friedrich, V. D. | N/A | ConvexGating infers gating strategies from clusters in single cell cytometry data | |
| 单核苷酸开关赋予假单胞菌噬菌体抗性 | Vacheron, J. | N/A | Single nucleotide switches confer bacteriophage resistance to Pseudomonas protegens | |
| 疫苗诱导和混合免疫对澳大利亚昆士兰州两个队列中关注的SARS-CoV-2变种的保护作用（2021-2022年）。 | Parry, R. H. | N/A | Vaccine-induced and hybrid immunity against SARS-CoV-2 variants of concern in two cohorts in Queensland, Australia (2021-2022). | |
| 秀丽隐杆线虫（C. elegans）中的体细胞性腺形态发生需要通过HBL-1作用的异时性通路。 | Minutillo, M. | N/A | Somatic gonad morphogenesis in C. elegans requires the heterochronic pathway acting through HBL-1 | |
| 母体运动以一种与运动方式特异性的方式改变胎盘蛋白质组 | Jevtovic, F. | N/A | Maternal exercise alters placental proteome in an exercise mode-specific manner | |
| 通过BaFOMS视角解读生态流行病学系统中的记忆模式：一种贝叶斯分数阶模型选择方法 | Mestry, D. V. | N/A | Deciphering Memory Patterns in Eco-Epidemiological systems through the lens of BaFOMS: A Bayesian Fractional Order Model Selection Method | |
| 单配制果蝇会重新交配：热暴露对交配行为和繁殖力的可塑性和进化影响——以暗色果蝇为例 | Grandela, A. | N/A | Monandrous flies do remate: plastic and evolutionary consequences of heat exposure on mating behaviour and fertility in Drosophila subobscura | |
| 对在COVID-19第一波期间导致医院爆发的持久性、耐唑类药物的C. parapsilosis菌株的基因组特征分析 | Vumbaca, M. | N/A | Genomic characterization of a persistent, azole-resistant C. parapsilosis strain responsible for a hospital outbreak during the first COVID-19 wave | |
| 跨平台DNA基序发现与基准测试：探索研究不足的人类转录因子结合特异性 | Vorontsov, I. E. | N/A | Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors | |
| QT-WEAVER：尽管基因树估计存在误差，校正四重分布仍能改善系统基因组学分析 | Hasan, N. B. | N/A | QT-WEAVER: Correcting quartet distribution improves phylogenomic analyses despite gene tree estimation error | |
| GRIP：用于液相色谱梯度保留时间预测的物理信息神经网络 | George, K. | N/A | GRIP: physics-informed neural network for gradient retention time prediction in liquid chromatography | |
| 在女性中，CETP表达在冷暴露和体温中性环境下均能提高身体代谢率，从而有助于形成更为瘦削的表型。 | Castelli, J. Z. | N/A | CETP expression in females increases body metabolism under both cold exposure and thermoneutrality contributing to a leaner phenotype | |
| 使用分布式仿真在神经网络中建模神经元-星形胶质细胞相互作用 | Jiang, H.-J. | N/A | Modeling neuron-astrocyte interactions in neural networks using distributed simulation | |
| 边缘海的连通性与种群结构——综述 | Henriksson, S. | N/A | Connectivity and population structure in a marginal sea - a review | |
| 在植物协同非自体识别自交不亲和系统中协调冲突的选择压力 | Jangid, A. | N/A | Reconciling conflicting selection pressures in the plant collaborative non-self recognition self-incompatibility system | |
| 解析肺癌恶性肿瘤中复杂基因组重排的进化历程 | Hu, X. | N/A | Deconstructing evolutionary histories of complex genomic rearrangements in lung malignancies | |
| 通过上皮微生理分析平台构建的人类干细胞衍生的肾集合管模型：Epi-MAP | Hong, S. | N/A | Human Stem Cell-derived Kidney Collecting Duct Model via Epithelial Microphysiological Analysis Platform: Epi-MAP | |
| 血-肿瘤屏障类器官重现了胶质母细胞瘤微环境，并实现了治疗递送的高通量建模。 | Cho, C.-F. | N/A | Blood-tumor barrier organoids recapitulate glioblastoma microenvironment and enable high-throughput modeling of therapeutic delivery | |
| 血-肿瘤屏障类器官再现了胶质母细胞瘤微环境，并实现了治疗递送的高通量建模。 | Zhuang, P. | N/A | Blood-tumor barrier organoids recapitulate glioblastoma microenvironment and enable high-throughput modeling of therapeutic delivery | |
| 微生物群应激诱导miRNA的鉴定，与慢性鼻窦炎（CRS）的网络关系及表达 | Wei, B. | N/A | Identification of Stress-induced miRNA of Microbial flora, networking, expression with chronic rhinosinusitis (CRS) | |
| 通过基因过表达和编辑，以果实表皮特异性nsLTP启动子为目标，针对番茄果实角质层进行研究 | Alonso, M. | N/A | Targeting the tomato fruit cuticle by gene overexpression and editing with the fruit epidermis-preferential nsLTP promoter | |
| 人类单个神经元的活动受到基底外侧杏仁核内源性θ脉冲刺激的调控 | Campbell, J. M. | N/A | Human single-neuron activity is modulated by intracranial theta burst stimulation of the basolateral amygdala | |
| 通过内在运动节奏的频率失谐实现皮层手部和言语区域的功能分离。 | Anastasopoulou, I. | N/A | Functional segregation of cortical hand and speech areas by frequency detuning of an intrinsic motor rhythm. | |
| 饮食诱导的肥胖与慢性压力在小鼠更年期模型中的相互作用 | Knox, N. | N/A | The Interaction Of Diet-Induced Obesity And Chronic Stress In A Mouse Model Of Menopause | |
| 经训练的先天免疫系统减弱了巨噬细胞对癌细胞的吞噬作用 | Chatzis, A. | N/A | Trained innate immunity attenuates macrophage efferocytosis of cancer cells | |
| PGE2-cAMP和IFN-γ信号通路对TNF反应和IL-1b+巨噬细胞的调控作用 | Sokhi, U. K. | N/A | Opposing Regulation of TNF Responses and IL-1b+ Macrophages by PGE2-cAMP and IFN-g Signaling | |
| 基于质谱的抗体测序系统性基准测试揭示了方法学偏差 | Chernigovskaya, M. | N/A | Systematic benchmarking of mass spectrometry-based antibody sequencing reveals methodological biases | |
| 转录因子GABPA是原始多能性的主调控因子 | Zhou, C. | N/A | The transcription factor GABPA is a master regulator of naive pluripotency | |
| 在原代人类软骨细胞中拼接响应的QTLs，识别出潜在的骨关节炎风险基因 | Byun, S. | N/A | Response splicing QTLs in primary human chondrocytes identifies putative osteoarthritis risk genes | |
| LOL-EVE：基于进化序列预测启动子变体效应 | Shearer, C. | N/A | LOL-EVE: Predicting Promoter VariantEffects from Evolutionary Sequences | |
| 通过囊泡出口实现的非破坏性转录组学 | Armbrust, N. | N/A | Non-destructive transcriptomics via vesicular export | |
| 泛癌研究：从原发肿瘤到转移瘤的信号系统转变 | Zhou, W. | N/A | Pan-cancer study on transition of signaling systems from primary to metastatic tumors | |
| 电荷调节和离子核内环境对核小体核心颗粒的影响 | Nap, R. J. | N/A | The Impact of Charge Regulation and Ionic Intranuclear Environment on the Nucleosome Core Particle | |
| 空间转录组学揭示了急性髓系白血病在髓外和髓内组织中的炎症和转分化状态 | Dasdemir, E. | N/A | Spatial Transcriptomics Reveals Inflammation and Trans-differentiation States of Acute Myeloid Leukemia in Extramedullary and Medullary Tissues | |
| 星形胶质细胞-神经元共培养的3D肿瘤球体模型用于抗癌药物筛选 | Murugappan, S. | N/A | Astrocyte-Neuron co-cultured 3D tumor spheroid model for Anti-cancer Drug Screening | |
| 单手和双手运动学习过程中微分贝塔和伽马活动的调制 | Wu, M. | N/A | Differential beta and gamma activity modulation during unimanual and bimanual motor learning | |
| C3aR1 在 β 细胞上的作用增强了 β 细胞的功能和生存能力。 | Lima, R. | N/A | C3aR1 on β cells enhances β cell function and survival | |
| Spotiphy使得在整个切片上实现单细胞空间全转录组学成为可能 | Yang, J. | N/A | Spotiphy enables single-cell spatial whole transcriptomics across the entire section | |
| 黑素浓缩激素投射到伏隔核会增强食物消费的奖赏价值，但不会引发进食或快速眼动睡眠。 | Furman, K. L. | N/A | Melanin concentrating hormone projections to the nucleus accumbens enhance the reward value of food consumption and do not induce feeding or REM sleep | |
| 前额叶皮层编码与运动解耦的行为状态 | Rautio, I. V. | N/A | Prefrontal cortex encodes behavior states decoupled from movement | |
| 结核分枝杆菌在碳饥饿条件下的蛋白质组学特征分析 | Devlin, K. L. | N/A | Proteomic characterization of Mycobacterium tuberculosis subjected to carbon starvation | |
| 生物边界条件调控肺泡细胞对烟曲霉孢子的内化作用 | Schiefermeier-Mach, N. | N/A | Biological Boundary Conditions Regulate the Internalization of Aspergillus Fumigatus Conidia by Alveolar Cells | |
| Sigma因子作为潜在靶点以提高重组蛋白表达 | Pohlen, L. | N/A | Sigma factors as potential targets to enhance recombinant protein expression | |
| 西班牙小型陆生哺乳动物粪便样本中DNA病毒的完整基因组 | Buigues, J. | N/A | Complete genomes of DNA viruses in faecal samples from small terrestrial mammals in Spain | |
| 资源环境塑造了人类阴道微生物群的组成和稳定性。 | Kamiya, T. | N/A | Resource landscape shapes the composition and stability of the human vaginal microbiota | |
| 口服衣原体疫苗对宿主肠道微生物群和代谢物组成的影响 | Huang, Y. | N/A | Impact of oral Chlamydia Vaccination on Host Gut Microbiome and Metabolites Composition | |
| 一种用于多种致病真菌的体内烧伤伤口感染模型。 | Mercado-Soto, N. | N/A | A conserved in vivo burn wound infection model for diverse pathogenic fungi. | |
| 盐度影响了现代潮间带微生物岩的微生物碳酸盐沉淀机制 | Hsieh, Y. E. | N/A | Salinity impacted microbial carbonate precipitation mechanisms of modern microbialites in peritidal zone | |
| 鉴定出一种新的菜豆金色花叶病毒β卫星DNA，并发现与阿萨姆邦Bhut Jolokia辣椒卷叶病相关的病毒复合体 | Saikia, R. | N/A | Identification of a novel begomovirus betasatellite and occurrence of a viral complex associated with leaf curl disease in Bhut Jolokia in Assam | |
| 通过直接检测RNA氧化来定量亚细胞RNA定位 | Lo, H.-Y. G. | N/A | Quantification of subcellular RNA localization through direct detection of RNA oxidation | |
| 通过多重邻近标记技术进行染色质结构图谱绘制 | Delamarre, A. | N/A | Chromatin architecture mapping by multiplex proximity tagging | |
| 关于代码本的观点：未表征人类转录因子的序列特异性 | Jolma, A. | N/A | Perspectives on Codebook: sequence specificity of uncharacterized human transcription factors | |
| 使用meSMiLE-seq技术鉴定甲基化敏感的人类转录因子 | Gralak, A. J. | N/A | Identification of methylation-sensitive human transcription factors using meSMiLE-seq | |
| 纤维碎片化在种子种群中产生了多样性 | Pedrola, J. A. | N/A | Fibril fragmentation generates diversity in seed population | |
| 蛋白质病原性在单聚集体水平上的分子决定因素 | Urbanek, A. | N/A | Molecular determinants of protein pathogenicity at the single-aggregate level | |
| 脊椎动物R2逆转录转座子复合体在目标引导逆转录过程中的结构及第二链切割后的结构 | Thawani, A. | N/A | Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nicking | |
| 压力改变细菌生物分子凝聚物材料状态，并将其功能从mRNA降解转变为储存 | Ortiz-Rodrlguez, L. A. | N/A | Stress Changes the Bacterial Biomolecular Condensate Material State and Shifts Function from mRNA Decay to Storage | |
| 使用光学光热红外光谱技术检测未染色组织中的未标记微塑料和纳米塑料 | Duswald, K. | N/A | Detection of Unlabeled Micro- and Nanoplastics in Unstained Tissue with Optical Photothermal Infrared Spectroscopy | |
| 针对非同源末端连接与辐射在极高风险SHH型髓母细胞瘤中的合成致死性 | DeCarlo, A. | N/A | Targeting synthetic lethality between non-homologous end joining and radiation in very high-risk SHH medulloblastoma | |
| 开发评估YAP-TEAD抑制剂潜力的流程 - 直接抑制TEAD可抑制NF2突变型间皮瘤模型中的癌细胞生长 | Cunningham, R. | N/A | Development of a pipeline to evaluate YAP-TEAD inhibitor potential - direct TEAD inhibition represses cancerous growth in a NF2-mutant model of mesothelioma | |
| 突变型RIT1与YAP合作，推动类似上皮间质转化的肺癌状态 | Rominger, M. C. | N/A | Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state | |
| TLL1敲低通过增强抗肿瘤免疫抑制前列腺癌进展 | hao, j. | N/A | TLL1 knockdown attenuates prostate cancer progression by enhancing antitumor immunity | |
| TCR-TRANSLATE：生成真实抗原特异性T细胞受体序列的条件生成 | Karthikeyan, D. | N/A | TCR-TRANSLATE: Conditional Generation of Real Antigen Specific T-cell Receptor Sequences | |
| 甲型流感病毒转录生成加帽的cRNA，这些cRNA能够激活RIG-I。 | Elshina, E. | N/A | Influenza A virus transcription generates capped cRNAs that activate RIG-I | |
| 代谢见解：芽孢杆菌科微生物诱导方解石形成的机制及其在生物基建筑材料中的应用 | Michael, S. | N/A | Metabolic insights into microbially induced calcite formation by Bacillaceae for application in bio-based construction materials | |
| 使用新开发的微卫星分型检测方法研究阿萨希毛孢子菌分离株的遗传关系 | Francisco, E. C. | N/A | Investigating the genetic relationship of Trichosporon asahii isolates using a newly developed microsatellite typing assay | |
| 解析糖尿病足溃疡的分子足迹：计算机辅助发现关键蛋白质和微RNA特征 | Chudasama, J. M. | N/A | Unravelling the Molecular Footprints of Diabetic Foot Ulcers: In Silico Discovery of Key Protein and MicroRNA Signatures | |
| 用于植物基因组大小估计的流式细胞术标准的重新校准 | Soni, A. | N/A | Re-calibration of flow cytometry standards for plant genome size estimation | |
| 通过针对与冠状动脉疾病相关的基因，绘制平滑肌细胞中的动脉粥样硬化机制图谱 | Albarran-Juarez, J. | N/A | Mapping atherogenesis mechanisms in smooth muscle cells by targeting genes linked to coronary artery disease | |
| 表面重塑和细胞-基质相互作用的反转是霍乱弧菌生物膜中社群识别和分散的基础 | Moreau, A. P. | N/A | Surface remodeling and inversion of cell-matrix interactions underlies community recognition and dispersal in Vibrio cholerae biofilms | |
| 通过招募特异性泛素连接酶研究蛋白质降解性 | Shade, O. | N/A | Investigating Protein Degradability through Site-Specific Ubiquitin Ligase Recruitment | |
| 脂质驱动的SRC自缔合作用调节其转化能力 | Mohammad Jabeen, I.-L. | N/A | Lipid-driven SRC self-association modulates its transformation capacity | |
| 具有变异活性位点的古菌核糖体结构 | Nissley, A. J. | N/A | Structure of an Archaeal Ribosome with a Divergent Active Site | |
| # BioRxiv 2024-11-11 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| DAF-16/Foxo通过系统性小RNA途径抑制prg-1 piRNA突变体的跨代不育 | Simon, M. | N/A | DAF-16/Foxo suppresses the transgenerational sterility of prg-1 piRNA mutants via a systemic small RNA pathway | |
| 当没有答案比错误的答案更好时：关于批次效应的因果视角 | Bridgeford, E. W. | N/A | When no answer is better than a wrong answer: a causal perspective on batch effects | |
| 为什么棕色的幽灵在夜晚鸣叫 | Oboti, L. | N/A | Why the brown ghost chirps at night | |
| 黄素二铁蛋白通过依赖pH值的方式与类囊体膜结合，以进行由铁氧还蛋白-1驱动的O2光还原反应。 | Nikkanen, L. | N/A | Flavodiiron proteins associate pH-dependently with the thylakoid membrane for ferrdoxin-1 powered O2 photoreduction | |
| 由于不适当继承的组蛋白甲基化导致的异位转录可能会干扰终末分化细胞的正在进行的功能。 | Rodriguez, J. D. | N/A | Ectopic transcription due to inappropriately inherited histone methylation may interfere with the ongoing function of terminally differentiated cells | |
| 在不同啮齿动物杂交中，不同的复杂调控表型是导致杂交雄性不育的潜在原因。 | Hunnicutt, K. E. | N/A | Different complex regulatory phenotypes underlie hybrid male sterility in divergent rodent crosses | |
| 重新发现卵巢网：卵巢的分泌辅助结构 | Anbarci, D. N. | N/A | Rediscovering the Rete Ovarii: a secreting auxiliary structure to the ovary | |
| 使用基于聚类的排列检验来估计MEG/EEG起始时间：有多糟糕？ | Rousselet, G. A. | N/A | Using cluster-based permutation tests to estimate MEG/EEG onsets: how bad is it? | |
| Celsr3突变小鼠中的刻板行为与纹状体D3多巴胺受体的改变有关。 | Cadeddu, R. | N/A | Tic-related behaviors in Celsr3 mutant mice are contributed by alterations of striatal D3 dopamine receptors | |
| 低盐度会破坏糖海带（Saccharina latissima，褐藻门）的细菌群落。 | Schenk, S. | N/A | Low salinity destabilizes the bacterial community of sugar kelp, Saccharina latissima (Phaeophyceae) | |
| 在感知决策过程中，猕猴大脑的大规模新皮层网络中分布式证据积累 | Zou, L. | N/A | Distributed evidence accumulation across macaque large-scale neocortical networks during perceptual decision making | |
| Id 位点的共同祖先：染色体重排与多基因可能性 | Sharma, A. | N/A | Common Ancestry of the Id Locus: Chromosomal Rearrangement and Polygenic Possibilities | |
| 控制斑马鱼内胚层形成和左右模式形成的重复SOX因子的功能分化分子基础 | Johal, S. | N/A | The molecular basis for functional divergence of duplicated SOX factors controlling endoderm formation and left-right patterning in zebrafish | |
| 担子菌类真菌菌丝直径的瞬时变化 | Mazheika, I. S. | N/A | Instantaneous change in hyphal diameter in basidiomycete fungi | |
| 探索基于OPM-MEG的多变量传递熵的有向连接模式 | Pedersen, M. | N/A | Exploring Directed Connectivity Patterns of OPM-MEG with Multivariate Transfer Entropy | |
| 全基因组关联研究揭示了与杂交大鼠海洛因易感性相关的痛觉和阿片类药物消耗行为的多个基因位点 | Kuhn, B. N. | N/A | Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats | |
| GDFold2：一个快速且可并行化的蛋白质折叠环境，具有自由定义的目标函数 | Mi, T. | N/A | GDFold2: a fast and parallelizable protein folding environment with freely defined objective functions | |
| 轴突细胞器因AP-4复合体功能丧失而积聚，导致阿尔茨海默病小鼠模型中淀粉样斑块病理和胶质增生的加剧。 | Orlowski, A. | N/A | Axonal organelle buildup from loss of AP-4 complex function causes exacerbation of amyloid plaque pathology and gliosis in Alzheimers disease mouse model | |
| 使用MIDAS v3和StrainPGC准确估计宏基因组数据中的种内微生物基因含量变异 | Smith, B. J. | N/A | Accurate estimation of intraspecific microbial gene content variation in metagenomic data with MIDAS v3 and StrainPGC | |
| 急性髓系白血病线粒体通过水解ATP来抵抗化疗 | Hagen, J. T. | N/A | Acute myeloid leukemia mitochondria hydrolyze ATP to resist chemotherapy | |
| 星形胶质细胞转谷氨酰胺酶2的药理学抑制作用有助于促进神经支持性星形胶质细胞反应表型的表达，这与组蛋白乙酰化水平升高有关。 | Delgado, T. | N/A | Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation | |
| parafac4microbiome：使用平行因子分析对纵向微生物组数据进行探索性分析 | van der Ploeg, G. R. | N/A | parafac4microbiome: Exploratory analysis of longitudinal microbiome data using Parallel Factor Analysis | |
| 利用铁羟基氧化铁增强的分层磁共振成像技术绘制灵长类大脑中的血管网络结构 | Autio, J. A. | N/A | Mapping vascular network architecture in primate brain using ferumoxytol-weighted laminar MRI | |
| 解析急性运动缺陷和由小脑输出丧失引起的适应性反应 | Sinha, N. | N/A | Disentangling acute motor deficits and adaptive responses evoked by the loss of cerebellar output | |
| 一个用于系统性和可重复性研究结构-功能关系的连接组操作框架，通过模拟实现。 | Pokorny, C. | N/A | A connectome manipulation framework for the systematic and reproducible study of structure-function relationships through simulations | |
| 从鼠标视觉皮层活动重建电影 | Bauer, J. | N/A | Movie reconstruction from mouse visual cortex activity | |
| 海洋环节动物多室草苔虫的基因组资源 | Mutemi, K. N. | N/A | A genome resource for the marine annelid Platynereis dumerilii | |
| 非自主性胰岛素信号传导可延缓秀丽隐杆线虫生殖系干细胞和祖细胞的有丝分裂进程。 | Cheng, E. | N/A | Non-autonomous insulin signaling delays mitotic progression in C. elegans germline stem and progenitor cells | |
| 计算建模揭示了纹状体亚区域特异性多巴胺动态的关键决定因素 | Ejdrup, A. L. | N/A | Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum | |
| 在人类和恒河猴中，HIV-1的进化动力学与广泛中和抗体的产生 | Shimagaki, K. S. | N/A | Parallel HIV-1 evolutionary dynamics in humans and rhesus macaques who develop broadly neutralizing antibodies | |
| 蛋白质-蛋白质相互作用对酪氨酸磷酸酶PTP1B的别构调控 | Chartier, C. A. | N/A | Allosteric regulation of the tyrosine phosphatase PTP1B by a protein-protein interaction | |
| 韩国都湖组（中新世）中新发现的金枪鱼标本（属Auxis） | Suh, D. | N/A | A new tuna specimen (Genus Auxis) from the Duho Formation (Miocene) of South Korea | |
| 在微流控芯片上利用人胚胎干细胞衍生的类器官模拟软骨内骨化初期的血管动力学 | Kesharwani, A. | N/A | Modeling vascular dynamics at the initial stage of endochondral ossification on a microfluidic chip using a human embryonic-stem-cell-derived organoid | |
| 横断面的脑龄评估在预测未来脑部变化方面存在局限性。 | Korbmacher, M. | N/A | Cross-sectional brain age assessments are limited in predicting future brain change | |
| 细胞衍生基质的纳米力学作为胶原蛋白VI相关先天性肌营养不良症的功能读数 | White, T. | N/A | Nanomechanics of cell-derived matrices as a functional read-out in Collagen VI-related Congenital Muscular Dystrophies | |
| Evolvoid：一种用于塑造最佳细胞结构的遗传算法 | Mancini, P. | N/A | Evolvoid: A genetic algorithm for shaping optimal cellular constructs | |
| 成年大鼠的多重情境辨别：性别差异及厌恶记忆的时间依赖性泛化动态 | Alves, F. N. L. | N/A | Multiple context discrimination in adult rats: sex variability and dynamics of time-dependent generalization of an aversive memory | |
| LipiDetective - 一种用于识别串联质谱中分子脂质种类的深度学习模型 | Wuerf, V. | N/A | LipiDetective - a deep learning model for the identification of molecular lipid species in tandem mass spectra | |
| 多巴胺和皮质iPSC衍生的神经元在不同的帕金森病突变中显示出溶酶体和线粒体功能障碍的差异：这对蛋白质沉积与选择性细胞丢失的影响 | Chedid, J. | N/A | Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss | |
| 在刚地弓形虫入侵过程中，宿主细胞质膜的穿孔需要棒状体胞吐作用。 | Male, F. | N/A | Perforation of the host cell plasma membrane during Toxoplasma gondii invasion requires rhoptry exocytosis | |
| 代谢物营养图谱指南 - 揭示与疾病病因相互作用的代谢物营养图谱 | Wuerf, V. | N/A | MeNu GUIDE - a metabolite nutrition graph to uncover interactions with disease etiology | |
| 一种跨动物和环境的普遍海马记忆编码 | Wirtshafter, H. S. | N/A | A universal hippocampal memory code across animals and environments | |
| 智能分布式数据工厂：面向主动学习驱动分子数据采集的志愿者计算平台 | Ghukasyan, T. | N/A | Smart Distributed Data Factory: Volunteer Computing Platform for Active Learning-Driven Molecular Data Acquisition | |
| 洗牌：扩展合成生物学工具箱以适应类似洗牌重组系统 | Katalinic, J. | N/A | Do the shuffle: Expanding the synthetic biology toolkit for shufflon-like recombination systems | |
| 使用多重竞争性等位基因特异性PCR（mxKASP）基因分型确定合子性 | de Visser, M. C. | N/A | Determining zygosity with multiplex Kompetitive Allele-Specific PCR (mxKASP) genotyping | |
| 保守的基因内容和独特的系统发育历史特征了Triturus平衡致死系统背后的“bloopergene” | de Visser, M. C. | N/A | Conserved gene content and unique phylogenetic history characterize the 'bloopergene' underlying Triturus' balanced lethal system | |
| NewtCap：一种高效的目标捕获方法，用于提升蝾螈科（真蝾螈和新蝾螈）基因组研究 | de Visser, M. C. | N/A | NewtCap: an efficient target capture approach to boost genomic studies in Salamandridae (True Salamanders and Newts) | |
| PAV-spotter：利用信号互相关识别目标捕获数据中的存在/缺失变异 | de Visser, M. C. | N/A | PAV-spotter: using signal cross-correlations to identify Presence/Absence Variation in target capture data | |
| 鲸鱼语言模型（WhaleLM）：利用机器学习在抹香鲸的声音和行为中寻找结构与信息 | Sharma, P. | N/A | WhaleLM: Finding Structure and Information in Sperm Whale Vocalizations and Behavior with Machine Learning | |
| 基因组证据表明，Triturus蝾螈中的平衡致死系统起源于一次瞬间的物种形成事件。 | France, J. M. | N/A | Genomic evidence suggests the balanced lethal system in Triturus newts originated in an instantaneous speciation event. | |
| 使用CSI-TME识别IDH突变型胶质瘤肿瘤微环境中预后细胞状态相互作用 | Singh, A. | N/A | Identifying Prognostic Cell State Interactions in the Tumor Microenvironment of IDH-Mutant Gliomas Using CSI-TME | |
| 底物利用和交叉喂养协同作用决定微生物群对病原体入侵的抵抗力 | Yang, X. | N/A | Substrate utilization and cross-feeding synergistically determine microbiome resistance to pathogen invasion | |
| BNT162b2 JN.1-和KP.2-适应型COVID-19疫苗的免疫学和生物物理特性 | Chen, W. | N/A | Immunologic and Biophysical Features of the BNT162b2 JN.1- and KP.2-Adapted COVID-19 Vaccines | |
| 对两种稀有鲸类物种解剖学的贡献：沙漏海豚（Lagenorhynchus cruciger）与眼镜海豚（Phocoena dioptrica） | Graic, J.-M. | N/A | A Contribution To The Anatomy Of Two Rare Cetacean Species: The Hourglass Dolphin (Lagenorhynchus cruciger) And The Spectacled Porpoise (Phocoena dioptrica) | |
| 通过泛基因组学鉴定和表征古菌假肽聚糖生物合成基因 | Lupo, V. | N/A | Identification and Characterization of Archaeal Pseudomurein Biosynthesis Genes through Pangenomics | |
| 基于图像的低嵌合体体细胞移动元件插入检测的DNA测序编码 | Tan, M. | N/A | Image-based DNA Sequencing Encoding for Detecting Low-Mosaicism Somatic Mobile Element Insertions | |
| 子宫内膜蜕膜化反应的停滞决定了流产的复发风险 | Muter, J. | N/A | Stalling of the endometrial decidual reaction determines the recurrence risk of miscarriage | |
| ERP和神经振荡能否用于区分在生态学上有效的运动模型中熟练和不熟练玩家的表现？ | Winstanley, M. | N/A | Can ERPs and neural oscillations be used to differentiate skilled and unskilled player performance in an ecologically valid sporting model? | |
| Tidyplots 赋予生命科学家通过简单代码实现数据可视化的能力。 | Engler, J. B. | N/A | Tidyplots empowers life scientists with easy code-based data visualization | |
| 血管转录因子TMO5调控PIN1极性及器官发生：在芽分生组织中作为MONOPTEROS的下游因子 | Kareem, A. | N/A | Vascular Transcription Factor TMO5 Regulates PIN1 Polarity andOrganogenesis Downstream of MONOPTEROS in the Shoot Meristem | |
| 纠缠适应性景观通过外适应促进基因调控的进化 | Westmann, C. A. | N/A | Entangled adaptive landscapes facilitate the evolution of gene regulation by exaptation | |
| 纠缠适应性景观通过外适应促进基因调控的进化 | Westmann, C. A. | N/A | Entangled adaptive landscapes facilitate the evolution of gene regulation by exaptation | |
| 海马、纹状体和眶额皮质对时间信息的同步处理 | Shimbo, A. | N/A | Synchronous processing of temporal information across the hippocampus, striatum, and orbitofrontal cortex | |
| 依赖于颗粒细胞的处理对于运动学习至关重要，但对于许多依赖小脑的行为来说却是可有可无的。 | Lee, J.-H. | N/A | Processing reliant on granule cells is essential for motor learning but dispensable for many cerebellar-dependent behaviors | |
| 单细胞转录组学揭示埃及伊蚊中肠和脂肪体在吸血后的表达图谱 | Vial, T. | N/A | Single-cell transcriptional landscapes of Aedes aegypti midgut and fat body after a bloodmeal | |
| 对比增强微型CT成像揭示了胎儿女性盆底解剖细节 | Aaldijk, D. | N/A | Contrast-Enhanced Micro-CT Imaging of a Foetal Female Pelvic Floor Reveals Anatomical Details | |
| 长读RNA测序揭示了源自人类皮层神经元的转录本特异性调控 | Xu, J. | N/A | Long-Read RNA-sequencing reveals transcript-specific regulation in human-derived cortical neurons | |
| 不同结合模式下的跨峰交联提示SARS-CoV-2抗体中和的补充机制 | Nan, X. | N/A | Distinct Binding Modes of Inter-Spike Cross-Linking Suggest a Supplementary Mechanism for SARS-CoV-2 Antibody Neutralization | |
| ADP-MoA：一种用于筛选抗生素活性及其在铜绿假单胞菌中作用机制的平台 | Valencia Morante, E. Y. | N/A | ADP-MoA: a platform for screening antibiotic activity and their mechanism of action in Pseudomonas aeruginosa | |
| 内质网对脂质代谢的感知驱动了PRA家族依赖的COPII囊泡运输调控 | Nakazato, M. | N/A | ER sensing of lipid metabolism drives PRA family-dependent regulation of COPII vesicle transport | |
| 在秀丽隐杆线虫中进行的fat-2(wa17)抑制因子筛选揭示了适应多不饱和脂肪酸缺乏的遗传机制 | Kaper, D. | N/A | A fat-2(wa17) suppressor screen in C. elegans reveals genetic adaptations to polyunsaturated fatty acid deficiency | |
| 健康人群的综合多组学分析 | Visser, C. | N/A | Comprehensive multi-omics profiling of a healthy human cohort | |
| 极化剂AsymPolPOK在完整和裂解的哺乳动物细胞中的稳定性 | Lacasga, D. | N/A | Stability of the polarization agent AsymPolPOK in intact and lysed mammalian cells | |
| 线粒体VDAC2的构象可塑性控制其与细胞质蛋白相互作用的动态过程 | Rosencrans, W. M. | N/A | Conformational plasticity of mitochondrial VDAC2 controls the kinetics of its interaction with cytosolic proteins | |
| 五聚体尾管蛋白在SPR噬菌体中的组装结构 | Zhu, H. | N/A | Architecture of a pentameric assembly of the tail tube protein in SPR phages | |
| 用于预测蛋白质pKa值和离子化状态的KaMLs：树结构是否足够？ | Shen, M. | N/A | KaMLs for Predicting Protein pKa Values andIonization States: Are Trees All You Need? | |
| 成像活鼠、死鼠以及处于应激状态的植物的超微弱光子发射 | SALARI, V. | N/A | Imaging Ultraweak Photon Emission from Living and Dead Mice and from Plants under Stress | |
| 基于细胞位置的多细胞系统中细胞力学特征评估 | Koyama, H. | N/A | Cell position-based evaluation of mechanical features of cells in multicellular systems | |
| FRET和生物膜干涉技术揭示的NAD+核开关配体结合特性 | Conoan Nieves, N. E. | N/A | Ligand binding characteristics of an NAD+ riboswitch revealed by FRET and biolayer interferometry | |
| Notch信号通路中二价异源三聚体结合的热力学 | Cook, C. | N/A | Thermodynamics of Bivalent Heterotrimer Association in the Notch Signaling Pathway | |
| 泛紧密连接蛋白结合分子调节细胞旁屏障的生物物理基础 | Ogbu, C. P. | N/A | Biophysical Basis of Paracellular Barrier Modulation by a Pan-Claudin-Binding Molecule | |
| 通过液体振荡使转甲状腺素蛋白聚集 | Ritsch, I. | N/A | Aggregation of Transthyretin by Fluid Agitation | |
| 人类和小鼠胰岛素中的一种翻译后半胱氨酸到丝氨酸的转化，产生了一种糖尿病相关的新表位。 | Srivastava, N. | N/A | A post-translational cysteine-to-serine conversion in human and mouse insulin generates a diabetogenic neoepitope | |
| 人类活动而非环境因素是台湾地区斯克里普斯孢菌和洛门托孢菌分布的主要驱动力。 | Wu, H.-M. | N/A | Human activity, not environmental factors, drives Scedosporium and Lomentospora distribution in Taiwan | |
| MAGE：异常基因表达的蒙特卡罗方法 | Beltran, M. | N/A | MAGE: Monte Carlo method for Aberrant Gene Expression | |
| 使用少样本学习准确预测体细胞系和合子中CRISPR编辑结果 | Zheng, W. | N/A | Accurate prediction of CRISPR editing outcomes in somatic cell lines and zygote with few-shot learning | |
| MOSAIC：微生物组研究分析整合与校正的管道 | Fu, C. | N/A | MOSAIC: A Pipeline for MicrobiOme Studies Analytical Integration and Correction | |
| 人类着丝粒和近着丝粒区域中的类昆虫痘病毒长DNA序列 | Hondo, E. | N/A | Entomopoxvirus-like long DNA sequences in human centromeric and peri-centromeric regions | |
| 通过计算机模拟识别针对四种感染性不动杆菌的新型共同药物靶点 | Rahman, S. | N/A | In silico Identification of Novel Common Drug Targets Against Four Infectious Acinetobacter Species | |
| 结直肠癌III期单细胞空间图谱 | Su, A. | N/A | The single-cell spatial landscape of stage III colorectal cancers | |
| 综合蛋白质组-基因组分析揭示了HER2阳性乳腺癌中拉帕替尼耐药的关键生物标志物 | Steggall, J. | N/A | Integrative proteo-genomic profiling uncovers key biomarkers of lapatinib resistance in HER2-positive breast cancer | |
| 多巴胺D2受体激动剂可抑制神经内分泌肿瘤血管生成，从而抑制化疗耐药的小细胞肺癌进展 | Alam, S. K. | N/A | Dopamine D2 receptor agonists abrogate neuroendocrine tumour angiogenesis to inhibit chemotherapy-refractory small cell lung cancer progression | |
| 视黄醇浸渍的纳米颗粒通过在小鼠体内对软骨内骨化的位点特异性调节，实现了对骨骼生长的控制。 | Matsuoka, M. | N/A | Retinoid-impregnated nanoparticles enable control of bone growth by site-specific modulation of endochondral ossification in mice | |
| 活体木质部细胞编码大量负责维管汁液肽的保守基因家族 | Lu, M. R. | N/A | Living xylem cells encode a large number of conserved gene families responsible for vascular sap peptides | |
| 偏移质量载体蛋白质组提高多重单细胞蛋白质组学定量 | Cheung, T. | N/A | Offset mass carrier proteome improves quantification of multiplexed single cell proteomics | |
| 通过DBiTplus技术在同一组织切片上整合基于成像和基于测序的空间组学图谱 | Enninful, A. | N/A | Integration of Imaging-based and Sequencing-based Spatial Omics Mapping on the Same Tissue Section via DBiTplus | |
| iPAR：一种在风险人群未知情况下，用于建模和推断疾病传播信息的框架 | Catterall, S. | N/A | iPAR: A framework for modelling and inferring information about disease spread when the populations at risk are unknown | |
| 白芷及其根际微生物对空心莲子草处理的生态响应 | Huang, Y. | N/A | Ecological response of Angelica dahurica and its rhizosphere microorganisms to treatments of Alternanthera philoxeroides | |
| 描述指猴（Daubentonia madagascariensis）中新种系突变的速率和模式 | Versoza, C. J. | N/A | Characterizing the rates and patterns of de novo germline mutations in the aye-aye (Daubentonia madagascariensis) | |
| 指猴（Daubentonia madagascariensis）的结构变异景观 | Versoza, C. J. | N/A | The landscape of structural variation in aye-ayes (Daubentonia madagascariensis) | |
| 基于谱系的指猴（Daubentonia madagascariensis）交叉与非交叉图谱 | Versoza, C. J. | N/A | A pedigree-based map of crossovers and non-crossovers in aye-ayes (Daubentonia madagascariensis) | |
| 疾病相关调控DNA变异与表皮稳态转录因子 | Porter, D. F. | N/A | Disease-Linked Regulatory DNA Variants and Homeostatic Transcription Factors in Epidermis | |
| 研究管理决策在野生火鸡分布范围内亚种杂交中的作用 | Beckman, A. K. | N/A | Investigating the Role of Management Decisions in Subspecies Hybridization Across the Wild Turkey's Range | |
| 烟酰胺腺嘌呤二核苷酸、三磷酸腺苷及氧化剂诱导的甘油醛-3-磷酸脱氢酶高阶构象变化的分析 | Suzuki, H. | N/A | Analysis of the high-order conformational changes in glyceraldehyde-3-phosphate dehydrogenase induced by nicotinamide adenine dinucleotide, adenosine triphosphate, and oxidants | |
| 多样化的膜结合酰基转移酶的结构统一揭示了一种保守的折叠结构，这种结构定义了跨膜酰基转移酶（Transmembrane Acyl Transferase, TmAT）超家族。 | Kinniment-Williams, B. E. | N/A | Structural unification of diverse membrane-boundacyltransferases reveals a conserved fold that defines the Transmembrane Acyl Transferase (TmAT) superfamily | |
| 超声组织消融术和人类多能干细胞衍生的肝球植入术作为先天性代谢性肝病潜在治疗手段的安全性和有效性：在免疫健全的啮齿动物模型中的评估。 | Rashidi, H. | N/A | The safety and efficacy of Ultrasound Histotripsy and human pluripotent stem cell-derived hepatic spheroid implantation as a potential therapy for treatment of congenital metabolic liver disease: assessment in an immunocompetent rodent model. | |
| 人体器官尺度上的物理玻璃化和纳米升温技术，以实现冷冻保存 | Gangwar, L. | N/A | Physical vitrification and nanowarming at human organ scale to enable cryopreservation | |
| 从人类肠道类器官实时测量血清素动态 | Bohl, B. | N/A | Measurement of Real Time Serotonin Dynamics from Human Derived Gut Organoids | |
| 儿童唾液DNA甲基化分析中细胞类型异质性的考量：参考面板比较与按估算细胞类型比例的分层 | Chan, M. H.-M. | N/A | Considerations for Cell Type Heterogeneity in Pediatric Salivary DNA Methylation Analyses: Comparison of Reference Panels & Stratification by Estimated Cell TypeProportion | |
| 通过序列嵌入进行RNA-蛋白质相互作用分类 | Matus, D. | N/A | RNA-Protein Interaction Classification via Sequence Embeddings | |
| 基于类固醇代谢途径的新型深度神经网络模型的生物年龄预测 | Wang, Q. | N/A | Biological age prediction using a novel DNN model based on steroid metabolic pathways | |
| NOODAI：面向网络的多组学数据分析与整合管道的网络服务器 | Totu, T. | N/A | NOODAI: A webserver for network-oriented multi-omics data analysis and integration pipeline | |
| 苯并尼达唑抗性克氏锥虫克隆的转录组分析揭示了硝基还原酶I非依赖性抗性机制 | Mejia-Jaramillo, A. M. | N/A | Transcriptomic analysis of benznidazole-resistant Trypanosoma cruzi clone reveals nitroreductase I-independent resistance mechanisms | |
| 迁移学习和DNA语言模型提升转录因子结合预测 | Aksu, E. D. | N/A | Transfer learning and DNA language models enhance transcription factor binding predictions | |
| 系统识别和表征病毒长链非编码RNA（lncRNA）表明，病毒lncRNA广泛模拟宿主lncRNA的结构。 | Fu, P. | N/A | Systematic identification and characterization of virus lncRNAs suggests extensive structural mimicry of host lncRNAs | |
| 一个稳健的工作流程用于基准测试多组学数据的反卷积 | Amblard, E. | N/A | A robust workflow to benchmark deconvolution of multi-omic data | |
| 通过双聚类分析揭示英国生物银行中的隐性基因-性状模式 | Pividori, M. | N/A | Uncovering hidden gene-trait patterns through biclustering analysis of the UK Biobank | |
| 将结构表示提取到蛋白质序列模型中 | Ouyang-Zhang, J. | N/A | Distilling structural representations into protein sequence models | |
| 针对急性髓系白血病干细胞治疗后复发中的IL-1/IRAK1/4信号传导 | Ho, T.-C. | N/A | Targeting IL-1/IRAK1/4 signaling in Acute Myeloid Leukemia Stem Cells Following Treatment and Relapse | |
| 健康B细胞：CAR-T细胞免疫疗法的盟友还是对手？ | Paixao, E. A. | N/A | Healthy B cells: allies or adversaries of CAR-T cell immunotherapy? | |
| 骨髓微环境特征与HMA耐药MDS患者接受吉达西他滨和阿替利珠单抗治疗后的患者生存相关 | Jang, H. J. | N/A | Bone marrow microenvironment signatures associate with patient survival after guadecitabine and atezolizumab therapy in HMA-resistant MDS | |
| HHLA2介导的配体非依赖性c-Met激活驱动肝细胞癌并预测c-MET抑制剂疗效 | huang, x. | N/A | Ligand-independent c-Met activation by HHLA2 drives hepatocellular carcinoma and predicts c-MET inhibitor efficacy | |
| 单细胞视频追踪以识别聚集行为 | Korsnes, M. S. | N/A | Video tracking of single cells to identify clustering behaviour | |
| 晚更新世巴西东南部灰侏儒鹿摄食策略的千年尺度稳定性。 | Hubbe, A. | N/A | Late Quaternary millennial-scale stability of the feeding strategy of the gray brocket deer in Southeastern Brazil. | |
| 绿合成、表征及以Talinum triangulare叶提取物为媒介的Ag-MgO纳米复合材料的潜在抗菌研究 | Fonye Nyuyfoni, G. | N/A | Green synthesis, characterization, and potential antimicrobial studies of Ag-MgO nanocomposites mediated from Talinum triangulare leaf extract | |
| 高强度间歇运动对心肺和神经肌肉反应的性别差异 | Wilson, H. | N/A | Sex differences in the cardiopulmonary and neuromuscular response to high-intensity interval exercise | |
| 质外体代谢组学揭示了植物-病原体相互作用受氮素供应的调控 | Jeridi, R. | N/A | Apoplast metabolomics reveals that plant-pathogen crosstalk is modulated by nitrogen supply | |
| 海生被子植物大叶藻（Zostera marina）中，成花素和抗成花素基因的表达与生殖状态相关。 | Nolan, C. T. | N/A | Florigen and antiflorigen gene expression correlates with reproductive state in a marine angiosperm, Zostera marina | |
| 预测化合物在Reactome知识库中的路径参与情况 | Huckvale, E. D. | N/A | Predicting the Pathway Involvement of Compounds Annotated in the Reactome Knowledgebase | |
| 密度依赖性如何调节害虫的种群控制：遗传生物防治的视角 | Butler, C. D. | N/A | How population control of pests is modulated by density dependence: The perspective of genetic biocontrol | |
| 里海海平面快速下降需要动态时空保护规划，以保持生物多样性保护措施的相关性。 | Court, R. | N/A | Rapid Caspian sea level decline requires dynamic spatio-temporal conservation planning to keep biodiversity protection measures relevant | |
| 从高质量的全基因组群体水平数据推断指猴（Daubentonia madagascariensis）的种群历史 | Terbot, J. W. | N/A | Inferring the demographic history of aye-ayes (Daubentonia madagascariensis) from high-quality, whole-genome, population-level data | |
| 暗翅蕈蚊Lycoriella ingenua的初级性别比例的母系遗传 | Shlyakonova, M. | N/A | Maternal inheritance of primary sex ratios in the dark-winged fungus gnat Lycoriella ingenua | |
| 利用一个拟合良好的进化基准模型，对指猴（Daubentonia madagascariensis）进行全基因组扫描，以寻找近期正选择和平衡选择的证据。 | Soni, V. | N/A | A whole-genome scan for evidence of recent positive and balancing selection in aye-ayes (Daubentonia madagascariensis) utilizing a well-fit evolutionary baseline model | |
| 冬小麦产量及产量表型可塑性的遗传调控 | Giordano, N. | N/A | Genetic modulation of yield and phenotypic plasticity of yield in winter wheat | |
| 秀丽隐杆线虫中RNA结合与调控蛋白的全景图 | Laver, J. D. | N/A | A global view of the RNA-binding and regulatory protein landscape in Caenorhabditis elegans | |
| 基于无细胞RNA中可转座元件特征的子痫前期早期预测 | Patel, M. | N/A | Early Prediction of Preeclampsia Based on Transposable Elements signature in cell-free RNA | |
| 巨型鞭蠹（Mastigoproctus giganteus）染色体水平基因组显示出前志留纪全基因组复制的特征。 | Kulkarni, S. | N/A | A chromosome-level genome of the giant vinegaroon Mastigoproctus giganteus exhibits the signature of pre-Silurian whole genome duplication | |
| 通过细胞表面和病毒包膜工程的配对增强了对哺乳动物细胞的慢病毒基因递送 | Tannir, R. | N/A | Enhanced lentiviral gene delivery to mammalian cells via paired cell surface and viral envelope engineering | |
| 胶质母细胞瘤驱动蛋白酶非依赖性的微胶质细胞外基质侵袭 | Chang, C.-W. | N/A | Glioblastoma Drives Protease-Independent Extracellular Matrix Invasion of Microglia | |
| 从单细胞数据推断细胞类型特异性共表达基因 | Shan, X. | N/A | Inferring Cell-Type-Specific Co-Expressed Genes from Single Cell Data | |
| 一种适用于深度自上而下蛋白质组学的全窗口数据独立采集方法 | Sun, C. | N/A | A Full Window Data Independent Acquisition Method for DeeperTop-down Proteomics | |
| CelLink：整合具有少量关联特征和不平衡细胞群体的单细胞多组学数据 | Luo, X. | N/A | CelLink: Integrate single-cell multi-omics data with few linked features and imbalanced cell populations | |
| ScisTree2：一种改进的大规模推断细胞谱系树和从噪声单细胞数据进行基因型调用的方法 | Zhang, H. | N/A | ScisTree2: An Improved Method for Large-scale Inference of Cell Lineage Trees and Genotype Calling from Noisy Single Cell Data | |
| 来自海洋水柱中全海洋深度原核生物的小蛋白 | Wang, Y. | N/A | Small proteins from prokaryotes in marine water column at full ocean depth | |
| 慢性间歇性乙醇通过内源性大麻素非依赖性机制在小鼠中产生痛觉 | Miliano, C. | N/A | Chronic intermittent ethanol produces nociception through endocannabinoid-independent mechanisms in mice | |
| 使用氯胺酮作为潜在抗抑郁剂后对两性青春期大鼠的安全性担忧 | Jornet-Plaza, J. | N/A | Safety concerns following the use of ketamine as a potential antidepressant for adolescent rats of both sexes | |
| 铜绿假单胞菌吡咯喹啉醌和1-羟基吩嗪对人类鼻上皮细胞内钙离子、线粒体功能及存活率的影响 | Thompson, J. C. | N/A | Effects of Pseudomonas aeruginosa pyocyanin and 1-hydroxyphenazine on intracellular calcium, mitochondrial function, and viability in human nasal epithelial cells | |
| 长期存在于肝脏中的记忆T细胞，其特异性偏向于丰富的子孢子抗原，通过辐射减毒子孢子疫苗驱动疟疾保护作用。 | de Menezes, M. N. | N/A | Long lived liver-resident memory T cells of biased specificities for abundant sporozoite antigens drive malaria protection by radiation-attenuated sporozoite vaccination | |
| 长期存活的肝驻留记忆T细胞，其特异性偏向于丰富的子孢子抗原，通过辐射减毒子孢子疫苗驱动疟疾保护作用。 | de Menezes, M. N. | N/A | Long lived liver-resident memory T cells of biased specificities for abundant sporozoite antigens drive malaria protection by radiation-attenuated sporozoite vaccination | |
| 鉴定和表征具有高亲和力和强效抗白血病活性的血管活性肠肽受体拮抗剂 | Wang, Y. | N/A | Identification and characterization of vasoactive intestinal peptide receptor antagonists with high-affinity and potent anti-leukemia activity | |
| 理解城市食品生产中的授粉：公民科学项目设计中数据验证和参与者反馈的重要性 | Nicholls, E. | N/A | Understanding pollination in urban food production: the importance of data validation and participant feedback for citizen science project design | |
| 在气候变化背景下人类改造景观中的生态同步性 | Song, Y. | N/A | Ecological synchrony in human-modified landscapes under a changing climate | |
| 环境与个体变异对小型实验种群灭绝时间模式的影响。 | Bakker, S. | N/A | Effects of environmental and individual variation on time patterns of extinction in small experimental populations. | |
| 评估密西西比湾（美国）搁浅的大西洋宽吻海豚（Tursiops truncatus）的遗传多样性 | Arick, M. | N/A | Assessment of the Genetic Diversity of Atlantic Bottlenose Dolphin (Tursiops truncatus) Strandings in the Mississippi Sound (USA) | |
| 结合便携式样品制备和逆转录环介导等温扩增的柑橘衰退病毒快速比色检测 | Liu, C.-W. | N/A | Rapid colorimetric detection of citrus tristeza virus combining portable sample preparation and reverse transcription-loop mediated isothermal amplification | |
| 扩张型心肌病中TITIN变异的含义：整合全外显子测序与分子动力学模拟研究 | Mukhopadhyay, A. | N/A | Implication of TITIN Variations in Dilated Cardiomyopathy: Integrating Whole Exome Sequencing With Molecular Dynamics Simulation Study | |
| 综合多组学分析揭示巨噬细胞如何驱动乳腺癌中的免疫抑制并影响临床结果 | Azimzade, Y. | N/A | Integrated multiomics analysis unveils how macrophages drive immune suppression in breast tumors and affect clinical outcomes | |
| scLong：用于捕捉单细胞转录组学中长程基因背景的十亿参数基础模型 | Bai, D. | N/A | scLong: A Billion-Parameter Foundation Model for Capturing Long-Range Gene Context in Single-Cell Transcriptomics | |
| 产前砷暴露与胎儿肝脏、心脏、肺和胎盘中基因表达的关系 | Rychlik, K. A. | N/A | Prenatal Arsenic Exposure and Gene Expression in Fetal Liver, Heart, Lung, and Placenta | |
| 芹菜油（Apium graveolens）-肉豆蔻酸基微乳体系的体外抗癌、抗炎和抗氧化活性：表征与生物医学应用 | Govindaswamy, B. | N/A | In vitro anti cancer, anti inflammatory and anti oxidant activity of Celery oil (Apium graveolens)-Myristic acid based microemulsion system: Characterization and Biomedical application | |
| 多扎格列汀和肠促胰岛素在胰岛素分泌中的性别依赖性加性效应：一种新型GCK-MODY小鼠模型的研究 | Salazar, S. | N/A | Sex-dependent additive effects of dorzagliatin and incretin on insulin secretion in a novel mouse model of GCK-MODY | |
| 预印本与期刊文章：COVID-19研究中的引用影响 | Tsunoda, H. | N/A | Preprints vs. Journal Articles: Citation Impact in COVID-19 Research | |
| 能够选择性靶向RAS驱动型癌症的合成基因电路 | Senn, G. V. | N/A | Synthetic gene circuits that selectively target RAS-driven cancers | |
| 多组学分析揭示了来自海鞘Botryllus schlosseri的微生物衍生代谢物在金属相互作用中的重要作用 | Matus, D. G. G. | N/A | Multi-omics Analysis Reveals Important Role for Microbial-derived Metabolites from Botryllus schlosseri in Metal Interactions | |
| 植物高度动态杂种优势的代谢途径在水稻中是稳健的生物标志物。 | Dan, Z. | N/A | The metabolic pathways underlying dynamic heterosis for plant height are robust biomarkers in rice | |
| 夜行性土豚（Orycteropus afer，管齿目）的眼部特征与视网膜感光细胞 | Peichl, L. | N/A | Eye features and retinal photoreceptors of the nocturnal aardvark (Orycteropus afer, Tubulidentata) | |
| 老化大脑的自由水消除径向测量法 | Chang, K. H. | N/A | Free water elimination tractometry for aging brains | |
| 超越字母：最优传输作为亚字母正字法处理的模型 | Taylor, J. E. | N/A | Beyond Letters: Optimal Transport as a Model for Sub-Letter Orthographic Processing | |
| 皮层内微刺激导致脑血流与神经活动空间错配 | Yonza, A. K. I. | N/A | Spatially mismatched cerebral blood flow and neuronal activity by intracortical microstimulation | |
| 个性化fMRI引导rTMS目标的分水岭算法图形用户界面 | Feng, Z.-j. | N/A | A Watershed Algorithm GUI for Personalized fMRI-guided rTMS Target | |
| 系统性自身免疫病中常见罕见和新奇的RELA变异 | Downes, M. B. | N/A | Rare and novel RELA variants are common in systemic autoimmunity | |
| 在两匹患有急性呼吸综合征的马的淋巴结和肺组织中发现的昆虫特异性阿尔法介体病毒1（Mesoniviridae科） | Jurisic, L. | N/A | Insect-specific Alphamesonivirus-1 (Mesoniviridae) in lymph node and lung tissues from two horses with acute respiratory syndrome | |
| 蛇纹岩的微生物生态学 | Colman, D. R. | N/A | The Microbial Ecology of Serpentinites | |
| 圈养繁殖的墨西哥钝口螈在恢复和人工湿地中的运动生态学：两栖动物再引入和迁徙的保育启示 | Ramos, A. G. | N/A | Movement ecology of captive-bred axolotls in restored and artificial wetlands: conservation insights for amphibian reintroductions and translocations | |
| 野生动物贸易的过度监管 | Challender, D. | N/A | Disproportionate regulation of wildlife trade | |
| 大规模遥感数据显示，德国的树木死亡率似乎高于之前的预期。 | Schiefer, F. | N/A | Large-scale remote sensing reveals that tree mortality in Germany appears to be greater than previously expected | |
| 与火灾后的模式相比，在皆伐和抢救性采伐后的土壤群落具有不同的早期演替动态。 | Porter, T. M. | N/A | Soil communities following clearcut and salvage harvest have different early successional dynamics compared with post-wildfire patterns | |
| 多源摄影证据评估亚洲象的走廊使用情况、作物侵袭行为及身体伤害 | NR, A. | N/A | Multi-source photographic evidence to assess corridor use, crop-raiding behaviour, and body injuries in Asian elephants | |
| 大量开花和花期不同步是西高止山脉一个季节性草本植物群落的特征。 | Shrotri, S. | N/A | Mass flowering and flowering asynchrony characterise a seasonal herbaceous community in the Western Ghats | |
| 通过扩展的DEST 2.0基因组资源，在结构化种群的D. melanogaster中全球适应的足迹 | Nunez, J. C. B. | N/A | Footprints of worldwide adaptation in structured populations of D. melanogaster through the expanded DEST 2.0 genomic resource | |
| 被子植物中葡萄性别决定区域的演化历史及葡萄科中雌雄异株的出现 | Massonnet, M. | N/A | Evolutionary history of the grape sex-determining region in angiosperms and emergence of dioecy in Vitaceae | |
| mRNP组成的各种改变会引发有害R-loop的增加 | Merida-Cerro, J. A. | N/A | Different alterations in mRNP composition trigger an increase in harmful R-loops | |
| 大鼠单核多器官染色质可及性图谱 | Li, R. | N/A | Single-nucleus multiple-organ chromatin accessibility mapping in the rat | |
| 蜜蜂嗅觉行为的机器学习在野外自由飞行的蜜蜂中识别出排斥性气味物质 | Kowalewski, J. | N/A | Machine learning of honey bee olfactory behavior identifies repellent odorants in free flying bees in the field | |
| 人类行走的能量消耗作为不平坦地形幅度的函数 | Hosseini-Yazdi, S.-S. | N/A | The energetic cost of human walking as a function of uneven terrain amplitude | |
| 可编程蛋白质降解剂能够在体外和体内选择性敲低致病性β-连环蛋白亚群 | Ye, T. | N/A | Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo | |
| 评估深度学习生成的三维分子的构象有效性和合理性 | Fan, F. | N/A | Assessing Conformation Validity and Rationality of Deep Learning-Generated 3D Molecules | |
| 利用进化尺度建模的深度学习方法发现针对肺炎克雷伯菌的抗生素耐药药物 | Jin, L. | N/A | Deep Learning with Evolutionary Scale Modeling to discover Antibiotic-Resistance Drug against Klebsiella Pneumoniae | |
| Diverse-Seq：一种用于无对齐选择和聚类生物序列的应用程序 | Huttley, G. A. | N/A | diverse-seq: an application for alignment-free selecting and clustering biological sequences | |
| 通过局部治疗克服乳腺癌耐药性的多靶点天然配体及高效siRNA设计的计算机发现 | Hashemi, S. M. J. | N/A | In Silico Discovery of Multi-Target Natural Ligands and Efficient siRNA Design for Overcoming Drug Resistance in Breast Cancer via Local Therapy | |
| ROSIE：从组织病理学图像生成多重免疫荧光染色的人工智能技术 | Wu, E. | N/A | ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images | |
| CYP2E1对肾脏的性别依赖性影响及4MP对顺铂诱导肾毒性的保护潜力 | Akakpo, J. Y. | N/A | Sex-dependent effects of CYP2E1 on the kidney and the protective potential of 4MP against cisplatin-induced nephrotoxicity | |
| 根木质部面积通过土壤质地依赖的方式影响珍珠粟的耐旱性和蒸腾作用 | Affortit, P. | N/A | Root metaxylem area influences drought tolerance and transpiration in pearl millet in a soil texture dependent manner | |
| 聚苯乙烯纳米塑料通过催化TDP43的过度磷酸化促进神经退行性变。 | Winanto, W. | N/A | Polystyrene nanoplastics promote neurodegeneration by catalyzing TDP43 hyperphosphorylation | |
| 基底节颤抖症中丘脑、小脑和运动皮层之间的振荡耦合 | Steina, A. | N/A | Oscillatory coupling between thalamus, cerebellum and motor cortex in essential tremor | |
| 以少胜多：基于模拟的推断使得在极短的采集时间内也能获得准确的扩散加权磁共振成像 | Eggl, M. F. | N/A | More with less: Simulation-based inference enables accurate diffusion-weighted MRI with minimal acquisition time | |
| 持续的感觉运动转换增强了猕猴运动皮层神经动力学对扰动的鲁棒性 | Cui, H. | N/A | Continuous sensorimotor transformation enhances robustness of neural dynamics to perturbation in macaque motor cortex | |
| 人类对基因减毒疟原虫的相关体液和细胞免疫 | Colstrup, E. | N/A | Correlative humoral and cellular immunity to genetically attenuated malaria parasites in humans | |
| 一种调节因子在莫拉氏菌科中同时调控DNA损伤应答与抗噬菌体防御网络 | Song, S. | N/A | A regulator controls both DNA damage response and anti-phage defense networks in Moraxellaceae | |
| 卵母细胞中CDK12的缺失导致女性不孕 | Jansova, D. | N/A | Absence of CDK12 in oocyte leads to female infertility | |
| SARS-CoV-2 BA.2.86变异株及其亚系在刺突蛋白中对赖氨酸的偏好增加，而对精氨酸的偏好减少。 | Bozic, A. | N/A | Increased preference for lysine over arginine in spike proteins of SARS-CoV-2 BA.2.86 variant and its sublineages | |
| Src抑制对人类膀胱癌临床前模型中转移决定因素的异质性效应 | Aragaki, K. | N/A | Heterogeneous Effects of Src Inhibition on Determinants of Metastasis in Preclinical Models of Human Bladder Cancer | |
| ELOVL6作为治疗靶点：破坏c-MYC驱动的脂质代谢以增强胰腺癌化疗 | Garcia Garcia, A. | N/A | ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer | |
| 活细胞磁性显微操作回收内体揭示其对促进侵袭性迁移的肌动蛋白基突起的直接影响 | Gemperle, J. | N/A | Live-cell magnetic micromanipulation of recycling endosomes reveals their direct effect on actin-based protrusions to promote invasive migration | |
| 心脏修复中纤维化生态位的时空动力学 | Grün, D. | N/A | Spatio-temporal dynamics of the fibrotic niche in cardiac repair | |
| 家蚕茧的抗刺穿性能 | Rehman, A. U. | N/A | The stab resistance of Bombyx mori silk cocoons | |
| 新发现的脊椎动物早期抗病毒感染中IgM的保守作用 | Kong, W. | N/A | Newly discovered and conserved role of IgM against viral infection in an early vertebrate | |
| 胆固醇代谢与结核分枝杆菌内部的钾离子稳态之间存在内在关联。 | Chen, Y. | N/A | Cholesterol metabolism and intrabacterial potassium homeostasis are intrinsically related in Mycobacterium tuberculosis | |
| 用于研究COVID感染后遗症的适应小鼠的SARS-CoV-2模型 | Zhao, Z. | N/A | A Mouse-adapted SARS-CoV-2 Model for Investigating Post-acute Sequelae of COVID infection | |
| 模拟近海油田环境：双厌氧生物膜反应器对微生物诱导腐蚀的见解 | Jones, L. M. | N/A | Simulating Offshore Oilfield Conditions: Insights into Microbiologically Influenced Corrosion from a Dual Anaerobic Biofilm Reactor | |
| 在细胞间传播过程中，志贺氏菌（Shigella flexneri）需要一个具有易位能力的孔道来逃逸双层膜液泡。 | Raab, J. E. | N/A | A translocation-competent pore is required for Shigella flexneri to escape from the double membrane vacuole during intercellular spread | |
| 微管结合诱导了动力蛋白-1中一种类似于Mg-free的ADP预释放构象，这种构象不受其自抑制尾的影响。 | Atherton, J. | N/A | Microtubule association induces a Mg-free apo-like ADP pre-release conformation in kinesin-1 that is unaffected by its autoinhibitory tail | |
| 食品级植物抗氧化剂配方抑制肌红蛋白氧化 | Vergara-Stange, V. | N/A | Inhibition of Myoglobin Oxidation by Food Grade Botanical Antioxidant Formulations | |
| UniOP：一种利用基因间距离对高通量原核生物（元）基因组数据进行通用操纵子预测的方法 | Su, H. | N/A | UniOP: a universal operon prediction for high-throughput prokaryotic (meta-)genomic data using intergenic distance | |
| AlphaBind，一种特定领域的模型，用于预测和优化抗体-抗原结合亲和力 | Agarwal, A. A. | N/A | AlphaBind, a Domain-Specific Model to Predict and Optimize Antibody-Antigen Binding Affinity | |
| 使用条件最优传输在单细胞水平建模CAR响应 | Driessen, A. | N/A | Modeling CAR Response at the Single-Cell Level Using Conditional Optimal Transport | |
| 从人诱导多能干细胞生成形态不同的星形胶质细胞亚型揭示了胶质形态、功能和反应性之间的联系 | O'Toole, K. | N/A | Generation of morphologically distinct astrocyte subtypes from human iPSCs reveals a link between glial shape, function and reactivity | |
| 极光激酶A通过调节内源性S-腺苷甲硫氨酸代谢促进训练免疫 | Li, M. | N/A | Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism | |
| 单分子成像技术在T细胞转录动力学、RNA定位及命运研究中的应用 | Lattanzio, M. V. | N/A | Single molecule imaging of transcription dynamics, RNA localization and fate in T cells | |
| 比较基因组学揭示粘细菌碳水化合物降解潜力及其生态影响。 | Saraf, N. | N/A | Comparative genomic insight into the myxobacterial carbohydrate-degrading potential and their ecological impact. | |
| 抗病毒抗性进化揭示了基孔肯雅病毒包膜糖蛋白之间短暂的跨域功能相互作用 | Battini, L. | N/A | Evolution of antiviral resistance captures a transient interdomain functional interaction between chikungunya virus envelope glycoproteins | |
| 在半高通量分析中评估青蒿素治疗后恶性疟原虫的生长、抗性和恢复情况 | Sievert, M. A. | N/A | Measuring Growth, Resistance and Recovery after Artemisinin Treatment of Plasmodium falciparum in a semi-high-throughput Assay | |
| 乙醇胺诱导的微隔室组装是具核梭杆菌毒力所必需的 | Franklin, D. | N/A | Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence | |
| 解析关键分类单元：门多塔湖微生物网络内的相互作用及环境动态 | Yang, Q. | N/A | Unraveling Keystone Taxa: Interactions Within Microbial Networks and Environmental Dynamics in Lake Mendota | |
| NLRP1 被棕榈酸激活，并在人类代谢功能障碍相关性脂肪性肝炎中被诱导。 | Pinilla, M. | N/A | NLRP1 is activated by palmitic acid and induced in human metabolic dysfunction-associated steatohepatitis | |
| 在卵子发生和早期胚胎发生过程中对bicoid mRNA的调控影响蛋白质梯度的形成。 | Athilingam, T. | N/A | Regulation of bicoid mRNA throughout oogenesis and early embryogenesis impacts protein gradient formation | |
| 毛里求斯果蝇中交叉分布的模式需要重新思考着丝粒对交叉的影响 | Hawley, R. S. | N/A | Patterns of crossover distribution in Drosophila mauritiana necessitate a re-thinking of the centromere effect on crossing over | |
| U1 snRNP特异性蛋白U1C在snRNP生物发生中充当运动神经元生存（SMN）复合体的守门员 | Ngu, D. M. | N/A | U1 snRNP-Specific U1C Acts as the Gatekeeper of the Survival of Motor Neurons (SMN) Complex in snRNP Biogenesis | |
| 通过定制的CRISPR-Cas9碱基编辑器治疗体内严重的血管疾病 | Alves, C. R. R. | N/A | In vivo Treatment of a Severe Vascular Disease via a Bespoke CRISPR-Cas9 Base Editor | |
| 负链RNA病毒中的转录梯度提示了一种共同的RNA转录机制 | King, C. R. | N/A | The Transcriptional Gradient in Negative-Strand RNA Viruses Suggests a Common RNA Transcription Mechanism | |
| 升高的I型干扰素信号定义了ARF和p53突变肿瘤细胞的增殖优势 | Mabry, A. | N/A | Elevated type I interferon signaling defines the proliferative advantage of ARF and p53 mutant tumor cells | |
| Elovl1抑制减少了肾上腺脑白质营养不良小鼠模型中的极长链脂肪酸。 | Huang, J. | N/A | Elovl1 inhibition reduced very long chain fatty acids in a mouse model of adrenoleukodystrophy | |
| MdMPK6/02G介导的MdWRKY70L磷酸化调控活性氧合成以调节苹果果实衰老 | Wang, H. | N/A | Phosphorylation of MdWRKY70L by MdMPK6/02G mediates reactive oxygen synthesis to regulate apple fruit senescence | |
| 自然语言提示指导新型功能性蛋白质序列的设计 | Praljak, N. | N/A | Natural Language Prompts Guide the Design of Novel Functional Protein Sequences | |
| 固定石蜡包埋活检的单细胞空间转录组学揭示了与结肠炎相关的细胞网络 | Mennillo, E. | N/A | Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies reveals colitis-associated cell networks | |
| 艰难梭菌的抗菌药物敏感性测试：一项针对三种不同培养基和三种治疗性抗菌药物的双中心研究 | Freeman, J. | N/A | Antimicrobial susceptibility testing of Clostridioides difficile: a dual-site study of three different media and three therapeutic antimicrobials | |
| 构象变化、过剩面积及Piezo蛋白-膜纳米穹顶的弹性：来自粗粒化和原子模拟的研究 | Dixit, S. | N/A | Conformational changes, excess area, and elasticity of the Piezo protein-membrane nanodome from coarse-grained and atomistic simulations | |
| 共享住宅庭院中的生物多样性潜力 | Livne, H. | N/A | Potential for Biodiversity in Shared Residential Yards | |
| 适应性蛋白质协同进化保持端粒完整性 | Futeran, H. | N/A | Adaptive protein coevolution preserves telomere integrity | |
| 全面评估AlphaFold-Multimer、AlphaFold3和ColabFold在预测蛋白质-肽复合物结构中的表现及评分函数 | Manshour, N. | N/A | Comprehensive Evaluation of AlphaFold-Multimer, AlphaFold3 and ColabFold, and Scoring Functions in Predicting Protein-Peptide Complex Structures | |
| 在慢性病毒感染小鼠期间，凝血酶原可预防致命的T细胞依赖性贫血 | Cantrell, R. | N/A | Prothrombin prevents fatal T cell-dependent anemia during chronic virus infection of mice | |
| 饥饿通过抑制纹状体尾部多巴胺信号来调节探索行为 | Kamath, T. | N/A | Hunger modulates exploration through suppression of dopamine signaling in the tail of striatum | |
| 扩展杏仁核促肾上腺皮质激素释放激素神经元调控草原田鼠（Microtus ochrogaster）在社会挫败后配对结合形成的性别二态性变化 | Tickerhoof, M. C. | N/A | Extended amygdala corticotropin-releasing hormone neurons regulate sexually dimorphic changes in pair bond formation following social defeat in prairie voles (Microtus ochrogaster) | |
| 呼吸网络中的非对称神经调制有助于节律和模式的生成。 | Dhingra, R. R. | N/A | Asymmetric neuromodulation in the respiratory network contributes to rhythm and pattern generation | |
| 来自CDKL5缺陷症患者来源的皮质兴奋性神经元在早期表现出过度兴奋性，而这种过度兴奋性在由Neurogenin2诱导的神经元中未被发现。 | Glass, M. R. | N/A | Excitatory Cortical Neurons from CDKL5 Deficiency Disorder Patient-Derived Organoids Show Early Hyperexcitability Not Identified in Neurogenin2 Induced Neurons | |
| 对性别偏向选择反应的表达分歧 | Grieshop, K. | N/A | Expression divergence in response to sex-biased selection | |
| 中性粒细胞胞外陷阱促进肿瘤对蒽环类药物的化学耐药性 | Lin, C. | N/A | Neutrophil extracellular traps promote tumor chemoresistance to anthracyclines | |
| 线粒体相关内质网膜对胆固醇稳态的贡献 | Montesinos, J. | N/A | The contribution of mitochondria-associated ER membranes to cholesterol homeostasis | |
| # BioRxiv 2024-11-10 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 地方志揭示了中国东部顶级捕食者和中型捕食者历史分布变化的对比模式 | Hu, K. | N/A | Local Gazetteers Reveal Contrasting Patterns of Historical Distribution Changes between Apex Predators and Mesopredators in Eastern China | |
| 人乳头瘤病毒的非网格蛋白依赖性内吞作用由肌动蛋白成核促进因子WASH辅助完成。 | Brinkert, P. | N/A | Clathrin-independent endocytosis of Human Papillomaviruses is facilitated by actin nucleation promoting factor WASH | |
| 排列匹配测试：尽管存在非平稳性和有限重复，仍能检测时间序列之间显著相关性的方法 | Yuan, A. E. | N/A | Permute-match tests: Detecting significant correlations between time series despite nonstationarity and limited replicates | |
| 基于纳米孔测序的多重PCR检测四种罗非鱼病原体的序列分析 | Delamare-Deboutteville, J. | N/A | Multiplex PCR with Nanopore Sequencing for Sequence-Based Detection of Four Tilapia Pathogens | |
| 马寄生虫中数量最多的Cylicocyclus nassatus对吡喹酮抗性的时空多样性和遗传结构 | Salle, G. | N/A | Spatio-temporal diversity and genetic architecture of pyrantel resistance in Cylicocyclus nassatus, the most abundant horse parasite | |
| 系统分析无义变异揭示了肽释放速率作为无义介导的mRNA衰变的新型修饰因子 | Kolakada, D. | N/A | Systematic analysis of nonsense variants uncovers peptide release rate as a novel modifier of nonsense-mediated mRNA decay | |
| 在霍乱弧菌中，MatP局部富集延迟了分离，与四聚体形成和隔膜锚定无关。 | Espinosa, E. | N/A | MatP local enrichment delays segregation independently of tetramer formation and septal anchoring in Vibrio cholerae | |
| Celldetective：一种利用人工智能增强的图像分析工具，用于揭示动态细胞相互作用 | Torro, R. | N/A | Celldetective: an AI-enhanced image analysis toolfor unraveling dynamic cell interactions | |
| 贝叶斯选择松弛时钟模型：区分独立和自相关速率 | Panchaksaram, M. | N/A | Bayesian Selection of Relaxed-clock Models:Distinguishing Between Independent and Autocorrelated Rates | |
| 棉铃虫通过储存和释放挥发性物质，在野生棉花（Gossypium hirsutum）种群中诱导出不同的萜烯化学型。 | Mamin, M. | N/A | Induction by caterpillars of stored and emitted volatiles in terpene chemotypes from populations of wild cotton (Gossypium hirsutum) | |
| 牺牲适应性以换取功能性：视网膜Müller细胞的象牙塔 | Zhang, T. | N/A | Sacrificing Adaptability for Functionality: The Ivory Tower of Macular Muller Cells | |
| 预测高度灵活、变构、多结构域蛋白质中的结合事件 | Basciu, A. | N/A | Predicting binding events in very flexible, allosteric, multi-domain proteins | |
| 基于能量的葡萄糖运输的键图模型，涉及SLC转运蛋白 | Hunter, P. J. | N/A | Energy-based bond graph models of glucose transport with SLC transporters | |
| 小鼠防御素基因座中的遗传变异调节血糖稳态 | Masson, S. W. W. | N/A | Genetic variance in the murine defensin locus modulates glucose homeostasis | |
| 产前高膳食钙补充对奶羊和奶山羊钙和骨稳态及其后代生长反应的影响 | Brugger, D. | N/A | High dietary calcium supplementation ante partum and effects on calcium and bone homeostasis of dairy sheep and goats and growth response of their offspring | |
| 发现了一种单亚基寡糖基转移酶，使大肠杆菌中全长IgG抗体的糖基化成为可能 | Sotomayor, B. | N/A | Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in Escherichia coli | |
| CA3中的选择性抑制：通过异源突触可塑性实现稳定模式完成的机制 | Kim, G. | N/A | Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity | |
| 基准测试用于DNA结合蛋白识别的最新计算工具 | Luo, X. | N/A | Benchmarking Recent Computational Tools for DNA-binding Protein Identification | |
| Robinow综合征DVL1变异体在果蝇疾病模型中破坏形态发生和附肢形成 | Akarsu, G. | N/A | Robinow Syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model | |
| 生物工程改造一种常见的益生菌以利用结肠炎症，在炎症性肠病的转化模型中促进了可靠的疗效 | Verdugo Meza, A. | N/A | Bio-engineering a common probiotic to exploit colonic inflammation promotes reliable efficacy in translational models of colitis | |
| 体内功能分析与人类Glp1r A316T变异体的结构表征 | El Eid, L. | N/A | In vivo functional profiling and structural characterisation of the human Glp1r A316T variant | |
| 通过空间蛋白质组学揭示初级纤毛的内在多样性 | Hansen, J. N. | N/A | Intrinsic Diversity In Primary Cilia Revealed Through Spatial Proteomics | |
| 全面的蛋白酶特异性分析 | Zhu, B. | N/A | Comprehensive protease specificity profiling | |
| 一种共识变异-功能评分，用于为疾病功能性地优先考虑变异 | Fabiha, T. | N/A | A consensus variant-to-function score to functionally prioritize variants for disease | |
| 光遗传学杏仁核中央核刺激在雄性大鼠中具有高度强化作用，并且显著优于芬太尼自我给药，但在雌性大鼠中则不然。 | Chaloux-Pinette, E. | N/A | Optogenetic Central Amygdala Stimulation is Highly Reinforcing and Strongly Outcompetes Fentanyl Self-Administration in Male, but not Female, Rats | |
| 将脑信号建模为马尔可夫过程有助于解释其结构与功能之间的关系。 | Razban, R. | N/A | Modeling brain signaling as Markovian helps explain its structure-function relationship | |
| 使用基于连接组预测建模方法，直接比较静息态和任务态脑电图功能连接模式对工作记忆表现的预测能力。 | Pashkov, A. A. | N/A | Direct comparison of EEG resting state and task functional connectivity patterns for predicting working memory performance using connectome-based predictive modeling | |
| 时间队列编号、神经元组成和连接性沿果蝇幼虫体轴有所变化。 | Vasudevan, D. | N/A | Temporal cohort number, neural composition, and connectivity vary along the Drosophila larval body axis | |
| TiFM2.0 - 在活体胚胎中实现多功能的机械测量与驱动 | Hernandez-Rodriguez, A. R. | N/A | TiFM2.0 - Versatile mechanical measurement and actuation in live embryos | |
| 单细胞与空间多组学揭示干扰素信号在肛周瘘管性克罗恩病发病机制中的作用 | Cao, S. | N/A | Single-Cell and Spatial Multi-omics Reveal Interferon Signaling in the Pathogenesis of Perianal Fistulizing Crohn's Disease | |
| Grin2a功能低下破坏了海马网络振荡和E/I平衡，进而导致认知缺陷。 | Hosseini, H. S. | N/A | Grin2a Hypofunction Disrupts Hippocampal Network Oscillations and E/I Balance Contributing to Cognitive Deficits | |
| 利用针对阿尔茨海默病治疗的校正剂重新编程神经元的分泌和代谢机制 | Cho, W. J. | N/A | Reprogramming the neuronal secretory and metabolic machinery using correctors for Alzheimer therapy | |
| 中国阴道微生物群的地理特异性多样化 | Yang, H. | N/A | Geographic-specific Diversification of Vaginal Microbiota in China | |
| 药品的环境影响：近期关于水生浓度及可预测效应的证据映射综述 | Renda, F. | N/A | The environmental impact of pharmaceuticals: an evidence-mapping review of recent data on aquatic concentrations and predictable effects | |
| 东南亚厄尔尼诺驱动的干旱、火灾和烟雾对非人类灵长类动物影响的综合评述 | Erb, W. M. | N/A | A Systematic Review of the Impacts of El Nino-Driven Drought, Fire, and Smoke on Non-Human Primates in Southeast Asia | |
| Tidyplots 使生命科学家能够通过简单的代码实现数据可视化。 | Engler, J. B. | N/A | Tidyplots empowers life scientists with easy code-based data visualization | |
| 三阴性乳腺癌患者远处转移的风险因素、预后因素及诺模图：一项基于人群的研究 | Guo, H. | N/A | Risk factors, prognostic factors, and nomograms for distant metastasis in patients with triple-negative breast cancer: a population-based study | |
| 在直肠癌患者中，上皮间质转化（Epithelial Mesenchymal Transition, EMT）的形态分子特征与临床预后相关。 | Gwerder, M. | N/A | Morpho-molecular features of Epithelial Mesenchymal Transition associate with clinical outcome in patients with rectal cancer | |
| 卒中和运动恢复与周期性和非周期性皮层活动的区域性和年龄特异性变化有关 | Albertson, A. J. | N/A | Stroke and Motor Recovery are Associated with Regional and Age-Specific Changes in Periodic and Aperiodic Cortical Activity | |
| 生成用于SARS-CoV-2复制子传递颗粒感染的生物安全小鼠模型 | Li, Y. | N/A | Generation of a biosafety mouse model infection for SARS-CoV-2 replicon delivery particles | |
| 西北大西洋中B族维生素和钴胺素共同限制的季节性模式 | Bannon, C. C. | N/A | Seasonal patterns in b-vitamins and cobalamin co-limitation in the Northwest Atlantic | |
| 利用CRISPR-Cas9技术对硅藻浮游生物中单细胞微生物群进行分析，以鉴定稀有细菌类群 | Giesler, J. K. | N/A | A CRISPR-Cas9 assisted analysis of single-cell microbiomes for identifying rare bacterial taxa in phycospheres of diatoms | |
| 在HSV-1感染的细胞中，pUL16和pUL21的同时缺失会导致细胞质包膜形成的中断。 | Roddy, K. | N/A | The loss of both pUL16 and pUL21 in HSV-1 infected cells abolishes cytoplasmic envelopment. | |
| Pemivibart对SARS-CoV-2 JN.1亚系的灭活作用及其病毒逃逸 | Yao, T. | N/A | Neutralizing Activity and Viral Escape of Pemivibart by SARS-CoV-2 JN.1 sublineages | |
| 从随机序列中模拟球状蛋白质折叠的进化过程 | Sahakyan, H. | N/A | In silico evolution of globular protein folds from random sequences | |
| 在濒临灭绝的鹦鹉中，基因组范围和免疫基因多样性的暂时丧失 | Silver, L. W. | N/A | Temporal loss of genome-wide and immunogenetic diversity in a near-extinct parrot | |
| 提高了有序双模板中继cDNA文库制备在RNA测序中的精确度、灵敏度和适应性 | Ferguson, L. | N/A | Improved precision, sensitivity, and adaptability of Ordered Two-Template Relay cDNA library preparation for RNA sequencing | |
| Pfs230 域 12 是一种强效的疟疾传播阻断疫苗候选物。 | Inklaar, M. R. | N/A | Pfs230 Domain 12 is a potent malaria transmission-blocking vaccine candidate | |
| 复苏促进因子（Rpf）终止了多种土壤细菌的休眠状态。 | Lennon, J. T. | N/A | Resuscitation-promoting factor (Rpf) terminates dormancy among diverse soil bacteria | |
| 通过福尔马林反应降解非生物合成四碳糖的细菌的分离 | Kawasaki, K. | N/A | Isolation of bacteria that catabolize abiotically synthesized tetroses via the formose reaction | |
| 利用生成语言模型从头设计磷酸丙糖异构酶 | Romero-Romero, S. | N/A | De novo design of triosephosphate isomerases using generative language models | |
| 双酶抑制策略治疗2型糖尿病：以黄酮-阿卡波糖组合靶向LDH-A和α-淀粉酶 | Gupta, S. | N/A | Dual Enzyme Inhibition Strategy for Type 2 Diabetes: Targeting LDH-A and α-Amylase with Flavonoid-Acarbose Combinations | |
| AlphaFold-Metainference：无序蛋白质结构集合的预测 | Brotzakis, Z. F. | N/A | AlphaFold-Metainference: Prediction of Structural Ensembles of Disordered Proteins | |
| 海洋光合作用直接受到噬藻体NblA蛋白的影响。 | Beja, O. | N/A | Oceanic photosynthesis is directly affected by cyanophage NblA proteins | |
| 卟啉单胞菌的基因组多样性：卟啉单胞菌猫属共生在肺部的证据 | VELO-SUAREZ, L. | N/A | Genomic Diversity in Porphyromonas: Evidence of Porphyromonas catoniae Commensality in Lungs | |
| ComFB是一种新近广泛分布的环二核苷酸受体蛋白家族 | Samir, S. | N/A | ComFB, a new widespread family of c-di-NMP receptor proteins | |
| 在铁充足、铁缺乏和铁替代状态下，血浆和心肌中铁状态生物标志物的不一致性。 | Tomkova, K. | N/A | Discordance between biomarkers of iron status in plasma and myocardium across iron replete, iron deficiency, and iron replacement states. | |
| 氟喹诺酮类药物依诺沙星的抗HIV-1作用及对前病毒hsa-miR-132加工的调控 | Imig, J. | N/A | Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-viral hsa-miR-132 Processing | |
| 翻译校对过程中产生的同型半胱氨酸硫内酯是一种内源性配体，通过受体SdiA进行细胞间信号传导。 | Leiva, L. E. | N/A | Homocysteine thiolactone from translation proofreading is an endogenous ligand for cell-cell signaling by the receptor SdiA | |
| 对非洲乳菇属（Russula）的拉丁根亚属（radicans）及其近缘类群在异叶亚属（Heterophyllidiae）中的修订，提供了一个近期分化且具有广泛表型可塑性的进化枝的实例。 | Buyck, B. | N/A | A revision of the African Russula radicans and allies in subgen. Heterophyllidiae provides an example of a clade that exhibits recent diversification and extensive phenotypic plasticity. | |
| AI辅助的本地蛋白质组学：描绘核糖体蛋白组装前后的构象 | Zhang, W. | N/A | AI Assisted Native Proteomics: Delineating Ribosomal Protein Conformations Pre- and Post-Assembly | |
| 鉴定出一群在骨关节炎大鼠模型中具有增强治疗效果的滑膜间充质干细胞亚群 | Al_Jezani, N. | N/A | Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of Osteoarthritis | |
| 通过REDCAT实现单细胞类型特异性代谢活性的全光多模态映射 | Shi, L. | N/A | All-Optical Multimodal Mapping of Single Cell Type-Specific Metabolic Activities via REDCAT | |
| 烃类化合物对乳腺癌肿瘤性和非肿瘤性细胞存活及抗氧化系统的影响。 | Mardirosian, M. N. | N/A | Hydrocarbon effects on cell survival and antioxidant system of breast tumorigenic and non-tumorigenic cells. | |
| 细胞质长链非编码RNA（lncRNAs）启动信号通路，以定义亚稳态动力学并决定表型输出。 | PORTAL, M. M. | N/A | Cytoplasmic lncRNAs nucleate signalling pathways to define metastable state dynamics and determine phenotypic output | |
| 无标记显微镜图像中细胞环境依赖的计算机模拟细胞器定位 | Elmalam, N. | N/A | Cell-context dependent in silico organelle localization in label-free microscopy images | |
| M1连接的泛素化通过LUBAC调控AMPK活性及对能量应激的响应 | Elbaek, C. R. | N/A | M1-linked Ubiquitination by LUBAC Regulates AMPK Activity and the Response to Energetic Stress | |
| 小GTPase Rap1与哺乳动物肿瘤抑制蛋白同源物KrsB之间的负反馈回路调节了Dictyostelium中的细胞-基质粘附。 | Artemenko, Y. | N/A | A negative feedback loop between small GTPase Rap1 and mammalian tumor suppressor homolog KrsB regulates cell-substrate adhesion in Dictyostelium | |
| TXNL1结合的蛋白酶体结构 | Gao, J. | N/A | Structure of the TXNL1-bound proteasome | |
| 减少功能缺陷的造血干细胞可缓解老年小鼠的衰老相关表型 | Zhang, Y. | N/A | Reducing functionally defective HSCs alleviates aging-related phenotypes in old mice | |
| # BioRxiv 2024-11-09 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 序列和化学特异性定义了固有无序区域的功能景观 | Langstein-Skora, I. | N/A | Sequence- and chemical specificity define the functional landscape of intrinsically disordered regions | |
| 一种校正转录组关联研究中预测表达不确定性的方法 | Majumdar, A. | N/A | A method to adjust for the uncertainty of predicted expression in transcriptome-wide association study | |
| DnaB-复制解旋酶-噬菌体{lambda}P装载复合物的自抑制构象 | Brown, D. | N/A | An Autoinhibited Conformation of the DnaB-Replicative Helicase - phage {lambda}P Loader Complex | |
| 探究数学学习困难儿童的前额叶-顶叶网络及激活情况：不同缺陷特征的案例研究 | Wang, F. | N/A | Investigating Frontoparietal Networks and Activation in Children with Mathematics Learning Difficulties: Cases with Different Deficit Profiles | |
| 小脑浦肯野细胞控制斑马鱼（Danio rerio）幼体的姿势 | Auer, F. | N/A | Cerebellar Purkinje Cells Control Posture in Larval Zebrafish (Danio rerio) | |
| 种群大小与生殖寿命相互作用，共同塑造了种系突变率。 | Zhu, L. | N/A | Population size interacts with reproductive longevity to shape the germline mutation rate | |
| 未配对和异质性临床流式细胞术数据的整合 | Phuycharoen, M. | N/A | Integration of Unpaired and Heterogeneous Clinical Flow Cytometry Data | |
| 组合预训练提高了计算效率，并在复杂任务上与动物行为相匹配。 | Hocker, D. L. | N/A | Compositional pretraining improves computational efficiency and matches animal behavior on complex tasks | |
| 通过随机连接的前馈网络中的树突计算来区分神经集合模式 | Somashekar, B. P. | N/A | Discriminating neural ensemble patterns through dendritic computations in randomly connected feedforward networks | |
| HistoGWAS：一种用于组织学队列中组织表型自动化遗传分析的AI驱动框架 | Chaudhary, S. | N/A | HistoGWAS: An AI-enabled Framework for Automated Genetic Analysis of Tissue Phenotypes in Histology Cohorts | |
| 新热带生物多样性指标的基因组学：两种蝴蝶辐射具有猖獗的染色体重排和杂交现象 | van der Heijden, E. S. | N/A | Genomics of Neotropical biodiversity indicators: two butterfly radiations with rampant chromosomal rearrangements and hybridisation | |
| 质心工作组件可能为任何行走条件下的首选行走速度提供估计 | Hosseini-Yazdi, S.-S. | N/A | Center of Mass Work Components May Offer Estimates for Preferred Walking Speeds for Any Walking Conditions | |
| 线粒体直接重复序列减少作为增强人类长寿的策略：常见重复序列的案例 | Shamanskiy, V. A. | N/A | Mitochondrial direct repeat reduction as a strategy for enhancing human longevity: the case of the common repeat | |
| 空间转录组学基因表示框架 | Cao, S. | N/A | A framework for gene representation on spatial transcriptomics | |
| 少突胶质细胞利用突触后蛋白来协调在不同神经递质类别轴突上的髓鞘形成。 | Carey, N. | N/A | Oligodendrocytes use post-synaptic proteins to coordinate myelin formation on axons of distinct neurotransmitter classes | |
| 解码空间组织结构：一种可扩展的多重成像分析贝叶斯主题模型 | Peng, X. | N/A | Decoding Spatial Tissue Architecture: A Scalable Bayesian Topic Model for Multiplexed Imaging Analysis | |
| MMP21作为一种流体流动输送的形态发生素，在发育过程中赋予生物体左右对称性。 | Ott, T. | N/A | MMP21 behaves as a fluid flow transported morphogen to impart laterality during development | |
| 冰川消退后，全浮游栉水母Mnemiopsis的快速物种形成 | Ketchum, R. N. | N/A | Rapid speciation in the holopelagic ctenophore Mnemiopsis following glacial recession | |
| FoldMark：通过水印技术保护蛋白质生成模型 | ZHANG, Z. | N/A | FoldMark: Protecting Protein Generative Models with Watermarking | |
| 细胞类型特异性表观基因组编辑在发育中的小鼠皮层中促进中间祖细胞增殖，通过在lncSox1启动子处靶向H3K9乙酰化 | Sokpor, G. | N/A | Targeted H3K9 acetylation at lncSox1 promoter by cell type-specific epigenome editing promotes intermediate progenitor proliferation in developing mouse cortex | |
| 使用PANDORA进行MHC II类分子的双向肽构象预测 | Rademaker, D. T. | N/A | Bidirectional Peptide Conformation Prediction for MHC Class II using PANDORA | |
| 建模溶瘤痘苗病毒疗法突显了中性粒细胞对肿瘤抑制的影响 | Satani, S. | N/A | Modeling Oncolytic Vaccinia Virus Therapy Highlights Neutrophil Impact on Tumor Suppression | |
| OsMORF蛋白特异性地促进双定位RNA编辑因子OsPGL1与其目标RNA的结合。 | Xiao, H. | N/A | OsMORF protein selectively promotes the dual-localized RNA editing factor OsPGL1 binding to its target RNA | |
| RBPMS和RBPMS2协同作用以保护心脏剪接 | Wu, T. | N/A | RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing | |
| 比较留尼汪岛上的白纹伊蚊和致倦库蚊的病毒群落 | Francois, S. | N/A | Contrasted viral communities between Aedes albopictus and Culex quinquefasciatus in La Reunion Island | |
| 一种多价适配机制驱动蛋白酶体的核输入 | Brunner, H. L. | N/A | A multivalent adaptor mechanism drives the nuclear import of proteasomes | |
| 早发性骨关节炎诱导的COL2A1 p.Arg719Cys人类软骨模型揭示了病理驱动性基质缺陷及内质网蛋白质稳态网络未能识别缺陷型前胶原-II | Yammine, K. M. | N/A | Human cartilage model of the precocious osteoarthritis-inducing COL2A1 p.Arg719Cys reveals pathology-driving matrix defects and a failure of the ER proteostasis network to recognize the defective procollagen-II | |
| 细胞命运决定与人类GATA1和GATA2谱系决定转录因子中竞争性转录单元的变化相关联。 | Anderson, E. M. | N/A | Cell fate determination is associated with changes in competing transcriptional units in the human GATA1 and GATA2 lineage-determining transcription factors | |
| 对具有多个等位基因的位点进行选择的综合表示，允许复杂的基因型适应性形式 | Vellnow, N. | N/A | A comprehensive representation of selection at loci with multiple alleles that allows complex forms of genotypic fitness | |
| 小分子奥昔布宁可挽救复杂III缺陷型MPCs的增殖能力 | Qu, Y. | N/A | Small molecule oxybutynin rescues proliferative capacity of complex III-defective MPCs | |
| 从嗅球局部场电位推断呼吸节律的挑战 | Rafilson, S. E. | N/A | Challenges in inferring breathing rhythms from olfactory bulb local field potentials | |
| 针对促肾上腺皮质激素释放激素受体1型（CRHR1）神经元：验证新型转基因Crhr1-FlpO小鼠的特异性 | Hardy, M. | N/A | Targeting Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Neurons: Validating the Specificity of a Novel Transgenic Crhr1-FlpO Mouse | |
| 苍白球外侧部与皮层之间的投射涉及运动和非运动区域。 | Ferenczi, E. A. | N/A | Projections between the globus pallidus externa and cortex span motor and non-motor regions | |
| 通过单肽能神经元中频率依赖性递质切换编码对立效价 | Kim, D.-I. | N/A | Encoding opposing valences through frequency-dependent transmitter switching in single peptidergic neurons | |
| 双色外显子报告系统揭示了果蝇神经元中电压门控钙离子通道剪接异构体的多样性 | Macleod, G. T. | N/A | Bichromatic exon-reporters reveal voltage-gated Ca2+-channel splice-isoform diversity across Drosophila neurons in vivo | |
| 不同的脑电图预处理流程可能导致关于皮层兴奋/抑制比率的结论相互矛盾。 | Racz, F. S. | N/A | Alternative EEG pre-processing pipelines can lead to conflicting conclusions regarding cortical excitation/inhibition ratio | |
| 人脑中非周期性神经活动的发展 | Cross, Z. R. | N/A | The development of aperiodic neural activity in the human brain | |
| ERP和神经振荡能否用于区分生态有效运动模型中熟练和非熟练选手的表现？ | Winstanley, M. | N/A | Can ERPs and neural oscillations be used to differentiate skilled and unskilled player performance in an ecologically valid sporting model? | |
| 前扣带回神经元显示出与前额叶眼区的亚区特异性相互作用，这一发现是通过结合逆向刺激和静息态成像技术揭示的。 | Babapoor-Farrokhran, S. | N/A | Anterior cingulate neurons display subregion-specific interaction with frontal eye fields as revealed by combined antidromic stimulation and resting state imaging | |
| 中央杏仁核谷氨酸对降钙素基因相关肽反应的性别差异 | Lorsung, R. | N/A | Sex differences in central amygdala glutamate responses to calcitonin gene-related peptide | |
| 回顾性注意可以触发视觉感知，而不依赖于线索意识或目标报告。 | Li, Y. | N/A | Retrospective Attention Can Trigger Visual Perception Without Dependence on Either Cue Awareness or Target Reporting | |
| 经过训练自我给药可卡因或酒精的大鼠中，内侧前额叶皮质神经递质对促进复发和抑制复发的线索的反应 | Nedelescu, H. | N/A | Medial prefrontal cortical neurotransmitters reactive to relapse-promoting and relapse-suppressing cues in rats trained to self-administer cocaine or alcohol | |
| 循环事件的神经上下文恢复 | Broitman, A. W. | N/A | Neural Context Reinstatement of Recurring Events | |
| 一种整合了偏向竞争和强化学习的视觉注意力神经网络模型 | Morgan, J. M. | N/A | A Neural Network Model of Visual Attention Integrating Biased Competition and Reinforcement Learning | |
| 自然猪宿主中呼吸道冠状病毒的发病机制和免疫反应 | Sedaghat-Rostami, E. | N/A | Pathogenesis and immune response to respiratory coronaviruses in their natural porcine host | |
| 真菌感染风险条件下常用药物促进白色念珠菌耐药性或抗药性 | Obermeier, M. | N/A | Drugs Commonly Used in Fungal Infection Risk Conditions Promote Drug Tolerance or Resistance in Candida albicans | |
| Drospondin是一种新发现的由神经胶质细胞分泌的糖蛋白，它调控果蝇神经系统的发育和功能。 | Rojo-Cortes, F. | N/A | Drospondin, a novel glial-secreted glycoprotein, controls the development and function of the Drosophila nervous system | |
| 进化保守的DNA甲基化的遗传基础、定量性质及功能相关性 | Dong, Z. | N/A | Genetic Basis, Quantitative Nature, and Functional Relevance of Evolutionarily Conserved DNA Methylation | |
| 基于纳米孔检测DNA甲基化的工具综合基准测试 | Kulkarni, O. | N/A | Comprehensive benchmarking of tools for nanopore-based detection of DNA methylation | |
| 人类26S蛋白酶体中AAA+ ATP酶马达状态的结构景观揭示了TXNL1的构象特异性结合 | Martin, A. | N/A | Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1 | |
| DnaB 和 DciA：解旋酶在单链 DNA 上的装载和迁移机制 | Gao, N. | N/A | DnaB and DciA: Mechanisms of Helicase Loading and Translocation on ssDNA | |
| 植物γ-谷氨酰肽酶1的晶体结构及其在硫代谢中的双重作用和对氧化应激调控的启示 | Sone, K. | N/A | Crystal structure of plant γ-glutamyl peptidase 1 with dual roles in sulfur metabolism and implications for oxidative stress regulation | |
| 语言模型在原核生物中生成顺式调控元件 | Xia, Y. | N/A | Language model generates cis-regulatory elements across prokaryotes | |
| RIBOSS通过结合长读长和短读长转录组及翻译组分析，检测新的翻译事件。 | Lim, C. S. | N/A | RIBOSS detects novel translational events by combining long- and short-read transcriptome and translatome profiling | |
| 转化生长因子-β诱导的ERK和SMAD通路的计算建模与分析 | Chung, S. | N/A | Computational Modeling and Analysis of the TGF-β-induced ERK and SMAD Pathways | |
| 肠道粪肠球菌的易位通过C型凝集素受体Mincle训练骨髓髓系祖细胞 | Robles-Vera, I. | N/A | Translocation of gut Enterococcus faecalis trains myeloid bone marrow progenitors via the C-type lectin receptor Mincle | |
| 表型高通量筛选鉴定出肠道微生物胆碱代谢的调节因子 | Woo, A. Y. M. | N/A | Phenotypic high-throughput screening identifies modulators of gut microbial choline metabolism | |
| 原生动物和哺乳动物吞噬细胞对新生隐球菌吞噬反应的共性与差异表明，宿主细胞代谢是其在细胞内生存的目标。 | Dragotakes, Q. | N/A | Commonalities and differences in the Cryptococcus neoformans response to ingestion by protozoal and mammalian phagocytic cells suggests host cell metabolism as a target for intracellular survival | |
| 微生物差异能准确识别小鼠中的全球SERT KO表型 | Leitman, M. | N/A | Microbial Differences Accurately Identifies Global SERT KO Phenotype in Mice | |
| 评估未充分表征环境中的宏基因组分析：点亮微生物暗物质需要什么？ | Nickols, W. A. | N/A | Evaluating metagenomic analyses for undercharacterized environments: what's needed to light up the microbial dark matter? | |
| 从孙德尔本斯采集的银叶树根际中固氮细菌的分离、鉴定与鉴定 | Rimi, A. A. | N/A | Isolation, Characterization, and Identification of Nitrogen Fixing Bacteria from Rhizosphere of Sonneratia apetala Collected from Sundarbans | |
| 评估qPCR、dPCR和ddPCR在估算鸣禽血液和精子细胞中线粒体DNA拷贝数的可靠性和准确性 | Bagdonaite, L. | N/A | Assessing reliability and accuracy of qPCR, dPCR and ddPCR for estimating mtDNA copy number in songbird blood and sperm cells | |
| perilipin 5 磷酸化对于禁食状态下肝脏脂质代谢基因的上调并非必需，但在雄性小鼠中对胰岛素受体底物2的表达是必需的。 | Bovee, C. | N/A | Perilipin 5 Phosphorylation is Dispensable for Upregulation of Hepatic Lipid Metabolism Genes upon Fasting but Required for Insulin Receptor Substrate 2 Expression in Male Mice | |
| 在多物种背景下解构两种入侵者之间的适应性差异 | Freire, T. F. A. | N/A | Unpacking fitness differences between two invaders in a multispecies context | |
| 使用分子条形码进行精确谱系追踪显示了伊维菌素抗性在线虫中的适应性权衡 | Stevenson, Z. C. | N/A | Precise Lineage Tracking Using Molecular Barcodes Demonstrates Fitness Trade-offs for Ivermectin Resistance in Nematodes | |
| 一种共识的变异到功能评分，用于为疾病优先考虑功能变异 | Fabiha, T. | N/A | A consensus variant-to-function score to functionally prioritize variants for disease | |
| 新型组成型平滑肌细胞特异性Myh11驱动Cre小鼠模型的生成 | Dong, K. | N/A | Generation of a novel constitutive smooth muscle cell-specific Myh11-driven Cre mouse model | |
| TissueMosaic 通过自监督表示学习，实现了空间转录组学数据集的跨样本差异分析。 | Kambhampati, S. | N/A | TissueMosaic enables cross-sample differential analysis of spatial transcriptomics datasets through self-supervised representation learning | |
| 苯乙酸在陆地植物中的代谢：新途径与代谢物 | Hladik, P. | N/A | Phenylacetic acid metabolism in land plants: novel pathways and metabolites | |
| 使用噬菌体展示技术鉴定靶向蛋白质-蛋白质相互作用共价环状肽抑制剂的鉴定 | Wang, S. | N/A | Identification of Covalent Cyclic Peptide Inhibitors Targeting Protein-Protein Interactions Using Phage Display | |
| 类胡萝卜素色素通过光捕获和光循环加速，增强了视紫红质介导的光合作用。 | Fujiwara, T. | N/A | Carotenoid pigments enhance rhodopsin-mediated phototrophy by light-harvesting and photocycle-accelerating | |
| 一种细菌细胞壁修复和修饰系统，以抵抗宿主抗菌因子 | Burnier, J. | N/A | A bacterial cell wall repair and modification system to resist host antibacterial factors | |
| GpsB相关调节因子对PBP1a的表征揭示了肺炎链球菌细胞壁重塑复合体的组织结构 | Millat, H. | N/A | Characterization of a GpsB-associated regulator of PBP1a reveals the organization of the cell wall remodeling complex of Streptococcus pneumoniae | |
| 分子动力学模拟中蛋白质-脂质相互作用的驻留时间的贝叶斯非参数分析 | Sexton, R. C. | N/A | Bayesian nonparametric analysis of residence times for protein-lipid interactions in Molecular Dynamics simulations | |
| # BioRxiv 2024-11-08 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 模型化的网格细胞通过一个灵活的吸引子对齐 | Benas, S. | N/A | Modeled grid cells aligned by a flexible attractor | |
| 开发一种定量宏基因组学方法以建立定量限值及其在病毒中的应用 | Langenfeld, K. | N/A | Development of a quantitative metagenomic approach to establish quantitative limits and its application to viruses | |
| MAVISp：基于结构的蛋白质变体效应模块化框架 | Arnaudi, M. | N/A | MAVISp: A Modular Structure-Based Framework for Protein Variant Effects | |
| 详细描述了体内参与者和个体环挤压轨迹的影响 | Han, R. | N/A | Detailed in vivo characterization of the players and impact of individual loop extrusion trajectories | |
| 锥虫过氧化物酶体输入复合物的结构揭示了构象动力学 | Sonani, R. R. | N/A | Structure of Trypanosoma peroxisomal import complex unveils conformational dynamics | |
| 学习微生物组的深度语言模型：大规模未标记微生物组数据的力量 | Pope, Q. | N/A | Learning a deep language model for microbiomes: the power of large scale unlabeled microbiome data | |
| 厚组织的三维单细胞转录组成像 | Fang, R. | N/A | Three-dimensional single-cell transcriptome imaging of thick tissues | |
| 在高暴露人群中，独特的T细胞特征与减少的衣原体再感染相关 | Yount, K. S. | N/A | Unique T cell signatures associated with reduced Chlamydia trachomatis reinfection in a highly exposed cohort | |
| 上皮组织流变学的标度律 | Cheikh, M. I. | N/A | A scaling law for epithelial tissue rheology | |
| TgLaforin，一种葡聚糖磷酸酶，揭示了储存多糖在弓形虫速殖子和缓殖子中的动态作用。 | Murphy, R. D. | N/A | TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in Toxoplasma gondii tachyzoites and bradyzoites | |
| LRP1 在独立于 NMDA 受体的情况下，通过响应胞外 Tau 触发促炎细胞信号传导。 | Azmoon, P. | N/A | LRP1 Triggers Pro-inflammatory Cell-signaling in Response to Extracellular Tau Independently of the NMDA Receptor | |
| 基因和药物对claudin9水平的改变足以诱导功能性和成熟的内毛细胞 | Chen, Y. | N/A | Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells | |
| 评估两种近缘的Malurus细尾鹩莺物种中雌性攻击性与雄性表型之间的关系 | Jones, J. A. | N/A | Assessing the relationship between female aggression and male phenotype in two sister Malurus fairywren species | |
| 在动作执行和观察过程中，前运动皮质神经元之间的共调制模式逐渐变化，携带动态相似的信号。 | Zhao, Z. | N/A | Progressively shifting patterns of co-modulation among premotor cortex neurons carry dynamically similar signals during action execution and observation | |
| 酵母中单细胞eQTL定位揭示了生长与繁殖之间的权衡 | Boocock, J. | N/A | Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction | |
| 对多巴胺D1和D2受体的药理学调节揭示了非人灵长类动物概率学习中相关的不同神经网络。 | Fujimoto, A. | N/A | Pharmacological modulation of dopamine D1 and D2 receptors reveals distinct neural networks related to probabilistic learning in non-human primates. | |
| 一项针对大脑发育的广泛筛查发现，后扣带回皮质在持久记忆的形成中起着关键作用。 | Jin, B. | N/A | A developmental brain-wide screen identifies retrosplenial cortex as a key player in the emergence of persistent memory | |
| 多种微生物的还原脱卤作用在深海冷泉的生物地球化学循环中起着核心作用。 | Han, Y. | N/A | Reductive dehalogenation by diverse microbes is central to biogeochemical cycles in deep-sea cold seeps | |
| 用于在多光子荧光显微镜中映射原位网络级神经血管耦合的深度学习流程 | Rozak, M. W. | N/A | A Deep Learning Pipeline for Mapping in situ Network-level Neurovascular Coupling in Multi-photon Fluorescence Microscopy | |
| 超灵活神经网络：在紧凑的4神经元电路中快速切换逻辑操作 | White, A. J. | N/A | Hyper-Flexible Neural Networks: Rapidly Switching between Logic Operations in a Compact 4-Neuron Circuit | |
| 缓慢扩散的营养物质的排斥作用增强了趋向移动源的趋化性 | Bloxham, B. | N/A | Repulsion from slow-diffusing nutrients improves chemotaxis towards moving sources | |
| “撕裂袋机制”：通过整体释放的两侧体（amphiectosomes）的限制性膜破裂释放小细胞外囊泡 | Visnovitz, T. | N/A | A "torn bag mechanism" of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes) | |
| 一种基于数据驱动的潜变量方法来验证研究领域标准框架 | Quah, S. K. L. | N/A | A Data-Driven Latent Variable Approach to Validating the Research Domain Criteria Framework | |
| 人道主义背景下无性繁殖作物面临的病原体和害虫风险：为喀麦隆和埃塞俄比亚制定国家植物健康风险分析 | Mouafo-Tchinda, R. | N/A | Pathogen and pest risks to vegetatively propagated crops in humanitarian contexts: Toward a national plant health risk analysis for Cameroon and Ethiopia | |
| 唾液刺激会影响葡萄酒中香气的释放；一项关于微生物群、生物化学和参与者来源的研究 | Ruan, X. | N/A | Stimulation of saliva affects the release of aroma in wine; a study of microbiota, biochemistry and participant origin | |
| 在玉米中进行重复的分化选择实验进化，鉴定出与植物高度相关的SNPs | Tost, M. | N/A | Experimental evolution in maize with replicated divergent selection identifies plant-height associated SNPs | |
| 应用三维相关结构光照明显微镜和X射线断层扫描技术来表征单纯疱疹病毒1型的形态发生过程。 | Nahas, K. L. | N/A | Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis | |
| 灵长类动物丘脑核选择抽象规则并塑造前额叶动力学 | Phillips, J. M. | N/A | Primate thalamic nuclei select abstract rules and shape prefrontal dynamics | |
| 酵母核糖体蛋白mRNA的3'-非翻译区域决定了同源蛋白在核糖体中的整合，并招募了执行特定功能所需的因子。 | Singh, R. | N/A | The 3'-untranslated regions of yeast ribosomal protein mRNAs determine paralog incorporation into ribosomes and recruit factors necessary for specialized functions | |
| 后内侧丘脑在调节纹状体回路和选择行为中的作用 | Yonk, A. J. | N/A | Role of Posterior Medial Thalamus in the Modulation of Striatal Circuitry and Choice Behavior | |
| 内皮钙离子爆发介导了转移性肿瘤细胞的渗出。 | Peralta, M. | N/A | Endothelial calcium firing mediates extravasation of metastatic tumor cells. | |
| 喀麦隆黑蝇（双翅目：蚋科）携带着大量（RNA）病毒。 | De Coninck, L. | N/A | Cameroonian blackflies (Diptera: Simuliidae) harbour a plethora of (RNA) viruses | |
| 多元模型和层次模型的互补优势在识别认知控制中的个体差异方面 | Freund, M. C. | N/A | Complementary benefits of multivariate and hierarchical models for identifying individual differences in cognitive control | |
| 识别认知控制中个体差异的多变量和分层模型的互补优势 | Freund, M. C. | N/A | Complementary benefits of multivariate and hierarchical models for identifying individual differences in cognitive control | |
| 通过抗环孢子蛋白单克隆抗体在肝脏中延迟杀死恶性疟原虫伯氏疟原虫 | Aguirre-Botero, M. C. | N/A | Late killing of Plasmodium berghei in the liver by an anti-circumsporozoite protein monoclonal antibody | |
| 性特异性优势及其对性对抗位点等位基因多样性的影响 | Siljestam, M. | N/A | Sex-Specific Dominance and Its Effects on Allelic Diversity in Sexually Antagonistic Loci | |
| SH3结合基序的邻近残基在体内参与相互作用 | Jordan, D. F. | N/A | Residues Neighboring an SH3-Binding Motif Participate in the Interaction In Vivo | |
| RNA/DNA结合蛋白TDP43调控DNA错配修复基因，对基因组稳定性具有重要意义 | Provasek, V. | N/A | RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability | |
| 解析宿主遗传和因素对年轻群体尿液微生物组的影响 | Zou, L. | N/A | Unraveling the impact of host genetics and factors on the urinary microbiome in a young population | |
| 对13种突变特征归属工具进行基准测试，包括一种新的改进算法 | Jiang, N. | N/A | Benchmarking 13 tools for mutational signature attribution, including a new and improved algorithm | |
| 通过多拷贝质粒上的杂合性实现细菌种群的进化拯救 | Dewan, I. | N/A | Evolutionary rescue of bacterial populations by heterozygosity on multicopy plasmids | |
| Solu - 一个用于实时基因组病原体监测的云平台 | Moilanen, T. J. | N/A | Solu - a Cloud Platform for Real-Time Genomic Pathogen Surveillance | |
| 海马重播的空间定位需要多巴胺信号传递 | Kleinman, M. R. | N/A | Spatial localization of hippocampal replay requires dopamine signaling | |
| HistoGWAS：一种利用人工智能实现组织表型自动化遗传分析的框架 | Chaudhary, S. | N/A | HistoGWAS: An AI-enabled Framework for Automated Genetic Analysis of Tissue Phenotypes in Histology Cohorts | |
| 力监测揭示了在停止信号任务中运动控制的单次试验动力学 | Ramawat, S. | N/A | Force monitoring reveals single trial dynamics of motor control in a stop signal task | |
| 一个共享的威胁预感电路会在不同时刻被确定和不确定的威胁动态地激活。 | Cornwell, B. R. | N/A | A shared threat-anticipation circuit is dynamically engaged at different moments by certain and uncertain threat | |
| 线虫端粒进化中端粒结合蛋白的强健结合能力与偶尔的基因丢失 | Song, H. | N/A | Robust Binding Capability and Occasional Gene Loss of Telomere-Binding Proteins Underlying Telomere Evolution in Nematoda | |
| 大规模计算建模分析H5流感变种对抗HA1中和抗体的效果 | Ford, C. T. | N/A | Large-Scale Computational Modeling of H5 Influenza Variants Against HA1-Neutralizing Antibodies | |
| 靶向IRE1α可改善胰岛素敏感性、促进产热，并抑制肥胖状态下代谢活跃的脂肪组织巨噬细胞 | Wu, D. | N/A | Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in obesity | |
| 高脂饮食相关的蛋白质限制在幼鼠中引起代谢失调，但未导致肥胖 | Joly, A. | N/A | Protein restriction associated with high fat induces metabolic dysregulation without obesity in juvenile mice | |
| 短暂的睡眠中断会改变海马体和皮层中表达生长抑素的中间神经元的突触结构 | Raven, F. | N/A | Brief sleep disruption alters synaptic structures among hippocampal and neocortical somatostatin-expressing interneurons | |
| 非人灵长类物种在生物医学研究中常见的寿命和健康寿命比较 | Huber, H. F. | N/A | Comparative lifespan and healthspan of nonhuman primate species common to biomedical research | |
| 利用扩展拼贴光片显微技术对无性扁形虫的神经元异速生长和神经肌肉投射进行三维重建 | Lu, J. | N/A | 3D Reconstruction of Neuronal Allometry and Neuromuscular Projections in Asexual Planarians Using Expansion Tiling Light Sheet Microscopy | |
| 隐球菌新形隐球菌STRIPAK复合物调控基因组稳定性、性发育和毒力 | Peterson, P. P. | N/A | The Cryptococcus neoformans STRIPAK complex controls genome stability, sexual development, and virulence | |
| 富含褐藻素的海带提取物抑制流感感染 | Mega, D. F. | N/A | Phlorotannin rich Ascophyllum nodosum seaweed extract inhibits influenza infection | |
| 致癌代谢物D-2-羟基戊二酸（D-2-hydroxyglutarate）促进IDH突变型胶质瘤中控制小胶质细胞激活的谱系特异性增强子的DNA高甲基化。 | Laurenge, A. | N/A | The oncometabolite D-2-hydroxyglutarate promotes DNA hypermethylation at lineage-specific enhancers controlling microglial activation in IDHmut gliomas | |
| 利用体内钙成像技术检测关节神经的自发活动，并通过家庭笼分析监测关节炎小鼠模型中活动变化的情况。 | Goodwin, G. L. | N/A | Using in vivo calcium imaging to examine joint neuron spontaneous activity and home cage analysis to monitor activity changes in mouse models of arthritis | |
| 基于活性蛋白质谱分析系统优化，用于在生物治疗药物物质中鉴定低至10 ppb的多聚山梨酯降解酶 | Tsukidate, T. | N/A | Systematic Optimization of Activity-Based Protein Profiling for Identification of Polysorbate-Degradative Enzymes in Biotherapeutic Drug Substance Down to 10 ppb | |
| 先前对自身能力的预期会偏差自我信念的形成，并阻碍后续的修正。 | Schröder, A. | N/A | Prior expectations about own abilities bias self-belief formation and hinder subsequent revision | |
| 在猕猴下丘中视觉诱发活动与听觉反应的可变调制 | Schmehl, M. N. | N/A | Visually-evoked activity and variable modulation of auditory responses in the macaque inferior colliculus | |
| 在斑马鱼神经杆内局部光遗传激活NMYII会导致长距离、不对称的力传导。 | Crellin, H. A. | N/A | Local optogenetic NMYII activation within the zebrafish neural rod results in long-range, asymmetric force propagation | |
| GCK-MODY中独特的持续时间和饮食依赖性脂质谱及肾脏并发症 | Huang, Y. | N/A | Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY | |
| 结构导向设计、合成及表征C22和C32修饰的FK520类似物，其对人致病真菌的活性增强 | Dome, P. A. | N/A | Structure-guided design, synthesis, and characterization of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi | |
| 使用吉布斯振铃衰减的T1w/T2w-FLAIR髓鞘MRI绘制皮层层特定区域边界 | Autio, J. A. | N/A | Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI | |
| 独特的表达谱揭示了三叉神经系统中胶质细胞的参与，这与创伤后头痛有关。 | Nagarajan, G. | N/A | Distinct expression profile reveals glia involvement in the trigeminal system attributing to post-traumatic headache | |
| 海洋杜父鱼成对胸鳍上的表皮微结构提示了新的功能假说，支持其在底栖环境中的固定栖息。 | Kane, E. A. | N/A | Epidermal microstructures on the paired fins of marine sculpins suggest new functional hypotheses supporting benthic station-holding | |
| 使用肌电图进行可泛化的手势识别 | Yun, R. | N/A | Generalizable gesture recognition usingmagnetomyography | |
| 一种用于大鼠在空间条件下自发探索和操作性条件化社会信息的新型行为装置 | Wise, T. B. | N/A | A novel behavioral apparatus for spontaneous exploration and operant conditioning of social information under spatial conditions in rats | |
| 高通量优化基于纸的免细胞生物传感器 | Garcia, D. C. | N/A | High-Throughput Optimization of Paper-Based Cell-Free Biosensors | |
| 多聚腺苷酸酶PAPI在致病菌中对毒力质粒的维持是必需的。 | Schubert, K. | N/A | The polyadenylase PAPI is required for virulence plasmid maintenance in pathogenic bacteria | |
| 窦房结细胞中兰尼碱受体簇网络的结构-功能关系 | Maltsev, A. V. | N/A | Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells | |
| 股二头肌长头的远端激活程度更大，反映了运动单位动作电位性质的近端到远端的差异。 | Albarello, J. C. d. S. | N/A | Greater distal activation of the biceps femoris long head reflects proximodistal differences in motor unit action potential properties. | |
| APOE基因型和生物学年龄影响与生物能量学相关的多组学关联 | Ellis, D. S. | N/A | APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics | |
| 肌球蛋白轻链3作为神经坏死病毒通过巨胞饮途径进入宿主细胞的受体 | Yao, L. | N/A | Myosin light chain 3 serves as a receptor for nervous necrosis virus entry into host cells via the macropinocytosis pathway | |
| 从牛胚胎干细胞生成培养牛肉 | Rui, X. | N/A | Generation of cultured beef from bovine embryonic stem cells | |
| 芳香族氨基酸相互作用强度的交叉：酪氨酸与苯丙氨酸在生物分子凝聚物中的对比 | De Sancho, D. | N/A | Crossover in Aromatic Amino Acid Interaction Strength: Tyrosine vs. Phenylalanine in Biomolecular Condensates | |
| 欧洲人畜共患的蜱传脑炎（TBE）发生概率的时空年度变化建模 | Dagostin, F. | N/A | Modeling spatio-temporal annual changes in the probability of human tick-borne encephalitis (TBE) occurrence across Europe | |
| 脂质分离降低了高曲率囊泡出芽的能垒 | Schachter, I. | N/A | Lipid Demixing Reduces Energy Barriers for High Curvature Vesicle Budding | |
| 用于细胞表面跨膜光学和化学标记的工具 | Innes-Gold, S. | N/A | Tools for intersectional optical and chemical tagging on cell surfaces | |
| 真菌毒素念珠菌素在芯片肠道模型中破坏上皮屏障完整性并引发炎症 | Morelli, M. | N/A | Fungal toxin candidalysin impairs epithelial barrier integrity and initiates inflammation in a gut-on-chip model | |
| 毒力因子念珠菌素在芯片肠道模型中破坏上皮屏障完整性并引发炎症 | Morelli, M. | N/A | Virulence factor candidalysin impairs epithelial barrier integrity and initiates inflammation in a gut-on-chip model | |
| Squeakuences：一种便携式工具，用于格式化干净无瑕的序列，以消除生物信息学软件的不兼容性 | Lane, L. E. | N/A | Squeakuences: a portable tool for formatting squeaky-clean sequences to eliminate bioinformatic software incompatibilities | |
| 揭开睡眠之谜：探索近期在洛基城堡附近发现的古菌门Lokiarchaeota中的系统基因组睡眠信号 | Pandi-Perumal, S. R. | N/A | Unraveling the Mysteries of Sleep: Exploring Phylogenomic Sleep Signals in the Recently Characterized Archaeal Phylum Lokiarchaeota near Loki's Castle | |
| 利用苦艾叶提取物进行生物银纳米粒子的植物辅助合成：表征、抗菌、抗炎及急性毒性特征 | Nyuyfoni, G. F. | N/A | Phytoassisted synthesis of biogenic silver nanoparticles using Vernonia amygdalina leaf extract: characterization, antibacterial, anti-inflammatory, and acute toxicity profile | |
| ABRpresto：一种利用子平均间的重采样互相关进行听觉脑干反应自动阈值设定的算法 | Shaheen, L. A. | N/A | ABRpresto: An algorithm for automatic thresholding of the Auditory Brainstem Response using resampled cross-correlation across subaverages | |
| 通过X射线晶体学鉴定出的电压门控钠通道中对挥发性麻醉剂具有功能重要性的结合位点 | Hollingworth, D. | N/A | Functionally important binding site for a volatile anesthetic in a voltage-gated sodium channel identified by X-ray crystallography | |
| dArc1调控果蝇糖奖励的评价 | Bervoets, S. | N/A | dArc1 controls sugar reward valuation in Drosophila melanogaster | |
| 用勺子处理空间分辨转录组数据中的均值-方差关系 | Shah, K. H. | N/A | Addressing the mean-variance relationship in spatially resolved transcriptomics data with spoon | |
| 通过剪接进化的视角增强转录组注释 | Zang, X. C. | N/A | Augmenting Transcriptome Annotations through the Lens of Splicing Evolution | |
| Rthoptera：R语言中的标准化昆虫生物声学分析 | Rivas, F. | N/A | Rthoptera: standardised insect bioacoustics in R | |
| 基于单个神经元活动的前额叶皮层图谱 | Le Merre, P. | N/A | A Prefrontal Cortex Map based on Single Neuron Activity | |
| 鹦鹉发声学习能力的进化 | Krasheninnikova, A. | N/A | Evolution of vocal production learning in parrots | |
| 通过厌氧光敏化实现产油微藻培养的阿克森化。 | Iyer, A. | N/A | Axenisation of oleaginous microalgal cultures via anoxic photosensitisation. | |
| 抗噬菌体防御中的淀粉样蛋白信号 | Ibarlosa, L. | N/A | Amyloid signaling in antiphage defense | |
| 视蛋白的海洋 | De Vivo, G. | N/A | An ocean of opsins | |
| CosinorTest：一个基于Cosinor模型的转录组应用中的昼夜节律和差异分析R Shiny应用程序 | Ding, H. | N/A | CosinorTest: An R Shiny App for Cosinor-model-based circadian and differential analysis in transcriptomic applications | |
| 在意识障碍的多种恢复过程中，一个统一的中央丘脑机制 | Zhang, H. | N/A | A unified central thalamus mechanism underlying diverse recoveries in disorders of consciousness | |
| 生命周期中噪声环境下的语音感知：蒙古沙鼠与人类的比较研究 | Juchter, C. | N/A | Speech-in-noise perception across the lifespan: A comparative study in Mongolian gerbils and humans | |
| 利用RESA作为代表性标记蛋白，通过超微结构扩展显微镜（U-ExM）对疟原虫致密颗粒进行可视化研究 | Fukumoto, J. | N/A | Ultrastructural expansion microscopy (U-ExM) visualization of malaria parasite dense granules using RESA as a representative marker protein | |
| 对两种稀有鲸类物种解剖学的贡献：虎鲸（Lagenorhynchus cruciger）和眼镜海豚（Phocoena dioptrica） | Graic, J.-M. | N/A | A CONTRIBUTION TO THE ANATOMY OF TWO RARE CETACEAN SPECIES: THE HOURGLASS DOLPHIN (Lagenorhynchus cruciger) AND THE SPECTACLED PORPOISE (Phocoena dioptrica) | |
| 对紫杉树进行多重扰动揭示了能够实现巴卡亭III和紫杉醇前体全生物合成的隐秘蛋白质 | McClune, C. J. | N/A | Multiplexed perturbation of yew reveals cryptic proteins that enable a total biosynthesis of baccatin III and Taxol precursors | |
| 基于算法的研究揭示了蛋白质腔内水在不同距离壁面处的差异动力学 | Francis, A. X. | N/A | An algorithm-based investigation reveals the differential dynamics of water inside protein cavity as a function of distance from its wall | |
| 建模溶瘤痘苗病毒疗法突显了中性粒细胞对肿瘤抑制的影响 | Satani, S. | N/A | Modeling Oncolytic Vaccinia Virus Therapy Highlights Neutrophil Impact on Tumor Suppression | |
| 希望他人：匹兹堡大学乳腺癌快速尸检计划的研究成果 | Chang, A. C. | N/A | Hope for Others: Research Results from the University of Pittsburgh Rapid Autopsy Program for Breast Cancer | |
| 脑功能连接作为血液学指标与儿童β地中海贫血主要型认知衰退之间的中介因素 | Xu, S. | N/A | Brain functional connectivity as a mediator between hematological metrics and cognitive decline in children with beta-thalassemia major | |
| 抑郁和焦虑障碍中基底前脑对内在脑网络的调控改变 | Jamieson, A. J. | N/A | Altered basal forebrain regulation of intrinsic brain networks in depressive and anxiety disorders | |
| 与侵染华山松的树皮甲虫相关的长喙壳菌，并描述了来自中国西部的七个新种 | Chen, M. | N/A | Ophiostomatoid fungi associated with bark beetles infesting Pinus armandii, with characterizations of seven new species from western China | |
| 与感染马尾松的黄毛脊虎天牛相关的长喙壳菌，包括在中国新描述的青原真菌新种的特征 | Liu, K. | N/A | Ophiostomatalean fungi associated with Cyrtogenius luteus infested Pinus massoniana, including characterization of Masuyamyces qingyuanensis sp. nov. in China | |
| 次氯酸在感染中的应用：科学文献的文献计量分析 | Ates, F. M. | N/A | Use of Hypochlorous Acid in Infections: Bibliometric Analysis of Scientific Literature | |
| 通过丝状纳米团簇的蛋白质-RNA凝聚动力学 | Peralta Martinez, R. | N/A | Protein-RNA condensation kinetics via filamentous nanoclusters | |
| TRPV4过度激活增强了细胞收缩力，并在TGFβ2过表达的眼中驱动眼压升高。 | Rudzitis, C. N. | N/A | TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes | |
| 通过泛基因组学鉴定和表征古菌假胞壁酸生物合成基因 | Lupo, V. | N/A | Identification and Characterization of Archaeal Pseudomurein Biosynthesis Genes through Pangenomics | |
| 拟南芥中着丝粒和纺锤体组装检查点的功能框架 | Pettko-Szandtner, A. | N/A | Functional framework of the kinetochore and spindle assembly checkpoint in Arabidopsis thaliana | |
| 邻近蛋白质组学为探索Afadin功能及细胞间粘附连接的复杂性提供了新的资源。 | Choi, W. | N/A | Proximity proteomics provides a new resource for exploring the function of Afadin and the complexity of cell-cell adherens junctions | |
| 中心体蛋白-Sfi1的渔网状网格驱动巨型细胞Spirostomum ambiguum的超快钙激活收缩 | Lannan, J. | N/A | Fishnet mesh of centrin-Sfi1 drives ultrafast calcium-activated contraction of the giant cell Spirostomum ambiguum | |
| 中心粒-Sfi1的渔网状网格驱动巨型细胞Spirostomum ambiguum的超快钙激活收缩 | Lannan, J. | N/A | Fishnet mesh of centrin-Sfi1 drives ultrafast calcium-activated contraction of the giant cell Spirostomum ambiguum | |
| 跨膜耦合加速液态蛋白质凝聚物的生长 | Lee, Y. | N/A | Transmembrane coupling accelerates the growth of liquid-like protein condensates | |
| 昼夜节律钟调控对植食性动物相关分子模式的受体介导免疫反应 | Palacios, N. G. | N/A | The circadian clock regulates receptor-mediated immune responses to an herbivore-associated molecular pattern | |
| 在玉米的热胁迫过程中，自噬、未折叠蛋白反应与细胞质热胁迫反应之间的相互作用 | Tang, J. | N/A | Interplay between autophagy, the unfolded protein response and the cytoplasmic heat stress response during heat stress in maize | |
| 天然细菌素作为潜在药物候选，靶向奶牛乳腺炎病原体的核心蛋白质 | Hasnat, S. | N/A | Natural Bacteriocins as Potential Drug Candidates Targeting Core Proteins in Mastitis Pathogens of Dairy Cattle | |
| P4HA1基因敲除小鼠乳腺基因调控网络的单细胞分析 | Gupta, A. | N/A | Single-Cell Analysis of Gene Regulatory Networks in the Mammary Glands of P4HA1-knockout mice | |
| 研究内源性大麻素诱导的短杆菌肽电流变化 | Mayar, S. | N/A | Examining Changes in Gramicidin Current Induced by Endocannabinoids | |
| 奈拉替尼，一种用于治疗乳腺癌的临床药物，通过抑制ASK1来预防动脉粥样硬化。 | Zhang, F. | N/A | Neratinib, a clinical drug against breast cancer, protects against atherosclerosis via ASK1 inhibition | |
| 从空中无人机到数量性状位点（QTL）：利用新一代表型分析揭示田间种植的莴苣（Lactuca sativa）中颜色和高度的遗传机制 | Dijkhuizen, R. F. | N/A | From aerial drone to QTL: Leveraging next-generation phenotyping to reveal the genetics of color and height in field-grown Lactuca sativa | |
| 父本来源的基因组通过母本植物抑制拟南芥种子的休眠诱导 | Barros-Galvao, T. | N/A | The paternally derived genome opposes seed dormancy induction by the mother plant in Arabidopsis | |
| 高效多用途的油菜转化技术助力新育种技术的发展 | Ille, K. | N/A | Efficient and Versatile Rapeseed Transformation for New Breeding Technologies | |
| 从数量性状位点到机制：连锁整合假设检验（LIgHT）揭示了遗传调控的应激耐受机制 | Hoh, D. | N/A | From Quantitative Trait Loci towards Mechanisms: Linkage Integration Hypothesis Testing (LIgHT) Sheds Light on the Mechanisms of Genetically Modulated Stress Tolerance | |
| OsMORF蛋白特异性地促进双定位RNA编辑因子OsPGL1与其目标RNA的结合 | Xiao, H. | N/A | OsMORF protein selectively promotes the dual-localized RNA editing factor OsPGL1 binding to its target RNA | |
| 茉莉酸通过嘌呤受体P2K1介导植物对外源性ATP的响应 | Jewell, J. B. | N/A | Jasmonate Primes Plant Responses to Extracellular ATP through Purinoceptor P2K1 | |
| 双NBT方法：利用MdAGG防御凝集素通过基因编辑和内生化促进苹果抗火疫病。 | Bodelot, A. | N/A | Dual NBT Approach: Gene Editing and Intragenesis to promote Fire Blight Resistance in Apple using MdAGG defense lectins. | |
| 一种富含藻类营养、优化的培养基，适用于快速生长和高甘油三酯积累 | Jeffers, T. L. | N/A | An algal nutrient-replete, optimized medium for fast growth and high triacylglycerol accumulation | |
| 时间和温度解析的拟南芥剪接相关突变体的转录组分析 | Nardeli, S. M. | N/A | Time and temperature-resolved transcriptomic analysis of Arabidopsis splicing-related mutants | |
| CCR2介导的单核细胞招募对放射治疗引起的肠道毒性具有保护作用 | Pun, N. | N/A | CCR2-driven monocyte recruitment is protective against radiotherapy-induced intestinal toxicity | |
| 丛枝菌根真菌基因型及其核组织作为宿主植物营养获取和稳定碳捕获的驱动因素 | Ferguson, R. | N/A | Arbuscular mycorrhizal fungal genotype and nuclear organization as driving factors in host plant nutrient acquisition and stable carbon capture | |
| 防御性共生体以低成本为宿主提供高水平的自然敌害防护：一项元分析 | Cesar, C. S. | N/A | Defensive symbionts provide high protection against natural enemies at low cost to hosts: a meta-analysis | |
| 凝聚素II复合物在红细胞生成过程中调控必需基因表达程序的表达 | Abid, D. | N/A | The Condensin II Complex Regulates the Expression of Essential Gene Expression Programs During Erythropoiesis | |
| 多组学潜在变量数据整合揭示了乌干达结核菌素皮肤试验（TST）/干扰素伽马释放试验（IGRA）转化抗性相关的多细胞结构途径 | Cox, M. S. | N/A | Multi-omic latent variable data integration reveals multicellular structure pathways associated with resistance to tuberculin skin test (TST)/interferon gamma release assay (IGRA) conversion in Uganda | |
| 机器学习揭示了胶质母细胞瘤和骨肉瘤的新靶点 | Li, N. | N/A | Machine learning reveals novel targets for both glioblastoma and osteosarcoma | |
| 使用时空图卷积网络对大脑fMRI数据进行肠易激综合征分类 | Wu, J. | N/A | Classifying Irritable Bowel Syndrome Using Spatio-Temporal Graph Convolution Networks on Brain fMRI Data | |
| DrugProtAI：探索性靶蛋白未来研究指南 | Halder, A. | N/A | DrugProtAI: A guide to the future research of investigational target proteins | |
| NovumRNA：从RNA测序数据中准确预测非经典肿瘤抗原 | Ausserhofer, M. | N/A | NovumRNA: accurate prediction of non-canonical tumor antigens from RNA sequencing data | |
| PDBe工具，用于对蛋白质数据库中的小分子进行深入分析 | Choudhary, P. | N/A | PDBe tools for an in-depth analysis of small molecules in the Protein Data Bank | |
| 棒的棒：淀粉样蛋白肽-DNA复合物的结构特征 | Arzamastsev, G. | N/A | Stick of Sticks: Structural Features of the Amyloidogenic Peptide-DNA Complex | |
| 细胞-基质机械反馈中的关键间距控制组织凝集 | Peng, X. | N/A | Critical Spacing in Cell-Matrix Mechanical Feedback Controls Tissue Condensation | |
| 空间多组学在胶质母细胞瘤切除边缘定义了一个共同的浸润特征 | Pai, B. | N/A | Spatial multi-omics defines a shared infiltrative signature in glioblastoma at the resection margin | |
| 一种SH3结合的变构调节剂稳定了与AML相关的Src家族激酶Hck的全局构象 | Selzer, A. M. | N/A | An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck | |
| SysQuan：将SILAC小鼠用于人类蛋白质组经济实惠的绝对定量 | Mohammed, Y. | N/A | SysQuan: repurposing SILAC mice for the affordable absolute quantitation of the human proteome | |
| 通过选择性光遗传激活海马切片中的门牙细胞，研究齿状回颗粒细胞的场EPSP。 | Bernstein, H. L. | N/A | Field EPSPs of dentate gyrus granule cells studied by selective optogenetic activation of hilar mossy cells in hippocampal slices. | |
| 探究习惯性睡眠质量对情景记忆表现的影响：基于脑电图的表征相似性分析 | Seraji, M. | N/A | Investigating the Impact of Habitual Sleep Quality on Episodic Memory Performance: An EEG-Based Representational Similarity Analysis | |
| 整合的高维分析揭示了CD4 T细胞表位特异性和表型在应对结核分枝杆菌反应中的出乎意料的多样性 | Mead, H. L. | N/A | Integrated, high-dimensional analysis of CD4 T cell epitope specificities and phenotypes reveals unexpected diversity in the response to Mycobacterium tuberculosis | |
| 淡水SAR11（LD12）中的聚羟基丁酸酯生产 | Bennett, B. D. | N/A | Polyhydroxybutyrate production in freshwater SAR11 (LD12) | |
| p53的参与是哺乳动物细胞核中未折叠蛋白反应的标志。 | Park, J. H. | N/A | p53 engagement is a hallmark of an unfolded protein response in the nucleus of mammalian cells | |
| 通过二次抽样：推断生物多样性随时间和跨研究者的变化 | Elahi, R. | N/A | Passing the quadrat: inferring biodiversity change over time and across investigators | |
| 气候变化对草本旋花科植物在塞拉多和大西洋森林生物群落（巴西东南部）的影响：高温是否成为杂草的威胁？ | Barbosa, J. C. J. | N/A | Too hot for the weeds? Exploring the impact of climate change in herbaceous Convolvulaceae in Cerrado and Mata Atlantica biomes (SE Brazil) | |
| 体型大小和栖息地破碎化如何影响蜥蜴的灭绝？一项关于巴西塞拉多地区人工岛屿的长期案例研究 | Miranda, R. B. | N/A | How do body size and habitat fragmentation influence extinction in lizards? A long-term case study on artificial islands in the Brazilian Cerrado | |
| 松鱼（Lagodon rhomboides）具有广泛的温度耐受性和高度的线粒体基因连通性。 | Eaton, K. M. | N/A | Broad thermal tolerance and high mitochondrial genetic connectivity in the pinfish (Lagodon rhomboides) | |
| 重复扩增的并行深度分析：适用于纳米孔R10流式细胞仪的更新版Clin-CATS工作流程 | Scholz, V. | N/A | Parallel in-depth analysis of repeat expansions: an updated Clin-CATS workflow for nanopore R10 flow cells | |
| 利用特征选择算法表征石珊瑚组织丧失病中不同组织状态的基因表达谱 | Beavers, K. M. | N/A | Characterizing gene expression profiles of various tissue states in stony coral tissue loss disease using a feature selection algorithm | |
| 优化聚合物纳米颗粒上Angiopep-2的密度以增强血脑屏障穿透和胶质母细胞瘤靶向：来自体外和体内实验的见解 | Zhang, W. | N/A | Optimizing Angiopep-2 Density on Polymeric Nanoparticles for Enhanced Blood-Brain Barrier Penetration and Glioblastoma Targeting: Insights from In Vitro and In Vivo Experiments | |
| 体内工程化四价CAR巨噬细胞通过抗原扩散突破肿瘤屏障，重塑肿瘤微环境，并克服肿瘤异质性。 | Zhang, S. | N/A | In vivo engineered quadrivalent CAR-macrophages break tumor barrier,remodel TME and overcome tumor heterogeneity through antigen spreading | |
| 长读多重多样单体型重建 | Shaw, J. | N/A | devider: long-read reconstruction of many diverse haplotypes | |
| 扩展和改进的全鼠脑CCFv3注释和尼氏图谱 | Piluso, S. | N/A | An extended and improved CCFv3 annotation and Nissl atlas of the entire mouse brain | |
| 使用可解释深度学习预测特定上下文调控程序和通路 | Doncevic, D. | N/A | Prediction of context-specific regulatory programs and pathways using interpretable deep learning | |
| 绘制甲状腺肿瘤的分子图谱：对源于滤泡的肿瘤进行全面的蛋白质组学和磷酸蛋白质组学分析 | Bossart, J. | N/A | Mapping the Molecular Landscape of Thyroid Neoplasms: A Comprehensive Proteomic and Phosphoproteomic Analysis Across Tumors of Follicular Origin | |
| 可解释的PROTAC降解预测：基于结构信息的深度三元注意力框架 | Chen, Z. | N/A | Interpretable PROTAC degradation prediction with structure-informed deep ternary attention framework | |
| 一种精确且快速的SAT公式化方法用于DCJ距离计算 | Sarnaik, A. M. | N/A | An Exact and Fast SAT Formulation for the DCJ Distance | |
| 揭示核小体动态：利用全原子与粗粒化模拟并结合主成分分析的比较研究 | MOULICK, A. G. | N/A | Unveiling Nucleosome Dynamics: A Comparative Study Using All-Atom and Coarse-Grained Simulations Enhanced by Principal Component Analysis | |
| 工程化的乙酰化模式在体外驱动大规模染色质组织 | Fukai, Y. | N/A | Engineered acetylation patterns drive large-scale chromatin organization in vitro | |
| 粘性酶：通过底物依赖的酶聚集提高代谢效率 | Martinez-Calvo, A. | N/A | Sticky enzymes: increased metabolic efficiency via substrate-dependent enzyme clustering | |
| 一种多模态深度学习框架，结合了序列和结构信息，用于肿瘤抗原预测 | Jin, R. | N/A | A Multi-Modal Deep Learning Framework with Both Sequence and Structure for Tumor Antigens Prediction | |
| 表观遗传学中的分数阶微积分 | Nasrolahpour, H. | N/A | Fractional Calculus in Epigenetics | |
| 耐力运动通过儿童期和成年期提高血浆成熟脑源性神经营养因子水平，成年期的效果更为显著。 | Edman, S. | N/A | Endurance Exercise Elevates Plasma Mature Brain-Derived Neurotrophic Factor through Child- and Adulthood, with Amplified Effects in Adults | |
| RTF1通过H2B单泛素化介导Th17细胞分化的表观遗传调控 | Galan, C. | N/A | RTF1 mediates epigenetic control of Th17 cell differentiation via H2B monoubiquitination | |
| 释放引进的寄生虫不会影响它们的建立或成功。 | Kishinevsky, M. | N/A | Enemy release of introduced parasitoids does not affect their establishment or success | |
| 全基因组测序跨越时间和空间揭示了佛罗里达灌丛鸦种群数量下降和基因流动减少的影响。 | Nguyen, T. N. | N/A | Whole-genome sequencing across space and time reveals impact of population decline and reduced gene flow in Florida Scrub-Jays | |
| JOnTADS：Hi-C数据中TADs和条纹的统一调用器 | Zeng, Q. | N/A | JOnTADS: a unified caller for TADs and stripes in Hi-C data | |
| 基于人工智能增强的物理学对接用于抗体-抗原复合物预测 | Gaudreault, F. | N/A | AI-Augmented Physics-Based Docking for Antibody-Antigen Complex Prediction | |
| 分子模拟与个性化医疗的结合：ClC-5反向转运体的机制及其与Dent病的起源 | Macaluso, V. | N/A | Molecular Simulations Meet Personalized Medicine. The Mechanism of Action of ClC-5 Antiporter and the Origin of Dent's Disease | |
| 在模拟无序蛋白质的过程中，将折叠过程与能量陷阱分离开来 | Lotthammer, J. M. | N/A | Disentangling folding from energetic traps in simulations of disordered proteins | |
| 泪腺通过细胞旁途径分泌泪液的过程受到肌球蛋白介导的紧密连接通透性调节的调控。 | Ohno, Y. | N/A | Tear secretion via a paracellular pathway in lacrimal gland is regulated by myosin-mediated modulation of tight junction permeability | |
| 颗粒形成型Ca. Accumulibacter富集物分泌组学的元蛋白质组学分析 | van Olst, B. | N/A | Metaproteomic profiling of the secretome of a granule-forming Ca. Accumulibacter enrichment | |
| 多维社会关系塑造了猴子的社会注意力 | Liu, S. | N/A | Multi-dimensional social relationships shape social attention in monkeys | |
| 行为和神经证据表明，在社交互动中存在感知预测 | Lu, J. | N/A | Behavioral and neural evidence for perceptual predictions in social interactions | |
| 在视紫红质P23H大鼠模型中，通过利血平实现性别的光感受器退行性变减弱，该模型用于研究常染色体显性遗传性视网膜色素变性 | Song, H. B. | N/A | Sex-specific attenuation of photoreceptor degeneration by reserpine in a rhodopsin P23H rat model of autosomal dominant retinitis pigmentosa | |
| ENaC参与了囊性纤维化中巨噬细胞功能障碍的发生 | Moran, J. | N/A | ENaC contributes to macrophage dysfunction in cystic fibrosis | |
| 爱泼斯坦-巴尔病毒潜伏膜蛋白1通过劫持IMPDH通路驱动B细胞癌代谢 | Burton, E. | N/A | Epstein-Barr Virus Latent Membrane Protein 1 Subverts IMPDH pathways to drive B-cell oncometabolism | |
| 生物毒素BMAA促进神经母细胞瘤细胞的间充质转化 | Moore, E. | N/A | The biotoxin BMAA promotes mesenchymal transition in neuroblastoma cells | |
| LUMIC：用于细胞多重成像的潜在扩散模型 | Hung, A. Z. | N/A | LUMIC: Latent diffUsion for Multiplexed Images of Cells | |
| 肌营养不良蛋白与Msp300相互作用，调控肌核定位与微管组织 | Padilla, J. R. | N/A | Dystrophin interacts with Msp300 to Regulate Myonuclear Positioning and Microtubule Organization | |
| 绿化速率对方法论和生物学敏感；评论：卫星观测到的南极半岛持续绿化现象 | Bokhorst, S. | N/A | Greening rates are sensitive to methodology and biology; comment to Sustained greening of the Antarctic Peninsula observed from satellites | |
| 自由生活鸣禽的表观遗传潜能与扩散倾向：一种时空方法 | Jimeno, B. | N/A | Epigenetic potential and dispersal propensity in a free-living songbird: a spatial and temporal approach | |
| 栖息地数量和碎片化本身对格兰特维尔小灰蝶遗传多样性的相对影响 | Fernandez Multigner, L. | N/A | Relative Effects of Habitat Amount and Fragmentation Per Se on the Genetic Diversity of The Glanville Fritillary Butterfly | |
| 从二进制数据中识别简约的积累路径和趋同进化 | Giannakis, K. | N/A | Identifying parsimonious pathways of accumulation and convergent evolution from binary data | |
| 反向共敏性可恢复抗生素敏感性 | Chowdhury, F. R. | N/A | Backward collateral sensitivity can restore antibiotic susceptibility | |
| SelNeTime：一个从基因组时间序列数据推断有效种群大小和选择强度的Python包 | Uhl, M. | N/A | SelNeTime: a python package inferring effective population size and selection intensity from genomic time series data | |
| 通过Voronoi方法在空间转录组学中进行综合细胞分箱分割 | Lin, M. | N/A | Integrative cell bin segmentation on spatial transcriptomics by Voronoi | |
| 无虹膜症患者血浆中PAX6半合子不足引起的代谢和神经活性失衡 | Cunha, D. L. | N/A | Metabolic and neuroactivity imbalances in plasma from aniridia patients with PAX6 haploinsufficiency | |
| 进化引导的转录因子设计程序可产生新型T细胞状态 | Takacsi-Nagy, O. | N/A | Evolutionarily guided transcription factor design programs novel T cell states | |
| GCfix：一种快速且精确的片段长度特异性方法，用于校正无细胞DNA中的GC偏倚 | Rafeed, C. | N/A | GCfix: A Fast and Accurate Fragment Length-SpecificMethod for Correcting GC Bias in Cell-Free DNA | |
| 基于图像的低嵌合体体细胞移动元件插入检测的DNA测序编码 | Tan, M. | N/A | Image-based DNA Sequencing Encoding for Detecting Low-Mosaicism Somatic Mobile Element Insertions | |
| 蓝宝石雀鲷（Chrysiptera cyanea）的基因组：支持进一步研究雀鲷科进化的新资源 | Gairin, E. | N/A | The genome of the sapphire damselfish Chrysiptera cyanea: a new resource to support further investigation of the evolution of Pomacentrids | |
| 多功能体外生命支持（ECLS）系统用于肺和肾脏支持的开发：Pneuma-K ECLS系统 | Kwon, J. | N/A | Development of a Multifunctional Extracorporeal Life Support (ECLS) System for Lung and Kidney Support: The Pneuma-K ECLS System | |
| 对羟基苯甲酸酯对子宫胶原蛋白的影响：利用二次谐波产生显微镜、纳米压痕和原子力显微镜的综合与靶向相关性方法 | Arshee, M. R. | N/A | Impact of Paraben on Uterine Collagen: An Integrated and Targeted Correlative Approach Using Second Harmonic Generation Microscopy, Nanoindentation, and Atomic Force Microscopy | |
| 利用微米级tPA珠粒实现高纤溶酶通量和加速纤维蛋白溶解 | Osmond, M. J. | N/A | Harnessing micrometer-scale tPA beads for high plasmin flux and accelerated fibrinolysis | |
| scHiCcompare: 一个用于单细胞Hi-C数据差异分析的R包 | Nguyen, M. | N/A | scHiCcompare: an R package for differential analysis of single-cell Hi-C data | |
| BaNDyT：分子动力学轨迹的贝叶斯网络建模 | Mukhaleva, E. | N/A | BaNDyT: Bayesian Network modeling of molecular Dynamics Trajectories | |
| 人类免疫系统的单细胞图谱揭示了免疫衰老的性别特异性动态 | Rios, M. S. | N/A | Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence | |
| 缓步动物Dsup：与DNA的相互作用及对细胞氧化应激的保护作用 | Ni, G. S. | N/A | Tardigrade Dsup: Interactions with DNA and protection of cells from oxidative stress | |
| 去噪揭示蛋白质晶体中的低占有率群体 | Fadini, A. | N/A | Denoising Reveals Low-Occupancy Populations in Protein Crystals | |
| 阐明UBA7-UBE2L6二硫键复合物形成的机制 | Chen, P.-T. | N/A | Elucidating the Mechanism Underlying UBA7-UBE2L6 Disulfide Complex Formation | |
| 铜在癌细胞中诱导p53的展开，导致癌细胞的侵袭性和化学耐药性。 | Muller, P. A. J. | N/A | Copper induces p53 unfolding in cancer cells, resulting in invasion and chemoresistance | |
| YY1通过与前列腺癌微环境中巨噬细胞内的NUSAP1相互作用，增强了HIF-1α蛋白的稳定性。 | Li, W. | N/A | YY1 Enhances the Stability of HIF-1α Protein by Interacting with NUSAP1 in Macrophages within the Prostate Cancer Microenvironment | |
| 乌特罗司德B，一种被美国FDA指定用于治疗肝细胞癌（HCC）的孤儿药，能够抑制非酒精性脂肪性肝炎（NASH）及其诱发的肝细胞癌。 | Rayginia, T. P. | N/A | Uttroside B, a US-FDA-Designated Orphan Drug Against Hepatocellular Carcinoma (HCC), Impedes Non-alcoholic Steatohepatitis (NASH) and NASH -Induced HCC | |
| 拓扑异构酶IIb结合是癌症基因组中频繁突变元素的基础 | Uusküla-Reimand, L. | N/A | Topoisomerase IIb binding underlies frequently mutated elements in cancer genomes | |
| 人脂肪来源的间充质基质细胞改善了肠皮瘘疾病小鼠模型中的伤口愈合 | Marsiano, N. | N/A | Human adipose-derived mesenchymal stromal cells improved wound healing in enterocutaneous fistulizing disease mouse model | |
| 扭矩与功率在速度之间的权衡：一项关于等速和多平面任务中肩部表现的 | Lee, K. D. L. | N/A | The Trade-Off Between Torque and Power with Speed: A Study of Shoulder Performance During an Isokinetic and Multiplanar Task | |
| 解锁基因库的力量：碱基生长温度的多样性为气候智能型农业提供了机遇 | Gambart, C. | N/A | Unlocking the power of gene banks: diversity in base growth temperature provides opportunities for climate-smart agriculture | |
| 补充维生素D的肥胖小鼠的胰腺变化 | da Rocha, G. | N/A | Pancreatic changes in obese mice supplemented with vitamin D | |
| TREK K2P通道的热敏感性受PKA开关控制，并依赖于微管网络。 | Cordeiro, S. | N/A | Thermosensitivity of TREK K2P channels is controlled by a PKA switch and depends on the microtubular network | |
| 子宫内膜蜕膜反应的停滞决定了流产风险的复发风险 | Muter, J. | N/A | Stalling of the endometrial decidual reaction determines the recurrence risk of miscarriage risk | |
| 加拿大科学研究生的津贴低于贫困线。 | Fraass, A. J. | N/A | Canadian science graduate stipends lie below the poverty line | |
| 加拿大科学研究生的津贴低于贫困线。 | Fraass, A. J. | N/A | Canadian science graduate stipends lie below the poverty line | |
| 单细胞转录组数据中骨骼肌再生细胞群体动力学的微分方程建模 | Al-Ghazawi, R. | N/A | Differential Equation Modeling of Cell Population Dynamics in Skeletal Muscle Regeneration from Single-Cell Transcriptomic Data | |
| 人类阿尔茨海默病脑组织中批量RNAseq研究的系统综述与荟萃分析 | Heberle, B. A. | N/A | Systematic review and meta-analysis of bulk RNAseq studies in human Alzheimer's disease brain tissue | |
| 人类NMNAT2的转录调控：来自三维基因组测序和生物信息学的见解 | Chang, Y. C. | N/A | Transcriptional Regulation of human NMNAT2: Insights from 3D Genome Sequencing and Bioinformatics | |
| 通过实时面部处理对首发精神病的深度多模态表征与分类 | Singh, R. | N/A | Deep Multimodal Representations and Classification of First-Episode Psychosis via Live Face Processing | |
| 解码有向句法结构构建的神经动力学 | Zhao, J. | N/A | Decoding the Neural Dynamics of Headed Syntactic Structure Building | |
| 一种针对NIMA相关激酶7（NEK7）的脑素（CRBN）分子胶降解剂揭示了其在NLRP3炎症小体激活中的情境依赖性作用 | Sylvain, A. | N/A | A cereblon (CRBN) molecular glue degrader of NIMA-related kinase 7 (NEK7) reveals a context-dependent role in NLRP3 inflammasome activation | |
| 莱姆病螺旋体伯氏疏螺旋体（Borreliella burgdorferi）的外表面蛋白C（OspC）顶端的一个特定类型的B细胞表位 | Vance, D. | N/A | A type-specific B cell epitope at the apex of Outer surface protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi | |
| 我们是否在血清学上为禽流感大流行做好了准备？季节性流感疫苗能否帮助我们？ | Sanz-Munoz, I. | N/A | Are we serologically prepared against an avian influenza pandemic and could seasonal flu vaccines help us? | |
| 一种用于金黄色葡萄球菌毒力因子共价靶向的mRNA展示方法 | Wang, S. | N/A | An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor | |
| 一种用于金黄色葡萄球菌毒力因子共价靶向的mRNA展示方法 | Wang, S. | N/A | An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor | |
| GCTransNet：基于全局上下文视觉变换器的3D线粒体实例分割 | Chen, C. | N/A | GCTransNet: 3D mitochondrial instance segmentation based on Global Context Vision Transformers | |
| 探索肥胖青少年在接受减重手术后代谢改善中的器官特异性细胞外囊泡 | Kim, A. | N/A | Exploring Organ-Specific Extracellular Vesicles in Metabolic Improvements Following Bariatric Surgery in Adolescents with Obesity | |
| 索诺兰沙漠异地保护差距分析：绘制保护之路 | Hernandez, M. G. C. | N/A | Sonoran Desert ex situ conservation gap analysis: charting the path towards conservation | |
| 希腊中部尖音库蚊成蚊的越冬 | Ioannou, C. | N/A | Winter Survival of Culex pipiens f. pipiens Adults in Central Greece | |
| 一种应用于物种分布模式机制模型的顺序采样新算法 | Kristensen, N. P. | N/A | A novel sequential sampling algorithm for the application of mechanistic models to species occurrence patterns | |
| 埃塞俄比亚东部哈拉马亚大学辣椒（Capsicum annuum.L）地方品种的遗传变异性分析。 | Sufiyan, A. | N/A | Genetic Variability Analysis of Hot Pepper (Capsicum annuum.L) Landraces at Haramaya University, Eastern Ethiopia. | |
| 人类异种代谢蛋白在肠道微生物群中具有全长和分裂的同源物 | Rendina, M. | N/A | Human xenobiotic metabolism proteins have full-length and split homologs in the gut microbiome | |
| S1P与硫酸肝素衍生物联合治疗以恢复内皮糖萼并对抗促动脉粥样硬化内皮功能障碍 | Mitra, R. | N/A | Co-Therapy with S1P and Heparan Sulfate Derivatives to Restore Endothelial Glycocalyx and Combat Pro-Atherosclerotic Endothelial Dysfunction | |
| 细胞类型特异性表观遗传流行病学研究设计与分析指南。 | Walker, E. M. | N/A | Guidance for the design and analysis of cell-type specific epigenetic epidemiology studies. | |
| T细胞受体-表位预测器的基准测试与ePytope-TCR | Drost, F. | N/A | Benchmarking of T-Cell Receptor - Epitope Predictors with ePytope-TCR | |
| 单细胞组学的无监督深度解耦表示 | Moinfar, A. A. | N/A | Unsupervised Deep Disentangled Representation of Single-Cell Omics | |
| sCellST：一种基于多实例学习的方法，用于利用空间转录组学从H&E图像预测单细胞基因表达 | Chadoutaud, L. | N/A | sCellST: a Multiple Instance Learning approach to predict single-cell gene expression from H&E images using spatial transcriptomics | |
| RNA异构体：在Python中快速渲染RNA异构体结构与表达的交互式可视化 | Heberle, B. A. | N/A | RNApysoforms: Fast rendering interactive visualization of RNA isoform structure and expression in Python | |
| TomoScore：一种用于细胞冷冻电镜质量评估的神经网络方法 | Tan, X. | N/A | TomoScore: A Neural Network Approach for Quality Assessment of Cellular cryo-ET | |
| 一种环境响应型SCLA型GRAS蛋白调控了地钱（Marchantia polymorpha）的生殖策略 | Hoey, D. J. | N/A | An environment-responsive SCLA-type GRAS protein controls reproductive strategy in Marchantia polymorpha | |
| RNA甲基化在红细胞生成过程中调控应激颗粒的形成与功能 | GUNAGE, R. D. | N/A | RNA methylation controls stress granule formation and function during erythropoiesis | |
| 丛枝菌根真菌对长期缺乏和N、P、K不平衡的强烈家庭和公会特异性响应 | Jenab, K. | N/A | Strong family- and guild-specific responses of arbuscular mycorrhizal fungi to long-term deficiencies and imbalances of N, P and K | |
| 活酵母及其代谢产物对熊蜂微群落发育的影响 | Rutkowski, D. | N/A | Effects of live yeasts and their metabolic products on bumble bee microcolony development | |
| 糖原吞噬是一种古老的两侧对称动物途径，通过STBD1结构进化支持代谢适应。 | Ren, L. | N/A | Glycophagy is an ancient bilaterian pathway supporting metabolic adaptation through STBD1 structural evolution | |
| 研究交配系统对秀丽隐杆线虫抗药性进化的影响 | Trubenova, B. | N/A | Investigating the consequences of the mating system for drug resistance evolution in C. elegans | |
| IL-10通过表观遗传机制靶向IRFs以抑制IFN和炎症反应基因 | Mishra, B. | N/A | IL-10 Targets IRFs to Suppress IFN and Inflammatory Response Genes by Epigenetic Mechanisms | |
| 系统筛选增强环状RNA翻译的RNA结合蛋白 | Lu, Q. | N/A | Systematic screen of RNA binding proteins that enhance circular RNA translation | |
| 动物种群的随机子样本可以揭示社会性的内在差异，这对生态学、保护和疾病传播具有重要意义。 | Conteddu, K. | N/A | Random subsamples of animal populations can reveal intrinsic differences in sociality with key implications in ecology, conservation and disease transmission | |
| 可解释且稳健的机器学习用于探索和分类声景数据 | Omprakash, A. | N/A | Interpretable and Robust Machine Learning for Exploring and Classifying Soundscape Data | |
| 更好的抗体互补决定区设计先验分布 | Wu, J. | N/A | Better Prior Distribution for Antibody Complementarity-Determining Regions Design | |
| 脂质诱导的α-突触核蛋白聚集的全局动力学模型及其通过小分子抑制的研究 | Stevenson, A. | N/A | Global kinetic model of lipid-induced alpha-synuclein aggregation and its inhibition by small molecules | |
| DeFrND：使用设计膜支架肽的无洗涤剂重构为天然纳米盘 | Ren, Q. | N/A | DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides | |
| 乳腺癌细胞中CD14的异常表达与不良预后相关。 | Katayama, H. | N/A | Aberrant expression of CD14 in breast tumor cells is associated with poor outcome | |
| Adducins 在新生皮层神经发生过程中调节神经前体细胞的形态和命运 | Ossola, C. | N/A | Adducins regulate morphology and fate of neural progenitors during neocortical neurogenesis | |
| 斑马鱼嗅上皮中的成对和单独离子细胞 | Peloggia, J. | N/A | Paired and solitary ionocytes in the zebrafish olfactory epithelium | |
| BLAKOR对BNST的输入调控社会压力加剧的酒精摄入 | Maiya, R. | N/A | BLAKOR inputs to the BNST regulate social stress-escalated alcohol consumption | |
| CA2锥体细胞和表达Parvalbumin的细胞上的神经周网对海马依赖性记忆的调节作用不同。 | Alexander, G. M. | N/A | Perineuronal nets on CA2 pyramidal cells and parvalbumin-expressing cells differentially regulate hippocampal dependent memory | |
| 使用荧光图像中的非均匀背景减除法进行即时早期基因表达神经元的自动细胞检测 | Osanai, H. | N/A | Automated cell detection for immediate early gene-expressing neurons using inhomogeneous background subtraction in fluorescent images | |
| Ccp1的耗竭破坏了海马区小清蛋白中间神经元的网络整合 | Le Bail, R. | N/A | Ccp1 depletion disrupts network integration of hippocampal parvalbumin interneurons | |
| 青春期服用激素避孕药与ABCD研究中皮质脑测量结果的关系 | Heller, C. | N/A | Hormonal contraceptive intake during adolescence and cortical brain measures in the ABCD Study | |
| 皮质在动作停止中的注意定向和反应取消中的贡献 | Kemp, S. A. | N/A | Cortical contributions to attentional orienting and response cancellation in action stopping | |
| 周围神经损伤后，施万细胞调控轴突球体 | Hunter-Chang, S. | N/A | Axonal spheroids are regulated by Schwann cells after peripheral nerve injury | |
| 卷积神经网络模型描述了听觉皮层中局部电路的编码子空间 | Wingert, J. C. | N/A | Convolutional neural network models describe the encoding subspace of local circuits in auditory cortex | |
| 应用RID-Rihaczek相位同步方法于静息状态脑电图：同时预测视空间追踪、语言交流、执行功能、神经认知健康及智力 | Miyatsu, T. | N/A | RID-Rihaczek Phase Synchrony Method Applied to Resting-State EEG: Simultaneous prediction of visuospatial tracking, verbal communication, executive function, neuro-cognitive health, and intelligence | |
| 病理性tau改变头部方向信号并导致空间定向障碍 | Jiang, S. | N/A | Pathological tau alters head direction signaling and induces spatial disorientation | |
| 心理任务引起大脑皮层和脊髓中振荡的共同调节 | Ofner, P. | N/A | Mental Tasks Induce Common Modulations of Oscillations in Cortex and Spinal Cord | |
| 突然的感觉事件会在小鼠新皮层的各层中引发与感觉模式无关的反应 | Benusiglio, D. | N/A | Sudden sensory events trigger modality-independent responses across layers in the mouse neocortex | |
| 供体胚胎干细胞通过拥挤和FGF4信号传导，在8细胞阶段嵌合体中阻碍宿主外胚层细胞的特化。 | Strawbridge, S. E. | N/A | Donor embryonic stem cells impede host epiblast specification in 8-cell stage chimeras by crowding and FGF4 signalling | |
| 在胚胎神经发生过程中线粒体分配不均 | Bunel, B. | N/A | Uneven mitochondrial segregation during embryonic neurogenesis | |
| 时空调控的母源性RNA在小鱼胚胎发生中的关键作用 | Kushawah, G. | N/A | Critical role of Spatio-Temporally Regulated Maternal RNAs in Zebrafish Embryogenesis | |
| RBPMS与RBPMS2协同作用以保护心脏剪接 | Wu, T. | N/A | RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing | |
| 表皮PRMT5的丧失导致非典型基底角质形成细胞样细胞群的出现及皮肤分层缺陷 | Recka, N. M. | N/A | Epidermal loss of PRMT5 leads to the emergence of an atypical basal keratinocyte-like cell population and defective skin stratification | |
| BumbleBox：一个用于量化熊蜂群落行为的开源平台 | Easton-Calabria, A. C. | N/A | The BumbleBox: An open-source platform for quantifying behavior in bumblebee colonies | |
| 尾标系统：利用ArUco标记在复杂环境中长期追踪多只小鼠。 | Coulombe, V. | N/A | The Tailtag System: Tracking Multiple Mice in a Complex Environment Over a Prolonged Period Using ArUco Markers. | |
| 滤泡性Bcl6反应性与COVID-19中独特的免疫景观和空间转录组相关 | Brenna, C. | N/A | Follicular Bcl6 reactivity is associated with a unique immune landscape and spatial transcriptome in COVID-19 | |
| 留尼汪岛白纹伊蚊和致倦库蚊病毒群落的对比研究 | Francois, S. | N/A | Contrasted viral communities between Aedes albopictus and Culex quinquesfasciatus in La Reunion Island | |
| 甲烷氧化菌Ca. Methanoperedens在混层湖Cadagno沉积物中的甲烷氧化适应性及其与硫酸盐还原菌的相互作用 | Echeveste Medrano, M. J. | N/A | Methanotrophic flexibility of Ca. Methanoperedens and its interactions with sulfate-1 reducing bacteria in the sediment of meromictic Lake Cadagno | |
| SARS-CoV-2轻度疾病后的谱系特异性中和抗体。疫苗接种的免疫增强效果 | Davina-Nunez, C. | N/A | Lineage-specific neutralising antibodies after SARS-CoV-2 mild disease. Immune boosting effect of vaccination | |
| 可溶性电子穿梭体对微生物铁还原和产甲烷的影响 | Thapa, B. S. | N/A | Effects of Soluble Electron Shuttles on Microbial Iron Reduction and Methanogenesis | |
| 开发一种新的N-端组学方法以研究金黄色葡萄球菌V8蛋白酶在人中性粒细胞中的病原降解组 | Mustor, E. M. | N/A | Development of a New N-Terminomic Method to Study the Pathodegradome of the Staphylococcus aureus V8 Protease in Human Neutrophils | |
| 弓形虫感染神经元会改变细胞外囊泡的产生和内容物，进而改变星形胶质细胞的表型，并导致感染脑中GLT-1的丢失。 | Tabaie, E. Z. | N/A | Toxoplasma gondii infection of neurons alters the production and content of extracellular vesicles altering astrocyte phenotype and contributing to the loss of GLT-1 in the infected brain | |
| 淡水厌氧甲烷氧化古菌暴露于硫化物时的生理应激反应 | Echeveste Medrano, M. J. | N/A | Physiological stress response to sulfide exposure of freshwater anaerobic methanotrophic archaea | |
| TlpD胞内化学感受器的C端促进极性定位与功能 | Lopez-Magana, R. | N/A | The C-terminus of the TlpD cytoplasmic chemoreceptor promotes polar localization and function | |
| 流感病毒通过削弱中性粒细胞介导的通过胶囊受体捕获细菌的能力，增强了细菌在肺部的生长。 | Fang, Y. | N/A | Influenza Virus Enhances Bacterial Growth in the Lungs through Weakening Capsule Receptor-Mediated Bacterial Capture by Neutrophils | |
| SARS-CoV-2 JN.1揭示了其致病性减弱和空气传播的特性。 | Liu, R. | N/A | SARS-CoV-2 JN.1 reveals attenuated pathogenicity and airborne transmission | |
| 南非2024年猴痘分子流行病学初步报告 | Featherston, J. | N/A | Preliminary report on the molecular epidemiology of mpox, South Africa 2024 | |
| 基于捕获离子迁移技术的空间蛋白质组学与MALDI MS/MS成像：多重化和空间肽鉴定的初步观察 | Li, M. J. | N/A | Spatial Proteomics by Trapped Ion Mobility supported MALDI MS/MS Imaging: A First Glance into Multiplexed and Spatial Peptide Identification | |
| 通过稳定性/溶解度改变探索组合疗法的作用机制：推进AML治疗 | Gholizadeh, E. | N/A | Exploring Mechanisms of Action in Combinatorial Therapy through Stability/Solubility Alterations: Advancing AML Treatment | |
| 生化、结构及单分子技术对LIG1活性位点突变体的表征表明，F635和F872残基在确保准确连接过程中起关键作用。 | Kalaycioglu, M. | N/A | Biochemical, structural, and single-molecule characterization of LIG1 active site mutants demonstrate role of F635 and F872 residues for faithful ligation | |
| 优化生物液体和细胞外囊泡的脂质组学分析工作流程：采用集成液相色谱-串联质谱方法 | Vilela, A. F. L. | N/A | Optimizing Lipidomics Analysis Workflows for Biological Fluids and Extracellular Vesicles with Integrated Liquid Chromatography Tandem Mass Spectrometry Approaches | |
| DNA StairLoop：在基于DNA的数据存储中实现高纠错和并行处理能力 | Yan, Z. | N/A | DNA StairLoop: Achieving High Error-correcting and Parallel-processing Capabilities in DNA-based Data Storage | |
| 利用分裂重组酶实现复杂的视神经空间模式化 | Kinstlinger, I. S. | N/A | Complex optogenetic spatial patterning with split recombinase | |
| 细胞生长周期中重组酶活性的表征 | Macia, J. | N/A | CHARACTERIZATION OF RECOMBINASE ACTIVITY ACROSS CELLULAR GROWTH PHASES | |
| 微生物合作伙伴（MiPner）分析 | Bennetzen, J. L. | N/A | Microbial Partner (MiPner) Analysis | |
| Hsp20的细胞月光化功能指导了Ustilago maydis的形态和致病性发展 | Mitra, A. | N/A | Cellular moonlighting function of Hsp20 directs morphological and pathogenic development in Ustilago maydis | |
| 巴基斯坦托巴·泰克辛地区后院鸽子、鸭子和鸡中禽流感的流行率及风险因素 | Shakeel, I. | N/A | Prevalence and risk factors for avian influenza in backyard pigeons, ducks, and chickens in District Toba Tek Singh Pakistan | |
| 增强和验证基于云的结核杆菌遗传处理平台对抗生素耐药性预测性能 | Westhead, J. | N/A | Enhancement and validation of the antibiotic resistance prediction performance of a cloud-based genetics processing platform for Mycobacteria | |
| 通过AlsE利用替代甜味剂D-阿洛酮糖的肠道微生物群 | Ndjite, G. M. | N/A | Gut Microbial Utilization of the Alternative Sweetener, D-Allulose, via AlsE | |
| 评估在实际相关条件下，传统和可持续水泥基材料制成的表面上大肠杆菌的存活与去除情况 | Anderson, C. E. | N/A | Evaluating the Survival and Removal of Escherichia coli from Surfaces Made with Traditional and Sustainable Cement-Based Materials in Field-Relevant Conditions | |
| 一种多价适配机制驱动蛋白酶体的核输入 | Brunner, H. L. | N/A | A multivalent adaptor mechanism drives the nuclear import of proteasomes | |
| 神经肽在切叶蚁Atta cephalotes的劳动分工中起着特化和重编程的作用。 | Gilbert, M. B. | N/A | Neuropeptides specify and reprogram division of labor in the leafcutter ant Atta cephalotes | |
| 优化牛细胞基因编辑：Cas9变体与CRISPR递送方法的比较研究 | Du, X. | N/A | Optimizing Genome Editing in Bovine Cells: A Comparative Study of Cas9 Variants and CRISPR Delivery Methods | |
| KDM5C是一种性别偏向的制动器，抑制了体细胞谱系中生殖系基因表达程序的激活。 | Bonefas, K. M. | N/A | KDM5C is a sex-biased brake against germline gene expression programs in somatic lineages | |
| 一种机器学习分类器，用于识别和优先处理与心脏发育相关的基因 | Kabir, M. | N/A | A Machine Learning Classifier to Identify and Prioritise Genes Associated with Cardiac Development | |
| 小脑-前额叶连接预测精神病谱系中阴性症状的严重程度 | Yarrell, S. A. | N/A | Cerebellar-Prefrontal Connectivity Predicts Negative Symptom Severity Across the Psychosis Spectrum | |
| TRPV4通道有助于主动脉根部硬化和动脉粥样硬化病变的发展。 | Rahaman, S. G. | N/A | TRPV4 channel contributes to aortic root stiffening and atherosclerotic lesion development | |
| # BioRxiv 2024-11-07 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 后鼻皮层中的神经元在视觉双条件辨别过程中编码非空间背景信息。 | Heimer-McGinn, V. R. | N/A | Neurons in the postrhinal cortex encode nonspatial context during visual biconditional discrimination | |
| 利用极值统计学将精神病理学重新概念化为偏离规范参考模型的极端偏差 | Fraza, C. J. | N/A | Using extreme value statistics to reconceptualize psychopathology as extreme deviations from a normative reference model | |
| 人类细胞中以启动子为中心的相互作用的全基因组核小体分辨率图谱证实了增强子-启动子环路模型。 | Golov, A. K. | N/A | A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping model | |
| 多感官整合增强了Mauthner细胞的视听反应 | Otero Coronel, S. | N/A | Multisensory integration enhances audiovisual responses in the Mauthner cell | |
| 多研究fMRI展望在停止信号范式中的皮层下BOLD反应 | Isherwood, S. J. S. | N/A | Multi-study fMRI outlooks on subcortical BOLD responses in the stop-signal paradigm | |
| 栖息地结构复杂性通过减轻食人行为，增加了米氏野鲮鱼的年龄阶梯共存和种群增长率。 | Edeline, E. | N/A | Habitat structural complexity increases age-class coexistence and population growth rate through relaxed cannibalism in medaka fish | |
| 极性交替结合化学和机械信号，驱动组织形态发生 | Osterfield, M. | N/A | Alternating polarity integrates chemical and mechanical cues to drive tissue morphogenesis | |
| 篮蛤（Clinocardium nuttallii）中存在多条可传播的肿瘤谱系，并反复发生线粒体DNA的水平转移 | Yonemitsu, M. A. | N/A | Multiple lineages of transmissible neoplasia in the basket cockle (Clinocardium nuttallii) with repeated horizontal transfer of mitochondrial DNA | |
| 驱动幼年斑马鱼浦肯野细胞紧张性放电的离子电导 | Jadhav, M. P. | N/A | Ionic conductances driving tonic firing in Purkinje neurons of larval zebrafish | |
| 乳腺癌细胞以依赖MRTF的旁分泌方式促进破骨细胞分化 | Chawla, P. | N/A | Breast cancer cells promote osteoclast differentiation in an MRTF-dependent paracrine manner | |
| NRPS基因赋予新型枯草芽孢杆菌和类芽孢杆菌菌株抗真菌活性，并在植物病原体存在下以菌株特异性的方式改变其表达。 | Vasilchenko, N. | N/A | NRPS genes provide antifungal activity to new Bacillus and Paenibacillus strains and change their expression in the presence of phytopathogens in a strain-specific manner | |
| 铜绿假单胞菌极性鞭毛组装的时空和数量调控 | Pulido-Sanchez, M. | N/A | Spatial, temporal and numerical regulation of polar flagella assembly in Pseudomonas putida | |
| 单一的计算目标驱动着视觉皮层中流的专业化 | Finzi, D. | N/A | A single computational objective drives specialization of streams in visual cortex | |
| CtBP的破坏调控了小鼠胚胎干细胞中依赖和不依赖DUX的2细胞样状态的遗传程序 | Sugiyama, K. | N/A | The disruption of CtBP regulates DUX-dependent and -independent genetic program for the 2-cell-like state in murine embryonic stem cells | |
| 发现高吞吐量扰动下的根因基因 | Strobl, E. V. | N/A | Discovering Root Causal Genes with High Throughput Perturbations | |
| 矛盾中的导航：鼠伤寒沙门氏菌对冲突效应刺激的趋化反应 | Franco, K. M. | N/A | Navigating contradictions: Salmonella Typhimurium chemotactic responses to conflicting effector stimuli | |
| 利用表观基因组数据在农场动物中注释和评估调控区域的功能变异 | Ma, R. | N/A | Annotation and assessment of functional variants in regulatory regions using epigenomic data in farm animals | |
| 头足类性别的决定及其古老的进化起源 | Coffing, G. C. | N/A | Cephalopod Sex Determination and its Ancient Evolutionary Origin | |
| 单细胞中基因表达与染色质可及性的灵活且高通量同时分析 | Soltys, V. | N/A | Flexible and high-throughput simultaneous profiling of gene expression and chromatin accessibility in single cells | |
| 外代谢物的季节性模式取决于寡营养海洋中的微生物功能 | McParland, E. L. | N/A | Seasonal patterns of exometabolites depend on microbial functions in the oligotrophic ocean | |
| 跨物种感知证据积累研究框架 | Chakravarty, S. | N/A | A cross-species framework for investigating perceptual evidence accumulation | |
| 葡聚糖硫酸钠诱导的肠道炎症及其全身效应的空间映射 | Adams, L. | N/A | Spatial mapping of dextran sodium sulphate-induced intestinal inflammation and its systemic effects | |
| 一项多学科的玉米-豆类间作田间调查突显了振兴传统农业系统的关键考量。 | Vazeux-Blumental, N. | N/A | A multidisciplinary on-farm survey of maize-bean intercropping highlights key considerations for reviving traditional agricultural systems. | |
| 新型酿酒酵母共生体生态学研究发酵模型设计 | Pourcelot, E. | N/A | Design of a new model yeast consortium for ecological studies of enological fermentation | |
| 表皮胶原蛋白减少驱动感觉神经元衰老的特定方面 | Krishna, M. | N/A | Epidermal Collagen Reduction Drives Selective Aspects of Aging in Sensory Neurons | |
| 带标签的分子生物学并行最大公共子图 | Agbeto, W. | N/A | Parallel maximal common subgraphs with labels for molecular biology | |
| 祁连山高山草甸多年冻土融化梯度上表层土壤细菌和微真核生物的组成变化及共现模式 | Wang, Z. | N/A | Compositional Shifts and Co-occurrence Patterns of Topsoil Bacteria and Micro-Eukaryotes Across a Permafrost Thaw Gradient in Alpine Meadows of the Qilian Mountains, China | |
| 氧化型低密度脂蛋白通过AT1-LOX1受体复合物增强血管紧张素II诱导的Gq激活：对肾功能障碍的启示 | Ihara, J. | N/A | Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction | |
| 基于全脑细胞c-Fos表达成像的精神药物分类 | Aboharb, F. | N/A | Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression | |
| 探索进化以揭示蛋白质突变稳定性的见解 | Hermans, P. | N/A | Exploring evolution to uncover insights into protein mutational stability | |
| 与生物入侵过程中的适应性进化相关的花序展示的纬度梯度变化 | Akbar, M. | N/A | Latitudinal clines in floral display associated with adaptive evolution during a biological invasion | |
| 个性化计算模型以构建医疗数字孪生 | Knapp, A. C. | N/A | Personalizing computational models to construct medical digital twins | |
| 揭示转座子编码的Cascade-TniQ复合物中的Cas8动态与调控 | Patel, A. C. | N/A | Unveiling Cas8 Dynamics and Regulation within a transposon-encoded Cascade-TniQ Complex | |
| 在斑马鱼中进行尖锐的分析，作为快速功能筛选脆性骨病致病基因的工具 | Debaenst, S. | N/A | Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for bone fragility | |
| 将选择与种群动态联系起来：单细胞生物主动死亡实验进化的研究 | Zeballos, N. | N/A | Linking selection to demography in experimental evolution of active death in a unicellular organism | |
| 大肠杆菌表观转录组直接RNA测序揭示了热应激下的变化 | Riquelme-Barrios, S. | N/A | Direct RNA sequencing of the Escherichia coli epitranscriptome uncovers alterations under heat stress | |
| 人口连接场建模揭示了胎儿人脑中原始视网膜拓扑视觉皮层组织 | Yoo, S.-H. | N/A | Population connective field modeling reveals proto-retinotopic visual cortex organization in the prenatal human brain | |
| 通过CDK12/7/9降解诱导急性BRCAness并阻断AR信号传导，增强前列腺癌对PARP抑制剂的敏感性 | Gui, F. | N/A | Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer | |
| 早期和延迟的STAT1依赖性反应驱动脾脏巨噬细胞的局部训练免疫 | Solomon, A. | N/A | Early and Delayed STAT1-Dependent Responses Drive Local Trained Immunity of Macrophages in the Spleen | |
| 外毛细胞搅动耳蜗内的液体。 | Lee, C. | N/A | Outer hair cells stir cochlear fluids | |
| 在学习过程中，下边缘皮质神经元集群编码减弱了恐惧泛化表达 | Subramanian, R. | N/A | An Infralimbic Cortex Neuronal Ensemble Encoded During Learning Attenuates Fear Generalization Expression | |
| 使用生物物理模型理解多电极视网膜上刺激的响应 | Vilkhu, R. S. | N/A | Understanding responses to multi-electrode epiretinal stimulation using a biophysical model | |
| 致癌代谢物D-2-羟基戊二酸在IDH突变型胶质瘤中促进控制小胶质细胞激活的谱系特异性增强子的DNA高甲基化。 | Laurenge, A. | N/A | The oncometabolite D-2-hydroxyglutarate promotes DNA hypermethylation at lineage-specific enhancers controlling microglial activation in IDHmut gliomas | |
| 乙醇通过限制蒸腾作用减少葡萄藤的水分消耗。 | Ait Kaci, N. | N/A | Ethanol reduces grapevine water consumption by limiting transpiration | |
| 利用非扩散性邻近标记系统在活细胞和生物体内鉴定目标蛋白 | Sun, Y. | N/A | Target protein identification in live cells and organisms with a non-diffusive proximity tagging system | |
| 双壳纲基因组多样性的起源与功能意义 | Liu, S. | N/A | The origins and functional significance of bivalve genome diversity | |
| 经颅电刺激中的前庭参与：身体摇晃作为无意刺激的标志 | Laakso, I. | N/A | Vestibular involvement in transcranial electrical stimulation: body sway as a marker of unintended stimulation | |
| 金黄色葡萄球菌噬菌体phi812的细胞附着与尾部收缩 | Binovsky, J. | N/A | Cell attachment and tail contraction of S. aureus phage phi812 | |
| 芳香烃受体在平滑肌细胞中保护免受二噁英诱导的动脉粥样硬化不良重塑的影响 | Qin, G. | N/A | Aryl-hydrocarbon receptor in smooth muscle cells protect against dioxin induced adverse remodeling of atherosclerosis | |
| 组织驻留记忆CD4+ T细胞的维持依赖于特定部位的自我更新水平以及来自前体的替代。 | Chandler, J. | N/A | Tissue resident memory CD4+ T cells are sustained by site-specific levels of self-renewal and replacement from precursors | |
| 大麻烟雾和口服Δ9THC能增强老年受试者的工作记忆，但对年轻成年受试者则不然。 | Zequeira, S. | N/A | Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects | |
| ExEnDiff：一种实验引导的扩散模型，用于蛋白质构象集合生成 | Liu, Y. | N/A | ExEnDiff: An Experiment-guided Diffusion model for protein conformational Ensemble generation | |
| 神经调节对沿单一模式-跨模式梯度传播的脑波的影响 | Maki-Marttunen, V. | N/A | Neuromodulatory influences on propagation of brain waves along the unimodal-transmodal gradient | |
| 利用单细胞RNA测序生成稳健的微胶质细胞衰老时钟 | Stanley, N. | N/A | Leveraging Single-Cell RNA-Seq to Generate Robust Microglia Aging Clocks | |
| pLM-DBPs：利用蛋白质语言模型嵌入增强植物中DNA结合蛋白预测 | Pokharel, S. | N/A | pLM-DBPs: Enhanced DNA-Binding Protein Prediction in Plants Using Embeddings From Protein Language Models | |
| 有丝分裂后依赖PP2A-Ankle2的核重构机制 | Li, J. | N/A | Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis | |
| 通过超快速生物过程减轻一氧化二氮排放，实现高浓度N2O的去除 | Maeda, R. | N/A | Mitigating nitrous oxide emission by an ultra-fast bioprocess enabling the removal of high concentration N2O | |
| 查尔酮异构酶的自然变异定义了一个主要位点，控制着黑杨种群间生长变异 | Durufle, H. | N/A | Natural variation in chalcone isomerase defines a major locus controlling growth variation between Populus nigra populations | |
| 生物医学数据的AI准备度：Bridge2AI的建议 | Clark, T. | N/A | AI-readiness for Biomedical Data: Bridge2AI Recommendations | |
| 中剂量照射损害长期造血干细胞功能及对细胞毒性压力的造血恢复能力 | Zhang, Q. | N/A | Medium-dose irradiation impairs long-term hematopoietic stem cell functionality and hematopoietic recovery to cytotoxic stress | |
| 增强型Nme2Cas9和Nme2SmuCas9核酸酶及碱基编辑器的合理设计 | Bamidele, N. | N/A | Rational Design of Enhanced Nme2Cas9 and Nme2SmuCas9 Nucleases and Base Editors | |
| 开发一种用于在聚球藻PCC 6803中靶向基因上调的CRISPR激活系统 | Bourgade, B. | N/A | Development of a CRISPR activation system for targeted gene upregulation in Synechocystis sp. PCC 6803 | |
| 简化胎鼠影像中的不对称量化：基于专家指导的半自动化流程 | Rolfe, S. M. | N/A | Streamlining Asymmetry Quantification in Fetal Mouse Imaging: A Semi-Automated Pipeline Supported by Expert Guidance | |
| BC-Design：一种高度准确的逆蛋白质折叠生物化学感知框架 | Tang, X. | N/A | BC-Design: A Biochemistry-Aware Framework for Highly Accurate Inverse Protein Folding | |
| 从父母谈判策略的演变中出现的替代后代抚养模式 | Zheng, J. | N/A | Emergence of alternative offspring care patterns from the evolution of parental negotiation strategies | |
| 通过X射线晶体学鉴定出的电压门控钠通道中对挥发性麻醉剂具有功能重要性的结合位点 | Hollingworth, D. | N/A | Functionally important binding site for a volatile anesthetic in a voltage-gated sodium channel identified by X-ray crystallography | |
| 维生素B12通过改善丙酸分解和一碳循环代谢途径，部分挽救了秀丽隐杆线虫Ephrin突变体胚胎细胞迁移缺陷。 | Ganjawala, T. H. | N/A | Vitamin B12 partially rescues embryonic cell migration defects in C. elegans ephrin mutants by improving both propionic acid breakdown and one-carbon cycle metabolic pathways | |
| 淋巴细胞减少促使T细胞耗竭在免疫缺陷型STING功能获得性小鼠中 | Freytag, D. | N/A | Lymphopenia drives T cell exhaustion in immunodeficient STING gain-of-function mice | |
| Vcfexpress：灵活、快速的用户表达式，用于过滤和格式化VCF文件 | Pedersen, B. S. | N/A | Vcfexpress: flexible, rapid user-expressions to filter and format VCFs | |
| 一项跨研究的转录性心力衰竭患者图谱定义了心脏重塑中保守的多细胞协调机制。 | Lanzer, J. D. | N/A | A cross-study transcriptional patient map of heart failure defines conserved multicellular coordination in cardiac remodeling | |
| 随着时间的推移，音乐中概念形成的中枢机制 | Bonetti, L. | N/A | The neural mechanisms of concept formation over time in music | |
| 非重组基因组中因净化选择引起的Hill-Robertson干扰模型 | Becher, H. | N/A | A model of Hill-Robertson interference caused by purifying selection in a non-recombining genome | |
| 使用EquiRep从含有错误的高错误率序列中准确检测串联重复序列 | Song, Z. | N/A | Accurate Detection of Tandem Repeats from Error-Prone Sequences with EquiRep | |
| Metapredict能够在生命之树的各个分支上实现准确的失序预测。 | Lotthammer, J. M. | N/A | Metapredict enables accurate disorder prediction across the Tree of Life | |
| 自闭症谱系障碍中的从头结构变异破坏了神经元基因的远端调控相互作用 | Gjoni, K. | N/A | De novo structural variants in autism spectrum disorder disrupt distal regulatory interactions of neuronal genes | |
| 可重复处理的TCGA调控网络 | Fanfani, V. | N/A | Reproducible processing of TCGA regulatory networks | |
| 超-k-mers：高效的流式k-mers表示 | Martayan, I. | N/A | Hyper-k-mers: efficient streaming k-mers representation | |
| 解读功能性分化初始T细胞亚群背后的基因调控程序 | Zhu, H. | N/A | Deciphering gene regulatory programs underlying functionally divergent naive T cell subsets | |
| 睡眠期间Sigma频段功率的慢波波动：与觉醒标志及记忆再激活在发育过程中的关联 | Dimitriades, M. E. | N/A | The Infraslow Fluctuation of Sigma Power During Sleep: Links to Markers of Arousal and Memory Reactivation Across Development | |
| 基于单个神经元活动的前额叶皮层图谱 | Le Merre, P. | N/A | A Prefrontal Cortex Map based on Single Neuron Activity | |
| 小鼠情景记忆样记忆发展的敏感期 | Ramsaran, A. I. | N/A | A sensitive period for the development of episodic-like memory in mice | |
| "小动作，大影响：早期短暂运动训练对小鼠神经肌肉发育的影响" | Quilgars, C. | N/A | When Little Means a Lot: Impact of a Brief Early-life Motor Training on Mouse Neuromuscular Development. | |
| 调节注意力网络中依赖学习的可塑性 | Conto', F. | N/A | Modulation of learning-dependent plasticity in the attention network | |
| 欧洲西尼罗河病毒传播的生物气候模型，特别关注乌克兰 | Mezhzherin, S. | N/A | Bioclimatic modelling of the spread of the West Nile virus in Europe, with a special focus on Ukraine | |
| 社区保守性在微生物门类和环境中普遍存在。 | Malfertheiner, L. | N/A | Community conservatism is widespread throughout microbial phyla and environments | |
| 现代人类生殖基因中的古适应性渗入 | Kendall, C. J. R. | N/A | Archaic Adaptive Introgression in Modern Human Reproductive Genes | |
| 基因重复后表达变异性的增加有助于基因的保留 | Cai, H. | N/A | Expression variability following gene duplication facilitates gene retention | |
| 干细胞性预测模型揭示了胶质瘤的侵袭性及治疗靶点 | Simoes, R. d. L. S. | N/A | Stemness prediction models reveal glioma aggressiveness and therapeutic targets in gliomas | |
| 高质量的大规模开花沙漠植物Cistanthe longiscapa的基因组及其与干旱和生命史相关的光合作用行为 | Chomentowska, A. | N/A | A high-quality genome of the mass-blooming desert plant Cistanthe longiscapa and its photosynthetic behavior related to drought and life history | |
| 人类小脑和腹侧被盖区在习得性恐惧消退过程中相互作用 | Nio, E. | N/A | Human cerebellum and ventral tegmental area interact during extinction of learned fear | |
| TIA1介导了小胶质细胞和巨噬细胞对Tau病的不同炎症反应 | Webber, C. J. | N/A | TIA1 Mediates Divergent Inflammatory Responses to Tauopathy in Microglia and Macrophages | |
| 源自汉坦病毒的肽段能够稳定HLA-E，从而解除CD56dimNKG2A+ NK细胞的抑制作用。 | Manling, X. | N/A | Hantaan virus-derived peptides that stabilize HLA-E could abrogate inhibition of CD56dimNKG2A+ NK cells | |
| 鹦鹉发声生产学习的演变 | Krasheninnikova, A. | N/A | Evolution of vocal production learning in parrots | |
| 社会性如何影响繁殖者对恶劣热环境的适应性反应？埋葬甲虫的一项实验 | Ma, D. | N/A | Sociality shapes the adaptive response of breeders to harsh thermal environments? An experiment in a burying beetle | |
| 禾本科姐妹基因组揭示了草类出现前的关键代谢创新 | Takeda-Kimura, Y. | N/A | Genomes of Poaceae sisters reveal key metabolic innovations preceding the emergence of grasses | |
| PLM-interact：扩展蛋白质语言模型以预测蛋白质-蛋白质相互作用 | Liu, D. | N/A | PLM-interact: extending protein language models to predict protein-protein interactions | |
| GenomicSign：一种用于发现目标基因组序列的独特、特异且可扩增的特征的计算方法 | Kumar S, P. | N/A | GenomicSign: A computational method to discover unique, specific, and amplifiable signatures of target genomic sequences | |
| 湿度感应受损通过阻止水分平衡，降低了蜱的存活率。 | Uhran, M. R. | N/A | Impaired humidity sensing reduces tick survival by preventing water homeostasis | |
| 从单次MRI估计的终身脑萎缩：测量特征和全基因组关联 | Fürtjes, A. E. | N/A | Lifetime brain atrophy estimated from a single MRI: measurement characteristics and genome-wide correlates | |
| NOLC1通过抑制p53介导的铁死亡在胃癌中抑制免疫化疗 | Zhao, S. | N/A | NOLC1 Suppresses Immuno-chemotherapy by Inhibiting p53-mediated Ferroptosis in Gastric Cancer | |
| 差异性KEAP1/NRF2介导的信号传导扩大了氧化还原靶向药物在SCLC治疗中的治疗窗口 | Samarin, J. | N/A | Differential KEAP1/NRF2 mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy | |
| 在使用Parsortix系统观察胰腺癌细胞系时发现的偏差 | Vandenbussche, N. | N/A | Biases in the Parsortix system observed with pancreatic cancer cell lines | |
| 从小鼠成纤维细胞诱导生成具有致癌性的多能干细胞 | Shabrish, S. | N/A | Induction of pluripotent oncogenic stem cells from mouse fibroblasts | |
| 抑制p38-MK2通路可增强微管抑制剂在乳腺癌细胞中的疗效 | Chen, Y.-C. | N/A | Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells | |
| 差异表达的生长因子和细胞因子驱动可传播癌症的表型变化 | Maskell, K. G. | N/A | Differentially expressed growth factors and cytokines drive phenotypic changes in transmissible cancers | |
| 最大化减数分裂交叉率揭示了交叉潜能图谱 | Jing, J. | N/A | Maximizing meiotic crossover rate reveals the map of Crossover Potential | |
| 来自不动杆菌属的OXA β-内酰胺酶是膜结合的，并被分泌到外膜囊泡中。 | Capodimonte, L. | N/A | OXA beta-lactamases from Acinetobacter spp. are membrane-bound and secreted into outer membrane vesicles | |
| 抑制和更新共享资源：来自漂移扩散模型的证据 | Sun, Y. | N/A | Inhibition and Updating Share Common Resources: Evidence from Drift Diffusion Model | |
| 静息态连接改变淀粉样蛋白对认知和身体功能的影响：基于网络的认知储备证据 | Laurienti, P. J. | N/A | Resting-state connectivity modifies the effects of amyloid on cognitive and physical function: evidence for network-based cognitive reserve | |
| p.A53T-α-突触核蛋白诱导多能干细胞衍生的星形胶质细胞中的蛋白质稳态失调加剧了具有类Lewy病理的帕金森病模型中的神经退行性变 | Paschou, C. | N/A | Proteostasis dysregulation in p.A53T-α-Synuclein iPSC-derived astrocytes exacerbates neurodegeneration in a Parkinson's disease model with Lewy-like pathology | |
| 电协调重置刺激在癫痫持续状态的体内模型中诱导网络去同步化 | Ehrens, D. | N/A | Electrical Coordinated Reset Stimulation Induces Network Desynchronization in an in Vivo Model of Status Epilepticus | |
| 概率编程语言中的动态因果建模 | Baldy, N. | N/A | Dynamic Causal Modeling in Probabilistic Programming Languages | |
| 单目标光片显微镜可实现果蝇活体脑部的高分辨率成像。 | Tassara, F. J. | N/A | Single Objective Light Sheet Microscopy allows high-resolution in vivo brain imaging of Drosophila. | |
| 医学：神经电生理记录的运动校正 | Watters, N. | N/A | MEDiCINe: Motion Correction for Neural Electrophysiology Recordings | |
| 评估使用扩散去噪概率模型生成的合成扩散磁共振成像图谱 | Chattopadhyay, T. | N/A | Evaluating Synthetic Diffusion MRI Maps created with Diffusion Denoising Probabilistic Models | |
| 降低胆固醇酯转移蛋白（CETP）活性可预防阿尔茨海默病小鼠模型中的记忆衰退 | Phenix, J. | N/A | Reducing CETP activity prevents memory decline in an Alzheimer's disease mouse model | |
| 奖励性和厌恶性刺激对中央杏仁核中D1型和D2型多巴胺敏感神经元产生相反的影响 | Bijoch, L. | N/A | Opposing effects of rewarding and aversive stimuli on D1 and D2 types of dopamine-sensitive neurons in the central amygdala | |
| 海马体CA3亚区的空间编码受递归连接的影响 | Kong, E. | N/A | Recurrent Connectivity Shapes Spatial Coding in Hippocampal CA3 Subregions | |
| SMAS：基于贝叶斯VAE的结构MRI阿尔茨海默病评分 | Nemali, A. | N/A | SMAS: Structural MRI-Based AD Score using Bayesian VAE | |
| 高度社会性慈鲷下丘脑和视前区的单核转录组 | Miller-Crews, I. | N/A | Single-nuclei transcriptomes in the hypothalamus and POA of a highly social cichlid | |
| 即插即用的肌电控制通过自校准的随机森林通用模型实现 | Jiang, X. | N/A | Plug-and-Play Myoelectric Control via a Self-Calibrating Random Forest Common Model | |
| 轴突损伤信号受到保留的突触分支的抑制。 | Smithson, L. J. | N/A | Axonal injury signaling is restrained by a spared synaptic branch | |
| 昼夜结构可塑性的超微结构相关性 | Ispizua, J. I. | N/A | Ultrastructural correlates of circadian structural plasticity | |
| 全转录组小核糖体亚基图谱揭示了哺乳动物大脑中翻译起始的扫描机制 | Kute, P. | N/A | Transcriptome-wide mapping of small ribosomal subunits elucidates scanning mechanisms of translation initiation in the mammalian brain | |
| 神经元群体对相位锁定刺激的响应：基于模型的预测与验证 | Mirkhani, N. | N/A | Response of neuronal populations to phase-locked stimulation: model-based predictions and validation | |
| 嗅觉球追踪自由活动小鼠的呼吸节奏和位置 | Sterrett, S. C. | N/A | Olfactory bulb tracks breathing rhythms and place in freely behaving mice | |
| 统一海马旁区功能：一种预测图谱方法 | Bennett, L. | N/A | Unifying Subicular Function: A Predictive Map Approach | |
| 将生物性别作为主要变量可能会限制我们对精神兴奋剂活动中行为多样性（及性别差异）的理解。 | Yao, G. | N/A | Employing biological sex as a primary variable can restrict our understanding of behavioral diversity (and sex differences) in psychostimulant activity. | |
| 静息状态网络是大脑的认知原子吗？任务间和静息状态下功能性脑网络的动态重构差异 | Jung, J. | N/A | Are resting-state networks the brain's cognitive atoms? Differential dynamic reconfiguration of functional brain networks across tasks and at rest | |
| 通过多重CRISPR/Cas9基因编辑揭示的GABA转运体3介导的小鼠视觉皮层星形胶质细胞对群体编码的调节 | Park, J. | N/A | Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing | |
| 通过通信子空间测量神经群体之间的刺激信息传递 | Weiss, O. | N/A | Measuring Stimulus Information Transfer Between Neural Populations through the Communication Subspace | |
| 通过静息状态下的alpha动态区分幻觉倾向维度 | Honcamp, H. | N/A | Differentiating hallucination proneness dimensions through resting state alpha dynamics | |
| 一种用于增强音乐寒意体验的个性化播放列表的冷感脑机音乐接口 | Kondoh, S. | N/A | A chill brain-music interface for enhancing music chills with personalized playlists | |
| 神经损伤对小鼠蓝斑功能和行为影响的性别差异 | Mariscal, P. | N/A | Sex differences in the impact of nerve injury on Locus Coeruleus function and behaviour in mice | |
| 可卡因通过ΔFosB重塑了腹侧海马的基因表达和兴奋性 | Eagle, A. L. | N/A | Cocaine, via ΔFosB, remodels gene expression and excitability in ventral hippocampus | |
| 个性化tDCS针对视觉运动区域V5调节平滑追踪启动 | Radecke, J.-O. | N/A | Personalized tDCS targeting visual motion area V5 modulates smooth pursuit initiation | |
| 肠道微生物群调控运动诱导的激素性调节认知功能 | Cintado, E. | N/A | Gut Microbiota Regulates Exercise-induced Hormetic Modulation of Cognitive Function | |
| 电刺激期间无伪影脑电图的实时时空滤波 | Menrath, D. | N/A | Real-Time Spatiotemporal Filtering for Artifact-Free EEG during Electrical Neurostimulation | |
| BMP4足以诱导尾侧组织者 | Xu, P.-F. | N/A | BMP4 is sufficient to induce a caudal organizer | |
| Numb为成年果蝇中肠干细胞自我更新提供了一种安全保障机制。 | Li, M. | N/A | {-}Numb provides a fail-safe mechanism for intestinal stem cell self-renewal in adult Drosophila midgut | |
| FVB/N小鼠亚系在新生儿阿片戒断期间的超声发声（USVs）的声学特性、音节结构和音节序列 | Wingfield, K. K. | N/A | The acoustic properties, syllable structure, and syllable sequences of ultrasonic vocalizations (USVs) during neonatal opioid withdrawal in FVB/N mouse substrains | |
| CIFR（克隆-整合-翻转-切除-重复）：用于革兰氏阴性菌基因组和通路迭代工程的工具集 | Federici, F. | N/A | CIFR (Clone-Integrate-Flip-out-Repeat): a toolset for iterative genome and pathway engineering of Gram-negative bacteria | |
| 利用计算结构预测探索工程受体性能中的结构-功能关系 | Corcoran, W. K. | N/A | Exploring structure-function relationships in engineered receptor performance using computational structure prediction | |
| 与摄入营养性和非营养性溶液相关的组胺的快速波动 | Volcko, K. L. | N/A | Rapid fluctuations in histamine associated with intake of nutritive and non-nutritive solutions | |
| 线粒体酶GPT2的缺失导致突触谷氨酸代谢的重编程 | Baytas, O. | N/A | Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism | |
| psilocybin对前额-纹状体-丘脑回路动态连接和有效连接的长期影响 | Pasquini, L. | N/A | Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic circuits | |
| RBFOX1缺陷的纠正能够挽救亨廷顿病的错误剪接和病理 | Lozano-Munoz, D. | N/A | Correction of RBFOX1 deficit rescues Huntington's disease mis-splicing and pathology | |
| 不同同义密码子替换策略对SARS-CoV-2核衣壳蛋白在埃希氏大肠杆菌中表达的影响 | Bello, A. J. | N/A | Impact of different synonymous codon substitution strategies on SARS-CoV-2 nucleocapsid protein expression in Escherichia coli | |
| 单一嵌合刺突抗原诱导泛萨贝科病毒免疫 | Counoupas, C. | N/A | A Single Chimeric Spike Antigen Induces Pan-Sarbecovirus Immunity | |
| 了解海洋生态系统中发现的生物聚合物如何影响噬菌体对细菌的效力 | Kwack, J. | N/A | Understanding How Biopolymers Found in Marine Ecosystems Impact the Efficacy of Bacteriophages against Bacteria | |
| 通过厌氧光敏化实现产油微藻培养的阿克西尼化。 | Iyer, A. | N/A | Axenisation of oleaginous microalgal cultures via anoxic photosensitisation. | |
| 在极度濒危的鸮鹦鹉（Strigops habroptilus）中，肠道外致病性大肠杆菌、粪肠球菌和格氏链球菌在渗出性泄殖腔炎的病因学中起作用的证据 | French, R. K. | N/A | Evidence for a role of extraintestinal pathogenic Escherichia coli, Enterococcus faecalis and Streptococcus gallolyticus in the aetiology of exudative cloacitis in the critically endangered kakapo (Strigops habroptilus) | |
| 超粘液型肺炎克雷伯菌气溶胶持久性的比较研究 | Chirichella, N. | N/A | Comparative Aerosol Persistence of Hypermucoid Klebsiella pneumoniae | |
| 膜不对称性促进鼠诺如病毒的进入和持续性肠道感染 | Stewart, B. M. | N/A | Membrane asymmetry facilitates murine norovirus entry and persistent enteric infection | |
| Mla途径促进霍乱弧菌从静止期重新扩张 | Leitner, D. R. | N/A | The Mla pathway promotes Vibrio cholerae re-expansion from stationary phase | |
| 竞争策略驱动几丁质降解群落中的资源划分 | Pontrelli, S. | N/A | Competition strategies driving resource partitioning in chitin degrading communities | |
| 在亲缘关系相近的物种中，细菌伸长的表型可塑性 | Delaby, M. | N/A | Phenotypic plasticity in bacterial elongation among closely related species | |
| 醋酸通过在耐药细菌中引发渗透压失衡，协同增强掺钴碳量子点的杀菌效率。 | Truskewycz, A. | N/A | Acetic acid induces osmotic imbalances in drug-resistant bacteria synergistically enhancing cobalt-doped carbon quantum dots bactericidal efficiency | |
| 甲萘醌可降低幽门螺杆菌中与毒力和定殖相关基因的表达。 | Thompson, S. | N/A | Menadione reduces the expression of virulence- and colonisation-associated genes in Helicobacter pylori | |
| 两性霉素B增强SARS-CoV-2感染：对疾病管理的启示 | Nguyen, D. | N/A | SARS-CoV-2 infection enhancement by Amphotericin B: Implications for disease management | |
| 通过基于深度学习的结构集合解码DNA连接酶活性中的蛋白质动态性 | Mishra, N. | N/A | Decoding protein dynamicity in DNA ligase activity through deep learning-based structural ensembles | |
| Rab40 GTP酶调节AMBRA1介导的转录和细胞迁移 | Sampath, R. | N/A | Rab40 GTPases regulate AMBRA1-mediated transcription and cell migration | |
| 通过不同的DNA结合动力学实现TBP同源物的功能分化 | Cui, J. H. | N/A | Functional divergence of TBP homologs through distinct DNA binding dynamics | |
| 依赖盐的非催化变构调节：人USP14调控的26S蛋白酶体 | Zou, S. | N/A | Salt-dependent non-catalytic allostery of human USP14-regulated 26S proteasome | |
| Rad52在DNA接合处对Rad51进行分类和堆叠，以促进同源重组。 | Deveryshetty, J. | N/A | Rad52 sorts and stacks Rad51 at the DNA junction to promote homologous recombination | |
| 经过工程改造的HMGB1结构，具有串联的HMG B结构域，可促进组织再生，同时避免潜在的有害炎症或血栓形成。 | Vinals Guitart, A. | N/A | Engineered HMGB1 Construct with Tandem HMG B Domains that Promotes Tissue Regeneration without Potential for Deleterious Inflammation or Thrombosis | |
| 全面的蛋白酶特异性分析 | Zhu, B. | N/A | Comprehensive protease specificity profiling | |
| 植物中的遗传开关 | Kassaw, T. K. | N/A | A Genetic Toggle Switch in Plants | |
| 通过交替框架插入创建重叠基因 | Leonard, S. P. | N/A | Creating overlapping genes by alternate-frame insertion | |
| 粘细菌黄杆菌（Myxococcus xanthus）中分层和聚集的遗传与环境决定因素 | Khan, T. T. | N/A | Genetic and Environmental Determinants of Streaming and Aggregation in Myxococcus xanthus | |
| 细菌战与毒力和抗菌药物耐药性相关 | Sharp, C. | N/A | Bacterial warfare is associated with virulence and antimicrobial resistance | |
| 丝裂霉素C在伊利湖中以微囊藻为主的水华环境中，能够消除蓝藻的转录活动，且未检测到溶原性诱导现象。 | Martin, R. M. | N/A | Mitomycin C eliminates cyanobacterial transcription without detectable lysogen induction in a Microcystis-dominated bloom in Lake Erie | |
| 环境变化带来的压力促使一种持续性肠道病毒被清除 | Herrmann, C. | N/A | Stress from environmental change drives clearance of a persistent enteric virus | |
| 使用人源化小鼠研究ibezapolstat及其他与艰难梭菌感染相关的抗生素对微生物组的影响 | Wolfe, T. M. | N/A | Microbiome impact of ibezapolstat and other Clostridioides difficile infection relevant antibiotics using humanized mice | |
| 通过控制发酵提高毕赤酵母中免疫原性脊髓灰质炎病毒类病毒颗粒的产量 | Sherry, L. | N/A | Upscaling production of immunogenic poliovirus virus-like particles in Pichia Pastoris by controlled fermentation | |
| 夏威夷短尾鱿鱼生殖器官的组织结构和细菌微生境揭示了防御性共生的维度 | Kamp, D. | N/A | Organ structure and bacterial microbiogeography in a reproductive organ of the Hawaiian bobtail squid reveal dimensions of a defensive symbiosis | |
| Jade1与HBO1复合物是Oct4的空间选择性辅因子。 | Wu, Y. | N/A | Jade1 and the HBO1 complex are spatial-selective cofactors of Oct4 | |
| 不同营养级群体间的社会信息利用 | Muniz, M. | N/A | Social information use across trophic guilds | |
| 癫痫小鼠模型中背侧和腹侧苔藓细胞的改变与失衡 | Huang, C. S. | N/A | Alterations and Imbalance of Dorsal and Ventral Mossy Cells in a Mouse Model of Epilepsy | |
| 自噬压力在神经元中激活了不同的补偿性分泌途径 | Palumbos, S. D. | N/A | Autophagic stress activates distinct compensatory secretory pathways in neurons | |
| 人类行为中逐次试验学习后继表征 | Kahn, A. E. | N/A | Trial-by-trial learning of successor representations in human behavior | |
| 左侧弓状束的发育与阅读学习进步相关，但与数学学习无关 | Roy, E. | N/A | Development of the Left Arcuate Fasciculus is Linked to Learning Gains in Reading, but not Math | |
| 互补参考框架下时间神经表征 | Xu, Y. | N/A | Neural Representation of Time across Complementary Reference Frames | |
| 抗噬菌体防御中的淀粉样信号 | Saupe, S. J. | N/A | Amyloid signaling in antiphage defense | |
| FOXP基因调控小脑发育和进化中的浦肯野细胞多样性 | Khouri-Farah, N. | N/A | FOXP Genes Regulate Purkinje Cell Diversity in Cerebellar Development and Evolution | |
| # BioRxiv 2024-11-06 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 脊髓兴奋性增加导致运动复杂性降低 | de Graaf, M. L. | N/A | Increased spinal excitation causes decreased locomotor complexity | |
| 婴儿低频脑电皮层功率、皮层追踪和相位振幅耦合预测一年后的语言能力。 | Attaheri, A. | N/A | Infant low-frequency EEG cortical power, cortical tracking and phase-amplitude coupling predicts language a year later. | |
| 在真菌发病过程中，铁死亡的一种新型线粒体调节网络 | Shen, Q. | N/A | A novel mitochondrial regulon for Ferroptosis during fungal pathogenesis | |
| 一统天下？评估可持续森林管理指标对多分类群数据在生物多样性保护中的表现 | Paillet, Y. | N/A | One to rule them all? Assessing the performance of sustainable forest management indicators against multitaxonomic data for biodiversity conservation | |
| 光敏素将绿藻中的蓝光感知与淀粉代谢联系起来 | Yuan, Y. | N/A | Phototropin connects blue light perception to starch metabolism in green algae | |
| 逐次检测神经时间序列中的认知事件 | Weindel, G. | N/A | Trial-by-trial detection of cognitive events in neural time-series | |
| 从BioModels中筛选模型：开发创建OMEX文件的工作流程 | Xu, J. | N/A | Curating models from BioModels: Developing a workflow for creating OMEX files | |
| 一段涉及多个P450基因的基因组重复有助于登革热蚊子埃及伊蚊的杀虫剂抗性。 | Bacot, T. | N/A | A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti | |
| 将心率与自我-社交触摸区分中涉及的皮层网络动态相联系 | Candia-Rivera, D. | N/A | Linking heartbeats with the cortical network dynamics involved in self-social touch distinction | |
| ARTEM：一种用于识别RNA和DNA三级基序的方法，包括骨架排列，并举例应用于类扭结转角基序 | Baulin, E. F. | N/A | ARTEM: a method for RNA and DNA tertiary motif identification with backbone permutations, and its example application to kink-turn-like motifs | |
| 使用重组脱氧核糖核酸酶I治疗抗髓过氧化物酶肾小球肾炎，通过腺相关病毒基因疗法得到增强 | Cao Le, A. | N/A | Treatment of anti-myeloperoxidase glomerulonephritis using recombinant deoxyribonuclease I is enhanced by adeno-associated virus gene therapy | |
| 空间转录组学基因表达框架 | Cao, S. | N/A | A framework for gene representation on spatial transcriptomics | |
| 强迫性与适应性应对策略的肾上腺素能和巴甫洛夫基础 | Chernoff, C. S. | N/A | Noradrenergic and Pavlovian underpinnings of compulsive versus adaptive coping strategies | |
| FoldMark：通过水印技术保护蛋白质生成模型 | ZHANG, Z. | N/A | FoldMark: Protecting Protein Generative Models with Watermarking | |
| 偏倚校正元分析克服小脑忽视，以完善小脑行为地形图 | Magielse, N. | N/A | Bias-accounting meta-analyses overcome cerebellar neglect to refine the cerebellar behavioral topography | |
| 父母谈判策略演变中衍生出的替代后代抚养模式的出现 | Zheng, J. | N/A | Emergence of alternative offspring care patterns from the evolution of parental negotiation strategies | |
| 进化上较近的转录因子参与人类细胞周期的调控 | Pulver, C. | N/A | Evolutionarily recent transcription factors partake in human cell cycle regulation | |
| 调控转录因子（TF）-DNA相互作用的比较和群体基因组学分析 | Joshi, M. | N/A | Comparative and population genomics analyses of the regulatory Transcription Factor (TF)-DNA interaction | |
| 多样化的祖先代表性改善了遗传不耐受度量 | Han, A. | N/A | Diverse ancestral representation improves genetic intolerance metrics | |
| 单变量与多变量参考区间方法的比较 | MERGEN, E. K. | N/A | COMPARISON OF UNIVARIATE AND MULTIVARIATE REFERENCE INTERVAL METHODS | |
| 用于复杂异质性单细胞数据的标记基因捕捞 | Shao, Y. | N/A | Marker gene fishing for single-cell data with complex heterogeneity | |
| 未能考虑RNA数量会导致背景升高，并导致PRC2和GFP在体内结合RNA的误导性表象。 | Guo, J. K. | N/A | Failing to account for RNA quantity inflates background and leads to the misleading appearance that PRC2 and GFP bind to RNA in vivo | |
| 解码肝癌预后：从多组学亚型、预后模型到单细胞验证 | Wang, Y. | N/A | Decoding Liver Cancer Prognosis: From Multi-omics Subtypes, Prognostic Models to Single Cell Validation | |
| 复杂性和孟德尔性状中的多效性决定因素及其进化后果 | Barbitoff, Y. A. | N/A | Functional determinants and evolutionary consequences of pleiotropy in complex and Mendelian traits | |
| 利用可扩展的方法恢复和维持人类死后视网膜的光反应，以测试退行性疾病疗法 | Becker, S. | N/A | Restoring and sustaining human postmortem retinal light responses with scalable methods for testing degenerative disease therapies | |
| 酒精依赖戒断的神经标志物：来自奖励学习的启示 | Komarnyckyj, M. | N/A | Neural markers of abstinence in alcohol dependence: Insights from Reward Learning | |
| 两个H3K23组蛋白甲基转移酶，SET-32和SET-21，协同作用以促进在秀丽隐杆线虫中通过核RNAi介导的跨代表观遗传继承。 | Gu, S. G. | N/A | Two H3K23 histone methyltransferases, SET-32 and SET-21, function synergistically to promote nuclear RNAi-mediated transgenerational epigenetic inheritance in Caenorhabditis elegans | |
| 两种H3K23组蛋白甲基转移酶，SET-32和SET-21，在秀丽隐杆线虫中协同作用，促进核RNAi介导的跨代表观遗传继承。 | Gu, S. G. | N/A | Two H3K23 histone methyltransferases, SET-32 and SET-21, function synergistically to promote nuclear RNAi-mediated transgenerational epigenetic inheritance in Caenorhabditis elegans | |
| 孕期补充益生菌对健康人群是否安全？一项针对临床前研究的系统综述 | COCA, M. R. | N/A | Is Probiotic Supplementation During Pregnancy Safe for Healthy Populations? A Systematic Review of Preclinical Studies | |
| 神经元检测触发全身消化系统关闭，以应对不良食物来源 | Liu, Y. | N/A | Neuronal Detection Triggers Systemic Digestive Shutdown in Response to Adverse Food Sources | |
| 从开花期到高温耐受性：PHOTOPERIOD 1（PPD-H1）通过提高高温环境下的抗逆性和能量代谢来调控穗部结实率 | Lan, T. | N/A | From Flowering Time to High Temperature Resilience: PHOTOPERIOD 1 (PPD-H1) Controls Spike Fertility through Improving Stress Resistance and Energy Metabolism under High Ambient Temperatures | |
| 陆生植物特异的H3K27甲基转移酶ATXR5和ATXR6调控植物发育及胁迫响应 | Li, X. | N/A | Land plant-specific H3K27 methyltransferases ATXR5 and ATXR6 control plant development and stress responses | |
| 实时闭环反馈系统用于小鼠中尺度皮层信号与运动控制：CLoPy | Gupta, P. K. | N/A | Real-Time Closed-Loop Feedback System For Mouse Mesoscale Cortical Signal And Movement Control: CLoPy | |
| 巨噬细胞-平滑肌细胞轴通过激活EGFR途径影响大细胞性动脉炎中的血管重塑 | Chevalier, K. | N/A | A macrophage-smooth muscle cell axis influences vascular remodeling through activation of the EGFR pathway in giant cell arteritis | |
| 淋巴细胞减少促使T细胞衰竭在免疫缺陷STING功能获得性小鼠中 | Freytag, D. | N/A | Lymphopenia drives T cell exhaustion in immunodeficient STING gain-of-function mice | |
| 用于体外流感气溶胶暴露的气液界面模型 | Seibert, B. | N/A | Air-Liquid Interface Model for Influenza Aerosol Exposure In Vitro | |
| 血液点卡上动物粪便材料的DNA提取方案 | Llarena, A.-K. | N/A | DNA Extraction Protocols for Animal Fecal Material on Blood Spot Cards | |
| 通过液相色谱-串联质谱（LC-MS/MS）对mRNA中的N6-甲基腺苷和肌苷进行全球分析揭示了复杂的分布情况。 | Stejskal, S. | N/A | Global Analysis by LC-MS/MS of N6-Methyladenosine and Inosine in mRNA Reveals Complex Incidence | |
| 双CRISPR干扰策略用于靶向癌细胞中非编码RNA之间的合成致死相互作用 | Schlosshauer, J. J. | N/A | Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions between Non-Coding RNAs in Cancer Cells | |
| Vcfexpress：灵活、快速的过滤和格式化VCF的用户表达式 | Pedersen, B. S. | N/A | Vcfexpress: flexible, rapid user-expressions to filter and format VCFs | |
| 预测肿瘤突变负荷从超高频介电泳交叉频率 | Daverat, H. | N/A | Predicting Tumor Mutational Burden from UHF-Dielectrophoresis Crossover Frequency | |
| CD3、CD4和CD8的染色结果与亚洲乳腺癌患者的总体生存呈正相关，而PD-L1则不然。 | Pan, J.-W. | N/A | CD3, CD4, and CD8 staining, but not PD-L1, are positively correlated with overall survival in Asian breast cancer | |
| DNA甲基化是转移性肾细胞癌中靶向治疗和免疫检查点治疗反应的关键决定因素。 | Jeanneret, F. | N/A | DNA methylation is a key determinant of response to targeted and immune checkpoint therapies in metastatic renal cell carcinoma | |
| 解析油菜开花时间变异的分子基础 | Zhang, L. | N/A | Dissecting the molecular basis of variability for flowering time in Camelina sativa | |
| R-Loop的调控与线粒体基因组的稳定性需要5'-3'外切核酸酶/盖帽内切核酸酶OEX1的参与。 | Schatz-Daas, D. | N/A | R-Loop control and mitochondria genome stability requires the 5'-3' exonuclease/flap-endonuclease OEX1 | |
| 利用大型语言模型推进植物代谢研究：扩展数据库并提取标注数据 | Knapp, R. | N/A | Advancing Plant Metabolic Research By Using Large Language Models To Expand Databases And Extract Labelled Data | |
| 标注冷冻电镜断层成像体积：一项机器学习挑战 | Peck, A. | N/A | Annotating CryoET Volumes: A Machine Learning Challenge | |
| 雌性蛾类将植物声学信号纳入其产卵决策中 | Seltzer, R. | N/A | Female Moths Incorporate Plant Acoustic Emissions into Their Oviposition Decision | |
| 利用CFD建模描述叶轮设计对植物细胞发酵的影响 | Manickavasagam, V. M. | N/A | Characterizing the effect of impeller design in plant cell fermentations using CFD modeling | |
| 磷酸酶PP2C12是LRX-RALF-FER介导的细胞壁完整性感知中的负调控因子。 | Hou, X. | N/A | The phosphatase PP2C12 is a negative player in LRX-RALF-FER-mediated cell wall integrity sensing | |
| 基质利用和交叉喂养协同作用决定了微生物群对病原体入侵的抵抗力 | Yang, X. | N/A | Substrate utilization and cross-feeding synergistically determine microbiome resistance to pathogen invasion | |
| 在脆性X模型中，重复扩展与由Pol θ、Rad52、Rad54l或Rad54b介导的双链断裂修复无关。 | Hayward, B. E. | N/A | Repeat expansion in a Fragile X model is independent of double strand break repair mediated by Pol θ, Rad52, Rad54l or Rad54b | |
| 细胞生长的几何平衡模型 | Vazquez, A. | N/A | Geometrically balanced model of cell growth | |
| 神经血管完整性与衰老中液体运输的关系：一项多模态神经影像学研究 | Rowsthorn, E. | N/A | Relationships between measures of neurovascular integrity and fluid transport in aging: a multi-modal neuroimaging study | |
| 皮层生长抑素中间神经元对神经血管耦合的双向调控 | Mohamed, B. | N/A | Bidirectional control of neurovascular coupling by cortical somatostatin interneurons | |
| 同时诱发的慢伽马波和快伽马波在灵长类动物初级视觉皮层中独立传播 | Gautham, B. K. | N/A | Simultaneously induced slow and fast gamma waves travel independently in primate primary visual cortex | |
| AAV载体中微RNA靶序列排列的优化显著增强了皮层小胶质细胞中转基因表达的特异性和效率 | Aoki, R. | N/A | Optimization of microRNA Target Sequence Arrangement in AAV Vectors Dramatically Enhances Specificity and Efficiency of Transgene Expression in Cortical Microglia | |
| RAB GTP酶的邻近图谱 | Gaudreault St-Laurent, V. | N/A | A Proximity MAP of RAB GTPases | |
| 一种用于蓝钟虫单细胞习惯化的受体失活模型 | Rajan, D. H. | N/A | A receptor-inactivation model for single-celled habituation in Stentor coeruleus | |
| ANKZF1通过LC3介导的线粒体自噬帮助消除应激损伤的线粒体。 | Ali, M. | N/A | ANKZF1 helps to eliminate the stress-damaged mitochondria by LC3-mediated mitophagy | |
| AMP激活蛋白激酶对网格蛋白介导的内吞作用的货物选择性调节 | Orofiamma, L. A. | N/A | Cargo-selective regulation of clathrin-mediated endocytosis by AMP-activated protein kinase | |
| 一种用于钙的绿色终身生物传感器，其亮度在其整个动态范围内保持稳定 | van der Linden, F. H. | N/A | A green lifetime biosensor for calcium that remains bright over its full dynamic range | |
| CDR2是一种动力蛋白适配器，被kinectin招募来调节内质网片的组织结构。 | Teixeira, V. | N/A | CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization | |
| 使用spoon处理空间分辨转录组数据中的均值-方差关系 | Shah, K. H. | N/A | Addressing the mean-variance relationship in spatially resolved transcriptomics data with spoon | |
| 光依赖的黄素氧化还原和加合物状态调控转录因子EL222的构象和DNA结合活性 | Chaudhari, A. S. | N/A | Light-dependent flavin redox and adduct states control the conformation and DNA binding activity of the transcription factor EL222 | |
| 利用带正电荷的可生物降解纳米材料实现体外和体内的mRNA高效递送 | Yang, X. | N/A | Efficient mRNA Delivery In Vitro and In Vivo Using a Polycharged Biodegradable Nanomaterial | |
| 通过免疫信息学和计算表位预测设计Mpox疫苗 | Rivera-Orellana, S. | N/A | Mpox Vaccine Design Through Immunoinformatics and Computational Epitope Prediction | |
| VirNA：一种用于研究病毒演化的新型最小生成网络算法 | Mazzotti, G. | N/A | VirNA: a novel Minimum Spanning Networks algorithm for investigating viral evolution | |
| 新冠病毒疾病（COVID）后疲劳持续超过12周与基于努力的决策过程中奖励敏感性降低相关。 | Scholing, J. M. | N/A | Fatigue >12 weeks after coronavirus disease (COVID) is associated with reduced reward sensitivity during effort-based decision making | |
| 综合宏基因组学和代谢组学揭示了实验性COVID-19中与年龄相关的肠道微生物群和代谢物改变 | Rodrigues, P. B. | N/A | Integrative metagenomics and metabolomics reveal age-associated gut microbiota and metabolite alterations in experimental COVID-19 | |
| 纳米颗粒支持的快速数字化量化针对SARS-CoV-2变种的中和抗体 | Mirjalili, S. | N/A | Nanoparticle-Supported, Rapid, Digital Quantification of Neutralizing Antibodies Against SARS-CoV-2 Variants | |
| BNT162b2 JN.1和KP.2适应型COVID-19疫苗的免疫学和生物物理特性 | Chen, W. | N/A | Immunologic and Biophysical Features of the BNT162b2 JN.1- and KP.2-Adapted COVID-19 Vaccines | |
| 利用铜绿假单胞菌荧光绿脓菌素色素开发发光塑料砖 | Pandey, K. | N/A | Development of glowing plastic bricks from waste plastic and florescent pyoverdine pigment of Pseudomonas aeruginosa | |
| 抗非生长和胞内细菌的抗菌化合物 | Kaldalu, N. | N/A | Antibacterial Compounds Against Non-Growing and Intracellular Bacteria | |
| 一个可访问的3D HepG2/C3A肝球体模型，支持恶性疟原虫在肝细胞内的完整生命周期 | Alqurashi, S. O. | N/A | An Accessible 3D HepG2/C3A Liver Spheroid Model Supporting the Complete Intrahepatocytic Lifecycle of Plasmodium falciparum | |
| 微生物学与人类学：在澳大利亚新南威尔士州农村冬季估计死亡时间的多学科方法。 | Green, H. | N/A | Microbiology and Anthropology: a multidisciplinary approach for estimating time since death during Winter in rural New South Wales, Australia. | |
| Lrp1促进Jamestown Canyon病毒对神经元的感染 | Frey, Z. D. | N/A | Lrp1 facilitates infection of neurons by Jamestown Canyon virus | |
| 牛瘤胃中大肠杆菌O26:H11、O111:H8和O145:NM血清型的生长动力学及蛋白质表达。 | Kudva, I. T. | N/A | Growth dynamics and protein-expression of Escherichia coli serotypes O26:H11, O111:H8 and O145:NM in the bovine rumen. | |
| 增强的胞外基质生成对无细胞壁的大肠杆菌提供了保护作用。 | Crooijmans, M. E. | N/A | Enhanced extracellular matrix production provides protection to cell wall-deficient Escherichia coli | |
| 与侵染红松的树皮甲虫相关的长喙壳科真菌，包括在中国发现的新种Ceratocystiopsis fushunensis的描述。 | Ran, Y. | N/A | Ophiostomatalean fungi associated with bark beetles infesting Pinus koraiensis, including the description of Ceratocystiopsis fushunensis sp. nov. in China | |
| 病毒样博格古菌染色体外元素与巨型真核病毒的趋同进化 | Banfield, J. | N/A | Convergent evolution of viral-like Borg archaeal extrachromosomal elements and giant eukaryotic viruses | |
| 通过一种创新的喷枪技术，证明了海洋环境相对于陆地环境缺乏功能性聚酯生物降解潜力。 | Contreras-Moll, A. | N/A | Lack of functional polyester-biodegrading potential in marine versus terrestrial environments evidenced by an innovative airbrushing technique | |
| 细菌和真菌中的木质纤维素降解用于生物质转化 | Hsin, K.-T. | N/A | Lignocellulose Degradation in Bacteria and Fungi for Biomass Conversion | |
| 通过元蛋白质组学评估水生关键物种在不同饮食下的关键肠道微生物组分和功能 | Dumas, T. | N/A | Key gut microbiota components and functions in an aquatic keystone species across diets assessed by metaproteomics | |
| SCA2/ALS13小鼠模型脊髓磷酸蛋白质组揭示了ATXN2-N端SH3-肌动蛋白相互作用网络的改变，以及通过WNK1-MYO6-OPTN-SQSTM1途径的自噬调控异常 | Almaguer-Mederos, L. E. | N/A | Spinal cord phosphoproteome of a SCA2/ALS13 mouse model reveals alteration of ATXN2-N-term SH3-actin interactome and of autophagy via WNK1-MYO6-OPTN-SQSTM1 | |
| MRAP2辅助蛋白直接与黑皮质素-3受体相互作用，以增强信号传导。 | Jamaluddin, A. | N/A | The MRAP2 accessory protein directly interacts with melanocortin-3 receptor to enhance signaling | |
| 通过细胞间mRNA转移在体外互补人类疾病表型 | Haimovich, G. | N/A | Complementation of a human disease phenotype in vitro by intercellular mRNA transfer | |
| 心脏重编程中的核小体重塑 | Harris, S. | N/A | Nucleosome repositioning in cardiac reprogramming | |
| 人类及其他大猿类端粒到端粒基因组中G-四链体的进化动力学 | Mohanty, S. K. | N/A | Evolutionary Dynamics of G-Quadruplexes in Human and Other Great Ape Telomere-to-Telomere Genomes | |
| 操纵IKZF1的可变剪接在T细胞中引发不同的基因调控反应 | Pastor, L. | N/A | Manipulation of alternative splicing of IKZF1 elicits distinct gene regulatory responses in T cells | |
| 发现嵌合聚酮类家族作为癌症免疫原性化疗先导物 | Xue, D. | N/A | Discovery of A Chimeric Polyketide Family as Cancer Immunogenic Chemotherapeutic Leads | |
| 由跨膜结构域结构可塑性调控的线粒体PINK1的替代进口通道和目的地 | Lorriman, J. | N/A | Alternative Import-Channels And Destinations Of Mitochondrial PINK1 Controlled By Trans-Membrane-Domain Structural Plasticity | |
| 在驯养条件下，野生肠道微生物群抑制了斑马鱼体内的机会性病原菌——气单胞菌。 | Kawano, K. | N/A | Wild gut microbiome suppresses the opportunistic pathogen Aeromonas in medaka under domesticated rearing conditions | |
| 保守的HIV-1间隔肽2触发基质晶格成熟 | Stacey, J. C. V. | N/A | The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation | |
| 长链非编码RNA HSCHARME通过调控在人类心肌病中改变的基因调控网络，促进干细胞衍生心肌细胞的成熟。 | Buonaiuto, G. | N/A | Long noncoding RNA HSCHARME promotes the maturation of stem cells-derived cardiomyocytes by controlling gene regulatory networks altered in human cardiomyopathies | |
| 与AMD相关的遗传多态性CFH Y402H使iPSC-RPE细胞对氢醌诱导的压力更为敏感。 | Armento, A. | N/A | The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells | |
| 通过在Cas9介导的基因组编辑过程中短暂双重抑制TP53和DNA甲基化，高效重新激活女性hPSC中的XIST。 | Motosugi, N. | N/A | Highly efficient XIST reactivation in female hPSC by transient dual inhibition of TP53 and DNA methylation during Cas9 mediated genome editing | |
| 在PYK2-null小鼠中，内皮细胞中可诱导的FAK缺失而非FAK抑制激活了p53，从而抑制肿瘤生长。 | Chen, X. L. | N/A | Inducible FAK Deletion but not FAK Inhibition in Endothelial Cells Activates p53 to Suppress Tumor Growth in PYK2-null Mice | |
| 全息显微镜揭示了在血管内皮化过程中，无需标记的内皮细胞定量动力学。 | Leineweber, W. D. | N/A | Holotomographic microscopy reveals label-free quantitative dynamics of endothelial cells during endothelialization | |
| 磷脂信号和多泡内溶酶体调节稻瘟菌共生界面处的膜动态变化 | Selvaraj, P. | N/A | Phospholipid signaling and multivesicular endolysosomes modulate membrane dynamics at the biotrophic interface in Rice Blast | |
| RING1 决定 GSDMD 介导的炎症反应及宿主对病原体感染的易感性 | Li, Y. | N/A | RING1 dictates GSDMD-mediated inflammatory response and host susceptibility to pathogen infection | |
| 鸡和鼠神经嵴发育的比较分析 | Kulesa, P. M. | N/A | Comparative Analysis of Neural Crest Development in the Chick and Mouse | |
| Wnt1-Cre2转基因会导致非神经嵴细胞类型的异常重组。 | Gandhi, S. | N/A | The Wnt1-Cre2 transgene causes aberrant recombination in non-neural crest cell types | |
| 体外受精引发雄性小鼠后代的生殖变化，并具有多代效应。 | Rhon-Calderon, E. A. | N/A | In Vitro Fertilization induces reproductive changes in male mouse offspring and has multigenerational effects | |
| EEMtoolbox：一个用户友好的R包，用于灵活的集成生态系统建模 | Pascal, L. V. | N/A | EEMtoolbox: A user-friendly R package for flexible ensemble ecosystem modeling | |
| 轻踏海底：延绳钓陷阱和钓钩渔具的海底接触定量估算 | Doherty, B. | N/A | Treading lightly: Quantitative estimates of seafloor contact for longline trap and hook fishing gear | |
| 自上而下的气候过程调节北美森林中的生物多样性与功能关系 | Maluquer, X. S. | N/A | TOP-DOWN CLIMATIC PROCESSES MODULATE BIODIVERSITY-FUNCTIONING RELATIONSHIPS ACROSS NORTH AMERICAN FORESTS | |
| 鱼类研究的边界？伊塔蒂亚亚探险与生物多样性数据库揭示了巴西高海拔水生生态系统中鱼类分布的空白 | Soares Guedes, G. H. | N/A | A fish frontier? Itatiaia expedition and biodiversity repositories reveal gaps in fish occurrences in Brazil's high-altitude aquatic ecosystems | |
| 湿度和竞争限制了埋葬甲繁殖的短暂资源质量 | Hayes, T. E. | N/A | Moisture and competition constrain ephemeral resource quality for burying beetle reproduction | |
| 电鳐科（Narcinidae，Gill, 1862）电鳐的谱系地理学：系统回顾与美洲扩散路径的证据。 | Rodrigues-Filho, L. F. S. | N/A | Phylogeography of the electric rays of the family Narcinidae (Gill, 1862): systematic review and evidence of the dispersal routes to America. | |
| 啤酒花中X-A平衡性决定系统的进化与功能 | Akagi, T. | N/A | Evolution and functioning of an X-A balance sex determination system in hops | |
| 由自由基和类过氧桥相互作用驱动的TCA循环中的C-C键断裂与生成 | Yang, L. | N/A | C-C bond cleavage and generation in TCA cycle driven by radicals and peroxo-bridge like interaction | |
| 开发新型可切割交联剂试剂用于细胞内交联的探索之旅 | Mueller, F. | N/A | A journey towards developing a new cleavable crosslinker reagent for in-cell crosslinking | |
| AistSeq：一种基于Tn5的内部质粒测序平台，采用紧凑型台式测序仪 | Suzuki, H. | N/A | AistSeq: An In-House Tn5-Based Plasmid Sequencing Platform Using A Compact Benchtop Sequencer | |
| 利用3D nnUnet和光片显微镜进行自动细胞追踪，以量化斑马鱼中的区域变形 | Teranikar, T. A. | N/A | Automated cell tracking using 3D nnUnet and Light Sheet Microscopy to quantify regional deformation in zebrafish | |
| 血小板膜包覆的超顺磁性氧化铁纳米粒子用于癌症治疗中的靶向紫杉醇递送和磁热疗 | Tavakoli, M. | N/A | Platelet Membrane-Coated SPION for Targeted Paclitaxel Delivery and Magnetic Hyperthermia in Cancer Therapy | |
| 金属离子对DNA纳米结构等温自组装的影响 | Rodriguez, A. | N/A | Influence of metal ions on the isothermal self-assembly of DNA nanostructures | |
| SingleFrag：一种用于MS/MS片段和光谱预测及代谢物注释的深度学习工具 | Perez-Ribera, M. | N/A | SingleFrag: A deep learning tool for MS/MS fragment and spectral prediction and metabolite annotation | |
| 多阶张量的统一分析用于综合分子特征分析 | De Azevedo, K. | N/A | Unified Analysis of Multi-order Tensors for Integrative Molecular Profiling | |
| 通过剪接进化的视角增强转录组注释 | Zang, X. C. | N/A | Augmenting Transcriptome Annotations through the Lens of Splicing Evolution | |
| Rthoptera：R语言中的标准化昆虫生物声学分析工具 | Rivas, F. | N/A | Rthoptera: standardized insect bioacoustics in R | |
| 胡萝卜中的植物化学物质对三阴性乳腺癌PDK1和PLK1具有治疗潜力。 | Raheem, k. | N/A | Phytochemicals from Daucus carota have therapeutic potential against Triple-Negative Breast Cancer PDK1 and PLK1. | |
| TomoPicker：冷冻电子断层扫描中的注释高效粒子挑选 | Uddin, M. R. | N/A | TomoPicker: Annotation-Efficient Particle Picking in cryo-electron Tomograms | |
| G4-Attention：用于预测DNA G-四链体的带注意力机制的深度学习模型 | Mukherjee, S. | N/A | G4-Attention: Deep Learning Model with Attention for predicting DNA G-Quadruplexes | |
| 阶段特异性基因比率突显了与无症状和有症状多发性骨髓瘤相关的基因和机制。 | Georgiou, G. | N/A | Stage-specific gene ratios highlight genes and mechanisms related to presymptomatic and symptomatic Multiple Myeloma | |
| 单细胞分辨率下的转录组装配与海狸 | Shi, Q. | N/A | Transcriptome Assembly at Single-Cell Resolution with Beaver | |
| PAIRWISE：基于深度学习的癌症个性化药物组合有效性预测 | Xu, C. | N/A | PAIRWISE: Deep Learning-based Prediction of Effective Personalized Drug Combinations in Cancer | |
| Biosynth Pipeline：一个集成平台，用于将嵌合型I类聚酮合酶的计算设计与化学生物合成的酶促途径相结合 | Chainani, Y. | N/A | Biosynth Pipeline: An integrated platform for merging the computational design of chimeric type I polyketide synthases with enzymatic pathways for chemical biosynthesis | |
| 单细胞转录组学揭示非酒精性脂肪肝疾病的基因组指标 | Thakur, M. | N/A | Single Cell Transcriptomics Reveal Genomic Indicators of Nonalcoholic Fatty Liver Disease | |
| 用于冷冻电镜图像处理的全面基础模型 | Yan, Y. | N/A | A comprehensive foundation model for cryo-EM image processing | |
| mcBERT：患者级单细胞转录组数据表示 | Querfurth, B. v. | N/A | mcBERT: Patient-Level Single-cell Transcriptomics Data Representation | |
| 单细胞数据自监督学习的基准测试 | Toma, P. | N/A | Benchmarking Self-Supervised Learning for Single-Cell Data | |
| 使用随机丙氨酸序列扫描结合AlphaFold2中的浅层子采样评估无配体和有配体蛋白质状态的结构与构象集合：对功能别构构象预测的见解与教训 | Raisinghani, N. | N/A | Assessing Structures and Conformational Ensembles of Apo and Holo Protein States Using Randomized Alanine Sequence Scanning Combined with Shallow Subsampling in AlphaFold2 : Insights and Lessons from Predictions of Functional Allosteric Conformations | |
| 微管动态由聚类原丝的构象和稳定性所决定。 | Kalutskii, M. | N/A | Microtubule dynamics are defined by conformations and stability of clustered protofilaments | |
| 酸性条件促进癌细胞来源的细胞外囊泡聚集，并增强其与合成脂质体的融合 | Fisher, W. S. | N/A | Acidic Conditions Promote Clustering of Cancer Cell Derived Extracellular Vesicles and Enhance their Fusion with Synthetic Liposomes | |
| DNA序列对ZTA转录因子-DNA复合物的热力学和结构稳定性的影响：一项全原子分子动力学研究 | Duraisamy, B. | N/A | Influence of DNA sequences on thermodynamic and structural stability of ZTA transcription factor - DNA complex: An all-atom molecular dynamics study | |
| 肌动蛋白周转和肌球蛋白收缩力决定了模拟细胞皮层的突现厚度鲁棒性 | Gat, S. | N/A | Actin turnover and myosin contractility determine emergent Thickness Robustness of Cell-Mimicking Cortex | |
| 蛋白质动力学构成了热感受器对温度强烈依赖的基础 | Qin, F. | N/A | Protein Dynamics Underlies Strong Temperature Dependence of Heat Receptors | |
| Tau-微管蛋白共凝聚物在早期微管组织中的结构化作用 | Lee-Eom, C. | N/A | Structuring Role of Tau-Tubulin Co-Condensates in Early Microtubule Organization | |
| 神经肽Y在水溶液中的pH依赖性结构动态变化 | Nguyen, T. H. | N/A | pH-dependent structural dynamics of the neuropeptide Y in aqueous solution | |
| 等离子体膜囊泡和磷脂酰胆碱-胆固醇囊泡的形状揭示了它们的有效自发曲率 | Kaur, H. | N/A | Shapes of Plasma Membrane Vesicles and PC-Cholesterol Vesicles Reveal Their Effective Spontaneous Curvature | |
| RNA梯度可以引导凝聚物向启动子区域移动：这对增强子-启动子接触以及凝聚物-启动子亲吻现象具有重要意义。 | Goh, D. | N/A | RNA gradients can guide condensates toward promoters: implications for enhancer-promoter contacts and condensate-promoter kissing | |
| 支气管镜诱导的转基因肺癌猪模型的人类可转化性特征 | Joshi, K. | N/A | Characterization of A Bronchoscopically Induced Transgenic Lung Cancer Pig Model for Human Translatability | |
| 阻断SHP2可增强FGFR2抑制剂的作用，并克服FGFR2扩增型胃癌中的耐药性。 | Zhang, Y. | N/A | Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in FGFR2-amplified gastric cancer | |
| 癌症中N基因和T基因的动力学 | Perez, G. J. G. | N/A | Dynamics of N-genes and T-genes in cancer | |
| 通过SdFFF和UHF-DEP标准化方法对结直肠癌细胞的特征化和分离：转录组分析强调 | JEMFER, C. | N/A | Towards a standardised method for the characterisation and isolation of colorectal cancer stem cells by SdFFF and UHF-DEP: highlighted by transcriptomic analysis | |
| 腱生蛋白-C增强甲状腺癌中的Wnt信号传导 | Hartmann, H. A. | N/A | Tenascin-C potentiates Wnt signaling in thyroid cancer | |
| 氯吡硫磷诱导肺转移并调节三阴性乳腺癌模型中的癌症干细胞标志物 | Lasagna, M. | N/A | Chlorpyrifos induces lung metastases and modulation of cancer stem cell markers in triple negative breast cancer model | |
| MPS1抑制剂NTRC 0066-0在体外和体内对胶质母细胞瘤疗效之间的脱节 | de Gooijer, M. C. | N/A | Disconnect between in vitro and in vivo efficacy of the MPS1 inhibitor NTRC 0066-0 against glioblastoma | |
| 血小板特异性P2Y1受体缺陷小鼠对脂多糖的反应中白细胞募集受到抑制。 | Pan, D. | N/A | Platelet-specific P2Y1 receptor deficient mice have suppressed leukocyte recruitment in response to lipopolysaccharide. | |
| Septins通过调节心肌细胞的储存操作钙内流来调控心脏收缩力。 | Tripoli, B. A. | N/A | Septins regulate heart contractility through modulation of cardiomyocyte store-operated calcium entry | |
| 循环小鼠来源的外泌体调节围绝经期小鼠肝脏转录组，与年龄无关 | Zanini, B. | N/A | EXOSOMES FROM CYCLIC MICE MODULATE LIVER TRANSCRIPTOME IN ESTROUPAUSE MICE INDEPENDENT OF AGE | |
| 利用基于集成网络的系统生物学方法预测与水稻（Oryza sativa）种子发育相关的新候选蛋白质，并分析其子模块和蛋白质枢纽。 | De Silva, M. R. P. | N/A | Prediction of new candidate proteins and analysis of sub-modules and protein hubs associated with seed development in rice (Oryza sativa) using an ensemble network-based systems biology approach. | |
| 发现和利用主动感知模式以实现基于经验可观测性的估计 | Cellini, B. | N/A | Discovering and exploiting active sensing motifs forestimation with empirical observability | |
| 高效有限差分法估计随机离散生化系统的二阶参数敏感性 | Jabeen, F. | N/A | Efficient Finite-Difference Estimation of Second-Order Parametric Sensitivities for Stochastic Discrete Biochemical Systems | |
| 一项针对心力衰竭的跨研究转录患者图谱揭示了心脏重塑过程中保守的多细胞协调机制。 | Lanzer, J. D. | N/A | A cross-study transcriptional patient map of heart failure defines conserved multicellular coordination in cardiac remodeling | |
| 常见的长足海绵属海绵花园：东北太平洋长足海绵科的分类修订揭示了许多隐秘的引入物种 | Turner, T. L. | N/A | A common garden of Halichondria sponges: taxonomic revision of Northeast Pacific Halichondriidae reveals many cryptic introduced species | |
| 血红素氧合酶-1对干扰素刺激基因表达的影响 | Chudy, P. | N/A | Effect of heme oxygenase-1 on the expression of interferon-stimulated genes | |
| 使用PANDORA进行MHC II类分子的双向肽构象预测 | Rademaker, D. T. | N/A | Bidirectional Peptide Conformation Prediction for MHC Class II using PANDORA | |
| TRPV4介导的机械转导调控瓣膜间质细胞向肌成纤维细胞的分化：对主动脉瓣狭窄的启示 | Mukherjee, P. | N/A | TRPV4-mediated Mechanotransduction Regulates the Differentiation of Valvular Interstitial Cells to Myofibroblasts: Implications for Aortic Stenosis | |
| Aramchol 减轻了胆道纤维化小鼠模型中的纤维化，并阻断了 TGFβ 诱导的胆管细胞中的纤维炎症介质。 | Aseem, S. O. | N/A | Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes | |
| Miro1表达改变全局基因表达、ERK1/2磷酸化、氧化应激以及细胞周期进程 | Shannon, N. | N/A | Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation, and cell cycle progression | |
| HumanTestisDB：睾丸转录组学和细胞相互作用的综合图谱 | Wang, M. | N/A | HumanTestisDB: A Comprehensive Atlas of Testicular Transcriptomics and Cellular Interactions | |
| 衰老对小鼠骨折后免疫和骨膜反应的影响 | King, J. S. | N/A | Effects of Aging on the Immune and Periosteal Response to Fracture in Mice | |
| 抑制DPP4活性通过支持脂肪酸和嘌呤代谢以及减轻炎症来保护由hiPSC衍生的脂肪性肝细胞（HLCs）。 | Loerch, C. | N/A | Inhibiting DPP4 activity protects hiPSC-derived steatotic HLCs by supporting fatty acid and purine metabolism and dampening inflammation | |
| L-乳酸通过MCT1运输、诱导代谢重编程和基因表达调控，诱导短期和长期的心脏保护作用。 | Cler, M. | N/A | L-lactic acid induces short- and long-term cardioprotective effects through MCT1 transport, induction of metabolic reprogramming, and gene expression modulation. | |
| CXXC5是一种泛素化蛋白，通过泛素化-蛋白酶体途径被降解。 | Ayten, H. | N/A | CXXC5 is a ubiquitinated protein and is degraded by the ubiquitination-proteasome pathway | |
| 新型小麦胚凝集素基质谱流式细胞术细胞条码标记试剂，适用于异质性、活体或固定样本 | Hannan, R. T. | N/A | Novel wheat germ agglutinin-based mass cytometry cell barcoding reagent for heterogeneous, live or fixed sample | |
| 口服暴露于PET微塑料会改变胰腺转录组——这对1型糖尿病的发病机制具有重要意义 | Mierzejewski, K. | N/A | Oral exposure to PET microplastics alters the pancreatic transcriptome-implications for the pathogenesis of type 1 diabetes | |
| 不对称基因流动维持着丰富的分布中心 | Hancock, Z. B. | N/A | Asymmetric gene flow maintains an abundant range center | |
| 子宫接受性的标志早于胎盘哺乳动物出现 | Basanta, S. | N/A | Hallmarks of uterine receptivity predate placental mammals | |
| 玉米重组景观在驯化过程中发生了演变。 | Epstein, R. | N/A | The maize recombination landscape evolved during domestication. | |
| 通过比较转录组学深入了解四足动物双锥体的进化起源 | Tommasini, D. | N/A | Comparative transcriptomic insights into the evolutionary origin of the tetrapod double cone | |
| 阿尔法细胞理论：模拟生命系统中的自组装和动态过程 | Gruhlke, M. C. H. | N/A | Alpha Cell Theory: Modeling Self-Assembly and Dynamic Processes in Living Systems | |
| 氨基酸性质、替代速率以及近中性理论 | James, J. | N/A | Amino acid properties, substitution rates, and the nearly neutral theory | |
| 范围扩张的历史生物地理学预测了繁殖保障的空间模式 | Urquhart-Cronish, M. | N/A | The historical biogeography of range expansion predicts spatial patterns in reproductive assurance | |
| 磁性细菌在天然孔隙网络中实现最佳导航 | Petroff, A. P. | N/A | Magnetotactic Bacteria Optimally Navigate Natural Pore Networks | |
| 细菌生命树中利福平抗性的进化与可进化性 | Bolourchi, N. | N/A | Evolution and evolvability of rifampicin resistance across the bacterial tree of life | |
| 在免疫检查点阻断的背景下定义CD8+ T细胞受体库的遗传决定因素 | Ng, E. | N/A | Defining the genetic determinants of CD8+ T cell receptor repertoire in the context of immune checkpoint blockade | |
| 以单个氨基酸分辨率进行蛋白质测序可以识别出区分肌动蛋白原形态的肽段。 | Sittipongpittaya, N. | N/A | Protein sequencing with single amino acid resolution discerns peptides that discriminate tropomyosin proteoforms | |
| 长寿中的玛土撒拉蛋白：通过数学基因组学揭示其影响 | Hassan, S. S. | N/A | Methuselah Proteins in Longevity: Unraveling Their Impact Through Mathematical Genomics | |
| 去氨酶辅助的单分子和单细胞染色质纤维测序 | Swanson, E. G. | N/A | Deaminase-assisted single-molecule and single-cell chromatin fiber sequencing | |
| 新生转录本O-MAP揭示了由RBM20和TTN RNA构建的单基因位点亚核区室的分子结构 | Kania, E. E. | N/A | Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the TTN RNA | |
| # BioRxiv 2024-11-05 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| YAP通过Rho-GTPase开关控制细胞迁移和侵袭 | Shah, S. R. | N/A | YAP controls cell migration and invasion through a Rho-GTPase switch | |
| 益生菌治疗鼻腔金黄色葡萄球菌去定植的计算和体外评估 | Tepekule, B. | N/A | Computational and in vitro evaluation of probiotic treatments for nasal Staphylococcus aureus decolonization | |
| 转录组数据揭示了食蚁兽和穿山甲在饮食趋同背景下几丁质酶进化的不同路径 | Allio, R. | N/A | Transcriptomic data reveal divergent paths of chitinase evolution underlying dietary convergence in anteaters and pangolins | |
| 用于多重行为学和单细胞转录组学研究的确定性遗传条形码技术 | Mendana, J. B. | N/A | Deterministic Genetic Barcoding for Multiplexed Behavioral and Single-Cell Transcriptomic Studies | |
| 最长命哺乳动物中的DNA修复与抗癌机制：弓头鲸 | Firsanov, D. | N/A | DNA repair and anti-cancer mechanisms in the longest-living mammal: the bowhead whale | |
| 活性粒子诱导的网络范围张力波动对脂质泡沫原组织进行重塑 | Gu, A. A. | N/A | Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles | |
| 解码视觉空间注意力控制 | Meyyappan, S. | N/A | Decoding Visual Spatial Attention Control | |
| Tgfbr1 调控侧板中胚层和内胚层在躯干向尾部过渡期间的重组 | Lozovska, A. | N/A | Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition | |
| 厘米级组织和胚胎中大量异质细胞群体的体积跨尺度成像 | Ichimura, T. | N/A | Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo | |
| 免疫缺陷相关激活型PIK3R1变异的矛盾性显性负性活性 | Tomlinson, P. R. | N/A | Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant | |
| 脱轨细胞状态的联合表示与可视化：Decipher | Nazaret, A. | N/A | Joint representation and visualization of derailed cell states with Decipher | |
| 脑网络动态在不同情境下预测惊讶时刻 | Zhang, Z. | N/A | Brain network dynamics predict moments of surprise across contexts | |
| BRD4介导的内质网-线粒体接触位点的表观遗传调控受线粒体复合物III的调控。 | Chen, B. | N/A | BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III | |
| 在狨猴对中，性别和熟悉程度对社交凝视的动态调节 | Xing, F. | N/A | Dynamic modulation of social gaze by sex and familiarity in marmoset dyads | |
| CTCF锚定的染色质环在人类减数分裂期间的动力学 | Kaiser, V. B. | N/A | CTCF-anchored chromatin loop dynamics during human meiosis | |
| 从头检测高质量长读长单细胞RNA测序数据中的体细胞变异 | Dondi, A. | N/A | De novo detection of somatic variants in high-quality long-read single-cell RNA sequencing data | |
| 水熊虫Hypsibius exemplaris中通过qRT-PCR比较相对转录水平的单动物、单管RNA提取方法。 | Kirk, M. J. | N/A | Single-animal, single-tube RNA extraction for comparison of relative transcript levels via qRT-PCR in the tardigrade Hypsibius exemplaris. | |
| PIPETS：一种基于统计学原理、不依赖基因注释的分析方法，用于通过3'-端测序研究细菌终止机制。 | Furumo, Q. | N/A | PIPETS: A statistically informed, gene-annotation agnostic analysis method to study bacterial termination using 3'-end sequencing. | |
| moPepGen：快速全面鉴定非规范肽 | Zhu, C. | N/A | moPepGen: Rapid and Comprehensive Identification of Non-canonical Peptides | |
| 新胱氨酸摇篮家族中的一个典型成员是一种aECM蛋白，它在秀丽隐杆线虫中传递皮肤损伤的信号。 | Sonntag, T. | N/A | A defining member of the new cysteine-cradle family is an aECM protein signalling skin damage in C. elegans | |
| 优化系统发育特征向量回归中的变量选择以进行性状相关性分析 | Chen, Z.-L. | N/A | Optimizing Variable Selection in Phylogenetic Eigenvector Regression for Trait Correlation Analysis | |
| 斑马鱼作为研究PERK功能在发育性疾病中的作用的模式生物：对Wolcott-Rallison综合征的启示 | Almeida, L. M. | N/A | Zebrafish as a model to study PERK function in developmental diseases: implications for Wolcott-Rallison syndrome | |
| 解决SARS-CoV-2系统发育中的大流行性系统错误 | Hunt, M. | N/A | Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny | |
| 新型酵母共生体的设计及其在酿酒发酵生态研究中的应用 | Pourcelot, E. | N/A | Design of a new model yeast consortium for ecological studies of enological fermentation | |
| Ezrin通过EGFR-AKT信号通路在细胞内小泡区室中定义了TSC复合物的激活。 | Giamundo, G. | N/A | Ezrin defines TSC complex activation at endosomal compartments through EGFR-AKT signaling. | |
| 表皮胶原蛋白主动调节感觉神经元的衰老 | Krishna, M. | N/A | Epidermal Collagen Actively Regulates the Aging of Sensory Neurons | |
| 线性感知运动转换解释了人类航向估计中与反应范围相关的偏差 | Sun, Q. | N/A | A linear sensorimotor transformation accounts for response range-dependent biases in human heading estimation | |
| 消化和肠腔流动的昼夜变化决定了人类大肠微生物群落的动态变化。 | Salari, A. | N/A | Diurnal variations in digestion and luminal flow determine microbial population dynamics along the human large intestine | |
| 发条猩猩：微小RNA、体温调节权衡与脑容量进化。 | Fromm, B. | N/A | Clockwork Orangutan: microRNAs, thermoregulatory tradeoffs, and the evolution of brain size. | |
| RNA会根据需要调整其灵活性，以便高效折叠并抵抗展开。 | Jang, S. S. | N/A | RNA adapts its flexibility to efficiently fold and resist unfolding | |
| 基于人工智能的新型药物-基因-疾病相互作用识别方法，利用蛋白质-蛋白质相互作用 | Taguchi, Y.-h. | N/A | Novel artificial intelligence-based identification of drug-gene-disease interaction using protein-protein interaction | |
| 片段化DNA的“深度采样”PCR揭示了克氏锥虫在慢性感染宿主中的广泛负担范围，并允许在治疗后对寄生虫负荷进行准确监测。 | White, B. E. | N/A | Serial "deep-sampling" PCR of fragmented DNA reveals the wide range of Trypanosoma cruzi burden among chronically infected hosts and allows accurate monitoring of parasite load following treatment | |
| 与淀粉样变性、溶酶体不稳定和出血相关的病理性轴突增大是阿尔茨海默病中的主要缺陷。 | Fu, H. | N/A | Pathological axonal enlargement in connection with amyloidosis, lysosome destabilization and hemorrhage is a major defect in Alzheimer's disease | |
| 在热带森林实验中，树木多样性增加了地上的碳储存和通量，但对地下的碳储存和通量没有影响。 | Schnabel, F. | N/A | Tree diversity increases carbon stocks and fluxes above- but not belowground in a tropical forest experiment | |
| 通过细胞类型动态系统解析不同细胞类群的作用 | Jha, A. | N/A | Disentangling the Roles of Distinct Cell Classes with Cell-Type Dynamical Systems | |
| 人类微生物组的综合生物合成分析揭示了多样化的保护性核糖体肽 | ZHANG, J. | N/A | Comprehensive Biosynthetic Analysis of Human Microbiome Reveals Diverse Protective Ribosomal Peptides | |
| 在猕猴视觉注意过程中小脑齿状核神经元活动的编码 | Flierman, N. A. | N/A | Encoding of cerebellar dentate neuronal activity during visual attention in rhesus macaques | |
| 个体间声道的多样性影响口语语言的语音多样化 | Moran, S. | N/A | Interindividual vocal tract diversity influences the phonetic diversification of spoken languages | |
| 机器学习揭示关键糖蛋白突变并快速划分拉沙病毒谱系 | Daodu, R. O. | N/A | Machine Learning Reveals Key Glycoprotein Mutations and Rapidly Assigns Lassa Virus Lineages | |
| 极性建立和中心体纺锤体独立性细胞分裂的最小数学模型 | Maxian, O. | N/A | A minimal mathematical model for polarity establishment and centralspindlin-independent cytokinesis | |
| 通过单胺能核团内固有调制对功能上不同的输入进行多路复用，以调节放电时序 | Lynn, M. B. | N/A | Multiplexing of functionally distinct inputs by intrinsic modulation of spike timing in a monoaminergic nucleus | |
| 消除常见的神经选择信号并不会使它们成为人工产物。对Frömer等人（2024年，《自然·人类行为》）的评论。 | O'Connell, R. G. | N/A | Regressing Away Common Neural Choice Signals does not make them Artifacts. Comment on Frömer et al (2024, Nature Human Behaviour) | |
| 气候变化与病原体多样性之间的相互作用塑造了农业环境中地方性疾病的动力学 | Bhandari, R. | N/A | Interaction between climatic variation and pathogen diversity shape endemic disease dynamics in the agricultural settings | |
| 空间转录组学的基因表达框架 | Cao, S. | N/A | A gene representation framework for spatial transcriptomics | |
| 体内T细胞共调节因子B7-H4的成像揭示了前列腺癌中的促肿瘤巨噬细胞状态 | Kumar, M. | N/A | In vivo imaging of T-cell coregulator B7-H4 reveals protumor macrophage status in prostate cancer | |
| 一种综合的蛋白质组学和转录组学方法揭示了新的ADAM9底物及其下游通路 | Lu, C. | N/A | An integrative proteotranscriptomics approach reveals new ADAM9 substrates and downstream pathways | |
| 模块化噬菌体T4纳米颗粒平台助力快速设计双效COVID-19-流感黏膜疫苗 | Zhu, J. | N/A | A Modular Bacteriophage T4 Nanoparticle Platform Enables Rapid Design of Dual COVID-19-Flu Mucosal Vaccines | |
| 代谢微调与心脏细胞因子分泌是果蝇对高脂肪和高糖饮食的适应性反应。 | Khamvongsa-Charbonnier, L. | N/A | Metabolism fine tuning and cardiokines secretion represent adaptative responses of the heart to High Fat and High Sugar Diets in flies | |
| 食物摄入增强了海马体的锋电位波纹复合体。 | Kaya, E. | N/A | Food intake enhances hippocampal sharp wave-ripples | |
| EphA2 和磷酸抗原介导的 γδT 细胞对髓母细胞瘤的选择性杀伤保护了神经元和干细胞的完整性 | Boutin, L. | N/A | EphA2 and Phosphoantigen-Mediated Selective Killing of Medulloblastoma by γδT Cells Preserves Neuronal and Stem Cell Integrity | |
| β-肾上腺素能阻滞剂通过胰腺β细胞中的PKA/RYR2/TRPM5途径增加cAMP并刺激胰岛素分泌，此过程在体外实验中得到验证。 | Murao, N. | N/A | β-adrenergic blockers increase cAMP and stimulate insulin secretion through a PKA/RYR2/TRPM5 pathway in pancreatic β-cells in vitro | |
| 发现广谱细菌多胺解毒抑制剂作为潜在的抗毒力剂和抗生素佐剂 | Moulding, P. B. | N/A | Discovery of broad-spectrum bacterial polyamine detoxification inhibitors as potential antivirulence agents and antibiotic adjuvants | |
| 人类在空间导航过程中前额叶Theta波和顶叶Alpha波振荡事件的单次试验特征 | Cuello, M. T. | N/A | Single trial characterization of frontal Theta and parietal Alpha oscillatory episodes during Spatial Navigation in humans | |
| 经典的统计方法在识别乳腺癌患者生存的新靶点方面具有强大的作用。 | Insawang, B. | N/A | Classical statistical methods are powerful for the identification of novel targets for the survival of breast cancer patients | |
| 利用智能手机RGB图像和LiDAR点云进行增强的叶片氮素和地上生物量评估——以中国菠菜为案例研究 | Harikumar, A. | N/A | Harnessing Smartphone RGB Imagery and LiDAR Point Cloud for Enhanced Leaf Nitrogen and Shoot Biomass Assessment - Chinese Spinach as a Case Study | |
| 比较时空单细胞转录组揭示了C4草类Kranz解剖结构出现过程中预存调控的重塑 | Zhao, C. | N/A | Comparative spatiotemporal single cell transcriptomes reveal rewiring of pre-existing regulations during emergence of Kranz anatomy in C4 grasses | |
| 一种组合域筛选平台揭示了表观遗传效应因子与转录扰动之间的相互作用 | Moon, H. C. | N/A | A combinatorial domain screening platform reveals epigenetic effector interactions for transcriptional perturbation | |
| 有机和无机污染物及其混合物对发育期暴露斑马鱼代谢健康和基因表达的影响 | Berube, R. | N/A | Effects of organic and inorganic contaminants and their mixtures on metabolic health and gene expression in developmentally exposed zebrafish | |
| 利用多环境试验育种数据优化基因型特异性参数评估木薯作物生长模型 | Okoma, P. M. | N/A | Evaluating a Cassava Crop Growth Model by Optimizing Genotypic-Specific Parameters Using Multi-environment Trial Breeding Data | |
| C3-C3aR轴调控肺泡巨噬细胞的训练免疫 | Earhart, A. P. | N/A | The C3-C3aR axis modulates trained immunity in alveolar macrophages | |
| Squeakuences：一种便携式工具，用于格式化无瑕疵的序列，以消除生物信息学软件的不兼容性 | Lane, L. E. | N/A | Squeakuences: a portable tool for formatting squeaky-clean sequences to eliminate bioinformatic software incompatibilities | |
| 探索恶性疟原虫二氢叶酸还原酶的适应性景观：抗叶酸耐药性的进化见解 | Muzata, D. | N/A | Navigating the Fitness Landscapes of Plasmodium falciparum Dihydrofolate Reductase: Evolutionary Insights into Antifolate Resistance | |
| 一种全球性的多巴胺能学习率能够使适应性觅食在众多选择中进行。 | Grima, L. L. | N/A | A global dopaminergic learning rate enables adaptive foraging across many options | |
| 验证DXS作为分枝杆菌中具有吸引力的药物靶点 | Maila, T. | N/A | Validation of DXS as an attractive drug target in mycobacteria | |
| 神经溶酶体定位与功能的小分子调节剂可解决培养的人类神经元中与阿尔茨海默病相关的病理 | Snead, A. M. | N/A | Small molecule modulator of neuronal lysosome positioning and function resolves Alzheimers Disease-linked pathologies in cultured human neurons | |
| 小鼠新皮层深层6层兴奋性神经元的共识定义 | Kim, S.-J. | N/A | A consensus definition for deep layer 6 excitatory neurons in mouse neocortex | |
| 皮质纹状体投射招募黑质外侧部多巴胺能神经元用于听觉威胁记忆 | Sansalone, L. | N/A | Corticonigral projections recruit substantia nigra pars lateralis dopaminergic neurons for auditory threat memories | |
| 保守开花基因的顺式调控元件的拮抗作用介导了发育的稳健性。 | Lanctot, A. | N/A | Antagonizing cis-regulatory elements of a conserved flowering gene mediate developmental robustness | |
| 对蝾螈Y染色体转换的鉴定未能支持Triturus平衡致死系统起源于性染色体的观点 | France, J. M. | N/A | Identification of Y-chromosome turnover in newts fails to support a sex chromosome origin for the Triturus balanced lethal system | |
| xIV-LDDMM工具包：一套基于图像-变分技术的工具，用于在多尺度上同时表示和映射三维成像和空间组学数据 | Stouffer, K. | N/A | xIV-LDDMM Toolkit: A Suite of Image-Varifold Based Technologies for Representing and Mapping 3D Imaging and Spatial-omics Data Simultaneously Across Scales | |
| 一种高山植物在冰川后迅速扩张的范围内没有表现出遗传多样性的下降。 | Urquhart-Cronish, M. | N/A | An alpine plant shows no decrease in genetic diversity associated with rapid post-glacial range expansion | |
| 丛枝菌根真菌中转座元件的分析支持其与植物病原真菌在进化上的相似性 | Oliveira, J. I. | N/A | Analyses of transposable elements in arbuscular mycorrhizal fungi support evolutionary parallels with fungal plant pathogens | |
| 对丛枝菌根真菌中转座子元素的分析支持其与丝状植物病原体在进化上的平行性。 | Oliveira, J. I. | N/A | Analyses of transposable elements in arbuscular mycorrhizal fungi support evolutionary parallels with filamentous plant pathogens | |
| SeedMatExplorer：拟南芥种子成熟转录组图谱 | Artur, M. A. S. | N/A | SeedMatExplorer: The transcriptome atlas of Arabidopsis seed maturation | |
| PII蛋白与BADC和BCCP蛋白的相互作用共同调控拟南芥中的脂质和氮代谢 | Garneau, M. G. | N/A | PII interactions with BADC and BCCP proteins co-regulate lipid and nitrogen metabolism in Arabidopsis | |
| 5-甲基胞嘧啶DNA糖基化酶ROS1对抗拟南芥胚乳中亲本特异性DNA甲基化 | Hemenway, E. A. | N/A | The 5-methylcytosine DNA glycosylase ROS1 antagonizes parent-of-origin specific DNA methylation in Arabidopsis endosperm | |
| 高温和微生物群落条件影响大豆基因表达 | Van der Laan, L. | N/A | High Temperature and Microbiome Conditions Affect Gene Expression in Soybean | |
| 红藻Galdieria sulphuraria NIES-3638中PSI-LHCI复合物的LHCI蛋白多样性的生化证据 | Nagao, R. | N/A | Biochemical evidence for the diversity of LHCI proteins in PSI-LHCI from the red alga Galdieria sulphuraria NIES-3638 | |
| 衰老促使植物器官中DNA甲基化衰减的程序启动 | Dai, D. | N/A | Aging drives a program of DNA methylation decay in plant organs | |
| PATROL1介导的H+-ATP酶转运通过优化根和叶的功能，在干旱条件下促进植物生长。 | Katsuhama, N. | N/A | PATROL1-mediated H+-ATPase translocation boosts plant growth under drought by optimizing root and leaf functions | |
| 番茄根系对细菌来源的肽表现出明显的、与发育阶段相关的反应 | Leuschen-Kohl, R. L. | N/A | Tomato roots exhibit distinct, development-specific responses to bacterial-derived peptides | |
| 压缩力通过ERK信号通路诱导衰老的人类真皮成纤维细胞的表观遗传激活 | Liu, H. | N/A | Compressive forces induce epigenetic activation of aged human dermal fibroblasts through ERK signalling pathway | |
| KLF7调控的ITGA2作为抑制口腔癌干细胞的治疗靶点 | QI, X. | N/A | KLF7-Regulated ITGA2 as a Therapeutic Target for Inhibiting Oral Cancer Stem Cells | |
| 靶向黑色素瘤细胞的能量代谢：FX-11作为线粒体解偶联剂 | Preis, J. R. | N/A | Targeting the energy metabolism of melanoma cells: FX-11 acts as a mitochondrial uncoupler | |
| 一种罕见的造血干细胞来源的巨核细胞祖细胞通过增强的存活而积累，并在衰老时促进血栓形成加剧 | Manso, B. A. | N/A | A rare HSC-derived megakaryocyte progenitor accumulates via enhanced survival and contributes to exacerbated thrombopoiesis upon aging | |
| 草酸铁钾纳米颗粒在小鼠模型中可预防人类血液凝固和血栓形成 | Yenurkar, D. | N/A | Potassium ferric oxalate nanoparticles prevent human blood clotting and thrombosis in a mouse model | |
| 基于EEG连接组的健康受试者非言语智力水平的预测建模 | Pashkov, A. A. | N/A | EEG connectome-based predictive modeling of nonverbal intelligence level in healthy subjects | |
| 通过Sac1依赖的PI(4)P和胆固醇的共同调控来控制高尔基体V-ATPase | Zhou, X. | N/A | Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol | |
| TFG环复合体在神经元货物运输中具有多种作用 | Zhang, Z. | N/A | Multiple roles for TFG ring complexes in neuronal cargo trafficking | |
| 微管锚定因子NEDD1与γ-微管蛋白环复合物结合的结构 | Munoz Hernandez, H. | N/A | Structure of the microtubule anchoring factor NEDD1 bound to the γ-tubulin ring complex | |
| 用于冷冻电镜断层成像颗粒挑选机器学习竞赛的开源工具 | Harrington, K. I. | N/A | Open-source Tools for CryoET Particle Picking Machine Learning Competitions | |
| 中和抗体对SARS-CoV-2 JN.1变种KP.3、KP.3.1.1、LB.1和XEC的逃逸 | Sano, K. | N/A | Neutralizing antibody evasion of SARS-CoV-2 JN.1 derivatives KP.3, KP.3.1.1, LB.1, and XEC | |
| 两种致病真菌中将单倍体染色体分配到不同细胞核的过程 | Li, X. | N/A | Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi | |
| 通过额外结合髓鞘少突胶质细胞糖蛋白（一种中枢神经系统特异性蛋白），延长抗体在大脑中的半衰期 | Cuypers, M.-L. | N/A | Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein | |
| 用于DNA数据存储中无PCR随机访问的纳米孔测序自适应采样 | Sokolovskii, R. | N/A | Adaptive sampling in nanopore sequencing for PCR-free random access in DNA data storage | |
| DNA-SaM是一种用于大规模数据存储的强大系统。 | Huang, X. | N/A | DNA-SaM, a robust system for large-scale data storage | |
| A群链球菌碳水化合物生物合成基因的自然变异影响宿主-病原体相互作用 | Tamminga, S. M. | N/A | Natural variation of the streptococcal Group A carbohydrate biosynthesis genes impacts host-pathogen interaction | |
| 粘附侵袭性大肠杆菌对环丙沙星的持久性表型，揭示了高持久性菌株 | Perez-Villalobos, V. | N/A | Persistence phenotype of adherent-invasive Escherichia coli in response to ciprofloxacin, revealing high-persistence strains | |
| 临床环境中大肠埃希菌菌株的自动监测 | Rodriguez Palomo, R. | N/A | Automatic surveillance of Escherichia coli bacteriological strains within clinical settings | |
| 单分子成像揭示了RNase E在埃希氏大肠杆菌中的定位和扩散过程中，膜结合基序和C端结构域的作用 | Troyer, L. | N/A | Single-molecule imaging reveals the role of membrane-binding motif and C-terminal domain of RNase E in its localization and diffusion in Escherichia coli | |
| 直接脂质相互作用调控SARS-CoV-2 M蛋白的构象动态变化及病毒组装 | Dutta, M. | N/A | Direct lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly | |
| 疟原虫无性复制和热耐受性的关键作用依赖于HSP40 | Roper, B. | N/A | Essential role for HSP40 in asexual replication and thermotolerance of malaria parasites | |
| PgtE蛋白酶使致病性沙门氏菌能够逃避C3介导的血清和嗜中性粒细胞杀伤作用。 | Lee, M. H. | N/A | PgtE protease enables virulent Salmonella to evade C3-mediated serum and neutrophil killing | |
| 大肠杆菌中的硫化物响应转录调控 | Hori, K. | N/A | Sulfide-responsive transcription control in Escherichia coli | |
| 23S rRNA螺旋69的远端核糖2'-O-甲基化预先确定了核糖体亚基界面处的缠霉素药物结合口袋 | Nandi, S. | N/A | Distant Ribose 2'-O-Methylation of 23S rRNA Helix 69 Pre-Orders the Capreomycin Drug Binding Pocket at the Ribosome Subunit Interface | |
| 铜绿假单胞菌必需基因扰动，使其在哺乳动物宿主环境中变得脆弱 | Prasad, N. K. | N/A | Pseudomonas aeruginosa essential gene perturbations that confer vulnerability to the mammalian host environment | |
| 慢性分枝杆菌感染会引发巨噬细胞衰老。 | Scarpa, E. | N/A | Chronic mycobacteria infection triggers macrophage senescence | |
| 原核生物抗病毒防御中利他主义的生态决定因素 | Biba, D. A. | N/A | Ecological Determinants of Altruism in Prokaryote Antivirus Defense | |
| 比较RT-qPCR和qPCR揭示了柑橘黄龙病菌（Candidatus Liberibacter asiaticus）的早期感染、低拷贝感染以及相对细胞活性。 | Patterson, R. | N/A | Comparative RT-qPCR and qPCR reveals early infection, low-titer infection, and relative cell activity of the HLB bacterium, Candidatus Liberibacter asiaticus | |
| 通过高速原子力显微镜直接观察亨廷顿蛋白淀粉样形成中的二次成核现象 | van Ewijk, C. | N/A | Direct observation of secondary nucleation in huntingtin amyloid formation by High-Speed Atomic Force Microscopy | |
| 在不同发育阶段，本地适应的内陆一年生和沿海多年生生态型之间的基因表达差异 | Olsen, J. D. | N/A | Gene expression divergence between locally adapted inland annual and coastal perennial ecotypes of Mimulus guttatus across developmental stages | |
| 改进的分裂质粒编辑器能够实现高效的体内基因编辑 | Wei, R. | N/A | Improved split prime editors enable efficient in vivo genome editing | |
| 鞭毛内运输蛋白IFT172含有一个C端泛素结合的U型盒样结构域，参与纤毛信号传导。 | Zacharia, N. K. | N/A | Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling | |
| Blm10的结构：13S蛋白酶体中间体揭示了蛋白酶体核心颗粒的并行组装途径 | Kaur, M. | N/A | Structure of Blm10:13S proteasome intermediate reveals parallel assembly pathways for the proteasome core particle | |
| 缺乏多接头区域外限制位点的酿酒酵母极简整合穿梭载体 | Scutteri, L. | N/A | Minimal integrating shuttle vectors for Saccharomyces cerevisiae depleted of restriction sites outside the polylinker region | |
| 谷氨酸棒杆菌系统代谢工程用于高效L-色氨酸生产 | Dong, Y. | N/A | Systems metabolic engineering of Corynebacterium glutamicum for efficient L-tryptophan production | |
| ITD对于（有偏差的）人类听觉方位感知是充分的 | Azevedo, A. C. P. F. O. d. | N/A | Sufficiency of ITD for (biased) human auditory azimuthal perception | |
| 腹侧苍白球-伏隔核壳核通路的化学遗传学操控可调节雌性大鼠的蔗糖摄入，且与动机无关。 | Peroutka, M. M. | N/A | Chemogenetic manipulation of the ventral pallidum-nucleus accumbens shell pathway modulates sucrose consumption independent of motivation in female rats. | |
| Contactin-1 是周围神经网络结构的关键神经细胞表面受体。 | Sinha, A. | N/A | Contactin-1 is a critical neuronal cell surface receptor for perineuronal net structure | |
| 特异性环状RNA circDS-1通过调控双态转变和毒力，促进塔罗霉菌（Talaromyces marneffei）的适应性进化 | Hu, X. | N/A | Species-specific circular RNA circDS-1 enhances adaptive evolution in Talaromyces marneffei through regulation of dimorphic transition and virulence | |
| 多组学单细胞分析揭示了HIV-1早期感染中持续存在和宿主免疫反应异常的关键调控因子 | Lee, D. | N/A | Multi-Omics Single-Cell Analysis Reveals Key Regulators of HIV-1 Persistence and Aberrant Host Immune Responses in Early Infection | |
| 金黄色葡萄球菌与铜绿假单胞菌之间的多微生物相互作用促进了生物膜的形成和在慢性伤口感染中的持久性。 | Keim, K. C. | N/A | Polymicrobial interactions between Staphylococcus aureus and Pseudomonas aeruginosa promote biofilm formation and persistence in chronic wound infections | |
| 一种模型，源自脊髓损伤患者的混合物种尿道导管生物膜 | Noorian, P. | N/A | A model, mixed-species urinary catheter biofilm derived from spinal cord injury patients | |
| 结构导向的突变分析揭示了小鼠胰岛素受体5'UTR IRES功能中一个关键的保守区域 | Dahl, W. B. | N/A | Structure-informed mutagenesis identifies a conserved region critical for mouse insulin receptor 5'UTR IRES function | |
| 来自曲霉的疏水蛋白介导真菌与微塑料的相互作用 | Klauer, R. R. | N/A | Hydrophobins from Aspergillus mediate fungal interactions with microplastics | |
| 大西洋鲑鱼对IPNV和ISAV病毒反应中宿主蛋白的不同泛素化 | Stewart, R. | N/A | Differential Ubiquitination of Host Proteins in Response to IPNV and ISAV viruses in Atlantic salmon | |
| 维生素B12通过改善丙酸分解和一碳循环代谢途径，部分挽救了秀丽隐杆线虫Ephrin突变体胚胎细胞迁移缺陷。 | Ganjawala, T. H. | N/A | Vitamin B12 partially rescues embryonic cell migration defects in C. elegans ephrin mutants by improving both propionic acid breakdown and one-carbon cycle metabolic pathways | |
| 气候和捕食压力驱动南非狒狒（Papio ursinus）昼夜活动模式的变异 | Dzingwena, L. | N/A | Climate and predation drive variation of diel activity patterns in chacma baboons (Papio ursinus) across southern Africa | |
| 非尿素选择性GIRK通道激活剂的低剂量改善了由淀粉样β寡聚体破坏的海马依赖性突触可塑性和记忆 | Mulero-Franco, J. | N/A | Low dose of a non-urea selective GIRK channel activator improves hippocampal-dependent synaptic plasticity and memory disrupted by amyloid-β oligomers | |
| 一种神经网络模型，能够在秀丽隐杆线虫中生成依赖于盐浓度记忆的趋化行为 | Hironaka, M. | N/A | A neural network model that generates salt concentration memory-dependent chemotaxis in Caenorhabditis elegans | |
| 选择和结果的神经编码受到眶额皮层中不确定性的调节，但在次级运动皮层中则不受此影响。 | Romero-Sosa, J. L. | N/A | Neural coding of choice and outcome are modulated by uncertainty in orbitofrontal but not secondary motor cortex | |
| 小胶质细胞通过胞外核苷酸酶CD39调节脑血流量和神经血管耦合 | Fu, Z. | N/A | Microglia modulate cerebral blood flow and neurovascular coupling through ectonucleotidase CD39 | |
| HA1（一种普罗布考类似物）和ApoC3 siRNA对db/db小鼠脂蛋白-淀粉样蛋白代谢、神经血管完整性及认知功能的影响 | Sharif, A. | N/A | Effects of HA1 (a Probucol Analogue) and ApoC3 siRNA on Lipoprotein-Amyloid Metabolism, Neurovascular Integrity and Cognitive Function in db/db Mice | |
| 尼古丁和吸烟暴露对发育期和成年期小鼠大脑的分子影响 | Gonzalez-Padilla, D. | N/A | Molecular impact of nicotine and smoking exposure on the developing and adult mouse brain | |
| 用于体外和体内神经应用的柔性3D剪纸探针 | Jung, M. | N/A | Flexible 3D kirigami probes for in vitro and in vivo neural applications | |
| 口服Boldine可减轻小鼠神经损伤模型中的胶质细胞激活并预防神经性疼痛 | Pan, J. | N/A | Oral Boldine Administration Attenuates Glia Activation and Prevents Neuropathic Pain in a Murine Spared Nerve Injury Model | |
| 线粒体功能障碍在帕金森病发病机制中损害核孔复合体 | Riaz, Z. | N/A | Mitochondrial dysfunction Impairs the Nuclear Pore Complex in Parkinson's Disease Pathogenesis | |
| 通过GluN2C/GluN2D NMDA受体增强选择性增强中间神经元网络和伽马频段功率 | Camp, C. R. | N/A | Selective Enhancement of the Interneuron Network and Gamma-Band Power via GluN2C/GluN2D NMDA Receptor Potentiation | |
| DNA复制叉速度在皮质神经发生中起到引擎作用 | Wang, J. | N/A | DNA replication fork speed Acts as an Engine in Cortical Neurogenesis | |
| 细胞类型特异性表观基因组编辑在发育中的小鼠皮层中促进中间前体细胞增殖，通过在lncSox1启动子区域靶向H3K9乙酰化 | Sokpor, G. | N/A | Targeted H3K9 acetylation at lncSox1 promoter by cell type-specific epigenome editing promotes intermediate progenitor proliferation in developing mouse cortex | |
| 跨物种神经解剖协变性别差异分析：人类与小鼠的研究 | Pham, L. | N/A | A cross-species analysis of neuroanatomical covariance sex difference in humans and mice | |
| 空间单细胞图谱揭示了扣带-岛叶区域中神经元身份和兴奋性的关键调控因子 | Fodoulian, L. | N/A | A spatial single-cell atlas of the claustro-insular region uncovers key regulators of neuronal identity and excitability | |
| 淀粉样蛋白-β抑制内皮细胞中β-连环蛋白信号通路，损害血管屏障完整性 | Leasure, J. W. | N/A | Inhibition of β-catenin signaling by Amyloid-β in endothelial cells impairs vascular barrier integrity | |
| 在小鼠初级视觉皮层柱中，高效的层状分布相互作用和方向选择性 | Zou, L. | N/A | Efficient laminar-distributed interactions and orientation selectivity in the mouse V1 cortical column | |
| 前注意转移不受扫视幅度的调节 | Zimmermann Bortoluzzi, L. | N/A | Presaccadic attentional shifts are not modulated by saccade amplitude | |
| 解开眼球运动相关的耳膜振荡（EMREOs）：扫视方向和中耳特性如何塑造振幅和时间过程 | Sotero Silva, N. | N/A | Unraveling eye movement-related eardrum oscillations (EMREOs): how saccade direction and middle ear properties shape amplitude and time course | |
| 通过多模态对比学习进行体内细胞类型和脑区分类 | Yu, H. | N/A | In vivo cell-type and brain region classification via multimodal contrastive learning | |
| 一种依赖于CCDC112的新型精子中段形成和附睾成熟过程 | O'Bryan, M. K. | N/A | A novel CCDC112-dependent process of sperm midpiece formation and epididymal maturation | |
| 化学感觉在果蝇中驱动不同的社会行为 | Wu, B. | N/A | Chemosensation drives divergent social behavior in Drosophila | |
| # BioRxiv 2024-11-04 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 从头鉴定通用细胞力学基因特征 | Urbanska, M. | N/A | De novo identification of universal cell mechanics gene signatures | |
| 异常的FGF信号促进SHH亚组婴儿型髓母细胞瘤中的颗粒神经元前体扩张 | Yabut, O. | N/A | Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma | |
| 在单一种类的浮游植物病毒中，高生活史多样性 | Lievens, E. J. | N/A | High life history diversity within a single genus of phytoplankton viruses | |
| 人类新皮层树突中信号传播速度的加快 | Olah, G. | N/A | Accelerated signal propagation speed in human neocortical dendrites | |
| HALO：用于单细胞多组学数据的层次因果建模 | Mao, H. | N/A | HALO: Hierarchical Causal Modeling for Single Cell Multi-Omics Data | |
| 对非生物胁迫的进化反应塑造了物种共存 | Fragata, I. | N/A | Evolution in response to an abiotic stress shapes species coexistence | |
| 内体-溶酶体靶向纳米颗粒递送抗病毒疗法用于冠状病毒感染 | Petcherski, A. | N/A | ENDO-LYSOSOME-TARGETED NANOPARTICLE DELIVERY OF ANTIVIRAL THERAPY FOR CORONAVIRUS INFECTIONS | |
| 在共享酶池中的催化生长确保了中心体大小的稳健控制。 | Banerjee, D. S. | N/A | Catalytic growth in a shared enzyme pool ensures robust control of centrosome size | |
| 在由诱导多能干细胞衍生的神经元中进行的CRISPR筛选揭示了tau蛋白稳态的原理 | Samelson, A. J. | N/A | CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis | |
| LrhA通过增强大肠杆菌中的预激活适应过程，促进了CRISPR-Cas免疫。 | Fang, M. | N/A | LrhA promotes CRISPR-Cas immunity by enhancing primed adaptation in Escherichia coli | |
| 在一种世界性分布的植物谱系中，宏观进化推断出复杂的染色体物种形成模式 | Tribble, C. M. | N/A | Macroevolutionary inference of complex modes of chromosomal speciation in a cosmopolitan plant lineage | |
| 基于进化扩散的蛋白质生成：序列即一切 | Alamdari, S. | N/A | Protein generation with evolutionary diffusion: sequence is all you need | |
| 胺能和肽能对果蝇胰岛素产生细胞的调节作用 | Held, M. | N/A | Aminergic and peptidergic modulation of Insulin-Producing Cells in Drosophila | |
| ElectroPhysiomeGAN：从记录的电生理响应生成生物物理神经元模型参数 | Kim, J. | N/A | ElectroPhysiomeGAN: Generation of Biophysical Neuron Model Parameters from Recorded Electrophysiological Responses | |
| 神经纤毛蛋白-1通过旁分泌调控内皮粘附连接来控制血管通透性。 | Pal, S. | N/A | Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions | |
| CausalXtract：一种从活细胞延时成像数据中提取因果效应的灵活管道 | Simon, F. | N/A | CausalXtract: a flexible pipeline to extract causal effects from live-cell time-lapse imaging data | |
| Pik3r1相关胰岛素抵抗的代谢保护性能量消耗增加并非由Ucp1介导的产热作用所解释。 | Luijten, I. | N/A | The metabolically protective energy expenditure increase of Pik3r1-related insulin resistance is not explained by Ucp1-mediated thermogenesis | |
| 脂质基纳米颗粒细胞周期和自噬相关细胞积累技术平台的构建与应用 | Wang, Y. | N/A | Construction and application of a technical platform for determining cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticles | |
| 基底前脑激活可改善老年猴子的工作记忆 | Pennington, K. R. | N/A | Basal forebrain activation improves working memory in senescent monkeys | |
| 小鼠次级体感皮层和视觉皮层的注意调节 | Petty, G. | N/A | Attentional modulation of secondary somatosensory and visual thalamus of mice | |
| 解决SARS-CoV-2系统发育中的大流行性系统错误 | Hunt, M. | N/A | Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny | |
| 新生C57Bl/6小鼠循环中性粒细胞耗竭的方案 | Mukherjee, D. | N/A | Protocols for circulating neutrophil depletion in neonatal C57Bl/6 mice | |
| 线粒体磷酸泛酰巯基乙胺化对于氧化功能是必需的。 | Norden, P. R. | N/A | Mitochondrial Phosphopantetheinylation is Required for Oxidative Function | |
| 免疫耐受性的个体发育：早期生命分泌型IgA与肠道微生物群相互作用的模型 | Tepekule, B. | N/A | The ontogeny of immune tolerance: a model of early-life secretory IgA - gut microbiome interactions | |
| 物体转移在大脑海马区引发事件编码 | Duan, Y.-L. | N/A | Object-translocation induces event coding in the hippocampus | |
| 胃-脑耦合指数的增加标志着负面心理健康症状的维度特征。 | Banellis, L. | N/A | Increased stomach-brain coupling indexes a dimensional signature of negative mental health symptoms. | |
| 叹息生成于前包钦格复合体 | Cui, Y. | N/A | Sigh generation in preBötzinger Complex | |
| CRF1受体的中断消除了吗啡诱导的雄性小鼠社交性缺陷及催产素能神经元的激活 | Piccin, A. | N/A | Disruption of the CRF1 receptor eliminates morphine-induced sociability deficits and firing of oxytocinergic neurons in male mice | |
| 蚁群人口结构影响蚂蚁的巢穴建造 | Rajendran, H. | N/A | Colony demographics shape nest construction in ants | |
| 多数LCL：基于标签对比学习和多数投票集成方法的疟疾细胞检测 | Kundu, S. | N/A | Majority-LCL: Towards Malaria Cell Detection using Label Contrastive Learning and Majority voting Ensembling | |
| 从混乱的化学到生态学：在具有前生物合理性的化学系统中的自催化与遗传性 | Sokolskyi, T. | N/A | From messy chemistry to ecology: autocatalysis and heritability in prebiotically plausible chemical systems | |
| 基于蛋白质语言的机器学习模型预测腺相关病毒适应性 | Wu, J. | N/A | Prediction of Adeno-Associated Virus Fitness with a Protein Language Based Machine Learning Model | |
| Wnt5a和Notum影响发育中气管软骨间充质凝集的时间动态。 | Bottasso-Arias, N. | N/A | Wnt5a and Notum Influence the Temporal Dynamics of Cartilaginous Mesenchymal Condensations in Developing Trachea. | |
| 对来自加纳萨博巴区和博尔加坦加市的食物源性沙门氏菌和大肠杆菌分离株的基因组特征分析 | Sunmonu, G. T. | N/A | Genomic characterization of foodborne Salmonella enterica and Escherichia coli isolates from Saboba district and Bolgatanga Municipality Ghana | |
| 探究他人的存在：跨脑尺度概率推断揭示增强的兴奋性突触效能 | Esmaeili, A. | N/A | Probing other's Presence: Probabilistic Inference Across Brain Scales Reveals Enhanced Excitatory Synaptic Efficacy | |
| 探究视觉素养技能揭示了学生对染色体的意外认识 | Uminski, C. | N/A | Probing visual literacy skills reveals unexpected student conceptions of chromosomes | |
| 视网膜拓扑编码组织了内部和外部导向的大脑网络之间的相互作用。 | Steel, A. | N/A | Retinotopic coding organizes the interaction between internally and externally oriented brain networks | |
| 大麻烟和口服Δ9THC能增强老年受试者的工作记忆，但对年轻成年受试者则不然。 | Zequeira, S. | N/A | Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects | |
| 针对蛋白水解的疫苗（PROTAVs）用于黑色素瘤的强效联合免疫治疗 | Wang, Q. | N/A | Proteolysis-targeting vaccines (PROTAVs) for robust combination immunotherapy of melanoma | |
| 撤回：通过超快速生物过程减少一氧化二氮排放，实现高浓度N2O的去除 | Maeda, R. | N/A | WITHDRAWN: Mitigating nitrous oxide emission by an ultra-fast bioprocess enabling the removal of high concentration N2O | |
| 乳腺上皮细胞命运转换的分子时间表 | Vallmajo-Martin, Q. | N/A | The molecular chronology of mammary epithelial cell fate switching | |
| 利用肿瘤-免疫动力学综合模型预测慢性髓性白血病患者的无治疗缓解结果 | Fassoni, A. C. | N/A | Predicting treatment-free remission outcomes in Chronic Myeloid Leukemia patients using an integrated model of tumor-immune dynamics | |
| Dnajc3（HSP40）增强小鼠视神经的轴突再生 | Wang, J. | N/A | Dnajc3 (HSP40) Enhances Axon Regeneration in the Mouse Optic Nerve | |
| 通过可逆的YAP和细胞因子控制细胞周期蛋白D1/p27比例的短暂增殖 | Ferrick, K. R. | N/A | Transient proliferation by reversible YAP and mitogen-control of the cyclin D1/p27 ratio | |
| 自主神经和免疫应激反应网络在HIV感染者中的表现 | Mueller, B. R. | N/A | Autonomic and Immune Stress Response Networks in Patients Living With HIV | |
| H2O2 重新利用植物的氧气感应机制来控制对氧化应激的转录反应 | Akter, S. | N/A | H2O2 repurposes the plant oxygen-sensing machinery to control the transcriptional response to oxidative stress | |
| 活体双光子荧光显微镜中神经场的自适应光学校正 | Kang, I. | N/A | Adaptive optical correction for in vivo two-photon fluorescence microscopy with neural fields | |
| 鉴定环素L1作为调节乙型肝炎病毒复制的宿主因子 | Owino, C. O. | N/A | Identification of Cyclin L1 as a host factor regulating Hepatitis B Virus replication | |
| Foxi1通过转录和表观遗传机制调控粘液纤毛发育和离子细胞分化的多个步骤 | Bowden, S. | N/A | Foxi1 regulates multiple steps of mucociliary development and ionocyte specification through transcriptional and epigenetic mechanisms | |
| 听觉皮层中的正交频谱和时间包络表示 | Takahashi, K. | N/A | Orthogonal spectral and temporal envelope representation in auditory cortex | |
| FoldMark：通过水印技术保护蛋白质生成模型 | ZHANG, Z. | N/A | FoldMark: Protecting Protein Generative Models with Watermarking | |
| 剪接因子激酶，即SR蛋白激酶1（SRPK1），对人类乳头瘤病毒生命周期中的晚期事件至关重要。 | Faizo, A. A. A. | N/A | The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycle. | |
| 空间转录组学揭示了生精上皮周期的时间结构及精确的Sertoli-生殖细胞同步化 | Chakravorty, A. | N/A | Spatial Transcriptomics Reveals the Temporal Architecture of the Seminiferous Epithelial Cycle and Precise Sertoli-Germ Synchronization | |
| 稀疏动物社会网络分析 | Mylne, H. K. | N/A | Analysis of sparse animal social networks | |
| 抑制鞭毛钩中赖氨酰丙氨酸交联的物质作为抗螺旋体微生物 | Lynch, M. J. | N/A | Inhibitors of lysinoalanine crosslinking in the flagella hook as antimicrobials against spirochetes | |
| 在猴子前额叶和顶叶皮层中，3D BCI控制的伸手适应过程中，计划和运动活动在运动参考框架内共同适应。 | Ferrea, E. | N/A | Planning and movement activities co-adapt in a motor-reference frame during 3D BCI-controlled reach adaptation in monkey frontal and parietal cortices | |
| 纹状体胆碱能中间神经元的同步激活诱导局部血清素释放 | Matityahu, L. | N/A | Synchronous activation of striatal cholinergic interneurons induces local serotonin release | |
| MethylGPT：一种用于DNA甲基化组的基模型 | Ying, K. | N/A | MethylGPT: a foundation model for the DNA methylome | |
| 适应性峰值的反应规范追踪可能解释化石记录中的时间序列 | Ergon, R. | N/A | Reaction norm tracking of fitness peaks may explain time series in the fossil record | |
| 超越体型二态性：Rensch法则的过去、现在与未来 | Toyama, K. S. | N/A | Beyond size dimorphism: the past, present, and future of Rensch's Rule | |
| 基于Transformer的生存结果预测方法 | Mellors, T. | N/A | A Transformer-Based Approach to Survival Outcome Prediction | |
| 叠加的人动脉内皮细胞产生动脉粥样硬化的脂质条纹并释放促炎性细胞因子 | Zeng, Y. | N/A | Stacked Human Arterial Endothelial Cells Generate Atherosclerotic Fatty Streaks and Release Proinflammatory Cytokines | |
| 汽车尾气中的PM2.5通过ROS-UPRmt信号通路诱导雄性大鼠生殖细胞凋亡 | Wang, C. | N/A | PM2.5 from Automobile Exhaust Induces Apoptosis in Male Rat Germ Cells via the ROS-UPRmt Signaling Pathway | |
| 休眠繁殖体库在塑造群落构建的生态进化动力学中的作用 | Lin, J. | N/A | The role of dormant propagule banks in shaping eco-evolutionary dynamics of community assembly | |
| 长期低流量和非本地鱼类共同作用，改变了山区溪流中昆虫的羽化过程。 | Evangelista, C. | N/A | Prolonged low flows and non-native fish operate additively to alter insect emergence in mountain streams | |
| 多态性串联重复序列塑造了免疫景观中单细胞基因表达的多样性 | Tanudisastro, H. A. | N/A | Polymorphic tandem repeats shape single-cell gene expression across the immune landscape | |
| 药物输送过程模拟 - 量化紫杉醇和聚氧乙烯蓖麻油（Cremophor EL）的构象动力学 | Uddin, M. | N/A | Drug Delivery Process Simulation - Quantifying the Conformation Dynamics of Paclitaxel and Cremophor EL | |
| 利用Halbach阵列和磁性纳米颗粒控制人诱导多能干细胞心肌细胞工程组织中的机电波 | Pozo, M. R. | N/A | Control of electromechanical waves in engineered tissue of human iPSC-cardiomyocytes using a Halbach array and magnetic nanoparticles | |
| 通过软体机器人动态刺激实现生物打印组织可编程三维细胞排列 | Rosalia, L. | N/A | Programmable 3D cell alignment of bioprinted tissue via soft robotic dynamic stimulation | |
| 学习具有多输出高斯过程的单细胞多组学数据的解释性表示 | Moslehi, Z. | N/A | Learning interpretable representations of single-cell multi-omics data with multi-output Gaussian Processes | |
| 强化身份赋予癌细胞癌症特征 | Yang, H. | N/A | Reinforced identity confers cells with cancer hallmarks | |
| 肿瘤缺氧性细胞外囊泡为三阴性乳腺癌创造了一个保护性微环境 | Pachane, B. C. | N/A | Tumoral hypoxic extracellular vesicles create a protective microenvironment for triple-negative breast cancer | |
| 使用维替泊芬抑制Yes相关蛋白（YAP）通过诱导G2M停滞和抑制DNA损伤反应增强脊索瘤的放射敏感性 | Akinduro, O. O. | N/A | Inhibition of Yes-Associated Protein (YAP) with Verteporfin Enhances Radiosensitivity in Chordoma by Inducing G2M Arrest and Inhibiting the DNA Damage Response | |
| 结合不可逆和可逆药物抗性机制的个性化癌症治疗策略 | He, W. | N/A | Personalized cancer treatment strategies incorporating irreversible and reversible drug resistance mechanisms | |
| 具有偏置记忆模式的Hopfield神经网络的鲁棒性 | Montazeri, A. | N/A | Robustness in Hopfield neural networks with biased memory patterns | |
| 一种来自恒河的新型Pbunavirus噬菌体通过下调las/rhl系统及减少KPC碳青霉烯酶，在多重耐药铜绿假单胞菌的废水生物控制中发挥作用。 | Samson, R. | N/A | A novel Pbunavirus phage from the Ganges River in biocontrol of multidrug-resistant Pseudomonas aeruginosa in wastewater by downregulation of las/rhl systems and reduction of KPC carbapenemases | |
| 延迟反馈对基于规则和信息整合类别学习的影响。 | Edmunds, C. E. R. | N/A | The effect of deferring feedback on rule-based and information-integration category learning. | |
| 人类诱导多能干细胞的扰动细胞图谱 | Nourreddine, S. | N/A | A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS | |
| 人类诱导多能干细胞的扰动细胞图谱 | Nourreddine, S. | N/A | A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS | |
| 基于转录组学的FCRL6作为糖尿病肾病新型诊断生物标志物的鉴定 | Marinedrive, A. | N/A | Transcriptomic-Based Identification of FCRL6 as a Novel Diagnostic Biomarker in Diabetic Nephropathy | |
| 口咽癌复发与肿瘤内在及免疫介导的基因组不稳定性降低的后果相关联 | Sannigrahi, M. K. | N/A | Association of oropharyngeal cancer recurrence with tumor-intrinsic and immune-mediated sequelae of reduced genomic instability | |
| 内吞作用通过减弱与BMP信号通路平行的Highwire/PHR1依赖性JNK信号传导，限制了突触的生长。 | Pippadpally, S. | N/A | Endocytosis restricts synapse growth by attenuating Highwire/PHR1-dependent JNK signaling in a pathway parallel to the BMP signaling | |
| 肠道神经元scRNA-seq的青少年和成人元图谱：用于数据集比较和肠道神经元亚型转录组定义的共识 | Benthal, J. T. | N/A | Meta-atlas of Juvenile and Adult Enteric Neuron scRNA-seq for Dataset Comparisons and Consensus on Transcriptomic Definitions of Enteric Neuron Subtypes | |
| 智力和认知灵活性有选择地调节工作记忆功能 | Zhang, H. | N/A | Intelligence and Cognitive Flexibility Selectively Modulate Working Memory Functioning | |
| 归一化动态时间规整提高了区分精神分裂症功能网络连接的敏感性 | Wiafe, S.-L. | N/A | Normalized Dynamic Time Warping Increases Sensitivity In Differentiating Functional Network Connectivity In Schizophrenia | |
| 精神病障碍中孤独感与海马对动态社交刺激反应之间的关联 | McKenna, F. | N/A | Association between loneliness and hippocampal responses to dynamic social stimuli in psychotic disorders | |
| 样本特异性网络分析识别出晚期肾癌免疫治疗反应的基因共表达模式 | Yin, L. | N/A | Sample-specific network analysis identifies gene coexpression patterns of immunotherapy response in advanced kidney cancer | |
| 肿瘤浸润淋巴细胞显示出与三阴性乳腺癌患者化疗反应相关的预后特征 | Banerjee, S. | N/A | Tumor-Infiltrating Lymphocytes Display Prognostic Signatures Associated with Chemotherapy Response in TNBC Patients | |
| 在急性和慢性感染中表征低密度中性粒细胞基因特征及其对疾病严重程度的影响 | de Toledo, M. A. | N/A | Characterizing a Low-Density Neutrophil gene signature in acute and chronic infections and its impact on disease severity | |
| 新皮质第4层神经元对阿尔茨海默病抗性的分子特征 | Dharshini, S. A. P. | N/A | Molecular Signatures of Resilience to Alzheimer's Disease in Neocortical Layer 4 Neurons | |
| 视觉引导的补偿机制减轻聋哑引起的歌声退化 | Rolland, M. | N/A | Visually-guided compensation of deafening-induced song deterioration | |
| 为维持生产力而设计的条带耕作增加了地面甲虫的生物多样性。 | Croijmans, L. | N/A | Strip cropping designed for maintaining productivity increases ground beetle biodiversity | |
| 如何通过部分表型测定来缩短世代间隔，从而帮助提高选育蜜蜂种群的年遗传增益 | Kistler, T. | N/A | How partial phenotyping to reduce generation intervals can help to increase annual genetic gain in selected honeybee populations | |
| 识别和注释着丝粒低甲基化区域与着丝粒双峰区域（CDR）查找器 | Mastrorosa, F. K. | N/A | Identification and annotation of centromeric hypomethylated regions with Centromere Dip Region (CDR)-Finder | |
| 通过X射线晶体学鉴定电压门控钠通道中对挥发性麻醉剂具有功能重要性的结合位点 | Hollingworth, D. | N/A | Functionally important binding site for a volatile anesthetic in a voltage-gated sodium channel identified by X-ray crystallography | |
| 将连续经验整合到深度生成网络中可以解释人类记忆、预测和规划 | Spens, E. | N/A | Consolidation of sequential experience into a deep generative network explains human memory, prediction and planning | |
| ASD相关的CNTNAP2变异体通过受损的胞外域脱落调控破坏神经元树突发育 | Lobete, M. | N/A | ASD-ASSOCIATED CNTNAP2 VARIANTS DISRUPT NEURONAL ARBORIZATION THROUGH IMPAIRED REGULATION BY ECTODOMAIN SHEDDING | |
| 蝇舞迪斯科：用于光遗传学和精细蝇类行为分析的硬件与软件 | Robie, A. A. | N/A | The Fly Disco: Hardware and software for optogenetics and fine-grained fly behavior analysis | |
| 年龄和淀粉样β依赖性神经纤维缠结的启动：一种改进的阿尔茨海默病小鼠模型，不涉及MAPT基因突变。 | Desai, S. | N/A | Age and amyloidβ-dependent initiation of neurofibrillary tau tangles: an improved mouse model of Alzheimers disease without mutations in MAPT. | |
| 伏隔核D2表达神经元：通过节律性光遗传刺激平衡奖励与舔舐中断 | Requejo-Mendoza, N. | N/A | Nucleus accumbens D2-expressing neurons: Balancing reward and licking disruption through rhythmic optogenetic stimulation | |
| 在雄性大鼠中，微胶质细胞的药理学耗竭可防止酒精中毒期间皮质边缘系统的神经退行性变。 | Carlson, E. R. | N/A | Pharmacological depletion of microglia protects against alcohol-induced corticolimbic neurodegeneration during intoxication in male rats | |
| 一种全球性的多巴胺能学习率使得在众多选项中能够进行适应性的觅食行为。 | Grima, L. L. | N/A | A global dopaminergic learning rate enables adaptive foraging across many options | |
| MINT：一个用于分析多元神经信息编码和传输的工具箱 | Lorenz, G. M. | N/A | MINT: a toolbox for the analysis of multivariate neural information coding and transmission | |
| 重复磁刺激通过协同的前后突触活动诱导兴奋性突触的可塑性。 | Galanis, C. | N/A | Repetitive magnetic stimulation induces plasticity of excitatory synapses through cooperative pre- and postsynaptic activity. | |
| F2,6BP恢复亨廷顿病中线粒体基因组的完整性 | Chakraborty, A. | N/A | F2,6BP restores mitochondrial genome integrity in Huntingtons Disease | |
| 用于磁旋转图的体积导体模型 | O'Neill, G. C. | N/A | Volume conductor models for magnetospinography | |
| 耳蜗神经树突长度中的蜗轴-支柱梯度：动态范围中一种新的突触后贡献？ | Kostrikov, S. | N/A | A modiolar-pillar gradient in auditory-nerve dendritic length: a novel post-synaptic contribution to dynamic range? | |
| 在伸手过程中，大脑广泛区域的活动整合了由动作介导的目标预期。 | Peng, Y. | N/A | Brain-wide population activity during reaching integrates action-mediated goal expectation | |
| 光流解析作为因果源分离：一种从光流中同时提取物体和自运动信息的计算模型 | Scherff, M. | N/A | Flow parsing as causal source separation: A computational model for concurrent retrieval of object and self-motion information from optic flow | |
| 通过NrCAM和Ankyrin B，胆囊收缩素-篮状中间神经元对胞体突触的靶向作用 | Oldre, E. N. | N/A | Perisomatic Synaptic Targeting by Cholecystokinin-Basket Interneurons through NrCAM and Ankyrin B | |
| 机械负荷使血影蛋白网络发生“连续”蛋白水解，并促进神经退行性变的早期发作。 | Malaiwong, N. | N/A | Mechanical load conditions the spectrin network to `run-on' proteolysis and promotes early onset neurodegeneration | |
| 人类枕颞皮层中视网膜定位偏差和类别选择性的系统性效应 | Silson, E. H. | N/A | Systematic effects of retinotopic biases and category selectivity across human occipitotemporal cortex | |
| 使用控制理论方法从钙成像预测神经元放电 | Rondoni, N. | N/A | Predicting neuronal firing from calcium imaging using a control theoretic approach | |
| 使用控制理论方法从钙成像预测神经元放电 | Rondoni, N. | N/A | Predicting neuronal firing from calcium imaging using a control theoretic approach | |
| 在小鼠原代皮层神经元的多组学分析中揭示了积雪草成分化合物之间复杂的正负生物相互作用 | Chamberlin, S. R. | N/A | Multi-omics analysis in mouse primary cortical neurons reveals complex positive and negative biological interactions between constituent compounds in Centella asiatica | |
| 通过益生菌和维生素D孕期补充调节产前氯吡硫磷暴露的神经毒性作用：对神经发育和社会性的意外影响 | Ruiz Coca, M. | N/A | Modulating Neurotoxic Effects of Prenatal Chlorpyrifos Exposure Through Probiotic and Vitamin D Gestational Supplementation: Unexpected Effects on Neurodevelopment and Sociability | |
| dArc1调控果蝇糖奖励的评价 | Caron, S. J. C. | N/A | dArc1 controls sugar reward valuation in Drosophila melanogaster | |
| 嵌合音乐揭示了音乐编码的电生理特征中音高与时间之间的相互作用 | Shan, T. | N/A | Chimeric music reveals an interaction of pitch and time in electrophysiological signatures of music encoding | |
| 通过转录抑制和直接CAG重复结合抑制亨廷顿病体细胞不稳定性 | Mathews, E. W. | N/A | Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding | |
| 细菌效应因子筛选揭示RNF214为哺乳动物中的病毒限制因子 | Embry, A. | N/A | Bacterial Effector Screening Reveals RNF214 as a Virus Restriction Factor in Mammals | |
| 猴痘/mpox病毒对细胞坏死和I型干扰素反应的调控。 | Williams, J. | N/A | Regulation of Necroptosis and the Type Interferon Response by Monkeypox/mpox Virus. | |
| 急性三氯生暴露改变非洲爪蟾蝌蚪的线粒体形态和功能，包括正在发育的大脑 | Thomson, A. H. | N/A | Acute Triclosan Exposure Alters Mitochondrial Form and Function in Xenopus laevis Tadpoles, Including the Developing Brain | |
| 精子发生波的自组织协调了小鼠睾丸中持续的精子生成 | Sato, T. | N/A | Self-organization of spermatogenic wave coordinates sustained sperm production in the mouse testis | |
| 依托咪酯作为安乐死成年斑马鱼（Danio Rerio）的有效替代方法 | Schwartz, K. | N/A | Etomidate as an Effective Alternative Method of Euthanizing Adult Zebrafish (Danio Rerio) | |
| 两组分信号网络中激酶和效应子信号逻辑的变化 | Swingle, D. | N/A | Variations in kinase and effector signaling logic in a two component signaling network | |
| 核小体中DNA聚合酶β进行缺口填充DNA合成的结构基础 | Weaver, T. M. | N/A | Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β | |
| 设计的小蛋白能有效抑制并防御中东呼吸综合征冠状病毒（MERS-CoV） | Ragotte, R. J. | N/A | Designed miniproteins potently inhibit and protect against MERS-CoV | |
| 谱系检测器：高效检测新SARS-Cov-2谱系的工具 | Zou, X. | N/A | Lineage Detector: Efficient Tool for Detecting New SARS-Cov-2 Lineages | |
| 机器学习设计的PoLixNano纳米颗粒克服了雾化mRNA疗法的递送障碍 | Zhang, D. | N/A | Machine learning engineered PoLixNano nanoparticles overcome delivery barriers for nebulized mRNA therapeutics | |
| 利用噬菌体展示技术进行合理工程化，以获得更高亲和力的人源化3-磷酸组胺酸特异性抗体 | Martyn, G. D. | N/A | Using phage display for rational engineering of a higher affinity humanized 3-phosphohistidine-specific antibody | |
| PreciCE：通过数据驱动的多基因控制转录网络实现细胞命运的精密工程 | Magnusson, J. P. | N/A | PreciCE: Precision engineering of cell fates via data-driven multi-gene control of transcriptional networks | |
| 大规模抗菌活性调查揭示了健康皮肤微生物群中的新型防御物种 | Nguyen, U. T. | N/A | Large-scale investigation for antimicrobial activity reveals novel defensive species across the healthy skin microbiome | |
| 韦伯病毒是一类感染克雷伯氏菌属的肠道相关噬菌体。 | Dawson, S. J. | N/A | Weberviruses are gut-associated phages that infect Klebsiella spp. | |
| 来自产气荚膜梭菌（Clostridium perfringens）的生物膜基质蛋白通过IV型菌毛相关分泌机制形成分子间异肽键 | Kivimaki, S. E. | N/A | Type IV pili-associated secretion of a biofilm matrix protein from Clostridium perfringens that forms intermolecular isopeptide bonds | |
| 人类JC病毒的染色质模拟 | Schaefer, U. | N/A | Chromatin mimicry by human JC virus | |
| 食品安全细菌动力学的空间特征：共享水处理环境的建模 | Munther, D. | N/A | Spatial characterizations of bacterial dynamics for food safety: Modeling for shared water processing environments | |
| 鉴定新型噻唑衍生物作为登革病毒和日本脑炎病毒蛋白酶抑制剂 | Murtuja, S. | N/A | Identification of novel thiazole derivatives as flaviviral protease inhibitors against DENV and JEV | |
| 作为微生物群落中的一种觅食策略的对抗作用 | Stubbusch, A. K. M. | N/A | Antagonism as a foraging strategy in microbial communities | |
| 微生物在钴胺素偏好上表现出广泛的多样性。 | Mok, K. C. | N/A | Microbes display broad diversity in cobamide preferences | |
| 有氧碳代谢通过调节亚硝酸盐氨化菌以抑制氮素流失——基于旱地农田土壤微宇宙实验的揭示 | Wu, X. | N/A | Aerobic carbon metabolism modulates nitrite ammonifiers for inhibiting nitrogen loss as revealed by microcosm experiment of agricultural upland soil | |
| H3K4me3甲基转移酶KMT2F通过促进RNA聚合酶I的启动前复合物形成来调控核糖体RNA转录。 | Lone, K. | N/A | H3K4me3 methyltransferase KMT2F promotes pre-initiation complex formation by RNA Polymerase I to regulate ribosomal RNA transcription. | |
| 衰老和感染中补体途径和丝氨酸蛋白酶抑制剂激活的时空转录组生态位 | Kern, F. | N/A | Spatiotemporal transcriptomic niches of complement pathway and serine protease inhibitor activation in aging and infection | |
| 利用合成细胞间信号实现分割钟的同步 | Isomura, A. | N/A | Synchronization of the segmentation clock using synthetic cell-cell signaling | |
| 非性腺PIWI蛋白Aubergine调控果蝇成肠中再生干细胞的增殖与肿瘤发生。 | Bellec, K. | N/A | Non-gonadal PIWI protein, Aubergine, regulates regenerative stem cell proliferation and tumourigenesis in the Drosophila adult intestine. | |
| 通过反向激动纳米体揭示的非典型趋化因子受体的组成活性 | Perez Almeria, C. V. | N/A | Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies | |
| 使用AlphaFold2对变构蛋白进行结构分析 | Tyree, S. | N/A | Structural Analysis of a Metamorphic Protein using AlphaFold2 | |
| TRPC1和TRPC5异源四聚体的冷冻电镜结构 | Chen, Y. | N/A | The Cryo-EM structure of TRPC1 and TRPC5 heterotetramer | |
| 药用植物金莲花基因组序列揭示了黄酮类生物合成的见解 | Friedhoff, R. | N/A | Genome sequence of the medicinal plant Tropaeolum majus provides insights into flavonoid biosynthesis | |
| 抗原特异性T细胞受体发现用于治疗进行性多灶性白质脑病 | Gupta, S. | N/A | Antigen-Specific T Cell Receptor Discovery for Treating Progressive Multifocal Leukoencephalopathy | |
| 验证DXS作为分枝杆菌中一个有吸引力的药物靶点 | Mashabela, G. T. | N/A | Validation of DXS as an attractive drug target in mycobacteria | |
| 东部马脑炎病毒E2糖蛋白上的三个正电荷结合位点协同介导了依赖于硫酸乙酰肝素和蛋白受体的感染过程。 | Alcorn, M. D. H. | N/A | Three positively charged binding sites on the eastern equine encephalitis virus E2 glycoprotein coordinate heparan sulfate- and protein receptor-dependent infection | |
| 预测性元组学：微生物组研究中多组学数据稀缺的潜在解决方案 | Cosma, B. M. | N/A | Predicted meta-omics: a potential solution to multi-omics data scarcity in microbiome studies | |
| 机会性病原体广泛存在于在乳制品设施捕获的稳定蝇的可培养外源性和内源性微生物群中。 | Sommer, A. J. | N/A | Opportunistic pathogens are prevalent across the culturable exogenous and endogenous microbiota of stable flies captured at a dairy facility | |
| 从不同环境样本中鉴定新型FosX家族决定因素 | Kieffer, N. | N/A | Identification of Novel FosX Family Determinants from Diverse Environmental Samples | |
| 高分辨率分析负责CCR5内吞作用的arrestin2相互作用 | Petrovic, I. | N/A | A high-resolution analysis of arrestin2 interactions responsible for CCR5 endocytosis | |
| 开放-封闭模最小化算法 | Groot Koerkamp, R. | N/A | The open-closed mod-minimizer algorithm | |
| 全基因组范围内对RPA1和RAD9的映射揭示了利什曼原虫中多顺反子转录、复制起始及复制应激反应的管理机制 | Black, J. A. | N/A | Genome-wide mapping of RPA1 and RAD9 reveals the management of polycistronic transcription, replication initiation, and responses to replication stress in Leishmania | |
| # BioRxiv 2024-11-03 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 多能干细胞的多谱系分化图谱揭示了TMEM88作为哺乳动物血压发育调节因子的作用 | Shen, S. | N/A | A pluripotent stem cell atlas of multilineage differentiation reveals TMEM88 as a developmental regulator of mammalian blood pressure | |
| 进化上多样化的穴样内陷蛋白共享一个围绕两亲性盘状结构构建的共同结构框架 | Han, B. | N/A | Evolutionarily diverse caveolins share a common structural framework built around amphipathic discs | |
| 利用神经风格迁移研究动物信号设计的演变：以一种装饰性鱼类为例 | Hejja-Brichard, Y. | N/A | Using Neural Style Transfer to study the evolution of animal signal design: A case study in an ornamented fish | |
| 动粒蛋白KNL-1调控肌动蛋白细胞骨架以控制树突分支 | Domingos, H. A. | N/A | The Kinetochore Protein KNL-1 Regulates the Actin Cytoskeleton to Control Dendrite Branching | |
| 图拉普拉斯谱、拓扑性质以及结构脑网络的高阶相互作用具有个体特异性、可重复性，但高度依赖于图构建方案。 | Dimitriadis, S. I. | N/A | Graph Laplacian Spectrum, topological properties, and high-order interactions of Structural Brain Networks are Subject-Specific, Repeatable but Highly Dependent on Graph Construction Scheme | |
| 从足月人胎盘中发现的多能细胞类型 | Vadakke-Madathil, S. | N/A | Discovery of a multipotent cell type from the term human placenta | |
| 利用动态因果推断识别促进癌症进展的合作基因 | Cifuentes Bernal, A. | N/A | Identifying cooperative genes causing cancer progression with dynamic causal inference | |
| 神经纤毛蛋白-1通过旁分泌调节内皮粘附连接来控制血管通透性 | Pal, S. | N/A | Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions | |
| 用于肝毒性检测的再生人肝类器官（HLOs）在柱状/灌流板中 | Shrestha, S. | N/A | Regenerative human liver organoids (HLOs) in a pillar/perfusion plate for hepatotoxicity assays | |
| 演变为混沌——传播性与免疫逃逸之间权衡的含义 | Sayyar, G. | N/A | Evolution into chaos - implications of the trade-off between transmissibility and immune evasion | |
| 蛋白质序列和结构的标记化和连续嵌入压缩 | Lu, A. X. | N/A | Tokenized and Continuous Embedding Compressions of Protein Sequence and Structure | |
| 异戊二烯通过启动植物激素反应来驱避植食性昆虫。 | Sahu, A. | N/A | Isoprene deters insect herbivory by priming plant hormone responses | |
| 从共进化动态耦合的图分析中提取的功能重要残基 | Xu, M. | N/A | Functionally Important Residues from Graph Analysis of Coevolved Dynamic couplings | |
| 酵母线粒体中COX1 mRNA翻译激活机制的深入研究 | Zamudio-Ochoa, A. | N/A | Insights into the Translational Activation Mechanisms of the COX1 mRNA in Yeast Mitochondria | |
| Clytia的口面细胞类型与珊瑚幼虫具有共同特征，并将牛磺酸与定殖的调控联系起来。 | Ramon-Mateu, J. | N/A | Aboral cell types of Clytia and coral larvae have shared features and link taurine to the regulation of settlement | |
| 通过体内mRNA递送实现抗原特异性T细胞免疫疗法 | Su, F.-Y. | N/A | Antigen-specific T cell immunotherapy by in vivo mRNA delivery | |
| 蛋白质亚细胞定位预测的深度生成模型 | Yang, L. | N/A | Deep generative model for protein subcellular localization prediction | |
| 蛋白质亚细胞定位预测的深度生成模型 | Yuan, G.-H. | N/A | Deep generative model for protein subcellular localization prediction | |
| 使用Pythia-PPI可靠地预测蛋白质-蛋白质结合亲和力在突变后的变化 | Tao, F. | N/A | Reliable prediction of protein-protein binding affinity changes upon mutations with Pythia-PPI | |
| 畸变校正拼接器：集成光学畸变校正的显微图像拼接 | Cang, H. | N/A | DistortCorrect Stitcher: Microscopy Image Stitching with Integrated Optical Distortion Correction | |
| RvD1 和 LXA4 对心脏电压门控钾通道的抑制作用 | de la Cruz, A. | N/A | RvD1 and LXA4 inhibitory effects on cardiac voltage-gated potassium channels | |
| 具有高级基因组特征的自我认证基因组材料 | Wang, Z. | N/A | Self-Authenticating Genomic Materials with Advanced Genome Signatures | |
| 沙门氏菌效应蛋白SseL通过β-连环蛋白信号轴诱导PD-L1上调和T细胞失活 | Chopra, U. | N/A | Salmonella effector SseL induces PD-L1 up-regulation and T cell inactivation via beta-catenin signalling axis | |
| SloR-SRE与S. mutans mntH启动子的结合具有协同性。 | Ziogas, M. | N/A | SloR-SRE binding to the S. mutans mntH promoter is cooperative. | |
| 一种高通量蛋白质标记工具包，保留了内源性UTR，用于研究动质体中的基因调控。 | Carbajo, C. G. | N/A | A high-throughput protein tagging toolkit that retains endogenous UTRs for studying gene regulation in Kinetoplastids. | |
| 牙形石牙齿基质蛋白1指导石鳖牙齿中的氧化铁沉积 | Nemoto, M. | N/A | Radular teeth matrix protein 1 directs iron oxide deposition in chiton teeth | |
| 小鼠粗线期piRNA切割数百个转录本，但仅改变少数靶标的稳态丰度 | Cecchini, K. | N/A | Mouse Pachytene piRNAs Cleave Hundreds of Transcripts,But Alter the Steady-State Abundance of Only a Minority of Targets | |
| CELF2通过铰链域介导的核凝聚促进tau外显子10的包含 | Li, X. | N/A | CELF2 promotes tau exon 10 inclusion via hinge domain-mediated nuclear condensation | |
| 秋水仙碱抑制小鼠平滑肌细胞表型转换及主动脉夹层 | Jiang, H. | N/A | Colchicine Inhibits Smooth Muscle Cell Phenotypic Switch and Aortic Dissection in Mice | |
| 发育中的小鼠腭单细胞图谱揭示了表皮细胞命运的细胞和分子转变 | Huang, W. | N/A | Single-cell atlas of developing mouse palates reveals cellular and molecular transitions in periderm cell fate | |
| CCR9信号终止受一种不依赖于arrestin的磷酸化机制调控。 | Lamme, T. D. | N/A | CCR9 signal termination is governed by an arrestin-independent phosphorylation mechanism | |
| 模拟膜热蛋白质组分析（MM-TPP）用于绘制膜蛋白-配体动力学图谱 | Jandu, R. S. | N/A | Membrane mimetic thermal proteome profiling (MM-TPP) towards mapping membrane protein-ligand dynamics | |
| 通过生化重建揭示的DNA复制叉稳定和重启机制 | Canal, B. | N/A | DNA replication fork stabilization and restart mechanisms revealed by biochemical reconstitution | |
| 通过增强Wnt/β-catenin信号通路和下调TGF-β/Samd/BMP信号通路，硝酸盐促进C57BL/6小鼠毛发生长 | Lan, Y. | N/A | Nitrate Promoting Hair Growth Through Enhancing Wnt/β-catenin and Downregulating TGF-β/Samd/BMP signaling pathway in C57BL/6 Mice | |
| 一种评估癌症多药耐药性的定量方法 | Ray, A. E. | N/A | A Quantitative Approach for Assessing Multidrug Resistance in Cancer | |
| 使用工程化重组酶将特定DNA插入人类基因组 | Fanton, A. | N/A | Site-specific DNA insertion into the human genome with engineered recombinases | |
| BC-设计：一种高精度逆蛋白质折叠的生物化学感知框架 | Tang, X. | N/A | BC-Design: A Biochemistry-Aware Framework for High-Precision Inverse Protein Folding | |
| 衰老生物标志物的公开竞赛 | Ying, K. | N/A | An Open Competition for Biomarkers of Aging | |
| 代谢调控RNA甲基化由m6A阅读器IGF2BP3介导 | Sharma, G. | N/A | Metabolic regulation of RNA methylation by the m6A-reader IGF2BP3 | |
| 核仁中前rRNA的空间分布与功能组织 | Pan, Y.-H. | N/A | Pre-rRNA spatial distribution and functional organization of the nucleolus | |
| 由HSF1调控的蛋白质稳态网络增强的显性负性TP53突变 | Sebastian, R. M. | N/A | Dominant-negative TP53 mutations potentiated by the HSF1-regulatedproteostasis network | |
| 纽蛋白Y822磷酸化调控心肌细胞粘附动力学及心脏中粘着连接的成熟过程 | Li, X. | N/A | Vinculin Y822 phosphorylation regulates cardiomyocyte adhesion dynamics and adherens junction maturation in the heart | |
| PNPLA3-I148M是一种新形态，干扰了两种主要的肝甘油三酯清除途径。 | Sherman, D. J. | N/A | PNPLA3-I148M is a Neomorph that Interferes with Two Primary Hepatic Triglyceride Clearance Pathways | |
| 资源波动下多物种共存的一个统一原则 | Richardson, J. A. | N/A | A unifying principle for multispecies coexistence under resource fluctuations | |
| PreDigs：一个针对消化细胞注释的特定上下文细胞类型标记和精确细胞亚型的数据库 | Meng, J. | N/A | PreDigs: a Database of Context-specific Cell-type Markers and Precise cell subtypes for Digestive Cell Annotation | |
| 长读长纳米孔全基因组eDNA测序用于河流生物多样性、污染和环境健康监测 | Nousias, O. | N/A | Long-read nanopore shotgun eDNA sequencing for river biodiversity, pollution and environmental health monitoring | |
| 将铁氧还蛋白-NADP+还原酶连接到光系统I上促进了光合循环电子传递 | Emrich-Mills, T. Z. | N/A | Tethering ferredoxin-NADP+ reductase to photosystem I promotes photosynthetic cyclic electron transfer | |
| 核篮的解离会引发衰老酵母中的染色体丢失 | Mirkovic, M. | N/A | Dissociation of the nuclear basket triggers chromosome loss in aging yeast | |
| 剪接体成分GAMETOPHYTIC FACTOR 1（GFA1）调控关键的光周期转换 | Tiedemann, S. | N/A | The spliceosomal component GAMETOPHYTIC FACTOR 1 (GFA1) regulates a key photoperiodic switch | |
| 开发一种用于EV定量的ELISA检测方法，以辅助大规模EV生产 | Zhou, X. | N/A | Development of an ELISA assay for EV quantification to assist the large-scale EV manufacture | |
| 微生物组使N-酰基脂质池多样化——包括由短链脂肪酸衍生的化合物。 | Mannochio-Russo, H. | N/A | The microbiome diversifies N-acyl lipid pools - including short-chain fatty acid-derived compounds | |
| 血小板在早期腹主动脉瘤形成中具有保护作用 | Russell, H. M. | N/A | Platelets are Protective in Early Abdominal Aortic Aneurysm Formation | |
| 高温下植物亚细胞碳水化合物代谢 | Seydel, C. | N/A | Subcellular plant carbohydrate metabolism under elevated temperature | |
| 叶黄素循环在海水藻类Nannochloropsis oceanica中平衡了光保护与光合效率 | Michelberger, T. | N/A | The Xanthophyll Cycle balances Photoprotection and Efficiency in the seawater alga Nannochloropsis oceanica | |
| 许多转录因子家族在植物中具有进化上保守的结合基序 | Zenker, S. | N/A | Many transcription factor families have evolutionarily conserved binding motifs in plants | |
| A型和C型响应调节基因对水稻生长和穗部结构有积极影响 | Rong, C. | N/A | Positive impact of Type-A and -C response regulator genes on growth and panicle architecture in rice | |
| 一种新型顺铂类前药抑制赖氨酸去乙酰化酶，抑制核苷酸切除修复，并克服耐药性 | Negev Korem, Y. | N/A | A Novel Cisplatin-Based Prodrug Inhibits Lysine Deacetylases, Suppresses Nucleotide Excision Repair, and Overcomes Resistance | |
| 草莓（Fragaria x ananassa）中抗疫霉菌2（RPc2）位点的基因组结构 | Han, H. | N/A | Genomic Architecture of the Resistance to Phytophthora Cactorum 2 (RPc2) Locus in Strawberry (Fragaria x ananassa) | |
| 草莓（Fragaria x ananassa）中抗疫霉菌2（RPc2）位点的基因组结构 | Han, H. | N/A | Genomic Architecture of the Resistance to Phytophthora Cactorum 2 (RPc2) Locus in Strawberry (Fragaria x ananassa) | |
| 肾小管上皮细胞中的DNA损伤反应需要nephronophthisis蛋白GLIS2/NPHP7 | Ebert, L. K. | N/A | The nephronophthisis protein GLIS2/NPHP7 is required for the DNA damage response in kidney tubular epithelial cells | |
| 肠道干细胞通过凋亡小体吞噬作用增强局部黏膜免疫 | Zhou, J. Y. | N/A | Intestinal stem cells enhance local mucosal immunity through apoptotic body phagocytosis | |
| 半合成铁蛋白纳米笼用于灵活、位点特异性靶向、簇形成及膜受体激活 | Neusch, A. | N/A | Semisynthetic Ferritin Nanocages for Flexible, Site-specific Targeting, Cluster-formation and Activation of Membrane Receptors | |
| 人类细胞中依赖于检查点的DNA复制叉稳定机制 | Bertolin, A. P. | N/A | The mechanism of checkpoint-dependent DNA replication fork stabilization in human cells | |
| 突触间隙的几何结构通过调节神经递质停留时间来影响NMDAR开放概率 | Hernandez Mesa, M. | N/A | Synaptic cleft geometry modulates NMDAR opening probability by tuning neurotransmitter residence time | |
| 一种协调的激酶和磷酸酶网络调控Stu2招募至酵母动粒 | Stewart, M. G. | N/A | A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores | |
| 在3D BCI控制的伸手适应过程中，猴子的前额叶和顶叶皮层中的运动参考框架内的计划和运动活动共同适应 | Ferrea, E. | N/A | Planning and movement activities co-adapt in a motor-reference frame during 3D BCI-controlled reach adaptation in monkey frontal and parietal cortices | |
| 两种视觉运动适应的学习方式 | Zhang, Y. | N/A | Two ways to learn in visuomotor adaptation | |
| 抑制α7 nAChR活性在脆性X综合征小鼠模型中导致听源性癫痫发作和过度活跃 | Goebel, S. | N/A | Dampened α7 nAChR activity contributes to audiogenic seizures and hyperactivity in a mouse model of Fragile X Syndrome | |
| 研究在轻微足底电击应激后，基因标记的杏仁核神经元中c-Fos的变化 | Dong, H. | N/A | Investigate c-Fos changes in genetically identified amygdala neurons after mild footshock stress | |
| CX3CR1-BAC-Cre的组成型表达在微胶质细胞中引入最小的脱靶效应 | Mroue-Ruiz, F. H. | N/A | Constitutive expression of CX3CR1-BAC-Cre introduces minimal off-target effects in microglia | |
| 产前接触δ-9-四氢大麻酚对小鼠大脑发育的影响：一项从胎儿到成年的磁共振成像研究 | Cupo, L. | N/A | Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study | |
| 睡眠中断改善了简单嗅觉和视觉决策任务中的表现 | Pflitsch, P. | N/A | Sleep Disruption Improves Performance in Simple Olfactory and Visual Decision-Making Tasks | |
| 策略优化源于噪声表示学习 | Brenner, J. W. | N/A | Policy optimization emerges from noisy representation learning | |
| 快速眼动睡眠在海马体中记忆的神经分化过程中所起的作用 | McDevitt, E. A. | N/A | The role of REM sleep in neural differentiation of memories in the hippocampus | |
| 轻度局部冷却可选择性地影响树突树中的计算过程 | Matin, M. H. | N/A | Mild focal cooling selectively impacts computations in dendritic trees | |
| 计算建模显示了支持意识的感觉和前额叶理论的证据。 | Bandara, K. H. | N/A | Computational modelling shows evidence in support of both sensory and frontal theories of consciousness | |
| 关于心智游移和动态思维的神经基础：一项药物和脑刺激研究 | Rasmussen, T. | N/A | On the neural substrates of mind wandering and dynamic thought: A drug and brain stimulation study | |
| 外侧缰核中的神经元-星形胶质细胞耦合介导了抑郁样行为 | Xin, Q. | N/A | Neuron-astrocyte Coupling in Lateral Habenula Mediates Depressive-like Behaviors | |
| 一种双向的脑-脂肪体轴用于病原体规避 | Wang, Y. | N/A | A Bidirectional Brain-Fat Body Axis for Pathogen Avoidance | |
| 新生儿脑室内出血后侧脑室纤毛功能障碍不会导致基于纤毛的脑脊液流动网络的功能变化。 | Pan, S. | N/A | Cilia dysfunction in the lateral ventricles after neonatal intraventricular hemorrhage does not lead to functional changes in cilia-based CSF flow networks | |
| 锥体细胞类型和5-HT2A受体对于赛洛西宾持久药效的发挥至关重要 | Shao, L.-X. | N/A | Pyramidal cell types and 5-HT2A receptors are essential for psilocybin's lasting drug action | |
| 睾丸中体细胞性别认同的转变会引发体细胞中雌性特异性的细胞行为，并在生殖细胞中诱导早期卵母细胞的特化。 | Roach, T. V. | N/A | Conversion of somatic sex identity in the testis induces female-specific cellular behaviors in the soma and early oocyte specification in the germline | |
| 量化生物模式形成的复杂性：通过复杂性度量的新视角 | Riedel, J. H. R. | N/A | Quantifying the intricacies of biological pattern formation: A new perspective through complexity measures | |
| 长寿保障基因LAG1和LAC1在调节酿酒酵母内质网应激和脂质稳态中的不同作用 | MATHIVANAN, A. | N/A | Differential Roles of Longevity Assurance Genes LAG1 and LAC1 in Regulating Endoplasmic Reticulum stress and Lipid Homeostasis in Saccharomyces cerevisiae | |
| 相分离解决与生长相关的电路故障 | Zhang, R. | N/A | Phase Separation to Resolve Growth-Related Circuit Failures | |
| 高通量开发和表征用于人细胞基因调控和表观遗传控制的新型功能性纳米抗体 | Wan, J. | N/A | High-throughput development and characterization of new functional nanobodies for gene regulation and epigenetic control in human cells | |
| 纹状体胆碱能中间神经元的同步激活可诱导局部血清素释放 | Matityahu, L. | N/A | Synchronous activation of striatal cholinergic interneurons induces local serotonin release | |
| 小鼠血吸虫病中的血小板减少症与肝脏巨噬细胞摄取血小板有关，这些巨噬细胞具有独特的激活表型。 | Greenman, J. H. | N/A | Thrombocytopenia in murine schistosomiasis is associated with platelet uptake by liver macrophages that have a distinct activation phenotype | |
| 神经毒性和非神经毒性HIV-1菌株及其Tat蛋白诱导不同的细胞因子-趋化因子谱 | Rao, V. R. | N/A | Neurovirulent and non-neurovirulent strains of HIV-1 and their Tat proteins induce differential cytokine-chemokine profiles | |
| 评估鞋类作为媒介传播意外感染源给小鼠的生物安全风险 | Palillo, M. B. | N/A | Assessing the Biosecurity Risk of Footwear as a Fomite for Transmission of Adventitious Infectious Agents to Mice | |
| 在感染过程中，巨噬细胞会产生一种名为甲基乙二醛的抗菌效应分子。 | Anaya-Sanchez, A. | N/A | Methylglyoxal is an antibacterial effector produced by macrophages during infection | |
| Progerin的积累导致了Hutchinson-Gilford早衰综合征中主动脉平滑肌细胞的丧失 | Kim, P. H. | N/A | The Accumulation of Progerin Underlies the Loss of Aortic Smooth Muscle Cells in Hutchinson-Gilford Progeria Syndrome | |
| 慢性压力会阻碍应激颗粒的形成 | Adachi, Y. | N/A | Chronic stress antagonizes formation of Stress Granules | |
| 解释不同分类水平上土壤细菌群落结构的非生物和生物因素的相对影响 | Mayjonade, B. | N/A | The relative effects of abiotic and biotic factors in explaining the structure of soil bacterial communities at diverse taxonomic levels | |
| 同域分布的Stichopus cf. horrens（棘皮动物门：刺参科）种群基因组分化：基于SNP标记对生殖隔离的见解 | Kim, K. M. | N/A | Genomic divergence of sympatric lineages within Stichopus cf. horrens (Echinodermata: Stichopodidae): Insights on reproductive isolation inferred from SNP markers | |
| 野生鸟类中的卵激素是否具有适应性后果？一项系统综述与元分析 | Mentesana, L. | N/A | Do egg hormones have fitness consequences in wild birds? A systematic review and meta-analysis | |
| 物种共存性在占用模型中能被可靠地推断出来吗？ | Louvrier, J. | N/A | How reliably can species co-occurrence be inferred from occupancy models? | |
| FIGNL1通过解离RAD51纤维，在BRCA2缺陷细胞中抑制同源重组 | Kuthethur, R. | N/A | FIGNL1 inhibits homologous recombination in BRCA2 deficient cells by dissociating RAD51 filaments | |
| 使用原始模板定向扩增技术对胚泡活检标本进行精确的全外显子组分析 | Samitova, A. | N/A | PRECISE EXOME ANALYSIS OF BLASTOCYST BIOPSY SCALE SAMPLES USING PRIMARY TEMPLATE-DIRECTED AMPLIFICATION | |
| 将编码变异等位基因系列测试扩展到汇总统计数据 | McCaw, Z. R. | N/A | Extending the Coding-variant Allelic Series Test to Summary Statistics | |
| JNK的阈值水平通过JAK/STAT激活损伤响应增强子，促进组织再生 | Quinn, J. W. | N/A | A threshold level of JNK activates damage-responsive enhancers via JAK/STAT to promote tissue regeneration | |
| 细菌工程活体材料调节哺乳动物细胞的力学信号传导 | Ostmann, K. | N/A | Bacterial Engineered Living Materials modulate Mechanosignaling in Mammalian Cells | |
| 使用isONclust3对大规模长读长转录组数据进行从头聚类 | Petri, A. J. | N/A | De novo clustering of extensive long-read transcriptome datasets with isONclust3 | |
| MARVEL：通过监督图对比学习进行微环境注释 | CUI, Y. | N/A | MARVEL: Microenvironment Annotation by Supervised Graph Contrastive Learning | |
| 通过热点引导的生成式深度学习进行类药物PPI抑制剂的靶向设计 | Sun, H. | N/A | Target-specific design of drug-like PPI inhibitors via hot-spot-guided generative deep learning | |
| drMD：面向实验学家的分子动力学 | Shrimpton-Phoenix, E. | N/A | drMD: Molecular Dynamics for Experimentalists | |
| Kaizen：使用VQ-VAE分解细胞图像 | Majoral, D. | N/A | Kaizen: Decomposing cellular images with VQ-VAE | |
| 使用机器学习预测延长小鼠寿命的化学化合物 | Belikov, A. V. | N/A | Predicting Mouse Lifespan-Extending Chemical Compounds with Machine Learning | |
| 多上下文种子能够实现快速且高精度的读取映射 | Tolstoganov, I. | N/A | Multi-context seeds enable fast and high-accuracy read mapping | |
| IPMN的空间转录组学揭示了不同惰性和恶性谱系 | Iyer, M. K. | N/A | Spatial Transcriptomics of IPMN Reveals Divergent Indolent and Malignant Lineages | |
| TACSTD2表达标志着结肠腺瘤的早期转变 | Siskova, A. | N/A | TACSTD2 expression marks the early transition to colon adenomas | |
| 使用CSI-TME识别IDH突变型胶质瘤肿瘤微环境中具有预后意义的细胞状态相互作用 | Singh, A. | N/A | Identifying Prognostic Cell State Interactions in the TumorMicroenvironment of IDH-Mutant Gliomas Using CSI-TME | |
| 单细胞AML图谱揭示了t(8;21) AML中与年龄相关的基因调控网络 | Whittle, J. | N/A | Single-Cell Atlas of AML Reveals Age-Related Gene Regulatory Networks in t(8;21) AML | |
| 在一组新型的EGFR酪氨酸激酶抑制剂适应性非小细胞肺癌细胞系中的表型可塑性 | Nanthaprakash, T. | N/A | Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor-adapted non-small cell lung cancer cell lines | |
| 外源性ephrin-A3给药恢复了孕激素处理小鼠的阴道上皮屏障功能 | Liu, M. | N/A | Exogenous ephrin-A3 administration restores vaginal epithelial barrier function in progestin-treated mice | |
| 金雕定期利用重力波在阿尔卑斯山翱翔：高分辨率气象数据带来的新见解 | Carrard, T. | N/A | Golden eagles regularly use gravity waves to soar in the Alps: new insights from high-resolution weather data | |
| 巢或不巢：印度奥里萨邦橄榄海龟大规模筑巢事件的环境提示 | Srikanthan, P. | N/A | To nest or not to nest: environmental cues for olive ridley mass nesting events in Odisha, India | |
| 一种简易且经济高效的微流控装置，采用三维交叉流T型接头生成脱细胞的细胞外基质衍生微载体 | Kamar, F. | N/A | A simple, cost-effective microfluidic device using a 3D cross-flow T-junction for producing decellularized extracellular matrix-derived microcarriers | |
| 基于聚酮合成的多元醇、氨基醇和羟基酸生物合成平台 | Dan, Q. | N/A | A polyketide-based biosynthetic platform for diols, amino alcohols and hydroxyacids | |
| HMGB1介导了巨噬细胞的招募，并在损伤后导致区域性椎间盘组织的生理和力学特性发生改变。 | Burt, K. G. | N/A | HMGB1 mediates macrophage recruitment and regional intervertebral disc tissue functional and mechanical property changes following injury. | |
| BLOC：可构建和可连接的芯片上器官 | Kimura, Y. | N/A | BLOC: buildable and linkable organ on a chip | |
| 从多能干细胞中可调的人CD4+和CD8+ T细胞的差异化 | Jones, R. D. | N/A | Tunable differentiation of human CD4+ and CD8+ T cells from pluripotent stem cells | |
| 综合无偏分析加速动脉粥样硬化中血管组织变化的高分辨率超声结合光声成像技术 | de Jong, A. | N/A | Comprehensive Unbiased Analysis of Vascular Tissue Changes in Accelerated Atherosclerosis Using High-Resolution Ultrasound combined with Photoacoustic Imaging | |
| GeneCover：一种无标签标记基因选择的组合方法 | Wang, A. | N/A | GeneCover: A Combinatorial Approach for Label-free Marker Gene Selection | |
| 从超级字符串到索引：利用掩码Burrows-Wheeler变换（MBWT）为无约束k-mer集合构建空间高效索引 | Sladky, O. | N/A | FroM Superstring to Indexing: a space-efficient index for unconstrained k-mer sets using the Masked Burrows-Wheeler Transform (MBWT) | |
| 通过单细胞和空间转录组学在轻度IgA肾病肾小球内皮细胞中鉴定的炎症分子 | Hasegawa, K. | N/A | Inflammatory molecules in the glomerular endothelium in mild IgA-Nephropathy identified by single-cell and spatial transcriptome | |
| cOmicsArt - 一个可定制的组学分析与报告工具 | Seep, L. | N/A | cOmicsArt - a customizable Omics Analysis and reporting tool | |
| 病理学中人工智能模型的反事实扩散模型用于机制可解释性 | Zigutyte, L. | N/A | Counterfactual Diffusion Models for Mechanistic Explainability of Artificial Intelligence Models in Pathology | |
| 在连锁不平衡不匹配的情况下进行稳健的精细定位 | Zhang, W. | N/A | Robust fine-mapping in the presence of linkage disequilibrium mismatch | |
| 多组学分析揭示了CMTR1在癌症中的上调及其在核糖体蛋白基因表达和肿瘤生长中的作用 | Campeanu, I. J. | N/A | Multi-omics analysis reveals CMTR1 upregulation in cancer and roles in ribosomal protein gene expression and tumor growth | |
| 一种新型体外AML骨髓微环境模型揭示CD44和粘着斑激酶为逆转细胞粘附介导的药物抵抗的治疗靶点 | Ladikou, E. E. | N/A | A novel in-vitro model of the bone marrow microenvironment in AML identifies CD44 and Focal Adhesion Kinase as therapeutic targets to reverse cell adhesion-mediated drug resistance | |
| 关键的分析参数有助于在从组织中提取的RNA中自信地检测表达变化、融合和短变异 | Kubik, S. | N/A | Critical assay parameters facilitating confident detection of expression changes, fusions and short variants in RNA isolated from tissue | |
| 选择具有高生产潜力且对黑果病（BPR）和霜冻果病（FPR）具有耐受性的可可克隆品种。 | Lopez, M. | N/A | Selecting cacao clones with high productivity potential and tolerance to Black Pod Rot (BPR) and Frosty Pod Rot (FPR). | |
| 人类肾小球中拓扑结构不同但功能等效的多条出球小动脉 | Li, J. J. X. | N/A | Topologically distinct and equivalent multiple efferent arterioles in the human glomeruli | |
| 山鸡椒叶甲醇粗提物在动物模型中对抗氧化应激、血栓形成、炎症及大便频率的影响 | Arifuzzaman, S. | N/A | Methanol Crude Extract of Litsea Monopetala Leaves combats oxidative stress, clot formation, inflammation and stool frequency in Animal Model | |
| 慢性给予氟乙基诺美胺（FENM）在小鼠阿尔茨海默病模型中的神经保护作用 | Carles, A. | N/A | Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease | |
| 转录组分析揭示了尼达尼布治疗在大鼠博来霉素模型中与脂质代谢和巨噬细胞参与相关的机制 | Bonatti, M. | N/A | Transcriptomic analysis reveals lipid metabolism and macrophage involvement associated with nintedanib treatment in a rat bleomycin model | |
| 比较Ocimum gratissimum和Jatropha tanjorensis的抗氧化活性 2024。 | Ike, E. C. | N/A | Comparative antioxidant activity of Ocimum gratissimum and Jatropha tanjorensis 2024. | |
| 计算机模拟靶向磷酸二酯酶5及阿赞那加果的催情效果体内评估 | Ejiofor, I. I. | N/A | In-silico Targeting Phosphodiesterase 5 and In-vivo Evaluation of the Aphrodisiac Effect of Azanza garckeana Fruit | |
| 真菌毒素白色念珠菌素在肠道芯片模型中破坏上皮屏障完整性并引发炎症 | Morelli, M. | N/A | Mycotoxin candidalysin impairs epithelial barrier integrity and initiates inflammation in a gut-on-chip model | |
| 发现和分离新型辣椒素及其与TRPV1相关活性 | Smith, J. | N/A | Discovery and isolation of novel capsaicinoids and their TRPV1-related activity | |
| 环境相关铅暴露对SH-SY5Y细胞在整个神经元分化过程中的基因表达产生影响 | Morgan, R. K. | N/A | Environmentally Relevant Lead Exposure Impacts Gene Expression in SH-SY5Y Cells Throughout Neuronal Differentiation | |
| REDD1是决定肾细胞癌对自噬抑制敏感性的一个因素，通过靶向PIM激酶活性可以实现治疗利用。 | Carew, J. S. | N/A | REDD1 is a determinant of the sensitivity of renal cell carcinoma cells to autophagy inhibition that can be therapeutically exploited by targeting PIM kinase activity | |
| 经皮迷走神经刺激可减轻创伤后骨关节炎小鼠模型的疼痛和病情进展 | Yadav, S. | N/A | Transcutaneous Vagus Nerve Stimulation Reduces Pain and OA Progression in Mouse Models of Post-Traumatic Osteoarthritis | |
| ATGL介导的脂解作用对肌细胞线粒体功能至关重要，并能增强PPARδ诱导的线粒体呼吸功能的改善。 | Gemmink, A. | N/A | ATGL-mediated lipolysis is essential for myocellular mitochondrial function and augments PPARδ-induced improvements in mitochondrial respiration | |
| LPS与志贺毒素暴露对培养的人脐静脉内皮细胞RNA表达程序的协同作用。 | Svilar, D. | N/A | Synergy of LPS and Shiga-toxin exposure on the RNA expression program of cultured human umbilical vein endothelial cells. | |
| 真空干燥的公羊精子在室温下保存四年后，其生育力得以保存。 | Moncada, M. | N/A | Fertility Preservation of Vacuum-Dried Ram Spermatozoa Stored for Four Years at Room Temperature | |
| 番茄果实中碳代谢的组织特异性响应对低氧胁迫的反应 | Li, X. | N/A | Tissue-specific responses of the central carbon metabolism in tomato fruit to low oxygen stress | |
| 在耐寒的蟋蟀Gryllus veletis中，HSP70在热应激后上调，但在冷冻应激后并未上调。 | Adams, V. E. | N/A | HSP70 is upregulated after heat but not freezing stress in the freeze-tolerant cricket Gryllus veletis | |
| 蜜蜂对饮食中长期存在的酒精具有抵抗力。 | Ostap-Chec, M. | N/A | Honey bees are resilient to the long-term presence of alcohol in their diet | |
| 豚鼠胎盘hIGF1纳米颗粒基因治疗以胎儿性别特异性的方式改善了胎儿生长受限相关的肝脏脂质和葡萄糖代谢相关信号通路的变化。 | Davenport, B. N. | N/A | Placental hIGF1 nanoparticle gene therapy in guinea pigs ameliorates fetal growth restriction-associated changes in hepatic lipid and glucose metabolism-related signaling pathways in a fetal sex-specific manner | |
| 使用Nav1.5的N端片段进行基因治疗以治疗心脏通道病：一种增强心脏钠电流的新型反式互补机制 | Gizon, M. | N/A | Gene Therapy with the N-terminal Fragment of Nav1.5 for Cardiac Channelopathies: A Novel Transcomplementation Mechanism Potentiating the Cardiac Sodium Current | |
| COSMOS：社区与单微生物优化系统 | Raajaraam, L. | N/A | COSMOS: COmmunity and Single Microbe Optimisation System | |
| 通过同步给药方案来调控癌症免疫周期 | Newton, P. K. | N/A | Gaming the cancer-immunity cycle by synchronizing the dose schedules | |
| MethylGPT：一种用于DNA甲基化组的基础模型 | Ying, K. | N/A | MethylGPT: a foundation model for the DNA methylome | |
| 预测在MetaCyc知识库中注释的代谢物参与的代谢途径 | Huckvale, E. D. | N/A | Predicting the pathway involvement of metabolites annotated in the MetaCyc knowledgebase | |
| C3-C3aR轴调节肺泡巨噬细胞的训练免疫 | Earhart, A. P. | N/A | The C3-C3aR axis modulates trained immunity in alveolar macrophages | |
| 雷帕霉素增强CAR-T细胞在体内控制HIV复制和清除储藏库的作用。 | Zhen, A. | N/A | Rapamycin Enhances CAR-T Control of HIV Replication and Reservoir Elimination in vivo. | |
| KDM6A介导的基因组不稳定性和代谢重编程的丧失，在膀胱癌中对免疫检查点治疗和化疗的反应存在差异性调控。 | Singh, P. | N/A | Loss of KDM6A-mediated genomic instability and metabolic reprogramming differentially regulates responses to immune checkpoint therapy and chemotherapy in bladder cancer. | |
| 抗原流动性调节B细胞免疫突触中抗原捕获的动力学和精确性 | McArthur, H. C. W. | N/A | Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse | |
| 综合应激反应促进巨噬细胞在自身免疫性糖尿病中的炎症和迁移 | Wang, J. E. | N/A | The integrated stress response promotes macrophage inflammation and migration in autoimmune diabetes | |
| 儿童骨髓的单细胞多组学研究揭示了与基质细胞异质性相关的年龄依赖性谱系分化差异 | Hanemaaijer, E. S. | N/A | Single-cell multiomics of pediatric BM reveals age-dependent differences in lineage differentiation linked to stromal cell heterogeneity | |
| 基底膜水凝胶抑制CAR-T细胞激活：纳米纤维素凝胶作为替代品以在三维细胞培养中保持T细胞功能。 | Revilla, S. A. | N/A | Basement membrane hydrogels dampen CAR-T cell activation: nanofibrillar cellulose gels as alternative to preserve T cell function in 3D cell cultures. | |
| 利用血液单细胞转录组学整合内在和系统性免疫衰老 | Tomusiak, A. | N/A | Utilizing blood single-cell transcriptomics to integrate intrinsic and systemic immune aging | |
| 弓形虫感染脑炎模型中不同CD8记忆T细胞亚群 | Moretto, M. M. | N/A | Divergent CD8 memory T cell subsets in an encephalitis model of Toxoplasma gondii infection | |
| 揭示外分泌腺中由ILC2衍生的GM-CSF维持的独特巨噬细胞群体 | Westermann, F. | N/A | Unveiling a unique macrophage population in exocrine glands sustained by ILC2-derived GM-CSF | |
| 脂肪来源基质细胞与人及大鼠胰岛共培养的分泌组分析揭示了具有增强再生能力的特征 | Pinheiro-Machado, E. | N/A | Secretome analysis of human and rat pancreatic islets co-cultured with adipose-derived stromal cells reveals a signature with enhanced regenerative capacities | |
| TET2介导的表观遗传修饰促进2型糖尿病中胰腺β细胞的压力性衰老 | Cai, W. | N/A | TET2-mediated epigenetic modification promotes stress senescence of pancreatic β cells in type 2 diabetes mellitus | |
| 通过培养条件调节脂肪来源基质细胞的分泌组：对血管生成、胶原沉积和免疫调节的影响。 | Pinheiro-Machado, E. | N/A | Modulating adipose-derived stromal cells' secretomes by culture conditions: effects on angiogenesis, collagen deposition, and immunomodulation. | |
| 纤维化肝脏疾病中蛋白质毒性应激的蛋白质组学图谱 | Rosenberger, F. A. | N/A | The proteomic landscape of proteotoxic stress in a fibrogenic liver disease | |
| 微管正端动力学与MOR1聚合酶的周转过程紧密耦合。 | Eng, R. C. | N/A | Microtubule plus-end dynamics are tightly coupled to the turnover of the MOR1 polymerase | |
| 人类苦味受体在人类主动脉和冠状动脉内皮细胞中的表达谱 | Kochany, P. | N/A | Expression Profile of Human Bitter Taste Receptors in Human Aortic and Coronary Artery Endothelial Cells | |
| 等渗介质处理可限制烧伤伤口微生物定植，并促进组织修复。 | Horn, A. | N/A | Isotonic medium treatment limits burn wound microbial colonization and improves tissue repair | |
| 利用慢性胰腺炎患者来源的类器官模型鉴定分子和功能亚型 | Osorio-Vasquez, V. | N/A | Identification of molecular and functional subtypes using chronic pancreatitis patient-derived organoid models | |
| 使用开源软件对全切片脂肪组织图像进行高通量脂肪细胞大小测量 | Ramalho, A. C. | N/A | High-throughput measurement of adipocyte size with open-source software using whole-slide adipose tissue images | |
| BBS/CCT伴侣蛋白复合物确保粘附性G蛋白偶联受体ADGRV1定位于初级纤毛 | Linnert, J. | N/A | The BBS/CCT chaperonin complex ensures the localization of the adhesion G protein-coupled receptor ADGRV1 to primary cilia | |
| 免疫抑制药物对内皮细胞功能表现出不同的影响。 | Elezaby, A. | N/A | Immunosuppression Drugs Exhibit Differential Effects on Endothelial Cell Function | |
| H2S 重塑线粒体超微结构并破坏呼吸超级复合体 | Hanna, D. A. | N/A | H2S remodels mitochondrial ultrastructure and destabilizes respiratory supercomplexes | |
| 一项细胞生物学研究揭示了卵菌效应子运输机制的新见解 | Tomczynska, I. | N/A | A CELL BIOLOGY STUDY REVEALS NEW INSIGHTS INTO THE TRANSPORT MECHANISMS OF OOMYCETE EFFECTORS | |
| 核糖核苷酸还原酶的细胞质定位对于基因组稳定性至关重要 | Andreadis, C. | N/A | Cytoplasmic localization of ribonucleotide reductase is essential for genome stability | |
| 多组学揭示了伤口床微环境分泌信号对巨噬细胞的年龄依赖性代谢重编程 | Forni, M. F. | N/A | Multiomics reveals age-dependent metabolic reprogramming of macrophages by wound bed niche secreted signals | |
| 增强人类诱导多能干细胞的冷冻保存：自下而上与传统冷冻几何形状 | Teodoro, F. | N/A | Enhancing cryopreservation of human iPSCs: Bottom-up vs Conventional freezing geometry | |
| 景观复杂性的生态记忆塑造了淡水群落的多样性。 | Tabi, A. | N/A | The ecological memory of landscape complexity shapes diversity of freshwater communities | |
| 量化猎物在避免鸟类捕食者攻击中，隐蔽、警戒和逃避策略的成功率 | Linke, D. | N/A | Quantifying the success of prey crypsis, aposematism and evasiveness in avoiding avian predators attack | |
| 在鸟类属中，源振幅随着体重的增加而增加。 | Ziegenhorn, M. A. | N/A | Source amplitude increases with body mass across avian genera | |
| 首次尝试使用性标记SSM4和ALLWSex2对长期保存的东北美短吻鲟（Acipenser brevirostrum）血液样本进行多重PCR验证。 | Pozveh, H. S. T. | N/A | First attempt to validate multiplex PCR with sex markers SSM4 and ALLWSex2 in long-term stored blood samples of eastern North American shortnose sturgeon (Acipenser brevirostrum). | |
| 利用时空子采样建模美洲隼下降情况以提高eBird数据可靠性 | Sharma, A. | N/A | Modeling American Kestrel Decline Using Spatiotemporal Subsampling to Improve eBird Data Reliability | |
| 环境DNA揭示了干旱地区临时水体中无脊椎动物群落的时间和空间变异性 | Hedges, B. A. | N/A | Environmental DNA reveals temporal and spatial variability of invertebrate communities in arid-lands ephemeral water bodies | |
| 气候变化对物种生态位概念及分布的影响 | Berti, E. | N/A | The impacts of climate variability on the niche concept and distributions of species | |
| 蜘蛛为理解节肢动物体型变异和性二型性的生态进化驱动因素提供了新的见解。 | Ameline, C. | N/A | Spiders bring new insight into the eco-evolutionary drivers of body size variation and sexual size dimorphism in arthropods | |
| 全骨鱼类基因组揭示了脊椎动物免疫蛋白酶体的进化新奇性，这对MHCI功能具有重要意义。 | Barker, A. V. | N/A | Holostean genomes reveal evolutionary novelty in the vertebrate immunoproteasome that have implications for MHCI function | |
| 综合分析CAM光合作用揭示其对丝兰初级代谢的影响 | Wickell, D. A. | N/A | Integrative analysis of CAM photosynthesis reveals its impact on primary metabolism in Yucca | |
| 尤卡坦半岛咸水洞穴中海绵（多孔动物门，普通海绵纲）的物种多样性与线粒体DNA分析 | Suarez-Moo, P. d. J. | N/A | Species Diversity and Mitochondrial DNA Analysis of Sponges (Porifera, Demospongiae) in an Anchialine Cave on the Yucatan Peninsula | |
| 在慈鲷鱼快速适应辐射过程中的环形物种形成平行案例 | Gautier, G. | N/A | Parallel cases of ring speciation within a rapid adaptive radiation of cichlid fishes | |
| 基因表达和花粉表现表明，在具有不同交配系统的茄属物种之间，交配后选择发生了改变。 | Biewer-Heisler, T. J. | N/A | Gene expression and pollen performance indicate altered postmating selection between Solanum species with different mating systems | |
| 欺骗者在合作持久性中的关键作用 | Babajanyan, S. | N/A | The key role of cheaters in the persistence of cooperation | |
| 英国欧洲貂种群历史性人口下降的特征 | Shaw, R. L. | N/A | Characterisation of the historic demographic decline of the British European polecat population | |
| 病毒和细胞蛋白质组结构域中内在无序性的演变 | Mughal, F. | N/A | Evolution of intrinsic disorder in the structural domains of viral and cellular proteomes | |
| 适应性峰值的反应规范追踪可能解释化石记录中的时间序列 | Ergon, R. | N/A | Reaction norm tracking of fitness peaks may explain time series in the fossil record | |
| 有害藻华形成性浮游藻类中的泛基因组生物学与进化 | Sibbald, S. J. | N/A | Pangenome biology and evolution in harmful algal-bloom-forming pelagophyte algae | |
| 超越体型二态性：Rensch法则的过去、现在与未来 | Toyama, K. S. | N/A | Beyond size dimorphism: the past, present, and future of Rensch's Rule | |
| 用于豹（Panthera pardus）非侵入性基因分型的SNP面板 | Spong, G. | N/A | SNP panel for non-invasive genotyping of leopard (Panthera pardus) | |
| 同义密码子使用定义功能基因家族 | Ghanegolmohammadi, F. | N/A | Synonymous codon usage defines functional gene families | |
| 辣椒（Capsicum annum L.）耐热性遗传多样性分析 | Usmani, S. F. | N/A | Genetic Diversity Analysis for Heat Stress Tolerance in Chili (Capsicum annum L.) | |
| 研究R3HCC1L在胚胎发育和眼科疾病中可能的作用 | Fischer, M. C. | N/A | Investigating a possible role of R3HCC1L in embryonic development and ocular disease | |
| 具有MYT1L杂合突变的小鼠寿命 | Schreiber, A. | N/A | Lifespan in rodents with MYT1L heterozygous mutation | |
| JG2：日本人群特异性参考基因组的更新版本 | Sriwichaiin, S. | N/A | JG2: an updated version of the Japanese population-specific reference genome | |
| StableLift：优化跨基因组构建的种系和体细胞变异检测 | Wang, N. K. | N/A | StableLift: Optimized Germline and Somatic Variant Detection Across Genome Builds | |
| 表观遗传沉默和宿主基因组进化决定了病毒插入在棘阿米巴中的命运 | Blais, C. | N/A | Epigenetic silencing and host genome evolution determine fate of viral insertions in Acanthamoeba | |
| 新兴的特比萘芬耐药性毛癣菌的基因组流行病学 | Rhodes, J. | N/A | Genomic epidemiology of emerging terbinafine-resistant Trichophyton indotineae | |
| 一种用于造血祖细胞和干细胞靶向的模块化逐层纳米颗粒平台 | Dacoba, T. G. | N/A | A Modular Layer-by-Layer Nanoparticle Platform for Hematopoietic Progenitor and Stem Cell Targeting | |
| 主肺动脉的构成性神经网络：发现未被发现的部分 | Vervenne, T. | N/A | Constitutive neural networks for main pulmonary arteries: Discovering the undiscovered | |
| 使用氨基酸进行蛋白质分类的混合Transformer与神经网络配置 | Labiosa, N. | N/A | Hybrid Transformer and Neural NetworkConfiguration for Protein Classification UsingAmino Acids | |
| 低压等容冷冻作为一种可扩展技术用于新鲜食品保存 | Maida, A. | N/A | Low-pressure Isochoric Freezing as a scalable technique for fresh food preservation | |
| 重构mRNA脂质纳米颗粒以实现向胰腺的全身递送 | Isaac, I. | N/A | Reengineering mRNA lipid nanoparticles for systemic delivery to pancreas | |
| 体外骨骼肌构建物的三维生物打印用生物墨水的开发与表征 | Kado Abdalkader, R. | N/A | Development and characterization of bioinks for 3D bioprinting of in vitro skeletal muscle constructs | |
| 基于低RT的鼠肝细胞基因组编辑保真性：挑战与解决方案 | Dunyak, M. T. | N/A | Low RT-based Genome Editing Fidelity in Mouse Hepatocytes: Challenges and Solutions | |
| 通过非内体途径向免疫细胞体外递送mRNA，无需进行核苷修饰。 | Ghoshal, B. | N/A | Ex Vivo Delivery of mRNA to Immune Cells Via a Non-Endosomal Route Obviates the Need for Nucleoside Modification | |
| 免疫学比较：改良小鼠子宫内纤维化模型中菌株与诱导方法的差异 | Hernandez, J. L. | N/A | Immunologic comparisons of strain and induction method in an improved mouse model of intrauterine fibrosis | |
| 在无意中不当处理婴儿时的高重力加速度：对婴儿摇晃综合征诊断的影响 | Lee-Confer, J. S. | N/A | High G-Forces in Unintentionally Improper Infant Handling: Implications for Shaken Baby Syndrome Diagnosis | |
| 基于肌肉的生物混合装置用低成本打印机的可打印树脂的细胞毒性和特性 | Liao, A. S. | N/A | Cytotoxicity and Characterization of 3D-Printable Resins Using a Low-Cost Printer for Muscle-based Biohybrid Devices | |
| 利用水和其自由基进行碰撞诱导和氧附着解离的双重碎裂，实现C=C位点解析的脂质组学 | Takeda, H. | N/A | Dual fragmentation via collision-induced and oxygen attachment dissociations using water and its radicals for C=C position-resolved lipidomics | |
| 一种快速、肌肉驱动的生物混合游泳机器人 | Drennan, W. C. | N/A | A fast, muscle-actuated biohybrid swimming robot | |
| 神经肌肉骨骼建模流程：基于MATLAB的OpenSim模型个性化与治疗优化功能 | Hammond, C. V. | N/A | The Neuromusculoskeletal Modeling Pipeline: MATLAB-based Model Personalization and Treatment Optimization Functionality for OpenSim | |
| 基因表达的多重超声成像 | Nystrom, N. N. | N/A | Multiplexed ultrasound imaging of gene expression | |
| 使用基于贝叶斯优化的迭代实验设计加速细胞培养基开发 | Narayanan, H. | N/A | Accelerating Cell Culture Media Development Using Bayesian Optimization-Based Iterative Experimental Design | |
| RCANE：一种利用RNA-seq数据进行全基因组泛癌种体细胞拷贝数变异预测的深度学习算法 | Ge, C. | N/A | RCANE: A Deep Learning Algorithm for Whole-genome Pan-Cancer Somatic Copy Number Aberration Prediction using RNA-seq Data | |
| DSA-DeepFM：一种用于预测抗癌协同药物组合的双阶段注意力增强DeepFM模型 | Gu, Y. | N/A | DSA-DeepFM: A Dual-Stage Attention-Enhanced DeepFM Model for Predicting Anticancer Synergistic Drug Combinations | |
| AnnSQL：一个基于Python SQL的包，用于在笔记本电脑上进行大规模单细胞基因组学分析 | Pavan, K. | N/A | AnnSQL: A Python SQL-based package for large-scale single-cell genomics analysis on a laptop | |
| Limelight - 一个开源的基于网络的工具，用于可视化、分享和分析来自DDA管道的质谱数据 | Riffle, M. | N/A | Limelight - An open, web-based tool for visualizing, sharing, and analyzing mass spectrometry data from DDA pipelines | |
| Squeakuences：一个便携工具，用于格式化干净无瑕的序列，以消除生物信息学软件的不兼容性 | Forsythe, E. S. S. | N/A | Squeakuences: a portable tool for formatting squeaky-clean sequences to eliminate bioinformatic software incompatibilities | |
| CytoSpatio：利用多范围、多类型点过程模型学习细胞类型的空间关系 | Chen, H. | N/A | CytoSpatio: Learning cell type spatial relationships using multirange, multitype point process models | |
| AlloPool：一种用于蛋白质系统中动态变构网络预测的自适应图神经网络 | Barth, P. | N/A | AlloPool: An Adaptive Graph Neural Network for Dynamic Allosteric Network Prediction in Protein Systems | |
| KOnezumi-AID：一种利用Target-AID自动化设计多重基因敲除的软件 | Taki, T. | N/A | KOnezumi-AID: A Software to Automate the Design of Multiplex Knockouts Using Target-AID | |
| SpaMTP：空间代谢组学和转录组学数据的整合统计分析与可视化。 | Causer, A. | N/A | SpaMTP: Integrative Statistical Analysis and Visualisation of Spatial Metabolomics and Transcriptomics data. | |
| 使用残差神经网络对基因区域中可变剪接事件的差异分析 | Ciccolella, S. | N/A | Differential Analysis of Alternative Splicing Events in gene regions using Residual Neural Networks | |
| DiCARN-DNase: 利用扩张级联ResNet结合自注意力和DNase-seq染色质可及性数据提升细胞间Hi-C分辨率 | Olowofila, S. A. | N/A | DiCARN-DNase: Enhancing Cell-to-Cell Hi-C Resolution Using Dilated Cascading ResNet with Self-Attention and DNase-seq Chromatin Accessibility Data | |
| 克服公共数据库中脊椎动物硒蛋白基因注释的普遍缺陷 | Tico, M. | N/A | Overcoming the widespread flaws in the annotation of vertebrate selenoprotein genes in public databases | |
| 利用空间蛋白质组学和少样本学习对原发组织进行高精度预测，以推断5年无进展黑色素瘤生存率 | Moeller, A. | N/A | High-accuracy prediction of 5-year progression-free melanoma survival using spatial proteomics and few-shot learning on primary tissue | |
| 使用TemSOMap将单细胞RNA测序的谱系解析数据与空间转录组学数据进行映射 | Pan, X. | N/A | Mapping lineage-resolved scRNA-seq data with spatialtranscriptomics using TemSOMap | |
| 量化荧光标记蛋白的核定位 | Hurbain, J. | N/A | Quantifying the nuclear localisation of fluorescently tagged proteins | |
| scRNA-seq与网络传播的联合应用突显了泛癌肿瘤浸润T细胞的关键特征 | MANGELINCK, A. | N/A | The combined use of scRNA-seq and network propagation highlights key features of pan-cancer Tumor-Infiltrating T cells | |
| 检测海洋共生体中的特殊基因：一种系统发育偏差方法识别出增强重组的变体 | Zhou, X. | N/A | Detecting Special Genes in Marine Symbionts: A Phylogeny-Deviation Approach Identifies Recombination-Enhancing Variants | |
| CIWARS：一种基于纵向宏基因组数据的水传播抗生素抗性监测网络服务器 | Emon, M. I. | N/A | CIWARS: a web server for waterborne antibiotic resistance surveillance using longitudinal metagenomic data | |
| BTS：可扩展的贝叶斯组织评分，用于在多组学数据中优先考虑GWAS变异及其功能背景 | Kuksa, P. P. | N/A | BTS: scalable Bayesian Tissue Score for prioritizing GWAS variants and their functional contexts across omics data | |
| AutoPM3：通过LLM驱动的PM3证据提取增强变体解读 | Li, S. | N/A | AutoPM3: Enhancing Variant Interpretation via LLM-driven PM3 Evidence Extraction from Scientific Literature | |
| PEI促进高效基因递送至细胞的分子参数解析 | Montano Gonzalez, P. A. | N/A | Insight Into the Molecular Parameters of PEI Promoting an Efficient Gene Delivery into Cells | |
| 溶酶体阳离子通道TMEM175的选择性通透性与门控机制 | Schulze, T. | N/A | Proton selective conductance and gating of lysosomal cation channel TMEM175 | |
| 临床相关伯克霍尔德菌属产β-内酰胺酶的动态差异 | Gu, J. | N/A | Dynamic Differences in Clinically relevant Pen β-Lactamases from Burkholderia spp. | |
| 探索恶性疟原虫二氢叶酸还原酶的适应性景观：抗叶酸耐药性的进化见解 | Muzata, D. | N/A | Navigating the Fitness Landscapes of Plasmodium falciparum Dihydrofolate Reductase: Evolutionary Insights into Antifolate Resistance | |
| 异质性诱导的受限嵌段共聚物分相 | Mohanta, D. | N/A | Heterogeneity induced Block Copolymer Segregation in Confinement | |
| 基于密度的无偏、可重复聚类优化应用于单分子定位显微镜 | Hammer, J. L. | N/A | Density-based optimization for unbiased, reproducible clustering applied to single molecule localization microscopy | |
| 用于指导低温聚焦离子束铣削超越轴向衍射极限的光学干涉 | Sica, A. V. | N/A | Optical Interference for the Guidance of Cryogenic Focused Ion Beam Milling Beyond the Axial Diffraction Limit | |
| 研究绿色方法合成铜纳米颗粒与电离辐射对乳酸脱氢酶（LDH）的影响 | Sih, B. T. | N/A | Study the Effect of Green Method Synthesis of Copper Nanoparticles with Ionization Radiation on Lactate Dehydrogenase (LDH) | |
| 无模型光子分析扩散型单分子FRET实验 | Terterov, I. | N/A | Model-free photon analysis of diffusion-based single-molecule FRET experiments | |
| Kauffman模型中闭合与开放式进化之间因果关系的证据 | Faggian, M. F. | N/A | Evidence of causality between Closure and Open-Ended Evolution in the Kauffman model | |
| 内在的生物能量适应性变化补偿了HER2驱动的乳腺肿瘤中线粒体含量的减少。 | Frangos, S. M. | N/A | Intrinsic bioenergetic adaptations compensate for reduced mitochondrial content in HER2-driven mammary tumors | |
| 自噬与外泌体途径的相互调控通过GABARAPL2和Alix介导，以促进细胞稳态 | soni, N. | N/A | Reciprocal regulation of autophagy and exosome pathway is mediated by GABARAPL2 and Alix to facilitate cellular homeostasis | |
| 雄激素受体相互作用揭示了内分泌抵抗性乳腺癌中类固醇介导的代谢转变。 | Bleach, R. | N/A | Androgen receptor interactions provide insight into steroid mediated metabolic shifts in endocrine resistant breast cancer. | |
| TET1通过表观遗传重塑和免疫调节在肺腺癌中发挥肿瘤抑制作用 | Rahim, A. | N/A | TET1 Functions as a Tumor Suppressor in Lung Adenocarcinoma Through Epigenetic Remodeling and Immune Modulation | |
| 在胶质母细胞瘤中进行原位单细胞空间分析，评估基质基因表达 | De, A. | N/A | In Situ Single-Cell Spatial Profiling of Matrisome Gene Expression in Glioblastoma | |
| ADAT2/3介导的tRNA编辑促进癌细胞生长和肿瘤发生 | Ramirez-Moya, J. | N/A | ADAT2/3-mediated tRNA editing promotes cancer cell growth and tumorigenicity | |
| XPO1抑制通过调节Wnt/β-连环蛋白信号通路来减少结直肠癌的肿瘤发生。 | Evans, A. E. | N/A | XPO1 inhibition modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis. | |
| 胰腺神经内分泌肿瘤综合RNA剪接图谱揭示了新的临床分子关联 | Blazquez-Encinas, R. | N/A | An integrative RNA spliceosomic landscape of pancreatic neuroendocrine tumors unveils novel clinicomolecular associations | |
| 可遗传的细胞状态塑造了癌细胞中的药物持久性相关性和种群动态 | Iyer, A. | N/A | Inheritable cell-states shape drug-persister correlations and population dynamics in cancer cells | |
| 使用化学合成约束双环肽条件性激活NK细胞功能，针对NKp46和肿瘤表达的抗原 | Dufort, F. J. | N/A | Conditional activation of NK cell function using chemically synthetic constrained bicyclic peptides directed against NKp46 and tumor-expressed antigens | |
| 利用公民科学方法进行以研究为导向的进化论和古生物学教学 | Lautenschlager, S. | N/A | Using a citizen science approach for research-informed teaching of evolution and palaeontology | |
| Nef在南非女性中复制能力强的HIV库长期维持中的作用 | Ismail, S. D. | N/A | The role of Nef in the long-term persistence of the replication-competent HIV reservoir in South African women | |
| 脂肪酸介导的HepaRG细胞中CYP2E1活性的诱导并不系统性地与对乙酰氨基酚的细胞毒性加剧相关。 | Penhoat, C. | N/A | Fatty acid-mediated induction of CYP2E1 activity in HepaRG cells is not systematically associated with exacerbated acetaminophen cytotoxicity | |
| 黄嘌呤氧化还原酶的亚硝酸盐还原酶活性维持心血管健康 | Dyson, N. | N/A | The nitrite reductase activity of xanthine oxidoreductase sustains cardiovascular health | |
| 来自患有肠病的孟加拉国发育迟缓儿童的小肠细菌的代际传递的影响 | Pruss, K. M. | N/A | Effects of intergenerational transmission of small intestinal bacteria cultured from stunted Bangladeshi children with enteropathy | |
| 昆虫识别软件AInsectID版本1.1：基于深度卷积神经网络迁移学习的昆虫物种识别软件 | Sadia, H. | N/A | AInsectID Version 1.1: an Insect Species Identification Software Based on the Transfer Learning of Deep Convolutional Neural Networks | |
| 言论自由在全球范围内预示着动物福利保护 | Montalcini, C. M. | N/A | Freedom of speech predicts animal welfare protection across the globe | |
| ImmunoStruct：整合蛋白质序列、结构和生化特性以进行免疫原性预测与解释 | Givechian, K. B. | N/A | ImmunoStruct: Integration of protein sequence, structure, and biochemical properties for immunogenicity prediction and interpretation | |
| 未锚定的泛素链通过UBXN1促进非经典炎症小体 | Yang, D. | N/A | Unanchored ubiquitin chains promote the non-canonical inflammasome via UBXN1 | |
| 一种新颖的开源培养系统助力建立了首个涉及巨型纤毛虫Zoothamnium niveum的全周期化学合成共生模型系统。 | Contarini, P.-E. | N/A | A novel open-source cultivation system helps establish the first full cycle chemosynthetic symbiosis model system involving the giant ciliate Zoothamnium niveum | |
| 材料性质与细胞效应之间的相互作用驱动了氧化石墨烯与癌细胞和非癌细胞之间不同的相互作用模式。 | Chen, Y. | N/A | Interplay between material properties and cellular effects drives distinct pattern of interaction of graphene oxide with cancer and non-cancer cells | |
| 转录因子聚类的特异性在基因组中被编码 | Dongre, S. | N/A | Specificity in transcription factor clustering is encoded in the genome | |
| 父母谈判策略演变中替代后代抚养模式的涌现 | Zheng, J. | N/A | Emergence of alternative offspring care patterns from the evolution of parental negotiation strategies | |
| 松鼠：从四叶网络或序列比对中重建半有向的系统发育一级网络 | Holtgrefe, N. | N/A | Squirrel: Reconstructing semi-directed phylogenetic level-1 networks from four-leaved networks or sequence alignments | |
| 城市和农村白三叶草种群中选择性清除的特征 | Santangelo, J. | N/A | Signatures of selective sweeps in urban and rural white clover populations | |
| 双相适应性进化抗菌药物耐药性 | Das, S. G. | N/A | Biphasic adaptive evolution of antimicrobial resistance | |
| 在溯祖分化模型中分支大小的分布 | Song, Y. | N/A | The distribution of clade size in a coalescent diversification model | |
| 跨拓扑关联域（TAD）边界的旁观者激活支持了一种依赖于凝聚蛋白的增强子功能枢纽模型 | Williamson, W. I. | N/A | Bystander activation across a TAD boundary supports a cohesin-dependent hub-model for enhancer function | |
| 体内单细胞核糖体分析揭示了衰老过程中细胞类型特异性翻译程序 | Dure, C. | N/A | In vivo single-cell ribosome profiling reveals cell-type-specific translational programs during aging | |
| 创伤应激暴露后，随着时间和组织的变化，转录水平的改变为我们提供了分子层面的见解，揭示了治疗机会窗口的存在。 | McKibben, L. A. | N/A | Transcriptional changes across tissue and time provide molecular insights into a therapeutic window of opportunity following traumatic stress exposure | |
| 通过FUNCODE量化人类和小鼠调控元件的功能保守性 | Fang, W. | N/A | Quantifying Functional Conservation of Human and Mouse Regulatory Elements via FUNCODE | |
| 来自受污染宿主的Kudoa基因组显示出广泛的基因组顺序保守性和快速的序列进化。 | Weber, C. C. | N/A | Kudoa genomes from contaminated hosts reveal extensive gene order conservation and rapid sequence evolution | |
| 人类皮下脂肪组织的单细胞DNA甲基组和三维基因组图谱 | Chen, Z. J. | N/A | Single-cell DNA methylome and 3D genome atlas of the human subcutaneous adipose tissue | |
| 高通量制备胶原微球用于三维细胞培养及胞外囊泡生产 | Ali, S. | N/A | High-throughput Generation of Collagen Microbeads for 3D Cell Culture and Extracellular Vesicle Production | |
| 基于Transformer的生存结果预测方法 | Mellors, T. | N/A | A Transformer-Based Approach to Survival Outcome Prediction | |
| 基于组织学的微卫星不稳定性与免疫治疗反应预测的深度高斯过程及不确定性估计 | Park, S. | N/A | Deep Gaussian Process with Uncertainty Estimation for Microsatellite Instability and Immunotherapy Response Prediction Based on Histology | |
| 评估从单细胞RNA测序数据中构建T细胞受体的方法 | Tian, R. | N/A | Evaluation of T Cell Receptor Construction Methods from scRNA-Seq Data | |
| GenoSiS：一种用于创建动态患者匹配队列的生物库规模基因型相似性搜索架构 | Schneider, K. | N/A | GenoSiS: A Biobank-Scale Genotype Similarity Search Architecture for Creating Dynamic Patient-Match Cohorts | |
| 揭开睡眠之谜：探索新近描述的洛基城堡附近洛基古菌门中的系统发生基因组睡眠信号 | Pandi-Perumal, S. R. | N/A | Unraveling the Mysteries of Sleep: Exploring Phylogenomic Sleep Signals in the Recently Characterized Archaeal Phylum Lokiarchaeota near Loki's Castle | |
| 利用主题建模探索转录组数据的潜在空间 | Valle, F. | N/A | Exploring the latent space of transcriptomic data withtopic modeling | |
| 疾病相关突变会扰乱神经凝聚物的物理性质、组成和RNA翻译。 | Ahangama Liyanage, L. | N/A | Disease-linked mutations dysregulate neuronal condensate physical properties, composition, and RNA translation | |
| 修订的扩散定律允许对膜组织的纳米尺度进行定量表征 | Svobodova, B. | N/A | Revised diffusion law permits quantitative nanoscale characterization of membrane organization | |
| GPCR-G蛋白预偶联与激活的结构基础：从CCR1-Gi复合物中获得的见解 | Shao, Z. | N/A | Structural Basis of GPCR-G Protein Pre-coupling and Activation: Insights from CCR1-Gi Complex | |
| 局部离子条件调节α-突触核蛋白的聚集倾向，并影响其结构多态性。 | Zacharopoulou, M. | N/A | Local ionic conditions modulate the aggregation propensity and influence the structural polymorphism of alpha-synuclein | |
| 一种新的99mTc-PSMA-HBED-CC标记方法 | Phromphao, B. | N/A | A New Labelling Method of 99mTc-PSMA-HBED-CC | |
| β-羟基丁酸代谢的另一途径支持癌细胞中的脂肪酸合成 | Kaluba, F. C. | N/A | An alternative route for β-hydroxybutyrate metabolism supports fatty acid synthesis in cancer cells | |
| 每个癌症细胞的转录组中都编码了患者肿瘤中一种独特的恶性细胞类型。 | Saurty-Seerunghen, M. S. | N/A | A unique malignant cell type per patient tumor is encoded in each cancer cell transcriptome. | |
| 白血病对健康的造血干细胞和祖细胞具有持久的印记。 | Chen, D.-W. | N/A | Leukemia confers a durable imprint on healthy hematopoietic stem and progenitor cells | |
| 利用斑鸠菊叶提取物进行生物银纳米颗粒的植物辅助合成：表征、抗菌、抗炎及急性毒性概况 | Nyuyfoni, G. F. | N/A | Phytoassisted synthesis of biogenic silver nanoparticles using Vernonia amygdalina leaf extract: characterization, antibacterial, anti-inflammatory, and acute toxicity profile | |
| ABRpresto：一种利用子平均间的重采样互相关进行听觉脑干反应自动阈值设定的算法 | Shaheen, L. A. | N/A | ABRpresto: An algorithm for automatic thresholding of the Auditory Brainstem Response using resampled cross-correlation across subaverages | |
| PGR5对于叶绿体和蓝细菌中依赖氧化还原的ATP合酶调控是必需的。 | Nikkanen, L. | N/A | PGR5 is needed for redox-dependent regulation of ATP synthase both in chloroplasts and in cyanobacteria | |
| 结构变异有助于水稻的遗传多样性和杂种优势 | Dan, Z. | N/A | Structural variations contribute to genetic diversity and heterosis in rice | |
| 线粒体效率决定酵母中的克鲁勃效应 | Battjes, J. | N/A | Mitochondrial efficiency determines Crabtree effect across yeasts | |
| 突触和体细胞靶向的ArcLight，一种遗传编码的电压指示器 | Zhong, S. | N/A | Synaptic and Somatic Targeting of ArcLight, a Genetically Encoded Voltage Indicator | |
| 非免疫人血清中的C1q对临床结核分枝杆菌复合体菌株具有非冗余的补体功能。 | Duque, M. A. | N/A | C1q in non-immune human serum has a non-redundant complement function towards clinical Mycobacterium tuberculosis complex strains | |
| 成骨细胞和骨肉瘤中大规模染色体构象的差异调控 | Bisht, M. | N/A | Differential Regulation of Large-scale Chromosome Conformations in Osteoblasts and Osteosarcoma | |
| AURKA通过磷酸化HEC1来控制卵母细胞纺锤体组装检验点和染色体对齐。 | Blengini, C. S. | N/A | AURKA controls oocyte spindle assembly checkpoint and chromosome alignment by HEC1 phosphorylation | |
| SUV39H1介导的KLF4和KDM4A调控协同调节平滑肌细胞表型可塑性 | Chatterjee, P. | N/A | SUV39H1 mediated regulation of KLF4 and KDM4A coordinate smooth muscle cell phenotypic plasticity | |
| 来自软骨中间带的CILP通过Keap1-Nrf2轴抑制早期骨关节炎运动疗法中的透明软骨纤维化和软骨细胞铁死亡 | Jia, S. | N/A | CILP from Cartilage Intermediate Zone Inhibits Hyaline Cartilage Fibrosis and Chondrocyte Ferroptosis via Keap1-Nrf2 Axis in Early Osteoarthritis Exercise Therapy | |
| 使用染色质纤维分析和R-ODD-BLOBS程序建模DNA复制叉的稳定性和崩溃 | Cheng, K. | N/A | Modelling DNA replication fork stability and collapse using chromatin fiber analysis and the R-ODD-BLOBS program | |
| 与选择性伐木和森林再生相关的系统发育和功能组成变化在刚果盆地的热带雨林中 | Depecker, J. | N/A | Phylogenetic and functional compositional shifts associated with selective logging and forest regrowth in tropical rainforests of the Congo Basin | |
| 岛屿人口统计学：哥特兰岛标志性金雕的繁殖动态及驱动因素 | Singh, N. J. | N/A | Island population demography: Breeding dynamics and drivers of Gotland's iconic Golden Eagles | |
| 利用代谢生物标志物绘制病毒分流在广泛分布的颗石藻藻华中的分布图 | Kuhlisch, C. | N/A | Mapping of the viral shunt across widespread coccolithophore blooms using metabolic biomarkers | |
| 环境DNA和野生动物相机陷阱揭示了淡水花岗岩岩池中互补的脊椎动物访问模式 | Hedges, B. A. | N/A | Environmental DNA and wildlife camera traps uncover complimentary vertebrate visitation patterns at freshwater granite rock-holes | |
| 合成基因驱动在种群抑制中的自然选择可以倾向于驱动的中等强度。 | Beaghton, P. J. | N/A | Natural selection of synthetic gene drives for population suppression can favour an intermediate strength of drive | |
| 周期基因改变了亚洲玉米螟的昼夜和季节性时间调控 | Dayton, J. N. | N/A | The period gene alters daily and seasonal timing in Ostrinia nubilalis | |
| 社会家庭结构和生物地理学促进了唯一一种真社会性甲虫——Austroplatypus incompertus（象甲科：Platypodinae亚科）的基因组分化和隐秘物种形成。 | Bickerstaff, J. | N/A | Social family structure and biogeography contribute to genomic divergence and cryptic speciation in the only eusocial beetle species, Austroplatypus incompertus (Curculionidae: Platypodinae) | |
| atad3-null斑马鱼胚胎的转录组分析揭示了可能的疾病机制 | Ezer, S. | N/A | Transcriptome analysis of atad3-null zebrafish embryos elucidates possible disease mechanisms | |
| 多基因评分-罕见变异因果枢轴：复杂疾病遗传学发现的条件性方法 | Shaw, C. A. | N/A | The Polygenic Score - Rare Variant Causal Pivot: A Conditional Approach to Discovery in Complex Disease Genetics | |
| 一个用于CADD评分生成的通用流程：鸡CADD和火鸡CADD | Lensing, K. | N/A | A generic pipeline for CADD score generation: chickenCADD and turkeyCADD | |
| 探索基于微孔的单细胞RNA测序方法（HIVE），用于简化马支气管肺泡灌洗细胞的处理 | Fegraeus, K. | N/A | Exploring a pico-well based scRNA-seq method (HIVE) for simplified processing of equine bronchoalveolar lavage cells | |
| 一种全基因组编码，用于定义细胞类型特异的CTCF结合和染色质组织 | Do, C. | N/A | A genome wide code to define cell-type specific CTCF binding and chromatin organization | |
| 无标记鸟枪法蛋白质组学中监测宿主细胞蛋白质的MS/MS搜索算法比较分析，使用捕获离子迁移和ddaPASEF技术 | Plisnier, M. | N/A | Comparative analysis of MS/MS search algorithms in label-free shotgun proteomics for monitoring host-cell proteins using trapped ion mobility and ddaPASEF | |
| 修饰肽、可编程的DNA四面体用于调节生物系统中的自噬 | Naveena, H. A. | N/A | Peptide modified, programmable DNA tetrahedra to modulate autophagy in biological systems | |
| 利用声学报告基因进行基于细胞的非侵入性成像 | Shivaei, S. | N/A | Non-invasive imaging of cell-based therapies using acoustic reporter genes | |
| qByte：开源等温荧光计，旨在普及核酸、蛋白质和细胞的分析 | Lombardero, F. J. Q. | N/A | qByte: Open-source isothermal fluorimeter for democratizing analysis of nucleic acids, proteins and cells | |
| 长期大变形过程中三维多细胞动力学引起的应变软化和滞后现象 | Tsubota, K.-i. | N/A | Strain softening and hysteresis arising from 3D multicellular dynamics during long-term large deformation | |
| 脉冲场消融过程中热侧效应的定量分析 | Mercado Montoya, M. | N/A | Quantification of thermal side effects during pulsed field ablation | |
| 利用语言引导的视觉模型进行空间蛋白质组学的广义细胞表型分析 | Wang, X. | N/A | Generalized cell phenotyping for spatial proteomics with language-informed vision models | |
| 数据驱动的基因表达特征富集分析优化 | Wenzel, A. T. | N/A | Data driven refinement of gene expression signatures for enrichment analysis | |
| 通过Visium、GeoMx DSP和Chromium方法对存档肿瘤组织进行转录组分析，揭示了患者间和患者内的异质性 | Dong, Y. | N/A | Transcriptome Analysis of Archived Tumor Tissues by Visium, GeoMx DSP, and Chromium Methods Reveals Inter- and Intra-Patient Heterogeneity | |
| 通过种子线性规划与逆折叠和蛋白质语言模型进行抗体库设计 | Hayes, C. F. | N/A | Antibody Library Design by Seeding LinearProgramming with Inverse Folding and ProteinLanguage Models | |
| 使用深度学习方法进行蛋白质复合物物理感知模型精度估计 | Wang, H. | N/A | Physical-aware model accuracy estimation for protein complex using deep learning method | |
| Smile-to-Bert：一种为物理化学性质预测和SMILES嵌入生成而训练的BERT架构 | Barranco-Altirriba, M. | N/A | Smile-to-Bert: A BERT architecture trained for physicochemical properties prediction and SMILES embeddings generation | |
| 利用预训练视觉变换器和大型语言模型进行癫痫发作预测 | Parani, P. | N/A | Utilizing Pretrained Vision Transformers and LargeLanguage Models for Epileptic Seizure Prediction | |
| 基于单基因的AI模型通过整合全基因组CRISPR和组学数据的生物学解释，识别核心及特定环境下的必需基因 | Chou, C.-Y. | N/A | A single-gene-based AI model to identify core and context-specific essential genes by biological interpretation from pooled genome-wide CRISPR and omics data | |
| DGRNA：一种具有双向注意力机制的长上下文RNA基础模型 Mamba2 | Yuan, Y. | N/A | DGRNA: a long-context RNA foundation model with bidirectional attention Mamba2 | |
| 在非结构化环境中导航：评估AlphaFold在预测蛋白质中缺失残基和结构无序方面的有效性 | Zheng, S. | N/A | Navigating the Unstructured by Evaluating AlphaFold's Efficacy in Predicting Missing Residues and Structural Disorder in Proteins | |
| FIBOS：用于分析蛋白质包装和结构的R和Python包 | Soares, H. H. M. | N/A | FIBOS: R and Python packages for analyzing protein packing and structure | |
| 细菌种群聚集模型中非指数反转时间的角色 | Batista, M. | N/A | Role of Non-Exponential Reversal times in Aggregation Models of Bacterial Populations | |
| 评估阿尔茨海默病中淀粉样β和Tau寡聚体的联合神经毒性：一项新标准 | Kuznetsov, A. V. | N/A | Evaluating Combined Neurotoxicity of Amyloid Beta and Tau Oligomers in Alzheimer's Disease: A New Criterion | |
| 上采样点扩散函数（PSF）实现了高精度的三维超分辨率成像，同时保持了稀疏的采样率。 | Chen, J. | N/A | Up sampled PSF enables high accuracy 3D super-resolution imaging with sparse sampling rate | |
| 抑制H3K27M增强的ATM信号通路可提高弥漫中线胶质瘤的放疗效果 | Peterson, E. R. | N/A | Inhibition of H3K27M-enhanced ATM signaling increases radiation efficacy in diffuse midline glioma | |
| HIRA-SETDB1-H3K9me3轴调控慢性髓系白血病细胞的染色质结构 | Shirude, M. B. | N/A | HIRA-SETDB1-H3K9me3 axis regulate chromatin architecture in chronic myeloid leukemia cells | |
| IKAROS促进B细胞急性淋巴母细胞白血病在面对CD19和CD22靶向治疗时的抗原逃逸。 | Domizi, P. | N/A | IKAROS facilitates antigen escape in the face of CD19- and CD22-targeted therapies for B-cell acute lymphoblastic leukemia | |
| CT诊断颞下颌关节骨关节炎的准确性相对于组织病理学发现——一项针对41匹马的离体研究 | Jasinski, T. | N/A | Accuracy of computed tomography in diagnosing temporomandibular joint osteoarthritis relative to histopathological findings - an ex-vivo study of 41 horses | |
| 针对CD38阳性血液系统恶性肿瘤的靶向阿尔法疗法：Ac-巨噬细胞-伊沙妥昔单抗 | Herrero Alvarez, N. | N/A | Targeted Alpha Therapy with Ac-Macropa-Isatuximab for CD38-positive Hematological Malignancies | |
| 缺氧暴露微调海龟细胞的线粒体功能 | Arango, B. G. | N/A | Hypoxia exposure fine-tunes mitochondrial function in sea turtle cells | |
| 着丝粒重复多样性导致啤酒花（Humulus lupulus）中非孟德尔分离模式 | Horakova, L. | N/A | Centromeric repeat diversity underlies non-Mendelian segregation pattern in hop (Humulus lupulus) | |
| 通过信号输入和细胞间通讯调节胰腺β细胞的钙动力学 | Shang, X. | N/A | Tunability of calcium dynamics by signaling inputs and cell-cell communication in pancreatic beta cells | |
| 跨多个数据集的复杂动作停止探索：对动作取消和重新编程机制的洞察 | Salomoni, S. E. | N/A | An exploration of complex action stopping across multiple datasets: Insights into the mechanisms of action cancellation and re-programming | |
| 表达速激肽1的丘脑下核旁亚核神经元控制主动回避学习 | Hu, R. | N/A | Tachykinin1-expressing neurons in the parasubthalamic nucleus control active avoidance learning | |
| 放射性核素疗法的低剂量辐射增强了GD2 TRAC-CAR T细胞在局部神经母细胞瘤中的疗效 | Sodji, Q. H. | N/A | Low Dose Radiation by Radiopharmaceutical Therapy Enhances GD2 TRAC-CAR T Cells Efficacy in Localized Neuroblastoma | |
| 两亲分子工程化的DNA佐剂通过细胞质危险感应刺激淋巴结中强烈的I型干扰素产生，从而在小鼠和非人灵长类动物中诱导强大的细胞和体液免疫。 | Steinbuck, M. P. | N/A | Amphiphile-engineered DNA adjuvants stimulate strong type I IFN production in lymph nodes via cytosolic danger-sensing to induce potent cellular and humoral immunity in mice and non-human primates | |
| 对Fc效应功能的要求可以通过广谱反应性抗α病毒抗体的结合效力来克服。 | Callahan, V. | N/A | Requirement for Fc effector function is overcome by binding potency for broadly reactive anti-alphavirus antibodies | |
| 时空限制的Hippo信号传导指导肝胆细胞的命运和成熟 | Wang, Y. | N/A | Spatiotemporally restricted Hippo signalings instruct the fate and maturation of hepatobiliary cells | |
| 利用成像光谱学在混合温带森林中绘制冠层叶片功能性状图 | Gravel, A. | N/A | Mapping canopy foliar functional traits in a mixed temperate forest using imaging spectroscopy | |
| NANUQ+：一种用于网络估计的分治方法 | Allman, E. S. | N/A | NANUQ+: A divide-and-conquer approach to network estimation | |
| 混合长度基因组测序（blend-seq）：结合短读长与低覆盖度长读长以最大化变异发现 | Magner, R. | N/A | Blended Length Genome Sequencing (blend-seq): Combining Short Reads with Low-Coverage Long Reads to Maximize Variant Discovery | |
| 跨界基因组中人类睡眠相关基因直系同源基因的保守性：来自莱茵衣藻的系统基因组学证据 | Pandi-Perumal, S. R. | N/A | Cross-Kingdom Genomic Conservation of Human Sleep-Related Gene Orthologs: Phylogenomic Evidence from Chlamydomonas reinhardtii | |
| 较长的内含子往往含有更多的串联重复序列，并且经历插入和删除的频率更高。 | Homma, K. | N/A | Longer Internal Exons Tend to Have More Tandem Repeats and Experience Insertions and Deletions More Frequently | |
| # BioRxiv 2024-11-02 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 阳光强度对水稻（Oryza sativa ssp. indica）地方品种开花时间和暴露持续时间的影响 | Deb, D. | N/A | The Effect of Sunlight Intensity on Flower Opening Time and Exposure Duration in Rice (Oryza sativa ssp. indica) Landraces | |
| 一个整合了机制的模型，描述了在单一资源上进行的开发性和干扰性竞争，产生了广泛的共存现象。 | Smith, D. J. B. | N/A | A Mechanistically Integrated Model of Exploitative and Interference Competition over a Single Resource Produces Widespread Coexistence | |
| 精神分裂症相关DRD2基因突变的影响及其与断奶后孤立小鼠模型中社会行为与生化变化的关联 | Mukesh, N. | N/A | Effect of Schizophrenia linked DRD2 gene mutations and correlation of social behavior with biochemical changes in a post-weaning isolated mouse model | |
| 敲除细胞周期依赖性激酶8和19会导致细胞周期蛋白C的耗竭，并抑制小鼠的精子发生和雄性生育能力。 | Bruter, A. V. | N/A | Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice | |
| 不同物种和发育阶段的海马和新皮层中阿片类药物介导的抑制性抑制的差异 | Caccavano, A. P. | N/A | Divergent opioid-mediated suppression of inhibition between hippocampus and neocortex across species and development | |
| 通过双功能HSV载体治疗性疫苗清除慢性SIV感染猕猴体内的病毒潜伏期 | Wen, Z. | N/A | Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques | |
| 使用生成模型预测蛋白质折叠的绝对稳定性 | Cagiada, M. | N/A | Predicting absolute protein folding stability using generative models | |
| 互补的遗传和表观遗传变化有助于快速适应多种全球变化压力 | Brennan, R. | N/A | Complementary genetic and epigenetic changes facilitate rapid adaptation to multiple global change stressors | |
| 放射科医生感知错误的神经认知机制：初步研究结果 | Bruno, M. A. | N/A | Neurocognitive Mechanism of Radiologists Perceptual Errors: Results of Preliminary Studies | |
| Dnajc12敲除小鼠的特征分析，作为低多巴胺能的模型 | Deng, I. B. | N/A | Characterization of Dnajc12 knockout mice, a model of hypodopaminergia | |
| 一种经济实惠的解决方案，用于研究斑胸草雀颅内脑电图（iEEG）信号 | Abolghasemi, M.-M. | N/A | An affordable solution for investigating zebra finch intracranial electroencephalography (iEEG) signals | |
| 利用DNA折纸纳米块对果蝇E-钙粘蛋白外域片段及其相互作用的纳米尺度可视化研究 | Oda, H. | N/A | Nanoscale visualization of Drosophila E-cadherin ectodomain fragments and their interactions using DNA origami nanoblocks | |
| 身体自主感神经相关性 | Regev Krugwasser, A. | N/A | Neural Correlates of the Embodied Sense of Agency | |
| m6A RNA修饰在转录后水平上调控突触功能，这一过程在衰老以及突触核蛋白病的小鼠模型中发挥作用。 | Chopra, A. | N/A | The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy | |
| 视神经头处的轴突运输受损在新型Cre诱导的小鼠青光眼模型中促进了神经退行性变 | Kaipa, B. R. | N/A | Impaired axonal transport at the optic nerve head contributes to neurodegeneration in a novel Cre-inducible mouse model of myocilin glaucoma | |
| p24家族成员TMED9通过快速内质网应激诱导的出口途径，协调错误折叠的GPI锚定蛋白从内质网到高尔基体的清除。 | Ronzier, E. | N/A | The p24-family member, TMED9, coordinates clearance of misfolded GPI-anchored proteins from the ER to the Golgi via the Rapid ER Stress-Induced Export pathway | |
| 视觉特征注意力控制的分层组织 | Meyyappan, S. | N/A | Hierarchical Organization of Visual Feature Attention Control | |
| 阻止BMP4前域磷酸化的突变会损害同源二聚体的蛋白水解成熟，导致小鼠早期死亡。 | Kim, H.-s. | N/A | Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to early lethality in mice | |
| 一种针对鲍曼不动杆菌的新型烈性噬菌体：在小鼠肺部感染模型中的疗效和安全性 | Wang, J. | N/A | A Novel Genus of Virulent Phage Targeting Acinetobacter baumannii: Efficacy and Safety in a Murine Model of Pulmonary Infection | |
| 表观基因组的趋同进化在生命之树中招募了DNA修复 | Monroe, G. | N/A | Convergent evolution of epigenome recruited DNA repair across the Tree of Life | |
| 人类抗体识别的流感H1和H3血凝素上的保守位点 | Maurer, D. P. | N/A | Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies | |
| 从光栅响应构建的编码流形在皮层视觉区域中组织了对自然场景的响应 | Dyballa, L. | N/A | Encoding manifolds constructed from grating responses organize responses to natural scenes in cortical visual areas | |
| 后顶叶皮层介导了由稀有性引发的决策偏差以及在不确定性下的学习过程。 | Sheng, W. | N/A | Posterior parietal cortex mediates rarity-induced decision bias and learning under uncertainty | |
| C9orf72扩展导致不稳定的叶酸敏感脆弱位点FRA9A的形成。 | Mirceta, M. | N/A | C9orf72 expansion creates the unstable folate-sensitive fragile site FRA9A | |
| 类噬菌体CRISPR样调控RNA沉默细菌的适应性和先天免疫 | Liu, C. | N/A | Phage CRISPR-like regulatory RNAs silence bacterial adaptive and innate immunity | |
| 简化胎鼠影像中的不对称量化：基于专家指导的半自动化流程 | Rolfe, S. M. | N/A | Streamlining Asymmetry Quantification in Fetal Mouse Imaging: A Semi-Automated Pipeline Supported by Expert Guidance | |
| Q_ST--F_ST比较中的错误率取决于遗传结构和估计程序 | Liu, J. J. | N/A | Error rates in Q_ST--F_ST comparisons depend on genetic architecture and estimation procedures | |
| 通过全基因组比较谱系地理学揭示的新热带山地与低地鸟类显著的种内多样化动态差异 | Wacker, K. S. | N/A | Distinct intraspecific diversification dynamics in Neotropical montane versus lowland birds revealed by whole-genome comparative phylogeography | |
| 基因组学和抗性检测有助于管理两种遭受入侵性桃金娘锈病病原体严重破坏的树种 | Chen, S. H. | N/A | Genomics and resistance assays inform the management of two tree species being devastated by the invasive myrtle rust pathogen | |
| 在严重肺炎链球菌肺炎的小鼠模型中，中性粒细胞转录组分化为两条截然不同的轨迹 | Pihl, R. M. F. | N/A | Neutrophil transcriptome diverges into two discrete trajectories in a murine model of severe Streptococcus pneumoniae pneumonia | |
| Lowe综合征中神经发生缺陷是由线粒体丢失和与纤毛相关的音猬因子缺陷引起的。 | Lo, C. | N/A | Defective Neurogenesis in Lowe Syndrome is Caused by Mitochondria Loss and Cilia-related Sonic Hedgehog Defects | |
| 补偿性进化以应对DNA复制压力对营养物质的可用性具有鲁棒性 | Natalino, M. | N/A | Compensatory Evolution to DNA Replication Stress is Robust to Nutrient Availability | |
| GDF5的复杂调控相互作用塑造了关节形态和骨关节炎疾病风险 | Coveney, C. R. | N/A | Complex regulatory interactions at GDF5 shape joint morphology and osteoarthritis disease risk | |
| 人乙型肝炎病毒向新热带野生灵长类动物的跨物种传播 | boubli, J. | N/A | Cross-species transmission of human hepatitis B virus to wild Neotropical primates | |
| 高通量、多重定量及单分子水平上的单个外泌体分选 | Park, J. | N/A | High-throughput, multiplexed quantification, and sorting of single EVs at single-molecule level | |
| 用于单细胞数据整合的图正则化最优传输 | Wang, Z. | N/A | Graph-Regularized Optimal Transport for Single-Cell Data Integration | |
| 使用可交换的寡核苷酸标签实现高吞吐量的单分子显微镜，具有可调节的空间分辨率 | de Zwaan, K. | N/A | High-throughput single molecule microscopy with adaptable spatial resolution using exchangeable oligonucleotide labels | |
| 左星状神经节与右星状神经节神经元的电生理比较 | Verkerk, A. O. | N/A | Electrophysiological comparison of left versus right stellate ganglia neurons | |
| 单细胞、空间和命运图谱分析揭示了耳蜗髓系细胞的微环境依赖性多样性。 | Chiot, A. | N/A | Single-cell, spatial, and fate-mapping analyses uncover niche dependent diversity of cochlear myeloid cells. | |
| 夏威夷短尾鱿鱼早期阶段对海洋变暖和酸化的发育及转录组反应 | Otjacques, E. | N/A | Developmental and transcriptomic responses of Hawaiian bobtail squid early stages to ocean warming and acidification | |
| 通过动力学限制的溶液相索引技术，实现了快速、简便且无需仪器的单细胞转录组分析 | Marafini, P. | N/A | Solution-phase indexing by kinetic confinement enables rapid, simple, and instrument-free single cell transcriptional profiling | |
| 癌症基金会：一种单细胞RNA测序基础模型，用于解析癌症中的药物抗性 | Theus, A. | N/A | CancerFoundation: A single-cell RNA sequencing foundation model to decipher drug resistance in cancer | |
| MAPK信号通路调控植物细胞中DCP1在P-体与应激颗粒间的分配 | He, S.-L. | N/A | MAPK signaling modulates the partition of DCP1 between P-bodies and stress granules in plant cells | |
| 植物内化学防御的变异并不能解释小菜蛾对Erysimum cheiranthoides的取食偏好。 | Zuest, T. | N/A | Within-plant variation in chemical defence of Erysimum cheiranthoides does not explain Plutella xylostella feeding preference | |
| 稀有物种对高山植物群落系统发育多样性的贡献并不不成比例 | Veldhuisen, L. N. | N/A | Rare species do not disproportionately contribute to phylogenetic diversity in a subalpine plant community | |
| 四个ZIP基因在根的外部区域参与了锌、铁、铜和锰的吸收过程。 | ROBE, K. | N/A | Four ZIPs contribute to Zn, Fe, Cu and Mn acquisition at the outer root domain | |
| 一种超保守的ARF-DNA界面是生长素触发的转录反应的基础 | Rienstra, J. | N/A | An ultra-conserved ARF-DNA interface underlies auxin-triggered transcriptional response | |
| 确保科学研究的稳健性：以分根实验为例 | Salvatore, L. | N/A | Ensuring Robustness in Scientific Research, Split-root assays as an example case | |
| 早期分支蓝藻Anthocerotibacter panamensis中光系统I的结构与演化 | Jiang, H.-W. | N/A | Structure and evolution of Photosystem I in the early-branching cyanobacterium Anthocerotibacter panamensis | |
| SOQ1 在拟南芥叶绿体液泡中作为甲硫氨酸亚砜还原酶，用于调节光保护性 qH。 | Hao, J. | N/A | SOQ1 functions as a methionine sulfoxide reductase in the chloroplast lumen for regulation of photoprotective qH in Arabidopsis | |
| 复杂鞘脂类在藓类植物小立碗藓的细胞分裂和质膜孔形成中起着至关重要的作用。 | Wegner, L. | N/A | Complex sphingolipids are essential for cell division and plasmodesmal development in the moss Physcomitrium patens | |
| 大豆种子产量、蛋白质和油脂的基因组和表型预测 | Van der Laan, L. | N/A | Genomic and Phenomic Prediction for Soybean Seed Yield, Protein, and Oil | |
| 特定物种叶际对外部pH变化的响应 | Lopez Gonzalez, C. | N/A | Species-specific phyllosphere responses to external pH change | |
| 动物RNA病毒的基因组大小反映了系统发育的限制 | Takada, K. | N/A | Genome sizes of animal RNA viruses reflect phylogenetic constraints | |
| 通过导管感染H5N1亚型2.3.4.4b流感病毒 | Roubidoux, E. K. | N/A | Intraductal infection with H5N1 clade 2.3.4.4b influenza virus | |
| 来自印度恒河原始河段的新型Tequatrovirus噬菌体在减少污水细菌负荷中的特性研究 | Samson, R. | N/A | Characterization of a Novel Tequatrovirus Phage from Pristine Stretch of The Ganges River, India, in Reducing Bacterial Load from Sewage Water | |
| 抑制鞭毛钩中赖氨酰丙氨酸交联的物质作为抗螺旋体微生物 | Lynch, M. J. | N/A | Inhibitors of lysinoalanine crosslinking in the flagella hook as antimicrobials against spirochetes | |
| 微生物裂解物作为细胞农业培养基配方中的低成本血清代用品 | Dolgin, J. | N/A | Microbial lysates as low-cost serum replacements in cellular agriculture media formulation | |
| AnnotIEM：基于16S基因微生物测序的微生物组物种水平注释新工具 | Bhatttacharyya, M. | N/A | AnnotIEM: novel tool for microbiome species-level annotation of 16S gene based microbial sequencing | |
| 乳腺肿瘤微生物群调节抗肿瘤免疫和T细胞相关代谢物 | Liu, C.-C. | N/A | Breast tumor microbiome regulates anti-tumor immunity and T cell-associated metabolites | |
| 水稻植株中干旱诱导的活性氧调节与对黄单胞菌感染的抗性之间的相声 | Ramu, D. S. | N/A | Crosstalk Between Drought-Induced ROS Regulation and Resistance to Xanthomonas oryzae Infection in Rice Plants | |
| 独脚金内酯参与促进玉米对铁的吸收 | Fili, S. | N/A | Strigolactones are involved in enhancing iron uptake in maize | |
| 通过多模态方法表征高粱和亚麻荠对环境胁迫的响应 | Seitz, K. A. | N/A | Characterizing the Responses of sorghum and Camelina to Environmental Stress through a Multi-Modal Approach | |
| 通过Ca2+传感器调控TIR信号传导，激活ADR1对pRib-AMP-EDS1-PAD4的识别，从而启动气孔免疫机制。 | Wang, H. | N/A | Switch of TIR signaling by a Ca2+ sensor activates ADR1 recognition of pRib-AMP-EDS1-PAD4 for stomatal immunity | |
| 利用多环境试验育种数据优化基因型特异性参数评估木薯作物生长模型 | Okoma, P. M. | N/A | Evaluating a Cassava Crop Growth Model by Optimizing Genotypic-Specific Parameters Using Multi-environment Trial Breeding Data | |
| 调控玉米杂交种中异交相关基因表达互补的机制 | Pitz, M. | N/A | Regulation of heterosis-associated gene expression complementation in maize hybrids | |
| 广泛分布的野生植物在陡峭气候梯度下配子体性状对热胁迫的适应与驯化 | Tushabe, D. | N/A | Adaptation and acclimation of gametophytic traits to heat stress in a widely distributed wild plant along a steep climatic gradient | |
| 光温巧合检测器的遗传结构 | Seluzicki, A. | N/A | Genetic architecture of a light-temperature coincidence detector | |
| 数学模型指导最佳杀菌剂使用，以防治大豆菌核茎腐病，从而最大化大豆生产利润。 | Byer, T. | N/A | A mathematical model informs optimal fungicide use against Sclerotinia stem rot to maximize profits in soybean production | |
| 豆科（蝶形花亚科）植物中一些重要特征的可能多重起源 | Aygoren Uluer, D. | N/A | POSSIBLE MULTIPLE ORIGINS OF SOME IMPORTANT CHARACTERISTICS OF THE KEEL (PAPILIONATE) FLOWERS WITHIN FABALES | |
| 拟南芥SUFB和CLP蛋白酶调控SUFBC2D以操控叶绿体中铁硫簇的生物合成 | Cheng, Y. | N/A | Arabidopsis SUFB and CLP protease regulate SUFBC2D to manipulate iron-sulfur cluster biosynthesis in chloroplast | |
| LysR型转录因子PacR在调控Anabaena sp. PCC7120氮代谢中的作用 | Werner, E. | N/A | The role of the LysR-type transcription factor PacR in regulating nitrogen metabolism in Anabaena sp. PCC7120 | |
| 异戊二烯通过启动植物激素反应来驱避食草昆虫。 | Sahu, A. | N/A | Isoprene deters insect herbivory by priming plant hormone responses | |
| 通过一个结构化的跨专业培训项目，提升护理人员管理1型糖尿病患儿的能力 | Juhi, A. | N/A | Building capacity among caregivers for managing children with Type 1 Diabetes Mellitus through a structured Interprofessional training program | |
| 基于网络的表征学习揭示了时间和饮食对婴儿肠道微生物和代谢环境的影响 | Price, A. | N/A | Network-based representation learning reveals the impact of time and diet on the gut microbial and metabolomic environment of infants | |
| 锌能增强一种反翻译抑制剂的效力，这种抑制剂能杀死结核分枝杆菌和非结核分枝杆菌。 | Varshney, A. | N/A | A trans-translation inhibitor is potentiated by zinc and kills Mycobacterium tuberculosis and non-tuberculous mycobacteria | |
| 一种需要用于粘细菌胆固醇生产的香叶基香叶基还原酶同源物 | Lee, A. K. | N/A | A geranylgeranyl reductase homolog required for cholesterol production in Myxococcota | |
| 胶原蛋白结合粘附素限制金黄色葡萄球菌皮肤感染 | Bhattacharya, M. | N/A | Collagen binding adhesin restricts Staphylococcus aureus skin infection | |
| 在阿根廷恩特雷里奥斯省瓜莱瓜伊丘市患有阴道念珠菌病的育龄女性患者中分离出的念珠菌种 | Perez Duarte, I. R. | N/A | Candida species isolated in female patients of reproductive age with vaginal candidiasis in Gualeguaychu, Entre Rios, Argentina | |
| 使用BONCAT解析金黄色葡萄球菌持久性菌株的蛋白质组 | George Matlalcuatzi, E. D. C. | N/A | Using BONCAT To Dissect The Proteome Of S. aureus Persisters | |
| 特定连接泛素化靶向破坏揭示了K29连接泛素化在表观基因组完整性中的关键作用 | Arroyo-Gomez, J. | N/A | Targeted disruption of linkage-specific ubiquitylation reveals a key role of K29-linked ubiquitylation in epigenome integrity | |
| 利用固定在无人驾驶飞行器上的轻便便携式空气采样器检测加州中央谷地空气中的球孢子菌孢子 | Radosevich, M. T. | N/A | Detection of airborne Coccidioides spores using lightweight portable air samplers affixed to uncrewed aircraft systems in California's Central Valley | |
| PAL-AI揭示了在卵母细胞成熟过程中控制多聚腺苷酸尾长度的遗传决定因素，这些因素与人类生育能力相关。 | Xiang, K. | N/A | PAL-AI reveals genetic determinants that control poly(A)-tail length during oocyte maturation with relevance to human fertility | |
| 研究短链脂肪酸对结直肠癌中细胞外囊泡生成的影响 | Macedo, D. | N/A | Investigating Short-Chain Fatty Acids Effects on Extracellular Vesicles Production in Colorectal Cancer | |
| 陆地蛞蝓Ambigolimax valentianus的耐寒性 | Gill, L. T. | N/A | The cold tolerance of the terrestrial slug, Ambigolimax valentianus | |
| 适应毒物的北大西洋青鳉鱼（Fundulus heteroclitus）在低氧条件下基因表达和DNA甲基化变化 | Aluru, N. | N/A | Gene expression and DNA methylation changes in response to hypoxia in toxicant-adapted Atlantic killifish (Fundulus heteroclitus) | |
| 人类巨噬细胞反应与L. (V.) panamensis对五价锑的自然抗性之间的相互作用 | Fernandez, O. L. | N/A | Interplay of human macrophage response and natural resistance of L. (V.) panamensis to pentavalent antimony | |
| 胚胎肥大细胞来源于表达Cpa3的祖细胞，与粒细胞-单核细胞祖细胞无关 | Ma, W. | N/A | Embryonic Mast Cells Arise from Cpa3-expressing Precursors Independent of Granulocyte-Monocyte Progenitors | |
| 一个PI3Kδ-Foxo1-FasL信号放大环路重新编排了CD4+辅助T细胞的信号传导、分化和表观遗传重塑 | Golec, D. P. | N/A | A PI3Kδ-Foxo1-FasL signaling amplification loop rewires CD4+ T helper cell signaling, differentiation and epigenetic remodeling | |
| 灵活的、适用于生产规模的、在台式测序仪上进行的人类全基因组测序 | Green, K. | N/A | FLEXIBLE, PRODUCTION-SCALE, HUMAN WHOLE GENOME SEQUENCING ON A BENCHTOP SEQUENCER | |
| 绘制人类结肠肠内分泌细胞所显示的可成药靶点 | Lei, Y. | N/A | Mapping the druggable targets displayed by human colonic enteroendocrine cells | |
| 竞争、降水和温度塑造了miombo林冠异速生长律偏离缩放定律的形态 | Yambayamba, A. M. | N/A | Competition, precipitation and temperature shape deviations from scaling laws in the crown allometries of miombo woodlands | |
| 按蚊幼虫在水生生态系统中的营养相互作用：一种宏基因组学方法 | Karikari, A. S. | N/A | Trophic Interactions of Anopheles Gambiae Mosquito Larvae in Aquatic Ecosystem: A Metagenomics Approach | |
| 从图分析中得出的功能性重要残基：协同进化动态耦合 | Xu, M. | N/A | Functionally Important Residues from Graph Analysis of Coevolved Dynamic couplings | |
| 栽培啤酒花（Humulus lupulus L.）的进化历史及其根际微生物群落组成 | McElwee-Adame, A. | N/A | Evolutionary history and rhizosphere microbial community composition in domesticated hops (Humulus lupulus L.) | |
| 黑腹果蝇利用核结构来招募剂量补偿机制。 | Sneideman, M. P. L. | N/A | Drosophila melanogaster employs nuclear architecture for recruitment of dosage compensation | |
| 组蛋白变体H2BE调控活动依赖性基因表达及稳态缩放 | Feierman, E. R. | N/A | Histone variant H2BE controls activity-dependent gene expression and homeostatic scaling | |
| 通过建模基因型与环境互作进行花生产量的基因组预测 | Lubanga, N. | N/A | Genomic prediction by modelling genotype by environment interaction for yield in groundnut | |
| 核苷酸自组装的病理生理学意义：腺嘌呤衍生核苷酸在疾病机制中的聚集 | Dave, R. | N/A | Pathophysiological Implications of Nucleotide Self-Assembly: Adenine-Derived Nucleotides Aggregation in Disease Mechanisms | |
| 多层次牙型多样性的整合将鲨鱼宏观进化模式与生态策略联系起来。 | Zimm, R. | N/A | Integration of multi-level dental diversity links macro-evolutionary patterns to ecological strategies across sharks. | |
| 早期区域淋巴结激活可驱动祖先多样性人群中的流感疫苗反应 | Siu, J. H. | N/A | Early regional lymph node activation drives influenza vaccine responses in an ancestrally diverse cohort | |
| PIPENN-EMB：集成网络与蛋白质嵌入超越同源性推广蛋白质界面预测 | Thomas, D. P. G. | N/A | PIPENN-EMB: ensemble net and protein embeddings generalise protein interface prediction beyond homology | |
| 在非靶向代谢组学中，是否进行缺失值填补——这就是组成性问题 | Krutkin, D. D. | N/A | To impute or not to impute in untargeted metabolomics - that is the compositional question | |
| 癌症突变互斥性的贝叶斯建模 | Czyz, P. | N/A | Bayesian modeling of mutual exclusivity in cancer mutations | |
| PSTP：通过迁移学习和注意力机制解码蛋白质相分离的潜在序列语法 | Feng, M. | N/A | PSTP: Decoding Latent Sequence Grammar through Transfer Learning and Attention for Protein Phase Separation | |
| 生成低密度最小化器 | Golan, S. | N/A | Generating low-density minimizers | |
| 通过多模态深度学习预测细菌蛋白质功能 | Muzio, G. | N/A | Bacterial protein function prediction via multimodal deep learning | |
| 通过链统计提高泛基因组分类准确性 | Brown, N. K. | N/A | Improved pangenomic classification accuracy with chain statistics | |
| 缺氧诱导胰腺腺癌（PDAC）细胞系细胞表面的广泛蛋白质和蛋白水解重塑 | Lui, I. | N/A | Hypoxia induces extensive protein and proteolytic remodeling of the cell surface in pancreatic adenocarcinoma (PDAC) cell lines | |
| 靶向PTP4A3的过度表达可增强HGSOC细胞对化疗药物的敏感性。 | Lopez-Garza, A. | N/A | Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs. | |
| # BioRxiv 2024-11-01 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 在没有内侧前额叶皮层的情况下，行为的认知控制和海马信息处理 | Park, E. | N/A | Cognitive control of behavior and hippocampal information processing without medial prefrontal cortex | |
| 硬皮病亚型中独特的T细胞染色质景观 | Dou, D. R. | N/A | Distinct T cell chromatin landscapes in scleroderma subtypes | |
| 利用全基因组谱系估计扩散速率并定位遗传祖先 | Osmond, M. | N/A | Estimating dispersal rates and locating genetic ancestors with genome-wide genealogies | |
| 个体在体验多样性方面的差异塑造了事件分割的粒度。 | Hodgetts, C. J. | N/A | Individual differences in experiential diversity shape event segmentation granularity | |
| 光环：单细胞多组学数据的层次因果建模 | Mao, H. | N/A | HALO: Hierarchical Causal Modeling for Single Cell Multi-Omics Data | |
| 人类线粒体基因组编码一种干扰素应答的宿主防御肽 | Rice, M. C. | N/A | The Human Mitochondrial Genome Encodes for an Interferon-Responsive Host Defense Peptide | |
| 利用Renoir绘制空间配体-靶标活性图 | Rao, N. | N/A | Charting spatial ligand-target activity using Renoir | |
| 柳雷鸟种群的长期趋势与短期动态 | Willebrand, T. | N/A | Long term trend and short-term dynamics of a willow grouse population | |
| 磷脂酰肌醇和小热休克蛋白对NRF2的调控 | Chen, C. | N/A | Regulation of NRF2 by Phosphoinositides and Small Heat Shock Proteins | |
| 罕见的neurexin-1杂合缺失的表型复杂性 | Fernando, M. B. | N/A | Phenotypic complexities of rare heterozygous neurexin-1 deletions | |
| 中介亚基Med4在乳腺癌中强制执行转移性休眠 | Bae, S.-Y. | N/A | Mediator Subunit Med4 Enforces Metastatic Dormancy in Breast Cancer | |
| 单细胞转录组图谱揭示了急性髓系白血病中异常分化的遗传和非遗传决定因素 | Zeng, A. G. X. | N/A | Single-cell transcriptional mapping reveals genetic and non-genetic determinants of aberrant differentiation in AML | |
| 高分辨率分子动力学模拟：丙酮酸激酶肌肉同工酶1和2（PKM1/2） | Delobelle, Q. | N/A | High-resolution Molecular Dynamics Simulations of the Pyruvate Kinase Muscle Isoform 1 and 2 (PKM1/2) | |
| 一种用于建模蛋白质液-液相分离的变分图划分方法 | Wang, G. | N/A | A Variational Graph Partitioning Approach to Modeling Protein Liquid-liquid Phase Separation | |
| 事件分割的神经基础：环境中的稳定特征通过神经状态得以反映 | Oetringer, D. | N/A | The Neural Basis of Event Segmentation:Stable Features in the Environment areReflected by Neural States | |
| 通过双功能HSV载体治疗性疫苗清除慢性SIV感染猕猴中的病毒潜伏期 | Wen, Z. | N/A | Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques | |
| 抑制间接通路活性导致在帕金森病冲动控制障碍小鼠模型中出现异常决策行为 | Zhuang, X. | N/A | Inhibition of Indirect Pathway Activity Causes Abnormal Decision-Making In a Mouse Model of Impulse Control Disorder in Parkinson's Disease | |
| 自动浮游生物监测表明，微型浮游动物和温度在预测浮游植物大小类群的动态变化中起着关键作用。 | Merkli, S. | N/A | Automated plankton monitoring suggests a key role of microzooplankton and temperature for predicting dynamics of phytoplankton size classes | |
| 分子洞察：hERG激活剂对严重LQT2突变体的救援机制研究。 | Kumawat, A. | N/A | Molecular Insights into the Rescue Mechanism of an hERG Activator Against Severe LQT2 Mutations. | |
| 药物基因组学合成致死筛选揭示了NF1相关肿瘤的潜在脆弱性和新的治疗策略 | Williams, K. B. | N/A | Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors | |
| 微切割肿瘤立方体：一种保留复杂肿瘤微环境的微尺度癌症模型，适用于大规模测试 | Horowitz, L. F. | N/A | Microdissected tumor cuboids: a microscale cancer model for large-scale testing that retains a complex tumor microenvironment | |
| 在发病率高的地区，持续的跨物种传播系统主导了产志贺毒素大肠杆菌O157:H7的流行病学：一项基因组流行病学研究 | Tarr, G. A. M. | N/A | Persistent cross-species transmission systems dominate Shiga toxin-producing Escherichia coli O157:H7 epidemiology in a high incidence region: a genomic epidemiology study | |
| 串联重复蛋白为工程生物分子凝聚体引入了可调的特性。 | Ng, T. L. C. | N/A | Tandem-repeat proteins introduce tuneable properties to engineered biomolecular condensates | |
| 人类在短暂先天视觉剥夺后视觉皮层兴奋/抑制比率的改变 | Pant, R. | N/A | Altered visual cortex excitatory/inhibitory ratio following transient congenital visual deprivation in humans | |
| 筛选大猩猩博物馆标本中的DNA病毒 | Haemmerle, M. | N/A | Screening great ape museum specimens for DNA viruses | |
| 使用基于Shapley值的特征子集选择方法识别区分旁系同源蛋白的关键氨基酸类型 | Machingal, P. | N/A | Identifying key amino acid types that distinguish paralogous proteins using Shapley value based feature subset selection | |
| LETSmix：一种空间感知且基于学习的领域自适应方法，用于空间转录组学中的细胞类型反卷积 | Zhan, Y. | N/A | LETSmix: a spatially informed and learning-based domain adaptation method for cell-type deconvolution in spatial transcriptomics | |
| 前额叶5α-还原酶2介导雄性特异的急性应激反应 | Cadeddu, R. | N/A | Prefrontal 5α-reductase 2 mediates male-specific acute stress response | |
| 一种新型进食机制：太阳鸟通过舌内吸吮的方式饮用花蜜 | Cuban, D. | N/A | A novel feeding mechanism: Sunbirds drink nectar via intralingual suction | |
| 使用可穿戴、免手持系统对体外病原菌中卟啉特异性荧光进行成像 | Sun, J. | N/A | Imaging of porphyrin-specific fluorescence in pathogenic bacteria in vitro using a wearable, hands-free system | |
| 使用可解释的非结构化元数据建模对公开可用的样本和研究进行标注 | Yuan, H. | N/A | Annotating publicly-available samples and studies using interpretable modeling of unstructured metadata | |
| 水网络中的熵变促进蛋白质变性 | Wang, Y. | N/A | Entropy Changes in Water Networks Promote Protein Denaturation | |
| 功能性适应的大脑结构基集：一种动态融合方法 | Duda, M. | N/A | Functionally Adaptive Structural Basis Sets of the Brain: A Dynamic Fusion Approach | |
| 前额叶皮层和腹侧海马核伏隔核输入的奖励整合协同调节参与度 | Iyer, E. S. | N/A | Reward integration in prefrontal-cortical and ventral-hippocampal nucleus accumbens inputs cooperatively modulates engagement | |
| 哈茨木霉T22诱导根瘤菌和类黄酮驱动的共生关系，促进豌豆对缺铁的耐受性。 | Thapa, A. | N/A | Trichoderma afroharzianum T22 induces rhizobia and flavonoid-driven symbiosis to promote iron deficiency tolerance in garden pea | |
| 在成年功能连接网络中，大脑区域的一个子集在早期发育过程中表现出高度的可靠性。 | Tu, J. C. | N/A | A subset of brain regions within adult functional connectivity networks demonstrate high reliability across early development | |
| plectin介导的细胞骨架串扰作为抑制肝细胞癌生长和转移的靶点。 | Outla, Z. | N/A | Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis. | |
| 开发一种免疫分析方法用于检测和诊断由产甲烷古菌引起的微生物诱导腐蚀 | Lahme, S. | N/A | Development of an immunoassay for the detection and diagnosis of microbially-influenced corrosion caused by methanogenic Archaea | |
| 使用深度学习在冷冻电镜和X射线图中识别配体 | Karolczak, J. | N/A | Ligand Identification in CryoEM and X-ray Maps Using Deep Learning | |
| 生物学约束的脉冲神经网络用于脊髓损伤后运动功能恢复的神经调节 | Chia, R. | N/A | Biologically-Constrained Spiking Neural Network for Neuromodulation in Locomotor Recovery after Spinal Cord Injury | |
| 结合骑行性高温与紫锥菊苷对胰腺癌细胞PANC-1产生协同治疗效果 | Chen, W.-T. | N/A | Combination of cycling hyperthermia and Echinacoside creates synergistic curing effect on pancreatic cancer PANC-1 cells | |
| 针对牛繁殖失败相关病原体的靶向综合下一代测序面板，用于同时检测病原体。 | Periyasamy, D. | N/A | Targeted syndromic next-generation sequencing panel for simultaneous detection of pathogens associated with bovine reproductive failure | |
| 不仅仅是果香：番荔枝科植物的花部生物学、香气和光谱反射率 | Liu, M.-F. | N/A | More than fruity scents: floral biology, scent and spectral reflectance of Annonaceae species | |
| 使用HarmoDecon缓解空间分辨转录组学中细胞类型反卷积的多尺度偏差 | Wang, Z. | N/A | Mitigation of multi-scale biases in cell-type deconvolution for spatially resolved transcriptomics using HarmoDecon | |
| 纹状体侧向抑制调节左旋多巴诱发运动障碍小鼠模型中的动作选择 | Twedell, E. L. | N/A | Striatal lateral inhibition regulates action selection in a mouse model of levodopa-induced dyskinesia | |
| NAD的二核苷酸结构使其能够在矿物表面上进行特定的还原作用。 | Pereira, D. P. H. | N/A | The dinucleotide structure of NAD enables specific reduction on mineral surfaces | |
| 阴离子脂质对阴离子交换蛋白1（AE1）构象转变能量景观的影响 | Chen, T. | N/A | Impact of anionic lipids on the energy landscape of conformational transition in anion exchanger 1 (AE1) | |
| 鉴定和表征从淡水斑马贻贝（Dreissena bugensis）中提取的一种湿粘蛋白 | Obille, A. R. | N/A | Identification and characterization of a wet adhesive protein extracted from Dreissena bugensis, the freshwater quagga mussel | |
| 丝裂霉素C与低剂量甲硝唑联合使用对艰难梭菌感染及其复发具有协同预防作用 | Gong, J.-J. | N/A | Combination of mitomycin C and low-dose metronidazole synergistically against Clostridioides difficile infection and recurrence prevention | |
| 研究Huntingtin蛋白的Nt17结构域的曲率感应 | Nanajkar, N. | N/A | Investigating curvature sensing by the Nt17 domain of Huntingtin protein | |
| TFAM作为UVC诱导的线粒体DNA损伤的传感器 | King, D. E. | N/A | TFAM as a sensor of UVC-induced mitochondrial DNA damage | |
| 生长素-水杨酸跷跷板调控植物生长与食草动物防御之间的年龄依赖性平衡 | Han, W.-H. | N/A | Auxin-salicylic acid seesaw regulates the age-dependent balance between plant growth and herbivore defense | |
| ProteinWeaver：一个用于可视化本体注释蛋白质网络的网络工具 | Anderson, O. F. | N/A | ProteinWeaver: A Webtool to Visualize Ontology-Annotated Protein Networks | |
| Neuroligin 3 突显了果蝇社交距离中的性别二态性电路 | Robinson, J. W. | N/A | Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing | |
| CFC-seq：全长加帽RNA的鉴定揭示增强子来源的转录 | Yip, C. W. | N/A | CFC-seq: identification of full-length capped RNAs unveil enhancer-derived transcription | |
| TIPP3 和 TIPP3-fast：改进的宏基因组丰度分析 | Shen, C. | N/A | TIPP3 and TIPP3-fast: Improved Abundance Profiling in Metagenomics | |
| 小鼠、猕猴和人类中一致的单神经元时间尺度层次结构 | Zeisler, Z. R. | N/A | Consistent hierarchies of single-neuron timescales in mice, macaques and humans | |
| 基底神经节和小脑回路在运动学习期间丘脑的整合作用 | Roth, R. H. | N/A | Thalamic integration of basal ganglia and cerebellar circuits during motor learning | |
| 在假定的敏感期，青少年的前额叶皮层比成年人表现出更强的群体水平信息编码能力。 | Klinger, M. | N/A | The adolescent frontal cortex shows stronger population-level encoding of information than the adult during a putative sensitive period | |
| 产前应激通过损害胎盘的糖皮质激素屏障功能，增加了后代皮质酮的水平。 | Liu, C. | N/A | Prenatal stress increases corticosterone levels in offspring by impairing placental glucocorticoid barrier function | |
| 预测的受限可及区域标记调控元件和因果变异 | Tomizuka, K. | N/A | Predicted constrained accessible regions mark regulatory elements and causal variants | |
| 齿状回去甲肾上腺素渐增促进厌恶情境加工 | Zhang, E. T. | N/A | Dentate Gyrus Norepinephrine Ramping Facilitates Aversive Contextual Processing | |
| 新环境暴露驱动了海马体中时间定义和区域特异性的染色质可及性和基因表达变化 | Duffy, E. E. | N/A | Novel environment exposure drives temporally defined and region-specific chromatin accessibility and gene expression changes in the hippocampus | |
| 三重标记通过三色单分子FRET解析GPCR的中间状态 | Bonhomme, L. | N/A | Triple labeling resolves a GPCR intermediate state by 3-color single molecule FRET | |
| 内在无序蛋白质内部基于电荷的瞬时相互作用的结构和功能相关性 | Wohl, S. | N/A | Structural and Functional Relevance of Charge Based Transient Interactions inside Intrinsically Disordered Proteins | |
| H1和H3血凝素跨膜结构域以不同方式参与膜融合 | Borkowska, P. | N/A | Transmembrane domains of H1 and H3 hemagglutinin contribute to membrane fusion in a different manner | |
| 从分子动力学模拟中学习Gα蛋白的变构相互作用 | Yu, Y. | N/A | Learning allosteric interactions in Gα proteins from molecular dynamics simulations | |
| COCOMO2：一种用于相互作用的折叠和无序蛋白质的粗粒度模型 | Jussupow, A. | N/A | COCOMO2: A coarse-grained model for interacting folded and disordered proteins | |
| 通过质谱和反相蛋白阵列分析的全蛋白质组、磷酸蛋白质组和糖蛋白质组的泛癌细胞系全景图 | Shi, W. | N/A | The Whole Proteome, Phosphoproteome, and Glycoproteome Landscape of Pan-Cancer Cell Lines Profiled by Mass Spectrometry and Reverse Phase Protein Array | |
| 一种针对RSV和hMPV融合糖蛋白抗原位点V的中和性和保护性人类抗体 | Abu-Shmais, A. A. | N/A | A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein | |
| mGluR6先天性静止性夜盲突变体的糖基化缺陷及与ELFN1的结合异常 | Pindwarawala, M. | N/A | Defective glycosylation and ELFN1 binding of mGluR6 congenital stationary night blindness mutants | |
| 代谢调控糖基化形式以建立糖基依赖的蛋白质相互作用网络 | Liu, X. | N/A | Metabolic Control of Glycosylation Forms for Establishing Glycan-Dependent Protein Interaction Networks | |
| 通过引导AlphaFold2利用距离分布建模蛋白质构象。应用于双电子电子共振（DEER）光谱学。 | Wu, T. | N/A | Modeling Protein Conformations by Guiding AlphaFold2 with Distance Distributions. Application to Double Electron Electron Resonance (DEER) Spectroscopy. | |
| 结构环境调节α-突触核蛋白内在无序氨基末端的构象集合 | Dumarieh, R. | N/A | Structural context modulates the conformational ensemble of the intrinsically disordered amino terminus of α-synuclein | |
| 在认知需求增加时，齿状回的局部活动会增强。 | Castillon, C. | N/A | Subregional activity in the dentate gyrus is amplified during elevated cognitive demands | |
| 细菌中一种非常规G蛋白复合物对细胞极性的调控 | Mignot, T. | N/A | Cell polarity control by an unconventional G-protein complex in bacteria | |
| 巴基斯坦旁遮普省生产的面包废料对罗非鱼幼鱼的表观消化率和营养表现 | Hussain, S. S. | N/A | Apparent digestibility and nutritional performance of bakery waste produced in Punjab Pakistan for Labeo rohita fingerlings | |
| 脂质运输Mla Pqi嵌合系统对布鲁氏菌在巨噬细胞中的生存至关重要 | Lannoy, A. | N/A | A lipid transport Mla Pqi Chimeric system is essential for Brucella abortus survival in macrophages | |
| 全基因组研究大肠杆菌外膜蛋白家族在马赛克进化中的情况 | Cao, X. | N/A | Genome-wide investigation of outer membrane protein families under mosaic evolution in Escherichia coli | |
| 合成磁性纳米颗粒的生物功能化涂层能够实现对细胞内蛋白质功能的磁遗传控制。 | Kappen, M. | N/A | Biofunctional coating of synthetic magnetic nanoparticles enables magnetogenetic control of protein functions inside cells | |
| cryoMDM：基于噪声冷冻电镜单颗粒图像的分子模拟驱动结构匹配方法，用于估计多种原子三维模型。 | Tokuhisa, A. | N/A | cryoMDM; Molecular simulation Driven structural Matching Approach to Estimate Variety of Atomic Three-dimensional Model Based on Noisy cryoEM Single Particle Images. | |
| 全原子模拟阐明了RNA与膜相互作用的分子机制 | Di Marco, S. | N/A | All-atom simulations elucidate the molecular mechanismunderlying RNA-membrane interactions | |
| 系统性抑制从头嘌呤生物合成通过增加产热和减少食物摄入，防止体重增加并改善代谢健康。 | Myers, J. W. | N/A | Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake | |
| 软X射线断层扫描的自动分割：在酵母全细胞定量成像中实现高通量下亚微米分辨率的天然细胞结构 | Chen, J.-H. F. | N/A | Automated segmentation of soft X-ray tomography: native cellular structure with sub-micron resolution at high throughput for whole-cell quantitative imaging in yeast | |
| 直接胰岛素分泌发生在具有最佳ELKS含量的精确皮层区域，这些区域缺乏微管结构。 | Fye, M. A. | N/A | Directed insulin secretion occurs at precise cortical regions with optimal ELKS content that are devoid of microtubules | |
| 有机组织结构是预测气道模型中全氟碳化合物暴露结果的必要条件。 | Liu, S. W. | N/A | Organotypic tissue architecture is a requisite for predictive outcomes of perfluorocarbon exposure in airway models | |
| 来自组织微环境的Tenascin-C通过Annexin A2促进肌肉干细胞自我更新。 | Loreti, M. | N/A | Tenascin-C from the tissue microenvironment promotes muscle stem cell self-renewal through Annexin A2 | |
| 改变肾脏血管模式可减轻缺血性肾损伤，并限制与衰老相关的血管损失 | McLarnon, S. R. | N/A | Altered renal vascular patterning reduces ischemic kidney injury and limits vascular loss associated with aging | |
| 最佳竞争者：互利共生者（如传粉者）的吸引力与选择之间的平衡推动了促进作用，并可能促进作物传粉。 | Dornhaus, A. | N/A | Optimal competitors: the balance of attraction and choices of mutualists, like pollinators, drives facilitation and may promote crop pollination | |
| 通过微调蛋白质和小分子语言模型学习结合亲和力 | Gorantla, R. | N/A | Learning Binding Affinities via Fine-tuning of Protein and Ligand Language Models | |
| 波形蛋白与nesprin-3的分子连接通过细胞几何约束增强了细胞核的变形 | Swoger, M. | N/A | Vimentin molecular linkages with nesprin-3 enhance nuclear deformation by cell geometric constraints | |
| 单个细胞能够感知分等级的刺激 | Kramar, M. | N/A | Single cells can resolve graded stimuli | |
| 通过K函数分析揭示的细胞竞争的空间和时间特征 | Day, N. | N/A | Spatial and temporal signatures of cell competition revealed by K-function analysis | |
| 壳聚糖纳米胶囊与非洲鸭脚木提取物对Wistar大鼠的免疫系统具有调节作用 | Nyuyfoni, G. F. | N/A | Chitosan nanocapsules with Alstonia boonei extract modulate the immune system in Wistar rats | |
| 纳米生理学方法揭示了斑马鱼视网膜双极带状突触中钙微域的多样性 | Rameshkumar, N. | N/A | Nanophysiology Approach Revealed Diversity in Calcium Microdomains in Zebrafish Retinal Bipolar Ribbon Synapses | |
| 铜宫内节育器对减少母马子宫感染的测试：一项初步研究 | Gradil, C. | N/A | The Testing of Copper Intrauterine Devices to Mitigate Uterine Infections in Mares: A Preliminary Study | |
| 用于细胞表面交叉光学和化学标记的工具 | Innes-Gold, S. | N/A | Tools for intersectional optical and chemical tagging on cell surfaces | |
| 可变剪接调节染色质互作组及RIF1 C端结构域的相分离 | Koo, A. S.-H. | N/A | Alternative splicing modulates chromatin interactome and phase separation of the RIF1 C-terminal domain | |
| LARP4的短保守区域-2与核糖体相关蛋白RACK1相互作用，并促进翻译过程。 | Ranjan, A. | N/A | The short conserved region-2 of LARP4 interacts with ribosome-associated RACK1 and promotes translation | |
| 复制体通过黏连蛋白环的过程 | Glaser, S. | N/A | Replisome passage through the cohesin ring | |
| 一种新型微型丝状噬菌体作为基因递送载体靶向哺乳动物细胞 | Wong, S. | N/A | A novel miniaturized filamentous phagemid as a gene delivery vehicle to target mammalian cells | |
| 链球菌噬菌体基因组揭示了广泛的多样性、新的分类学见解以及源自内溶素的全新抗菌肽 | Mondal, S. I. | N/A | Streptococcus Phage Genomes Reveal Extensive Diversity, New Taxonomic Insights, and Novel Endolysin-Derived Antimicrobial Peptides | |
| 新见解：洛蒙丝孢菌（Lomentospora prolificans）黑色素结构 | Liporagi Lopes, L. | N/A | New Insights Into The Melanin Structure Of Lomentospora prolificans | |
| EasyAb：一种基于抗体的高通量工作流程，用于与质谱联用的PTM肽富集方法 | Jayavelu, A. K. | N/A | EasyAb: A High-Throughput Workflow for Antibody-Based PTM Peptide Enrichment Method Coupled to Mass Spectrometry | |
| 高吞吐量活细胞单细胞蛋白质组学 | Karagach, S. | N/A | High throughput single-cell proteomics of in-vivo cells | |
| 由脂质过氧化产生的N-醛基修饰磷脂酰乙醇胺是N-酰基磷脂酰乙醇胺磷脂酶D的强效底物。 | Fadaei, R. | N/A | N-Aldehyde-Modified Phosphatidylethanolamines generated by lipid peroxidation are robust substrates of N-Acyl Phosphatidylethanolamine Phospholipase D | |
| 非经典GPCR信号转导在Hedgehog通路中的结构机制 | Steiner, W. P. | N/A | A Structural Mechanism for Noncanonical GPCRSignal Transduction in the Hedgehog Pathway | |
| 一种定量细胞内肽结合分析揭示了短线性基序的识别决定因素及其上下文依赖性 | Subbanna, M. S. | N/A | A quantitative intracellular peptide binding assay reveals recognition determinants and context dependence of short linear motifs | |
| 伪GTP酶介导的蛋白质-蛋白质相互作用的结构基础 | Wang, B. | N/A | Structural basis of pseudoGTPase-mediated protein-protein interactions | |
| 哺乳动物黑视蛋白与拮抗剂AA92593特异性相互作用的分子基础 | Obayashi, K. | N/A | Molecular basis underlying specific interaction of mammalian melanopsins with an antagonist AA92593 | |
| 通过魔角旋转核磁共振技术获得的噬菌体P22衣壳蛋白在原衣壳中的结构模型 | Guo, C. | N/A | Structural Model of Bacteriophage P22 Scaffolding Protein in a Procapsid by Magic-Angle Spinning NMR | |
| Notch信号阻断将静息神经干细胞的转录组异质性与它们的再激活途径及潜能联系起来。 | Morizet, D. | N/A | Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with their reactivation routes and potential | |
| 在物体处理过程中，反馈信号中的高阶和低阶特征具有不同的目标、动态变化和功能 | Hou, W. | N/A | Differential destinations, dynamics, and functions of high- and low-order features in the feedback signal during object processing | |
| 通过通信子空间在大规模新皮层模型中进行认知网络交互 | Pereira-Obilinovic, U. | N/A | Cognitive networks interactions through communication subspaces in large-scale models of the neocortex | |
| 病毒载体介导的SLC9A6基因替代减少了Christianson综合征摇晃大鼠模型中的小脑功能障碍 | Anderson, C. J. | N/A | Viral vector-mediated SLC9A6 gene replacement reduces cerebellar dysfunction in the shaker rat model of Christianson syndrome | |
| 大脑功能连接，而非神经解剖结构，捕捉到了青春期前性别与性别的相互关系。 | Metoki, A. | N/A | Brain functional connectivity, but not neuroanatomy, captures the interrelationship between sex and gender in preadolescents | |
| 同时对小鼠皮层活动进行介观测量与操控 | Matveev, P. | N/A | Simultaneous mesoscopic measurement and manipulation of mouse cortical activity | |
| 顺序规划的整合 | Vikbladh, O. M. | N/A | Consolidation of Sequential Planning | |
| 在SH-SY5Y细胞中DJ-1缺陷揭示了涉及神经功能和疾病的基因和通路网络失调 | Gock, N. | N/A | DJ-1 deficiency in SH-SY5Y cells reveals dysregulated networks of genes and pathways involved in neuronal function and disease | |
| 线粒体NADK2依赖的NADPH调控人类神经元中Tau寡聚体的摄取 | Pardo, E. C. | N/A | Mitochondrial NADK2-dependent NADPH controls Tau oligomer uptake in human neurons | |
| 伦敦出租车司机利用区域边界来优化路线选择，并在三十年的时间内提升他们的导航技能。 | Gahnstrom, C. J. | N/A | London taxi drivers leverage regional boundaries to optimise route choices and improve their navigation skill across three decades | |
| DJ-1 介导帕金森病星形胶质细胞和胶质母细胞瘤细胞中代谢和免疫反应的调控 | Mencke, P. | N/A | DJ-1 mediates regulation of metabolism and immune response in Parkinsons disease astrocytes and Glioblastoma cells | |
| 急性及早期应激轴调节在关节疾病中能永久性地减轻疼痛和情感共病 | Hestehave, S. | N/A | Acute and early stress axis modulation in joint disease permanently reduces pain and emotional comorbidities | |
| 两种方法和时间尺度表明，水中珊瑚疾病治疗并未促进抗生素抗性的发展。 | Neely, K. L. | N/A | Two methodologies and timescales show no promotion of antibiotic resistance from in-water coral disease treatments | |
| 适应性实验室进化产生的耐粘菌素铜绿假单胞菌菌株中，PmrB传感器激酶的适应性权衡及新错义突变的发现 | Padhy, I. | N/A | Fitness trade-off and the discovery of a novel missense mutation in the PmrB sensor kinase of a colistin-resistant Pseudomonas aeruginosa strain developed by adaptive laboratory evolution | |
| 新型共生生物揭示阿米巴原虫是环境衣原体的重要宿主 | Liu, F. | N/A | Novel symbionts reveal amoebae as significant hosts for environmental chlamydiae | |
| 利用基于活性的蛋白质谱分析筛选化疗诱导外周神经病变大鼠模型中的潜在生物标志物 | Miao, H. | N/A | Screening of potential biomarkers using activity-based protein profiling in a rat model of chemotherapy-induced peripheral neuropathy | |
| 季风影响下的两条印度城市河流中抗生素抗性的驱动因素，这些河流接收未经处理的废水 | Bagra, K. | N/A | Drivers of antibiotic resistance in two monsoon-impacted Indian urban rivers receiving untreated wastewater | |
| 小梁网单细胞分析鉴定出青光眼模型中的线粒体功能障碍，该功能障碍可通过维生素B3治疗得到保护 | Tolman, N. | N/A | Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment | |
| 利用差示扫描量热法数据对两态蛋白质转变的标准拟合技术的显式推导 | Priklopil, T. | N/A | Explicit derivation of the standard fitting technique for two-state protein transitions using differential scanning calorimetry data | |
| 动脉平滑肌细胞中自噬介质Parkin的缺乏会加剧腹主动脉瘤的形成。 | Wang, H. | N/A | Deficiency of mitophagy mediator Parkin in aortic smooth muscle cells exacerbates abdominal aortic aneurysm | |
| 一种基于大肠杆菌的平台，用于环状病毒载体的生产和组装 | Prakash, R. | N/A | An E. coli-based platform for the production and assembly of anellovirus vectors | |
| 心脏管形态发生受MEF2C调控的节段特异性基因调控网络的调节。 | Muncie-Vasic, J. M. | N/A | Heart tube morphogenesis is regulated by segment-specific gene regulatory networks controlled by MEF2C | |
| 啮齿动物牙齿发育的多模态表征 | Jiang, Y. | N/A | Multi-modal characterization of rodent tooth development | |
| 鸟类前肠的延长需要内在和外在细胞行为的协调。 | Powell, O. | N/A | Elongation of the nascent avian foregut requires coordination of intrinsic and extrinsic cell behaviors | |
| TFAP2C是子宫内滋养层细胞侵袭和深部血绒毛膜胎盘形成的关键调节因子。 | Dominguez, E. M. | N/A | TFAP2C is a key regulator of intrauterine trophoblast cell invasion and deep hemochorial placentation | |
| 稀疏动物社会网络分析 | Mylne, H. K. | N/A | Analysis of sparse animal social networks | |
| 通过胞外囊泡非经典分泌自噬相关蛋白VMP1作为胰腺细胞损伤潜在生物标志物 | Tadic, M. S. | N/A | UNCONVENTIONAL SECRETION OF THE AUTOPHAGY-RELATED PROTEIN VMP1 VIA EXTRACELLULAR VESICLES AS A POTENTIAL BIOMARKER FOR PANCREATIC CELL INJURY | |
| BamE的N端延伸区域协调BamA的β-桶域与BamD之间的相互作用，以实现高效组装。 | Maruno, Y. | N/A | The N-terminal extension region of BamE coordinates interaction between the β-barrel domain of BamA and BamD for efficient assembly | |
| 基于去稳定剂的细菌微隔室壳体外快速组装与装载方法 | Range, K. L. | N/A | A chaotrope-based approach for rapid in vitro assembly and loading of bacterial microcompartment shells | |
| 腹侧被盖区与人类的风险厌恶行为之间的功能耦合 | Lin, W. | N/A | Habenula-ventral tegmental area functional coupling and risk-aversion in humans | |
| 灵长类视网膜输出中的功能多样性 | Kling, A. | N/A | Functional diversity in the output of the primate retina | |
| 星形胶质细胞控制人类皮层网络中的UP状态和慢振荡周期性 | Crowe, J. A. | N/A | Astrocytes control UP state and slow oscillation periodicity in human cortical networks | |
| 线粒体应激通过蛋白水解激活PKCδ和Lamin B1磷酸化，在神经元细胞中解构核结构：与年龄相关性神经退行性疾病发病机制的关联 | Charli, A. | N/A | Mitochondrial Stress Disassembles Nuclear Architecture through Proteolytic Activation of PKCδ and Lamin B1 Phosphorylation in Neuronal Cells: Implications for Pathogenesis of Age-related Neurodegenerative Diseases | |
| 从果蝇连接组到精确的环吸引子动力学 | Biswas, T. | N/A | From the fly connectome to exact ring attractor dynamics | |
| 雄性和雌性大鼠在精神兴奋剂自我给药行为方面的最显著差异与生物性别无关。 | Showell, B. H. | N/A | The most significant differences between male and female rats regarding psychostimulant self-administration behavior are unrelated to biological sex | |
| 使用结合通道停用策略和可变数量动态聚焦通道的成人耳蜗植入者的噪音中言语表现 | Wohlbauer, D. M. | N/A | Speech in noise performance in adults with cochlear implants using a combined channel deactivation strategy with a variable number of dynamic focused channels | |
| 电休克疗法在发作后产生了一股隐秘的浪潮 | Rosenthal, Z. | N/A | Electroconvulsive therapy generates a hidden wave after seizure | |
| 偏倚校正元分析克服了小脑忽视，以优化小脑行为地形图 | Magielse, N. | N/A | Bias-accounting meta-analyses overcome cerebellar neglect to refine the cerebellar behavioral topography | |
| 侧化的结状神经节基因表达暗示了胆囊收缩素受体在体内奖励信号传导中的作用 | Welch, H. F. | N/A | Lateralized nodose ganglia gene expression implicates cholecystokinin receptors in interoceptive reward signaling | |
| 在长期增强过程中，突触前囊泡簇从紧密组织转变为松散组织。 | Garcia, G. C. | N/A | The presynaptic vesicle cluster transitions from a compact to loose organization during long-term potentiation | |
| Tcf4缺乏导致小鼠反复发作癫痫 | Craciun, L. | N/A | Tcf4 Deficiency Causes Recurrent Seizures in Mice | |
| 每日电场治疗可改善大鼠胸椎挫伤脊髓损伤后的功能结果 | Harland, B. | N/A | Daily electric field treatment improves functional outcomes after thoracic contusion spinal cord injury in rats | |
| 神经同步性对于语音理解来说是“足够好”的。 | Rafferty, M. B. | N/A | Neural synchrony is "good enough" for speech comprehension | |
| 背景很重要：整合NMDA受体功能障碍揭示了在小鼠模型中携带人类患者GluN1变异的有效癫痫治疗方法 | Venkatesan, S. | N/A | Context matters: Integrative NMDA receptor dysfunction reveals effective seizure treatment in mice with a human patient GluN1 variant | |
| 高效采样PROTAC诱导的三元复合物 | Zhao, H. | N/A | Efficient Sampling of PROTAC-Induced Ternary Complexes | |
| 母体Med12保护滋养层多能性和胎盘发育 | Halstead, M. M. | N/A | Maternal Med12 safeguards trophoblast pluripotency and placental development | |
| 钙瞬变调控多纤毛细胞在爪蟾皮肤发育中的上皮整合。 | Christodoulou, N. | N/A | Calcium transients regulate epithelial integration of multiciliated cells during Xenopus skin development. | |
| RNA结合蛋白Khdrbs1通过剪接调控造血干细胞和祖细胞的出现 | Karp, I. | N/A | RNA Binding Protein Khdrbs1 Regulates Hematopoietic Stem and Progenitor Cell Emergence via Splicing | |
| 小蜂Nasonia vitripennis中异常巨大的种系决定因子的结构与组成 | Kemph, A. | N/A | Novel structure and composition of the unusually large germline determinant of the wasp Nasonia vitripennis | |
| 简化胎鼠影像中的不对称量化：基于专家指导的半自动化流程 | Rolfe, S. M. | N/A | Streamlining Asymmetry Quantification in Fetal Mouse Imaging: A Semi-Automated Pipeline Supported by Expert Guidance | |
| 嗅觉系统中Prok2下游基因的时空调控：从发育到功能 | Kim, B.-R. | N/A | Spatiotemporal regulation by downstream genes of Prok2 in olfactory system: from development to function | |
| 宿主遗传背景而非环境对扁卷螺（Bulinus truncatus）的微生物群构成具有更大影响，扁卷螺是血吸虫属物种的中间宿主。 | Jaquet, M. J. | N/A | Evidences that host genetic background more than the environment shapes the microbiota of the snail Bulinus truncatus, an intermediate host of Schistosoma species. | |
| 鲸鱼语言模型：利用机器学习在抹香鲸的声音和行为中寻找结构与信息 | Sharma, P. | N/A | WhaleLM: Finding Structure and Information in Sperm Whale Vocalizations and Behavior with Machine Learning | |
| 通过mRNA递送对人类造血干细胞进行体内基因编辑以治疗血液疾病 | Xu, S. | N/A | In vivo genome editing of human hematopoietic stem cells for treatment of blood disorders by mRNA delivery | |
| 系统性剖析正常乳腺组织中的表观遗传年龄加速现象，揭示其与雌激素信号传导及癌症风险的关联 | Sehl, M. E. | N/A | Systematic dissection of epigenetic age acceleration in normal breast tissue reveals its link to estrogen signaling and cancer risk | |
| 抗寄生虫苯二氮卓类药物美克洛嗪对曼氏血吸虫转录表型的影响 | Henthorn, C. R. | N/A | Transcriptional phenotype of the anti-parasitic benzodiazepine meclonazepam on the blood fluke Schistosoma mansoni | |
| 全鼠肾小球纳米级光学成像、重建与空间分析 | Ali, A. | N/A | Nanoscale Optical Imaging, Reconstruction, and Spatial Analysis of Whole Mouse Glomeruli | |
| 拟议的普遍存在于超微细菌门Patescibacteriota phyl. nov.中的新属Patescibacterium danicum gen. nov., sp. nov. | Dutkiewicz, Z. | N/A | Proposal of Patescibacterium danicum gen. nov., sp. nov. in the ubiquitous ultrasmall bacterial phylum Patescibacteriota phyl. nov. | |
| 精氨酸及其代谢在TGF-β诱导的肺成纤维细胞激活中的作用 | Hamanaka, R. B. | N/A | Role of Arginine and its Metabolism in TGF-β-Induced Activation of Lung Fibroblasts | |
| 互养网络结构影响生长抑制压力下的微生物群落多样性 | Newton, D. P. | N/A | The network structure of cross-feeding impacts microbial community diversity under growth-inhibiting stresses | |
| 结合系统发育和地理数据可以高度准确地预测植物-害虫相互作用 | Hernandez-Gutierrez, E. | N/A | Combined phylogenetic and geographic data can predict plant-pest interactions with high accuracy | |
| 三萜环化酶的进化历史和现代多样性 | McShea, H. | N/A | The evolutionary history and modern diversity of triterpenoid cyclases | |
| 古代二倍体栽培棉种草棉（Gossypium herbaceum L.）和亚洲棉（G. arboreum L.）的传播模式对比 | Viot, C. R. | N/A | Contrasting dissemination patterns of diploid cultivated cotton species Gossypium herbaceum L. and G. arboreum L. in Antiquity | |
| 在宿主多样化的环境中克雷伯氏菌噬菌体的进化策略 | Ferriol-Gonzalez, C. | N/A | Evolutionary strategies of Klebsiella phages in a host-diverse environment | |
| 基因组证据表明，蝾螈中的平衡致死系统起源于一次瞬间的物种形成事件。 | France, J. M. | N/A | Genomic evidence suggests the balanced lethal system in Triturus newts originated in an instantaneous speciation event. | |
| 特质冗余和信息内容对人类系统发育推断的影响 | Raskin, L. Y. | N/A | The effects of trait redundancy and information content on hominin phylogenetic inference | |
| 入侵阿根廷蚁（Linepithema humile）的群体基因组学——尽管遗传多样性低，引入的超群体中仍存在适应性进化 | Holmberg, I. | N/A | Population Genomics of the Invasive Argentine Ant (Linepithema humile) - Adaptive Evolution in the Introduced Supercolonies Despite Low Genetic Diversity | |
| 巢寄生中的极端疲劳抗性类似于与宿主之间的乞食竞争中的消耗战 | Antonson, N. D. | N/A | Extreme fatigue-resistance in a brood parasite parallels a war of attrition in begging competition with hosts | |
| 合成USC-093及其对映体前体USC-093D在体外及叙利亚仓鼠模型中对抗腺病毒的效果比较 | Yang, J. | N/A | Synthesis of USC-093 and comparison with its promoiety enantiomer USC-093D against adenovirus in vitro and in a Syrian hamster model | |
| 吸收分子使活体小鼠的腹部和背部都变得透明 | TIE, X. | N/A | Absorbing molecules make both abdomen and back transparent in live mice | |
| PMAIP1介导的葡萄糖代谢及其对乳腺癌肿瘤微环境的影响：多组学分析与实验验证的整合 | Zhang, Y. | N/A | PMAIP1-Mediated Glucose Metabolism and its Impact on the Tumor Microenvironment in Breast Cancer: Integration of Multi-Omics Analysis and Experimental Validation | |
| 通过注意力增强的表征学习探索表型相关的单细胞 | Wu, Q. | N/A | Exploring phenotype-related single-cells through attention-enhanced representation learning | |
| TeloSearchLR：一种利用长序列读取检测新端粒重复基序的算法 | Chung, G. | N/A | TeloSearchLR: an algorithm to detect novel telomere repeat motifs using long sequencing reads | |
| FOXM1调控血小板诱导的胰腺癌细胞失巢凋亡抵抗 | Ernesti, A. | N/A | FOXM1 regulates platelet-induced anoikis resistance in pancreatic cancer cells | |
| 细菌无细胞DNA分析显示，疑似败血症的新生马驹中多种细菌共同升高 | Chen, L.-T. | N/A | Bacterial cell-free DNA profiling reveals co-elevation of multiple bacteria in newborn foals with suspected sepsis | |
| 基于微针的DNA提取实现无损种子基因型鉴定 | Li, M. | N/A | Nondestructive Seed Genotyping via Microneedle-Based DNA Extraction | |
| DANGEROUS MIX 3（一种α/β水解酶）触发植物中NLR介导的遗传不相容性的结构决定因素 | Kim, G. | N/A | Structure determinants of DANGEROUS MIX 3, an alpha/beta hydrolase, for triggering NLR-mediated genetic incompatibility in plants | |
| 基于基因的适应性和碳同化能力在不同大果栎种群间的变异 | Rea, L. M. S. | N/A | Genetically based variation in fitness and carbon assimilation among bur oak populations | |
| NuclampFISH技术能够基于核RNA表达进行细胞分选，以用于染色质分析。 | Liu, Y. | N/A | NuclampFISH enables cell sorting based on nuclear RNA expression for chromatin analysis | |
| 分享聚光灯：揭示跨物种的共同注意力动态 | Glukhova, M. | N/A | Sharing the Spotlight: Uncovering common attentional dynamics across species | |
| SenSeqNet：一种基于深度学习的蛋白质序列细胞衰老检测框架 | Jiang, H. | N/A | SenSeqNet: A Deep Learning Framework for Cellular Senescence Detection from Protein Sequences | |
| TILLCANN：一种用于大麻（Cannabis sativa）突变发现和作物改良的TILLING平台 | Duarte-Delgado, D. | N/A | TILLCANN: A TILLING platform in Cannabis sativa for mutation discovery and crop improvement | |
| # BioRxiv 2024-10-31 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 猕猴意识访问的介尺度连接组模型 | Klatzmann, U. | N/A | A MESOSCALE CONNECTOME-BASED MODEL OF CONSCIOUS ACCESS IN THE MACAQUE MONKEY | |
| 猪带绦虫幼虫阶段RT-qPCR相对表达分析中参考基因的验证 | Castaneda, D. | N/A | Validation of Reference Genes for RT-qPCR Relative Expression Analysis in Pre-Adult Stages of Taenia solium | |
| 社会蜜蜂（Bombus impatiens）中的雌性生殖是由蜂王调控的。 | Santos, P. K. F. | N/A | Gyne production is regulated by the brood in a social bee (Bombus impatiens) | |
| LoxCode 体内克隆条形码技术解析了哺乳动物胚胎外胚层对胎儿器官的贡献 | Weber, T. S. | N/A | LoxCode in vivo clonal barcoding resolves mammalian epiblast contribution to fetal organs | |
| 一种与Toll受体共同作用的神经营养因子调控多巴胺能环路中的结构可塑性 | Sun, J. | N/A | A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit | |
| 药物抑制星形胶质细胞中的转谷氨酰胺酶2有助于促进神经支持性星形胶质细胞反应表型的表达，这与组蛋白乙酰化水平的增加相关。 | Delgado, T. | N/A | Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation | |
| 复制应激诱导的ELF3上调促进了BRCA1缺陷型乳腺管腔祖细胞的肿瘤发生 | Zhou, J. | N/A | Replication stress inducing ELF3 upregulation promotes BRCA1-deficient breast tumorigenesis in luminal progenitors | |
| 克隆性造血的人血浆蛋白质组特征 | Yu, Z. | N/A | Human Plasma Proteomic Profile of Clonal Hematopoiesis | |
| 丘脑的 reuniens 核在睡眠期间促进海马与皮层之间的对话。 | Basha, D. | N/A | The reuniens nucleus of the thalamus facilitates hippocampo-cortical dialogue during sleep | |
| 神经科学中的无监督对齐：介绍用于Gromov-Wasserstein最优传输的工具箱 | Sasaki, M. | N/A | Unsupervised Alignment in Neuroscience: Introducing a Toolbox for Gromov-Wasserstein Optimal Transport | |
| 学习阶段恢复 | Halpern, D. | N/A | Study-Phase Reinstatement | |
| 确保多模态单细胞数据的对角线整合，防止模糊映射 | Zhou, H. | N/A | Securing diagonal integration of multimodal single-cell data against ambiguous mapping | |
| 人源化GM-CSF/IL-3增强人源化肝癌患者来源异种移植瘤中的肿瘤免疫浸润 | Weinfurtner, K. | N/A | Human GM-CSF/IL-3 enhance tumor immune infiltration in humanized HCC patient-derived xenografts | |
| 果蝇盐生种群中网状进化的跃变事件 | Prediger, C. | N/A | Saltational episodes of reticulate evolution in the Drosophila saltans species group | |
| 无突触蛋白在保守的Nedd4 E3泛素连接酶途径中充当底物适配器，促进轴突跨中线生长。 | Sullivan, K. G. | N/A | Commissureless acts as a substrate adapter in a conserved Nedd4 E3 ubiquitin ligase pathway to promote axon growth across the midline | |
| 通过一个可组装的计算框架探索人类决策异常中的有限理性 | Lu, Y.-L. | N/A | Exploring the bounded rationality in human decision anomalies through an assemblable computational framework | |
| 预期性平滑眼动与视觉运动概率成比例：目标速度和加速度的作用 | Carneiro Morita, V. | N/A | Anticipatory smooth eye movements scale with the probability of visual motion: role of target speed and acceleration | |
| RNPS1 在 PSAP 复合物中控制细胞周期内的周期性前体 mRNA 剪接 | Fukumura, K. | N/A | RNPS1 in PSAP complex controls periodic pre-mRNA splicing over the cell cycle | |
| 甲虫幼虫释放的化学信号能够触发植物病原体的增殖，并可能诱导其毒力基因的表达。 | Cambon, M. C. | N/A | Chemical cues from beetle larvae trigger proliferation and putative virulence gene expression of a plant pathogen | |
| 多尺度研究丘脑状态依赖性反应性 | Overwiening, J. | N/A | A Multi-Scale Study of Thalamic State-Dependent Responsiveness | |
| 纤毛转录程序在精子发生过程中通过拮抗转录因子的调控 | Wang, W. | N/A | Control of ciliary transcriptional programs during spermatogenesis by antagonistic transcription factors | |
| p110α依赖的肝细胞信号传导对肝脏基因表达及其在代谢相关脂肪性肝病（MASLD）中的重塑至关重要。 | Regnier, M. | N/A | p110alpha-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD | |
| 酪胺修饰的透明质酸分子量对THP-1和外周血单核细胞衍生的巨噬细胞极化状态的影响 | Wychowaniec, J. K. | N/A | Effect of molecular weight of tyramine-modified hyaluronan on polarization state of THP-1 and peripheral blood mononuclear cells-derived macrophages | |
| 用微藻替代饮食中的鱼油对金头鲷中肠细菌微生物群的影响 | Katsoulis-Dimitriou, S. | N/A | The effect of dietary fish oil replacement by microalgae on the gilthead sea bream midgut bacterial microbiota | |
| 在观看电影时将思维模式映射到大脑活动上 | Wallace, R. S. | N/A | Mapping patterns of thought onto brain activity during movie-watching | |
| 利用单细胞转录组学识别可重复的转录调控因子共表达模式 | Morin, A. | N/A | Identifying Reproducible Transcription Regulator Coexpression Patterns with Single Cell Transcriptomics | |
| 蜂群衰竭失调对蜜蜂生存产生负面影响：实验与元分析证据 | Ostap-Chec, M. | N/A | Nosemosis negatively affects honeybee survival: experimental and meta-analytic evidence | |
| 根瘤菌效应蛋白NopT靶向豆科植物百脉根中的结瘤因子受体，以调控共生关系 | Bao, H. | N/A | The Rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus | |
| 使用生成模型预测蛋白质折叠的绝对稳定性 | Cagiada, M. | N/A | Predicting absolute protein folding stability using generative models | |
| 单细胞分析揭示了宫颈腺癌的肿瘤内异质性和免疫抑制微环境 | Peng, Y. | N/A | Single-cell profiling reveals the intratumor heterogeneity and immunosuppressive microenvironment in cervical adenocarcinoma | |
| MftG通过将霉菌素氧化与呼吸作用相连接，对分枝杆菌的乙醇代谢至关重要。 | Graca, A. P. | N/A | MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration | |
| 希瓦氏菌可能是堆肥蚯蚓（Eisenia fetida）肠道土壤中多不饱和脂肪酸的生产者。 | Wittlinger, J.-P. | N/A | Shewanella is a putative producer of polyunsaturated fatty acids in the gut soil of the composting earthworm Eisenia fetida | |
| 捕食者-猎物幂律的自上而下起源的一般机制 | Mazzarisi, O. | N/A | General mechanisms for a top-down origin of the predator-prey power law | |
| 共享通路特异性网络机制：多巴胺与深部脑刺激治疗帕金森病的研究 | Binns, T. S. | N/A | Shared pathway-specific network mechanisms of dopamine and deep brain stimulation for the treatment of Parkinson's disease | |
| 诱导乙型肝炎核心蛋白聚集，靶向非常规结合位点 | Khayenko, V. | N/A | Induction of Hepatitis B Core Protein Aggregation Targeting an Unconventional Binding Site | |
| 软骨细胞中的eQTLs（表达数量性状位点）、染色质可及性及三维染色质结构为骨关节炎风险提供了机制性见解。 | Kramer, N. E. | N/A | Response eQTLs, chromatin accessibility, and 3D chromatin structure in chondrocytes provide mechanistic insight into osteoarthritis risk | |
| 产乙酸菌对H2的消耗遵循一级动力学。 | Munoz, L. | N/A | H2 consumption by acetogenic bacteria follows first-order kinetics | |
| 胸主动脉三维几何结构 | Beeche, C. | N/A | Thoracic Aortic Three-Dimensional Geometry | |
| 对超过30,000种化合物进行高通量筛选，以寻找对抗胃肠道线虫寄生虫的抗蠕虫药物 | Elfawal, M. A. | N/A | High-throughput screening of more than 30,000 compounds for anthelmintics against gastrointestinal nematode parasites | |
| 对视觉特征的敏感性在无意视盲中 | Nartker, M. | N/A | Sensitivity to visual features in inattentional blindness | |
| 单细胞转录组学揭示了21三体和GATA1s对造血的个体及协同效应 | Takasaki, K. | N/A | Single-cell transcriptomics reveal individual and synergistic effects of Trisomy 21 and GATA1s on hematopoiesis | |
| Kermut: 蛋白质变体效应的复合核回归 | Groth, P. M. | N/A | Kermut: Composite kernel regression for protein variant effects | |
| 不太格子化：内部表征的循环神经网络路径整合了不止一个代理 | Redman, W. | N/A | Not so griddy: Internal representations of RNNs path integrating more than one agent | |
| 在秀丽隐杆线虫中，对铜绿假单胞菌的跨代反应并不显著 | Gainey, D. P. | N/A | Reported transgenerational responses to Pseudomonas aeruginosa in C. elegans are not robust | |
| 解耦个体宿主反应与免疫细胞衔接子细胞毒性效力 | Gonzalez Gutierrez, C. | N/A | Decoupling individual host response and immune cell engager cytotoxic potency | |
| 对巴布亚新几内亚丹皮尔群岛弗格森岛的鸟类学调查揭示了新的岛屿记录和值得注意的自然历史观察结果。 | Boersma, J. | N/A | An ornithological survey of Fergusson Island, D'Entrecasteaux Archipelago, Papua New Guinea, reveals new island records and noteworthy natural history observations | |
| 用于条件脑模板的深度微分同胚网络 | Whitbread, L. | N/A | Deep-diffeomorphic networks for conditional brain templates | |
| 平滑肌细胞中RNA编辑酶ADAR1的表达调控动脉粥样硬化中RNA传感器MDA5的激活 | Weldy, C. S. | N/A | Smooth muscle expression of RNA editing enzyme ADAR1 controls activation of RNA sensor MDA5 in atherosclerosis | |
| 氮化硅通过激活线粒体氧化磷酸化和新生血管化促进骨传导 | Gonzales, W. D. | N/A | Silicon Nitride Induces Osteoconduction Via Activated Mitochondrial Oxidative Phosphorylation and Neovascularization | |
| 嗅觉皮层输出招募并塑造了不同的大脑广泛时空网络 | Ma, T. | N/A | Olfactory cortical outputs recruit and shape distinct brain-wide spatiotemporal networks | |
| 使用松露犬有助于了解美国俄勒冈州西部Genea（Pyronemataceae）的生态及其丰富的发生情况。 | Dawson, H. R. | N/A | Use of a truffle dog provides insight into the ecology and abundant occurrence of Genea (Pyronemataceae) in western Oregon, U.S.A. | |
| 利用扩展拼接光片显微镜对无性扁形虫的神经元异速生长和神经肌肉投射进行三维重建 | Lu, J. | N/A | 3D Reconstruction of Neuronal Allometry and Neuromuscular Projections in Asexual Planarians Using Expansion Tiling Light Sheet Microscopy | |
| 尾状核的集成单细胞多组学分析揭示了酒精使用障碍的关键机制 | Green, N. | N/A | Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder | |
| 从混乱的化学到生态学：前生物学上合理的化学系统中的自催化与遗传性 | Sokolskyi, T. | N/A | From messy chemistry to ecology: autocatalysis and heritability in prebiotically plausible chemical systems | |
| BCL2L13 影响自噬和鞘脂代谢，但不影响胶质母细胞瘤中的替莫唑胺耐药性 | Clark, C. | N/A | BCL2L13 Influences Autophagy and Ceramide Metabolism without Affecting Temozolomide Resistance in Glioblastoma | |
| 铁状态和乙烯信号在应对大豆同时遭受铁缺乏和干旱胁迫的抗逆性中的作用 | Hasan, M. R. | N/A | Role of iron status and ethylene signaling in stress resilience of soybean exposed to combined iron deficiency and drought | |
| 慢性弓形虫感染过程中淀粉样颗粒积累的动力学与囊内缓殖子复制相关。 | Tripathi, A. | N/A | Dynamics of amylopectin granule accumulation during the course of the chronic Toxoplasma infection is linked to intra-cyst bradyzoite replication. | |
| Kontextual：重新构建空间组学数据分析揭示了图像间一致的细胞关系 | Ameen, F. | N/A | Kontextual: Reframing analysis of spatial omics data reveals consistent cell relationships across images | |
| 人类小脑中浦肯野细胞树突的非等比扩张和增强的区室化 | Busch, S. E. | N/A | Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum | |
| 应激诱导小蛋白的翻译组学分析揭示了不同信号系统之间出乎意料的联系 | Vellappan, S. | N/A | Translational profiling of stress-induced small proteins uncovers an unexpected connection among distinct signaling systems | |
| 番茄半胱氨酸蛋白酶抑制剂SlCYS8作为马铃薯抗旱性和块茎产量的触发因子 | Dorval, M. | N/A | Tomato cystatin SlCYS8 as a trigger of drought tolerance and tuber yield in potato | |
| 少样本一致性神经解码（FALCON）基准算法 | Karpowicz, B. M. | N/A | Few-shot Algorithms for Consistent Neural Decoding (FALCON) Benchmark | |
| 靶向与帕金森病相关的LRRK2的II型激酶抑制剂 | Raig, N. D. | N/A | Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2 | |
| TIRTL-seq：深度、定量且经济实惠的配对TCR受体组测序 | Pogorelyy, M. V. | N/A | TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing | |
| 终身健身益处包括繁殖地点的忠诚度和近亲繁殖成本低，这使得近亲繁殖容忍度在一种鸟类合作繁殖者中得以实现。 | Shah, S. | N/A | Lifetime fitness benefits of breeding site fidelity and low costs of inbreeding permit inbreeding tolerance in an avian cooperative breeder | |
| 寄生传播时间的选择塑造了宿主冈比亚按蚊的转录反应，并提示了免疫逃避机制 | Silva, L. M. | N/A | Selection on time to parasite transmission shapes the host Anopheles gambiae transcriptional response and suggests immune evasion | |
| Tau P301S转基因小鼠表现出类似于进行性核上性麻痹的步态和眼球运动障碍。 | Creed, R. B. | N/A | Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy | |
| 巨核细胞组装了一个三维的细胞外基质笼，这个笼子控制着它们的成熟和锚定到血管壁的微环境。 | Masson, C. | N/A | Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche | |
| 便携式现场DNA测序用于快速检测病原体及抗菌药物耐药性：概念验证研究 | Pillay, S. | N/A | Portable In-Field DNA Sequencing for Rapid Detection of Pathogens and Antimicrobial Resistance: A Proof-of-Concept Study | |
| Danicamtiv通过减少肌球蛋白的工作冲程，但通过激活细肌丝来增强收缩。 | Scott, B. | N/A | Danicamtiv reduces myosin's working stroke but enhances contraction by activating the thin filament | |
| 在来自狗衰老项目的多样化犬类群体中，转座子的DNA甲基化模式揭示了衰老差异 | Mariner, B. L. | N/A | DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project | |
| 活性氧解毒作用有助于脓肿分枝杆菌对抗生素的存活 | Bates, N. A. | N/A | Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival | |
| 在癌症的网络基础分层分析中整合遗传和基因表达数据 | Liou, K. | N/A | Integrating genetic and gene expression data in network-based stratification analysis of cancers | |
| 涉及lncRNA MB3及驱动基因MYC和OTX2的电路通过HMGN5调控TGF-β通路，抑制了3型髓母细胞瘤中的细胞凋亡。 | Grandioso, A. | N/A | A circuit involving the lncRNA MB3 and the driver genes MYC and OTX2 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5 | |
| 象牙喙啄木鸟与蓝松鸦在频谱图层面的比较显示出差异 | Williams, J. D. | N/A | Ivory-billed Woodpecker and Blue Jay kent comparisons at spectrogram level reveal differences | |
| 邻近标记揭示了人类线粒体导入受体蛋白TOMM20和TOMM70的不同相互作用伙伴 | Akram, S. | N/A | Proximity labeling reveals differential interaction partners of the human mitochondrial import receptor proteins TOMM20 and TOMM70 | |
| 表达人α1,4-半乳糖基转移酶的B4GALT5缺陷CHO-Lec2细胞：用于研究志贺毒素受体的糖工程细胞模型 | Mikolajczyk, K. | N/A | B4GALT5-deficient CHO-Lec2 cells expressing human alpha1,4-galactosyltransferase: a glycoengineered cell model for studying Shiga toxin receptors | |
| 解开应力纤维和未成束肌动蛋白网络对细胞形状响应的皮质张力各向异性贡献的纠缠 | Fage, F. | N/A | Disentangling the contributions of stress fibres and the unbundled actin meshwork to the anisotropy of cortical tension in response to cell shape | |
| 缓症链球菌群糖脂的生物合成及其在生理和抗生素敏感性中的作用 | Wei, Y. | N/A | Biosynthesis of mitis group streptococcal glycolipids and their roles in physiology and antibiotic susceptibility | |
| 使用Opal-TSA放大技术进行三维多重免疫组织化学，以增强肺结核病变成像 | Lata, S. | N/A | 3D Multiplexed Immunohistochemistry Using Opal-TSA Amplification for Enhanced Imaging of Pulmonary TB Lesions | |
| 对古代信号通路中的自然变异进行大规模并行实验分析，揭示了净化选择和局部适应的存在。 | Aguilar-Rodriguez, J. | N/A | Massively parallel experimental interrogation of natural variants in ancient signaling pathways reveals both purifying selection and local adaptation | |
| CFC-seq：全长加帽RNA的鉴定揭示增强子来源的转录 | Yip, C. W. | N/A | CFC-seq: identification of full-length capped RNAs unveil enhancer-derived transcription | |
| 一个大型复杂系统会形成图灵图案吗？ | Piskovsky, V. | N/A | Will a large complex system form Turing patterns? | |
| 1.6埃分辨率下的光系统II相关锰结合TPM结构域蛋白的晶体结构 | Vidal-Meireles, A. | N/A | Crystal structure of a Photosystem II-related, Manganese-binding, TPM-domain protein at a 1.6 A resolution | |
| 工作记忆连接认知、情感与大脑结构：基于人类连接组计划-青年成人数据的多层网络分析 | Firman-Sadler, L. | N/A | Working Memory Bridges Cognition, Emotion, and Brain Structure: A Multilayer Network Analysis of the Human Connectome Project-Young Adult | |
| 人脑内嗅皮层中用于序列记忆的分层坐标系统。 | Shpektor, A. | N/A | A hierarchical coordinate system for sequence memory in human entorhinal cortex. | |
| 癌细胞衍生的cGAMP限制了肿瘤相关CD8+ T细胞的活性 | Herbst, M. | N/A | Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells | |
| 一种VersaTile方法用于重新编程R2型tailocin对不同血清型的埃希氏大肠杆菌和肺炎克雷伯菌的特异性 | Dams, D. | N/A | A VersaTile approach to reprogram the specificity of the R2-type tailocin towards different serotypes of Escherichia coli and Klebsiella pneumoniae | |
| 利用改良的群体分离分析法鉴定出酿酒酵母对铜抗性的上位性和隐性数量性状位点 | Buzby, C. | N/A | Epistasis and cryptic QTL identified using modified bulk segregant analysis of copper resistance in budding yeast | |
| 通过改良的批量分离分析法鉴定出酿酒酵母铜抗性的上位性和隐秘数量性状位点 | Buzby, C. | N/A | Epistasis and cryptic QTL identified using modified bulk segregant analysis of copper resistance in budding yeast | |
| Bax抑制肽的计算设计 | Vlaar, T. | N/A | Computational design of Bax-inhibiting peptides | |
| 机械拉伸诱导细胞集体排列 | Shi, X. | N/A | Mechanical stretch induced collective cell alignment | |
| GESIAP3.0：基于传感器的图像分析程序，用于体内传输可视化 | Zhu, R. E. | N/A | GESIAP3.0: Sensor-based Image Analysis Program for Transmission Visualization In Vivo | |
| 神经TD：一种基于时频的多模态学习方法，用于分析神经活动中的时间延迟 | Huang, X. | N/A | NeuroTD: A Time-Frequency Based Multimodal Learning Approach to Analyze Time Delays in Neural Activities | |
| 飞翔还是不飞翔，这是个问题：一种用于质谱中肽段可检测性预测的深度学习模型 | Abdul-Khalek, N. | N/A | To fly, or not to fly, that is the question: A deep learning model for peptide detectability prediction in mass spectrometry | |
| 基于强化学习的基因组数据共享信标动态隐私保护方法 | Poorghaffar Aghdam, M. | N/A | A Reinforcement Learning-based Approach for Dynamic Privacy Protection in Genomic Data Sharing Beacons | |
| TIPP3 和 TIPP3-fast：改进的宏基因组丰度分析 | Shen, C. | N/A | TIPP3 and TIPP3-fast: Improved Abundance Profiling in Metagenomics | |
| 脂筏稳定性和蛋白质-筏分区的小分子调节剂 | Stefanski, K. M. | N/A | Small-molecule modulators of lipid raft stability and protein-raft partitioning | |
| GPCRVS - 基于人工智能的GPCR虚拟筛选决策支持系统 | Latek, D. | N/A | GPCRVS - AI-driven decision support system for GPCR virtual screening | |
| 应用2H2O量化年轻训练有素和未经训练的男性和女性的红细胞蛋白合成率 | Kontro, H. | N/A | Application of 2H2O to quantify red blood cell protein synthesis rates in young trained and untrained males and females | |
| 使用非线性混合效应模型对钙-钙调蛋白动力学方案进行拟合和比较，以共同数据集为依据 | Linkevicius, D. | N/A | Fitting and comparison of calcium-calmodulin kinetic schemes to a common data set using non-linear mixed effects modelling | |
| 空间转录组学揭示了生精上皮周期的时间结构及精确的Sertoli-生殖细胞同步化 | Chakravorty, A. | N/A | Spatial Transcriptomics Reveals the Temporal Architecture of the Seminiferous Epithelial Cycle and Precise Sertoli-Germ Synchronization | |
| 在单细胞分辨率下绘制肿瘤内髓系细胞与T细胞的相互作用图谱，揭示了克服检查点抑制剂耐药性的靶点 | Bridges, K. | N/A | Mapping intratumoral myeloid-T cell interactomes at single-cell resolution reveals targets for overcoming checkpoint inhibitor resistance | |
| 在发育过程中，突触基因表达通过保守的染色质调控因子进行协调。 | Kentro, J. A. | N/A | Synaptic gene expression is coordinated across development by conserved chromatin regulators | |
| 一项关于社区为基础的狂犬病疫苗接种策略有效性的随机对照试验 | Lankester, F. | N/A | A randomized controlled trial of the effectiveness of a community-based rabies vaccination strategy | |
| perR对艰难梭菌630Δerm中氧气敏感性、基因表达及小鼠感染的影响 | Gregory, A. L. | N/A | Impacts of perR on oxygen sensitivity, gene expression, and murine infection in Clostridioides difficile 630Δerm | |
| 局部异质性土壤病毒和原核生物对规定的烧除的响应与混合针叶林中斑块状的烧除严重程度相对应 | Geonczy, S. | N/A | Locally heterogeneous soil viral and prokaryotic responses to prescribed burn correspond with patchy burn severity in a mixed conifer forest | |
| 人类N-糖基化途径中的宏观进化模式对比 | Kifer, D. | N/A | Contrasting macroevolutionary patterns in the human N-glycosylation pathway | |
| 宿主扩散与寄生物毒力在复杂景观中的协同进化。 | Deshpande, J. N. | N/A | Co-evolution of host dispersal and parasite virulence in complex landscapes. | |
| Ana1的N端和C端部分的相互作用允许中心粒复制但不允许延长 | Nagy, A. | N/A | Interactions of N- and C-terminal parts of Ana1 permitting centriole duplication but not elongation | |
| 亚洲黄蜂（Vespa velutina nigrithorax，du Buysson 1905）在斯洛伐克的最东部分布：迫切需要加强检测和跨区域监测 | Balazs, K. | N/A | Easternmost distribution of Asian hornet (Vespa velutina nigrithorax, du Buysson 1905) in Slovakia: Urgent need for advanced detection and interregional monitoring | |
| CDC45突变对DNA复制和基因组稳定性的影响 | Denkiewicz-Kruk, M. | N/A | The effects of CDC45 mutations on DNA replication and genome stability | |
| GBRAP：一个全面的数据库和工具，用于探索所有生命领域的基因组多样性 | Yaddehige, S. K. | N/A | GBRAP: A Comprehensive Database and Tool for Exploring Genomic Diversity Across All Domains of Life | |
| 威瑟姆森林中欧洲栎（Quercus robur）的遗传多样性和群体结构 | Hung, T. H. | N/A | Genetic diversity and population structure of pedunculate oaks (Quercus robur) in Wytham Woods | |
| 为雄性山地大猩猩提供了一个接近端粒到端粒的相位参考组装 | Nelson, D. R. | N/A | A near telomere-to-telomere phased reference assembly for the male mountain gorilla | |
| 提高大型流行病学研究中体细胞突变分析的准确性：解决无匹配正常样本病例的问题 | Arora, A. | N/A | Improving Accuracy of Somatic Mutation Profiling in Large Epidemiologic Studies: Addressing Cases without Matched Normal Samples | |
| 利用蛋白质大型语言模型设计新型脱卤酶 | Garcia, L. N. | N/A | Design of Novel Dehalogenases using Protein Large Language Models | |
| UnCOT-AD：无配对跨组学翻译实现阿尔茨海默病预测的多组学整合 | Abir, A. R. | N/A | UnCOT-AD: Unpaired Cross-Omics Translation Enables Multi-Omics Integration for Alzheimer's Disease Prediction | |
| 基于扩散的人工基因组及其在本地血统推断中的实用性 | Szatkownik, A. | N/A | Diffusion-based artificial genomes and their usefulness for local ancestry inference | |
| 使用分子荧光寿命传感器监测单个DNA折纸纳米结构的涂层 | Scheckenbach, M. | N/A | Monitoring the Coating of Single DNA Origami Nanostructures with a Molecular Fluorescence Lifetime Sensor | |
| 2013-2016年疫情期间埃博拉病毒糖蛋白A82V变异体膜融合活性增强的分子基础：来自模拟与实验的见解 | Durham, N. D. | N/A | Molecular basis for the increased membrane fusion activity of the Ebola virus glycoprotein A82V variant from the 2013-2016 epidemic: insights from simulations and experiments | |
| 有机和无机污染物及其混合物对发育暴露的斑马鱼代谢健康和基因表达的影响 | Berube, R. | N/A | Effects of organic and inorganic contaminants and their mixtures on metabolic health and gene expression in developmentally exposed zebrafish | |
| 基于片段的小分子抑制剂开发，靶向结核分枝杆菌胆固醇代谢 | Kavanagh, M. E. | N/A | Fragment-based development of small molecule inhibitors targeting Mycobacterium tuberculosis cholesterol metabolism | |
| 机器学习模型揭示了与植物生物钟相关的环境和遗传因素 | Reynolds, C. | N/A | Machine learning models reveal environmental and genetic factors associated with the plant circadian clock | |
| 机器学习方法在干燥综合征单细胞转录组分析中的应用揭示了B细胞和T淋巴细胞激活状态的改变 | McDermott, M. | N/A | Machine Learning Approach to Single Cell Transcriptomic Analysis of Sjogren's Disease Reveals Altered Activation States of B and T Lymphocytes | |
| 领土行为作为非社会性哺乳动物中社会微生物传播的途径 | Petrullo, L. | N/A | Territorial behavior as a route of social microbial transmission in an asocial mammal | |
| LCL：用于谱系条形码单细胞RNA测序数据的对比学习 | Yang, S. J. | N/A | LCL: Contrastive Learning for Lineage Barcoded scRNA-seq Data | |
| 通过本地祖先推断在gnomAD中改进的等位基因频率 | Atkinson, E. G. | N/A | Improved Allele Frequencies in gnomAD through Local Ancestry Inference | |
| 高孔隙率颗粒状水凝胶，通过静电纺丝水凝胶纤维增强，实现长期稳定性 | Whitewolf, J. | N/A | Highly porous granular hydrogels reinforced by electrospun hydrogel fibers for long-term stability | |
| 运输相关因素对人脑皮质神经元内在及突触特性的影响：一项比较研究 | Qi, G. | N/A | Transport-Related Effects on Intrinsic and Synaptic Properties of Human Cortical Neurons: A Comparative Study | |
| 视网膜小胶质细胞来源的S100A9在西方饮食喂养的Ossabaw猪视网膜中激发NLRP3炎症小体 | Lim, R. R. | N/A | Retinal microglia-derived S100A9 incite NLRP3 inflammasome in a Western diet fed Ossabaw pig retina | |
| 结节性硬化症皮质结节的单细胞分析显示分子结构保存及代谢的大规模重构 | Sorensen, F. N. F. | N/A | Single-cell profiling of cortical tubers in tuberous sclerosis complex shows molecular structure preservation and massive reorganization of metabolism | |
| RATS：使用低失真对齐切线空间的无监督流形学习 | Kohli, D. | N/A | RATS: Unsupervised manifold learning using low-distortion alignment of tangent spaces | |
| 瞳孔扩张提供了一个预测误差的时间窗口 | Colizoli, O. | N/A | Pupil dilation offers a time-window on prediction error | |
| 在向内凹陷的杆状突触中，几何扭曲减缓了谷氨酸的扩散并塑造了突触反应：来自解剖学上真实的蒙特卡罗模拟的见解 | Thoreson, W. B. | N/A | Geometric tortuosity at invaginating rod synapses slows glutamate diffusion and shapes synaptic responses: insights from anatomically realistic Monte Carlo simulations | |
| 缺乏赖氨酸和磨损的果蝇Act与dSarm并行作用，在dNmnat耗尽后驱动神经退行性变 | Avetisyan, A. | N/A | Drosophila with-no-lysine and frayed Act in Parallel to dSarm to Drive Neurodegeneration Following dNmnat Depletion | |
| 次级运动皮层追踪决策价值，并在非指令性选择过程中支持行为灵活性 | Augusto, E. | N/A | Secondary motor cortex tracks decision value and supports behavioral flexibility during non-instructed choice | |
| 上丘眼跳前场电位主要受视觉感官对上视野的偏好影响。 | Hafed, Z. M. | N/A | Superior colliculus peri-saccadic field potentials are dominated by a visual sensory preference for the upper visual field | |
| 星形胶质细胞转录组分析发现，糖基化蛋白5下调是阿尔茨海默病模型中突触功能障碍的一个因素。 | Salas, I. H. | N/A | Astrocyte transcriptomic analysis identifies glypican 5 downregulation as a contributor to synaptic dysfunction in Alzheimer disease models | |
| 在老鼠视网膜中，杆状细胞的输入信号仅通过杆-锥耦合方式到达水平细胞的细胞体。 | Thoreson, W. | N/A | Rod inputs arrive at horizontal cell somas in mouse retina solely via rod-cone coupling | |
| 单个神经元EI平衡的短期可塑性可以检测模式转换 | Asopa, A. | N/A | Short-term plasticity of EI balance at single neurons can detect pattern transitions | |
| WTools：一个基于MATLAB的时间-频率分析工具箱 | Ferrari, A. | N/A | WTools: a MATLAB-based toolbox for time-frequency analysis | |
| 抽象规则泛化以构成新意义时，会招募前顶叶控制网络 | Zheng, X. Y. | N/A | Abstract rule generalization for composing novel meaning recruits the frontoparietal control network | |
| 用于声源分离的基于双耳时间差的哺乳动物下丘模型 | Leibold, C. | N/A | A mammalian inferior colliculus model for sound source separation using interaural time differences | |
| 任务执行期间结构-功能脑网络耦合揭示与智力相关的沟通策略 | Popp, J. L. | N/A | Structural-Functional Brain Network Coupling During Task Performance Reveals Intelligence-Relevant Communication Strategies | |
| 不同地区经济变量的独特表征及前额叶皮层的预测 | Majumdar, A. | N/A | Distinct representations of economic variables across regions and projections of the frontal cortex | |
| 多尺度激发-抑制平衡动力学：整合代谢物动力学与时变执行网络 | Saviola, F. | N/A | Multiscale excitation-inhibition balance dynamics: integrating metabolite kinetics with time-varying executive networks | |
| 观察几何学驱动着对物体运动和深度的灵活感知。 | Xu, Z.-X. | N/A | Viewing geometry drives flexible perception of object motion and depth | |
| IL-17A改变人类皮质发育在母体免疫激活的三维体外模型中 | Assir, M. Z. K. | N/A | IL-17A Alters Human Cortical Development in a 3D Ex Vivo Model of Maternal Immune Activation | |
| 顺序转录程序支撑静息海马干细胞的激活。 | Rigo, P. | N/A | Sequential transcriptional programs underpin activation of quiescent hippocampal stem cells. | |
| 细菌对氧化应激因子的改变影响流感病毒A型的环境稳定性 | Williams, M. R. | N/A | Bacterial alteration of redox stressors impact environmental stability of Influenza A virus | |
| 时空转录组分析揭示了发育过程中分子梯度模式以及沿耳蜗轴的音调组织。 | Yan, M. | N/A | Spatiotemporal transcriptomic analyses reveal molecular gradient patterning during development and the tonotopic organization along cochlear axis | |
| 非甾体抗炎药（NSAID）介导的环氧合酶抑制作用破坏了蝾螈胚胎中外胚层衍生物的形成。 | Marshall, E. J. | N/A | NSAID-mediated cyclooxygenase inhibition disrupts ectodermal derivative formation in axolotl embryos | |
| 发育中的人类生殖道在单细胞分辨率下的时空图谱 | Lorenzi, V. | N/A | Spatiotemporal map of the developing human reproductive tract at single-cell resolution | |
| Tit wit：城市化梯度上认知变异的环境和遗传驱动因素 | Thompson, M. J. | N/A | Tit wit: environmental and genetic drivers of cognitive variation along an urbanization gradient | |
| 一种新型人类TBCK-神经元细胞模型导致严重的神经退行性变，并通过抑制线粒体分裂得到部分挽救 | Angireddy, R. | N/A | A Novel Human TBCK- Neuronal Cell Model Results in Severe Neurodegeneration and Partial Rescue with Mitochondrial Fission Inhibition | |
| β频带去同步化的因果作用：个性化高清晰度经颅交流电刺激改善双手运动控制 | Van Hoornweder, S. | N/A | The Causal Role Of Beta Band Desynchronization: Individualized High-Definition Transcranial Alternating Current Stimulation Improves Bimanual Motor Control | |
| 语言和情感韵律：一个统一视角。皮质韵律组织的系统综述与ALE元分析 | Themistocleous, C. | N/A | Linguistic and Affective Prosody. A Unifying Perspective:A Systematic Review and ALE Meta-Analysis of the Cortical Organization of Prosody | |
| 眼动系统微刺激下稳健目标选择背后的神经机制 | Rakhshan, M. | N/A | Neural mechanisms underlying robust target selection in response to microstimulation of the oculomotor system | |
| BrainACTIV：利用基于扩散的图像操作识别驱动皮层选择性的视觉语义属性 | Garcia Cerdas, D. | N/A | BrainACTIV: Identifying visuo-semantic properties driving cortical selectivity using diffusion-based image manipulation | |
| 使用两步非局部主成分分析方法去噪复数扩散磁共振图像 | Ye, X. | N/A | Denoising complex-valued diffusion MR images using a two-step non-local principal component analysis approach | |
| 心理旋转是对视觉化倾向的一种较弱的衡量方式。 | Arnold, D. H. | N/A | Mental Rotation is a weak measure of the propensity to visualise. | |
| 骨桥蛋白在M2和M4型内在光敏视网膜神经节细胞中的表达 | Lindner, M. | N/A | Expression of Osteopontin in M2 and M4 intrinsically photosensitive retinal ganglion cells | |
| 神经化小鼠嗅觉类器官的协议 | Ozgun, A. | N/A | A Protocol for Neuralized Murine Olfactory Organoids | |
| 使用智能手机对手部和脚部运动技能进行15秒评估 | Takagi, A. | N/A | 15 second assessment of hand and foot motor skill using a smartphone | |
| 向无名质投射的食欲素能神经元介导觉醒和镇痛。 | Xiang, X. | N/A | Orexinergic projections to substantia innominata mediate arousal and analgesia | |
| 野生型超氧化物歧化酶1的成熟受损与帕金森病脑部神经退行性变及一种新型小鼠模型相关 | Abdeen, A. H. | N/A | Impaired maturation of wild-type superoxide dismutase 1 associated with neurodegeneration in Parkinson disease brain and a novel murine model | |
| 使用深度学习方法进行基于模型的深脑刺激控制 | Saradhi, S. | N/A | Using a Deep Learning Approach for Model-based Control of Deep Brain Stimulation | |
| 小鼠睡眠剥夺：超越慢波反弹的观察 | Magyar, T. Z. | N/A | Sleep Deprivation in Mice: Looking Beyond the Slow Wave Rebound | |
| 持续的捕食者气味应激源通过前边缘皮层中的GABA-A受体适应增强了雄性大鼠对酒精的内感受敏感性，但在雌性大鼠中未观察到此效应。 | Tyler, R. E. | N/A | The persistent effects of predator odor stressor enhance interoceptive sensitivity to alcohol through GABA-A receptor adaptations in the prelimbic cortex in male, but not female rats | |
| PFOS对甲状腺激素驱动的神经发育和非洲爪蟾蝌蚪类似变态变化的剂量依赖性影响 | Zirkle, K. | N/A | Dose-Dependent Effects of PFOS on Thyroid Hormone-Driven Neurodevelopment and Metamorphic-like change in Xenopus laevis larvae | |
| 内侧隔区表达小清蛋白的抑制性神经元在Dravet综合征小鼠模型中受损 | Zhu, L. | N/A | Medial septum parvalbumin-expressing inhibitory neurons are impaired in a mouse model of Dravet Syndrome | |
| 不同的血清素能神经元调节对蔗糖的食欲和对蛋白质的饥饿感。 | Dorn, K. | N/A | Different serotonergic neurons regulate appetite for sucrose and hunger for proteins | |
| 阿尔茨海默病中性与区域特异性的自噬与线粒体自噬紊乱：将细胞功能障碍与认知衰退相联系 | Adlimoghaddam, A. | N/A | Sex and Region-Specific Disruption of Autophagy and Mitophagy in Alzheimer's Disease: Linking Cellular Dysfunction to Cognitive Decline | |
| 基于细胞类型特异性微电路的猕猴与小鼠皮质层次比较 | Glatigny, M. | N/A | Comparison of the cortical hierarchy between macaque monkeys and mice based on cell-type specific microcircuits | |
| 使用几何特征模态对大脑皮层图谱的半球不对称性进行多尺度定量分析 | Milloz, A. | N/A | Multiscale Quantification of Hemispheric Asymmetry in Cortical Maps Using Geometric Eigenmodes | |
| 脂质失衡影响神经元树突生长和维持在人神经酰胺合酶疾病模型中 | Ziegler, A. B. | N/A | Lipid Disbalance Affects Neuronal Dendrite Growth and Maintenance in a Human Ceramide Synthase Disease Model | |
| 公共物品游戏中合作行为中对共同玩家身份和声誉处理的神经关联 | Sampaio, W. M. | N/A | Neural correlates of co-players' identity and reputation processing on cooperation in the public goods game | |
| STRIPAK复合体在施万细胞的径向排序和层粘连蛋白受体表达中是必需的。 | Weaver, M. R. | N/A | The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells | |
| 通过源分离实现宽带脑网络估计（BROAD-NESS） | Bonetti, L. | N/A | BROADband brain Network Estimation via Source Separation (BROAD-NESS) | |
| 饲养期间的高温会降低黄鳍鲈幼体的游泳能力，并扰乱其新陈代谢。 | Easwaramoorthy, M. | N/A | Elevated temperature during rearing diminishes swimming and disturbs the metabolism of yellow perch larvae | |
| 一种用于全基因组昼夜节律生物标志物检测的贝叶斯框架 | Ding, H. | N/A | A Bayesian Framework for Genome-wide Circadian Rhythmicity Biomarker Detection | |
| 氧化应激对腺苷A2a受体结构、活性和信号传导的影响 | Company, I. | N/A | The effect of oxidative stress on the Adenosine A2a Receptor structure, activity and signalling | |
| 一种全面且稳健的多重DIA工作流程揭示了与顺铂耐药相关的蛋白质周转调控 | Salovska, B. | N/A | A Comprehensive and Robust Multiplex-DIA Workflow Profiles Protein Turnover Regulations Associated with Cisplatin Resistance | |
| 抗原印迹在仓鼠COVID-19模型中对SARS-CoV-2新变种的体液反应中占主导地位 | Degryse, J. | N/A | Antigenic imprinting dominates humoral responses to new variants of SARS-CoV-2 in a hamster model of COVID-19 | |
| 疫苗诱导的T细胞反应的质量通过多克隆性和高（而非最高）抗原受体亲和力来体现。 | Kocher, K. | N/A | Quality of vaccination-induced T cell responses is conveyed by polyclonality and high, but not maximum, antigen receptor avidity | |
| 噬菌体编码的小RNA劫持宿主的复制机制，以支持噬菌体的裂解周期。 | Silverman, A. | N/A | Phage-encoded small RNA hijacks host replication machinery to support the phage lytic cycle | |
| 微生物对宿主饮食的转录反应维持了美洲大蠊肠道微生物群的稳态 | DePoy, A. N. | N/A | Microbial transcriptional responses to host diet maintain gut microbiome homeostasis in the American cockroach | |
| 在Oz病毒（Thogotovirus属）的基因组中，RNA合成的片段特异性启动子活性 | Akter, L. | N/A | Segment-specific promoter activity for RNA synthesis in the genome of Oz virus, genus Thogotovirus | |
| 非志贺毒素性聚集性肠致病性大肠杆菌O104:H4暴发菌株毒力质粒的遗传和表型分析 | Whelan, R. | N/A | Genetic and phenotypic analysis of the virulence plasmid of a non-Shigatoxigenic enteroaggregative Escherichia coli O104:H4 outbreak strain | |
| 全基因组分析金黄色葡萄球菌在牛奶中生长时的适应性决定因素 | Marli, M. T. | N/A | Genome-wide analysis of fitness determinants of Staphylococcus aureus during growth in milk | |
| 在新发现的深海冷泉中，五年的微生物演替、群落构建与适应 | Liang, Q. | N/A | Microbial succession, community assembly and adaptation over five years in a newly discovered deep-sea cold seep | |
| 细菌核糖体中药物结合位点的进化分歧 | Ekemezie, C. L. | N/A | Evolutionary divergence of drug-binding sites in bacterial ribosomes | |
| 流感A病毒H7纳米抗体识别血凝素头部的保守免疫优势表位，并赋予异源亚型保护作用 | Chen, Z.-S. | N/A | Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection | |
| 疏水性尾部使胞外伴侣蛋白集群蛋白具有多种功能 | Yuste-Checa, P. | N/A | Hydrophobic tails enable diverse functions of the extracellular chaperone clusterin | |
| 线粒体靶向肽治疗药物elamipretide在衰老过程中改善心脏和骨骼肌功能，同时未检测到组织表观遗传或转录组年龄的变化。 | Mitchell, W. | N/A | The mitochondrial-targeted peptide therapeutic elamipretide improves cardiac and skeletal muscle function during aging without detectable changes in tissue epigenetic or transcriptomic age | |
| 棘阿米巴卡氏虫中人工转基因的命运 | Colp, M. J. | N/A | The fate of artificial transgenes in Acanthamoeba castellanii | |
| 对莱茵衣藻（Chlamydomonas reinhardtii）叶绿体横穿类囊体的蛋白质组学分析揭示了新的组分 | Franklin, E. | N/A | Proteomic analysis of the pyrenoid-traversing membranes of Chlamydomonas reinhardtii reveals novel components | |
| PAM-flexible腺嘌呤碱基编辑在携带东亚创始人突变的人源化MPZL2小鼠模型中拯救了听力损失 | Shu, Y. | N/A | PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation | |
| APOBEC3A而非APOBEC3B驱动了人类胃上皮细胞中的脱氨酶突变。 | An, Y. | N/A | APOBEC3A, not APOBEC3B, drives deaminase mutagenesis in human gastric epithelium | |
| 基于地标的基因组差异估计 | Mohan, A. V. | N/A | Landmark-based estimates of genomic disparity | |
| 一个设计的Zn2+传感器结构域将结合信息传递给跨膜组氨酸激酶。 | Hatstat, A. K. | N/A | A designed Zn2+ sensor domain transmits binding information to transmembrane histidine kinases | |
| 开发一种用于在聚球藻PCC 6803中靶向基因上调的CRISPR激活系统 | Bourgade, B. | N/A | Development of a CRISPR activation system for targeted gene upregulation in Synechocystis sp. PCC 6803 | |
| 在嗜热菌Parageobacillus thermoglucosidasius中合成甲基营养的RuMP循环的觉醒。 | Paredes-Barrada, M. | N/A | Awakening of the RuMP cycle for synthetic methylotrophy in the thermophile Parageobacillus thermoglucosidasius. | |
| 糖蛋白K8.1对卡波西肉瘤相关疱疹病毒（KSHV）在狨猴感染模型中的肝脏和骨髓趋向性至关重要 | Hennig, C. S. | N/A | Glycoprotein K8.1 is Critical for Liver and Bone Marrow Tropism of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) in the Marmoset Infection Model | |
| 沙眼衣原体TmeA通过N-WASP与TOCA-1的相互作用促进基座形成 | McCullough, A. | N/A | Chlamydia trachomatis TmeA promotes pedestal formation through N-WASP and TOCA-1 interactions | |
| 宿主PIK3C3通过空泡形成促进福氏志贺氏菌从细胞到细胞的传播 | Rolland, S. J. | N/A | Host PIK3C3 promotes Shigella flexneri spread from cell to cell through vacuole formation | |
| 染色质相关长链非编码RNA-剪接因子凝聚物调控预定位在核斑点附近的基因在低氧应答中的RNA加工过程 | Song, Y. J. | N/A | Chromatin-associated lncRNA-splicing factor condensates regulate hypoxia responsive RNA processing of genes pre-positioned near nuclear speckles | |
| 赖氨酸乙酰乙酰化的调控元件和蛋白质底物的鉴定 | Fu, Q. | N/A | Identification of the Regulatory Elements and Protein Substrates of Lysine Acetoacetylation | |
| 通过基于微芯片的大规模并行合成系统革新大规模DNA合成技术 | Zhang, X. | N/A | Revolutionizing large-scale DNA synthesis with microchip-based massive in parallel synthesis system | |
| 探索短吻鲟（Acipenser brevirostrum）性腺图像的超声分形维度以进行性别鉴定 | Balazadeh, K. | N/A | Exploring fractal dimensions on ultrasound of gonadal images for sex determination in shortnose sturgeon (Acipenser brevirostrum) | |
| 印度黄花木兰花蕾上四种蓟马新记录 | RR, R. | N/A | New Record of Four Thrips Species Infesting Flower Buds of Magnolia champaca in India | |
| 通过三阶段释放技术将昆虫病原线虫整合到可持续有机马铃薯种植中 | Anorbaev, A. R. | N/A | Integrating entomopathogenic nematodes into sustainable organic potato farming through a three-stage release technology | |
| 干旱和与维管植物的共存决定了沿海沙丘藓类群落的动态 | Varela, Z. | N/A | Aridity and coexistence with vascular plants determine the dynamics of coastal dune bryophyte communities | |
| 内脏利什曼病的全球传播发生在人类历史上。 | Reis-Cunha, J. L. | N/A | The global dispersal of visceral leishmaniasis occurred within human history | |
| GENCODE：通过捕获长读长RNA测序大规模扩展长链非编码RNA目录 | Kaur, G. | N/A | GENCODE: massively expanding the lncRNA catalog through capture long-read RNA sequencing | |
| 特质不确定性不容忍对行为灵活性的影响 | Williams, B. | N/A | The influence of trait intolerance of uncertainty on behavioural flexibility | |
| 使用Jalview中的PaSiMap进行序列聚类 | Morell, T. | N/A | Sequence clustering with PaSiMap in Jalview | |
| 5-甲基胞嘧啶和5-羟甲基胞嘧啶是结直肠癌早期检测的协同生物标志物。 | Puddu, F. | N/A | 5-methylcytosine and 5-hydroxymethylcytosine are synergistic biomarkers for early detection of colorectal cancer | |
| 欧洲小麦白粉病菌群体中杀菌剂抗性的基因组监测与分子进化 | Minadakis, N. | N/A | Genomic surveillance and molecular evolution of fungicide resistance in European populations of wheat powderymildew | |
| 老年跑步者中ST段压低与血压反应过度的共存 | Manabe, K. | N/A | Co-existence of ST-Segment Depression and Exaggerated Blood Pressure Response in Older Runners | |
| 作为活体建筑工具的共生：方法与初步成果 | Faucon, P. | N/A | Inosculation As A Tool For Living Architecture: Methods And Early Results | |
| 一种基于轨迹概率分布的布尔网络吸引子景观直观可视化方法 | Chong, K. H. | N/A | An intuitive method to visualize Boolean network attractors landscape based on probability distribution from trajectories | |
| 从单个词语到句子生成：共享的皮层表征，但时间动态不同 | Morgan, A. M. | N/A | From single words to sentence production: Shared cortical representations but distinct temporal dynamics | |
| 触摸文本：盲人读者盲文字母表征的时空演变 | Teng, S. | N/A | Touch to text: Spatiotemporal evolution of braille letter representations in blind readers | |
| 在拦截任务中，超越性能稳定的训练会增加对不可预测扰动的在线调整的使用。 | Couto, C. | N/A | Practice beyond performance stabilization increases the use of online adjustments to unpredictable perturbations in an interceptive task | |
| 小鼠、猕猴和人类中单神经元时间尺度的连续层次结构 | Zeisler, Z. R. | N/A | Consistent hierarchies of single-neuron timescales in mice, macaques and humans | |
| 胎盘因子XIIIA1表达减少与HIV感染孕妇长期抗逆转录病毒治疗及早产相关。 | Ojwach, D. | N/A | Diminished placental Factor XIIIA1 expression associates with long term ART and preterm birth in pregnant people living with HIV. | |
| 生物气溶胶作为云凝结核的能力有限，可能限制了它们在混合相云中引发冰晶形成的潜力。 | Santl-Temkiv, T. | N/A | The limited capacity of bioaerosols to serve as cloud-condensation nuclei may restrict their potential to initiate ice formation in mixed-phase clouds | |
| mcRigor：一种用于增强单细胞数据分析中metacell划分严谨性的统计方法 | Liu, P. | N/A | mcRigor: a statistical method to enhance the rigor of metacell partitioning in single-cell data analysis | |
| # BioRxiv 2024-10-30 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 撤回：呼吸道合胞病毒感染细胞中形成的一种含有病毒RNA和G蛋白的膜性细胞器的超微结构特征 | Vijayakrishnan, S. | N/A | WITHDRAWN: Ultrastructural characterization of a viral RNA and G-protein containing, membranous organelle formed in respiratory syncytial virus infected cells | |
| 黏多糖贮积症III型A、B和C的小鼠模型显示出过度活跃以及少突胶质细胞状态的改变。 | Gerken, E. | N/A | Zebrafish models of Mucopolysaccharidosis types IIIA, B, & C show hyperactivity and changes in oligodendrocyte state | |
| 通过活细胞单分子成像揭示的核受体相互作用网络的惊人特征 | Dahal, L. | N/A | Surprising Features of Nuclear Receptor Interaction Networks Revealed by Live Cell Single Molecule Imaging | |
| 皮层-丘脑通信在熟练运动序列中的动作协调 | Li, Y. | N/A | Cortico-thalamic communication for action coordination in a skilled motor sequence | |
| 从大脑频谱特征预测主体特质：应用于大脑衰老的研究 | Jarne, C. G. | N/A | Predicting subject traits from brain spectral signatures: an application to brain ageing | |
| 从头注释小麦泛基因组揭示了六倍体小麦泛转录组的复杂性和多样性 | White, B. | N/A | De novo annotation of the wheat pangenome reveals complexity and diversity of the hexaploid wheat pan-transcriptome | |
| 数据驱动的AI系统，用于学习如何运行转录组装器 | Shen, Y. | N/A | Data-driven AI system for learning how to run transcript assemblers | |
| 一种通用且有效的去条纹变分方法：应用于光片显微镜、聚焦离子束扫描电镜和遥感图像 | Rottmayer, N. | N/A | A universal and effective variational method for destriping: application to light-sheet microscopy, FIB-SEM and remote sensing images | |
| 腹侧被盖区和黑质致密部神经递质定义的细胞类型的比例和分布 | Conrad, W. S. | N/A | Proportion and distribution of neurotransmitter-defined cell types in the ventral tegmental area and substantia nigra pars compacta | |
| 基于精度的因果推断调节视听时间重校准 | Li, L. | N/A | Precision-based causal inference modulates audiovisual temporal recalibration | |
| 在9.4 T磁场下使用pCASL技术对啮齿动物进行高分辨率灌注成像 | Pires Monteiro, S. | N/A | High-resolution perfusion imaging in rodents using pCASL at 9.4 T | |
| 导航范围扩展促进迁徙性狩猎 | Zhang, Y. | N/A | Navigated range expansion promotes migratory culling | |
| Foldclass 和 Merizo-search：基于嵌入的深度学习工具，用于蛋白质结构域分割、折叠识别和比较 | Kandathil, S. M. | N/A | Foldclass and Merizo-search: embedding-based deep learning tools for protein domain segmentation, fold recognition and comparison | |
| 自上而下起源的捕食者-猎物幂律的一般机制 | Mazzarisi, O. | N/A | General mechanisms for a top-down origin of the predator-prey power law | |
| 马尔可夫场网络整合多模态数据预测免疫系统扰动对猕猴静脉BCG疫苗接种的影响 | Wang, S. | N/A | Markov Field network integration of multi-modal data predicts effects of immune system perturbations on intravenous BCG vaccination in macaques | |
| 疟原虫感染的红细胞的细胞粘附改变了脑内皮细胞中细胞因子、组蛋白和抗病毒蛋白编码基因的表达。 | Allweier, J. | N/A | Cytoadhesion of Plasmodium falciparum-infected red blood cells changes the expression of cytokine-, histone- and antiviral protein-encoding genes in brain endothelial cells | |
| 当常微分方程（ODEs）不可行时，信号传导途径的动态建模 | Rachel, T. J. | N/A | Dynamic modelling of signalling pathways when ODEsare not feasible | |
| 皮质对分层节奏的追踪协调了生物运动的多感官处理 | Shen, L. | N/A | Cortical tracking of hierarchical rhythms orchestrates the multisensory processing of biological motion | |
| 22q11.2缺失突变小鼠海马CA1区的抑制性动力学紊乱 | Herrlinger, S. A. | N/A | Disorganized Inhibitory Dynamics in Hippocampal area CA1 of 22q11.2 Deletion Mutant Mice | |
| 利用转录因子结合和启动子表观基因组模式的可解释模型揭示了在细胞类型背景下与疾病相关的基因及其调控因子。 | Chandra, O. | N/A | Explainable models using transcription factor binding and epigenome patterns at promoters reveal disease-associated genes and their regulators in the context of cell-types | |
| 使用Lamin B受体实现内质网膜接触位点的非破坏性可诱导标记 | Downie, L. | N/A | Non-disruptive inducible labeling of ER-membrane contact sites using the Lamin B Receptor | |
| 埃及伊蚊的VLG-1基因挑战了Vago基因被认为具有抗病毒特性的假设。 | Couderc, E. | N/A | Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes. | |
| 代谢驱动的氧化还原状态对线粒体网络形态的主动调控 | Singh, G. | N/A | Active control of mitochondrial network morphology by metabolism driven redox state | |
| 运输蛋白中最低能量路径的计算。 | Yorke, B. A. | N/A | Calculation of minimum energy pathways in transport proteins. | |
| Cell Ranger版本对Chromium基因表达数据的影响 | Abugessaisa, I. | N/A | Impacts of Cell Ranger versions on Chromium gene expression data | |
| chrna3 调节斑马鱼对酒精的反应 | Raine, J. | N/A | chrna3 modulates alcohol response in zebrafish | |
| 水体积、生物学重复和PCR重复影响深海浮游鱼类群落的特征化。 | Peres, P. A. | N/A | Water volume, biological and PCR replicates influence the characterization of deep-sea pelagic fish communities. | |
| 高分辨率活体内运动学追踪与可注射荧光纳米颗粒 | Ulutas, E. Z. | N/A | High-resolution in vivo kinematic tracking with injectable fluorescent nanoparticles | |
| 用泛扩展显微镜可视化核孔复合物的可塑性 | Morgan, K. J. | N/A | Visualizing nuclear pore complex plasticity with Pan-Expansion Microscopy | |
| 母体脂联素恢复了暴露于宫内母体肥胖的成年后代阻力血管中的胆碱能血管舒张 | Murphy, M. | N/A | Maternal adiponectin restores cholinergic vasodilation in resistance vessels from adult offspring exposed to maternal obesity in utero | |
| 凝聚素介导的染色质重塑调控传统树突状细胞的分化和功能 | Adams, N. M. | N/A | Cohesin-mediated chromatin remodeling controls the differentiation and function of conventional dendritic cells | |
| 一种宿主导向的佐剂能够复苏并增强抗生素对胞内细菌持留菌的敏感性。 | Lu, K.-Y. | N/A | A host-directed adjuvant resuscitates and sensitizes intracellular bacterial persisters to antibiotics | |
| 鉴定单性异体和雌雄同体海洋鱼类物种中性二型循环微小RNA。 | Geffroy, B. | N/A | Identifying sexually dimorphic circulating microRNAs in gonochoristic and hermaphroditic marine fish species. | |
| Prefoldin 5 是一种与微管相关的蛋白质，能够抑制Tau蛋白的聚集及其引发的神经毒性。 | Bisht, A. | N/A | Prefoldin 5 is a microtubule-associated protein that suppresses Tau-aggregation and neurotoxicity | |
| 在古菌中由机械压缩触发的类组织多细胞发育 | Rados, T. | N/A | Tissue-Like Multicellular Development Triggered by Mechanical Compression in Archaea | |
| 在自然视觉过程中，人类视觉皮层早期的反应最好由扫视（saccade）的开始而不是注视（fixation）的开始来解释。 | Amme, C. | N/A | Saccade onset, not fixation onset, best explains early responses across the human visual cortex during naturalistic vision | |
| 热中性环境对小鼠MASLD严重程度、肝基因表达及β3-肾上腺素能刺激下BAT激活的影响 | Martin, C. M. | N/A | Effect of thermoneutral housing on MASLD severity, hepatic gene expression, and BAT activation during β3-adrenergic stimulation in mice | |
| HP1/Swi6的磷酸化减轻了其与Suv39/Clr4在核小体上的竞争，并促进了H3K9三甲基化的扩展。 | Kennedy, D. R. | N/A | Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading. | |
| 在视觉引导的运动过程中，细胞类型特异性纹状体集合活动的动态失衡。 | Fearey, B. | N/A | Dynamic imbalances in cell-type specific striatal ensemble activity during visually guided locomotion. | |
| 利用表达引导性抗菌肽（gAMP）的生物工程益生菌对肿瘤相关微生物F. nucleatum进行靶向治疗 | Choudhury, A. | N/A | Targeted therapy of oncomicrobe F. nucleatum with bioengineered probiotic expressing guided antimicrobial peptide (gAMP) | |
| 针对肿瘤相关微生物具核梭杆菌（F. nucleatum）的靶向治疗：利用生物工程益生菌表达引导性抗菌肽（gAMP） | Choudhury, A. | N/A | Targeted therapy of oncomicrobe F. nucleatum with bioengineered probiotic expressing guided antimicrobial peptide (gAMP) | |
| 网格蛋白非依赖性内吞作用和癌细胞中的逆向运输促进了细胞毒性CD8 T细胞的激活。 | Xu, S. | N/A | Clathrin-independent endocytosis and retrograde transport in cancer cells promote cytotoxic CD8 T cell activation | |
| 对纯种赛马髁部应力骨折风险评估的虚拟力学测试流程进行调整与验证 | Irandoust, S. | N/A | Tuning and validation of a virtual mechanical testing pipeline for condylar stress fracture risk assessment in Thoroughbred racehorses | |
| LIMPACAT：利用全切片成像的肝癌免疫预测多组学注意力变压器 | Chiu, Y. J. | N/A | LIMPACAT：Multi-Omics Attention Transformer for Immune Prediction in Liver Cancer Using Whole-Slide Imaging | |
| 渴望联系：探索印度家庭中孕期渴望、母亲健康与儿童偏好之间的关系 | Kruthi, M. N. | N/A | Craving Connections: Exploring the Relationship Between Pregnancy Cravings, Maternal Health, and Child Preferences in Indian Families | |
| 评估尼日利亚技术学院学生生物学能力与性别及生物学成绩的关系 | Sowunmi, K. | N/A | Assessing Technical College Students' Biology Proficiency as Related to Gender and Performance in Biology in Nigeria | |
| 肺腺癌患者肿瘤引流静脉中循环细胞外囊泡的新型蛋白质组学特征 | Tricard, J. | N/A | New proteomic signature in circulating extracellular vesicles from tumor-draining vein of lung adenocarcinomas patients | |
| 肝病变动态的个体患者数据分析：泛癌分析 | Dickinson, J. | N/A | Individual Patient Data Analysis of Liver Lesion Dynamics: A Pan Cancer Analysis | |
| 双侧初级运动皮层上的双站点经颅交流电刺激增加半球间抑制并改善双手灵巧性：一项三盲、随机、假刺激对照研究 | Lebihan, B. | N/A | Dual-site transcranial alternating current stimulation over the primary motor cortices increases interhemispheric inhibition and improves bimanual dexterity: A triple-blind, randomised, sham-controlled study | |
| 小脑性伸臂共济失调对运动学和动力学需求的敏感性 | Oh, K. | N/A | Sensitivity of Cerebellar Reaching Ataxia to Kinematic and Dynamic Demands | |
| CYK-4 GAP结构域调节中心纺锤体向皮质区的定位，以促进收缩环的组装并促进环的溶解 | Schlientz, A. J. | N/A | The CYK-4 GAP domain regulates cortical targeting of centralspindlin to promote contractile ring assembly and facilitate ring dissolution | |
| 探索外泌体的粘附特性以用于功能性检测 | Pachane, B. C. | N/A | Exploring the adhesion properties of extracellular vesicles for functional assays | |
| 野生捕获的洞穴鱼睡眠损失的系统发育图谱 | North, O. | N/A | Phylogenetic mapping of sleep loss in wild-caught cavefish | |
| 双目竞争的意象启动并不是衡量个体在视觉化主观生动性方面差异的可靠指标。 | Bouyer, L. | N/A | Imagery priming of binocular rivalry is not a reliable metric of individual differences in the subjective vividness of visualisations. | |
| 利用运动学时间序列数据的神经网络分析识别中风后和神经正常步态行为的独特亚型 | Kuch, A. | N/A | Identification of distinct subtypes of post-stroke and neurotypical gait behaviors using neural network analysis of kinematic time series data | |
| 军事野外训练前后手部和前臂皮肤细菌群落动态变化 | Glenna, S. | N/A | Skin bacterial community dynamics of hands and forearms before and after military field exercise | |
| 白细胞通过内皮膜隧道渗出血管 | van der Meer, W. | N/A | Leukocytes use endothelial membrane tunnels to extravasate the vasculature | |
| N-Myc下游调控基因-1调控整合素表达以抑制胃癌转移的机制 | Wang, T. | N/A | Mechanism of N-Myc Downstream Regulated Gene-1 regulating Integrin expression to inhibit gastric cancer metastasis | |
| PET微塑料增加了胰岛素抵抗和胰腺炎的风险 | Mierzejewski, K. | N/A | PET microplastics increase the risk of insulin resistance and pancreatitis | |
| 苯并噁嗪途径与玉米硼稳态的关联 | Chu, L. | N/A | Association of the benzoxazinoid pathway with boron homeostasis in maize | |
| 向日葵HaHB4基因在现代小麦中的渐渗：应对气候变化抗逆性提升的一项进展 | Ayala, F. | N/A | Introgression of the sunflower HaHB4 gene in modern wheat: An advancement in resilience to deal with climate change | |
| 双侧颅内电磁刺激顶下小叶-海马网络增强人类长期记忆 | Borghi, I. | N/A | Dual transcranial electromagnetic stimulation of the precuneus-hippocampus network boosts human long-term memory | |
| 一种新型早发性脊髓小脑共济失调13号BAC小鼠模型，具有小脑发育不全、震颤和共济失调步态 | Yin, J. | N/A | A Novel Early Onset Spinocerebellar Ataxia 13 BAC Mouse Model with Cerebellar Hypoplasia, Tremor, and Ataxic Gait | |
| 系统性炎症和淋巴细胞活化先于类风湿性关节炎 | He, Z. | N/A | Systemic inflammation and lymphocyte activation precede rheumatoid arthritis | |
| 灭绝涡旋的驱动更多地源于有益突变的匮乏，而非有害突变的积累。 | Mawass, W. | N/A | Extinction vortices are driven more by a shortage of beneficial mutations than by deleterious mutation accumulation | |
| 病毒感染中祖细胞的基因组分析表明，糖皮质激素抑制了浆细胞样树突状细胞的生成 | Jo, Y. | N/A | Genomic Analysis of Progenitors in Viral Infection Implicates Glucocorticoids as Suppressors of Plasmacytoid Dendritic Cell Generation | |
| 中等剂量辐射会损害长期造血干细胞功能，并影响对细胞毒性应激的造血恢复。 | Zhang, Q. | N/A | Medium-dose irradiation impairs long-term hematopoietic stem cell functionality and hematopoietic recovery to cytotoxic stress | |
| Ta3N5诱导U2OS人类癌细胞凋亡 | Nozaki, T. | N/A | Induction of cell death in U2OS human cancer cells by Ta3N5 | |
| 硅胶表面上的免疫细胞死亡会驱动生物膜的形成。 | Jagirdar, S. K. | N/A | Immune cell death on silicone surfaces drives biofilm formation | |
| 探索胶质瘤细胞和细胞外囊泡中的N6-甲基腺苷及长链转录本。 | Batool, S. M. | N/A | Exploring N6-Methyladenosine and long transcripts in glioma cells and extracellular vesicles. | |
| 比较时空单细胞转录组揭示了C4禾本科植物中克朗兹解剖结构出现期间现有调控的重塑 | Zhao, C. | N/A | Comparative spatiotemporal single cell transcriptomes reveal rewiring of pre-existing regulations during emergence of Kranz anatomy in C4 grasses | |
| 受影响力数据驱动的科学推理：重振dfstat！ | Spiess, A. N. | N/A | Scientific reasoning driven by influential data: resuscitate dfstat! | |
| 早期职业研究（ECR）中导师-学员关系的调查：对STEMM学科发表和职业发展的启示 | Lordan, R. | N/A | A survey of the mentor-mentee relationship in early career research (ECR): Implications for publishing and career advancement in the STEMM disciplines | |
| 将产前和围产期风险因素与儿童皮质结构的多变量融合联系起来 | Lindseth, L. R. | N/A | Linking Pre- and Perinatal Risk Factors to a Multivariate Fusion of Child Cortical Structure | |
| Salinispora中酮霉素类似物的结构解析、生物合成基因簇分布及生物活性 | Castro-Falcon, G. | N/A | Structure elucidation, biosynthetic gene cluster distribution, and biological activities of ketomemicin analogs in Salinispora | |
| 生物衰老的标志、机制和指标：范围综述 | Ziesel, A. | N/A | Markers, Mechanisms and Metrics of Biological Aging: A Scoping Review | |
| 分层分析将HIF-2α确定为高度免疫浸润性黑色素瘤的治疗靶点。 | Huang, A. Y. | N/A | Stratified analysis identifies HIF-2α as a therapeutic target for highly immune-infiltrated melanomas | |
| 针对SARS-CoV-2变种的中和纳米抗体的深度生成设计 | Huo, L. | N/A | Deep generative design of neutralizing nanobodies againstSARS-CoV-2 variants | |
| 从菠萝（Ananas comosus）中分离出的果胶酶细菌，命名为Dickeya ananae sp. nov. | Dobhal, S. | N/A | Dickeya ananae sp. nov., pectinolytic bacterium isolated from pineapple (Ananas comosus) | |
| 奈妥匹坦对结核分枝杆菌持留菌表现出强效活性 | Eldesouky, H. E. | N/A | Netupitant Exhibits Potent Activity on Mycobacterium tuberculosis Persisters | |
| 一种垂直和水平传播的RNA病毒促进寄生蜂卵的孵化 | Izraeli, Y. | N/A | A Vertically and Horizontally Transmitted RNA Virus Facilitates Egg Hatching of a Parasitoid Wasp | |
| 在深海中，SAR11谱系的序列离散物种的形成基础是随机且无偏好的重组。 | Zhao, J. | N/A | Promiscuous and unbiased recombination underlies the sequence-discrete species of the SAR11 lineage in the deep ocean | |
| 鉴定JC多瘤病毒中的新型环状转录本 | Iida, S. | N/A | Identification of novel wraparound transcripts in JC polyomavirus | |
| 微管蛋白样蛋白CetZ1和CetZ2在古菌Haloferax volcanii的细胞形态发生中起协调作用 | Brown, H. J. | N/A | Tubulin-like proteins CetZ1 and CetZ2 coordinate cellular morphogenesis in the archaeon Haloferax volcanii | |
| 由以厌氧甲烷氧化古菌（ANME archaea）为主导的共生体从烃类物质中产生甲烷 | Sarno, N. | N/A | Methane production from hydrocarbons by consortia dominated by ANME archaea | |
| RNA外切体通过调控大脑中转录本的丰度来维持细胞RNA稳态。 | Higginson, L. A. | N/A | The RNA exosome maintains cellular RNA homeostasis by controlling transcript abundance in the brain | |
| 蜻蜓分子系统发育研究的新标记，包括保守组蛋白H3和H4基因的部分及它们之间的间隔区 | Mglinets, A. V. | N/A | A new marker for molecular phylogenetic studies in Odonata including parts of conservative histone H3 and H4 genes and spacer between them | |
| 组蛋白乙酰转移酶p300对RORβ的乙酰化以及SIRT1的去乙酰化作用，调节了受体的稳定性、更新速率及转录活性。 | O'Leary, T. R. | N/A | Acetylation of RORβ by lysine acetyltransferase p300 and deacetylation by SIRT1 modulates receptor stability, turnover and transcriptional activity. | |
| RNA聚合酶I转录起始效率及起始位点选择的决定因素 | Parilova, O. | N/A | Determinants of transcription initiation efficiency and start site selection by RNA polymerase I | |
| 静电相互作用决定了纳库巴坦对OXA-48样β-内酰胺酶的效能 | Hoff, J. F. | N/A | Electrostatic interactions define nacubactam potency against OXA-48-like β-lactamases | |
| 体内特定部位的UFMylome定量分析揭示了肌球蛋白在ALS中的修饰 | Blazev, R. | N/A | Site-specific quantification of the in vivo UFMylome reveals myosin modification in ALS | |
| 自文档化质粒 | Peccoud, S. J. | N/A | Self-Documenting Plasmids | |
| 长上下文蛋白质语言模型 | Wang, Y. | N/A | Long-context Protein Language Model | |
| 一种基于大肠杆菌染色体的动态三维聚合物模型，由光学组合筛选的数据驱动。 | Schirman, D. | N/A | A dynamic 3D polymer model of the Escherichia coli chromosome driven by data from optical pooled screening | |
| 噬菌体CRISPR样调控RNA抑制细菌的适应性和先天免疫 | Liu, C. | N/A | Phage CRISPR-like regulatory RNAs silence bacterial adaptive and innate immunity | |
| 全基因组抗生素-CRISPRi分析揭示了将LiaR激活作为恢复氟喹诺酮耐药性肺炎链球菌敏感性策略的发现 | Sewgoolam, B. | N/A | Genome-wide antibiotic-CRISPRi profiling identifies LiaR activation as a strategy to resensitize fluoroquinolone-resistant Streptococcus pneumoniae | |
| 可咀嚼的鼠李糖乳杆菌GG在鼻腔内定植，并促进过敏性鼻结膜炎患者的局部免疫益处 | De Boeck, I. | N/A | Lacticaseibacillus rhamnosus GG in a chewable colonizes the nose and facilitates local immune benefits in allergic rhinoconjunctivitis patients | |
| 磷酸盐改良剂在土壤湿润后促使RNA病毒大量繁殖 | Sieradzki, E. T. | N/A | Phosphate amendment drives bloom of RNA viruses after soil wet-up | |
| 温和链球菌糖脂的生物合成及其在生理和抗生素敏感性中的作用 | Wei, Y. | N/A | Biosynthesis of mitis group streptococcal glycolipids and their roles in physiology and antibiotic susceptibility | |
| 外源性脂肪酸通过在磷脂合成中与内源性和外源性生成的底物之间的竞争，抑制了大肠杆菌中的脂肪酸合成。 | van den Berg, S. P. H. | N/A | Exogenous fatty acids inhibit fatty acid synthesis through competition between endogenously- and exogenously-generated substrates for phospholipid synthesis in Escherichia coli | |
| 增强型Nme2Cas9和Nme2SmuCas9核酸酶及碱基编辑器的合理设计 | Bamidele, N. | N/A | Rational Design of Enhanced Nme2Cas9 and Nme2SmuCas9 Nucleases and Base Editors | |
| SeqTagger，一个快速且精准的工具，用于解复用直接RNA纳米孔测序数据集 | Pryszcz, L. P. | N/A | SeqTagger, a rapid and accurate tool to demultiplex direct RNA nanopore sequencing datasets | |
| 一种组合域筛选平台揭示了转录扰动中的表观遗传效应物相互作用 | Moon, H. C. | N/A | A combinatorial domain screening platform reveals epigenetic effector interactions for transcriptional perturbation | |
| 单纯疱疹病毒1型起源结合蛋白UL9通过分子内和分子间的方式将起源DNA和非起源DNA连接和环化。 | Meier, A. F. | N/A | Herpes simplex virus type 1 origin binding protein UL9 tethers and loops origin- and non-origin-DNA intra- and intermolecularly | |
| 在ORC缺陷细胞中选择性起源和MCM2-7功能的过度加载。 | Shibata, Y. | N/A | Specific origin selection and excess functional MCM2-7 loading in ORC-deficient cells. | |
| 滑膜成纤维细胞中的O-糖基化驱动软骨降解 | Tran, L. S. | N/A | ER O-glycosylation in synovial fibroblasts drives cartilage degradation | |
| 人类精子发生导致核孔结构和功能的减少 | dos Santos, A. | N/A | Human spermatogenesis leads to a reduced nuclear pore structure and function | |
| 复合素2在调节胰岛郎格汉斯细胞激素分泌中的作用 | Ng, X. W. | N/A | Role of Complexin 2 in the regulation of hormone secretion from the islet of Langerhans | |
| 神经元和星形胶质细胞具有不同的细胞器特征和应激反应。 | Rhoads, S. N. | N/A | Neurons and astrocytes have distinct organelle signatures and responses to stress | |
| AlphaFold 2，而非AlphaFold 3，能够预测出对重复蛋白质具有高度信心但不切实际的beta-螺旋结构。 | Pratt, O. S. | N/A | AlphaFold 2, but not AlphaFold 3, predicts confident but unrealistic beta-solenoid structures for repeat proteins | |
| 用于土壤真菌间细胞通讯多重筛选的综合平台 | Schiesaro, G. | N/A | A synthetic platform for multiplex screening of cell-cell communication between soil fungi | |
| TXNIP通过介导LAT1/SLC7A5的内吞作用，减少进入静止状态的细胞对氨基酸的摄取。 | Kahlhofer, J. | N/A | TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence | |
| # BioRxiv 2024-10-29 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 将新的视觉类别雕刻进人类大脑 | Iordan, C. R. | N/A | Sculpting New Visual Categories into the Human Brain | |
| 秀丽隐杆线虫中双链RNA的跨代运输可以限制可遗传的表观遗传变化 | Shugarts, N. | N/A | Intergenerational transport of double-stranded RNA in C. elegans can limit heritable epigenetic changes | |
| 沙门氏菌诱导的SIRT1和SIRT3对于维持细菌和宿主的代谢转换至关重要，以实现成功的致病过程。 | Hajra, D. | N/A | Salmonella-induced SIRT1 and SIRT3 are crucial for maintaining the metabolic switch in bacteria and host for successful pathogenesis | |
| 将中风后手臂瘫痪中的移动和保持控制分开 | Hadjiosif, A. M. | N/A | Separating the control of moving and holding in post-stroke arm paresis | |
| 阿米巴样细胞在软端极化的NMIIA作用下进行硬度趋向性运动。 | Kang, C. | N/A | Amoeboid cells undergo durotaxis with soft end polarized NMIIA | |
| 系统性忽视与对变化过度和不足反应的神经计算基础 | Wang, M.-C. | N/A | System Neglect and the Neurocomputational Substrates for Over- and Underreactions to Change | |
| 检测政权更迭：对变化过度反应和反应不足的神经计算基础 | Wang, M.-C. | N/A | Detecting Regime Shifts: Neurocomputational Substrates for Over- and Underreactions to Change | |
| 上皮微侵袭与由疾病减毒肺炎球菌生物合成基因突变体引发的免疫反应 | Weight, C. M. | N/A | Epithelial microinvasion and immunity elicited by disease-attenuated pneumococcal biosynthesis gene mutants | |
| 居留-殖民权衡与生态位分化使得大肠杆菌的多个谱系能在健康人体中共存 | Morel-Journel, T. | N/A | Residence-colonization trade-off and niche differentiation enable the coexistence of Escherichia coli phylogroups in healthy humans | |
| Cell2Sentence：教授大型语言模型生物学的语言 | Levine, D. | N/A | Cell2Sentence: Teaching Large Language Models the Language of Biology | |
| TgLaforin，一种葡聚糖磷酸酶，揭示了储存多糖在刚地弓形虫速殖子和缓殖子中的动态作用。 | Murphy, R. D. | N/A | TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in Toxoplasma gondii tachyzoites and bradyzoites | |
| DetectEV：一种用于评估细胞外囊泡完整性和生物活性的功能性酶学检测方法 | Adamo, G. | N/A | DetectEV: a functional enzymatic assays to assess integrity and bioactivity of extracellular vesicles | |
| 通过水平基因转移获得的基因在Photorhabdus laumondii中具有共同的调控模式。 | Rili, L. | N/A | Genes acquired by horizontal gene transfer share common regulatory patterns in Photorhabdus laumondii | |
| 结合进化和蛋白质语言模型，利用D2Deep实现可解释的癌症驱动突变预测 | Tzavella, K. | N/A | Combining evolution and protein language models for an interpretable cancer driver mutation prediction with D2Deep | |
| 体积电子显微镜揭示了人类内嗅皮层中独特的层状突触特性 | Plaza-Alonso, S. | N/A | Volume Electron Microscopy Reveals Unique Laminar Synaptic Characteristics in the Human Entorhinal Cortex | |
| 新型神经启发式控制器通过内部模型在低级肢体任务中实现了模块化泛化 | Munoz, D. | N/A | New neural-inspired controller generalises modularity over lower limb tasks through internal models | |
| behaviorMate：一种基于物联网的方法，用于适应性控制行为和基于导航的实验 | Bowler, J. C. | N/A | behaviorMate: An Intranet of Things Approach for Adaptable Control of Behavioral and Navigation-Based Experiments | |
| 无偏倚地识别密集混合神经元培养物中的细胞身份 | De Beuckeleer, S. | N/A | Unbiased identification of cell identity in dense mixed neural cultures | |
| 果蝇神经元类型的分裂GAL4驱动线资源 | Meissner, G. W. | N/A | A split-GAL4 driver line resource for Drosophila neuron types | |
| 通过MALDI-TOF MS自动网络化录入艰难梭菌的核糖型 | Sanchez-Blazquez, M. | N/A | Automated web-based typing of Clostridioides difficile ribotypes via MALDI-TOF MS | |
| GSK3抑制改善了纽芬兰ACM患者iPSC-心肌细胞的异常收缩能力 | Noort, R. J. | N/A | GSK3 inhibition ameliorates the abnormal contractility of Newfoundland ACM patient iPSC-cardiomyocytes | |
| Omicron谱系BA.1、BA.2、BA.5.1、BQ.1、XBB.1.5、EG.5.1和JN.1.1的免疫逃逸和复制能力 | Bekliz, M. | N/A | Immune escape and replicative capacity of Omicron lineages BA.1, BA.2, BA.5.1, BQ.1, XBB.1.5, EG.5.1 and JN.1.1 | |
| 探索自噬蛋白LC3B和GABARAP的芳基亚甲基-吲哚酮配体 | Leveille, A. N. | N/A | Exploring Arylidene-Indolinone Ligands of Autophagy Proteins LC3B and GABARAP | |
| 观察气孔活动：在植物体内自主成像单个气孔运动 | van den Berg, T. E. | N/A | Viewing stomata in action: Autonomous in planta imaging of individual stomatal movement | |
| 选择性激动GPR34可刺激小胶质细胞摄取和清除β淀粉样纤维 | Etani, H. | N/A | Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils | |
| 撤回：噬菌体与抗生素在减少铜绿假单胞菌生物膜中的协同作用 | Timilsina, S. | N/A | WITHDRAWN: SYNERGISM OF BACTERIOPHAGE AND ANTIBIOTICS IN THE REDUCTION of Pseudomonas aeruginosa biofilm | |
| 癌症中通过体细胞突变破坏肿瘤抑制基因的剪接和多聚腺苷酸化信号 | Kainov, Y. | N/A | Recurrent disruption of tumour suppressor genes in cancer by somatic mutations in cleavage and polyadenylation signals | |
| 我的朋友MIROSLAV：一个可破解的开源硬件和软件平台，用于在家笼中进行高通量啮齿动物活动监测 | Virag, D. | N/A | My friend MIROSLAV: A Hackable Open-Source Hardware and Software Platform for High-Throughput Rodent Activity Monitoring in the Home Cage | |
| 前额叶和感觉皮层中的预备性注意模板编码了与目标相关的信息 | Zhou, Z. | N/A | Preparatory attentional templates in prefrontal and sensory cortex encode target-associated information | |
| 从电子表格实验室数据模板到知识图谱：抗微生物药物耐药性研究领域中的FAIR数据之旅 | Gadiya, Y. | N/A | From spreadsheet lab data templates to knowledge graphs: A FAIR data journey in the domain of AMR research | |
| 通过卡尔曼滤波提高了全身质心位置的准确性 | Le Mouel, C. | N/A | Improved accuracy of the whole body Center of Mass position through Kalman filtering | |
| 12-脂氧合酶抑制延缓人基因替代小鼠自身免疫性糖尿病的发作 | Nargis, T. | N/A | 12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice | |
| 级联反向积分反馈以增强稳定性和性能 | M. Zand, A. | N/A | Cascaded Antithetic Integral Feedback for Enhanced Stability and Performance | |
| 利用单组分融合蛋白在酿酒酵母中对磷酸盐应答基因进行光遗传学控制 | Cleere, M. M. | N/A | Optogenetic control of phosphate-responsive genes using single component fusion proteins in Saccharomyces cerevisiae | |
| 评估基于排列的推断在神经影像数据偏最小二乘分析中的应用 | Danyluik, M. | N/A | Evaluating permutation-based inference for partial least squares analysis of neuroimaging data | |
| 撤回：一种可溶性膳食纤维和矿物质配方对餐后血糖调节和饱腹感的初步研究。 | haynes, m. m. | N/A | WITHDRAWN: A preliminary investigation of a soluble dietary fibre and mineral formulation on post-prandial glucose regulation and satiation. | |
| 湿地石楠林的生态系统动力学：环境驱动因素对植被的空间和时间效应 | Damgaard, C. | N/A | Ecosystem dynamics in wet heathlands: spatial and temporal effects of environmental drivers on the vegetation | |
| 评估模型设定和先验敏感性对贝叶斯时间信号检验的影响 | Tay, J. H. | N/A | Assessing the effect of model specification and prior sensitivity on Bayesian tests of temporal signal | |
| 配体介导的内吞作用在活体骨细胞中以一种性别二态性的方式受到调控 | Matthews, M. D. | N/A | Ligand-Mediated Endocytosis Is Regulated in a Sexually Dimorphic Way in Osteocytes in vivo | |
| 神经反馈训练期间反馈处理和调节重新校准的神经机制 | Pamplona, G. S. P. | N/A | Neural Mechanisms of Feedback Processing and Regulation Recalibration during Neurofeedback Training | |
| 竞争和频率依赖性共同决定了沙丘石楠生态系统的群落动态 | Damgaard, C. | N/A | Both competition and frequency-dependence determine community dynamics in a dune heath ecosystem | |
| 一项关于不同土壤类型和地理区域抗生素抗性基因的宏基因组研究 | Pillay, S. | N/A | A Metagenomic Study of Antibiotic Resistance Across Diverse Soil Types and Geographical Locations | |
| 甲基组揭示了两种植物物种种群中最近的进化变化 | Korfmann, K. | N/A | Methylomes reveal recent evolutionary changes in populations of two plant species | |
| 大规模衰老：来自狗衰老项目的年轻狗和大型品种显示出加速的表观遗传衰老。 | McCoy, B. M. | N/A | Aging at scale: Younger dogs and larger breeds from the Dog Aging Project show accelerated epigenetic aging. | |
| 小锚蛋白重复蛋白（Ankyrons）对SARS-CoV-2变种的功能活性及结合特异性研究。 | Park, Y.-J. | N/A | Functional Activity and Binding Specificity of small Ankyrin Repeat Proteins called Ankyrons against SARS-CoV-2 variants. | |
| 小血管脑病遗传决定因子TRIM47通过NRF2抗氧化系统调控脑稳态 | Duplaa, C. | N/A | Cerebral Small Vessel Disease genetic determinant TRIM47 controls brain homeostasis via the NRF2 antioxidant system | |
| UniScore是一种通过多重搜索引擎对肽段鉴定进行统一和普遍评估的指标。 | Tabata, T. | N/A | UniScore, a unified and universal measure for peptide identification by multiple search engines | |
| 微生物组知识图谱（MicrobiomeKG）：通过知识图谱连接微生物组研究与宿主健康 | Goetz, S. L. | N/A | MicrobiomeKG: Bridging Microbiome Research and Host Health Through Knowledge Graphs | |
| 活性氧解毒作用有助于脓肿分枝杆菌的抗生素存活 | Bates, N. A. | N/A | Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival | |
| 进化宏观生态学：在基于过程的、前向时间模拟模型中更明确地纳入系统发育信息 | Culshaw, V. | N/A | Evolutionary macroecology: Incorporating phylogenetic information more explicitly into process-based, forward time, simulation models | |
| 真菌性脑膜炎病原体的表型景观揭示了其独特的生物学特性 | Boucher, M. | N/A | Phenotypic landscape of a fungal meningitis pathogen reveals its unique biology | |
| 结核菌噬菌体毒力比较研究 | Rubino, I. | N/A | Comparative study on the virulence of mycobacteriophages | |
| 通过流形再现分析进行生成模型的验证 | Lazzaro, N. | N/A | Generative Models Validation via Manifold Recapitulation Analysis | |
| Neuroligin 3 突显了果蝇社交距离中的性别二态性电路 | Robinson, J. W. | N/A | Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing | |
| LYCEUM：学习在低覆盖率的古代基因组中识别拷贝数变异 | Yilmaz, M. | N/A | LYCEUM: Learning to call copy number variants on low coverage ancient genomes | |
| LYCEUM：学习在低覆盖率的古代基因组中识别拷贝数变异 | Yilmaz, M. A. | N/A | LYCEUM: Learning to call copy number variants on low coverage ancient genomes | |
| 伏隔核抑制性中间神经元表达的μ阿片受体促进亲和社交行为 | Toddes, C. | N/A | Mu opioid receptor expression by nucleus accumbens inhibitory interneurons promotes affiliative social behavior | |
| 细胞基因组的表观遗传限制在进化上将遗传变异与功能联系起来。 | Sinniah, E. | N/A | Epigenetic constraint of cellular genomes evolutionarily links genetic variation to function | |
| 普遍且反复的杂交现象防止了欧洲最受威胁的海鸟近亲繁殖的衰退 | Izquierdo-Aranega, G. | N/A | Pervasive and recurrent hybridisation prevents inbreeding depression in Europe's most threatened seabird | |
| 活动依赖性的细胞外蛋白水解级联反应重塑细胞外基质以促进结构可塑性 | Singh, J. B. | N/A | Activity-dependent extracellular proteolytic cascade remodels ECM to promote structural plasticity | |
| 广泛存在的适应性权衡现象：通过快速适应在大型实验种群中揭示的果蝇（Drosophila melanogaster） | Bitter, M. C. | N/A | Pervasive fitness trade-offs revealed by rapid adaption in large experimental populations of Drosophila melanogaster | |
| 通过快速适应在大规模实验种群中揭示的普遍性适应性权衡——果蝇黑腹果蝇 | Bitter, M. C. | N/A | Pervasive fitness trade-offs revealed by rapid adaptation in large experimental populations of Drosophila melanogaster | |
| 马拉维湖慈鲷中的大倒位与栖息地偏好、谱系和性别决定有关 | Kumar, N. M. | N/A | Large inversions in Lake Malawi cichlids are associated with habitat preference, lineage, and sex determination | |
| 在实验性假单胞菌（Pseudomonas aeruginosa）的元种群中，快速适应和增强的遗传平行性 | Chakraborty, P. | N/A | Rapid adaptation and increased genetic parallelism in experimental metapopulations of Pseudomonas aeruginosa | |
| 在秀丽隐杆线虫中Argonaute基因家族功能谱系的动态产生与消亡 | Fusca, D. D. | N/A | Dynamic birth and death of Argonaute gene family functional repertoire across Caenorhabditis nematodes | |
| DeepRNA-Twist：基于语言模型引导的RNA扭转角预测与注意力-初始网络 | Abir, A. R. | N/A | DeepRNA-Twist: Language Model guided RNA Torsion Angle Prediction with Attention-Inception Network | |
| 一种利用化学交联的蛋白质整合对接的新型离散几何方法 | Zhang, Y. | N/A | A new discrete-geometry approach for integrative docking of proteins using chemical crosslinks | |
| 解析Musashi-1对RNA的识别，以设计用于体外和体内应用的蛋白质和RNA突变体 | Perez-Rafols, A. | N/A | Deciphering the RNA recognition by Musashi-1 to design protein and RNA mutants for in vitro and in vivo applications | |
| SPONGE：简单先验组学网络生成器 | Hovan, L. | N/A | SPONGE: Simple Prior Omics Network GEnerator | |
| 捕获单分子性质并不能确保生物分子相图的准确预测 | Feito, A. | N/A | Capturing single-molecule properties does not ensure accurate prediction of biomolecular phase diagrams | |
| 来自NOD和NOR小鼠的血清及泪液自身抗体作为Sjögren's病局部和系统性炎症潜在的诊断指标 | Kakan, S. S. | N/A | Serum and Tear Autoantibodies from NOD and NOR Mice as Potential Diagnostic Indicators of Local and Systemic Inflammation in Sjögren's Disease | |
| 通过单细胞RNA测序数据解析人肝第I组ILC的异质性和肿瘤相关动态 | Zhang, Y. | N/A | Dissecting the Heterogeneity and Tumor-Associated Dynamics of Human Liver Group I ILC via scRNA Sequencing Data | |
| 中译：产婆蟾（Alytes）物种形成中的基因组、表型和环境相关性 | Ambu, J. | N/A | Genomic, phenotypic and environmental correlates of speciation in the midwife toads (Alytes) | |
| 减数分裂驱动的代谢成本 | Bradshaw, S. L. | N/A | The metabolic costs of meiotic drive | |
| 从大量组织表达数据推断基因调控的局限性 | Chu, C. P. | N/A | Limits to the inference of gene regulation from bulk tissue expression data | |
| V-和VL-评分揭示蛋白质家族的病毒特征和起源 | Zhou, K. | N/A | V- and VL-Scores Uncover Viral Signatures and Origins of Protein Families | |
| 脂质分层降低高曲率囊泡出芽的能垒 | Schachter, I. | N/A | Lipid Demixing Reduces Energy Barriers for High Curvature Vesicle Budding | |
| 对帕金森病相关α-突触核蛋白的核内作用结构和功能的新认识 | Jos, S. | N/A | Structural and functional insights into nuclear role of Parkinson's Disease-associated α-Synuclein | |
| IL-13/IL-13Rα2轴促进血管肉瘤细胞的增殖 | Saito, H. | N/A | IL-13/IL-13Rα2 axis promotes proliferation of angiosarcoma cells | |
| CIGB-300逆转了MDR1转染的肺鳞状癌细胞的化疗耐药性。 | Wang, M. | N/A | CIGB-300 reverses chemo-resistance in MDR1-transfected lung squamous cancer cells | |
| 铜绿假单胞菌代谢物3-酮基-C12HSL通过T2R14和线粒体钙单向转运体诱导细胞凋亡 | Miller, Z. A. | N/A | Pseudomonas aeruginosa metabolite 3-oxo-C12HSL induces apoptosis through T2R14 and the mitochondrial calcium uniporter | |
| 降低肝脏线粒体能量代谢会损害胃预负荷和禁食后的食物摄入调控 | Ponte, M. E. | N/A | Reduced Liver Mitochondrial Energy Metabolism Impairs Food Intake Regulation Following Gastric Preloads and Fasting | |
| 降低肝脏线粒体能量代谢会损害胃预充填和禁食后的食物摄入调控 | Ponte, M. E. | N/A | Reduced Liver Mitochondrial Energy Metabolism Impairs Food Intake Regulation Following Gastric Preloads and Fasting | |
| 脂肪细胞素信号通过抑制平滑肌嘌呤能收缩性调节膀胱功能 | Luo, Z. | N/A | Adiponectin Signaling Regulates Urinary Bladder Function by Blunting Smooth Muscle Purinergic Contractility | |
| 通过膜脂重塑调控外周脂肪储存能力的饮食控制 | Tol, M. J. | N/A | Dietary control of peripheral adipose storage capacity through membrane lipid remodelling | |
| 一种肿瘤分泌的蛋白质利用胰高血糖素释放导致宿主消瘦。 | Ding, G. | N/A | A tumor-secreted protein utilizes glucagon release to cause host wasting | |
| 钙稳态反馈控制预测心房颤动的起始、重构和进展 | Moise, N. | N/A | Calcium homeostatic feedback control predicts atrial fibrillation initiation, remodeling, and progression | |
| CpGPT：一种用于DNA甲基化的基础模型 | de Lima Camillo, L. P. | N/A | CpGPT: a Foundation Model for DNA Methylation | |
| RGS10减轻慢性炎症应激引起的全身免疫失调 | Jernigan, J. E. | N/A | RGS10 Attenuates Systemic Immune Dysregulation Induced by Chronic Inflammatory Stress | |
| 工程细菌诱导的肿瘤特异性抗体促进膀胱癌免疫治疗 | Rouanne, M. | N/A | Tumor-specific antibodies elicited by engineered bacteria promote bladder cancer immunotherapy | |
| 细胞因子诱导的人巨噬细胞在体外向与阿尔茨海默病相关的分子和细胞表型重编程 | Podlesny-Drabiniok, A. | N/A | Cytokine-induced reprogramming of human macrophages toward Alzheimer's disease-relevant molecular and cellular phenotypes in vitro | |
| HP1/Swi6的磷酸化缓解了其与Suv39/Clr4在核小体上的竞争，并促进了H3K9三甲基化的扩散。 | Kennedy, D. R. | N/A | Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading. | |
| CCAFE：从GWAS汇总统计数据中估计病例和对照的等位基因频率 | Stoneman, H. R. | N/A | CCAFE: Estimating Case and Control Allele Frequencies from GWAS Summary Statistics | |
| 高风险MYCN扩增和高风险MYCN非扩增神经母细胞瘤患者的比较网络分析 | Chang, E. | N/A | A comparative network analysis of high-risk MYCN amplified and high-risk MYCN non-amplified neuroblastoma patients | |
| Hypermut 3：识别在特定核苷酸背景下允许多态性特征的具体突变模式 | Lapp, Z. | N/A | Hypermut 3: Identifying specific mutational patterns in a defined nucleotide context that allows multistate characters | |
| 非洲刺鼠（Acomys）对致癌作用的抗性与肿瘤抑制基因的上调相关。 | Vitorino, M. | N/A | Resistance to Carcinogenesis in the African Spiny Mouse (Acomys) correlates with upregulation of tumor suppressor genes. | |
| 乳铁蛋白衍生肽嵌合体诱导多发性骨髓瘤中依赖于半胱天冬酶的细胞死亡 | Jang, Y.-S. | N/A | Lactoferrin-Derived Peptide Chimera Induces Caspase-independent Cell Death in Multiple Myeloma | |
| 慢性肾脏病中改变的全身生物能量储备使心脏更易出现更差的功能结果 | Young, M. | N/A | Altered systemic bioenergetic reserve in chronic kidney disease predisposes hearts to worse functional outcomes | |
| 基于序列的TCR-肽表示：利用跨表位对比微调蛋白质语言模型 | Im, C. | N/A | Sequence-based TCR-Peptide Representations Using Cross-Epitope Contrastive Fine-tuning of Protein Language Models | |
| 纳米尺度3D DNA追踪揭示了有丝分裂染色体自我组织的机制 | Beckwith, K. S. | N/A | Nanoscale 3D DNA tracing reveals the mechanism of self-organization of mitotic chromosomes | |
| 肯尼亚西部小农玉米生产系统中农林复合种植的采用及其对土壤质量的影响 | Nyuma, H. T. | N/A | Agroforestry adoption and its influence on soil quality under smallholder maize production systems in western Kenya | |
| 基于血液DNA甲基化的年龄预测 | liu, R. | N/A | Age Prediction based on Blood DNA Methylation | |
| 使用酒石黄进行光学透明化可实现通过巩膜的深度光学相干断层扫描成像 | Narawane, A. | N/A | Optical Clearing with Tartrazine Enables Deep Transscleral Imaging with Optical Coherence Tomography | |
| 可扩展制备坚韧且可回收的孢子承载型生物复合热塑性聚氨酯 | Kim, H. S. | N/A | Scalable Fabrication of a Tough and Recyclable Spore-Bearing Biocomposite Thermoplastic Polyurethane | |
| PAV-spotter：利用信号互相关性识别目标捕获数据中的存在/缺失变异 | de Visser, M. C. | N/A | PAV-spotter: using signal cross-correlations to identify Presence/Absence Variation in target capture data | |
| 功能性便携式血液透析机XKIDNEY的评估 | Lee, J. K. | N/A | Evaluation of a Functional Portable Hemodialysis Machine, XKIDNEY | |
| 分箱与分类法的结合：TaxVAMB利用双模态变分自编码器提升宏基因组分箱效果 | Kutuzova, S. | N/A | Binning meets taxonomy: TaxVAMB improves metagenome binning using bi-modal variational autoencoder | |
| 使用PHILHARMONIC解码非模式生物的功能性相互作用网络 | Sledzieski, S. | N/A | Decoding the Functional Interactome of Non-Model Organisms with PHILHARMONIC | |
| 面向蛋白质生成模型鲁棒性评估：对度量标准的系统分析 | Strashnov, P. | N/A | Towards Robust Evaluation of Protein Generative Models: A Systematic Analysis of Metrics | |
| 蛋白质和编码序列的整合使得语言模型能够相互增强 | Zhao, H.-R. | N/A | Integration of protein and coding sequences enables mutual augmentation of the language model | |
| 用于分析力激活蛋白延伸和相互作用的DNA纳米装置 | Zhou, K. | N/A | DNA nanodevice for analysis of force-activated protein extension and interactions | |
| 单分子分析揭示了变体PRC1复合物介导的染色质泛素化机制 | Teslenko, A. | N/A | Single-molecule analysis reveals the mechanism of chromatin ubiquitylation by variant PRC1 complexes | |
| 5hmC增强PARP捕获并恢复化学抗性BRCA1/2缺陷细胞对PARP抑制剂的敏感性 | Kharat, S. S. | N/A | 5hmC enhances PARP trapping and restores PARP inhibitor sensitivity in chemoresistant BRCA1/2-deficient cells | |
| 危地马拉宫颈癌进展分析——从癌前病变到侵袭性疾病 | Robinson, E. | N/A | Analysis of the progression of cervical cancer in Guatemala- from pre-malignancy to invasive disease | |
| 苔藓植物Marchantia中组织平坦性的机械调控 | Ferria, J. | N/A | Mechanical regulation of tissue flatness in Marchantia | |
| 拟南芥氨基酸转运蛋白UmamiT20赋予对灰霉病菌的易感性。 | Prior, M. | N/A | The Arabidopsis amino acid transporter UmamiT20 confers susceptibility to B. cinerea | |
| AtTOC159受体通过β信号和位于C端的半乳糖脂特异性转运肽样序列，被靶向定位到叶绿体外膜。 | Fish, M. | N/A | AtTOC159 Receptors are Targeted to the Chloroplast Outer Membrane by a β-Signal and Galactolipid-Specific Transit Peptide-Like Sequence at the C-Terminus | |
| 对光周期的敏感性是亚麻荠（Camelina sativa）中一种复杂的性状。 | Ramirez-Corona, B. | N/A | Sensitivity to photoperiod is a complex trait in Camelina sativa | |
| 评估孟加拉国贾肖尔地区万寿菊（Tagetes erecta）栽培中田间病害的发生率和严重程度：研究结果 | Shome, A. | N/A | Assessing the Incidence and Severity of Field Diseases in Marigold (Tagetes erecta) Cultivation: Results from Jashore District, Bangladesh | |
| 利用抗原和肽特征预测细菌中的免疫原性CD4+ T细胞表位 | Marrama, D. | N/A | Predicting Immunogenic CD4+ T Cell Epitopes in Bacteria Using Antigen and Peptide Features | |
| 乳酸乳球菌乳亚种C60通过在肠道环境中对树突状细胞进行功能性修饰，促进B细胞产生免疫球蛋白A。 | Saito, S. | N/A | Lactococcus lactis subsp. cremoris C60 promotes immunoglobulin A production from B cells through functional modification of dendritic cells in intestinal environment | |
| 通过工程化共刺激受体生成具有降低脱靶交叉反应性的T细胞 | Cabezas Caballero, J. | N/A | Generation of T cells with reduced off-target cross-reactivities by engineering co-signalling receptors | |
| 由Arp2/3驱动的膜振荡在神经干细胞分裂期间收缩细胞间桥 | LaFoya, B. | N/A | Membrane oscillations driven by Arp2/3 constrict the intercellular bridge during neural stem cell divisions | |
| 新型类肝细胞肝类器官再现了关键的成熟肝功能 | Ardisasmita, A. I. | N/A | Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions | |
| 通过预测裂头绦虫（Schistocephalus solidus）的排泄/分泌蛋白和跨膜蛋白，揭示其种群间的蛋白质组分化 | Wang, A. | N/A | Among-Population Differentiation in the Tapeworm Proteome through Prediction of Excretory/Secretory and Transmembrane Proteins in Schistocephalus solidus | |
| C9orf72扩展导致不稳定的叶酸敏感性脆性位点FRA9A的形成。 | Mirceta, M. | N/A | C9orf72 expansion creates the unstable folate-sensitive fragile site FRA9A | |
| 一种由自噬基因ATG9B突变引起的新型神经发育罕见疾病的特征描述 | Kilic, S. | N/A | Characterization of a novel neurodevelopmental rare disease caused by a mutation within the autophagy gene ATG9B | |
| 鉴定用于选择燕麦冠锈病抗性的诊断性KASP标记 | Nguyen, D. T. | N/A | Identification of diagnostic KASP markers for selection of crown rust resistance in oats | |
| 潜在致病基因的概率性精细定位 | Okamoto, J. | N/A | Probabilistic Fine-mapping of Putative Causal Genes | |
| VizCNV：一个集成平台，用于同时进行三联体基因组测序数据的相位BAF和CNV分析 | Du, H. | N/A | VizCNV: An integrated platform for concurrent phased BAF and CNV analysis with trio genome sequencing data | |
| 传奇：在多模态转录组测序数据中识别共表达基因 | Deng, T. | N/A | LEGEND: Identifying Co-expressed Genes in Multimodal Transcriptomic Sequencing Data | |
| 运动意识中的运动等效性 | Fasola, J. | N/A | Motor Equivalence in Motor Awareness | |
| 基于物理的超快速大象鼻子建模 | Kaczmarski, B. K. | N/A | Ultra-fast physics-based modeling of the elephant trunk | |
| 无标记光学活检揭示了糖尿病肾脏组织的生物分子和形态学特征，包括二维和三维 | Fung, A. A. | N/A | Label-Free Optical Biopsy Reveals Biomolecular and Morphological Features of Diabetic Kidney Tissue in 2D and 3D | |
| 在循环中使用大型语言模型设计多样且高性能的蛋白质 | Gomez-Uribe, C. | N/A | Designing diverse and high-performance proteins with a large language model in the loop | |
| 突破束缚：针对肝脏的无缝整合环状AAV载体的研发 | Estes, B. J. G. | N/A | Breaking Free: Development of Circular AAV Cargos for Targeted Seamless Integration in the Liver | |
| 基于泛基因组的整数规划框架用于基因组推断 | Chandra, G. | N/A | Integer programming framework for pangenome-based genome inference | |
| SpatialPPI 2.0：通过图注意力网络中的残基间分析增强蛋白质-蛋白质相互作用预测 | Hu, W. | N/A | SpatialPPI 2.0: Enhancing Protein-Protein Interaction Prediction through Inter-Residue Analysis in Graph Attention Networks | |
| 解析人类蛋白质中内在无序性的复杂性 | de Vries, I. | N/A | Disentangling the CHAOS of intrinsic disorder in human proteins | |
| 基准测试HelixFold3预测的Holo结构用于相对自由能扰动计算 | Furui, K. | N/A | Benchmarking HelixFold3-Predicted Holo Structures for Relative Free Energy Perturbation Calculations | |
| 利用智能手机RGB影像和LiDAR点云进行增强型叶片氮素和地上生物量评估——以中国菠菜为例 | Harikumar, A. | N/A | Harnessing Smartphone RGB Imagery and LiDAR Point Cloud for Enhanced Leaf Nitrogen and Shoot Biomass Assessment - Chinese Spinach as a Case Study | |
| 从组学数据中统一知识驱动的网络推断 | Rodriguez-Mier, P. | N/A | Unified knowledge-driven network inference from omics data | |
| 利用细胞显像图像数据进行生物活性预测的半监督对比学习 | Bushiri Pwesombo, D. | N/A | Semi-supervised Contrastive Learning for Bioactivity Prediction using Cell Painting Image Data | |
| 内源性大麻素亚型选择性的动态机制 | Dutta, S. | N/A | Dynamic Mechanism for Subtype Selectivity of Endocannabinoids | |
| 解开应力纤维和未成束肌动蛋白网络对细胞形状响应的皮质张力各向异性贡献的纠缠 | Fage, F. | N/A | Disentangling the contributions of stress fibres and the unbundled actin meshwork to the anisotropy of cortical tension in response to cell shape | |
| LSD1抑制减弱了BRAFV600E结直肠癌中靶向治疗诱导的谱系可塑性 | Ladaika, C. | N/A | LSD1 inhibition attenuates targeted therapy-induced lineage plasticity in BRAFV600E colorectal cancer | |
| 内源性EWSR1-FLI1去泛素化位点等位基因能够调控肿瘤细胞系和异种移植模型中融合癌蛋白的表达 | McGinnis, J. H. | N/A | Endogenous EWSR1-FLI1 degron alleles enable control of fusion oncoprotein expression in tumor cell lines and xenografts | |
| DNA甲基化随机性与转录变异性相关，并识别出在基因定义的AML亚型中普遍存在的表观遗传干扰。 | Hilgart, E. | N/A | DNA methylation stochasticity is linked to transcriptional variability and identifies convergent epigenetic disruption across genetically-defined subtypes of AML | |
| 油菜素内酯和类黄酮醇能够提高花粉管萌发和生长的温度胁迫耐受性。 | Matsuura-Tokita, K. | N/A | Brassinosteroids and Flavonols Confer Temperature Stress Tolerance to Pollen Tube Germination and Growth | |
| 通过体外重组大麦Mla NLR基因鉴定效应物结合的关键功能获得性残基 | Zhang, X. | N/A | Identification of a key gain-of-function residue for effector binding by in vitro shuffling of barley Mla NLR genes | |
| 急性髓系白血病与慢性髓系白血病急变期中的共享遗传与调控机制 | Basu, S. | N/A | Shared Genetic and Regulatory Mechanisms in AcuteMyeloid Leukaemia and Blast Crisis Chronic MyeloidLeukaemia | |
| 晚成雏大脑与婴儿发声学习的演化 | Biazzi, R. B. | N/A | Altricial brains and the evolution of infant vocal learning | |
| 眶额皮层中的神经动力学揭示了认知策略 | Schiereck, S. S. | N/A | Neural dynamics in the orbitofrontal cortex reveal cognitive strategies | |
| BT-11 在阿尔茨海默病中的再利用潜力及其作用机制的见解 | Birnbaum, E. M. | N/A | BT-11 repurposing potential for Alzheimer's disease and insights into its mode of actions | |
| 神经退行性变会损害发育同步行为模式的巩固 | Laufer, L. | N/A | Neurodegeneration impairs the consolidation of developmentally synchronized behavioral patterns | |
| 先验的相关性如何？贝叶斯因果推断在易变环境中的动态感知 | Meijer, D. | N/A | How relevant is the prior? Bayesian causal inference for dynamic perception in volatile environments | |
| 动脉内脱氧核糖核酸酶治疗可改善老年小鼠的卒中预后 | Yin, J. | N/A | Intra-arterial Deoxyribonuclease therapy improves stroke outcomes in aged mice | |
| Ephrin介导的树突-树突排斥作用调节中枢神经系统中树突的区室特异性靶向定位 | Deng, X. | N/A | Ephrin-mediated dendrite-dendrite repulsion regulates compartment- specific targeting of dendrites in the central nervous system | |
| 用于可植入神经设备的软生物相容性聚合物光纤锥 | Meneghetti, M. | N/A | Soft biocompatible polymer optical fiber tapers for implantable neural devices | |
| 分泌型磷脂酶PLA2G12A通过脂解修饰胞外囊泡促进溶血磷脂信号传导，从而促进致病性Th17分化。 | Mochizuki, C. | N/A | Secreted phospholipase PLA2G12A-driven lysophospholipid signaling via lipolytic modification of extracellular vesicles facilitates pathogenic Th17 differentiation | |
| Sirtuin2阻断抑制了巨噬细胞和人源化小鼠中人类免疫缺陷病毒-1和结核分枝杆菌的复制 | Singh, V. K. | N/A | Sirtuin2 blockade inhibits replication of Human Immunodeficiency Virus-1 and 1 Mycobacterium tuberculosis in macrophages and humanized mice | |
| WAVE1和WAVE2在细胞进入过程中促进人乳头瘤病毒驱动的肌动蛋白聚合。 | Fernandez, D. J. | N/A | WAVE1 and WAVE2 facilitate human papillomavirus-driven actin polymerization during cellular entry | |
| Notch、β-连环蛋白和MAPK信号通路在双胚层动物Nematostella vectensis中分离了内胚层和中胚层。 | Haillot, E. | N/A | Notch, beta-catenin and MAPK signaling segregate endoderm and mesoderm in the diploblast Nematostella vectensis | |
| 海葵生命史中基质组分的分子动力学 | Bergheim, B. G. | N/A | Molecular dynamics of the matrisome across sea anemone life history | |
| 线粒体氧化还原开关授权动物形态发生的开始 | Kahlin, U. | N/A | A mitochondrial redox switch licenses the onset of morphogenesis in animals | |
| eIF4ET 调控减数分裂蛋白质组水平，以促进卵母细胞的形成和储存 | Bhatia, P. | N/A | eIF4ET regulates meiotic proteome levels to enable oocyte formation and storage | |
| 西澳大利亚城市灌木丛火灾后的兰花输家和赢家：与其他特征深度整合的响应连续体 | Brundrett, M. C. | N/A | Orchid losers and winners after fire in West Australian urban bushland: A response continuum deeply integrated with other traits | |
| 南极生物安全政策有效地管理了外来物种引入的比率。 | Leihy, R. I. | N/A | Antarctic biosecurity policy effectively manages the rates of alien introductions | |
| 跨物种分析揭示无普遍的程序性衰老机制：斑马鱼、果蝇和线虫单细胞转录组学的见解 | Niu, Y. | N/A | Cross-Species Analysis Reveals No Universal Programmed Aging Mechanism: Insights from Single-Cell Transcriptomics in Zebrafish, Fruit Fly, and Nematode | |
| 结合核基因组和线粒体基因组系统发育的生物信息学研究，以定义鞘翅目分类的关键节点 | Creedy, T. J. | N/A | Bioinformatics of combined nuclear and mitochondrial phylogenomics to define key nodes for the classification of Coleoptera | |
| 深入研究基因组以精确定位XX虹鳟自发性逆转的QTL位置 | Dehaullon, A. | N/A | In-depth investigation of genome to refine QTL positions for spontaneous sex-reversal in XX rainbow trout | |
| 染色体性别和性腺性别对小鼠社会动机的影响不同 | Chaturvedi, S. M. | N/A | Chromosomal and gonadal sex have differing effects on social motivation in mice | |
| Cloudgene 3：将Nextflow管道转化为强大的Web服务 | Forer, L. | N/A | Cloudgene 3: Transforming Nextflow Pipelines into Powerful Web Services | |
| scMultiNODE：多模态时间单细胞数据的整合模型 | Zhang, J. | N/A | scMultiNODE: Integrative Model for Multi-Modal Temporal Single-Cell Data | |
| GenePert：利用GenePT嵌入进行基因扰动预测 | Chen, Y. T. | N/A | GenePert: Leveraging GenePT Embeddings for Gene Perturbation Prediction | |
| 通过异质性测序识别细胞反应的调节因子 | Berg, K. | N/A | Identifying Modulators of Cellular Responses by Heterogeneity-sequencing | |
| 基于反应类型评分的化学酶合成规划 | Li, H. | N/A | Chemoenzymatic Synthesis Planning Guided by Reaction Type Score | |
| 新孢子虫（Neospora caninum）对宿主细胞膜生物物理动力学的调控：基于超光谱成像和相量分析的LAURDAN荧光研究 | Diaz, M. | N/A | Modulation of Host Cell Membrane Biophysics Dynamics by Neospora caninum: A Study Using LAURDAN Fluorescence with Hyperspectral Imaging and Phasor Analysis | |
| LassoESM：一种专为增强套索肽性质预测而定制的语言模型 | Mi, X. | N/A | LassoESM: A tailored language model for enhanced lasso peptide property prediction | |
| 从单分子荧光测量中获得的特定位置自由能表面参数，这些测量针对的是位于DNA复制叉接合处的激子耦合（iCy3）2二聚体探针 | Maurer, J. | N/A | Site-specific free energy surface parameters from single-molecule fluorescence measurements of exciton-coupled (iCy3)2 dimer probes positioned at DNA replication fork junctions | |
| 成纤维细胞激活蛋白定义了局部ccRCC中与上皮-间质转化相关的侵袭性癌细胞状态和预后 | Pellinen, T. | N/A | Fibroblast activation protein defines aggressive EMT-associated cancer cell state and prognosis in localized ccRCC | |
| 尤文氏肉瘤的起源：神经嵴向中胚层的胚胎重编程 | Vasileva, E. | N/A | Origin of Ewing sarcoma by embryonic reprogramming of neural crest to mesoderm | |
| 多亚基自噬捕获复合物促进胰腺癌中ER停滞的MHC-I降解。 | Berquez, M. | N/A | A multi-subunit autophagic capture complex facilitates degradation of ER stalled MHC-I in pancreatic cancer. | |
| 肥胖通过激活PPARD/PDK4/ANGPTL4通路诱导胃平滑肌细胞的表型转换。 | Dekkar, S. | N/A | Obesity induces phenotypic switching of gastric smooth muscle cells through the activation of the PPARD/PDK4/ANGPTL4 pathway | |
| 质体编码的RNA聚合酶构建了一个光诱导光合作用的物流链。 | Gillet, F.-X. | N/A | The plastid-encoded RNA polymerase structures a logistic chain for light-induced photosynthesis | |
| 对多种普通小麦种质资源中的籽粒进行多性状评价，包括高蛋白品种 | KOSINA, R. | N/A | Multi-character assessment of caryopsis in diverse common wheat germplasm,including high protein breeds | |
| 光通过解除psbA顺式ORF对翻译因子HCF173的抑制作用，激活植物中psbA的翻译。 | Williams-Carrier, R. | N/A | Light activates psbA translation in plants by relieving inhibition of translation factor HCF173 by the psbA ORF in cis | |
| 铝通过ABA诱导大麦根部的木栓质生物合成 | Meng, H. | N/A | Aluminium induces suberin biosynthesis in barley roots via ABA | |
| 不同年龄阶段大脑网络灵活性在运动学习中的不同作用 | Uehara, K. | N/A | Distinct roles of brain network flexibility in motor learning across age | |
| 躯体运动分离将睡眠时长与社会经济背景、屏幕使用时间、认知功能和精神病理学联系起来。 | Michael, C. | N/A | Somatomotor disconnection links sleep duration with socioeconomic context, screen time, cognition, and psychopathology | |
| 交易地点以换取空间：提高位置分辨率会降低海马编码中的情境容量 | Rooke, S. | N/A | Trading Place for Space: Increasing Location Resolution Reduces Contextual Capacity in Hippocampal Codes | |
| 一种怀旧脑音乐接口，用于增强年轻人和老年人群体的怀旧情感、幸福感及记忆鲜活度 | Sakakibara, Y. | N/A | A Nostalgia Brain-Music Interface for Enhancing Nostalgia, Well-Being, and Memory Vividness in Young and Elderly Individuals | |
| 发作相关啁啾声作为监测癫痫进展的生物标志物 | Bahador, N. | N/A | Ictal-Related Chirp as a Biomarker for Monitoring Seizure Progression | |
| 工作记忆中的任务无关特征会改变当前的视觉处理 | Shi, H. | N/A | Task-irrelevant features in working memory alter current visual processing | |
| 视觉引导运动过程中细胞类型特异性纹状体集合活动的动态失衡。 | Howe, M. | N/A | Dynamic imbalances in cell-type specific striatal ensemble activity during visually guided locomotion. | |
| 随着年龄的增长，沉思、担忧和积极思考等情绪大脑状态的独特性也会增加。 | Misaki, M. | N/A | Aging increases the distinctiveness of emotional brain states across rumination, worry, and positive thinking | |
| 哺乳期大鼠的幼崽防御行为：伏隔核壳区神经肽信号传导及其相互作用的机制 | Sanson, A. | N/A | Pup defence in lactating rats: The underlying neuropeptide signalling and their interactions in the nucleus accumbens shell | |
| 基准测试用于推断TCR特异性的无监督方法 | Jouannet, C. | N/A | Benchmarking unsupervised methods for inferring TCR specificity | |
| DDO佐剂流感病毒A型核蛋白mRNA疫苗诱导出强大的体液和细胞型1免疫反应，并保护小鼠免受挑战。 | Gnazzo, V. | N/A | DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge | |
| 新生儿重症监护室中母乳、捐赠母乳和母乳强化剂中的EGF和IgA | Tamar, C. | N/A | EGF and IgA in maternal milk, donor milk and milk fortifiers in the Neonatal Intensive Care Unit setting | |
| 含MT1-MMP的连接外泌体在乳腺癌进展中促进细胞外基质降解 | Palmulli, R. | N/A | Tethered exosomes containing MT1-MMP contribute to extracellular matrix degradation during breast cancer progression | |
| 在基因图增强的细胞状态流形上引导细胞转变 | Wang, T. | N/A | Directing cellular transitions on gene graph-enhanced cell state manifold | |
| 奥斯卡雷拉海绵属：隐藏的彩色多样性 | Guiollot, E. | N/A | The Oscarella sponges genus: a hidden yet colorful diversity | |
| 多变量性状演化：基于系统发育的定量遗传G矩阵演化模型。 | Blomberg, S. P. | N/A | Multivariate Trait Evolution: Models for the Evolution of the Quantitative Genetic G-Matrix on Phylogenies. | |
| 基因组洞察指导肺癌和膀胱肿瘤一线免疫治疗个性化反应 | Brea-Iglesias, J. | N/A | Genomic Insights Guiding Personalized First-Line Immunotherapy Response in Lung and Bladder Tumors | |
| 探索细鳞甲螨（Oppia nitens）的基因组：环境应激响应与毒性适应 | Adedokun, A. A. | N/A | Exploring The Genome of The Oribatid Mite, Oppia Nitens: Environmental Stress Response and Toxicity Adaptation | |
| 重温亚里士多德对蜜蜂的观察：蜜蜂普遍表现出高度的花期恒定性，但这种特性是由当地丰富的开花植物种类所塑造的。 | Shrotri, S. | N/A | Revisiting Aristotle's observation on bees: High floral constancy is common among bees but it is shaped by the locally abundant flowering species | |
| 动态肾脏类器官微生理分析平台 | Hong, S. | N/A | Dynamic Kidney Organoid Microphysiological Analysis Platform | |
| 利用大型语言模型实现异质生物医学样本元数据的自动化协调与大规模整合 | Higashi, K. | N/A | Automated Harmonization and Large-Scale Integration of Heterogeneous Biomedical Sample Metadata Using Large Language Models | |
| 通过融合基于spot的空间转录组学、位置和组织学信息，利用图卷积网络推断单细胞分辨率的空间基因表达 | Xue, S. | N/A | Inferring single-cell resolution spatial gene expression via fusing spot-based spatial transcriptomics, location and histology using GCN | |
| 利用系统发育和祖先序列重建方法，探索在猪与人之间传播的甲型流感病毒的遗传特征 | Anker, K. M. | N/A | Exploring genetic signatures of zoonotic influenza A virus at the swine-human interface with phylogenetic and ancestral sequence reconstruction | |
| 胰腺腺泡-导管化生过渡状态的DNA甲基化记忆在没有Kras突变的情况下改变Kras下游PI3K和Rho GTPase信号传导 | Feinberg, A. P. | N/A | DNA methylation memory of pancreatic acinar-ductal metaplasia transition state altering Kras-downstream PI3K and Rho GTPase signaling in the absence of Kras mutation | |
| 细胞内双调蛋白对于BRCA2突变/+乳腺上皮细胞在应对复制应激时维持异染色质稳定和基因组稳定性至关重要。 | Jiang, T. | N/A | Intracellular amphiregulin is critical for heterochromatin maintenance and genomic stability in response to replication stress in BRCA2mut/+mammary epithelial cells | |
| 几丁质酶-1抑制逆转了代谢失调，并在非酒精性脂肪性肝炎（MASH）动物模型中恢复了体内平衡。 | Drzewicka, K. | N/A | Chitinase-1 inhibition reverses metabolic dysregulation and restores homeostasis in MASH animal models | |
| 冰与气：年轻北美鹅掌楸叶片中冻融栓塞与冰冻扩散的可视化 | Johnson, K. M. | N/A | Ice and air: Visualisation of freeze-thaw embolism and freezing spread in young L. tulipifera leaves | |
| 差异基因表达分析鉴定出一组来自Solanum chacoense胚珠的防御素样肽，具有体外花粉管吸引活性。 | Liu, Y. | N/A | Differential gene expression analysis identifies a group of defensin like peptides from Solanum chacoense ovules with in vitro pollen tube attraction activity | |
| 选择性育种以确定性和光周期敏感性为目标的普通豆（Phaseolus vulgaris L.） | Denning-James, K. | N/A | Selective breeding for determinacy and photoperiod sensitivity in common bean (Phaseolus vulgaris L.) | |
| E2F4DN对p38MAPK磷酸化的抵抗通过Cited2减轻了DNA损伤诱导的神经元死亡 | Llabres-Mas, A. M. | N/A | Resistance of E2F4DN to p38MAPK phosphorylation attenuates DNA damage-induced neuronal death via Cited2 | |
| 双光子成像中血流动力学阻塞效应的定量分析 | Yogesh, B. | N/A | Quantification of the effect of hemodynamic occlusion in two-photon imaging | |
| 一种基于功能性磁共振成像（fMRI）的方法，用于测量视觉皮层中视觉场各部分的对比度敏感度 | Chow-Wing-Bom, H. T. | N/A | An fMRI-based Approach for Measuring Contrast Sensitivity Across the Visual Field in Visual Cortex | |
| 使用多线性探针在小鼠中进行经颅脑全域功能超声和超声定位显微镜 | Vert, M. | N/A | Transcranial Brain-Wide Functional Ultrasound and Ultrasound Localization Microscopy in Mice using Multilinear Probes | |
| Slit调控果蝇大脑中树突和轴突的区室特异性靶向 | Deng, X. | N/A | Slit regulates compartment-specific targeting of dendrites and axons in the Drosophila brain | |
| 记忆系统的适应不良损害了背侧CA1依赖的时间绑定和陈述性记忆——以自闭症Cntnap2敲除小鼠模型为例 | Rawlinson, E. C. | N/A | Maladaptation of Memory Systems Impairs Dorsal CA1-Dependent Temporal Binding and Declarative Memory in The Cntnap2 Knockout Mouse Model of Autism | |
| 揭示头颈部癌症患者对SARS-CoV-2的体液和细胞免疫反应：罗马尼亚疫苗接种与自然感染的比较研究 | Marutescu, L. | N/A | Unveiling Humoral and Cellular Immune Responses to SARS-CoV-2 in Head and Neck Cancer: A Comparative Study of Vaccination and Natural Infection in Romania | |
| 假单胞菌利用混合碳源生产异戊二烯醇的替代途径导致乙酸耐受性的变化 | de Siqueira, G. M. V. | N/A | Alternate routes to acetate tolerance lead to varied isoprenol production from mixed carbon sources in Pseudomonas putida | |
| 克服艰难梭菌分型中的重复性和变异性挑战 | Bravo-Anton, L. | N/A | Overcoming Challenges of Reproducibility and Variability for the Clostridioides difficile typification | |
| 针对肿瘤相关微生物具核梭杆菌（F. nucleatum）的靶向治疗：利用生物工程益生菌表达引导性抗菌肽（gAMP） | Choudhury, A. | N/A | Targeted therapy of oncomicrobe F. nucleatum with bioengineered probiotic expressing guided antimicrobial peptide (gAMP) | |
| NINJ1是HSV-1在小鼠巨噬细胞中的限制因子 | Broz, P. | N/A | NINJ1 is a restriction factor for HSV-1 in mouse macrophages | |
| 温带噬菌体提高抗生素在秀丽隐杆线虫感染模型中的有效性 | Fatima, R. | N/A | Temperate phages increase antibiotic effectiveness in a Caenorhabditis elegans infection model | |
| 肝素在宿主抵抗播散性念珠菌病中的关键作用 | Arekar, T. | N/A | Essential role of Hepcidin in host resistance to disseminated candidiasis | |
| Tad菌毛排列复合体的结构揭示了菌毛延伸的周质通道 | Evans, S. L. | N/A | The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension | |
| 替米沙坦主要通过AT1/PPARγ轴抑制JEV感染。 | Datey, A. | N/A | Telmisartan impedes JEV infection predominately via AT1/PPARγ axis | |
| 对反义抗生素耐药决定因素的系统鉴定表明，适应策略依赖于递送肽 | Mulkern, A. J. | N/A | A systematic identification of resistance determinants to antisense antibiotics suggests adaptation strategies dependent on the delivery peptide | |
| 鉴定出一组基于吡咯并嘧啶的SARS-CoV-2 Mac1抑制剂，能够抑制冠状病毒的复制 | Pfannenstiel, J. J. | N/A | Identification of a series of pyrrolo-pyrimidine based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication | |
| 机械化学图案化定位了管腔上皮组织者的位置 | Weevers, S. L. | N/A | Mechanochemical Patterning Localizes the Organizer of a Luminal Epithelium | |
| 描述外来物种对西南不列颠哥伦比亚地区单体三刺鱼（Gasterosteus aculeatus）种群形态的影响 | Kienzle, H. M. | N/A | Characterizing the impacts of exotic species on the morphology of solitary threespine stickleback (Gasterosteus aculeatus) populations in southwestern British Columbia | |
| 利用真核细胞重编程的tracrRNAs在人类细胞中劫持并记录细胞内RNAs | Lee, S.-H. | N/A | Hijacking and recording intracellular RNAs in human cells using eukaryotic reprogrammed tracrRNAs | |
| 多铜氧化酶漆酶的定向进化用于细胞表面邻近标记和电子显微镜技术 | Lee, S.-Y. | N/A | Directed evolution of the multicopper oxidase laccase for cell surface proximity labeling and electron microscopy | |
| 基于模式的基因组挖掘指导从海洋链霉菌中发现抗菌药物吲哚吡咯A。 | Sweeney, D. | N/A | Pattern-based genome mining guides discovery of the antibiotic indanopyrrole A from a marine streptomycete. | |
| 碳纳米点作为红色荧光探针用于紫杉醇治疗期间DNA动力学的超分辨率显微成像 | Garg, R. | N/A | Carbon nanodots as a red emissive fluorescent probe for the super-resolution microscopy of DNA dynamics during paclitaxel treatment | |
| 结核分枝杆菌mce1操纵子中长链脂肪酸辅酶A合成酶FadD5的结构酶学研究 | Rahman, M. A. | N/A | Structural enzymological studies of the long chain fatty acyl-CoA synthetase FadD5 from the mce1 operon of Mycobacterium tuberculosis | |
| VAPOR：使用传输算子的变分自编码器解耦发育中的共发生生物过程 | Sheng, J. | N/A | VAPOR: Variational autoencoder with transport operators decouples co-occurring biological processes in development | |
| DNMT3AR882H在原发性人类急性髓系白血病中并非疾病维持所必需，但与白血病干细胞频率增加相关 | Koehnke, T. | N/A | DNMT3AR882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency | |
| 核糖体生物发生超激活与ErbB信号传导介导的网络重塑导致对FGFR2抑制的适应性抗性 | Zhang, T. | N/A | Ribosomal Biogenesis Hyperactivation and ErbB signalling Mediated Network Rewiring Causes Adaptive Resistance to FGFR2 Inhibition | |
| 主基因型塑造了硬粒小麦的根系真菌群落 | TRINQUIER, M. | N/A | Host genotype shapes root mycobiota in durum wheat | |
| 基于表面的深度学习皮质形状分析方法 | Im, Y. | N/A | A Surface-based deep learning approach for cortical shape analysis | |
| 在并行操作和监控环境时，自适应的目光与手部协调 | Fooken, J. | N/A | Adaptive Gaze and Hand Coordination while Manipulating and Monitoring the Environment in Parallel | |
| 兴奋性毒性诱导的神经营养素受体TrkB-FL的逆向运输调节高尔基体稳定性，并成为中风神经保护的靶点 | Esteban-Ortega, G. M. | N/A | Retrograde transport of neurotrophin receptor TrkB-FL induced by excitotoxicity regulates Golgi stability and is a target for stroke neuroprotection | |
| Ninjurin-1介导的质膜破裂是一个两步过程，需要细胞膨胀。 | Hartenian, E. | N/A | Ninjurin-1 mediated plasma membrane rupture is a two-step process requiring cell swelling | |
| 白色念珠菌多药耐药ABC转运蛋白CDR1的结构、动力学和进化 | Shin, J. | N/A | Structure, dynamics and evolution of the Candida albicans multi-drug resistance ABC transporter CDR1 | |
| 植物化学特性及印楝素对选定人类细菌病原体的抗菌特性 | Ibuot, A. A. | N/A | Phytochemical characterization and antimicrobial properties of Azadirachtin indica against selected bacterial human pathogens | |
| 年龄、性别和线粒体单倍型影响遗传多样性大鼠模型中的肠道微生物组组成和代谢物。 | Nguyen, H. V. M. | N/A | Age, Sex, and mitochondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat model. | |
| 抗生素的杀伤力决定了分枝杆菌感染的结果 | Jovanovic, A. | N/A | Antibiotic lethality dictates mycobacterial infection outcomes | |
| 鉴定出一大批具有广泛宿主范围的Enterobacter巨型噬菌体，这些噬菌体可感染致病性γ-变形菌 | Kanhirun, N. | N/A | Identification of a large cohort of Enterobacter jumbo phages with broad host ranges across pathogenic Gammaproteobacteria | |
| 德克萨斯州分离的牛源性流感A(H5N1)病毒的复制动力学、致病性及病毒诱导的细胞反应 | Mostafa, A. | N/A | Replication Kinetics, Pathogenicity and Virus-induced Cellular Responses of Cattle-origin Influenza A(H5N1) Isolates from Texas, United States | |
| 工程化多价抗体片段的结构景观及其作为结晶支架的应用 | Kedari, A. | N/A | Structural landscape of engineered multivalent antibody fragments and their application as crystallization scaffolds | |
| 靶向二斑叶螨Tetranychus urticae前体rRNA的反义DNA杀螨剂作为增强真菌绿僵菌Metarhizium robertsii功效的试剂 | Gavrilova, D. | N/A | Antisense DNA acaricide targeting pre-rRNA of two-spotted spider mite Tetranychus urticae as efficacy-enhancing agent of fungus Metarhizium robertsii | |
| 植物线粒体核糖体成熟与翻译的结构研究 | Skaltsogiannis, V. | N/A | Structural insights into maturation and translationof a plant mitoribosome | |
| TreeFormer：一种基于Transformer的树重排操作，用于系统发育重建 | Ly-Trong, N. | N/A | TreeFormer: A transformer-based tree rearrangement operation for phylogenetic reconstruction | |
| TaxonGPT：利用生成式人工智能进行分类学分类 | Huang, H. | N/A | TaxonGPT: Taxonomic Classification Using Generative Artificial Intelligence | |
| 利用斯坦波霉素聚酮合酶中酰基转移酶的固有杂泛性进行类似物的突变合成 | Su, L. | N/A | Exploiting the inherent promiscuity of the acyl transferase of the stambomycin polyketide synthase for the mutasynthesis of analogues | |
| SCAD递送平台：一种高效的中枢神经系统和肝外寡核苷酸治疗的新方法 | Kang, M. | N/A | SCAD Delivery Platform: A Novel Approach for Efficient CNS and Extrahepatic Oligonucleotide Therapeutics | |
| 突变株和非突变株枯草芽孢杆菌对利用西瓜籽生产奥吉里（ogiri）的微生物多样性及理化性质的影响 | Babatuyi, C. | N/A | Effects of mutant and non-mutant strains of Bacillus subtilis to produce ogiri from Citrullus vulgaris seeds on their microbial diversity and physicochemical properties | |
| 一种紧密调控酵母RNA稳态的共转录机制 | Esteban-Serna, S. | N/A | A co-transcriptional mechanism for tightly controlling RNA homeostasis in yeast | |
| 从数千个随机内含子中学习的内含子介导增强的序列决定因素 | Kowal, E. J. | N/A | Sequence determinants of intron-mediated enhancement learned from thousands of random introns | |
| 研究泼尼松龙对杜氏肌营养不良小鼠模型行为的影响 | Verhaeg, M. | N/A | Investigating the effects of prednisolone on behavior in mouse models of Duchenne muscular dystrophy | |
| 共享转录组特征揭示了突触修剪作为阿尔茨海默病与癫痫之间的联系 | Li, H. | N/A | Shared Transcriptomic Signatures Reveal Synaptic Pruning as a Link Between Alzheimer's Disease and Epilepsy | |
| 皮质-伏隔核通路的转录组分析揭示了应激易感性背后的性别特异性改变 | Pessoni, A. M. | N/A | Transcriptional profiling of the cortico-accumbal pathway reveals sex-specific alterations underlying stress susceptibility | |
| 通过表达谱分析和结构分析揭示重复基因的功能命运 | Warwick Vesztrocy, A. | N/A | Unveiling the Functional Fate of Duplicated Genes Through Expression Profiling and Structural Analysis | |
| 通过适当建模遗传、环境和社会文化因素，提高在代表性不足群体中的全基因组关联研究（GWAS）表现 | Cataldo-Ramirez, C. | N/A | Improving GWAS performance in underrepresented groups by appropriate modeling of genetics, environment, and sociocultural factors | |
| 学习推断传递性：前运动皮层中对心理直线上序列排序的推断 | Raglio, S. | N/A | Learning to infer transitively: serial ordering on a mental line in premotor cortex | |
| # BioRxiv 2024-10-28 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 影响单基因树年代测定准确性和精确性的因素 | Louvel, G. | N/A | Factors influencing the accuracy and precision in dating single gene trees | |
| 性染色体基因表达与雌性斑胸草雀在激素调控后的鸣叫学习相关 | Davenport, M. | N/A | Sex chromosome gene expression associated with vocal learning following hormonal manipulation in female zebra finches | |
| 系统发育状态依赖性多样化模型（SSEs）的隐藏模型空间：一致性、挑战与机遇 | Tarasov, S. | N/A | The Hidden Model Space of Phylogenetic State-Dependent Diversification Models (SSEs): Congruence, Challenges, and Opportunities | |
| 脑细胞外基质中的不可移动阴离子成分取代了细胞外氯离子 | Normoyle, K. P. | N/A | Displacement of extracellular chloride by immobile anionic constituents of the brain's extracellular matrix | |
| BiATNovo：一种基于注意力机制的双向从头测序框架，用于数据非依赖性采集质谱分析 | Yang, S. | N/A | BiATNovo: An Attention-based Bidirectional De Novo Sequencing Framework for Data-Independent-Acquisition Mass Spectrometry | |
| 从贝叶斯到达尔文：基于采样的贝叶斯推断作为进化搜索的一种前适应 | Csillag, M. | N/A | From Bayes to Darwin: evolutionary search as an exaptation from sampling-based Bayesian inference | |
| 听觉皮层解剖结构反映了多语言的语音经验。 | Kepinska, O. | N/A | Auditory cortex anatomy reflects multilingual phonological experience | |
| I-SVVS：整合随机变分变量选择方法，用于探索多组学微生物组数据的联合模式 | Dang, T. | N/A | I-SVVS: Integrative stochastic variational variable selection to explore joint patterns of multi-omics microbiome data | |
| HSF-DREB-MYB转录调控模块调控香蕉（Musa acuminata）中黄酮醇生物合成及黄酮类B环羟基化 | Naik, J. | N/A | The HSF-DREB-MYB transcriptional regulatory module regulates flavonol biosynthesis and flavonoid B-ring hydroxylation in banana(Musa acuminata) | |
| Extramacrochaetae 通过非凋亡性胱天蛋白酶活性调节果蝇眼中的 Notch 信号传导 | Baker, N. E. | N/A | Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity | |
| 可视化液-液相变 | Sahoo, B. R. | N/A | Visualizing liquid-liquid phase transitions | |
| 过度表达人类RAMP1的小鼠对治疗运动敏感性的偏头痛疗法具有抵抗力。 | Rahman, S. M. | N/A | Human RAMP1 overexpressing mice are resistant to migraine therapies for motion sensitivity | |
| 片段扩增的转录组和蛋白质组学影响 | Fritts, R. K. | N/A | The transcriptomic and proteomic ramifications of segmental amplification | |
| 各方面都极端：由于种群数量持续偏小，雪豹的遗传多样性极低 | Solari, K. A. | N/A | Extreme in Every Way: Exceedingly Low Genetic Diversity in Snow Leopards Due to Persistently Small Population Size | |
| 一氧化氮调节小鼠视网膜神经节细胞中的一部分对比度抑制作用 | Gonschorek, D. | N/A | Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells | |
| 胚胎来源的脑内常驻巨噬细胞维持睡眠-觉醒回路 | Seifinejad, A. | N/A | Embryo-derived brain-resident macrophages sustain sleep-wake circuits | |
| 地理分布广泛且新型的嗜血支原体和巴尔通体在墨西哥无尾蝙蝠及其同域分布的北美蝙蝠物种中的发现 | Becker, D. | N/A | Geographically widespread and novel hemotropic mycoplasmas and bartonellae in Mexican free-tailed bats and sympatric North American bat species | |
| 基于多种减毒机制的减毒活SARS-CoV-2疫苗候选株的免疫原性和安全性 | Suzuki, M. | N/A | Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms | |
| 抑制NFAT会促进人体组织驻留型子宫自然杀伤细胞的丧失，并伴随妊娠并发症的发生。 | Asiimwe, R. | N/A | Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans | |
| Smad4和TGF-β1依赖的基因表达生物标志物在条件性肠道腺瘤、类器官和结直肠癌中的研究。 | Surakhy, M. | N/A | Smad4 and TGF-β1 dependent gene expression biomarkers in conditional intestinal adenoma, organoids and colorectal cancer. | |
| 脂氧素B4和眼压对视神经中疾病相关小胶质细胞的调控 | Maurya, S. | N/A | Regulation of Diseases-Associated Microglia in the Optic Nerve by Lipoxin B4 and Ocular Hypertension | |
| 人类气道巨噬细胞在IFN-γ的作用下发生代谢重编程，导致依赖糖酵解的功能可塑性。 | Cox, D. J. | N/A | Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity. | |
| Sir2和Fun30通过Mcm解旋酶定位和核小体占据来调节核糖体DNA复制时序 | Lichauco, C. | N/A | Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy | |
| Tcf21作为创始转录因子在指定Foxd1细胞为近球小管细胞谱系中的作用 | Anjum, H. | N/A | Tcf21 as a Founder Transcription Factor in Specifying Foxd1 Cells to the Juxtaglomerular Cell Lineage | |
| 启用微观真实大脑的电场模型 | Qi, Z. | N/A | Enabling Electric Field Model of Microscopically Realistic Brain | |
| 快速且灵敏的蛋白质复合物比对工具：Foldseek-Multimer | Kim, W. | N/A | Rapid and Sensitive Protein Complex Alignment with Foldseek-Multimer | |
| Panx1敲除通过改变AMPK/mTOR信号通路和突触组成加剧了斑马鱼中的氧化应激和细胞死亡 | Zoidl, G. S. O. | N/A | Panx1 Ablation Aggravates Oxidative Stress and Cell Death by Altering AMPK/mTOR signaling Pathways and the Composition of Synapses in the Zebrafish | |
| 开放通道液滴微流控平台用于被动生成人类精子微滴 | Nicholson, T. M. | N/A | Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets | |
| 揭示从序列中得出的蛋白质结构域中的保守别构热点 | Hacisuleyman, A. | N/A | Unveiling Conserved Allosteric Hot Spots in Protein Domains from Sequences | |
| 古代基因组揭示了公元9至10世纪在喀尔巴阡盆地发生的阿瓦尔-匈牙利转变 | Gerber, D. | N/A | Ancient genomes reveal Avar-Hungarian transformations in the 9-10th centuries CE in the Carpathian Basin | |
| 生活在金属污染河流中的褐鳟的基因组特征及对金属耐受性的转录反应 | Paris, J. R. | N/A | The genomic signature and transcriptional response of metal tolerance in brown trout inhabiting metal-polluted rivers | |
| 建模进化谱系的速率并预测扩散模式 | Bastide, P. | N/A | Modeling the velocity of evolving lineages and predicting dispersal patterns | |
| 内侧纹状体核中GABA/谷氨酸共传递神经元对选择方向和结果的混合表征 | Locantore, J. | N/A | Mixed representations of choice direction and outcome by GABA/glutamate cotransmitting neurons in the entopeduncular nucleus | |
| 综合网络分析揭示阿尔茨海默病中Aβ-Tau相互作用的新型调节因子 | Kitani, A. | N/A | Integrative Network Analysis Reveals Novel Moderators of Aβ-Tau Interaction in Alzheimer's Disease | |
| 细胞单层中的信息传递：一项数值研究 | Nałecz-Jawecki, P. | N/A | Information transmission in a cell monolayer: A numerical study | |
| 在发育过程中处于复杂声学环境中的斑胸草雀，其听觉感知和编码效率得到了增强。 | Moseley, S. M. | N/A | A complex acoustical environment during development enhances auditory perception and coding efficiency in the zebra finch | |
| 前馈网络中信号汇聚和发散的尖峰编码的时间分辨率 | Mobille, Z. | N/A | Temporal resolution of spike coding in feedforward networks with signal convergence and divergence | |
| 提高中欧和东欧家庭花园的生物多样性需要区域性的策略 | Varga-Szilay, Z. | N/A | Improving biodiversity in Central and Eastern European domestic gardens needs regionally scaled strategies | |
| Biom3d，一个模块化的框架，用于托管和开发3D分割方法 | Mougeot, G. | N/A | Biom3d, a modular framework to host and develop 3D segmentation methods | |
| 鉴定B群链球菌中的乙二醛酶A及其对甲基乙二醛耐受性和毒力的贡献 | Akbari, M. S. | N/A | Identification of Glyoxalase A in Group B Streptococcus and its contribution to methylglyoxal tolerance and virulence | |
| 肥胖中铁死亡的调控：饮食限制和运动的肌肉类型特异性效应 | Ji, F. | N/A | Regulation of Ferroptosis in Obesity: Muscle Type-Specific Effects of Dietary Restriction and Exercise | |
| 虚弱综合征对骨骼肌组织学的影响：运动的预防作用 | Ji, F. | N/A | The Impact of Frailty Syndrome on Skeletal Muscle Histology: Preventive Effects of Exercise | |
| ADAM通过与大型蛋白质复合物相互作用，调控组蛋白修饰、基因表达和剪接过程。 | Pandey, A. | N/A | ADAM interact with large protein complexes to regulate Histone modification, gene expression and splicing. | |
| 棉花纤维细胞壁性质的发育变异性与重要的农艺性状相关联 | Wilson, M. C. | N/A | Developmental variability in cotton fiber cell wall properties linked to important agronomic traits | |
| 通过BONCAT和基于点击化学的新合成蛋白质富集技术追踪微生物群落中的活跃成员 | Hellwig, P. | N/A | Tracing active members in microbial communities by BONCAT and click chemistry-based enrichment of newly synthesised proteins | |
| 基于秀丽隐杆线虫毒性测试的自动化微流控平台 | Wu, J. | N/A | An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans | |
| 乙醇培养物中Cyberlindnera jadinii的生理定量与生物量组成 | Vieira-Lara, M. A. | N/A | Quantitative physiology and biomass composition of Cyberlindnera jadinii in ethanol-grown cultures | |
| 通过整合机制建模和深度学习发现可解释的模式规则 | Lu, J. | N/A | Discovery of interpretable patterning rules by integrating mechanistic modeling and deep learning | |
| 特定纹状体神经元群的异常过度活跃通过高分辨率聚类揭示了编码不同运动障碍行为的机制。 | Alcacer, C. | N/A | Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering | |
| 作物育种中基因组预测集成方法预测性能的改进 | Tomura, S. | N/A | Improvements in Prediction Performance of Ensemble Approaches for Genomic Prediction in Crop Breeding | |
| 通过蛋白质组学检测ESKAPE病原体的抗生素抗性并同时鉴定其物种 | Blumenscheit, C. | N/A | Antibiotic resistance detection and concomitant species identification of ESKAPE pathogens by proteomics | |
| 在小鼠齿状回中，5-HT7受体的激活并不影响穿通路径突触处的θ脉冲诱导的可塑性。 | Siwiec, M. | N/A | Activation of 5-HT7 receptors in the mouse dentate gyrus does not affect theta-burst-induced plasticity at the perforant path synapse | |
| 基于深度学习的基因扰动效应预测尚未超越简单的线性方法。 | Ahlmann-Eltze, C. | N/A | Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods | |
| CAR Treg与抗CD154协同作用介导感染性耐受，以决定心脏移植结果。 | Durgam, S. S. | N/A | CAR Treg synergy with anti-CD154 mediates infectious tolerance to dictate heart transplant outcomes. | |
| 催产素受体调控草原田鼠配对结合和发育的不同方面 | Sharma, R. | N/A | Oxytocin receptor controls distinct components of pair bonding and development in prairie voles | |
| 编码于自我扩增RNA中的广谱免疫抑制能够实现持续、可逆且非免疫刺激性的表达。 | Lim, T. K. Y. | N/A | Broad-spectrum immune suppression encoded in self-amplifying RNA enables sustained, reversible, and non-immunostimulatory expression | |
| 区间删失对生物高通量筛选中数据准确性和机器学习性能的影响 | Doffini, V. | N/A | Impact of Interval Censoring on Data Accuracy and Machine Learning Performance in Biological High-Throughput Screening | |
| 甲基组揭示了两种植物物种种群中最近的进化变化 | Korfmann, K. | N/A | Methylomes reveal recent evolutionary changes in populations of two plant species | |
| 单细胞核测序揭示肾上腺皮质癌中的复制压力 | Popova, L. V. | N/A | Single Nuclei Sequencing Reveals Replication Stress in Adrenocortical Carcinoma | |
| 高血压中的肠道微生物代谢通量紊乱 | Wenkai, L. | N/A | Gut microbial metabolic flux disorder in hypertension | |
| 甲虫-真菌互利共生体系中共生真菌的基因组多样化 | Huang, Y.-T. | N/A | Genome diversification of symbiotic fungi in beetle-fungus mutualistic symbiosis | |
| CXCL10/CXCR3信号传导引发神经衰老及认知障碍 | Patel, M. | N/A | CXCL10/CXCR3 Signaling Induces Neural Senescence and Cognitive Impairments | |
| 艺术的隐秘拓扑：一扇通往人类感知的大门 | Dmitruk, E. | N/A | Art's Hidden Topology: A window into human perception | |
| 人类谱系的深度合并历史 | Cousins, T. | N/A | Deep coalescent history of the hominin lineage | |
| 年龄相关的大脑成熟与年轻化：丰富环境中神经3D染色质互作组的演变 | Gancedo-Verdejo, J. | N/A | Age-Dependent Maturation and Rejuvenation of the Neural 3D Chromatin Interactome in Enriched Environments | |
| 在早更新世至中更新世过渡期间，人类经历了严重瓶颈的证据不足。 | Cousins, T. | N/A | Insufficient evidence for a severe bottleneck in humans during the Early to Middle Pleistocene transition | |
| 四刺鱼（Apeltes quadracus）具有XY性染色体系统，其X和Y染色体上均存在多态性倒位。 | Liu, Z. | N/A | The fourspine stickleback (Apeltes quadracus) has an XY sex chromosome system with polymorphic inversions on both X and Y chromosomes | |
| 一种I型3' UTR衍生的sRNA参与了金黄色葡萄球菌中的血红素代谢和毒力 | Silard, C. | N/A | A type I 3' UTR-derived sRNA is involved in heme metabolism and virulence in Staphylococcus aureus | |
| 可分离的默认模式网络连接模式在精神病风险中导致不同的症状 | Ajunwa, C. C. | N/A | Dissociable Default Mode Network Connectivity Patterns Underlie Distinct Symptoms in Psychosis Risk | |
| 身体游走揭示了思维的具身维度，具有独特的影响和神经特征。 | Banellis, L. | N/A | Body-wandering reveals an embodied dimension of thought with distinct affective and neural signatures | |
| 斑马鱼中个体保守神经元微外显子和其主调控因子的表型影响 | Lopez-Blanch, L. | N/A | Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish | |
| 具有多种中间神经元类型的皮层网络在预测编码过程中产生振荡模式 | Lee, K. | N/A | Cortical networks with multiple interneuron types generate oscillatory patterns during predictive coding | |
| 运动补偿而非感觉误差调节自然言语生成中的序列依赖性 | Lu, Y. | N/A | Motor compensations, not sensory errors, regulate serial dependence in naturalistic speech production | |
| 小鼠少突胶质前体细胞在整个生命周期中的转录组特征 | Heo, D. | N/A | Transcriptional profiles of murine oligodendrocyte precursor cells across the lifespan | |
| 优势逆转保护了在时间变化环境中具有较大效应的抗性多态性 | Karageorgi, M. | N/A | Dominance reversal protects large-effect resistance polymorphisms in temporally varying environments | |
| 蚂蚁导航行为的比较研究 | Shen, X. | N/A | A comparative study of navigation behaviours in ants | |
| 昆虫生物群图集数据：瑞典和马达加斯加陆生节肢动物的元条形码调查 | Miraldo, A. | N/A | Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar | |
| 解析南美洲沿海洛马斯植物多样性的逆纬度梯度：环境和地理因素的影响 | Gonzales, F. N. | N/A | Unraveling the inverse latitudinal gradient: Environmental and geographic influences on plant diversity in South American coastal lomas | |
| 气候、天气和地理因素共同塑造了北美西部种子质量的变化和下降趋势。 | Lenzo, L. | N/A | Climate, weather, and geography shape seed mass variation and decline across western North America | |
| 发展新技术以保护生态系统：采用适应性管理进行规划 | Pascal, L. V. | N/A | Developing new technologies to protect ecosystems: planning with adaptive management | |
| 改进入侵蓝蟹（Callinectes sapidus）的监测：结合环境DNA和公民观察 | Delrieu-Trottin, E. | N/A | Improving the monitoring of the invasive Blue Crab (Callinectes sapidus): combining environmental DNA and citizen observations | |
| 腺嘌呤DNA甲基化与转录相关，在真核生物中广泛存在。 | Romero Charria, P. | N/A | Adenine DNA methylation associated to transcription is widespread across eukaryotes | |
| 通过花粉间接从头再生实现药用型大麻（Cannabis sativa L.）的双单倍体发育。 | Tonolo, F. | N/A | Double haploid development in drug-type Cannabis sativa L. through microspore indirect de-novo plant regeneration. | |
| 基于受体的蛋白质结合在天鹅绒虫粘液的超分子网络中 | Hu, Z. | N/A | Receptor-based protein binding in the supramolecular network of velvet worm slime | |
| Muscle-3D：可扩展的多重蛋白质结构比对 | Edgar, R. C. | N/A | Muscle-3D: scalable multiple protein structure alignment | |
| 经典的统计方法在识别乳腺癌患者生存的新靶点方面具有强大的作用。 | Insawang, B. | N/A | Classical statistical methods are powerful for the identification of novel targets for the survival of breast cancer patients | |
| 解决脊椎动物古生物学中的“个体发育问题” | Napoli, J. | N/A | Resolving the "Ontogeny Problem" in Vertebrate Paleontology | |
| 眼见不为实？改善科学博士生导师关系的视角获取干预的混合效应 | Tuma, T. T. | N/A | Seeing isn't believing? Mixed effects of a perspective-getting intervention to improve mentoring relationships for science doctoral students | |
| Nematostella Wnt/β-catenin破坏复合体为理解主要后生动物信号转导途径调控的进化提供了见解。 | Sun, H. | N/A | The Nematostella Wnt/β-catenin destruction complex provides insight into the evolution of the regulation of a major metazoan signal transduction pathway | |
| 在喀斯特天窗中的长期杂交揭示了洞穴鱼类眼睛丧失的遗传基础 | Kellermeyer, R. | N/A | Long-term hybridization in a karst window reveals the genetic basis of eye loss in cavefish | |
| 五个甜瓜（Cucumis melo L.）品种Ananas、Canton、PI 414723、Vedrantais和Zhimali的核与细胞器基因组组装，这些品种属于不同的植物分类群。 | Belinchon-Moreno, J. | N/A | Nuclear and organelle genome assemblies of five Cucumis melo L. accessions, Ananas, Canton, PI 414723, Vedrantais and Zhimali, belonging to diverse botanical groups | |
| 前列腺癌中的miRNA生物标志物：利用机器学习提高诊断准确性 | Singh, S. | N/A | miRNA Biomarkers in Prostate Cancer: Leveraging Machine Learning for Improved Diagnostic Accuracy | |
| 自动催化组装的一种嵌合氨基酸-RNA合成酶核酶 | Radakovic, A. | N/A | Autocatalytic assembly of a chimeric aminoacyl-RNA synthetase ribozyme | |
| 开发自主神经系统多尺度神经连接知识库 | Imam, F. T. | N/A | Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System | |
| APOBEC3A通过改变上皮间质转化驱动卵巢癌的转移 | Devenport, J. M. | N/A | APOBEC3A drives metastasis of ovarian cancer by altering epithelial-to-mesenchymal transition | |
| 通过比较基因组学和西部合鸣蛙的新染色体水平基因组，揭示了两栖类的宏观共线性、“叛逆”基因和新性连锁区域 | Chen, Y. | N/A | Insights on macrosynteny, 'rebel' genes, and a new sex-linked region in anurans from comparative genomics and a new chromosome-level genome for the western chorus frog | |
| 阿尔茨海默病人类大脑中长非编码RNA的空间表达 | Ng, B. | N/A | Spatial Expression of Long Non-Coding RNAs in Human Brains of Alzheimer's Disease | |
| 数字降噪处理对皮层下言语编码的影响及其与行为结果的关系 | Kim, S. | N/A | Effect of digital noise-reduction processing on subcortical speech encoding and relationship to behavioral outcomes | |
| 时间上下文对多时间尺度视觉的影响 | Lee, K. | N/A | The influence of temporal context on vision over multiple time scales | |
| 阿尔茨海默病患者的脑提取物在血管化神经免疫类器官中诱导多种病理，用于疾病建模和药物发现 | Ji, Y. | N/A | Alzheimer's Disease Patient Brain Extracts Induce Multiple Pathologies in Vascularized Neuroimmune Organoids for Disease Modeling and Drug Discovery | |
| 左乙拉西坦通过SV2a依赖性调节阿尔茨海默病模型中App加工过程，从而抑制Aβ42的产生。 | Rao, N. R. | N/A | Levetiracetam prevents Aβ42 production through SV2a-dependent modulation of App processing in Alzheimer's disease models | |
| 体育活动在缓解与年龄相关的步态神经肌肉控制变化中的作用 | Nunez-Lisboa, M. A. | N/A | The Role of Physical Activity in Mitigating Age-Related Changes in the Neuromuscular Control of Gait | |
| NAD+及EVA1-C依赖的神经功能缺陷逆转，是通过在tau病动物模型中差异性选择性RNA剪接介导的。 | Ai, R. | N/A | NAD+ - and EVA1-C-dependent reversal of neurological deficits is mediated by differential alternative RNA splicing in tauopathic animal models | |
| 跨眼跳空间更新和错位定位的电路模型 | Wang, X. | N/A | A circuit model for transsaccadic space updating and mislocalization | |
| 听觉皮层中的正交频谱和时间包络表示 | Takahashi, K. | N/A | Orthogonal spectral and temporal envelope representation in auditory cortex | |
| 急性有氧运动增强活跃个体的联想学习能力，但对久坐个体无此效果。 | Gultig, K. D. | N/A | Acute Aerobic Exercise Enhances Associative Learning in Active but not Sedentary Individuals | |
| 多模态成像结合单突触分析中的突触组成、活性、mRNA翻译及动态变化 | Falkovich, R. | N/A | Synaptic composition, activity, mRNA translation and dynamics in combined single-synapse profiling using multimodal imaging | |
| 化学感觉对斑马鱼幼体眼部与身体协调的调控 | Sy, S. K. H. | N/A | Chemosensory modulation of eye-body coordination in larval zebrafish | |
| 恢复与多发性硬化症相关的肠道吲哚代谢物失衡可促进髓鞘再生并抑制神经炎症 | Jank, L. | N/A | Restoring the Multiple Sclerosis Associated Imbalance of Gut Indole Metabolites Promotes Remyelination and Suppresses Neuroinflammation | |
| 神经场理论作为一种框架，用于建模和理解大脑中的意识状态 | Polyakov, D. | N/A | Neural field theory as a framework for modeling and understanding consciousness states in the brain | |
| 慢波睡眠与老年人的伏隔核体积有关 | Ban, K. | N/A | Slow-wave sleep is associated with nucleus accumbens volume in elderly adults | |
| 在普通狨猴中进行的微创皮层脑电图（ECoG）记录 | Spadacenta, S. | N/A | Minimally invasive electrocorticography (ECoG) recording in common marmosets | |
| 绘制成年期全生命周期的海马体-小脑功能连接图 | Apasamy, K. | N/A | Mapping hippocampal-cerebellar functional connectivity across the adult lifespan | |
| 由局部抑制性回路调节的皮层再激活介导记忆巩固 | Lensjo, K. K. | N/A | Cortical Reactivations Modulated by Local InhibitoryCircuits Mediate Memory Consolidation | |
| 前下丘脑回路调控应激易感性 | Pennington, Z. T. | N/A | An anterior hypothalamic circuit gates stress vulnerability | |
| 屏状核对于维持工作记忆信息至关重要。 | Bhattacharjee, A. S. | N/A | The claustrum is critical for maintaining working memory information | |
| 利用个体特异的几何和连接组特征模式重建皮层功能图谱 | Olsen, A. S. | N/A | On reconstruction of cortical functional maps using subject-specific geometric and connectome eigenmodes | |
| fNIRS研究中的包容性：量化头发和皮肤特征对信号质量的影响，并提供实用的改进建议 | Yücel, M. A. | N/A | Inclusivity in fNIRS Studies: Quantifying the Impact of Hair and Skin Characteristics on Signal Quality with Practical Recommendations for Improvement | |
| 自闭症患者5-40岁期间的异常语言网络动态 | Hu, Z. | N/A | The aberrant language network dynamics in autism ages 5-40 years | |
| 在搜索过程中，通过观察工作记忆来验证潜在目标 | Wang, S. | N/A | Looking into working memory to verify potential targets during search | |
| 早期社会隔离应激诱导的自然行为变化与雌性大鼠成年期暴食行为相关 | Simon, T. B. | N/A | Shifts in Naturalistic Behaviors Induced by Early Social Isolation Stress are Associated with Adult Binge-like Eating in Female Rats | |
| 人脑新皮层中快速放电中间神经元的动作电位发放阈值降低的机制与目的 | Bakos, E. | N/A | Mechanisms and purpose of lowered action potential firing threshold in fast-spiking interneurons in the human neocortex | |
| 儿茶酚胺减少选择历史偏差 | de Gee, J. W. | N/A | Catecholamines reduce choice history biases | |
| 节奏与背景（RnB）：睡眠记录的光谱分析 | Dube, J. | N/A | Rhythms and Background (RnB): The Spectroscopy of Sleep Recordings | |
| 探索记忆回放在目标记忆再激活和鸟鸣发育中的作用：来自互补学习系统计算模型的见解 | Lu, Y. | N/A | Exploring the roles of memory replay in targeted memory reactivation and birdsong development: Insights from computational models of complementary learning systems | |
| Foxn3是调控发育中鼠视网膜纤毛基因的转录网络的一部分。 | Zhang, H. | N/A | Foxn3 is part of a transcriptional network that regulates cilia genes in the developing mouse retina | |
| Frem2敲除小鼠表现出Fraser综合征的表型，并因双侧肾发育不全而导致新生期死亡。 | Simikyan, R. G. | N/A | Frem2 Knockout Mice Exhibit Fraser Syndrome Phenotypes and Neonatal Lethality Due to Bilateral Renal Agenesis | |
| 制作神经机器人与嵌合体栉水母 | Moroz, L. L. | N/A | Making Neurobots and Chimerical Ctenophores | |
| 在捕食下的椋鸟群聚 | Papadopoulou, M. | N/A | Starling murmurations under predation | |
| 觅食关联与合作繁殖鸟类中的帮助行为有关 | Ferreira, A. C. | N/A | Foraging associations are related with helping interactions in a cooperatively breeding bird | |
| 我该留下还是离开？带有时间折扣的广义边际价值理论 | Zylberberg, J. | N/A | Should I stay or should I go? Generalized marginal value theorem with temporal discounting | |
| 温度影响果蝇同种和异种交配率 | Rader, J. A. | N/A | Temperature affects conspecific and heterospecific mating rates in Drosophila | |
| 探究生物质前体合成作为微生物适应非适应碳源的关键因素 | Cai, J. | N/A | Probing Biomass Precursor Synthesis as a Key Factor in Microbial Adaptation to Unadapted Carbon Sources | |
| FoldMark：通过水印技术保护蛋白质生成模型 | ZHANG, Z. | N/A | FoldMark: Protecting Protein Generative Models with Watermarking | |
| 利用幂后验进行突变特征的稳健发现 | Xue, C. | N/A | Robust discovery of mutational signatures using power posteriors | |
| scGenePT：语言模型是否足以模拟单细胞扰动？ | Istrate, A.-M. | N/A | scGenePT: Is language all you need for modeling single-cell perturbations? | |
| 使用突变特异性小分子激活p53Y220C | Zhu, X. | N/A | Activating p53Y220C with a Mutant-Specific Small Molecule | |
| 导致远端肾小管酸中毒的SLC4A1突变会改变胞质pH值和细胞自噬 | Essuman, G. | N/A | SLC4A1 MUTATIONS THAT CAUSE DISTAL RENAL TUBULAR ACIDOSIS ALTER CYTOPLASMIC PH AND CELLULAR AUTOPHAGY | |
| 小脑炎症与神经退行性变在新型的脊髓小脑共济失调13型小鼠模型中的关联 | Yin, J. | N/A | Association of cerebellar inflammation and neurodegeneration in a novel spinocerebellar ataxia type 13 mouse model | |
| 青少年多巴胺神经元中Grin2a的减少会导致异常的显著性和相关精神病性症状 | Kielhold, M. L. | N/A | Reductions of Grin2a in adolescent dopamine neurons confers aberrant salience and related psychosis phenotype | |
| 轻柔的曲调调教出一种新奇的长期威胁回避行为 | Aranda, M. L. | N/A | Light tunes a novel long-term threat avoidance behavior | |
| LGI1自身抗体对人类CA3锥体神经元的功能影响 | Monni, L. | N/A | The functional impact of LGI1 autoantibodies on human CA3 pyramidal neurons | |
| 减少叶酸载体1（RFC1/Slc19a1）抑制加剧成年小鼠实验性缺血性卒中中的血脑屏障破坏 | Gurler, G. | N/A | Reduced Folate Carrier 1 (RFC1/Slc19a1) Suppression Exacerbates Blood-Brain Barrier Breakdown in Experimental Ischemic Stroke in Adult Mice | |
| 微扫视强烈地调节但并不引起空间注意的N2pc脑电标记 | Liu, B. | N/A | Microsaccades strongly modulate but do not cause the N2pc EEG marker of spatial attention | |
| 酒精依赖小鼠中丘脑背内侧核的遗传和功能适应以及酒精偏向性信号传导 | Martin, J. C. | N/A | Genetic and functional adaptations and alcohol-biased signaling in the mediodorsal thalamus of alcohol dependent mice | |
| 基于结构的莱姆病亚单位疫苗设计机制性见解 | Brangulis, K. | N/A | Mechanistic insights into structure-based design of a Lyme disease subunit vaccine | |
| 被边缘案例所迷惑：当前方法能否通过机器学习实现对T细胞特异性的准确预测？ | Culka, M. | N/A | Tricked by Edge Cases: Can Current Approaches Lead to Accurate Prediction of T-Cell Specificity with Machine Learning? | |
| 小鼠植入前发育过程中mRNA翻译的时空动态和选择性 | Jiang, Z. | N/A | Spatiotemporal dynamics and selectivity of mRNA translation during mouse pre-implantation development | |
| 调整选择压力的空间分布以抑制抗性的出现 | Tunstall, T. | N/A | Tuning Spatial Distributions of Selection Pressure to Suppress Emergence of Resistance | |
| 粉蚧的多样化是由新共生体的获得引发的，随后在寄主植物上发生了适应性辐射。 | Choi, J. | N/A | The diversification of mealybugs was triggered by new symbiont acquisitions and followed by adaptive radiations on host plants | |
| 内皮细胞的硬度和类型驱动了生物力学诱导的跨细胞孔隙的形成 | Siadat, S. M. | N/A | Endothelial cell stiffness and type drive the formation of biomechanically-induced transcellular pores | |
| Genular：一个通过单细胞基因表达和多领域生物数据定义细胞身份和功能的综合平台 | Tomic, I. | N/A | Genular: An Integrated Platform for Defining Cellular Identity and Function through Single-Cell Gene Expression and Multi-Domain Biological Data | |
| DNA挂架：表面自由单分子印迹平台 | Seol, J. | N/A | DNA Hanger: Surface Free Single-Molecule Blotting Platform | |
| 单细胞蛋白质组学和转录组学表征揭示了耐药性前列腺癌细胞的分子特征与形态变化之间的关联 | Woo, J. | N/A | Single-Cell Proteomic and Transcriptomic Characterization of Drug-Resistant Prostate Cancer Cells Reveals Molecular Signatures Associated with Morphological Changes | |
| SPP1+肿瘤相关巨噬细胞通过与肿瘤微环境的相互作用诱导鼻咽癌的放疗抵抗 | Zhang, W. | N/A | SPP1+ tumor-associated macrophages induce radioresistance of nasopharyngeal carcinoma through crosstalk with the tumor microenvironment | |
| 线粒体伴侣蛋白TRAP1的点突变会影响其功能和促肿瘤活性。 | Laquatra, C. | N/A | Point mutations of the mitochondrial chaperone TRAP1 affect its functions and pro-neoplastic activity. | |
| 整合应激反应途径在肺癌中对多个免疫检查点的协调性转录调控 | Thomas-Jardin, S. | N/A | Coordinated translational control of multiple immune checkpoints by the integrated stress response pathway in lung cancer | |
| 膳食纤维调节巨噬细胞活性在结直肠癌结肠细胞-微生物相互作用微流控模型中 | Penarete-Acosta, D. | N/A | Dietary Fiber Modulates Macrophage Activity in a Microfluidic Model of Colonocyte-Microbiota Interactions in Colorectal Cancer | |
| 激素治疗前局部前列腺癌中上皮功能状态和成纤维细胞表型的分析 | Apostolov, E. | N/A | Profiling of epithelial functional states and fibroblast phenotypes in hormone therapy-naive localised prostate cancer | |
| 热中性环境对小鼠MASLD严重程度、肝基因表达及β3-肾上腺素能刺激下BAT激活的影响 | Martin, C. M. | N/A | Effect of thermoneutral housing on MASLD severity, hepatic gene expression, and BAT activation during beta3-adrenergic stimulation in mice | |
| 改变AP-1、RUNX和EGR的染色质动力学驱动纤维化肺病 | Valenzi, E. | N/A | Altered AP-1, RUNX, and EGR chromatin dynamics drive fibrotic lung disease | |
| 抗PTHrP阻断限制了CD8+ T细胞在抗癌免疫疗法中的衰竭 | Moes, B. | N/A | Anti-PTHrP blockade limits CD8+ T-cell exhaustion in anti-cancer immunotherapy | |
| 通过抗体语言模型优先掩盖非模板区域进行聚焦学习 | Ng, K. | N/A | Focused learning by antibody language models using preferential masking of non-templated regions | |
| 糖尿病-结核病共病特征为Ⅱ型干扰素减少和Th17反应增强。 | Chaudhary, S. | N/A | Diabetes-Tuberculosis Comorbidity Characterized by Reduced Type-II Interferon and Elevated Th17 Responses. | |
| 破坏G3BP1应激颗粒宿主蛋白与核衣壳（NTD-N）蛋白之间的分子相互作用会阻碍SARS-CoV-2病毒的复制。 | Dhaka, P. | N/A | Disruption of molecular interactions between G3BP1 stress granule host protein and nucleocapsid (NTD-N) protein impedes SARS-CoV-2 virus replication | |
| Oatk：一种用于复杂植物细胞器基因组从头组装的工具 | Zhou, C. | N/A | Oatk: a de novo assembly tool for complex plant organelle genomes | |
| PhenoScreen：一种基于双空间对比学习框架的表型筛选方法，通过将化学扰动与细胞形态联系起来 | Wang, S. | N/A | PhenoScreen: A Dual-Space Contrastive Learning Framework-based Phenotypic Screening Method by Linking Chemical Perturbations to Cellular Morphology | |
| 内在无序的Qβ衣壳蛋白与含发夹RNA形成多相RNP颗粒 | Granik, N. | N/A | Formation of polyphasic RNP granules by intrinsically disordered Qβ coat proteins and hairpin-containing RNA | |
| 多巴胺调控秀丽隐杆线虫对锰诱导的多巴胺能神经毒性的敏感性。 | Raj, V. | N/A | Dopamine controls the Sensitivity to Manganese induced Dopaminergic neurotoxicity in Caenorhabditis elegans | |
| 棕色脂肪组织产热节律是由视交叉上核驱动的，与脂肪细胞时钟无关。 | Paschos, G. K. | N/A | Brown adipose tissue thermogenesis rhythms are driven by the SCN independent of adipocyte clocks | |
| 通过免疫信息学分析进行的多表位疫苗的计算机设计，用于对抗蜱传脑炎病毒 | Wang, B. | N/A | In silico design of a multi-epitope vaccine against tick-borne encephalitis virus via immunoinformatic analysis | |
| 对来自全球多源的克雷伯氏菌变种菌株进行基因组分析，揭示了与人类感染相关的适应性特征。 | Wang, J. | N/A | Genome Analyses of A Worldwide Multisource Collection of Klebsiella variicola Reveal Adaptation Relevant for Human Infection | |
| 剪接因子激酶，即SR蛋白激酶1（SRPK1），对于人乳头瘤病毒生命周期的后期事件至关重要。 | Faizo, A. A. A. | N/A | The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycle. | |
| CRISPR技术对基因表达的调控，决定了微生物甲烷的同位素组成。 | Gropp, J. | N/A | CRISPR-enabled control of gene expression sets the isotopic composition of microbial methane | |
| Tad菌毛ATP酶CpaF中的协调构象变化促进了催化旋转机制 | Yen, I. Y. | N/A | Coordinated conformational changes in the Tad pilus ATPase CpaF facilitate a rotary mechanism of catalysis | |
| 复杂系统建模揭示，草酸盐稳态是由多种草酸盐降解细菌驱动的。 | Mukherjee, S. D. | N/A | Complex system modelling reveals oxalate homeostasis is driven by diverse oxalate-degrading bacteria | |
| 在生命周期中，牛奶草虫Oncopeltus fasciatus的种内微生物群动态变化 | Larner, W. | N/A | Intraspecific microbiome dynamics across the life cycle of the milkweed bug Oncopeltus fasciatus | |
| 通过哺乳动物乙型肝炎病毒X蛋白实现的保守但差异化的Smc5/6复合物降解 | Shofa, M. | N/A | Conserved yet Divergent Smc5/6 Complex Degradation by Mammalian Hepatitis B Virus X Protein | |
| 通过哺乳动物乙型肝炎病毒X蛋白实现的保守但分化的Smc5/6复合物降解 | Shofa, M. | N/A | Conserved yet Divergent Smc5/6 Complex Degradation by Mammalian Hepatitis B Virus X Proteins | |
| 伯氏疏螺旋体在培养的静止期会失去重要的遗传元件和细胞增殖潜力，但在蜱虫媒介中则不会。 | Zhang, J. | N/A | Borrelia burgdorferi loses essential genetic elements and cell proliferative potential during stationary phase in culture but not in the tick vector. | |
| 通过增加槲皮素（一种黄酮类化合物）的生物利用度，诱导产生一种协同的抗肥胖效果，这一过程由一种植物乳杆菌（L. plantarum）菌株实现。 | Kang, Y.-G. | N/A | Inducing a synergistic anti-obesity effect by increasing the bioavailability of the flavonoid rutin with a L. plantarum species | |
| 前列腺特异性膜受体PPAP通过FimH结合促进大肠杆菌入侵前列腺腔细胞 | Guedes, M. | N/A | Prostate-specific membrane receptor PPAP facilitates E. coli invasion of luminal prostate cells via FimH binding | |
| 转录因子Sfp1与NuA4复合体在应对营养物质可利用性方面的功能性相互作用 | Xu, K. | N/A | Functional interaction between transcription factor Sfp1 and the NuA4 complex in response to nutrient availability | |
| 一种从纯化到冻干递送的环状RNA治疗完整方案，采用新型可离子化脂质 | Broset, E. | N/A | A complete approach for circRNA therapeutics from purification to lyophilized delivery using novel ionizable lipids | |
| 天然产物生物合成中假定末端酰胺化域的结构 | Rankin, M. R. | N/A | Structure of a Putative Terminal Amidation Domain in Natural Product Biosynthesis | |
| 可溶性鸟苷酸环化酶（NO受体）通过其转亚硝基化活性调节内皮依赖性血管舒张。 | Younis, W. | N/A | Soluble guanylyl cyclase, the NO-receptor, regulates endothelium-dependent vascular relaxation via its transnitrosation activity. | |
| 唤醒原初编辑技术：精准工程改造益生菌大肠杆菌Nissle 1917 | Chen, P.-R. | N/A | Awakening prime editing for precision engineering of probiotic Escherichia coli Nissle 1917 | |
| 转录调控和位点特异性生物化学的组合效应器靶向（COMET） | Wilson, C. M. | N/A | Combinatorial effector targeting (COMET) for transcriptional modulation and locus-specific biochemistry | |
| 使用大型语言模型操作无细胞生物铸造厂 | Herisson, J. | N/A | Operate a Cell-Free Biofoundry using Large Language Models | |
| 从微RNA表达数据中定量设计细胞类型特异性mRNA稳定性 | Oesinghaus, L. | N/A | Quantitative design of cell type-specific mRNA stability from microRNA expression data | |
| 运动细菌群体中空间模式转变的机制 | Saulnier, J.-B. | N/A | The mechanism of spatial pattern transition in motile bacterial collectives | |
| 跨灵长类基因组筛选包膜基因揭示内源性逆转录病毒的进化和多样性模式 | Chabukswar, S. | N/A | Screening Envelope Genes Across Primate Genomes Reveals Evolution and Diversity Patterns of Endogenous Retroviruses | |
| 迈向完整的噬菌体尾部纤维结构图谱。 | Klein-Sousa, V. | N/A | Towards a complete phage tail fiber structure atlas. | |
| 蓝细菌辅因子非依赖型磷酸甘油酸变位酶的结构元件，介导PirC调控 | Orthwein, T. | N/A | Structural elements of cyanobacterial co-factor-independent phosphoglycerate mutase that mediate regulation by PirC | |
| 铜绿假单胞菌抵抗VI型分泌系统攻击的机制 | Tejada-Arranz, A. | N/A | Mechanisms of P. aeruginosa resistance to Type VI Secretion System attacks | |
| 利用鸡胚绒毛尿囊膜模型评估肿瘤定植沙门氏菌株 | Kenney, L. J. | N/A | Evaluation of Tumor-colonizing Salmonella Strains using the Chick Chorioallantoic Membrane Model | |
| 单细胞代谢动力学的回溯分析可预测细菌在人体巨噬细胞中的复制 | Drame, M. | N/A | Backtracking Metabolic Dynamics in Single Cells Predicts Bacterial Replication in Human Macrophages | |
| NACHO介导的五聚配体门控离子通道组装机制 | Hooda, Y. | N/A | Mechanism of NACHO-mediated assembly of pentameric ligand-gated ion channels | |
| 动态RNA结合与无义介导的mRNA降解因子UPF2的展开 | Szeto, J.-Y. A. | N/A | Dynamic RNA binding and unfolding by nonsense-mediated mRNA decay factor UPF2 | |
| 邻近相互作用组分析揭示了IRE1a经典信号通路的新调控因子 | Le Goupil, S. | N/A | Proximity Interactome analyses unveil novel regulators of IRE1a canonical signaling | |
| Neuroligin 3突显了果蝇社交间隔中的性别二态性回路 | Robinson, J. W. | N/A | Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing | |
| # BioRxiv 2024-10-27 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 慢振荡-纺锤波耦合预测基于序列的语言学习 | Cross, Z. R. | N/A | Slow oscillation-spindle coupling predicts sequence-based language learning | |
| 周期环境中的共存 | Scott, A. M. | N/A | Coexistence in Periodic Environments | |
| 通过AAV外显子测序的CRISPR筛选（CrAAVe-seq）是一种高度可扩展的细胞类型特异性体内筛选平台。 | Ramani, B. | N/A | CRISPR screening by AAV episome-sequencing (CrAAVe-seq) is a highly scalable cell type-specific in vivo screening platform | |
| 在巩固过程中，部分多巴胺能神经元的活动短暂中断，会通过破坏睡眠来损害长期记忆。 | Yan, L. | N/A | Brief disruption of activity in a subset of dopaminergic neurons during consolidation impairs long-term memory by fragmenting sleep | |
| ExploreTurns：一种用于探索、分析和分类蛋白质中beta转角和结构化环的网络工具；应用于beta凸起环、Schell曼环、Asx螺旋帽、beta发夹及其他氢键连接基序 | Newell, N. E. | N/A | ExploreTurns: A web tool for the exploration, analysis, and classification of beta turns and structured loops in proteins; application to beta-bulge and Schellman loops, Asx helix caps, beta hairpins and other hydrogen-bonded motifs | |
| 非人类灵长类动物中决策与运动相互作用但解耦控制的证据 | Saleri, C. | N/A | Evidence for interacting but decoupled controls of decisions and movements in non-human primates | |
| 人道主义背景下无性繁殖作物面临的病原体和害虫风险：为喀麦隆和埃塞俄比亚制定国家植物健康风险分析 | Mouafo-Tchinda, R. | N/A | Pathogen and pest risks to vegetatively propagated crops in humanitarian contexts: Towards a national plant health risk analysis for Cameroon and Ethiopia | |
| Dravet综合征Scn1a+/-小鼠的神经发育缺陷：靶向GABA开关可挽救行为功能障碍，但不能改善癫痫发作和死亡率。 | Pizzamiglio, L. | N/A | Neurodevelopmental defects in Dravet syndrome Scn1a+/- mice: targeting GABA-switch rescues behavioral dysfunctions but not seizures and mortality. | |
| 3DCellComposer - 一种利用2D细胞分割方法进行3D细胞分割的多功能管道 | Chen, H. | N/A | 3DCellComposer - A Versatile Pipeline Utilizing 2D Cell Segmentation Methods for 3D Cell Segmentation | |
| 婴儿脑电图中眼球运动伪迹的校正 | Srishyla, D. | N/A | Eye-movement artifact correction in infant EEG | |
| 从背外侧前额叶皮层的转录组和表观基因组数据推断阿尔茨海默病女性患者的潜在多重疾病进展途径 | Honda, K. | N/A | Potential multiple disease progression pathways in female patients with Alzheimer's disease inferred from transcriptome and epigenome data of the dorsolateral prefrontal cortex | |
| 利用生成式人工智能方法推进多器官毒性评估的跨器官转录组学研究 | Li, T. | N/A | Bridging Organ Transcriptomics for Advancing Multiple Organ Toxicity Assessment with a Generative AI Approach | |
| MGPfactXMBD：一种基于模型的分解方法，用于单细胞RNA数据，揭示了细胞命运决定背后的分叉转录模块 | Ren, J. | N/A | MGPfactXMBD: A Model-Based Factorization Method for scRNA Data Unveils Bifurcating Transcriptional Modules Underlying Cell Fate Determination | |
| 杀婴行为是由对后代位置的不熟悉所驱动的，并与模仿毒蛙中的雄激素变化相关联。 | Lewis, A. R. | N/A | Infanticide is driven by unfamiliarity with offspring location and associated with androgenic shifts in mimic poison frogs | |
| 鲁迪拉介导的微管稳定性调控在小鼠血管发育过程中TGFβ信号传导 | Joshi, D. | N/A | Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development | |
| 优先处理工作记忆资源取决于前额叶皮层 | Hallenbeck, G. E. | N/A | Prioritizing working memory resources depends on prefrontal cortex | |
| 寄生虫释放的敌对力量在入侵的非洲无花果蝇（Zaprionus indianus）中是情境依赖的。 | Walsh-Antzak, C. R. | N/A | Strength of enemy release from parasitoids is context-dependent in the invasive African Fig Fly, Zaprionus indianus | |
| 禽源沙门氏菌肠炎沙门氏菌血清型鸡白痢向地方性转变的过程中伴随着局部抗性组和移动组的相互作用。 | Jia, C. | N/A | Avian-specific Salmonella enterica Serovar Gallinarum transition to endemicity is accompanied by localized resistome and mobilome interaction | |
| 长寿的软骨祖细胞由胎儿肢体的Gli1+细胞产生，并在软骨中的镶嵌细胞周期停滞时得到补充。 | Qu, X. | N/A | Long-lived chondroprogenitors are generated by fetal-limb Gli1+ cells and are replenished upon mosaic cell-cycle arrest in the cartilage | |
| 全原子连续恒定pH分子动力学的力场限制 | Peeples, C. | N/A | Force Field Limitations of All-Atom Continuous Constant pH Molecular Dynamics | |
| 人类4D核组结构与功能的综合视角 | The 4D Nucleome Consortium, | N/A | An integrated view of the structure and function of the human 4D nucleome | |
| 氯胺酮通过在小鼠中表达钙离子通透性AMPA受体来逆转慢性应激引起的行为变化。 | Flowers, J. C. | N/A | Ketamine reverses chronic stress-induced behavioral changes via the expression of Ca2+-permeable AMPA receptors in mice | |
| 免疫-病原体共进化中的信息处理适应性效率 | Bellamy, Q. N. | N/A | Adaptive efficiency of information processing in immune-pathogen co-evolution | |
| 自由觅食的猕猴在模糊地形中重视信息 | Shahidi, N. | N/A | Freely foraging macaques value information in ambiguous terrains | |
| 单个癌细胞中多种ecDNA类型的维持 | Scanu, E. | N/A | The maintenance of multiple ecDNA types in single cancer cells | |
| 前脑岛中的多巴胺传递塑造了焦虑的神经编码 | COUDERC, Y. | N/A | Dopamine transmission in the anterior insula shapes the neural coding of anxiety | |
| 停留时间对视觉和被动导入运动情境效应的影响 | Alvarez-Hidalgo, L. | N/A | The impact of dwell time on the contextual effect of visual and passive lead-in movements | |
| 抑制RNA调节因子HuR可有效缓解脊髓损伤，通过强力抑制损伤后的神经炎症。 | Husain, M. A. | N/A | Inhibition of the RNA Regulator HuR mitigates spinal cord injury by potently suppressing post-injury neuroinflammation | |
| 后顶叶皮层介导由稀有性引发的决策偏差及不确定性下的学习 | Sheng, W. | N/A | Posterior parietal cortex mediates rarity-induced decision bias and learning under uncertainty | |
| UBA5抑制剂的鉴定与表征 | Singh, V. | N/A | Identification and characterization of UBA5 inhibitors | |
| 计算识别空间转录组学数据中的迁移T细胞 | Zhong, L. | N/A | Computational Identification of Migrating T cells in Spatial Transcriptomics Data | |
| 基于特征的注意在人类皮层下核团功能分区中的空间全局效应 | Lin, W. | N/A | Spatially global effects of feature-based attention in functional subdivisions of human subcortical nuclei | |
| 通过祖先X-Y染色体基因对Kdm5c-Kdm5d调控性别偏向基因表达 | Malcore, R. M. | N/A | Regulation of Sex-biased Gene Expression by the Ancestral X-Y Chromosomal Gene Pair Kdm5c-Kdm5d | |
| 非洲起源的单体型对APOEϵ4携带者的阿尔茨海默病具有保护作用：探索潜在机制 | Bertholim-Nasciben, L. | N/A | African origin haplotype protective for Alzheimer's disease in APOEϵ4 carriers: exploring potential mechanisms | |
| CD90识别出具有不同激活和静息维持模式的肌肉干细胞的不同亚群。 | Kheir, E. | N/A | CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance | |
| 景天酸代谢在CAM植物Kalanchoë laxiflora中的蛋白质水平调控 | Schiller, K. | N/A | Regulation of Crassulacean Acid Metabolism at the protein level in the CAM plant Kalanchoë laxiflora | |
| DNA甲基化年龄生物标志物具有响应性：来自51项人类长寿干预研究的见解 | Sehgal, R. | N/A | DNAm aging biomarkers are responsive: Insights from 51 longevity interventional studies in humans | |
| 室旁核中的Apelin-13通过室旁核的V1a受体和孤束核的GABAA受体γ2保护大鼠心肌免受缺血损伤。 | yan, w. | N/A | Apelin-13 in the paraventricular nucleus protects myocardium from ischemia via V1a receptor of the paraventricular nucleus and GABAA receptor γ2 of the nucleus tractus solitarii in rats | |
| 多发性硬化脊髓中的异常铁沉积与神经退行性变有关 | Pisa, M. | N/A | Aberrant iron deposition in the multiple sclerosis spinal cord relates to neurodegeneration | |
| 训练刺激的复杂特性影响深度网络模型中大脑视觉皮层的对齐 | Torabian, P. | N/A | Complex Properties of Training Stimuli Affect Brain Alignment in a Deep Network Model of Mouse Visual Cortex | |
| 脂质氢同位素组成主要反映了模式古菌Sulfolobus acidocaldarius的生长水。 | Harris, C. M. | N/A | Lipid hydrogen isotope compositions primarily reflect growth water in the model archaeon Sulfolobus acidocaldarius | |
| HIV-1包膜糖蛋白原体的化学计量学及其稳定或破坏预触发构象的变化 | Zhang, Z. | N/A | Stoichiometry of HIV-1 Envelope Glycoprotein Protomers with Changes That Stabilize or Destabilize the Pretriggered Conformation | |
| NLGN3通过激活Gαi1/3-Akt通路促进心肌梗死中的血管生成 | qiao, s. | N/A | NLGN3 contributes to angiogenesis in myocardial infarction via activation of the Gαi1/3-Akt Pathway | |
| 旁观者碱基编辑干扰了莱伯先天性黑蒙视觉功能的恢复 | Lee, S.-H. | N/A | Bystander base editing interferes with visual function restoration in Leber congenital amaurosis | |
| 一种新型雄性附腺肽降低了褐飞虱雌性交配后的接受性 | Zhang, Y.-J. | N/A | A novel male accessory gland peptide reduces female post-mating receptivity in the brown planthopper | |
| 一夜部分睡眠剥夺对血管周围空间体积分数的影响：来自斯德哥尔摩困倦大脑研究的发现 | Custer, R. M. | N/A | Effects of one-night partial sleep deprivation on perivascular space volume fraction: Findings from the Stockholm Sleepy Brain Study | |
| 皮层6b层介导了与状态相关的大脑活动变化，以及食欲素对觉醒和睡眠的影响。 | Meijer, E. J. | N/A | Cortical layer 6b mediates state-dependent changes in brain activity and effects of orexin on waking and sleep | |
| 低剂量的A型和B型肉毒杆菌神经毒素有利于沙门氏菌和志贺氏菌的感染，而不会引起肉毒中毒的松弛性麻痹。 | Fabris, F. | N/A | Low Intestinal Doses of Botulinum Neurotoxins types A and B favour infection by Salmonella and Shigella without the flaccid paralysis of botulism | |
| 斑马鱼中个体保守神经元微外显子的表型影响及其主调控因子 | Lopez-Blanch, L. | N/A | Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish | |
| Foxi1通过转录和表观遗传机制调控粘液纤毛发育和离子细胞分化的多个步骤 | Bowden, S. | N/A | Foxi1 regulates multiple steps of mucociliary development and ionocyte specification through transcriptional and epigenetic mechanisms | |
| NOTCH1驱动肝细胞癌的肿瘤可塑性和转移 | Lindblad, K. E. | N/A | NOTCH1 drives tumor plasticity and metastasis in hepatocellular carcinoma | |
| 一种结合计算模型，用于模拟癌症球体生长，涉及核糖诱导的胶原蛋白硬化 | Botticelli, M. | N/A | A hybrid computational model of cancer spheroid growth with ribose-induced collagen stiffening | |
| 特定领域的模式重用在灵长类大脑中支持灵活的学习 | Tian, K. | N/A | Domain-specific Schema Reuse Supports Flexible Learning to Learn in Primate Brain | |
| 分泌型Clever-1调节T细胞反应并影响癌症免疫治疗效果 | Prince, S. | N/A | Secreted Clever-1 Modulates T Cell Responses and Impacts Cancer Immunotherapy Efficacy | |
| 马达聚类增强驱动囊泡运输 | Jiang, R. | N/A | Motor Clustering Enhances Kinesin-driven Vesicle Transport | |
| 利用人工智能自动化检测和量化染色体外DNA（ecDNA）以解码药物反应 | Goble, K. | N/A | Leveraging AI to Automate Detection and Quantification of Extrachromosomal DNA (ecDNA) to Decode Drug Responses | |
| 探索以丙酮酸为唯一碳源的细菌培养基的生化环境，用于核磁共振研究 | Dag, C. | N/A | Exploring the Biochemical Landscape of Bacterial Medium with Pyruvate as the Exclusive Carbon Source for NMR Studies | |
| 优化复杂RNA系统的即时概率增强采样：采样H型假结的自由能表面 | Malekzadeh, K. | N/A | Optimizing On-the-Fly Probability Enhanced Sampling for Complex RNA Systems: Sampling Free Energy Surfaces of an H-Type Pseudoknot | |
| 生态上截然不同的微生物群落降解有机物一致地促进植物生长 | Lee, B. | N/A | Degradation of organic matter by ecologically distinct microbiomes uniformly promotes plant growth | |
| 果糖激活了链球菌突变体中与甲基乙二醛和过氧化氢共享的应激反应 | Walker, A. R. | N/A | FRUCTOSE ACTIVATES A STRESS RESPONSE SHARED BY METHYLGLYOXAL AND HYDROGEN PEROXIDE IN STREPTOCOCCUS MUTANS | |
| 密螺旋体牙龈卟啉单胞菌穿梭质粒中蛋白质表达的功能表征与优化 | Goetting-Minesky, M. P. | N/A | Functional characterization and optimization of protein expression in Treponema denticola shuttle plasmids | |
| 鲍曼不动杆菌的防御体系揭示了根据其先天防御系统和噬菌体特征划分的两个基因组群体。 | Moreno-Rodriguez, A. | N/A | The defensome of Acinetobacter baumannii reveals two genome groups according to their innate defense systems and phage profile | |
| 病毒进入是单核细胞中人巨细胞病毒潜伏的主要决定因素 | Kitsberg, Y. | N/A | Virus Entry is a Major Determinant of HCMV Latency in Monocytes | |
| 针对ADORA-PDE10 cAMP微域：肺动脉高压的新型治疗策略 | Valasarajan, C. | N/A | Targeting ADORA-PDE10 cAMP Microdomain: A Novel Therapeutic Approach for Pulmonary Hypertension | |
| 比较元转录组学揭示了浮游动物对生活环境中营养异质性的生理反应 | Nuruddin, M. F. | N/A | Comparative meta transcriptomics uncovers the physiological responses of zooplankton to nutrient heterogeneity in their living environment | |
| 整合的肝铁死亡基因特征决定了铁死亡的致病特征 | Matsumoto, T. | N/A | Integrated hepatic ferroptosis gene signature dictates pathogenic features of ferroptosis | |
| 细菌接种可调控珊瑚的表观基因组 | Barno, A. R. | N/A | Bacterial inoculation manipulates the coral epigenome | |
| 利用16S纳米孔测序增强海底生态状态预测 | Philip, M. | N/A | Enhanced Prediction of Seafloor Ecological State Using 16S Nanopore Sequencing | |
| 飞行哺乳动物Rhinolophus hipposideros的配子散布几何结构 | Brazier, T. | N/A | The geometry of gametic dispersal in a flying mammal, Rhinolophus hipposideros | |
| 伯氏疏螺旋体感染的肩突硬蜱中的表观遗传反应：常染色质组蛋白赖氨酸甲基转移酶2的过表达及DNA甲基化无变化 | MacIntosh, G. H. | N/A | Epigenetic responses in Borrelia-infected Ixodes scapularis ticks: Over-expression of euchromatic histone lysine methyltransferase 2 and no change in DNA methylation | |
| 低覆盖率测序工作流程在茄子精准基因分型中的基准测试 | Baraja-Fonseca, V. | N/A | Benchmarking of Low Coverage Sequencing Workflows for Precision Genotyping in Eggplant | |
| 六倍体燕麦的泛基因组和泛转录组 | Avni, R. | N/A | A pangenome and pantranscriptome of hexaploid oat | |
| 巨型鳞翅目昆虫古共生体中加速的假基因化 | Choi, J. | N/A | Accelerated pseudogenization in ancient endosymbionts of giant scale insects | |
| 环状RNA AEBP2：树突状细胞发育中的新型调控因子 | Zhou, Q. | N/A | Circular RNA AEBP2: A novel regulator in dendritic cell development | |
| 利用拓扑机器学习识别靶向细菌丙酸代谢的分子化合物 | Tola, A. | N/A | Identification of Molecular Compounds Targeting Bacterial Propionate Metabolism with Topological Machine Learning | |
| 可以利用mTOR-Tfeb-Fabp7a信号轴来改善成年斑马鱼中的bag3心肌病 | Ding, Y. | N/A | An mTOR-Tfeb-Fabp7a signaling axis can be harnessed to ameliorate bag3 cardiomyopathy in adult zebrafish | |
| 剖析转座元件对间期染色体结构的贡献 | Shi, L. | N/A | Dissecting the Contribution of Transposable Elements to Interphase Chromosome Structure | |
| 翻译：翻译后修饰调控孤儿受体GPR52的固有信号偏倚 | Zhang, B. | N/A | Post-translational modifications orchestrate the intrinsic signaling bias of orphan receptor GPR52 | |
| 去氨甲酰化和未去氨甲酰化的eIF5A异构体在胰腺发育和功能模型中表现出不同的作用 | Anderson, C. M. | N/A | Hypusinated and unhypusinated isoforms of eIF5A exert distinct effects in models of pancreas development and function | |
| PXGS：一种基于Dscam互斥剪接的多基因表达系统 | Yu, R. Y. | N/A | PXGS: a Poly-Transgene Expression System based on Mutually Exclusive Splicing of Dscam | |
| 基因组范围内遗传扰动的相分离景观 | Heidenreich, M. | N/A | The phase separation landscape of genome-wide genetic perturbations | |
| 肌动蛋白调节因子的时空协调作用在细胞融合过程中产生侵袭性突起 | Lu, Y. | N/A | Spatiotemporal coordination of actin regulators generates invasive protrusions in cell-cell fusion | |
| IGF2通过介导Hippo信号通路来控制肝脏大小 | Zhong, Z. | N/A | IGF2 mediates Hippo signaling to control liver size | |
| 全面蛋白质组学表征高尔基体内部运输中间体 | Sumya, F. T. | N/A | Comprehensive Proteomic Characterization of Intra-Golgi Trafficking Intermediates | |
| 线粒体自噬调节在秀丽隐杆线虫（C. elegans）的uaDf5动物模型中，能够缓解单一大规模线粒体DNA缺失（SLSMD）疾病的症状。 | Mendel, R. M. | N/A | Mitophagy modulation rescues single large-scale mitochondrial DNA deletion (SLSMD) disease symptoms in the C. elegans uaDf5 animal model. | |
| 通过表型药物筛选和药物设计开发新型黄酮类衰老细胞清除剂 | Zhang, L. J. | N/A | Development of novel flavonoid senolytics through phenotypic drug screening and drug design | |
| 在受控流动条件下对芯片器官进行系统标准化：以Caki-1和A549细胞系为例的应用案例 | Balsa-Diaz, A. | N/A | Systematic standardization of organ-on-a-chip under controlled flow conditions: use case with Caki-1 and A549 cell lines | |
| # BioRxiv 2024-10-26 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 脑岛和颞上沟在社交决策中对人际内疚感和责任感的贡献 | Gaedeke, M. | N/A | Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions | |
| 一项关于拉尔氏菌复合体已知全球分布和宿主范围的元分析 | Lowe-Power, T. | N/A | A Meta-analysis of the known Global Distribution and Host Range of the Ralstonia Species Complex | |
| 系统性降钙素基因相关肽（CGRP）可修饰听觉和前庭终器的电位，并增加感觉超敏性。 | Rahman, S. M. | N/A | Systemic Calcitonin Gene-Related Peptide (CGRP) modifies auditory and vestibular end organ electrical potentials, and increases sensory hypersensitivities | |
| 利用果蝇探究多细胞生物多聚磷酸盐生物学：揭示新颖且保守的多聚磷酸盐功能 | Sarkar, S. | N/A | Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions | |
| 在鼠类成纤维细胞中，微管的全球排列和局部曲率对于波形蛋白和肌动蛋白的扰动具有较强的稳健性。 | Blob, A. | N/A | Global alignment and local curvature of microtubules in mouse fibroblasts are robust against perturbations of vimentin and actin | |
| 巨噬细胞特异性脂质纳米颗粒疗法通过巨噬细胞-上皮相互作用阻断肺部机械敏感性免疫 | Mthunzi, L. | N/A | Macrophage-specific lipid nanoparticle therapy blocks the lungs mechanosensitive immunity due to macrophage-epithelial interactions | |
| 大型生物银行队列中随访数据的分析：方法学综述 | Kolde, A. | N/A | Analysis of follow-up data in large biobank cohorts: a review of methodology | |
| 在诱导多能干细胞衍生的神经元中进行的CRISPR筛选揭示了tau蛋白稳态的原理 | Samelson, A. J. | N/A | CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis | |
| 邻域内相关性在植物间相互作用中的作用：对黑杨高度生长和锈病损害的影响 | Tiret, M. | N/A | The role of relatedness within a neighborhood in plant-to-plant interaction: effect on height growth and rust damage in Populus nigra | |
| 炎症小体主要限制了胞质内沙门氏菌在人类巨噬细胞中的复制 | Egan, M. S. | N/A | Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages | |
| 火烈鸟参与多种细胞竞争模式 | Bosch, P. S. | N/A | Flamingo participates in multiple models of cell competition | |
| ATP释放的缝隙连接通道受溶血磷脂调控 | Henze, E. | N/A | ATP-release pannexin channels are gated by lysophospholipids | |
| 扩张型心肌病相关RNA结合基序蛋白20调控神经元中的长前体mRNA | Di Bartolomei, G. | N/A | Dilated cardiomyopathy-associated RNA Binding Motif Protein 20 regulates long pre-mRNAs in neurons | |
| 休息期间的记忆巩固会在认知地图中形成捷径 | Shearer, C. M. | N/A | Memory consolidation during rest forms shortcuts in a cognitive map | |
| ABC转运蛋白BmrA的构象变化依赖于膜曲率 | Damm, A. | N/A | Conformational changes of the ABC Transporter BmrA Depend on Membrane Curvature | |
| 多样执行功能全基因组关联研究的基因组SEM模型提高了基因发现 | Perry, L. C. | N/A | GenomicSEM Modelling of Diverse Executive Function GWAS Improves Gene Discovery | |
| 克服“饥饱”效应：全基因组关联研究中的改进交互测试 | Zhou, H. | N/A | Overcoming the "feast or famine" effect: improved interaction testing in genome-wide association studies | |
| 慢性血栓栓塞性肺动脉高压中肺血管树的内皮特征：独特还是共有的方面？ | Verhaegen, J. | N/A | Endothelial features along the pulmonary vascular tree in chronic thromboembolic pulmonary hypertension: distinctive or shared facets? | |
| 环节动物幼虫的全身体连接组 | Veraszto, C. | N/A | Whole-body connectome of a segmented annelid larva | |
| 18种人类癌症基因表达的深度分析 | Qiu, W. | N/A | A deep profile of gene expression across 18 human cancers | |
| 自噬蛋白ATG14通过防止非计划性细胞焦亡的激活，在早期妊娠期间确保胚胎运输的安全进行。 | POPLI, P. | N/A | The autophagy protein, ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy | |
| 角质形成细胞中Semaphorin 4A的下调反映了非皮损性银屑病的特征。 | Kume, M. | N/A | Downregulation of Semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis | |
| Nicheformer：单细胞和空间组学的基石模型 | Schaar, A. C. | N/A | Nicheformer: a foundation model for single-cell and spatial omics | |
| 在羊膜动物原肠胚形成过程中，左右组织形成之前，双侧细胞流动显示出不对称性。 | Asai, R. | N/A | Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation | |
| 高加索侏儒虾虎鱼（Knipowitschia cf. caucasica）染色体水平基因组参考，这是一种新入侵莱茵河的虾虎鱼科外来物种 | Schoenle, A. | N/A | Chromosome level genome reference of the Caucasian dwarf goby Knipowitschia cf. caucasica, a new alien Gobiidae invadingthe River Rhine | |
| 评估用于非靶向代谢组学的提取溶剂，以解析南极冰岩洞中溶解有机物的成分 | Mundhe, S. D. | N/A | Evaluation of extraction solvents for untargeted metabolomics to decipher the dissolved organic matter of Antarctic cryoconite holes | |
| 青蒿琥酯、EDTA和多粘菌素联合作用对MCR阴性和阳性的多粘菌素耐药沙门氏菌具有协同抗菌效果。 | Zhai, Y. | N/A | Artesunate, EDTA and colistin work synergistically against MCR-negative and -positive colistin-resistant Salmonella | |
| 执行资源塑造了语言可预测性在整个成年期内的影响 | Schuckart, M. M. | N/A | Executive Resources Shape the Effects of Language Predictability Across the Adult Lifespan | |
| 开放通道液滴微流控平台用于被动生成人类精子微滴 | Nicholson, T. M. | N/A | Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets | |
| 在颜色不显眼的青蛙中被动积累生物碱，精炼了后天化学防御的进化范式。 | Tarvin, R. D. | N/A | Passive accumulation of alkaloids in inconspicuously colored frogs refines the evolutionary paradigm of acquired chemical defenses | |
| 幅度熵用于捕捉癫痫发作期间脑动力学改变中的类嵌合体行为 | Ghosh, S. | N/A | Amplitude entropy to capture chimera-like behavior in the altered brain dynamics during seizures | |
| 稀疏标注足以用于启动密集分割的训练 | Thiyagarajan, V. V. | N/A | Sparse Annotation is Sufficient for Bootstrapping Dense Segmentation | |
| 优化One-Pot PURE系统中的蛋白质生产：对反应组成和表达效率的见解 | Zhang, Y. | N/A | Optimizing protein production in the One-Pot PURE system: insights into reaction composition and expression efficiency | |
| 镁通过调节磷脂代谢促进细菌对抗生素的表型抗性 | Li, H. | N/A | Magnesium modulates phospholipid metabolism to promote bacterial phenotypic resistance to antibiotics | |
| TissueViewer：基于网络的多重图像查看器 | van IJzendoorn, D. G. P. | N/A | TissueViewer: A Web-Based Multiplexed Image Viewer | |
| 生态进化引导的路径组学分析用于预测DCIS升级 | Xiao, Y. | N/A | Eco-evolutionary Guided Pathomic Analysis to Predict DCIS Upstaging | |
| GlyT2阳性中间神经元调控小脑-行为回路中信息传递的时间和变异性 | Palacios, E. R. | N/A | GlyT2-positive interneurons regulate timing and variability of information transfer in a cerebellar-behavioural loop | |
| “微离线收益”对运动技能学习没有益处 | Das, A. | N/A | "Micro-offline gains" convey no benefit for motor skill learning | |
| NF-κB表观遗传吸引子景观驱动乳腺癌异质性 | Lopes, F. J. P. | N/A | NF-κB Epigenetic Attractor Landscape Drives Breast Cancer Heterogeneity | |
| 流感病毒感染经历会改变肺结构细胞的动态，从而在病毒再次挑战后迅速获得免疫保护。 | Worrell, J. C. | N/A | Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge | |
| 流感病毒感染经历会改变肺结构细胞的动态，从而在病毒再次挑战后迅速获得免疫保护。 | Worrell, J. C. | N/A | Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge | |
| 苏云金芽孢杆菌库尔斯塔克亚种施用对加拿大东部北方森林中非目标夜行性大蛾生物多样性的影响。 | Young, J. O. | N/A | Effects of Bacillus thuringiensis subsp. kurstaki application on non-target nocturnal macromoth biodiversity in the eastern boreal forest, Canada. | |
| 巴西大西洋森林中不同土地覆盖类型的相对易燃性 | Adorno, B. F. | N/A | Relative fire-proneness of land cover types in the Brazilian Atlantic Forest | |
| 链藻类NMCP类核纤层蛋白的结构多样性与分布 | Kosztyo, B. S. | N/A | Structural diversity and distribution of NMCP-class nuclear lamina proteins in streptophytic algae | |
| 距离预测的神经表征精度与算术表现相关 | Zhao, H. | N/A | Neural Representation Precision of Distance Predicts Arithmetic Performance | |
| 转录因子Chronophage/BCL11A/B促进肠干细胞增殖和内分泌分化 | King, E. A. | N/A | The transcription factor Chronophage/BCL11A/B promotes intestinal stem cell proliferation and endocrine differentiation | |
| 人类遗传祖先、结核分枝杆菌多样性与坦桑尼亚达累斯萨拉姆市结核病严重程度的关系 | Zwyer, M. | N/A | Human genetic ancestry, Mycobacterium tuberculosis diversity and tuberculosis disease severity in Dar es Salaam, Tanzania | |
| 体内抗体标记途径和荧光染料决定了标记效率、灵敏度和持久性 | Hagan, N. B. | N/A | In vivo antibody labeling route and fluorophore dictate labeling efficiency, sensitivity, and longevity | |
| 快速且准确的LSTM元建模体外TNF诱导的肿瘤抗性 | Abrate, M. P. | N/A | Fast and Accurate LSTM Meta-modeling of TNF-induced Tumor Resistance In Vitro | |
| RRx-001在实验性子宫内膜异位症小鼠模型中的临床前测试显示出有前景的治疗效果。 | McIntyre, I. | N/A | Preclinical testing of RRx-001 in mouse models of experimental endometriosis reveals promising therapeutic impacts | |
| 量化面肩肱型肌营养不良症的抗DUX4疗法 | Cowley, M. V. | N/A | Quantifying anti-DUX4 therapy for facioscapulohumeral muscular dystrophy | |
| 转录因子SlMYB41、SlMYB92和SlWRKY71调控番茄外皮层基因表达 | Jo, L. | N/A | Transcription factors SlMYB41, SlMYB92 and SlWRKY71 regulate gene expression in tomato exodermis | |
| 识别质膜孔蛋白在质膜孔中的存在 | Schladt, T. M. | N/A | Identification of nuclear pore proteins at plasmodesmata | |
| 在皮层和丘脑中，典型的突触和神经元特性的发育可以在没有小胶质细胞的情况下进行。 | O'Keeffe, M. | N/A | Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus | |
| 使用Exeter Multiscope自动测量心肌细胞单层收缩 | Corbett, A. D. | N/A | Automated measurement of cardiomyocyte monolayer contraction using the Exeter Multiscope | |
| 一种新型的小鼠前肢生物力学模型预测了在抓取运动的最优控制模拟中的肌肉活动 | Gilmer, J. I. | N/A | A novel biomechanical model of the mouse forelimb predicts muscle activity in optimal control simulations of reaching movements | |
| 脊髓V1中间神经元的转录组图谱揭示了En1在运动输出特定元素中的作用 | Trevisan, A. J. | N/A | The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output | |
| 在斑马鱼神经杆内局部光遗传激活NMYII会导致长距离、不对称的力量传播 | Crellin, H. A. | N/A | Local optogenetic NMYII activation within the zebrafish neural rod results in long-range, asymmetric force propagation | |
| SC-MAMBA2：利用状态空间模型实现高效的单细胞超长转录组建模 | Zhao, Y. | N/A | SC-MAMBA2: Leveraging State-Space Models for Efficient Single-Cell Ultra-Long Transcriptome Modeling | |
| 一项简单的措施减少了小鼠的高脂肪饮食摄入和肥胖 | Barrett, M. R. | N/A | A simple action reduces high fat diet intake and obesity in mice | |
| FIP 1.0数据集：高分辨率标注的4000个小麦地块在六年间的图像时间序列 | Roth, L. | N/A | The FIP 1.0 Data Set: Highly Resolved Annotated Image Time Series of 4,000 Wheat Plots Grown in Six Years | |
| 结合扩展显微技术和邻近标记技术揭示了锥虫核孔中保守且独特的非对称功能枢纽 | Gabiatti, B. P. | N/A | A combination of expansion microscopy and proximity labelling reveals conserved and unique asymmetric functional hubs at the trypanosome nuclear pore | |
| 从非靶向代谢组学数据中直接经验性地建立药物暴露记录 | Zhao, H. N. | N/A | Empirically establishing drug exposure records directly from untargeted metabolomics data | |
| 星形胶质细胞的区域特化是由出生后的发育过程塑造的。 | Schroeder, M. E. | N/A | Astrocyte regional specialization is shaped by postnatal development | |
| 气溶胶化合物对肺表面活性剂破坏作用的实验与建模 | Barlow, H. J. | N/A | Experiments and modelling of pulmonary surfactant disruption by aerosolised compounds | |
| B细胞表达的酶PexRAP（乙醚脂质生物合成中的中间体）促进了抗体反应和生发中心的大小。 | Cho, S. H. | N/A | B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size | |
| 比较系统性垂体腺苷酸环化酶激活肽（PACAP）和降钙素基因相关肽（CGRP）对小鼠运动诱导的恶心及平衡行为的影响 | Rahman, S. M. | N/A | Comparing The Impact of Systemic Pituitary Adenylate-Cyclase-Activating Polypeptide (PACAP) and Calcitonin Gene-Related Peptide (CGRP) on Motion-Induced Nausea And Balance Behaviors In Mice | |
| Bur1驱动的G1-到S期转变诱导了酵母检查点突变体对羟基脲的敏感性 | da Silva, S. C. R. | N/A | Bur1-driven G1-to-S phase transition induces hydroxyurea sensitivity in yeast checkpoint mutants | |
| 周期蛋白-G相关激酶（GAK）是一种新型的有丝分裂激酶，也是弥漫性大B细胞淋巴瘤的治疗靶点。 | Lightfuss, O. B. | N/A | The cyclin-G associated kinase (GAK) is a novel mitotic kinase and therapeutic target in diffuse large B-cell lymphoma | |
| 通过完整组装揭示了小鼠亚种间端粒和着丝粒的结构多样性 | Francis, B. | N/A | The structural diversity of telomeres and centromeres across mouse subspecies revealed by complete assemblies | |
| 精神分裂症和健康个体中持续存在的深层脑部形态和不对称性的性别差异：ENIGMA-精神分裂症工作组的元分析 | Cimmino, D. B. | N/A | Sex differences in deep brain shape and asymmetry persist across schizophrenia and healthy individuals: A meta-analysis from the ENIGMA-Schizophrenia Working Group | |
| CRB2耗竭诱导YAP信号传导并破坏足细胞的机械感应 | Sun, Y. | N/A | CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes | |
| 贫血和组织缺氧是疟疾低乳酸血症的主要决定因素。 | Georgiadou, A. | N/A | Anemia and tissue hypoxia are major determinants of malarial hypelactatemia | |
| 仿生光纳米生物界面实现了多尺度生物调控 | Mueller, C. | N/A | Biomimic opto-nanobiointerface enables multiscale biomodulation | |
| 用于检测纳米孔直接RNA测序中嵌合体伪影的基因组语言模型 | Li, Y. | N/A | A Genomic Language Model for Chimera Artifact Detection in Nanopore Direct RNA Sequencing | |
| 停留时间对视觉和被动引入运动情境效果的影响 | Alvarez-Hidalgo, L. | N/A | The impact of dwell time on the contextual effect of visual and passive lead-in movements | |
| 由光栅响应构建的编码流形在皮质视觉区域中组织了对自然场景的响应 | Dyballa, L. | N/A | Encoding manifolds constructed from grating responses organize responses to natural scenes in cortical visual areas | |
| 阿尔茨海默病进展过程中情景记忆网络的功能障碍 | Lattmann-Grefe, R. | N/A | Dysfunction of the episodic memory network in the Alzheimer's disease cascade | |
| 普通狨猴的拉绳行为 | Bertrand, M. | N/A | String-pulling by the common marmoset | |
| 抑制RNA调节因子HuR可有效缓解脊髓损伤，通过强力抑制损伤后的神经炎症。 | Husain, M. A. | N/A | Inhibition of the RNA Regulator HuR mitigates spinal cord injury by potently suppressing post-injury neuroinflammation | |
| 避孕药和激素相关功能连接组在月经周期中的特异性和普遍性 | Bottenhorn, K. L. | N/A | Idiosyncrasy and generalizability of contraceptive- and hormone-related functional connectomes across the menstrual cycle | |
| 共享和独特的终身压力源特征以及大脑网络预测青少年焦虑和抑郁 | Qu, Y. | N/A | Shared and unique lifetime stressor characteristics and brain networks predict adolescent anxiety and depression | |
| 结合组织病理学和机器学习的人工智能网络能够提取自闭症谱系障碍中的轴突病理。 | Yazdanbakhsh, A. | N/A | Artificial intelligence networks combining histopathology and machine learning can extract axon pathology in autism spectrum disorder | |
| 一种三维免疫标记方法，结合了过氧化物酶融合的纳米抗体和荧光素标记的酪胺-葡萄糖氧化酶信号放大技术 | Yamauchi, K. | N/A | A Three Dimensional Immunolabeling Method with Peroxidase-fused Nanobodies and Fluorochromized Tyramide-Glucose Oxidase Signal Amplification | |
| 解码嗅球输出：行为评估速率、同步性和呼吸相位编码 | Fu, X. | N/A | Decoding Olfactory Bulb Output: A Behavioral Assessment of Rate, Synchrony, and Respiratory Phase Coding | |
| 一种新型基于菁染料的荧光染料用于神经毒性条件下和体内脑研究的靶向线粒体成像 | Bi, L. | N/A | A Novel Cyanine-Based Fluorescent Dye for Targeted Mitochondrial Imaging in Neurotoxic Conditions and In Vivo Brain Studies | |
| 顶叶后皮质介导由稀有性引发的决策偏差及在不确定性下的学习过程。 | Sheng, W. | N/A | Posterior parietal cortex mediates rarity-induced decision bias and learning under uncertainty | |
| 早期对体液稳态的干扰会改变下丘脑摄食回路的发育，并导致摄食行为的特定情境变化。 | Sweet, S. R. | N/A | Early perturbations to fluid homeostasis alter development of hypothalamic feeding circuits with context-specific changes in ingestive behavior | |
| EEG-VLM工具箱：将体素化病变映射扩展至多维脑电数据 | Hardstone, R. | N/A | EEG-VLM Toolbox: Extending voxel-based lesion mapping to multi-dimensional EEG data | |
| UBR4、LRP1 和 OPHN1 在难治性癫痫中的相互作用：利用果蝇模型研究癫痫的多基因效应 | Huang, R.-N. | N/A | The Interaction of UBR4, LRP1, and OPHN1 in Refractory Epilepsy: Drosophila Model to Investigate the Oligogenic Effect on Epilepsy | |
| 产卵抑制神经元是果蝇大脑中多电路整合的潜在枢纽 | Weber Langstaff, R. | N/A | The Oviposition Inhibitory Neuron is a potential hub of multi-circuit integration in the Drosophila brain | |
| 摩擦系数之外的选择：精细触觉感知依赖于摩擦不稳定性 | Derkaloustian, M. | N/A | Alternatives to Friction Coefficient: Fine Touch Perception Relies on Frictional Instabilities | |
| 高精度神经反馈引导的冥想训练优化了现实世界中自我引导的冥想实践，以促进福祉。 | Ganesan, S. | N/A | High-precision neurofeedback-guided meditation training optimises real-world self-guided meditation practice for well-being | |
| 在个人空间中的多感官整合可以反映睡眠和意识障碍中的意识状态 | Bertoni, T. | N/A | Multisensory integration in Peripersonal Space indexes consciousness states in sleep and disorders of consciousness | |
| 显式获取的心理模式间相互关系降低认知负荷并促进小鼠和人工神经网络中新颖反应的出现。 | Singh, V. P. | N/A | Explicitly Acquired Interrelations Among Mental Schema Reduces Cognitive Load and Facilitates Emergence of Novel Responses in Mice and Artificial Neural Networks. | |
| 青春期C57BL/6J小鼠在单次暴饮乙醇暴露后情境消退学习的性别差异 | Cardona-Jordan, K. M. | N/A | Sex Differences in Contextual Extinction Learning After Single Binge-Like EtOH Exposure in Adolescent C57BL/6J Mice | |
| 在青光眼小鼠模型中，小胶质细胞对眼内压升高和视觉丘脑突触丢失做出反应。 | Thompson, J. L. | N/A | Microglia respond to elevated intraocular pressure and synapse loss in the visual thalamus in a mouse model of glaucoma. | |
| 连接蛋白43介导的线粒体转移可预防顺铂诱导的感觉神经退行性变。 | Owen, B. | N/A | Connexin 43 mediated mitochondrial transfer prevents cisplatin induced sensory neurodegeneration. | |
| “迷你分析”是突触变化的不可靠报道者 | Greger, I. H. | N/A | 'Mini analysis' is an unreliable reporter of synaptic changes | |
| 使用-SynVesT-1-成像技术研究衰老和阿尔茨海默病中的突触密度 | Giorgio, J. | N/A | Imaging synaptic density in ageing and Alzheimer's Disease with -SynVesT-1 | |
| 测试测试：利用基于连接组学的预测模型揭示标准化测试和临床症状所反映的系统 | Samardzija, A. | N/A | Testing the Tests: Using Connectome-Based Predictive Models to Reveal the Systems Standardized Tests and Clinical Symptoms Are Reflecting | |
| 在原条延伸期间及之后，中线模式对有丝分裂的敏感性存在差异 | Zhao, Z. | N/A | Differential Sensitivity of Midline Patterning to Mitosis during and after Primitive Streak Extension | |
| 小鼠跟腱成熟过程中的单核转录组和染色质可及性分析揭示了腱干细胞/祖细胞的分子图谱 | Asahara, H. | N/A | Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells | |
| 果蝇Trus，哺乳动物PDCD2L的直系同源基因，对于正常的细胞增殖、幼虫发育时序以及卵子发生是必需的。 | Takada, S. | N/A | Drosophila Trus, the orthologue of mammalian PDCD2L, is required for proper cell proliferation, larval developmental timing, and oogenesis | |
| 涡虫在反复接触电离辐射后发展出辐射耐受性 | Barghouth, P. G. | N/A | Planarians Develop Radiotolerance to Recurrent Ionizing Radiation Exposure | |
| Abl激酶通过调节FGF信号传导，独立于Crk磷酸化，以防止彼得氏异常。 | Wu, H. | N/A | Abl kinases regulate FGF signaling independent of Crk phosphorylation to prevent Peters anomaly | |
| Irx3/5 定义了耳蜗的感觉域，并调节哺乳动物内耳的前庭和耳蜗感觉模式。 | Liu, Y. | N/A | Irx3/5 define the cochlear sensory domain and regulate vestibular and cochlear sensory patterning in the mammalian inner ear | |
| 肺发育过程中初级纤毛和运动纤毛的时空动态变化 | Spurgin, S. | N/A | Spatiotemporal dynamics of primary and motile cilia throughout lung development | |
| 子宫基质而非上皮中的PTGS2对小鼠妊娠成功至关重要 | Massri, N. | N/A | Uterine stromal but not epithelial PTGS2 is critical for murine pregnancy success | |
| 塑造小鼠和沙鼠尾巴椎骨比例发育和进化的细胞和分子机制 | Weber, C. J. | N/A | Cellular and molecular mechanisms that shape the development and evolution of tail vertebral proportion in mice and jerboas | |
| 早期背侧胰腺芽中Hippo信号通路组分的表征 | Ahuja, N. H. | N/A | Characterization of Hippo Signaling Components in the Early Dorsal Pancreatic Bud | |
| IntelliProfiler：一种用于分析多个动物在家庭笼中行为动态的新型分析工具 | Ochi, S. | N/A | IntelliProfiler: a novel analytic tool for behavior dynamics of multiple animals in a home cage | |
| 背侧纹状体神经炎症通过破坏稳态星形胶质细胞功能导致过度目标导向行为控制 | Abiero, A. R. | N/A | Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting homeostatic astrocyte function | |
| 社会经验塑造了为繁殖成功而战的策略 | Gao, C. | N/A | Social Experience Shapes Fighting Strategies for Reproductive Success | |
| 持续整合航向和目标方向以引导转向 | Crown, A. M. | N/A | Continuous integration of heading and goal directions guides steering | |
| 在自然视觉过程中，人类视觉皮层早期的感觉反应最好由扫视（saccade）的开始，而非注视（fixation）的开始来解释。 | Amme, C. | N/A | Saccade onset, not fixation onset, best explains early sensory responses across the human visual cortex during naturalistic vision | |
| 身体游离揭示了思维的具身维度，具有独特的影响和神经特征。 | Banellis, L. | N/A | Body-wandering reveals an embodied dimension of thought with distinct affective and neural signatures | |
| 奖励激发等长握持动作 | Marbaker, R. M. | N/A | Reward invigorates isometric gripping actions | |
| 在模拟激活阈值时，统计方法考虑了神经元周围微观电场的畸变。 | Weise, K. | N/A | Statistical method accounts for microscopic electric field distortions around neurons when simulating activation thresholds | |
| 神经系统中降钙素基因相关受体成分蛋白（RCP）的缺失可偏向于gepant拮抗作用 | Rahman, S. | N/A | Loss of Calcitonin gene-related Related Receptor component protein (RCP) in nervous system can bias gepant antagonism | |
| 使用指数梯度进行类脑学习 | Cornford, J. | N/A | Brain-like learning with exponentiated gradients | |
| 第三人称视角冥想调节了最小自我和心跳引发的电位 | Yang, H. | N/A | Meditation in the third-person perspective modulates minimal self and heartbeat-evoked potentials | |
| 慢性激活皮质脊髓束神经元在锥体束切断术后既不能增强行为恢复，也不能促进轴突萌发。 | Wang, Z. | N/A | Chronic activation of corticospinal tract neurons after pyramidotomy injury enhances neither behavioral recovery nor axonal sprouting | |
| Ybx1引导C/EBPα和cBAF染色质重塑复合物，促进脂肪变性肝细胞中的脂肪生成基因表达。 | Jordan, J. M. | N/A | Ybx1 guides C/EBPα and cBAF chromatin-remodeling complex to promote adipogenic gene expression in steatotic hepatocytes | |
| 单核细胞衍生的CXCL12引导斑马鱼血管的定向迁移 | Liu, D. | N/A | Monocytes-derived cxcl12 guides a directional migration of blood vessels in zebrafish | |
| 定量解析秀丽隐杆线虫早期胚胎发育中的细胞命运 | Xiong, R. | N/A | Quantitative Resolving Cell Fate in the Early Embryogenesis of Caenorhabditis elegans | |
| 三刺鱼通过面部识别来识别熟悉的个体。 | SOGAWA, S. | N/A | Three-spined sticklebacks recognise familiar individuals by facial recognition | |
| 静息态功能连接在音频触觉语音训练后的变化 | Ciesla, K. | N/A | Resting-state functional connectivity changes following audio-tactile speech training | |
| 外显的视觉注意在腹侧和背侧内侧前额叶皮层中调节与决策相关的信号 | Shevlin, B. R. K. | N/A | Overt visual attention modulates decision-related signals in ventral and dorsal medial prefrontal cortex | |
| Gb3三糖基化外泌体作为志贺毒素1型的新型中和剂 | Mikolajczyk, K. | N/A | Gb3 trisaccharide-bearing exosomes as a novel neutralizer for Shiga toxin type 1 | |
| 原核生物和噬菌体中抗病毒防御系统的基因组景观 | Li, J. | N/A | Genomic landscape of antiviral defense systems in prokaryotes and phages | |
| 胚胎氧水平的变化提示了肢体起始的异时性。 | Zhu, M. | N/A | Shifts in embryonic oxygen levels cue heterochrony in limb initiation | |
| 空间定量代谢组学能够识别中风后对侧皮质代谢重编程的远距离和持续性 | Wang, G. | N/A | Spatial quantitative metabolomics enables identification of remote and sustained ipsilateral cortical metabolic reprogramming after stroke | |
| 拟南芥中鼠李半乳糖醛酸聚糖-I（RG-I）的深层结构分析揭示了果胶多样性的新见解 | Zhang, L. | N/A | Deep structural analysis of rhamnogalacturonan-I (RG-I) in Arabidopsis reveals new insights into pectin diversity | |
| UBA5抑制剂的鉴定与表征 | Singh, V. | N/A | Identification and characterization of UBA5 inhibitors | |
| 合理设计的鼻腔微生物群落体外代谢相互作用网络 | Bonillo-Lopez, L. | N/A | In vitro metabolic interaction network of a rationally designed nasal microbiota community | |
| Malat1通过控制早期分化和对IL2的反应来调节女性Th2细胞的细胞因子表达。 | Gwynne, M. | N/A | Malat1 regulates female Th2 cell cytokine expression through controlling early differentiation and response to IL2 | |
| 生物相互作用塑造了拟南芥中的感染结果 | Mahmoudi, M. | N/A | Biotic interactions shape infection outcomes in Arabidopsis | |
| 混合物中噬菌体的生命史特征决定了共感染的动态和效力 | Khan, R. | N/A | The life history traits of phages in a cocktail determine coinfection dynamics and efficacy | |
| 三种CRISPR-Cas类型之间的交叉对话使李斯特菌seeligeri中的引发型VI-A适应成为可能 | Margolis, S. R. | N/A | Crosstalk between three CRISPR-Cas types enables primed type VI-A adaptation in Listeria seeligeri | |
| 表达胸苷激酶的黄热病17D报告病毒有助于前药激活和感染细胞的生物正交标记 | Yakass, M. B. | N/A | Thymidine kinase-expressing yellow fever 17D reporter virus facilitates prodrug activation and bioorthogonal labelling of infected cells | |
| 由tafazzin控制的线粒体心磷脂代谢能够促进铁死亡 | Wohlfarter, Y. | N/A | Mitochondrial cardiolipin metabolism controlled by tafazzin enables ferroptosis | |
| 探索南大洋渔业变化机制：基于合作生产网络模型 | Ward, D. | N/A | Exploring mechanisms of change in a Southern Ocean fishery with a co-produced network model | |
| 长期变暖会颠倒生态系统功能与微生物资源获取之间的关系。 | Shinfuku, M. S. | N/A | Long-term warming inverts the relationship between ecosystem function and microbial resource acquisition | |
| 海藻全生物的季节性循环：多年时间序列揭示了重复的微生物变化和核心类群 | Mudlaff, C. M. | N/A | Seasonal cycles in a seaweed holobiont: A multiyear time series reveals repetitive microbial shifts and core taxa | |
| 揭示不同人类免疫细胞中转座元件介导的调控景观 | Du, C. | N/A | Unraveling transposable element-mediated regulatory landscape in diverse human immune cells | |
| 携带III型分泌系统2（T3SS2）和副溶血性弧菌TDH毒素的米氏弧菌在整合接合元件背景下的研究 | Morgado, S. | N/A | Vibrio mimicus carrying the Type III Secretion System 2 (T3SS2) and TDH toxin of Vibrio parahaemolyticus in an integrative conjugative element context | |
| 肾缺血-再灌注损伤后细胞状态和选择性剪接的动态变化 | Markiewitz, D. | N/A | Dynamics of cell states and alternative splicing following kidney ischemia-reperfusion injury | |
| 弧菌超整合子中ST热稳定肠毒素基因盒的表达模式 | Fonseca, E. L. | N/A | Expression pattern of the ST heat-stable enterotoxin gene cassettes in Vibrios superintegrons | |
| 一种序列特异性的RNA乙酰化催化剂 | Thalalla Gamage, S. | N/A | A sequence-specific RNA acetylation catalyst | |
| 表达人α1,4-半乳糖基转移酶的B4GALT5缺陷CHO-Lec2细胞：用于研究志贺毒素受体的糖工程细胞模型 | Mikolajczyk, K. | N/A | B4GALT5-deficient CHO-Lec2 cells expressing human alpha1,4-galactosyltransferase: a glycoengineered cell model for studying Shiga toxin receptors | |
| 人类MUTYH的结构及其癌症相关变体的功能分析揭示了其辅因子簇与活性位点之间的变构网络，这对DNA修复至关重要。 | Trasvina-Arenas, C. H. | N/A | Structure of human MUTYH and functional profiling of cancer-associated variants reveal an allosteric network between its cluster cofactor and active site required for DNA repair | |
| AlphaBridge：用于分析预测的大分子复合物的工具 | Alvarez Salmoral, D. | N/A | AlphaBridge: tools for the analysis of predicted macromolecular complexes | |
| 通过流形再现分析进行生成模型的验证 | Lazzaro, N. | N/A | Generative Models Validation via Manifold Recapitulation Analysis | |
| 在生理培养条件下以代谢为导向的化合物筛选发现了一种对未接受治疗和耐药黑色素瘤细胞具有高度抑制作用的NAMPT抑制剂。 | Preis, J. R. | N/A | Metabolism-oriented compound screen in physiological culture conditions identifies a NAMPT inhibitor highly effective against drug-naive and -resistant melanoma cells | |
| 确定同时抑制核黄素代谢和MEK作为胰腺癌的新型治疗策略 | Ooshio, T. | N/A | Identifying simultaneous inhibition of riboflavin metabolism and MEK as a novel therapeutic strategy for pancreatic cancer | |
| 精氨酸代谢的免疫原性转变触发了全身代谢和免疫系统的重新编程，以预防HER2阳性乳腺癌 | Sharma, V. | N/A | Immunogenic shift of arginine metabolism triggers systemic metabolic and immunological reprogramming to prevent HER2+ breast cancer | |
| 计算机预测和基因分析揭示了视黄酸调节作为遗传多样性秀丽隐杆线虫中保守的长寿通路的驱动因素 | Banse, S. A. | N/A | Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes | |
| 将DNA甲基化图谱与大鼠群中由β-肾上腺素能刺激引起的心脏病理联系起来 | Lahue, C. | N/A | Mapping DNA Methylation to Cardiac Pathologies Induced by Beta-Adrenergic Stimulation in a Large Panel of Mice | |
| FicD AMP化失调通过破坏胰腺内分泌稳态导致糖尿病 | Casey, A. K. | N/A | Dysregulation of FicD AMPylation causes diabetes by disrupting pancreatic endocrine homeostasis | |
| # BioRxiv 2024-10-25 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| ADP-核糖通过重塑嘌呤和嘧啶代谢触发神经元铁死亡 | Yuan, L. | N/A | ADP-ribose triggers neuronal ferroptosis by rewiring purine and pyrimidine metabolism | |
| 去泛素化抑制剂与SARS-CoV-2木瓜样蛋白酶结合的活性分析及其在鼠感染模型中的抗病毒功效 | Choudhary, S. | N/A | Activity profiling of deubiquitinating inhibitors-bound to SARS-CoV-2 papain like protease with antiviral efficacy in murine infection model | |
| 实验微生物群落中的宏观生态模式 | Shoemaker, W. R. | N/A | Macroecological patterns in experimental microbial communities | |
| 利用AlphaFold揭示hERG通道构象状态的秘密 | Ngo, K. | N/A | Harnessing AlphaFold to reveal hERG channel conformational state secrets | |
| JAK2/STAT3信号通路介导了甲基汞对小鼠星形胶质细胞神经元C8-D1A细胞系的毒性作用 | Ahmed, A. | N/A | JAK2/STAT3 signaling pathway mediates methylmercury toxicity in mouse astrocyte neuronal C8-D1A cell line | |
| 皮质醇动态变化及斑马鱼幼体在反复应激下依赖于糖皮质激素受体（GR）的反馈调节 | Castillo-Ramirez, L. A. | N/A | Cortisol dynamics and GR-dependent feedback regulation in zebrafish larvae exposed to repeated stress | |
| 早期生活挑战增强了斑马鱼幼体的皮质醇调节能力 | Castillo-Ramirez, L. A. | N/A | Early life challenge enhances cortisol regulation in zebrafish larvae | |
| 自扩增与环状mRNA疫苗在SARS-CoV-2免疫原性与保护效力方面的比较 | Singh, O. N. | N/A | Comparison of immunogenicity and protection efficacy of self-amplifying and circular mRNA vaccines for SARS-CoV-2 | |
| 肩胛间棕色脂肪组织的交感神经支配并不是雄性饮食诱导肥胖大鼠中OT引发体重增加和脂肪减少的主要介质。 | Edwards, M. M. | N/A | Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats | |
| EFP分析器：一款快速、准确且易于教学的程序，用于分析由诱导多能干细胞衍生的心肌细胞产生的胞外场电位 | Patel, N. P. | N/A | EFP Analyzer: A fast, accurate, and easy-to-teach program for analyzing Extracellular Field Potentials from iPSC-derived cardiomyocytes | |
| 季节性到年代际叶面积动态的通用模型 | Zhou, B. | N/A | A general model for the seasonal to decadal dynamics of leaf area | |
| 全球鉴定衣藻中AGO3-RNA相互作用揭示了小RNA介导的核与叶绿体基因表达调控 | Murakami, S. | N/A | Global identification of AGO3-RNA interactions in Chlamydomonas reveals the small RNA-mediated regulation of nuclear and chloroplast gene expression | |
| 利用明场显微镜进行虚拟染色，实现植物细胞结构的无标记定量分析 | Ichita, M. | N/A | Virtual staining from bright-field microscopy for label-free quantitative analysis of plant cell structures | |
| 两种物种和两种核型？西番莲属植物（Passifloraceae）中西番莲（Passiflora foetida L.）与西番莲（P. vesicaria L.）之间的细胞遗传分化 | Zirpoli, B. | N/A | Two species and two karyotypes? Cytogenetic differentiation between Passiflora foetida L. and P. vesicaria L. (Passifloraceae) | |
| CRISPR敲除偏向冬季的SUT4基因改变了田间种植杂交杨树的物候、生物量积累和繁殖能力。 | Tuma, T. T. | N/A | CRISPR knockout of winter-biased SUT4 alters phenology, biomass accrual, and fertility of field-grown hybrid poplar | |
| 苜蓿（Medicago truncatula）中的LYR4胞内域在免疫信号传导中充当支架，与其磷酸化活性无关。 | Simonsen, B. | N/A | The Medicago truncatula LYR4 intracellular domain serves as a scaffold in immunity signaling independent of its phosphorylation activity | |
| 印度次喜马拉雅地区传统作物的生物文化脆弱性 | Jaggi, H. | N/A | Biocultural vulnerability of traditional crops in the Indian Trans Himalaya | |
| 生长素-水杨酸跷跷板调节植物生长与食草动物防御之间的年龄依赖性平衡 | Han, W.-H. | N/A | Auxin-salicylic acid seesaw regulates the age-dependent balance between plant growth and herbivore defense | |
| 在马达加斯加的自然短日照和低肥力条件下，qHd7.1数量性状位点上的DJ123等位基因促进了早熟，且不影响产量。 | Kondo, K. | N/A | A DJ123 allele at the heading date quantitative trait locus qHd7.1 promotes early heading without yield penalties under natural short-day and low fertility conditions in Madagascar | |
| 水力机械信号的统一框架：植物信号是否随流而动？ | Bacheva, V. | N/A | A unified framework for hydromechanical signaling: Do plant signals go with the flow? | |
| 使用单色X射线荧光分析法对植物组织中的定量轻元素（钠和钾）进行分析 | Kahlon, P. S. | N/A | Quantitative light element (sodium and potassium) profiling in plant tissues using monochromatic X-ray fluorescence analysis | |
| 核孔复合体在植物中充当pri-miRNA转录和加工的枢纽 | Gonzalo, L. | N/A | The Nuclear Pore Complex acts as a hub for pri-miRNA transcription and processing in plants | |
| 可溶性CD52免疫抑制的分子基础由N-连接和O-连接糖基与HMGB1 Box B的相互作用所定义。 | DeBono, N. J. | N/A | The molecular basis of immunosuppression by soluble CD52 is defined by interactions of N-linked and O-linked glycans with HMGB1 Box B | |
| 基底隧道调节透明质酸合酶中的底物特异性转换 | Zhu, K. | N/A | Substrate tunnel regulates substrate specificity switching in hyaluronan synthase | |
| CRB2耗竭诱导YAP信号传导并破坏足细胞的机械感应 | Sun, Y. | N/A | CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes | |
| Shaker钾离子通道电压门控及达伐吡啶结合的结构基础：闭合状态模型揭示 | Pinto-Anwandter, B. I. | N/A | Structural Basis for Voltage Gating and Dalfampridine Binding in the Shaker Potassium Channel Revealed by Closed-State Model | |
| 同步辐射扫描化石的自动分割 | During, M. A. D. | N/A | Automated segmentation of synchrotron-scanned fossils | |
| 大麦可能是根寄生杂草列当的潜在陷阱作物。 | Inoue, M. | N/A | Barley is a potential trap crop for root parasitic weeds broomrapes | |
| 根系重塑机制与耐盐权衡：HKT1、TMAC2和TIP2;2在拟南芥中的作用 | Alshareef, N. | N/A | Root Remodeling Mechanisms and Salt Tolerance Trade-Offs: The Roles of HKT1, TMAC2, and TIP2;2 in Arabidopsis | |
| 人抗体识别的流感H1和H3血凝素上的保守位点 | Maurer, D. P. | N/A | Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies | |
| 拓扑异构酶1活性的表观遗传调控揭示了癌症的脆弱性 | Lee, T. | N/A | Epigenetic control of Topoisomerase 1 activity presents a cancer vulnerability | |
| 实验生物化学家和其他分子科学家机器学习入门 | Vince, M. J. | N/A | Getting Started with Machine Learning for Experimental Biochemists and Other Molecular Scientists | |
| 使用天然质谱技术通过丙氨酸扫描定义膜蛋白-脂质相互作用位点 | Jayasekera, H. S. | N/A | Alanine Scanning to Define Membrane Protein-Lipid Interaction Sites Using Native Mass Spectrometry | |
| 通过激光诱导的Soret效应实现亚稳态相分离液滴生成及长时间DNA富集 | Kobayashi, M. | N/A | Metastable phase-separated droplet generation and long-time DNA enrichment by laser-induced Soret effect | |
| 一个用于罕见癌症靶点发现的框架 | Li, B. | N/A | A framework for target discovery in rare cancers | |
| 姜黄素和胡椒碱纳米颗粒调节前列腺癌中的类固醇生物合成 | Yakubu, J. | N/A | Nanoparticles with Curcumin and Piperine Modulate Steroid Biosynthesis in Prostate Cancer | |
| 杜氏栀子（Gardenia duerrii）（Gardenieae科：茜草科），一种来自印度的新物种，以及Gardenia resinifera Roth的重新定型 | K, R. K. | N/A | Gardenia duerrii (Gardenieae : Rubiaceae), a new species from India and Neotypification of Gardenia resinifera Roth | |
| 默认模式网络中经验的碎片化和多线程处理 | Yazin, F. | N/A | Fragmentation and Multithreading of Experience in the Default-Mode Network | |
| 在健康泰国人群中，通过威斯康星卡片分类测试测量的认知变异性的蛋白质组关联：一种机器学习方法 | Chen, C. | N/A | Proteomic associations with cognitive variability as measured by the Wisconsin Card Sorting Test in a healthy Thai population: A machine learning approach | |
| 将宿主状况预测因子整合到病毒排放的时空多尺度模型中 | Kramer, A. M. | N/A | Integrating predictors of host condition into spatiotemporal multi-scale models of virus shedding | |
| 致癌性改变、种族与接受体细胞肿瘤下一代测序的美国转移性前列腺癌退伍军人生存率的关系 | Valle, L. F. | N/A | Oncogenic Alterations, Race, and Survival in US Veterans with Metastatic Prostate Cancer Undergoing Somatic Tumor Next Generation Sequencing | |
| 生物医学数据的AI准备度：Bridge2AI建议 | Clark, T. | N/A | AI-readiness for Biomedical Data: Bridge2AI Recommendations | |
| 降低ETFDH表达可优化癌细胞的生物能量学 | Papadopoli, D. | N/A | Reduction in ETFDH expression optimizes cancer cell bioenergetics | |
| 一种自适应自回归扩散方法用于设计主动人源化抗体和纳米抗体 | Ma, J. | N/A | An adaptive autoregressive diffusion approach to design active humanized antibody and nanobody | |
| 高效推理、训练与微调蛋白质语言模型 | Celik, M. H. | N/A | Efficient Inference, Training, and Fine-tuning of Protein Language Models | |
| 在癌症单细胞研究中，通过筛选去除高线粒体含量的细胞，可以有效清除那些代谢发生改变的恶性细胞群体，这些细胞群体在生物学上仍然具有活力。 | Yates, J. | N/A | Filtering cells with high mitochondrial content removes viable metabolically altered malignant cell populations in cancer single-cell studies | |
| scMoE：用于从异质性单细胞RNA测序数据中学习层次化、细胞类型特异性和可解释表示的单细胞专家混合模型 | Huang, M. | N/A | scMoE: single-cell mixture of experts for learning hierarchical, cell-type-specific, and interpretable representations from heterogeneous scRNA-seq data | |
| 致癌长链非编码RNA NEAT1和MALAT1在二维单层与三维肿瘤球体培养中的差异表达及其对癌症进展的意义 | Ghosh, A. | N/A | Differential expression of oncogenic lncRNAs NEAT1 and MALAT1 in 2D monolayer vs. 3D tumoroid culture and its implications in cancer progression | |
| Unc-51样激酶1（ULK1）调控细菌泛素化和p62招募在李斯特菌异噬清除过程中的作用 | Siqueira, M. S. | N/A | Unc-51-like Kinase 1 (ULK1) Regulates Bacterial Ubiquitylation and p62 Recruitment during Xenophagic Clearance of Listeria monocytogenes | |
| 甘蓝型油菜高温萌发适应性的未开发多样性 | Tiret, M. | N/A | An unexplored diversity for adaptation of germination to high temperatures in Brassica species | |
| 来自热河生物群的具冠白垩纪反鸟类中的虹彩结构色 | LI, Z. | N/A | Iridescent structural coloration in a crested Cretaceous enantiornithine bird from Jehol Biota | |
| 组装钌复合物形成钌体，释放铁蛋白吞噬介导的肿瘤抑制作用 | Meng, C. | N/A | Assembling Ruthenium Complexes to Form Ruthenosome Unleashing Ferritinophagy-mediated Tumor Suppression | |
| 半胱氨酸氧化对SARS-CoV-2刺突蛋白构象变化的影响：来自原子模拟的见解 | Ghasemitarei, M. | N/A | Effect of cysteine oxidation in SARS-CoV-2 Spike protein on its conformational changes: insights from atomistic simulations | |
| 血管生成和免疫预测因素在伴有静脉瘤栓的肾细胞癌中对新辅助阿昔替尼反应的影响 | Wray, R. | N/A | Angiogenic and Immune Predictors of Neoadjuvant Axitinib Response in Renal Cell Carcinoma with Venous Tumour Thrombus | |
| 染色体不稳定性通过细胞外囊泡中的EFEMP1促进细胞迁移和侵袭 | Foijer, F. | N/A | Chromosomal instability promotes cell migration and invasion via EFEMP1 in extracellular vesicles | |
| 脂联素受体激动剂可预防杜氏肌营养不良小鼠模型中的右心室组织病理学变化。 | Gandhi, S. | N/A | Adiponectin-receptor agonism prevents right ventricular tissue pathology in a mouse model of Duchenne muscular dystrophy | |
| TIR信号激活了细菌中的类似胱天蛋白酶的免疫反应。 | ROUSSET, F. | N/A | TIR signaling activates caspase-like immunity in bacteria | |
| 一项新的筛选检测揭示，氨基糖苷类抗生素干扰Tau/MDM2相互作用。 | Sola, M. | N/A | A new screening assay reveals that aminoglycoside antibiotics interfere with the Tau/MDM2 interaction | |
| 将IICR扩展到复杂的非平稳结构化模型 | Jouniaux, A. | N/A | Extending the IICR to complex non-stationary structured models | |
| 从geissoschizine出发的单萜吲哚生物碱的分歧生物合成 | Kamileen, M. O. | N/A | Divergent biosynthesis of monoterpene indole alkaloids from geissoschizine | |
| 替代性转录本通过重新编码人类基因，表达出重叠且发生移码的微型蛋白质。 | Su, H. | N/A | Alternative transcripts recode human genes to express overlapping, frameshifted microproteins | |
| 黄芩素通过下调新生儿Fc受体并通过NF-κB信号通路改善实验性溃疡性结肠炎的复发 | Hu, H. | N/A | Baicalein ameliorates experimental ulcerative colitis recurrency by downregulating neonatal Fc receptor via the NF-κB signaling pathway | |
| 从等位基因包含中学习抗体序列约束 | Jagota, M. | N/A | Learning antibody sequence constraints from allelic inclusion | |
| 纽芬兰与拉布拉多鳕鱼崩溃后的快速生态系统变化 | Wudrick, A. | N/A | Rapid ecosystem change after the cod collapse in Newfoundland & Labrador | |
| 何时信任表观遗传时钟：避免衰老干预中的假阳性。 | Borrus, D. S. | N/A | When to Trust Epigenetic Clocks: Avoiding False Positives in Aging Interventions. | |
| 对Batrachochytrium dendrobatidis GPL JEL423的近乎完整的端粒到端粒基因组组装揭示了CBM18基因家族的扩展和M36金属蛋白酶基因家族的收缩。 | Helmstetter, N. | N/A | A near-complete telomere-to-telomere genome assembly for Batrachochytrium dendrobatidis GPL JEL423 reveals a CBM18 gene family expansion and a M36 metalloprotease gene family contraction. | |
| 可转座元件小RNA和长RNA在老化大脑中的作用及其对亨廷顿病和帕金森病的启示 | Dayama, G. | N/A | Transposable element small and long RNAs in aging brains and implications in Huntington's and Parkinson's disease | |
| 全基因组变异分析揭示了埃及伊蚊及其形态变种埃及伊蚊var. luciensis之间不同的遗传特征。 | Gupta, B. | N/A | Genome-wide variant analysis reveals divergent genetic signatures in Aedes aegypti and its morphological variant Aedes aegypti var. luciensis | |
| WRI1在天然橡胶中多乳汁代谢途径整合调控中的普遍功能 | Fan, R. | N/A | Universal function of WRI1 involved in integrated regulation of multiple latex metabolism pathways in Natural Rubber | |
| 在黑色素瘤起始过程中，吸引子状态区域先于神经嵴命运出现。 | McConnell, A. M. | N/A | An attractor state zone precedes neural crest fate in melanoma initiation | |
| 线粒体靶向质体醌疗法改善了小鼠卵巢癌恶病质前期的早期肌肉无力症状 | Delfinis, L. J. | N/A | Mitochondrial-targeted plastoquinone therapy ameliorates early onset muscle weakness that precedes ovarian cancer cachexia in mice | |
| CXADR是一种人IgG Fc受体。 | Emig, C. J. | N/A | CXADR is a Human IgG Fc Receptor | |
| 不同的母胎免疫特征描绘了尿路感染后早产的发作 | Ottinger, S. | N/A | Distinct maternofetal immune signatures delineate preterm birth onset following urinary tract infection | |
| 在人类慢性基孔肯雅病毒性关节炎疾病中鉴定免疫原性和交叉反应的基孔肯雅病毒特异性CD4+ T细胞表位 | Agarwal, R. | N/A | Identification of immunogenic and cross-reactive chikungunya virus-specific CD4+ T cell epitopes in chronic chikungunya viral arthritic disease in humans | |
| 小鼠接种高效和低效全细胞百日咳疫苗后产生的抗体谱 | Adewunmi, Y. | N/A | Antibody Profiles Elicited by Potent and Subpotent Whole Cell Pertussis Vaccines in Mice | |
| 2,3,7,8-四氯二苯并-对-二噁英（TCDD）引发了与肝脏芳香烃受体（AHR）介导的差异基因表达相关的剂量依赖性小鼠尿液代谢组变化。 | Sink, W. J. | N/A | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) elicited dose-dependent shifts in the murine urinary metabolome associated with hepatic AHR-mediated differential gene expression | |
| 无花果蜂的基因组揭示了无花果-无花果蜂共生关系中的适应与共进化 | Lo, B.-W. | N/A | Genomes of Wiebesia fig wasps reveal the adaptation and codiversification in fig-fig wasp mutualism | |
| 通过空间脂质组学和蛋白质组学相关性进行异质性评估和蛋白质通路预测：推进用于人类胶质母细胞瘤预后的干蛋白质组学概念 | Lagache, L. | N/A | Heterogeneity Assessment and Protein Pathway Prediction via Spatial Lipidomic and Proteomic Correlation: Advancing Dry Proteomics concept for Human Glioblastoma Prognosis | |
| AMPK激活通过其去磷酸化促进TFEB的转录激活。 | Negoita, F. | N/A | AMPK activation promotes transcriptional activation of TFEB through its dephosphorylation | |
| 利用β-孔形成毒素Aerolysin增强单链纳米体对Notch的抑制及亲和力 | Lemmex, A. | N/A | Single-chain nanobody inhibition of Notch and avidity enhancement utilizing the β-pore forming toxin Aerolysin | |
| 利用时序卷积生成语言模型设计功能性酵母启动子序列 | Alsaggaf, I. | N/A | Functional yeast promoter sequence design using temporal convolutional generative language models | |
| 部分特征化的拓扑结构指导可靠的无锚点单细胞RNA整合 | He, C. | N/A | Partially characterized topology guides reliable anchor-free scRNA integration | |
| 膜联蛋白A6通过与三阴性乳腺癌细胞中的SNAP23相互作用，调节促炎细胞因子和外泌体的分泌。 | Sakwe, N. I. | N/A | Annexin A6 modulates the secretion of pro-inflammatory cytokines and exosomes via interaction with SNAP23 in triple negative breast cancer cells | |
| 钴原卟啉IX对小鼠粒细胞动员和代谢标志物的剂量和时间依赖性效应 | Bednarz, A. | N/A | Dose- and time-dependent effects of cobalt protoporphyrin IX on granulocyte mobilization and metabolic markers in mice | |
| 转录组分析揭示了幼年公牛鳟鱼亚致死热应激阈值的见解 | Best, C. | N/A | Transcriptional profiling provides insights on sublethal thermal stress thresholds in juvenile bull trout | |
| 线粒体靶向抗氧化剂SkQ1可预防与线粒体相关的细胞凋亡，但不能预防坏死性凋亡或卵巢癌中的骨骼肌萎缩。 | Khajehzadehshoushtar, S. | N/A | The mitochondrial-targeted antioxidant SkQ1 prevents mitochondrial-linked apoptosis but not necroptosis or skeletal muscle atrophy in ovarian cancer | |
| 利用iColonEpithelium代谢重建理解人类结肠上皮细胞中与疾病相关的代谢变化 | Jiang, B. | N/A | Understanding disease-associated metabolic changes in human colon epithelial cells using iColonEpithelium metabolic reconstruction | |
| 成虫饮食对昆虫Narnia femorata（半翅目：Coreidae科）的角质层厚度和抗损伤能力有显著影响。 | Greenway, E. V. | N/A | Adult diet strongly affects cuticle thickness and its injury resistance in the insect Narnia femorata (Hemiptera: Coreidae) | |
| 用于研究基因组组织与转录调控相互作用的计算机纳米显微镜 | Gopi, S. | N/A | In silico nanoscope to study the interplay of genome organization and transcription regulation | |
| 人类世鱼类食物网的退化 | Carvajal-Quintero, J. D. | N/A | Degradation of fish food webs in the anthropocene | |
| 合作最大化生物多样性 | Godoy, O. | N/A | Cooperation maximizes biodiversity | |
| 开发和验证用于eDNA监测和认证10种商业上重要的秘鲁海洋物种的多功能种特异性引物检测方法 | Marin, A. | N/A | Development and validation of versatile species-specific primer assays for eDNA monitoring and authentication of 10 commercially important Peruvian marine species | |
| 通过遗传免疫表型分析，探索冈比亚按蚊免疫细胞生物学的新维度 | Samantsidis, G.-R. | N/A | Exploring new dimensions of immune cell biology in Anopheles gambiae through genetic immunophenotyping | |
| 子宫内膜在着床窗口期细胞成分的变化与复发性流产相关。 | Reddin, I. G. | N/A | Changes in the cellular composition of the endometrium during the implantation window are associated with recurrent pregnancy loss | |
| 蕨类植物满江红（Azolla caroliniana）的基因组组装 | Song, M. J. | N/A | The genome assembly of the duckweed fern, Azolla caroliniana | |
| gp82结合的原子级洞察：对克鲁斯锥虫宿主细胞入侵的微秒级、百万原子探索 | Rosa, R. S. L. | N/A | Atomistic Insights into gp82 Binding: A Microsecond, Million-Atom Exploration of Trypanosoma cruzi Host-Cell Invasion | |
| 铜绿假单胞菌H16中利用H2生产木糖醇 | Jämsä, T. | N/A | H2-driven xylitol production in Cupriavidus necator H16 | |
| 解析蛋白质-碳水化合物界面的多样性：来自多尺度研究的见解 | Gheeraert, A. | N/A | Unraveling the diversity of protein-carbohydrate interfaces: insights from a multi-scale study | |
| 通过自动化计算流程HitList发现重要人畜和植物真菌病原体的新靶点 | Condon, D. E. | N/A | Discovery of Novel Targets for Important Human and Plant Fungal Pathogens via Automated Computational Pipeline HitList | |
| 通过碱基对基序能量进行RNA二级结构的深度可泛化预测 | Zhu, H. | N/A | Deep generalizable prediction of RNA secondary structure via base pair motif energy | |
| 长读长比对堆积的K-mer分析用于结构变异基因分型 | ENGLISH, A. C. | N/A | K-mer analysis of long-read alignment pileups for structural variant genotyping | |
| Metagenomics-Toolkit：灵活高效的云端宏基因组学工作流程，具备机器学习驱动的资源分配功能 | Belmann, P. | N/A | Metagenomics-Toolkit: The Flexible and Efficient Cloud-Based Metagenomics Workflow featuring Machine Learning-Enabled Resource Allocation | |
| 单个癌细胞中多种ecDNA类型的维持 | Scanu, E. | N/A | The maintenance of multiple ecDNA types in single cancer cells | |
| 利用ReSisTrace谱系追踪技术揭示急性髓系白血病中FLT3抑制剂的预敏化剂 | Eriksson, J. | N/A | Uncovering pre-sensitizing agents to FLT3 inhibitors in acute myeloid leukemia with ReSisTrace lineage tracing | |
| 单链DNA结合因子SUB1/PC4减轻端粒处的复制应激，是ALT癌细胞的脆弱点 | Dubois, J.-C. | N/A | The Single-Stranded DNA-Binding Factor SUB1/PC4 Alleviates Replication Stress at Telomeres and is a Vulnerability of ALT Cancer Cells | |
| IRE1依赖的GOLIM4表达控制蛋白质分泌以调节胶质母细胞瘤细胞的粘附和迁移 | Bakambamba, K. | N/A | IRE1-dependent GOLIM4 expression controls protein secretion to modulate glioblastoma cell adhesion and migration | |
| 综合结构-功能分析揭示了影响致癌KRAS活性的获得性和丧失性功能机制 | Kwon, J. | N/A | Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity | |
| 染色体外DNA驱动胶质母细胞瘤中的癌基因空间异质性与演化 | Noorani, I. | N/A | Extrachromosomal DNA driven oncogene spatial heterogeneity and evolution in glioblastoma | |
| 抑制调节性T细胞中的UBE2N可增强抗癌免疫力 | Miao, W. | N/A | Inhibition of UBE2N in regulatory T-cells boosts immunity against cancer | |
| 贫血和组织缺氧是疟疾低乳酸血症的主要决定因素。 | Georgiadou, A. | N/A | Anemia and tissue hypoxia are major determinants of malarial hypelactatemia | |
| 长链酰基辅酶A脱氢酶的丧失可预防急性肾损伤 | Chiba, T. | N/A | Loss of long-chain acyl-CoA dehydrogenase protects against acute kidney injury | |
| 由羟基醌形成驱动的CBD毒性 | Montero, M. I. | N/A | Cannabidiol Toxicity Driven by Hydroxyquinone Formation | |
| 新型链霉菌SCA4-21对香蕉枯萎病的生物防治效果及机制 | Qi, D. | N/A | Biocontrol efficiency and mechanism of novel Streptomyces luomodiensis SCA4-21 against banana Fusarium wilt | |
| SLB-msSIM：一种基于光谱库的多重分段SIM平台，用于单细胞蛋白质组学分析 | Senavirathna, L. | N/A | SLB-msSIM: a spectral library-based multiplex segmented SIM platform for single-cell proteomic analysis | |
| 机械感受器在响应微生物感染时启动先天免疫 | Stucchi, G. | N/A | Mechanoreceptors initiate innate immunity in response to microbial infections | |
| 生成人类诱导多能干细胞（iPSC）衍生的胰腺类器官，以研究胰腺发育和疾病 | Darrigrand, J.-F. | N/A | Generation of human iPSC-derived pancreatic organoids to study pancreas development and disease | |
| 无特质匹配：使用对应分析分析交互网络的潜在结构 | Nicvert, L. | N/A | Trait matching without traits: using correspondence analysis to analyze the latent structure of interaction networks | |
| 土地利用强度、生产力和地上丰富度对温带草地种子雨的影响 | Klinger, Y. P. | N/A | Impact of land-use intensity, productivity, and aboveground richness on seed rain in temperate grasslands | |
| 长链非编码RNA NEAT1和MALAT1的系统发育研究：推断结构-功能联系 | Arkhipova, K. | N/A | Phylogenetic Study of Long Non-Coding RNA NEAT1 and MALAT1 to Infer Structural-Functional Connection | |
| 入侵植物马缨丹（Lantana camara）的种群结构受其交配系统的影响。 | Praveen, P. | N/A | The population structure of invasive Lantana camara is shaped by its mating system | |
| PWWP-ADD和DNMT3B1的N端结构域赋予了对发育调控的CpG岛甲基化的特异性 | Yasmin, K. | N/A | PWWP-ADD and N-terminal domains of DNMT3B1 confer specificity for developmentally regulated CpG island methylation | |
| 有机光电纳米生物界面实现了多尺度生物调控 | Mueller, C. | N/A | Organic opto-nanobiointerface enables multiscale biomodulation | |
| 等分散泊松分布（Equi-Under-Dispersed Possion Distribution，简称EUPoisson） | Hassan, M. | N/A | Equi-Under-Dispersed Possion Distribution (EUPoisson) | |
| 智能数据工厂：面向主动学习驱动分子数据采集的志愿者计算平台 | Ghukasyan, T. | N/A | SMART DATA FACTORY: VOLUNTEER COMPUTING PLATFORM FOR ACTIVE LEARNING-DRIVEN MOLECULAR DATA ACQUISITION | |
| 一种高吞吐量的单分子平台，用于研究DNA超螺旋效应对蛋白质-DNA相互作用的影响 | Lee, H. | N/A | A high throughput single molecule platform to study DNA supercoiling effect on protein-DNA interactions | |
| 单核分析未折叠蛋白反应（SNUPR）：揭示多发性骨髓瘤中硼替佐米耐药机制的新方法 | Arguello, R. J. | N/A | Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma | |
| 使用区间分析设计满足稳态规格的生物分子电路参数区间 | Prakash, R. | N/A | Design of Parameter Intervals to Meet Steady-State Specifications in Biomolecular Circuits using Interval Analysis | |
| 洗牌：扩展合成生物学工具包以用于类似洗牌子的重组系统 | Katalinic, J. | N/A | Do the shuffle: Expanding the synthetic biology toolkit for shufflon-like recombination systems | |
| 多细胞比例-积分-微分控制对生物过程的鲁棒调节 | Martinelli, V. | N/A | Multicellular Proportional-Integral-Derivative Control for Robust Regulation of Biological Processes | |
| 太暗、太亮和刚刚好：适应光应激和限制下的莱茵衣藻昼夜节律程序的系统分析 | Dupuis, S. | N/A | Too dim, too bright, and just right: Systems analysis of the Chlamydomonas diurnal program upon acclimation to light stress and limitation | |
| 鞭毛运动和黏液环境影响铜绿假单胞菌在慢性肺部感染中的聚集介导的抗生素耐药性 | Higgs, M. G. | N/A | Flagellar motility and the mucus environment influence aggregation mediated antibiotic tolerance of Pseudomonas aeruginosa in chronic lung infection | |
| 利用分子生物学和微生物学相结合的方法，鉴定英国蚕豆根腐病相关的镰刀菌种类 | Attar, B. | N/A | Identifying the Fusarium species involved in foot rot disease of faba beans in the UK using a combined molecular and microbiological approach | |
| 基于营养的根际微生物群工程原理，通过活体微生物接种剂调控作物产量 | Huang, Y. | N/A | Principles of nutrition-dependent root-microbiome engineering for regulating crop yield via live microbial inoculants | |
| 抑制白假丝酵母毒力因子由维罗纳气单胞菌V03衍生的环二肽实现 | Sekar, J. | N/A | Inhibition of Candida albicans virulence factor by cyclic dipeptides derived from Aeromonas veronii V03 | |
| 增强抗菌药物耐药性监测：基于牛津纳米孔测序技术（ONT）的核心质粒多位点序列分型（cpMLST） | Xavier, B. B. | N/A | Enhancing antimicrobial resistance monitoring: Core Plasmid Multi-Locus sequence typing (cpMLST) with Oxford Nanopore sequencing technology (ONT) | |
| 理解结核分枝杆菌的流行病学和发病机制，结合非冗余泛基因组和群体遗传学 | Zhou, Y. | N/A | Understanding the epidemiology and pathogenesis of Mycobacterium tuberculosis with non-redundant pangenome and population genetics | |
| 碳青霉烯耐药肺炎克雷伯菌的临床特征、耐药基因及毒力分析 | He, J. | N/A | Clinical characteristics, drug-resistance genes and virulence analysis of carbapenem-resistant Klebsiella pneumoniae | |
| 基于RNA toehold开关的报告分析法用于评估细菌对反义寡核苷酸的摄取 | Sarkar, P. | N/A | RNA toehold switch-based reporter assay to assess bacterial uptake of antisense oligomers | |
| 关键刺突蛋白突变的流行及其对孟加拉国锡尔赫特市COVID-19临床表现影响有限 | Akter, S. | N/A | Prevalence of Key Spike Protein Mutations and Their Limited Effect on COVID-19 Clinical Manifestations in Sylhet, Bangladesh | |
| 长期免疫效果：经伽马射线照射的SARS-CoV-2 S1蛋白亚单位疫苗微针阵列贴片在小鼠中的研究 | Kim, E. | N/A | Long-term Immunity of a Microneedle Array Patch of SARS-CoV-2 S1 Protein Subunit Vaccine Irradiated by Gamma Rays in Mice | |
| FBXW7通过减轻c-MYC对丙酮酸羧化酶的抑制作用，支持代谢灵活性。 | Lisci, M. | N/A | FBXW7 alleviates c-MYC repression of pyruvate carboxylase to support metabolic flexibility | |
| 探究DNA损伤位点揭示了依赖于上下文和新的DNA损伤反应因子 | Cardoso da Silva, R. | N/A | Probing DNA damage sites reveals context-dependent and novel DNA damage response factors | |
| 依赖于序列的跨膜转运蛋白介导的膜界面螺旋插入的尺度 | Grau, B. | N/A | Sequence-dependent scale for translocon-mediated insertion of interfacial helices in membranes | |
| 抑制衰老的载脂蛋白E4小鼠体内的胆固醇储存酶ACAT1/SOAT1，改变了它们大脑的炎症特征。 | Huynh, T. N. | N/A | Inhibiting the cholesterol storage enzyme ACAT1/SOAT1 in aging Apolipoprotein E4 mice alter their brains inflammatory profiles | |
| 水热处理酵母细胞壁在单独条件下抑制MCF7细胞的生长。 | KITAGAWA, T. | N/A | Hydrothermally treated yeast cell wall suppresses the growth of MCF7 cells under isolated conditions. | |
| 进化尺度酶学使我们能够在多峰催化景观中预测生化常数 | Muir, D. F. | N/A | Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape | |
| 利用数据不平衡性来增强化合物-蛋白质相互作用预测模型 | Lin, W. | N/A | Utilizing data imbalance to enhance compound-protein interaction prediction models | |
| 离子迁移谱引导的分子鉴别：脂质组学实验中区分缩醛磷脂与其他醚脂的方法 | Koch, J. | N/A | Trapped ion mobility spectrometry-guided molecular discrimination between plasmalogens and other ether lipids in lipidomics experiments | |
| 唾液代谢组分的构成与SARS-CoV2感染及COVID-19疾病的严重程度显著相关。 | Larios-Serrato, V. | N/A | Composition of saliva metabolome is significantly associated with SARS-CoV2 infection and with severity of COVID-19 disease | |
| 使用合成RNA评估直接RNA测序中的多腺苷酸尾长度推断。 | Chang, J. J.-Y. | N/A | Using synthetic RNA to benchmark poly(A) length inference from direct RNA sequencing. | |
| 孟加拉国禽类样本中分离出的细菌中的重金属与抗生素共耐药性：一种新兴的环境威胁 | Sarker, A. | N/A | Heavy Metal and Antibiotic Co-resistance in Bacteria Isolated from Poultry Samples in Bangladesh: An Emerging Environmental Threat | |
| 肺和肠道微生物群对SARS-CoV-2感染的不同反应：武汉株与Omicron株在K18-hACE2转基因小鼠中的比较研究 | Kim, C. W. | N/A | Differential Responses of Lung and Intestinal Microbiota to SARS-CoV-2 Infection: A Comparative Study of the Wuhan and Omicron Strains in K18-hACE2 tg Mice | |
| 大麦miRNAs及其靶标在发育早期对热胁迫的响应调控 | Kruszka, K. | N/A | Barley miRNAs and their targets regulation in response to heat stress at the early stage of development | |
| 综合系统生物学研究表明，线粒体功能和代谢的紊乱是导致保留射血分数的心力衰竭（HFpEF）的关键因素。 | Gibb, A. A. | N/A | Integrated systems biology identifies disruptions in mitochondrial function and metabolism as key contributors to heart failure with preserved ejection fraction (HFpEF) | |
| HT SpaceM：一种高通量且可重复的小分子单细胞代谢组学方法 | Delafiori, J. | N/A | HT SpaceM: A High-Throughput and Reproducible Method for Small-Molecule Single-Cell Metabolomics | |
| β-淀粉样蛋白损害蛋白酶体结构和功能。蛋白酶体激活可减轻淀粉样蛋白引起的毒性和认知缺陷。 | Davidson, K. | N/A | β-Amyloid impairs Proteasome structure and function. Proteasome activation mitigates amyloid induced toxicity and cognitive deficits | |
| 使用多重竞争性等位基因特异性PCR（mxKASP）基因分型确定合子性 | de Visser, M. C. | N/A | Determining zygosity with multiplex Kompetitive Allele-Specific PCR (mxKASP) genotyping | |
| 在碱基切除修复途径的下游步骤中，LIG1和LIG3α在8-oxoG旁路过程中对polβ错配插入产物进行诱变连接 | Lee, K. M. | N/A | Mutagenic ligation of polβ mismatch insertion products during 8-oxoG bypass by LIG1 and LIG3α at the downstream steps of base excision repair pathway | |
| 对倍半萜香豆素合酶反应机制的预测表明其与三萜生物合成存在直接的进化联系。 | Stephenson, M. J. | N/A | Prediction of the reaction mechanisms of sesquiterpene coumarin synthases supports a direct evolutionary link with triterpene biosynthesis. | |
| ProteinWeaver：一个用于可视化本体注释蛋白质网络的网络工具 | Anderson, O. | N/A | ProteinWeaver: A Webtool to Visualize Ontology-Annotated Protein Networks | |
| 在感染沃尔巴克氏菌株wAlbB的埃及伊蚊孟加拉国品系中，适应性与登革病毒抑制的关系 | Al-Amin, H. M. | N/A | Fitness compatibility and dengue virus inhibition in a Bangladeshi strain of Aedes aegypti infected with the Wolbachia strain wAlbB | |
| 以微外显子下游剪接供体位点为靶点的寡核苷酸：自闭症创新疗法 | Martinez-Pizarro, A. | N/A | OLIGONUCLEOTIDES TARGETING THE SPLICE ACCEPTOR SITE DOWNSTREAM OF A MICROEXON AS AN INNOVATIVE THERAPY FOR AUTISM | |
| 实验田试验模型展示了气候危机将如何改变Vitis sp. L'Acadie Blanc叶片微环境和果实微环境的真菌群落。 | Blakney, A. J. C. | N/A | Experimental field trials model how the climate crisis will alter the phyllosphere and carposphere fungal communities of Vitis sp. L'Acadie Blanc | |
| 贾第虫晚期ESCRT组分的不同功能：基于亚细胞分布和蛋白质相互作用的见解 | Patra, N. | N/A | Divergent Functions of Late ESCRT Components in Giardia lamblia: Insights from Subcellular Distributions and Protein Interactions | |
| 象牙喙啄木鸟与蓝松鸦在频谱图层面的对比显示出差异 | Williams, J. D. | N/A | Ivory-billed Woodpecker and Blue Jay kent comparisons at spectrogram level reveal differences | |
| 保守的基因内容和独特的系统发育历史特征了“bloopergene”，这是Triturus平衡致死系统的基础。 | de Visser, M. C. | N/A | Conserved gene content and unique phylogenetic history characterize the 'bloopergene' underlying Triturus' balanced lethal system | |
| 丝状真菌核基因组中的Zymocin样杀伤毒素基因簇 | Heneghan, P. G. | N/A | Zymocin-like killer toxin gene clusters in the nuclear genomes of filamentous fungi | |
| 没有其微生物组的果蝇的实验进化 | Malwade, A. | N/A | Experimental evolution of Drosophila without its microbiome | |
| 父系基因组消除、单基因复制和非典型性染色体系统的进化遗传学 | Hitchcock, T. J. | N/A | Paternal genome elimination, monogenic reproduction, and the evolutionary genetics of atypical sex chromosome systems | |
| 信号调节结构如何演变：来自进化模型的见解 | Asgari, D. | N/A | How the Structure of Signaling Regulation Evolves: Insights from an Evolutionary Model | |
| MIRAGE：一种结合变异功能信息的贝叶斯稀有变异关联分析方法 | Han, S. | N/A | MIRAGE: a Bayesian rare variant association analysis method incorporating functional information of variants | |
| Mettl5协调蛋白质的生成和PERIOD的降解，以调节果蝇的睡眠 | Wu, X. | N/A | Mettl5 coordinates protein production and degradation of PERIOD to regulate sleep in Drosophila | |
| NewtCap：一种高效的目标捕获方法，用于提升蝾螈科（真蝾螈和蝾螈）基因组研究 | de Visser, M. C. | N/A | NewtCap: an efficient target capture approach to boost genomic studies in Salamandridae (True Salamanders and Newts) | |
| 一种用于纳米孔直接RNA测序中嵌合体伪影检测的基因组语言模型 | Li, Y. | N/A | A Genomic Language Model for Chimera Artifact Detection in Nanopore Direct RNA Sequencing | |
| 从原始视频到行为分析：一种用于野外活动监测和行为识别的自动化流程 | Silva, L. R. | N/A | From raw footage to behaviour: an automated pipeline for activity monitoring and behaviour identification in the wild | |
| 邻近标记揭示了人类线粒体导入受体蛋白TOMM20和TOMM70的不同相互作用伙伴 | Akram, S. | N/A | Proximity labeling reveals differential interaction partners of the human mitochondrial import receptor proteins TOMM20 and TOMM70 | |
| 微尺度液滴中多能干细胞的培养可调节分化和组织模式化，使其趋向于芯片上的类器官 | Vertti-Quintero, N. | N/A | Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip | |
| 用于选择性捕获和释放肝细胞来源的细胞外囊泡作为肝病生物标志物的磁点击捕获释放技术 | Booijink, R. | N/A | The Mag-Click-Capture-Release Technology for Selective Capture and Release of Hepatocyte-Derived Extracellular Vesicles as Biomarkers for Liver Disease | |
| 单细胞转录组学揭示了硬皮病相关性肺动脉高压与特发性肺动脉高压在病理生物学上的差异，并为精准靶向治疗提供了机会。 | Tuhy, T. | N/A | Single-cell transcriptomics reveal diverging pathobiology and opportunities for precision targeting in scleroderma-associated versus idiopathic pulmonary arterial hypertension | |
| LncRAnalyzer：揭示高粱基因组中的长非编码RNA并探索基因共表达模式 | Nikhil, S. | N/A | LncRAnalyzer: Uncovering Long Non-Coding RNAs and Exploring Gene Co-expression Patterns in Sorghum Genomics | |
| μPIX：利用生成式人工智能实现增强、个性化和可持续的显微镜技术 | Bon, G. | N/A | μPIX: Leveraging Generative AI for Enhanced, Personalized and Sustainable Microscopy | |
| 关于机器学习应用的蛋白质序列中注释的同源区域预处理 | Malhis, N. | N/A | Pre-processing annotated homologous regions in protein sequences concerning machine-learning applications | |
| 改进的蛋白质相互作用模型预测了人类细胞系之间复合物的差异 | Wilkins, G. R. | N/A | Improved protein interaction models predict differences in complexes between human cell lines | |
| 土壤有机质矿化的计算微生物学：利用曲线骨架概念划分计算机断层扫描图像中的三维孔隙空间 | Belghali, Z. | N/A | Computational microbiology of soil organic matter mineralization: Use of the concept of curve skeleton to partition the 3D pore space in computed tomography images | |
| RSV基因组中的G四链体：潜在的抗病毒靶点。 | Bose, D. | N/A | G-quadruplexes in the RSV genome: potential anti-viral targets. | |
| 通过细胞周期实现核组织的三维记忆 | Fujishiro, S. | N/A | Three-dimensional memory of nuclear organization through cell cycles | |
| AcMNPV核衣壳结构揭示了DNA通道组织及环状双链DNA杆状病毒的包装机制。 | Effantin, G. | N/A | Structure of AcMNPV nucleocapsid reveals DNA portal organization and packaging apparatus of circular dsDNA baculovirus. | |
| 乳腺癌转移部位与单一营养水平无关 | Abbott, K. L. | N/A | Site of breast cancer metastasis is independent of single nutrient levels | |
| 通过纳米动力学变化在脂质膜中实现铁死亡的体内成像 | Sonay, A. Y. | N/A | In vivo imaging of ferroptosis through nanodynamic changes in lipid membranes | |
| TFE3融合蛋白在转位性肾细胞癌中驱动氧化代谢、铁死亡抵抗和普遍的RNA合成。 | Davidson, I. | N/A | TFE3 fusion proteins drive oxidative metabolism, ferroptosis resistance and general RNA synthesis in translocation renal cell carcinoma | |
| 植物物种在花蜜过氧化氢含量上存在差异，这是一种某些细菌和酵母能够耐受的抗菌防御机制。 | Landucci, L. | N/A | Plant species vary in nectar peroxide, an antimicrobial defense tolerated by some bacteria and yeasts | |
| 高通量生物多样性调查为最亮的昆虫类群带来了新的见解 | Iwaszkiewicz-Eggebrecht, E. | N/A | High-throughput biodiversity surveying sheds new light on the brightest of insect taxa | |
| 小胶质细胞状态决定多发性硬化症中的病变动态 | van den Bosch, A. M. | N/A | Microglial states determine lesion dynamics in multiple sclerosis | |
| 内源性逆转录病毒样蛋白招募UBQLN2至应激颗粒，并改变其功能特性 | Mohan, H. M. | N/A | Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and alter their functional properties | |
| 模拟微重力加速α-突触核蛋白聚集并诱导体外帕金森病模型中的氧化应激 | Lentini, V. | N/A | Simulated microgravity accelerates alpha-synuclein aggregation and induces oxidative stress in an in vitro Parkinson disease model | |
| 虚拟脑双胞胎的原理与操作 | Hashemi, M. | N/A | Principles and Operation of Virtual Brain Twins | |
| 在烟曲霉感染期间，IFN-STAT1-CYBB轴定义了保护性浆细胞样DC与中性粒细胞之间的交叉对话。 | Guo, Y. | N/A | An IFN-STAT1-CYBB Axis Defines Protective Plasmacytoid DC to Neutrophil Crosstalk During Aspergillus fumigatus Infection. | |
| 心脏骤停小鼠模型中心肌炎症和转录组变化的时序动态 | Panigrahi, S. | N/A | Temporal dynamics of inflammatory and transcriptome changes in the myocardium in a murine model of cardiac arrest | |
| 在多发性硬化症中连接髓鞘与爱泼斯坦-巴尔病毒特异性免疫反应：综合公共T细胞受体库的见解 | Valkiers, S. | N/A | Linking myelin and Epstein-Barr virus specific immune responses in multiple sclerosis: insights from integrated public T cell receptor repertoires | |
| 建立绿色藻类Chlamydomonas incerta作为重组蛋白生产的平台 | Kang, K. | N/A | Establishing the green algae Chlamydomonas incerta as a platform for recombinant protein production | |
| 一种Ⅰ型3' UTR衍生的sRNA参与了金黄色葡萄球菌中的血红素代谢和毒力 | Silard, C. | N/A | A type I 3' UTR-derived sRNA is involved in heme metabolism and virulence in Staphylococcus aureus | |
| Syntaxin11缺乏抑制CRAC通道的启动，从而抑制FHLH4患者T淋巴细胞的细胞毒性和基因表达。 | Vig, M. | N/A | Syntaxin11 Deficiency Inhibits CRAC Channel Priming To Suppress Cytotoxicity And Gene Expression In FHLH4 Patient T Lymphocytes. | |
| 改进的小鼠骨髓损伤模型中通过膜内骨化研究产后骨生成的方法 | Stetsiv, M. | N/A | Improved Methodology for Studying Postnatal Osteogenesis via Intramembranous Ossification in a Murine Bone Marrow Injury Model | |
| 棕榈酰化的输入蛋白α通过与NuMA的相互作用调节有丝分裂纺锤体的定向 | Sutton, P. J. | N/A | Palmitoylated Importin α Regulates Mitotic Spindle Orientation Through Interaction with NuMA | |
| 通过冷冻扫描透射电子断层成像技术捕捉到的线粒体分裂瞬间的影像 | Kirchweger, P. | N/A | Snapshots of Mitochondrial Fission Imaged by Cryo-Scanning Transmission Electron Tomography | |
| G-四链体配体RHPS4通过阻断电离辐射诱导的线粒体质量和活性的增加，破坏了细胞的放射抗性。 | Tricot, S. | N/A | G-quadruplex ligand RHPS4 compromises cellular radio-resistance by blocking the increase in mitochondrial mass and activity induced by ionising irradiation. | |
| 鞘脂类失衡加剧纤维状Tau诱导的内质膜硬化和破裂 | Tittelmeier, J. | N/A | Sphingolipid imbalance aggravates fibrillar Tau-induced endomembrane rigidification and rupture | |
| E3泛素连接酶Trip12在造血干细胞发育过程中减弱Wnt9a/Fzd9b信号传导 | Ensing, J. | N/A | The E3 Ubiquitin Ligase Trip12 attenuates Wnt9a/Fzd9b signaling during hematopoietic stem cell development | |
| PUF RNA结合蛋白FBF-2在不结合RNA的情况下维持干细胞状态。 | Carrick, B. H. | N/A | The PUF RNA-binding protein, FBF-2, maintains stem cells without binding to RNA | |
| 小鼠胚胎在失去与子痫前期相关的丝氨酸蛋白酶前列腺素后红细胞成熟受损 | Di Carlo, S. | N/A | Impaired erythroid maturation in murine embryos upon loss of the preeclampsia-associated serine protease prostasin | |
| 土壤微生物影响植物可塑性的生态和进化 | Bolin, L. G. | N/A | Soil microbes influence the ecology and evolution of plant plasticity | |
| 基因和系统基因组的不一致揭示了温带Loliinae草本植物中的冲突杂交事件 | Moreno-Aguilar, M. F. | N/A | Genic and phylogenomic discordances reveal conflicting hybridization episodes in temperate Loliinae grasses | |
| 欧洲小麦白粉病的群体基因组学与分子流行病学研究 | Jigisha, J. | N/A | Population genomics and molecular epidemiology of wheat powdery mildew in Europe | |
| 酵母细胞裂解突变体cly8是ESP1的一个温度敏感等位基因。 | Putnam, C. D. | N/A | The Saccharomyces cerevisiae cell lysis mutant cly8 is a temperature-sensitive allele of ESP1 | |
| 人鼠蛋白质组学揭示了阿尔茨海默病与淀粉体中蛋白质周转延迟的共同通路 | Yarbro, J. M. | N/A | Human-mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome | |
| EpigeneticAgePipeline：一个用于从甲基化微阵列全面评估表观遗传年龄指标的R包 | Rayevskiy, S. | N/A | EpigeneticAgePipeline: an R package for comprehensive assessment of epigenetic age metrics from methylation microarrays | |
| 重建过去的插入缺失的算法：仅删除的简约性问题 | Moutet, J. | N/A | Algorithms to reconstruct past indels: the deletion-only parsimony problem | |
| 胶质母细胞瘤化疗耐药性的获得和逆转是由Rho GTPase通路介导的。 | Magalhaes, Y. T. | N/A | Acquisition and reversal of glioblastoma chemoresistance are mediated by the Rho GTPase pathway | |
| CHK1介导的TOP1催化活性调控抑制了复制和转录相关的基因组不稳定性 | Majumdar, A. G. | N/A | CHK1-mediated regulation of TOP1 catalytic activity suppresses replication and transcription-associated genomic instability | |
| 体内表达与SCA27A相关的FGF14突变会导致半合子不足及小脑浦肯野神经元放电受损 | Ransdell, J. L. | N/A | In Vivo Expression of an SCA27A-linked FGF14 Mutation Results in Haploinsufficiency and Impaired Firing of Cerebellar Purkinje Neurons | |
| 可分离的默认模式网络连接模式构成了精神病风险中不同症状的基础 | Ajunwa, C. C. | N/A | Dissociable Default Mode Network Connectivity Patterns Underlie Distinct Symptoms in Psychosis Risk | |
| 听觉工作记忆在音乐能力与听觉流分离之间的关系中起中介作用。 | Liu, M. | N/A | Auditory working memory mediates the relationship between musicianship and auditory stream segregation | |
| F-BAR蛋白CIP4和FBP17在皮层神经元的径向迁移和突起生长中发挥作用。 | English, L. A. | N/A | F-BAR proteins CIP4 and FBP17 function in cortical neuron radial migration and process outgrowth | |
| 前脑岛中的多巴胺传递塑造了焦虑的神经编码 | COUDERC, Y. | N/A | Dopamine transmission in the anterior insula shapes the neural coding of anxiety | |
| # BioRxiv 2024-10-24 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 基于映射的基因组大小估计 | Natarajan, S. | N/A | Mapping-based genome size estimation | |
| 恶性疟原虫配子体的数量和比例从急性感染到慢性寄生虫携带状态有所不同，尽管性成熟率保持不变。 | van Dijk, H. | N/A | Number and proportion of P. falciparum gametocytes vary from acute infection to chronic parasite carriage despite unaltered sexual commitment rate | |
| 果蝇鞘神经胶质细胞、星形胶质细胞和神经元中的睡眠、进食和代谢稳态动力学 | Flores-Valle, A. | N/A | Dynamics of sleep, feeding, and metabolic homeostasis in Drosophila ensheathing glia, astrocytes, and neurons | |
| 非经典端粒酶逆转录酶通过STAT5调控主动脉瓣细胞的成骨性重编程 | Cuevas, R. A. | N/A | Non-canonical Telomerase Reverse Transcriptase Controls Osteogenic Reprogramming of Aortic Valve Cells Through STAT5 | |
| 砍伐改变了热带森林的结构，而将其转化为农业用地则降低了生物多样性和生态功能。 | Marsh, C. J. | N/A | Logging alters tropical forest structure, while conversion to agriculture reduces biodiversity and functioning | |
| 建模信心判断停止规则中的速度-准确性权衡 | Herregods, S. | N/A | Modelling Speed-Accuracy Tradeoffs in the Stopping Rule for Confidence Judgments | |
| 撤回：纳米盘重构的大肠杆菌趋氧受体中的信号转导与激酶调控 | Maschmann, Z. A. | N/A | WITHDRAWN: Signal Transduction and Kinase Control in Nanodisc Reconstituted E. coli Aerotaxis Receptor | |
| 深度主动学习在生物医学分割中的鲁棒性 | Arikan, M. | N/A | Deep Active Learning for Robust Biomedical Segmentation | |
| 利用新的数据资源来定义新型隐球菌对环境信号的反应 | Kang, Y. S. | N/A | Leveraging a new data resource to define the response of C. neoformans to environmental signals | |
| 从单个解剖学上共定位的细胞重建库中提取近似连接组的方法 | Manjunatha, K. K. H. | N/A | A method for extracting an approximated connectome from libraries of single anatomically co-registered cell reconstructions | |
| 通过数据驱动的标度律解码朊病毒样结构域的相分离 | Maristany, M. J. | N/A | Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws | |
| 骨形态发生蛋白信号通路中的突变使斑马鱼和人类对乙醇诱导的下颌畸形更为敏感 | Klem, J. R. | N/A | Mutation in the Bone Morphogenetic Protein signaling pathway sensitize zebrafish and humans to ethanol-induced jaw malformations | |
| 原位近原子分辨率下的核糖体动态快照：全面洞察真核延伸循环 | Zhang, X. | N/A | Snapshots of ribosome dynamics near atomic-resolution in situ: full insight into the eukaryotic elongation cycle | |
| ATR通过从头胆固醇合成促进mTORC1活性。 | Tangudu, N. K. | N/A | ATR promotes mTORC1 activity via de novo cholesterol synthesis | |
| 可修改的临床牙科印模方法，用于从脊椎动物获取全口及详细的牙齿特征 | Wibisana, J. N. | N/A | Modifiable clinical dental impression methods to obtain whole-mouth and detailed dental traits from vertebrates | |
| KRAB锌指基因和转座元件的调控网络在人类大脑进化和疾病过程中发生了变化 | Chen, Y.-C. | N/A | Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease | |
| 山松甲虫在不同寄主抗性的森林中蔓延 | Brush, M. | N/A | Mountain pine beetle spread in forests with varying host resistance | |
| 微生介导入侵的统一理论 | Martignoni, M. M. | N/A | Toward a unified theory of microbially-mediated invasion | |
| 成本效益权衡在练习过程中调节了基于规则到基于记忆的处理转变 | Yang, G. | N/A | Cost-benefit Tradeoff Mediates the Rule- to Memory-based Processing Transition during Practice | |
| 可泛化的情感投入和脱离神经模型 | Nanni Zepeda, M. | N/A | Generalizable Neural Models of Emotional Engagement and Disengagement | |
| SEGUID v2：扩展SEGUID校验和以适用于环状、线性、单链和双链生物序列 | Pereira, H. | N/A | SEGUID v2: Extending SEGUID checksums for circular, linear, single- and double-stranded biological sequences | |
| mm2-gb：用于长读DNA比对的GPU加速Minimap2 | Dong, J. | N/A | mm2-gb: GPU Accelerated Minimap2 for Long Read DNA Mapping | |
| 作为进化驱动力的可移动元件在仙人掌嗜好果蝇物种宿主转移中的作用 | Oliveira, D. S. d. | N/A | Transposable elements as evolutionary driving force to host shift in cactophilic Drosophila species | |
| 在V1皮层柱模型中，细胞类型的特定放电模式取决于前馈和反馈驱动状态。 | Moreni, G. | N/A | Cell type specific firing patterns in a V1 cortical column model depend on feedforward and feedback-driven states | |
| 氨基酸招募进入遗传密码的顺序由最后普遍共同祖先的蛋白质域解析 | Wehbi, S. | N/A | Order of amino acid recruitment into the genetic code resolved by Last Universal Common Ancestor's protein domains | |
| 5-HT1A受体在斑马鱼对潜在威胁的反应及社交性中的作用 | de Sousa, L. V. X. B. | N/A | Roles of the 5-HT1A receptor in zebrafish responses to potential threat and in sociality | |
| 羽纹硅藻中细胞大小感知和接合型分化的分子指纹 | Belisova, D. | N/A | Molecular fingerprints of cell size sensing and mating type differentiation in pennate diatoms | |
| 栖息地破碎化介导了长期气候驱动下鸟类喜温性变化的机制 | Liu, J. | N/A | Habitat fragmentation mediates the mechanisms underlying long-term climate-driven thermophilization in birds | |
| 铁死亡抑制对抗代谢紊乱并改善肺动脉环扎猪的心脏功能 | Kazmirczak, F. | N/A | Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs | |
| 发现荧光：利用社区科学记录新型生物荧光现象，并促进社区参与科学活动 | Burke, H. | N/A | Finding Fluorescence: Utilizing community science to document novel biofluorescence occurrences and encourage community engagement in science | |
| 通过神经反馈实现对远程海马表征的闭环调制 | Coulter, M. E. | N/A | Closed-loop modulation of remote hippocampal representations with neurofeedback | |
| 在阿尔茨海默病的小鼠模型中，微生物群以性别特异性的方式影响免疫反应。 | Bostick, J. W. | N/A | The microbiome shapes immunity in a sex-specific manner in mouse models of Alzheimer's disease | |
| 阿尔茨海默病相关保护性变异Plcg2-P522R以性别二态性方式调节外周巨噬细胞功能 | Staley, H. A. | N/A | Alzheimer's disease-associated protective variant Plcg2-P522R modulates peripheral macrophage function in a sex-dimorphic manner | |
| 针对动物体内特定基因组DNA序列的靶向诱变，以生成体内变异文库 | Falo-Sanjuan, J. | N/A | Targeted mutagenesis of specific genomic DNA sequences in animals for the in vivo generation of variant libraries | |
| 17α-雌二醇治疗对内分泌系统的影响通过下丘脑单核转录组测序揭示 | Li, L. | N/A | The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus | |
| AIVE：通过全面分析准确预测SARS-CoV-2感染性 | Park, J. | N/A | AIVE: accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis | |
| 小鼠大脑的左右脑神经解剖学广泛不对称性 | Silberfeld, A. | N/A | Left-Right Brain-Wide Asymmetry of Neuroanatomy in the Mouse Brain | |
| 西欧沿海沙丘中植物相关无脊椎动物群落结构的驱动因素 | Van De Walle, R. | N/A | Drivers of plant-associated invertebrate community structure in West-European coastal dunes | |
| 全组织成像：亚微米分辨率下的细胞边界成像用于自动细胞分割——在外胚层附属物上皮弯曲中的应用 | Norris, S. C. P. | N/A | Whole Tissue Imaging of Cellular Boundaries at Sub-Micron Resolutions for Automatic Cell Segmentation: Applications in Epithelial Bending of Ectodermal Appendages | |
| 不平衡基因组中RNA m6A甲基化的动态变化及其调控作用 | Zhang, S. | N/A | Dynamics and Regulatory Roles of RNA m6A Methylation in Unbalanced Genomes | |
| 胶质细胞调控嗅觉关键期中的经验依赖性可塑性 | Leier, H. C. | N/A | Glia control experience-dependent plasticity in an olfactory critical period | |
| 人类目标导向动作的准备涉及皮质脊髓神经计算的混合。 | Wadsley, C. G. | N/A | Goal-directed action preparation in humans entails a mixture of corticospinal neural computations | |
| 一种能够穿过血脑屏障的神经肽-神经降压素偶联物，在小鼠癫痫持续状态后诱导了具有抗惊厥、神经保护和抗炎特性的药理性低体温。 | Ferhat, L. | N/A | A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice | |
| 运动序列特异性学习诱导的皮层脊髓可塑性偏向于感觉运动μ节律的峰值相位 | Suresh, T. | N/A | Motor sequence-specific learning-induced corticospinal plasticity is biased towards sensorimotor mu rhythm peak phases | |
| 自我关联通过自动优先处理社会显著信号来增强早期注意力选择 | Scheller, M. | N/A | Self-association enhances early attentional selection through automatic prioritization of socially salient signals | |
| 基于新型扩增子的方法用于HIV-1 M组重组形式近全长基因组（NFLG）测序 | Moscona, R. | N/A | Novel Amplicons based Method for Near-Full-Length Genome (NFLG) Sequencing of HIV-1 Group M Recombinant Forms | |
| 一种基于原则的区域间皮层网络社区检测方法 | Armas, J. S. M. | N/A | A principled approach to community detection in interareal cortical networks | |
| 使用泛基因组进行基因型序列解析的拷贝数变异，揭示了重复基因的同源特异性全球多样性及表达分化 | Ma, W. | N/A | Genotyping sequence-resolved copy-number variation using pangenomes reveals paralog-specific global diversity and expression divergence of duplicated genes | |
| 通过多模态蛋白质-配体对比学习提升挑战性目标筛选 | Wang, Z. | N/A | Enhancing Challenging Target Screening via Multimodal Protein-Ligand Contrastive Learning | |
| 神经扫描：通过解剖网络的时空整合探索神经发育 | Koonce, N. L. | N/A | NeuroSCAN: Exploring Neurodevelopment via Spatiotemporal Collation of Anatomical Networks | |
| UBE3C和NRF1依赖的蛋白酶体途径对急性蛋白质聚集物周转的时间控制 | Hickey, K. L. | N/A | Temporal control of acute protein aggregate turnover by UBE3C and NRF1-dependent proteasomal pathways | |
| 灵长类尾状核在多模态决策中的独特神经结构及其关键作用 | ZENG, Z. | N/A | Distinct neural manifolds and critical roles of primate caudate nucleus in multimodal decision-making | |
| SARS-CoV-2主蛋白酶活性位点环的构象空间由配体结合和蛋白质间别构效应决定。 | Lee, E. | N/A | The Conformational Space of the SARS-CoV-2 Main Protease Active Site Loops is Determined by Ligand Binding and Interprotomer Allostery | |
| 在发声新颖性的进化过程中，运动皮层投射的选择性扩展 | Isko, E. C. | N/A | Selective expansion of motor cortical projections in the evolution of vocal novelty | |
| 免疫样糖识别与横向获得性糖加工协同调控微生物内共生中的宿主控制 | Jenkins, B. H. | N/A | Immune-like glycan-sensing and horizontally-acquired glycan-processing orchestrate host control in a microbial endosymbiosis | |
| 制造感知的生成模型架构能够实现生物序列的设计和合成，达到千万亿次规模 | Weinstein, E. N. | N/A | Manufacturing-Aware Generative Model Architectures Enable Biological Sequence Design and Synthesis at Petascale | |
| 解析铜绿假单胞菌对亚胺培南耐药性的蛋白质组学图谱：临床与对照菌株的比较研究 | Eidsaa, M. | N/A | Unravelling the Proteomic Landscape of Imipenem Resistance in Pseudomonas aeruginosa: A Comparative Investigation between Clinical and Control Strains | |
| 母体脂联素恢复了暴露于宫内母体肥胖的成年后代阻力血管中的胆碱能血管舒张 | Murphy, M. | N/A | Maternal adiponectin restores cholinergic vasodilation in resistance vessels from adult offspring exposed to maternal obesity in utero | |
| 反复的基因渐渗和地理分层塑造了新热带地区的酿酒酵母（Saccharomyces cerevisiae） | Avelar-Rivas, J. A. | N/A | Recurrent introgression and geographical stratification shape Saccharomyces cerevisiae in the Neotropics | |
| 尾洛辛介导的软腐欧氏杆菌属细菌间的相互作用 | Borowicz, M. | N/A | Tailocin-mediated interactions in Soft Rot Pectobacteriaceae | |
| 一项简单的措施可减少高脂肪饮食摄入并降低小鼠肥胖率 | Barrett, M. R. | N/A | A simple action reduces high fat diet intake and obesity in mice | |
| 对古老干燥样本中的RNA进行测序，揭示了过去的病毒群以及长期存活的RNA的特性。 | Keene, A. H. | N/A | Sequencing RNA from old, dried specimens reveals past viromes and properties of long-surviving RNA | |
| 生物膜流丝的应力硬化行为 | Savorana, G. | N/A | Stress-hardening behaviour of biofilm streamers | |
| 重新审视雄蚊不吸血的范式 | Bozic, J. | N/A | Revisiting the paradigm of anhematophagy in male mosquitoes | |
| 纳米抗体表位预测中的AI驱动方法：我们是否已经到达？ | Eshak, F. | N/A | AI driven approaches in Nanobody Epitope Prediction: Are We There Yet? | |
| 探索用于抗体序列设计排名的对数似然评分 | Ucar, T. | N/A | Exploring Log-Likelihood Scores for Ranking Antibody Sequence Designs | |
| 焦虑/抑郁的个体在认知冲突编码过程中表现出前额叶-颞叶同步性中断。 | Shekara, A. | N/A | Anxious/depressed individuals exhibit disrupted frontotemporal synchrony during cognitive conflict encoding | |
| Dnajc3（HSP40）调节小鼠视神经的轴突再生 | Wang, J. | N/A | Dnajc3 (HSP40) Modulates Axon Regeneration in the Mouse Optic Nerve | |
| 通过基因集嵌入揭示潜在的生物功能关联 | Huang, Y. | N/A | Uncovering Latent Biological Function Associations through Gene Set Embeddings | |
| 保留隐藏的层次结构：用于增强基因组序列分析的庞加莱距离 | Ali, S. | N/A | Preserving Hidden Hierarchical Structure: Poincare Distance for Enhanced Genomic Sequence Analysis | |
| 半监督组学因子分析（SOFA）从多组学数据中的潜在因子中分离出已知的变异来源。 | Capraz, T. | N/A | Semi-supervised Omics Factor Analysis (SOFA) disentangles known sources of variation from latent factors in multi-omics data | |
| 增强小鼠发声的皮层运动神经元投射 | Boyd, J. L. | N/A | Enhancing cortico-motoneuronal projections for vocalization in mice | |
| 有丝分裂纺锤体的方向和动力学通过NuMA定位在各向异性组织拉伸的精细调节下得以实现。 | Tarannum, N. | N/A | Mitotic spindle orientation and dynamics are fine-tuned by anisotropic tissue stretch via NuMA localisation | |
| 青光眼视网膜神经节细胞（RGC）死亡与眼压（IOP）诱导的血视网膜屏障破坏有关。 | Zhang, C. | N/A | IOP-induced blood-retinal barrier compromise contributes to RGC death in glaucoma | |
| B细胞表达的酶PexRAP，作为醚脂生物合成中的中间体，促进了抗体反应和生发中心的大小。 | Cho, S. H. | N/A | B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size | |
| 在异种Caenorhabditis胚胎的单细胞阶段出现了杂交不亲和性。 | Bloom, J. | N/A | Hybrid incompatibility emerges at the one-cell stage in interspecies Caenorhabditis embryos | |
| 尖峰皮层及其连接网络中的结构妥协 | Sahlas, E. | N/A | Structural compromise in spiking cortex and connected networks | |
| 地球上最古老生物潘多中的体细胞突变镶嵌图 | Pineau, R. | N/A | Mosaic of Somatic Mutations in Earth's Oldest Living Organism, Pando | |
| Rag2Mol：基于检索增强生成的结构化药物设计 | Zhang, P.-D. | N/A | Rag2Mol: Structure-based drug design based on Retrieval Augmented Generation | |
| 基底神经节输出的计算瓶颈（以及应对方法） | Humphries, M. D. | N/A | The computational bottleneck of basal ganglia output (and what to do about it) | |
| α-突触核蛋白株系动力学与帕金森病中的认知转变相关 | Gadhave, K. | N/A | α-Synuclein Strain Dynamics Correlate with Cognitive Shifts in Parkinson's Disease | |
| 蚊虫调查揭示了马拉维蚊子在桑给巴尔市繁殖地点的偏好。 | Hill, K. | N/A | Larval surveys reveal breeding site preferences of malaria vector Anopheles spp. in Zanzibar City | |
| 丹曲林对携带严重恶性高热突变Y522S的雷诺定受体1的抑制作用通过冷冻电镜可视化 | Iyer, K. A. | N/A | Dantrolene inhibition of ryanodine receptor 1 carrying the severe malignant hyperthermia mutation Y522S visualized by cryo-EM | |
| PACT通过防止内源性双链RNA异常激活PKR，而无需隔离。 | Ahmad, S. | N/A | PACT prevents aberrant activation of PKR by endogenous dsRNA without sequestration | |
| 依赖于HuR的RyR2表达有助于棕色脂肪细胞中钙介导的产热作用 | Guarnieri, A. R. | N/A | HuR-dependent expression of RyR2 contributes to calcium-mediated thermogenesis in brown adipocytes | |
| 入侵太阳珊瑚（Tubastrea spp.）在里约热内卢海岸的模拟幼虫扩散：亚中尺度丝状体在离岸运输和连通性中的作用 | Calado, L. | N/A | Simulated larvae dispersion of the invasive sun-coral (Tubastrea spp.) along Rio de Janeiro's coast: the role of submesoscale filaments on offshore transport and connectivity | |
| 在早更新世到中更新世过渡期间，人类经历了严重瓶颈的证据不足。 | Durvasula, A. | N/A | Insufficient evidence for a severe bottleneck in humans during the Early to Middle Pleistocene transition | |
| 利用自然序列变异在胚胎发生过程中情境化转录因子结合 | Sigalova, O. M. | N/A | Contextualising transcription factor binding during embryogenesis using natural sequence variation | |
| 低保真度DNA聚合酶IV加速了铜绿假单胞菌的基因组进化 | Castell, S. | N/A | Low fidelity DNA polymerase IV accelerates genome evolution in Pseudomonas aeruginosa | |
| 用于研究RNA结构的生物正交环丙烯酮 | Chen, S. | N/A | Bioorthogonal cyclopropenones for investigating RNA structure | |
| 人类肠道共生菌阿利斯蒂普斯·蒂莫内西斯（Alistipes timonensis）能够调节宿主的脂质组，并向宿主传递抗炎的外膜囊泡，从而在白介素10缺陷的小鼠模型中抑制结肠炎。 | Older, E. A. | N/A | Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10-deficient mouse model | |
| II型-B CRISPR-Cas增强特异性的机制 | Hibshman, G. N. | N/A | Mechanism of type II-B CRISPR-Cas enhanced specificity | |
| 对于植物来说真实的情况，对于三角褐指藻（Phaeodactylum tricornutum）可能并不适用：香草兰（Vanilla planifolia）的香草醛合成酶（VpVAN）被靶向到硅藻的四个亚细胞区室中的情况。 | Diaz-Garza, A. M. | N/A | What is true for plants may not be true for Phaeodactylum tricornutum: The case of Vanilla planifolia vanillin synthase (VpVAN) targeted to four subcellular compartments of the diatom. | |
| 裸盖菇素减少了SAPAP3基因敲除小鼠模型中强迫行为的梳理行为 | Gattuso, J. J. | N/A | Psilocybin Reduces Grooming in the SAPAP3 Knockout Mouse Model of Compulsive Behaviour | |
| 语言网络历久弥新：老年人脑中保留的选择性、侧化及网络内功能同步性 | Billot, A. | N/A | The language network ages well: Preserved selectivity, lateralization, and within-network functional synchronization in older brains | |
| 鉴定细胞周期蛋白L1作为调控乙型肝炎病毒复制的宿主因子 | Owino, C. O. | N/A | Identification of Cyclin L1 as a host factor regulating Hepatitis B Virus replication | |
| 结核菌噬菌体毒力比较研究 | Rubino, I. | N/A | Comparative study on the virulence of mycobacteriophages | |
| 比较基因组分析揭示了水体中拉氏菌属（Ralstonia spp.）致病性的降低 | Liu, g. | N/A | Comparative genomic analysis reveals reduced pathogenicity of Ralstonia spp. in water | |
| SETD2促进PAF1C与延伸中的RNA聚合酶II的相互作用，并且对于神经分化是必需的。 | Ambrosi, C. | N/A | SETD2 promotes PAF1C interactions with the elongating RNA Pol II and is required for neuronal differentiation | |
| RTL4是一种与自闭症谱系障碍相关的逆转录病毒衍生基因，是一种微胶质细胞基因，在出生后的大脑中对去甲肾上腺素产生反应。 | Ishino, F. | N/A | RTL4, a retrovirus-derived gene implicated in autism spectrum disorder, is a microglial gene that responds to noradrenaline in the postnatal brain | |
| RTL4是一种与自闭症谱系障碍相关的逆转录病毒衍生基因，是一种对出生后大脑中的去甲肾上腺素产生反应的微胶质细胞基因。 | Ishino, F. | N/A | RTL4, a retrovirus-derived gene implicated in autism spectrum disorder, is a microglial gene that responds to noradrenaline in the postnatal brain | |
| 四棘刺鱼（Apeltes quadracus）具有XY性染色体系统，其X和Y染色体上均存在多态性倒位。 | Liu, Z. | N/A | The fourspine stickleback (Apeltes quadracus) has an XY sex chromosome system with polymorphic inversions on both X and Y chromosomes | |
| 使用分层变压器进行机制性的基因型-表型转换 | Lee, I. | N/A | Mechanistic genotype-phenotype translation using hierarchical transformers | |
| LUNAR：一种利用综合基因组和临床数据预测胶质瘤复发的深度学习模型 | Patricoski-Chavez, J. A. | N/A | LUNAR: A Deep Learning Model to Predict Glioma Recurrence Using Integrated Genomic and Clinical Data | |
| 进化中新出现的脑结构的可变存在与特质冲动性相关 | Willbrand, E. H. | N/A | Variable Presence of an Evolutionarily New Brain Structure is Related to Trait Impulsivity | |
| 表示相似性分析、中心核对齐和典型相关分析之间的等价性 | Williams, A. H. | N/A | Equivalence between representational similarity analysis, centered kernel alignment, and canonical correlations analysis | |
| BBSome亚基耗竭通过TGF-β信号通路改变受体内吞作用并促进上皮-间质转化 | Solarat, C. | N/A | Depletion of BBSome Subunits Alters Receptor Endocytosis and Promotes EMT via TGF-β Signaling | |
| 尿液生化生态学揭示了微生物组-代谢物相互作用和复发性尿路感染的代谢标志物 | Neugent, M. L. | N/A | Urinary biochemical ecology reveals microbiome-metabolite interactions and metabolic markers of recurrent urinary tract infection | |
| 毒力因子与信号分子的相互作用：白蛋白和钙介导的支气管败血博德特菌生物膜调控 | Mugni, S. L. | N/A | Interplay of Virulence Factors and Signaling Molecules: Albumin and Calcium-Mediated Biofilm Regulation in Bordetella bronchiseptica | |
| 丰富的环境需要对海马旁神经网进行重塑，以在阿尔茨海默病小鼠模型中触发记忆改善 | Bouisset, G. | N/A | Enriched environment requires remodeling of hippocampal perineuronal nets to trigger memory improvement in Alzheimer's mouse model | |
| 冲动的青少年在解码面部表情情绪时表现出处理效率低下和决策阈值较低的特点。 | Schreiber, A. M. | N/A | Impulsive adolescents exhibit inefficient processing and a low decision threshold when decoding facial expressions of emotions | |
| 新的治疗组合，以增强针对胶质母细胞瘤细胞中EGFR的抗体和核酸适体的内吞作用 | Cruz Da Silva, E. | N/A | New therapeutic combination to enhance endocytosis of antibodies and nucleic-acid aptamers targeting EGFR in glioblastoma cells | |
| NINJ1在溶细胞死亡期间通过钙驱动的质膜脂质混杂而被激活。 | Borges, J. P. | N/A | NINJ1 is activated by calcium-driven plasma membrane lipid scrambling during lytic cell death | |
| Nance-Horan综合征样1通过与内皮素和Ena/VASP蛋白相互作用，促进快速内皮素介导的内吞作用。 | Cope, J. F. W. | N/A | Nance-Horan Syndrome-like 1 interacts with endophilin and Ena/VASP proteins to promote fast endophilin-mediated endocytosis. | |
| Nance-Horan综合征样1与内菲林和Ena/VASP蛋白相互作用，促进快速内菲林介导的内吞作用。 | Cope, J. F. W. | N/A | Nance-Horan Syndrome-like 1 interacts with endophilin and Ena/VASP proteins to promote fast endophilin-mediated endocytosis. | |
| 极端干旱期间的进化救援 | Anstett, D. N. | N/A | Evolutionary rescue during extreme drought | |
| Pipeasm：一种用于自动化大型染色体规模基因组组装和评估的工具 | Silva, B. M. | N/A | Pipeasm: a tool for automated large chromosome-scale genome assembly and evaluation | |
| E3泛素连接酶NEDD4L通过降解PRMT5来抑制AKT/mTOR信号通路，从而防止结直肠癌肝转移。 | Dong, Z. | N/A | The E3 ligase NEDD4L prevents colorectal cancer liver metastasis via degradation of PRMT5 to inhibit the AKT/mTOR signaling pathway | |
| 身体不满塑造了时间感知与内感受的相互作用 | Rusinova, A. | N/A | Body dissatisfaction shapes time perception and interoception interplay | |
| 基因变异的相互作用激活酵母中潜在的代谢途径 | Sasikumar, S. | N/A | Interaction of Genetic Variants Activates Latent Metabolic Pathways in Yeast | |
| 组织适应性Tregs利用炎症信号促进肠道从治疗相关损伤中修复 | Fischer, J. C. | N/A | Tissue-adapted Tregs harness inflammatory signals to promote intestinal repair from therapy-related injury | |
| 鸟类沿经线方向迁徙，以响应青藏高原隆升所导致的亚洲季风效应。 | Zhang, W. | N/A | Birds migrate longitudinally in response to the resultant Asian monsoons of the Qinghai-Tibet Plateau uplift | |
| 快速寿命的脊椎动物宿主具有更高的蚊媒寄生虫传播潜力 | Dahlin, K. J.- M. | N/A | Fast-lived Vertebrate Hosts Exhibit Higher Potential for Mosquito-borne Parasite Transmission | |
| 果蝇翅膀上的性选择目标 | De Lisle, S. P. | N/A | Targets of sexual selection on the Drosophila wing | |
| 病原体启动改变了野生鸣禽宿主的传播潜力和传播能力预测因子 | Leon, A. E. | N/A | Pathogen priming alters host transmission potential and predictors of transmissibility in a wild songbird species | |
| 双trxG/PcG蛋白ULTRAPETALA1调控H3K27me3，并直接增强POLYCOMB抑制复合物2的活性，以实现精细调控的生殖转换 | Geshkovski, V. | N/A | The dual trxG/PcG protein ULTRAPETALA1 modulates H3K27me3 and directly enhances POLYCOMB REPRESSIVE COMPLEX 2 activity for fine-tuned reproductive transitions | |
| Bur1驱动的G1到S期转变诱导了酵母检查点突变体的羟基脲敏感性 | da Silva, S. C. R. | N/A | Bur1-driven G1-to-S phase transition induces hydroxyurea sensitivity in yeast checkpoint mutants | |
| Hippo-vgll3信号可能通过不同的脂肪动态影响大西洋鲑鱼成熟年龄的性别差异。 | Ahi, E. P. | N/A | Hippo-vgll3 signaling may contribute to sex differences in Atlantic salmon maturation age via contrasting adipose dynamics | |
| 许多实验室血吸虫种群中保留了丰富的遗传变异。 | Jutzeler, K. S. | N/A | Abundant genetic variation is retained in many laboratory schistosome populations | |
| 查尔酮异构酶的自然变异定义了控制黑杨种群间生长变异的主要位点 | Durufle, H. | N/A | Natural variation in chalcone isomerase defines a major locus controlling growth variation between Populus nigra populations | |
| 香烟烟雾成分对-苯醌对人红细胞结构与功能的影响 | Yadav, N. | N/A | Effect of p-benzoquinone, a cigarette smoke-derived component, on the architecture and function of human RBC | |
| 工程化细菌微室壳中的受控酶货物装载 | Tefft, N. M. | N/A | Controlled enzyme cargo loading in engineered bacterial microcompartment shells | |
| 麦角固醇和7-脱氢胆固醇及其内过氧化物的比较研究：生成、鉴定及其对磷脂膜和黑色素瘤细胞的影响 | Yukuyama, M. N. | N/A | Comparative study of Ergosterol and 7-dehydrocholesterol and their Endoperoxides: Generation, Identification and Impact in Phospholipid Membranes and Melanoma Cells | |
| ConvNTC：用于预测疾病相关miRNA对和细胞相关药物对的卷积神经张量补全 | Liu, P. | N/A | ConvNTC: Convolutional neural tensor completion for predicting the disease-related miRNA pairs and cell-related drug pairs | |
| 揭示表位特异性TCR库的隐藏序列分布及其对机器学习模型性能的影响 | Gielis, S. | N/A | Revealing the hidden sequence distribution of epitope-specific TCR repertoires and its influence on machine learning model performance | |
| ProteoSeeker：一款功能丰富的宏基因组分析工具，用于便捷且全面的宏基因组探索 | Filis, G. | N/A | ProteoSeeker: A Feature-Rich Metagenomic Analysis Tool for Accessible and Comprehensive Metagenomic Exploration | |
| 通过互补的综合结构生物学方法解析GPCR-G蛋白受体相互作用的分子决定因素 | Castel, J. | N/A | Deciphering molecular determinants of GPCR-G protein receptor interactions by complementary integrative structural biology methods | |
| 多聚磷酸盐比DNA更有效地区分蛋白质构象系综，促进多样化的组装和成熟行为。 | Goyal, S. | N/A | Polyphosphate Discriminates Protein Conformational Ensembles More Efficiently than DNA Promoting Diverse Assembly and Maturation Behaviors | |
| 时空谱系追踪揭示了肿瘤生长和转移的动态空间结构 | Jones, M. G. | N/A | Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis | |
| 周期素G相关激酶（GAK）是一种新型的有丝分裂激酶，也是弥漫性大B细胞淋巴瘤的治疗靶点。 | Lightfuss, O. B. | N/A | The cyclin-G associated kinase (GAK) is a novel mitotic kinase and therapeutic target in diffuse large B-cell lymphoma | |
| NSD2通过整合素/FAK/AKT信号传导促进细胞硬度趋向性，并驱动从多囊肾病向囊性肾细胞癌的转变 | Feng, W. | N/A | NSD2 promotes cell durotaxis and drives the transition from PKD to tubulocystic renal cell carcinoma through integrin/FAK/AKT signaling | |
| 抑制肿瘤相关巨噬细胞中的PIM激酶可抑制炎症小体1的激活，并增强前列腺癌对免疫治疗的敏感性。 | Clements, A. N. | N/A | Inhibition of PIM kinase in tumor associated macrophages suppresses inflammasome 1 activation and sensitizes prostate cancer to immunotherapy | |
| 富集于突触信号传导的转录模式与高级别浆液性卵巢癌患者较短的生存期相关 | Bhattacharya, A. | N/A | Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer | |
| 高级别浆液性卵巢癌中肿瘤-免疫动态的时间模型 | Egan, D. | N/A | A TEMPORAL MODEL OF TUMOR-IMMUNE DYNAMICS IN HIGH GRADE SEROUS OVARIAN CANCER | |
| 羟基聚乙二醇：一种有效规避人体预存抗PEG抗体的解决方案，以实现高效递送 | Ding, T. | N/A | Hydroxy polyethylene glycol: a solution to evade human pre-existing anti-PEG antibodies for efficient delivery | |
| 血压变异性损害中年小鼠的血管功能 | Mendiola, P. J. | N/A | Blood pressure variability compromises vascular function in middle-aged mice | |
| 有氧能力与运动通过增强胆汁酸代谢来介导对肝脏脂肪变性的保护作用。 | Kugler, B. A. | N/A | Aerobic capacity and exercise mediate protection against hepatic steatosis via enhanced bile acid metabolism. | |
| 从转录组数据驱动的布尔网络推断以预测细胞分化与重编程 | Chevalier, S. | N/A | Data-driven inference of Boolean networks from transcriptomes to predict cellular differentiation and reprogramming | |
| 通过单细胞RNA测序解析强直性脊柱炎中的代谢途径及蛋白质相互作用网络 | Yarici, M. | N/A | Deciphering Metabolic Pathways and Protein-Protein Interaction Networks in Ankylosing Spondylitis through Single-Cell RNA Sequencing | |
| 基于核滤波的自适应控制器在网络遗传学应用中的应用 | Smart, B. C. | N/A | Kernel Filter-Based Adaptive Controllers For Cybergenetics Applications | |
| 口服耐受的系统效应改善了身体不同部位多个和同时发生的伤口的愈合 | Nobrega, I. B. C. | N/A | Systemic effects of oral tolerance improve the healing of several and concomitant wounds in different body parts | |
| 维生素E补充剂可防止老年小鼠圆形精子细胞发生铁死亡 | Germeraad, J. | N/A | Vitamin E supplementation prevents ferroptosis in round spermatids of aged mice | |
| RDAforest：识别多基因适应的环境驱动因素。 | Matz, M. V. | N/A | RDAforest: identifying environmental drivers of polygenic adaptation. | |
| 解析遗传性和可塑性对弗里蒙特杨树叶反射率在温度梯度上的影响 | Seeley, M. M. | N/A | Disentangling the effect of heritability and plasticity on Populus fremontii leaf reflectance across a temperature gradient | |
| CADET：利用eQTL汇总数据在混合样本中增强转录组范围的关联分析 | Head, S. T. | N/A | CADET: Enhanced transcriptome-wide association analyses in admixed samples using eQTL summary data | |
| GL15与FDL1之间的遗传相互作用调节了玉米幼苗角质层的沉积和叶片通透性 | Castorina, G. | N/A | Genetic interaction between GL15 and FDL1 modulates juvenile cuticle deposition and leaf permeability in maize | |
| 猕猴桃病原菌丁香假单胞菌猕猴桃致病变种3型的基因组生物监测揭示了其在新西兰果园中对选择压力的适应性 | Hemara, L. M. | N/A | Genomic biosurveillance of the kiwifruit pathogen Pseudomonas syringae pv. actinidiae biovar 3 reveals adaptation to selective pressures in New Zealand orchards | |
| 估计并纠正单细胞RNA测序数据中的索引跳跃误分配 | Miao, L. | N/A | Estimating and correcting index hopping misassignments in single-cell RNA-seq data | |
| 5-氟尿嘧啶处理下人细胞培养中RNA修饰的时间定位 | Berg, M. | N/A | Temporal placement of RNA modifications under 5-fluorouracil treatment in human cell culture | |
| 四个结构区域的流动性驱动植物LPOR的同工型特异性 | Gabruk, M. | N/A | Mobility of Four Structural Regions Drives Isoform-Specific Properties of Plant LPOR | |
| 发育中的哺乳动物视网膜中机械性能的尺度不变性 | Shelton, E. R. | N/A | Scale invariance of mechanical properties in the developing mammalian retina | |
| 通过信号分解和多尺度注意力克服分辨率增强Hi-C数据中的人工结构 | Li, Q. | N/A | Overcoming artificial structures in resolution-enhanced Hi-C data by signal decomposition and multi-scale attention | |
| 优化神经诱导中的信息传递限制了海鞘胚胎的细胞表面接触 | Bettoni, R. | N/A | Optimizing information transmission in neural induction constrains cell surface contacts of ascidian embryos | |
| 通过聚合物建模探索早衰症中的核纤层结构与解离 | Hameed, H. A. | N/A | Exploring Nuclear Lamina Structure and Lamin Dissociation in Progeria through Polymer Modeling | |
| PolSpec：基于偏振的光谱分类检测方法 | Liu, H. | N/A | PolSpec: polarisation-based detection for spectral classification of optical signals | |
| 结构鉴定出RyR1的RY12域为ADP传感器，并作为恶性高热治疗药物丹曲林的目标 | Kim, K. | N/A | Structural identification of the RY12 domain of RyR1 as an ADP sensor and the target of the malignant hyperthermia therapeutic dantrolene | |
| 3D-UHU-TU：健康尿路上皮环境中的三维膀胱癌模型 | Murray, B. O. | N/A | 3D-UHU-TU: A Three-Dimensional Bladder Cancer Model in a Healthy Urothelial Environment | |
| 线粒体功能障碍与内质网应激在人神经母细胞瘤SH-SY5Y细胞中CB1受体拮抗剂诱导的细胞凋亡中的作用 | Mori, K. | N/A | Mitochondrial Dysfunction and ER Stress in CB1 Receptor Antagonist-Induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells | |
| 基于成像质谱流式技术引导的多模态质谱成像的超分辨率单细胞空间代谢组学 | Ozturk, E. | N/A | Super Resolved Single-Cell Spatial Metabolomics from Multimodal Mass Spectrometry Imaging guided by Imaging Mass Cytometry | |
| 首次记录入侵的黄蜂（Vespa velutina nigrithorax Buysson, 1905）和雕刻切叶蜂（Megachile sculpturalis Smith, 1853）在斯洛伐克的出现（膜翅目：胡蜂科和切叶蜂科） | Purkart, A. | N/A | First records of invasive Vespa velutina nigrithorax Buysson, 1905 (Hymenoptera: Vespidae) and Megachile sculpturalis Smith, 1853 (Hymenoptera: Megachilidae) in Slovakia | |
| AEA对TAT处理的人星形胶质细胞的拮抗活性识别出炎症衰老通路 | Duraikannu, D. | N/A | Antagonistic activity of AEA on TAT treated Human Astrocytes identify Inflammaging pathways | |
| RBP4作为孤儿DR6的拮抗配体发挥功能 | Kim, T. | N/A | RBP4 functions as an antagonistic ligand of orphan DR6 | |
| 寄生虫物种多样性的维持：时空生态位分区和聚集促进物种共存 | Ramesh, A. | N/A | Maintenance of parasite species diversity: Spatiotemporal niche partitioning and aggregation facilitate species coexistence | |
| 真菌孢子季节在美国因气候变化而提前了二十年 | Wu, R. | N/A | Fungal spore seasons advanced across the US over two decades of climate change | |
| 全球范围内对敌害释放假说的检验揭示了本地植物和外来植物在食草行为上的相似模式 | Galman, A. | N/A | Global test of the enemy release hypothesis reveals similar patterns of herbivory across native and non-native plants | |
| 利用大规模层次聚类分析表观基因组间的统计关系 | Kim, A. | N/A | Statistical relationships across epigenomes using large-scale hierarchical clustering | |
| 单细胞分辨率DESI质谱成像通过10倍样品扩展 | Xie, C. | N/A | Single-Cell Resolution DESI Mass Spectrometry Imaging through 10-Fold Sample Expansion | |
| T细胞受体多样性、癌症与性别：来自30,000个TCRβ库的洞察 | Zahid, H. J. | N/A | T Cell Receptor Diversity, Cancer and Sex: Insights from 30,000 TCRβ Repertoires | |
| WRAD核心扰动损害了DNA复制的保真度，促进了胰腺癌中的免疫编辑 | Citron, F. | N/A | WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer | |
| 通过FBXW11和CTNNB1热点突变的互斥激活Wnt/β-catenin信号传导驱动唾液腺基底细胞腺瘤的发生 | Wong, K. | N/A | Activation of Wnt/β-catenin signalling by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary gland basal cell adenoma | |
| 建立和分子表征源自原发性中枢神经系统淋巴瘤患者的类器官 | Li, S. | N/A | Establishment and Molecular Characterization of Patient-Derived Organoids for Primary Central Nervous System Lymphoma | |
| EFP分析器：一款快速、准确且易于教学的程序，用于分析由诱导多能干细胞衍生心肌细胞产生的外场电位 | Patel, N. P. | N/A | EFP Analyzer: A fast, accurate, and easy-to-teach program for analyzing Extracellular Field Potentials from iPSC-derived cardiomyocytes | |
| hsa-miR-9-5p 在早发型子痫前期合体滋养层来源的细胞外囊泡中高表达，损害了脑微血管内皮细胞的促血管生成能力。 | Logenthiran, P. V. | N/A | hsa-miR-9-5p highly expressed in syncytiotrophoblast-derived extracellular vesicles from early-onset preeclampsia impairs cerebral microvascular endothelial cell pro-angiogenic capacity | |
| T细胞表位图谱揭示了SARS-CoV-2蛋白质组中进化保守区域具有免疫优势。 | Bozkus, C. C. | N/A | T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome. | |
| DNA复制和修复机制之间的冲突会促进革兰氏阳性细菌的细胞死亡。 | Gaimster, H. | N/A | Conflicts between the DNA replication and repair machineries promote cell death in Gram-positive bacteria | |
| 毒力调节并增强B群链球菌中的CRISPR-Cas9免疫 | Pastuszka, A. | N/A | Virulence regulates and boosts CRISPR-Cas9 immunity in Group B Streptococcus | |
| FtsK 启动了在无 FtsZ 的沙眼衣原体中组装独特的分裂体复合物 | Harpring, M. | N/A | FtsK Initiates the Assembly of a Unique Divisome Complex in the FtsZ-less Chlamydia trachomatis | |
| SARS-CoV-2在动物园老虎、狮子和鬣狗体内的种群扩张、多样化和适应 | Bashor, L. | N/A | SARS-CoV-2 within-host population expansion, diversification and adaptation in zoo tigers, lions and hyenas | |
| 通过完整组装揭示了不同小鼠亚种间端粒和着丝粒的结构多样性 | Adams, D. | N/A | The structural diversity of telomeres and centromeres across mouse subspecies revealed by complete assemblies | |
| 双工PCR检测法用于确定肩突硬蜱（蜱螨目：硬蜱科）的性别及交配状态，该蜱是莱姆病病原体的传播媒介。 | Ronai, I. | N/A | Duplex PCR assay to determine sex and mating status of Ixodes scapularis (Acari: Ixodidae), vector of the Lyme disease pathogen | |
| 去泛素化酶Rpn11作为一种变构泛素传感器，促进26S蛋白酶体与底物的结合。 | Htet, Z. M. | N/A | The deubiquitinase Rpn11 functions as an allosteric ubiquitin sensor to promote substrate engagement by the 26S proteasome | |
| 多花黄精根氟代聚磷酸-糖苷（NU2）通过靶向DNA拓扑异构酶I抑制多重耐药细菌和单细胞寄生虫 | CHAKRABORTY, A. K. | N/A | Suregada multiflora Root Fluro-PolyPhosphate-Glycoside (NU2) inhibits MDR Bacteria and Unicellular Parasites Targeting DNA Topoisomerase I | |
| 拓扑重排激活了HerA-DUF抗噬菌体防御系统 | Rish, A. D. | N/A | Topological rearrangements activate the HerA-DUF anti-phage defense system | |
| 利用光控开关鞘氨醇实现鞘脂生物合成的光学调控 | Kol, M. | N/A | Optical control of sphingolipid biosynthesis using photoswitchable sphingosines | |
| 从绿藻衣藻中高效分泌一种塑料降解酶 | Molino, J. V. D. | N/A | Efficient secretion of a plastic degrading enzyme from the green algae Chlamydomonas reinhardtii | |
| 利用纳米抗体与抗原相互作用调控铁氧还蛋白电子传递 | Truong, A. | N/A | Regulating ferredoxin electron transfer using nanobody and antigen interactions | |
| 基于CRISPRi的双功能逻辑门 | Yao, Z. | N/A | Dual-function logic gates based on CRISPRi | |
| 阐明异黄酮合酶介导的酵母蛋白质-蛋白质相互作用在代谢中的作用 | Liu, C. | N/A | Elucidating the metabolic roles of isoflavone synthase-mediated protein-protein interactions in yeast | |
| 用于单细胞分析的基因编码荧光条形码 | Lu, X. | N/A | Genetically-Encoded Fluorescence Barcodes for Single-Cell Analysis | |
| 将邻近标记酶展示于细胞外囊泡表面用于表面组及靶细胞的定位 | ZHENG, W. | N/A | Surface display of proximity labeling enzymes on extracellular vesicles for surfaceome and target cell mapping | |
| I型干扰素诱导肝细胞中的GBPs和溶酶体防御，以控制疟疾 | Marques-da-Silva, C. | N/A | Type-I IFNs induce GBPs and lysosomal defense in hepatocytes to control malaria | |
| 构建用于研究HIV-1复制及甲基苯丙胺影响的巨噬细胞嗜性亚型C HIV-1-mGreenLantern报告病毒 | Mofed, D. | N/A | Construction of a macrophage-tropic subtype C HIV-1-mGreenLantern reporter virus for studies on HIV-1 rep-lication and the impact of methamphetamine | |
| 脱氮微生物群落中协同作用的产生与破坏 | Carr, A. V. | N/A | Emergence and disruption of cooperativity in a denitrifying microbial community | |
| 非芳香化酶依赖的雌激素生成：Wood-Ljungdahl途径可能对生物圈中雌激素的出现有所贡献。 | Wang, P.-H. | N/A | Aromatase-independent estrogenesis: Wood-Ljungdahl pathway likely contributed to the emergence of estrogens in the biosphere | |
| 在土壤细菌向叶际过渡的早期阶段，确定性定殖现象便已出现，并受到植物与微生物相互作用的影响。 | Mayer, T. | N/A | Deterministic colonization arises early during the transition of soil bacteria to the phyllosphere and is shaped by plant-microbe interactions. | |
| 共生菌和致病菌附着于肠上皮细胞的肠道定殖动力学 | Rivera, D. E. | N/A | Dynamics of gut colonization by commensal and pathogenic bacteria that adhere to the intestinal epithelium | |
| 螺原体共生体减少宿主脂质合成及类Stomoxyn肽有助于舌蝇Glossina fuscipes抵抗锥虫 | Awuoche, E. O. | N/A | Spiroplasma endosymbiont reduction of host lipid synthesis and Stomoxyn-like peptide contribute to trypanosome resistance in the tsetse fly Glossina fuscipes | |
| 利用新型遗传方法进行端粒酶RNA的转运 | Kirk, K. E. | N/A | Trafficking of the Telomerase RNA using a Novel Genetic Approach | |
| 脑膜炎奈瑟菌B群荚膜多糖合成启动子的调控由HTH_XRE家族转录因子进行 | Sofowora, I. | N/A | Regulation of the Promoter for Capsular Polysaccharide Synthesis in Neisseria Meningitidis Serogroup B by HTH_XRE Family Transcription Factor | |
| TFAM作为UVC诱导的线粒体DNA损伤的传感器 | King, D. E. | N/A | TFAM as a sensor of UVC-induced mitochondrial DNA damage | |
| 融合前稳定型疱疹病毒gB三聚体的计算设计 | McCallum, M. | N/A | Computational design of prefusion-stabilized Herpesvirus gB trimers | |
| 植物中的铁与氧化还原感应：拟南芥BRUTUS和BRUTUS-LIKE2蛋白的蚯蚓血红蛋白样结构域特性 | Pullin, J. | N/A | Iron and redox sensing in plants: properties of the hemerythrin-like domains of Arabidopsis BRUTUS and BRUTUS-LIKE2 proteins | |
| 机器学习辅助定向进化的多样化组合景观评估 | Li, F.-Z. | N/A | Evaluation of Machine Learning-Assisted Directed Evolution Across Diverse Combinatorial Landscapes | |
| 一种跨动物和环境的普遍海马记忆编码 | Wirtshafter, H. S. | N/A | A universal hippocampal memory code across animals and environments | |
| GABA能神经元可以促进皮层扩散性去极化的传播：在小鼠新皮质切片中的实验以及一种新的神经场计算模型 | Baspinar, E. | N/A | GABAergic neurons can facilitate the propagation of cortical spreading depolarization: experiments in mouse neocortical slices and a novel neural field computational model | |
| 皮质去甲肾上腺素-星形胶质细胞信号在介导习得行为中起关键作用 | Drummond, G. T. | N/A | Cortical norepinephrine-astrocyte signaling critically mediates learned behavior | |
| 针对与严重儿童癫痫和早逝相关的胎儿期富集钾通道的基因治疗 | Golinski, S. | N/A | Gene therapy for targeting a prenatally enriched potassium channel associated with severe childhood epilepsy and premature death | |
| 大规模突触成像揭示了视觉皮层神经元的突触输入结构，无需反向传播的动作电位 | Kondo, S. | N/A | Synaptic input architecture of visual cortical neurons revealed by large-scale synapse imaging without backpropagating action potentials | |
| 精神分裂症和健康个体在深部脑形态和不对称性方面存在性别差异：ENIGMA-精神分裂症工作组的元分析 | Cimmino, D. | N/A | Sex differences in deep brain shape and asymmetry persist across schizophrenia and healthy individuals: A meta-analysis from the ENIGMA-Schizophrenia Working Group | |
| 树突图谱揭示纹状体D1/D2神经元形态的空间组织 | Park, C. S. | N/A | Dendritome Mapping Unveils Spatial Organization of Striatal D1/D2-Neuron Morphology | |
| TRAIL诱导caspase依赖性的网格蛋白介导的内吞作用机器特定组分的切割 | Lawrence, D. A. | N/A | TRAIL induces caspase-dependent cleavage of specific components of the clathrin-mediated endocytosis machinery | |
| # BioRxiv 2024-10-23 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 脑岛和颞上沟在社会决策中对人际内疚感和责任感的贡献 | Gaedeke, M. | N/A | Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions | |
| 图像平衡是一种自下而上的神经美学属性，介导注意力和眼球运动。一个原始的视觉操作系统解释了平衡的属性，以及一种基本的视觉组织世界的方式。 | Corwin, D. M. | N/A | Pictorial balance is a bottom-up neuro-aesthetic property mediating attention and eye movements. A primitive visual operating system explains the property of balance and a primary visual way of organizing the world. | |
| 清醒小鼠背侧下丘的噪声神经元群有效地编码声音定位 | Boffi, J. C. | N/A | Noisy neuronal populations effectively encode sound localization in the dorsal inferior colliculus of awake mice | |
| 多巴胺神经元在果蝇的嗅觉记忆中具有不同的、急性的功能，这些功能驱动着吸引和厌恶行为。 | Mohammad, F. | N/A | Dopamine neurons that inform Drosophila olfactory memory have distinct, acute functions driving attraction and aversion | |
| 为什么棕色的鬼魂在夜晚鸣叫 | Oboti, L. | N/A | Why the brown ghost chirps at night | |
| 通过过度产生cMYC蛋白在TP53和RB1缺失的肺神经内分泌细胞中形成恶性转移性小细胞肺癌，这些细胞源自人类胚胎干细胞 | Chen, H. | N/A | FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS | |
| 面向界面的分子生成框架用于蛋白质-蛋白质相互作用调节剂 | Wang, J. | N/A | Interface-aware molecular generative framework for protein-protein interaction modulators | |
| Rab10通过维持钙稳态和蛋白质合成来调节神经肽的释放。 | Dong, J. | N/A | Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis | |
| 简单寄生虫生命周期中的复杂相互作用塑造了其毒力的进化 | Silva, L. M. | N/A | Complex interactions in the life cycle of a simple parasite shape the evolution of virulence | |
| 在双亲群体中，从噪声低覆盖度测序数据中快速准确地进行基因型填补 | Triay, C. | N/A | Fast and accurate imputation of genotypes from noisy low-coverage sequencing data in bi-parental populations | |
| 蛋白质凝聚物中分子相互作用强度的光学表征 | Beck, T. | N/A | Optical characterization of molecular interaction strength in protein condensates | |
| 植物物种间的重复全球适应 | Nocchi, G. | N/A | Repeated global adaptation across plant species | |
| 使用MEG测量的人类听觉皮层适应寿命的半球差异 | Dar, A. H. | N/A | Hemispheric difference of adaptation lifetime in human auditory cortex measured with MEG | |
| tRNA基因表达的适应性损失导致海洋蓝藻Synechococcus对噬菌体的抗性 | Zborowsky, S. | N/A | Adaptive loss of tRNA gene expression leads to phage resistance in a marine Synechococcus cyanobacterium | |
| 定量蛋白质组学鉴定出在低级别浆液性卵巢癌中保守的蛋白质及粘蛋白-16的调控改变 | Tarney, C. M. | N/A | Quantitative Proteomics Identifies Conserved Proteins and Altered Regulation of Mucin-16 in Low Grade Serous Ovarian Cancers | |
| 基于微管重叠区域中的马达蛋白的染色体排列模型 | Sigmund, I. | N/A | Model for chromosome congression based on motor proteins in microtubule overlaps | |
| ATAC与RNA测序的整合揭示了经典和非经典斑马鱼成骨细胞中的染色质和转录组特征，并指出了entpd5a调控的机制 | Petratou, K. | N/A | Integration of ATAC and RNA-sequencing identifies chromatin and transcriptomic signatures in classical and non-classical zebrafish osteoblasts and indicates mechanisms of entpd5a regulation | |
| 原癌基因Bcl3的磷酸化诱导的灵活性调节NF-κB p52同源二聚体的转录激活 | Pan, W. | N/A | Phosphorylation-induced flexibility of proto-oncogenic Bcl3 regulates transcriptional activation by NF-κB p52 homodimer | |
| 探究配体介导的Pre-miR21构象动力学：基于机器学习的增强采样研究 | Aureli, S. | N/A | Investigating Ligand-Mediated Conformational Dynamics of Pre-miR21: A Machine-Learning-Aided Enhanced Sampling Study | |
| 埃及伊蚊VLG-1基因在体内对Vago基因的抗病毒特性提出了挑战 | Couderc, E. | N/A | Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes in vivo | |
| 埃及伊蚊VLG-1基因质疑了Vago基因在体内具有抗病毒特性的假设 | Couderc, E. | N/A | Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes in vivo | |
| 一种能够穿过血脑屏障的肽-神经降压素偶联物，在小鼠癫痫持续状态后诱导了与抗惊厥、神经保护和抗炎特性相关的药理性低体温。 | Ferhat, L. | N/A | A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice | |
| 纳米孔直接RNA测序的解复用和条形码特异性自适应采样 | van der Toorn, W. | N/A | Demultiplexing and barcode-specific adaptive sampling for nanopore direct RNA sequencing | |
| 用于 ArtiaX 的相机路径、建模和图像处理工具 | Ermel, U. H. | N/A | Camera Paths, Modeling, and Image Processing Tools for ArtiaX | |
| 视网膜辨别力对自然场景的适应 | Ding, X. | N/A | Adaptation of retinal discriminability to natural scenes | |
| ReAct项目：分析来自23个不同实验室的数据，以表征在两组活动水平命题下DNA的恢复情况 | Gill, P. | N/A | The ReAct project: Analysis of data from 23 different laboratories to characterise DNA recovery given two sets of activity level propositions | |
| 囊杆菌素非靶向分析揭示了其在真核生物中良好的安全性、超氧阴离子还原能力及SCARB1抑制作用 | Risch, T. | N/A | Cystobactamid off-target profiling reveals favorable safety, superoxide reduction, and SCARB1 inhibition in eukaryotes | |
| LIFERING是一种E3泛素连接酶，能够泛素化酰基辅酶A脱氢酶样蛋白IBR3，并在DNA损伤时协调细胞增殖与死亡。 | Kallai, B. | N/A | LIFERING, an E3 ligase ubiquitinates the acyl-CoA dehydrogenase-like protein IBR3, and coordinates cell proliferation and death upon DNA damage | |
| 靶向乙酰转移酶NAT10可纠正人类额颞叶痴呆神经元的病理，并延长体内果蝇tau病模型的寿命 | Paonessa, F. | N/A | Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal dementia neurons and extends lifespan in an in vivo Drosophila tauopathy model | |
| 针对乙酰转移酶NAT10进行靶向治疗，可以纠正人类额颞叶痴呆神经元的病理变化，并在果蝇体内tau蛋白病变的模型中延长寿命。 | Paonessa, F. | N/A | Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal dementia neurons and extends lifespan in an in vivo Drosophila tauopathy model | |
| 多色荧光活细胞成像在盘基网柄菌中的应用 | Hashimura, H. | N/A | Multi-color fluorescence live-cell imaging in Dictyostelium discoideum | |
| 线粒体分裂调控皮质中星形胶质细胞的形态发生与组织结构 | Salazar, M. P. R. | N/A | Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex | |
| 大黄素增强的人脐带间充质干细胞外泌体通过靶向炎症和细胞焦亡缓解急性胰腺炎 | Liu, X. | N/A | Emodin-Enhanced hUC-MSC Extracellular Vesicles Alleviate Acute Pancreatitis by Targeting Inflammation and Pyroptosis | |
| 生长中的巨噬细胞通过胞饮作用调节高水平的溶质通量 | Tebeje, B. M. | N/A | Growing Macrophages Regulate High Rates of Solute Flux by Pinocytosis | |
| 人类卫星3号DNA编码了百万碱基尺度的转录因子结合平台 | Franklin, J. M. | N/A | Human Satellite 3 DNA encodes megabase-scale transcription factor binding platforms | |
| SpotMAX：一种用于多维自动斑点检测和定量的通用框架 | Padovani, F. | N/A | SpotMAX: a generalist framework for multi-dimensional automatic spot detection and quantification | |
| 对西丘两具早期铜石并用时代个体的古DNA分析 | Dogu, A. | N/A | Ancient DNA analyses of two Early Chalcolithic Individuals from the West Mound | |
| 年龄依赖性的神经3D染色质互作组的成熟与在丰富环境中的再生 | Gancedo-Verdejo, J. | N/A | Age-Dependent Maturation and Rejuvenation of the Neural 3D Chromatin Interactome in Enriched Environments | |
| 胰腺胰岛α细胞通过调节相邻β细胞的微管稳定性来调节胰岛素分泌，并在小鼠和人类胰岛中诱导功能异质性。 | Ho, K.-H. | N/A | Pancreatic islet alpha cells regulate microtubule stability in neighboring beta cells to tune insulin secretion and induce functional heterogeneity in individual mouse and human islets | |
| 使用卷积神经网络预测塑料降解酶的框架 | Hasnat, S. | N/A | A Framework for Accurate Prediction of Plastic-Degrading Enzymes using Convolutional Neural Networks | |
| 将个人评估和小团体评估结合作为教学策略的好处 | Arini, G. S. | N/A | Benefits of combining individual and small group assessments as an instructional strategy | |
| NHGRI-EBI GWAS目录：可重用性、可持续性和多样性的标准 | Cerezo, M. | N/A | The NHGRI-EBI GWAS Catalog: standards for reusability, sustainability and diversity | |
| 在大西洋奴隶贸易期间和之后，圣多美岛上的嵌套混血现象 | Ciccarella, M. | N/A | Nested admixture during and after the Trans-Atlantic Slave Trade on the island of Sao Tome | |
| 人类转录组中RNA修饰的综合调查 | Mulroney, L. | N/A | A comprehensive survey of RNA modifications in a human transcriptome | |
| 通过奇异积分算子模拟昆虫外骨骼中的率无关阻尼 | Pons, A. | N/A | Modelling rate-independent damping in insect exoskeleta via singular integral operators | |
| 对T细胞受体进行远程力调制揭示了CD4+ T细胞激活的NFAT阈值 | Clarke, J. J. | N/A | Remote force modulation of the T-cell receptor reveals an NFAT-threshold for CD4+ T cell activation | |
| 阿拉斯加产红藻、德瓦拉藻和掌状藻的培养方案 | Umanzor, S. | N/A | Cultivation protocols the rhodophytes, Devaleraea mollis and Palmaria hecatensis from Alaska | |
| BoundaryStats：一个用于计算边界重叠统计的R包 | Luo, A. R. | N/A | BoundaryStats: An R package to calculate boundary overlap statistics | |
| 醛固酮分泌腺瘤中的MCOLN3体细胞突变导致原发性醛固酮增多症。 | van Rooyen, D. | N/A | Somatic Mutations in MCOLN3 in Aldosterone-Producing Adenomas cause Primary Aldosteronism. | |
| 基于肽的复合凝聚物通过阳离子-π相互作用稳定用于细胞工程 | Sun, Y. | N/A | Peptide-Based Complex Coacervates Stabilized by Cation-π Interactions for Cell Engineering | |
| Toden-E：基于拓扑和密度的集成聚类方法，用于利用PAG网络和LLM在功能基因组学中开发超级PAG | Li, Q. | N/A | Toden-E: Topology-Based and Density-Based Ensembled Clustering for the Development of Super-PAG in Functional Genomics using PAG Network and LLM | |
| 通过转录组学剖析乳腺癌异质性：揭示多样致病因素以发现常见生物标志物 | Hossain, M. U. | N/A | Dissecting Breast Cancer Heterogeneity Through Transcriptomics Insights of Diverse Etiological Factors for Common Biomarker Discovery | |
| TCGA泛癌中位点特异性重复元件的失调 | Wang, C. | N/A | Dysregulation of locus-specific repetitive elements in TCGA pan-cancers | |
| LIV结合蛋白中不同构象及配体逃逸路径的相对稳定性：分子动力学模拟研究 | Das, J. | N/A | Relative stability of different conformations and pathways of ligand escape in LIV-binding protein: A molecular dynamics simulation study | |
| 全反式维甲酸介导的ADAR1降解与PD-1阻断协同作用抑制胰腺癌 | Li, C.-F. | N/A | All-trans retinoic acid-mediated ADAR1 degradation synergizes with PD-1 blockade to suppress pancreatic cancer | |
| 中间普氏菌的蛋白酶interpain A促进人舌鳞状细胞癌细胞的增殖和迁移 | Chang, S.-M. | N/A | The protease interpain A of Prevotella intermedia promotes human OSCC cells proliferation and migration | |
| 二苯乙烯碘化物氯化物通过靶向MYCN诱导的线粒体改变，抑制MYCN扩增的神经母细胞瘤。 | Epp, S. | N/A | Diphenyleneiodonium chloride inhibits MYCN-amplified neuroblastoma by targeting MYCN induced mitochondrial alterations | |
| 岩藻多糖-铜纳米颗粒协同增强癌细胞铜死亡与免疫治疗 | Chen, H. | N/A | Fucoidan-Copper Nanoparticles to Potentiate Synergistic Cancer Cell Cuproptosis and Immunotherapy | |
| 从单一物种到群落：使用Feliplex进行微卫星扩增子测序以监测猫科动物 | Rana, D. | N/A | From single species to communities: microsatellite amplicon sequencing to monitor felids using Feliplex | |
| 稻田鸟类群落组成：收获阶段和周围植被的影响——来自阿格内博德韦帕农场的见解。 | Ibrahim, I. | N/A | Avifauna composition in Rice plantations: effects of Harvesting Stage and Surrounding Vegetation. Insights from Weppa Farm, Agenebode. | |
| Rag2Mol：基于检索增强生成的结构导向药物设计 | Zhang, P.-D. | N/A | Rag2Mol: Structure-based drug design based on Retrieval Augmented Generation | |
| 探究亨廷顿蛋白N17结构域的曲率感知能力 | Nanajkar, N. | N/A | Investigating the curvature sensing ability of Huntingtin's N17 domain | |
| 通过线粒体移植增强人胶质母细胞瘤中辐射诱导的活性氧生成 | Marshall, K. | N/A | Enhancing Radiation-induced Reactive Oxygen Species Generation Through Mitochondrial Transplantation in Human Glioblastoma | |
| 成纤维细胞分泌的lumican和biglycan通过旁分泌调节IFN-γ分泌的CD4+ T细胞，对过敏性接触性皮炎具有保护作用。 | Maiti, G. | N/A | Paracrine regulations of IFN-γ secreting CD4+ T cells by lumican and biglycan are protective in allergic contact dermatitis | |
| 核效应在决定密码子使用依赖性的人类基因表达中起着重要作用。 | Garg, R. | N/A | Nuclear effects play an important role in determining codon usage-dependent human gene expression | |
| 低秩全矩阵分解用于单细胞RNA-seq中的丢弃填补，并与下游应用的填补算法进行基准测试 | Huang, J. | N/A | Low-Rank Full Matrix Factorization for dropout imputation in single cell RNA-seq and benchmarking with imputation algorithms for downstream applications | |
| 突触小泡内吞缺陷是帕金森病和路易体痴呆中与GBA相关的认知功能障碍的基础 | Vidyadhara, D. J. | N/A | Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson's disease and Dementia with Lewy bodies | |
| 40 Hz感觉刺激增强阿尔茨海默病小鼠模型中导航时的CA3-CA1协调和前瞻性编码 | Paulson, A. L. | N/A | 40 Hz sensory stimulation enhances CA3-CA1 coordination and prospective coding during navigation in a mouse model of Alzheimer's disease | |
| 内侧延伸杏仁核Otp谷氨酸能神经元的性类固醇受体表达及性别差异 | Gonzalez-Alonso, A. | N/A | Expression of sex steroid receptors and sex differences of Otp glutamatergic neurons of the medial extended amygdala | |
| 触屏响应精度对探索/利用权衡敏感 | Mueller, D. | N/A | Touchscreen response precision is sensitive to the explore/exploit tradeoff | |
| 活细菌全细胞生物传感器的成像揭示了哺乳动物肠道炎症区域唾液酸的可利用性空间分布。 | Carreno, D. | N/A | Imaging of live bacterial whole-cell biosensors illuminates spatial sialic acid availability within the inflamed mammalian gut | |
| 使用变分自编码器设计极简大肠杆菌基因组 | Barnes, C. P. | N/A | Designing minimal E. coli genomes using variational autoencoders | |
| 通过改良的cDICE方法选择巨型单层囊泡（GUVs）的大小 | Chen, A. | N/A | Size Selection of Giant Unilamellar Vesicles (GUVs) via Modified cDICE Method | |
| 工作记忆中的干扰预期与跨空间尺度的θ和β振荡相关 | Jung, D. Y. | N/A | Distractor anticipation during working memory is associated with theta and beta oscillations across spatial scales | |
| 在面对模糊的感觉输入时，CA3/齿状回表征的排斥是由不同的内部信念驱动的。 | Guo, W. A. | N/A | Repulsion of CA3 / dentate gyrus representations is driven by distinct internal beliefs in the face of ambiguous sensory input | |
| 前扣带皮层中一种常见的目标维持机制，适用于信息和努力选择 | Gonzalez, V. V. | N/A | A common stay-on-goal mechanism in anterior cingulate cortex for information and effort choices | |
| 行走过程中经颅磁刺激对腿部轨迹的调节 | Bourgeois, H. | N/A | Modulation of leg trajectory by transcranial magnetic stimulation during walking | |
| 2型糖尿病重塑侧支循环并促进缺血性卒中后白细胞粘附 | Sato, Y. | N/A | Type 2 diabetes remodels collateral circulation and promotes leukocyte adhesion following ischemic stroke | |
| SC10X/U：一种用于非侵入性记录颈脊髓神经活动的高密度电极系统 | Mehra, P. | N/A | SC10X/U: A High-density Electrode System for Non-Invasive Recording of Neural Activity of the Cervical Spinal Cord | |
| 十二种磷酸模拟突变促使重组全长人类tau蛋白形成成对螺旋丝 | Lövestam, S. | N/A | Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments | |
| 在空间导航过程中对决策神经动力学的全皮层表征 | Haley, S. P. | N/A | Cortex-wide characterization of decision-making neural dynamics during spatial navigation | |
| 钠泄漏通道NALCN缺失对纹状体Drd2棘突投射神经元具有性别偏向效应 | Castell, L. | N/A | Sex-biased effect of sodium leak channel NALCN deletion in striatal Drd2 spiny projection neurons | |
| 在帕金森病rAAV6-α-Syn+PFFs诱导的大鼠模型中，全身给予可溶性TNF抑制剂XPro1595后缺乏神经保护作用 | Fredlund, F. | N/A | Lack of neuroprotection after systemic administration of the soluble TNF inhibitor XPro1595 in an rAAV6-α-Syn+PFFs-induced rat model for Parkinson's disease | |
| RPE特异性MCT2表达促进视网膜色素变性模型中的锥体细胞存活 | Chandler, L. C. | N/A | RPE-specific MCT2 expression promotes cone survival in models of retinitis pigmentosa | |
| YTHDF蛋白塑造了阿尔茨海默病的大脑基因特征 | Tasaki, S. | N/A | The YTHDF Proteins Shape the Brain Gene Signatures of Alzheimer's Disease | |
| Omega-3脂肪酸通过海马体中miRNAs的调控，使突触后密度蛋白恢复正常，并防止DEHP引起的学习记忆功能障碍。 | Ding, M. | N/A | Omega-3 fatty acid normalizes postsynaptic density proteins via miRNAs regulation in hippocampus and prevents DEHP-induced impairment of learning and memory in mice | |
| 通过ds-Tango揭示的果蝇求偶过程中趋同的嗅觉回路 | Fisher, J. D. | N/A | Convergent olfactory circuits for courtship in Drosophila revealed by ds-Tango | |
| 海马区尖波涟漪与新皮层慢振荡之间潜在的双向交互作用的地形图 | Swanson, R. A. | N/A | Topography of putative bidirectional interaction between hippocampal sharp wave ripples and neocortical slow oscillations | |
| 在大鼠内侧内嗅皮层中，癫痫持续状态后对CBD的GABA-A受体反应 | Henley, B. S. | N/A | A GABA-A receptor response to CBD following status epilepticus in the medial entorhinal cortex of the rat | |
| 效应器选择先于运动指定：来自运动计划中重复效应的证据 | Seegelke, C. | N/A | Effector selection precedes movement specification: evidence from repetition effects in motor planning | |
| 过量补充叶酸会降低雄性和雌性黑腹果蝇在缺氧24小时后的存活率。 | Gunnala, S. | N/A | Over supplementation of folic acid reduces survival 24 hours after hypoxia in male and female Drosophila melanogaster | |
| 多巴胺能、胆碱能和去甲肾上腺素能网络在帕金森病嗅觉减退中的作用 | Perot, J.-B. | N/A | The role of dopaminergic, cholinergic and noradrenergic networks in hyposmia in Parkinson's disease | |
| ALS相关的RNA结合蛋白通过调节REST来汇聚于UNC13A的转录 | Watanabe, Y. | N/A | ALS-associated RNA binding proteins converge on UNC13A transcription through regulation of REST | |
| 独特的运动控制和学习优化：自定节奏的运动学习实现了与过度训练不同的运动模式。 | Hayashi, T. | N/A | Distinct optimization of motor control and learning: Self-paced motor learning achieves different motor patterns from overtrained | |
| 解码人类大脑皮层和杏仁核中与心理创伤相关的转录组特征 | Hicks, E. M. | N/A | Decoding the transcriptomic signatures of psychological trauma in human cortex and amygdala | |
| 预防性使用米诺环素可减轻外周神经病变大鼠模型的痛觉过敏和抑郁样行为：一项初步研究 | Le, A. C. T. | N/A | Preemptive minocycline decreases allodynia and depressive-like behaviors in a peripheral neuropathy rat model: a preliminary study | |
| 单侧空间忽略中神经振荡相位同步的频率特异性半球偏侧化 | Okazaki, Y. O. | N/A | Frequency-specific hemispheric bias in phase entrainment of neural oscillations in unilateral spatial neglect | |
| SARS-CoV-2 KP.3.1.1和XEC通过NTD糖基化增强的免疫逃逸能力 | Liu, J. | N/A | Enhanced immune evasion of SARS-CoV-2 KP.3.1.1 and XEC through NTD glycosylation | |
| 近期地方性冠状病毒感染与更高水平的SARS-CoV-2交叉反应性Fc受体结合抗体相关 | Bean, D. J. | N/A | Recent Endemic Coronavirus Infection Associates With Higher SARS-CoV-2 Cross-Reactive Fc Receptor Binding Antibodies | |
| 重新激活的I型干扰素信号传导与COVID-19的年龄依赖性差异有关 | Petrov, L. | N/A | Rewired type I IFN signaling is linked to age-dependent differences in COVID-19 | |
| 通过利用互补防御系统增强嗜热链球菌的噬菌体抗性 | Leprince, A. | N/A | Strengthening Phage Resistance of Streptococcus thermophilus by Leveraging Complementary Defense Systems | |
| 免疫史对高致病性H5N1亚型2.3.4.4b病毒挑战的疾病严重程度有修饰作用 | Brigleb, P. H. | N/A | Immune History Modifies Disease Severity to HPAI H5N1 Clade 2.3.4.4b Viral Challenge | |
| 人巨细胞病毒（HCMV）的有效感染多重性取决于细胞20S蛋白酶体的活性。 | Cataldo, K. M. | N/A | The effective multiplicity of infection for HCMV depends on activity of the cellular 20S proteasome | |
| CABO-16S：一种综合了古菌、细菌、细胞器16S的数据库，用于环境样本中真核生物和原核生物扩增子分析 | Eitel, E. M. | N/A | CABO-16S : A Combined Archaea, Bacteria, Organelle 16S database for amplicon analysis of prokaryotes and eukaryotes in environmental samples | |
| 蒲桃（Syzygium cumini (L.) Skeels）具有耐热且选择性抗炭疽杆菌活性 | Kaur, R. | N/A | Syzygium cumini (L.) Skeels has Thermostable and Selective Anti-Bacillus anthracis Activity | |
| 比较分析Pseudoalteromonas tunicata生物膜发育的蛋白质组学揭示了一类独特的依赖Ca2+的粘附素 | Ali, S. | N/A | Comparative proteomics of biofilm development in Pseudoalteromonas tunicata discovers a distinct family of Ca2+-dependent adhesins | |
| 农业系统中的土壤性质影响微生物基因组特征 | Goodall, T. I. | N/A | Soil properties in agricultural systems affect microbial genomic traits | |
| 短杆菌肽S对不同培养复杂度下微生物生理的影响 | Shlakhter, O. | N/A | The impact of tropodithietic acid on microbial physiology under varying culture complexities | |
| 先前存在的H1N1免疫力可减少牛H5N1流感病毒引起的严重疾病 | Le Sage, V. | N/A | Pre-existing H1N1 immunity reduces severe disease with bovine H5N1 influenza virus | |
| 野生鸟类自然种群中与血孢子虫相关的嵌套RNA病毒的流行与多样性 | Esperanza, C. W. | N/A | Prevalence and Diversity of Haemosporidian-Associated Matryoshka RNA Viruses in a Natural Population of Wild Birds | |
| 无细胞重组酶集成布尔输出系统（CRIBOS） | Chen, J. | N/A | Cell-Free Recombinase Integrated Boolean Output System (CRIBOS) | |
| 通过下边缘区神经元周围网降解增强恐惧消退：青少年酒精暴露的调节作用 | Obray, J. D. | N/A | Enhanced Fear Extinction Through Infralimbic Perineuronal Net Digestion: The Modulatory Role of Adolescent Alcohol Exposure | |
| 内源性神经元DNA双链断裂并不足以驱动大脑老化和神经退行性变。 | Cohen, S. | N/A | Endogenous neuronal DNA double-strand breaks are not sufficient to drive brain aging and neurodegeneration | |
| 迷幻、睡眠和镇静状态的神经相关性支持意识的全局理论 | Dai, R. | N/A | Neural Correlates of Psychedelic, Sleep, and Sedated States Support Global Theories of Consciousness | |
| 利用MEG研究自闭症与非自闭症青少年视角采择的神经振荡基础 | Seymour, R. A. | N/A | The Neural Oscillatory Basis of Perspective-Taking in Autistic and Non-Autistic Adolescents using MEG | |
| 念珠菌属杀鱼菌感染中的异铁载体转运基因表达及类群特异性菌丝形成 | Gifford, H. | N/A | Xenosiderophore transporter gene expression and clade-specific filamentation in Candida auris killifish infection | |
| 高频并行进化的致病性鲍曼不动杆菌培养物证据 | Mclaughlin, J. | N/A | Evidence for high-frequency parallel evolution in virulent A. baumannii cultures | |
| 铜绿假单胞菌的烷基喹诺酮应答被粪肠球菌所抑制 | Fink, M. M. | N/A | Pseudomonas aeruginosa Alkyl Quinolone Response is dampened by Enterococcus faecalis | |
| 多代蛋白水解失活限制在微妙基因组低甲基化后 | Shmidov, E. | N/A | Multigenerational Proteolytic Inactivation of Restriction Upon Subtle Genomic Hypomethylation | |
| 自发α波段侧化通过调节皮层兴奋性延长视觉信息在表象记忆中的持续时间。 | Smith, P. J. C. | N/A | Spontaneous alpha-band lateralization extends persistence of visual information in iconic memory by modulating cortical excitability. | |
| # BioRxiv 2024-10-22 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 棒状细菌荧光假单胞菌SBW25的球形mreB缺失突变体的进化救援 | Yulo, P. R. | N/A | Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25 | |
| 在微型鱼类丹尼奥内拉·大脑中，催产素介导的社会偏好与社会强化奖励学习 | Penalva, A. | N/A | Oxytocin-mediated social preference and socially reinforced reward learning in the miniature fish Danionella cerebrum | |
| 循环连接通过解释消除机制促进遮挡物体的识别。 | Kang, B. | N/A | Recurrent connections facilitate occluded object recognition by explaining-away | |
| 果蝇母体和早期合子转录调控的演变 | Omura, C. | N/A | Evolution of maternal and early zygotic transcript regulation across Drosophila | |
| T细胞牵引力表现出依赖于刺激和细胞亚型的时序模式。 | Mustapha, F. | N/A | T Cell Traction Forces show temporal patterns which Depend on Stimulation and Cell Subtype | |
| 在注意力瞬盲期间评估工作记忆表征：一种比较建模方法 | Wang, S. | N/A | Evaluating Working Memory Representations during the Attentional Blink: A Comparative Modeling Approach | |
| HuR通过促进多嘧啶序列结合蛋白的结合，增强SARS-CoV-2非结构蛋白在基因组5'-UTR区域的翻译。 | Raheja, H. | N/A | HuR enhances SARS-CoV-2 non-structural protein translation through the genomic 5'-UTR, by promoting polypyrimidine tract-binding protein binding | |
| PPE25（Rv1787）-PE18（Rv1788）-PPE26（Rv1789）基因簇参与了结核分枝杆菌的免疫逃避。 | Mukku, R. P. | N/A | The PPE25 (Rv1787)-PE18 (Rv1788)-PPE26 (Rv1789) gene cluster is involved in immune evasion by Mycobacterium tuberculosis | |
| 自我评估的贝叶斯更新解释了社会支配和胜者-败者效应 | Perkes, A. | N/A | Bayesian updating for self-assessment explains social dominance and winner-loser effects | |
| 统一稀疏编码、预测编码和除法归一化 | Lian, Y. | N/A | Unifying sparse coding, predictive coding, and divisive normalization | |
| 由致病性减弱肺炎链球菌生物合成基因突变体引发的微侵袭及免疫反应 | Weight, C. M. | N/A | Microinvasion and immunity elicited by disease-attenuated pneumococcal biosynthesis gene mutants | |
| 有性生殖种群中有益、有害和中性突变对适应性影响的整合模型 | Irlam, G. | N/A | An integrated model of the effects on fitness of beneficial, deleterious, and neutral mutations in sexual populations | |
| 雄性豆娘的Opsin基因表达可塑性和光谱敏感性可能介导了对雌性颜色形态的检测。 | Roberts, N. S. | N/A | Opsin gene expression plasticity and spectral sensitivity in male damselflies could mediate female colour morph detection | |
| 翻译：光合作用对翻译机制的需求促使植物细胞器中保留了冗余的tRNA代谢 | DeTar, R. A. | N/A | Photosynthetic demands on translational machinery drive retention of redundant tRNA metabolism in plant organelles | |
| 高粱1（Sorghum bicolor）气生根分泌的粘液可作为固氮菌的宿主，这些固氮菌能为植物提供大量氮素。 | Venado, R. E. | N/A | Mucilage Produced by Sorghum 1 (Sorghum bicolor) Aerial Roots Hosts Diazotrophs that Provide Significant Amounts of Nitrogen to the Plant | |
| 鉴定用于改进狂犬病病毒监测的支系特异性单核苷酸多态性 | Kumar, A. | N/A | Identification of clade-defining single nucleotide polymorphisms for improved rabies virus surveillance | |
| 多模态子空间独立向量分析有效地捕捉了大脑结构与功能之间的潜在关系。 | Li, X. | N/A | Multimodal subspace independent vector analysis effectively captures the latent relationships between brain structure and function | |
| 在感染早期，一个具有转录活性的脂质囊泡包裹着注入的Chimalliviridae病毒基因组。 | Armbruster, E. | N/A | A transcriptionally active lipid vesicle encloses theinjected Chimalliviridae genome in early infection | |
| 人类大脑中电刺激的基因表达特征 | Chatterjee, S. | N/A | The gene expression signature of electrical stimulation in the human brain | |
| 通过HCN通道对NMDA放大进行输入特异性调控在鼠L2/3层锥体神经元中的作用 | Olah, V. J. | N/A | Input-specific gating of NMDA amplification via HCN channels in mouse L2/3 pyramidal neurons | |
| 活动依赖性的突触聚集在发育中的视网膜下丘脑系统中导致了眼特异性竞争的形成。 | Zhang, C. | N/A | Activity-dependent synapse clustering underlies eye-specific competition in the developing retinogeniculate system | |
| 短期社交隔离通过作用于下丘脑神经元，以性别和情境依赖的方式促进社交行为。 | Zhao, X. | N/A | Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent manner | |
| OCA-B促进干细胞样CD4+ T细胞的致病性成熟1和自身免疫性脱髓鞘 | Hughes, E. P. | N/A | OCA-B promotes pathogenic maturation 1 of stem-like CD4+ T cells and autoimmune demyelination | |
| 大豆品种北京成功结瘤所需的Sinorhizobium fredii USDA257的功能性VI型分泌系统 | Reyes-Perez, P. | N/A | The functional type VI secretion system of Sinorhizobium fredii USDA257 is required for a successful nodulation with Glycine max cv Pekin | |
| 基准测试单个降解蛋白质的鉴定，以探索古代蛋白质的最佳搜索策略 | Rodriguez Palomo, I. | N/A | Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins | |
| CAT Bridge：一种从多组学数据中高效挖掘基因-代谢物关联的工具包 | Yang, B. | N/A | CAT Bridge: an efficient toolkit for gene-metabolite association mining from multiomics data | |
| 斑马鱼活体成像显示，在早期发育过程中，只有大约2%而非50%的运动神经元通过凋亡死亡。 | Jia, H. | N/A | Zebrafish live imaging reveals only around 2% rather than 50% of motor neurons die through apoptosis during early development | |
| 系统性炎症加速了在过度表达人α-突触核蛋白的帕金森病大鼠模型中的神经退行性变 | Massaro Cenere, M. | N/A | Systemic inflammation accelerates neurodegeneration in a rat model of Parkinson's disease overexpressing human alpha-synuclein | |
| 通过单细胞RNA测序揭示肺腺癌中化疗诱导的免疫景观重塑与代谢重编程 | Huang, Y. | N/A | Unveiling chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing | |
| 心理压力通过miR-335-3p/Fos信号通路扰乱破骨细胞的骨代谢。 | Zhang, J. | N/A | Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast | |
| 化学诱导的衰老促使人类类小胶质细胞发生功能性变化 | Armanville, S. | N/A | Chemically induced senescence prompts functional changes in human microglia-like cells | |
| 聚类内分析揭示了组织特异性的突变模式 | Choudalakis, S. | N/A | Intra-clustering analysis reveals tissue-specific mutational patterns | |
| 噬菌体抗性与土壤细菌贪噬菌属（Variovorax sp.）的密度增加相关，并导致群落结构的改变。 | Castledine, M. | N/A | Phage resistance is associated with density increases in the soil bacterium Variovorax sp. and results in changes to community structure | |
| 通过CoVerage进行的计算机基因组监测预测并描述了SARS-CoV-2的关注变种 | Norwood, K. | N/A | In silico genomic surveillance by CoVerage predicts and characterizes SARS-CoV-2 Variants of Interest | |
| 利用自然生理状况标记揭示自然啮齿动物种群中轻度干旱条件的负面影响 | Keilani, H. S. | N/A | Negative impact of mild arid conditions in natural rodent populations revealed using markers of physiological condition in natura | |
| 社会老龄化可以保护群居灵长类动物免受传染病的影响。 | Siracusa, E. R. | N/A | Social ageing can protect against infectious disease in a group-living primate | |
| 利用7T MRI研究人脑皮层下区域的工作记忆更新过程 | Trutti, A. C. | N/A | Investigating working memory updating processes of the human subcortex using 7T MRI | |
| srahunter：一个用户友好的工具，用于加速和简化从NCBI SRA下载数据 | Bortoletto, E. | N/A | srahunter: a user-friendly tool to speed up and simplify data downloading from NCBI SRA | |
| 细菌裂解噬菌体生命周期的单细胞成像 | Wedd, C. | N/A | Single-cell imaging of the lytic phage life cycle in bacteria | |
| 通过亲代微生物组对后代行为、海马体内的DNA甲基化和基因表达进行胎儿编程 | Gustafson, K. L. | N/A | Fetal programming by the parental microbiome of offspring behavior, and DNA methylation and gene expression within the hippocampus | |
| 湖泊螺旋藻（蓝藻）的化学指纹揭示了局部分子适应性 | Roussel, T. | N/A | Limnospira (Cyanobacteria) chemical fingerprint reveals local molecular adaptation | |
| 无细胞实验揭示，HIV-1衣壳能够保护逆转录产物免受cGAS的影响。 | Scott, T. M. | N/A | Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS | |
| 增殖与分化之间的失衡是微小RNA缺陷型成松果体瘤发展的基础 | Fraire, C. R. | N/A | An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma | |
| 社会地位对非洲慈鲷后续求偶和交配活动的影响 | Martashvili, A. | N/A | Effects of social position on subsequent courtship and mating activity in an African cichlid | |
| 豌豆蚜的母体vGluT2与胚胎mGluR3信号传递系统控制着后代翅膀二型性 | Yuan, Y. | N/A | The maternal vGluT2 and embryonic mGluR3 signaling relay system controls offspring wing dimorphism in pea aphid | |
| 通过基于典型相关特征的广义最大熵进行细粒度细胞反卷积 | Kamm, J. | N/A | Fine-scale cellular deconvolution via generalized maximum entropy on canonical correlation features | |
| 先天性心脏缺陷在左侧与右侧鸟类心脏神经嵴消融后表现出差异。 | Solovieva, T. | N/A | Congenital heart defects differ following left versus right avian cardiac neural crest ablation | |
| 在高分辨率和准确性下，对听觉中脑的神经编码进行建模 | Drakopoulos, F. | N/A | Modeling neural coding in the auditory midbrain with high resolution and accuracy | |
| 通过调节RAS蛋白的棕榈酰化来控制其信号传导 | Zhu, J. | N/A | Control of the signaling of RAS proteins by modulating their palmitoylation | |
| 通过分离的大脑杏仁核回路控制先天嗅觉效价 | Howe, J. R. | N/A | Control of innate olfactory valence by segregated cortical amygdala circuits | |
| 断裂诱导复制被激活，以修复SETX缺陷细胞中与R-环相关的双链断裂 | Wu, T. | N/A | Break-induced replication is activated to repair R-loop-associated double-strand breaks in SETX-deficient cells | |
| 基因调控网络结构揭示了扰动效应的分布情况 | Aguirre, M. | N/A | Gene regulatory network structure informs the distribution of perturbation effects | |
| 禁用链接的概率视角：它们在植物-蜂鸟群落中的普遍性及其对群落稳健性的影响 | Duchenne, F. | N/A | A probabilistic view of forbidden links: their prevalence and their consequences for the robustness of plant-hummingbird communities | |
| 中央杏仁核中的效价和显著性编码 | Kong, M.-S. | N/A | Valence and Salience Encoding in the Central Amygdala | |
| 强化学习指导单细胞测序解码谱系和细胞命运决定 | Fu, Z. | N/A | Reinforcement learning guides single-cell sequencing in decoding lineage and cell fate decisions | |
| 生态竞争群落中的稳健共存 | Lechon-Alonso, P. | N/A | Robust coexistence in ecological competitive communities | |
| 跨界鱼类：评估跨界鱼类种群的过度捕捞脆弱性 | Gangal, M. | N/A | Unbounding fish: Assessing vulnerability to overexploitation for transboundary fish populations | |
| 选择强度在何时会增加进化拯救的概率？ | Xu, K. | N/A | When does the probability of evolutionary rescueincrease with the strength of selection? | |
| 通过极端瓶颈清除高度有害等位基因 | Stuart, O. P. | N/A | Purging of highly deleterious alleles through an extreme bottleneck | |
| MinD蛋白调控Haloferax volcanii中CetZ1的定位 | Brown, H. J. | N/A | MinD proteins regulate CetZ1 localisation in Haloferax volcanii | |
| 基于结构的RyR通道操作机制：钙离子和镁离子的作用 | Zahradnikova, A. | N/A | Structure-based mechanism of RyR channel operation by calcium and magnesium ions | |
| 基于新型扩增子的近全长基因组（NFLG）测序方法用于HIV-1 M组重组形式的研究 | Moscona, R. | N/A | Novel Amplicons based Method for Near-Full-Length Genome (NFLG) Sequencing of HIV-1 Group M Recombinant Forms | |
| 用于分子研究的新型复制能力报告表达裂谷热病毒 | Nogales, A. | N/A | Novel replication-competent reporter-expressing Rift Valley fever viruses for molecular studies | |
| 贝叶斯估计产生了反韦伯变异性 | Prat-Carrabin, A. | N/A | Bayesian estimation yields anti-Weber variability | |
| 大肠杆菌的系统发育通过blaTEM-1的可变表达驱动了阿莫西林-克拉维酸的耐药性。 | Matlock, W. | N/A | E. coli phylogeny drives co-amoxiclav resistance through variable expression of blaTEM-1 | |
| 通用高通量图像定量分析细胞内亚细胞结构动态及空间分布 | Grinstaff, M. | N/A | Universal high-throughput image quantification of subcellular structure dynamics and spatial distributions within cells | |
| 源自患者的结肠上皮类器官揭示了儿童溃疡性结肠炎中与脂质相关的代谢功能障碍 | Ojo, B. A. | N/A | Patient-derived colon epithelial organoids reveal lipid-related metabolic dysfunction in pediatric ulcerative colitis | |
| 肠道微生物群介导的脂质积累作为果蝇对蓝光毒性进化适应的驱动因素 | Takada, Y. | N/A | Gut microbiota-mediated lipid accumulation as a driver of evolutionary adaptation to blue light toxicity in Drosophila | |
| 按需定制的主客体结合自由能：一种自动化的OneOPES协议 | Febrer Martinez, P. | N/A | Host-Guest binding free energies a la carte: an automated OneOPES protocol | |
| 耳声发射而非行为测量可预测鸟类鸣叫专家的耳蜗神经频率调谐 | Karosas, D. M. | N/A | Otoacoustic emissions but not behavioral measurements predict cochlear-nerve frequency tuning in an avian vocal-communication specialist | |
| 北极迁徙草食动物的活动和皮质酮的昼夜和季节性节律：多方面的研究方法 | de Jong, M. E. | N/A | Diel and seasonal rhythmicity in activity and corticosterone in an Arctic migratory herbivore: A multifaceted approach | |
| CNValidatron，利用计算机视觉实现CNV调用的自动化验证 | Montalbano, S. | N/A | CNValidatron, automated validation of CNV calls using computer vision | |
| 利用相关性和机制性物种分布模型预测当前和未来环境及气候变化下的虫媒疾病风险：以英国西尼罗河病毒为例的研究。 | Withers, A. J. | N/A | Using correlative and mechanistic species distribution models to predict vector-borne disease risk for the current and future environmental and climatic change: a case study of West Nile Virus in the UK. | |
| 表面介导的噬菌体防御对细菌间拮抗作用产生了适应性权衡 | Tsai, C.-E. | N/A | Surface-mediated Bacteriophage Defense Incurs Fitness Tradeoffs for Interbacterial Antagonism | |
| 缺氧应激通过表观基因组和转录程序失调影响胶质瘤相关髓系细胞的功能。 | Dzwigonska, M. | N/A | Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs | |
| 定时喂食改善了脆性X综合征小鼠模型的行为结果并减少了炎症。 | Wang, H.-B. | N/A | Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome. | |
| 外周阿片受体拮抗作用可缓解芬太尼引起的心血管呼吸抑制，且无厌恶效应。 | Ruyle, B. | N/A | Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive effects | |
| miR-92a的靶标RBFOX2的过早上调劫持了PTBP剪接，并损害了皮层神经元的分化。 | Weissbach, S. | N/A | Premature upregulation of miR-92a's target RBFOX2 hijacks PTBP splicing and impairs cortical neuronal differentiation. | |
| 一份大规模的社区科学数据集揭示了北美红花植物中开花期延迟表型的趋同进化 | McKenzie, P. F. | N/A | A massive community-science dataset reveals convergent evolution of delayed flowering phenology in North American red-flowering plants | |
| AAV血清型转导嗅觉感觉神经元的比较分析 | Belfort, B. D. | N/A | Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons | |
| 肌动肌球蛋白收缩力是人多能干细胞诱导中胚层形成的有力抑制因素 | Fort, L. | N/A | Actomyosin Contractility is a Potent Suppressor of Mesoderm Induction by Human Pluripotent Stem Cells | |
| 温度诱导的膜转运驱动抗体向大脑的递送 | Du, F. | N/A | Temperature-induced membrane trafficking drives antibody delivery to the brain | |
| 化学定义的脂质饮食揭示了基因组最小细胞中脂质组重塑的多功能性 | Safronova, N. | N/A | Chemically defined lipid diets reveal the versatility of lipidome remodeling in genomically minimal cells | |
| DNA/多核糖体相分离与细胞宽度限制共同作用，将核区分离与大肠杆菌的细胞生长耦合起来。 | Papagiannakis, A. | N/A | DNA/polysome phase separation and cell width confinement couple nucleoid segregation to cell growth in Escherichia coli | |
| 多巴胺和皮质iPSC衍生的神经元在不同的帕金森病突变中显示出溶酶体和线粒体功能障碍的差异：这对蛋白质沉积与选择性细胞丢失的启示 | Chedid, J. | N/A | Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss | |
| 皮层阿尔法节律从自然场景背景中插值遮挡的运动 | Yeh, L.-C. | N/A | Cortical alpha rhythms interpolate occluded motion from natural scene context | |
| ReAct项目：分析来自23个不同实验室的数据，以描述在两组活动水平命题下的DNA恢复特征。 | Gill, P. | N/A | The ReAct project: Analysis of data from 23 differentlaboratories to characterise DNA recovery given twosets of activity level propositions | |
| 人脑视觉皮层中的行波：基于模型的MEG-EEG方法 | Grabot, L. | N/A | Traveling Waves in the Human Visual Cortex: an MEG-EEG Model-Based Approach | |
| 登革病毒复制型双链RNA通过RIG-I和MDA5的协同作用被识别，从而激活先天免疫反应。 | Ye, S. | N/A | Dengue virus replicative-form dsRNA is recognized by RIG-I and MDA5 cooperatively to activate innate immunity | |
| 新型抗体可检测原生生物病原体、细胞黏菌和植物中的核质O-岩藻糖 | Tiwari, M. | N/A | Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants | |
| 参数依赖性在可识别性中的应用：应用于Tauopathy网络建模参数化的FP-Fisher-KPP反应扩散方程 | Rahimabadi, A. | N/A | Parameter Dependence in Identifiability Applied to FP-Fisher-KPP Reaction-Diffusion Equations Parameterized for Tauopathy Network Modeling | |
| 部分相关性作为绘制人脑连接中功能-结构对应关系的工具 | Santucci, F. | N/A | Partial Correlation as a Tool for Mapping Functional-Structural Correspondence in Human Brain Connectivity | |
| 依赖于DNA的蛋白激酶抑制剂PI-103和Samotolisib增强CRISPR/Cas9在人类T细胞中的敲入效率 | Dzafo, E. | N/A | DNA-Dependent Protein Kinase Inhibitors PI-103 and Samotolisib Augment CRISPR/Cas9 Knockin Efficiency in Human T Cells | |
| 肺炎链球菌的周质和细胞壁中的磷壁酸 | Mai, N. | N/A | Teichoic acids in the periplasm and cell envelope of Streptococcus pneumoniae | |
| 放弃四极杆用于质谱碎裂分析：通过高分辨率离子迁移前体隔离实现1,000 Hz速度与100%离子利用率 | DeBord, D. | N/A | Abandoning the Quadrupole for Mass Spectrometry Fragmentation Analysis: Towards 1,000 Hz Speeds with 100% Ion Utilization Using High Resolution Ion Mobility Precursor Isolation | |
| 甘蔗黄叶病毒损害了甘蔗对新蚜虫媒介Melanaphis sorghi的转录组防御反应 | Pimenta, R. J. G. | N/A | Sugarcane yellow leaf virus impairs the transcriptomic defense responses of sugarcane to its new aphid vector Melanaphis sorghi | |
| 通过冷冻电镜断层成像技术可视化的AMPA受体支架复合物的原位结构与形貌 | Held, R. G. | N/A | In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET | |
| 生物科学博士在性别和种族/民族方面的出版差异显著模式 | Leap, K. | N/A | Distinct patterns of bioscience doctoral publication disparities by gender and race/ethnicity | |
| 大规模无意盲视实验揭示的身体检测反转效应 | Gandolfo, M. | N/A | A body detection inversion effect revealed by a large-scale inattentional blindness experiment | |
| DprA招募ComM，以促进革兰氏阴性菌在自然转化过程中进行重组 | Dalia, T. N. | N/A | DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria | |
| 猕猴V1和V2区中自然纹理的表征几何 | Pavuluri, A. | N/A | The representational geometry for naturalistic textures in macaque V1 and V2 | |
| 冬季围栏对欧洲芦苇鹿能量消耗和运动活动的影响 | Silovsky, V. | N/A | Impact of winter enclosures on energy expenditure and movement activity of european reed deer | |
| H2O2 重新利用植物的氧气感应机制来控制对氧化应激的转录反应。 | Akter, S. | N/A | H2O2 repurposes the plant oxygen-sensing machinery to control the transcriptional response to oxidative stress | |
| 苯并噁嗪介导的微生物群反馈增强了拟南芥的生长和防御能力。 | Stengele, K. | N/A | Benzoxazinoid-mediated microbiome feedbacks enhance Arabidopsis growth and defense | |
| 研究大麦的甲基组、其变异及其与基因组、转录组和表型变异的关联 | Kühl, M. A. | N/A | Investigating the barley methylome, its variation and association with genomic, transcriptomic, and phenotypic variation | |
| NUDIX水解酶特异性靶向肌醇焦磷酸，调控磷和铁稳态，并在拟南芥中调控防御基因的表达。 | Schneider, R. | N/A | NUDIX Hydrolases Target Specific Inositol Pyrophosphates and Regulate Phosphate and Iron Homeostasis, and the Expression of Defense Genes in Arabidopsis | |
| 一个基因组到蛋白质组的图谱绘制了控制蛋白质组多样性的自然变异，并预测了它们的适应性效应。 | Jakobson, C. M. | N/A | A genome-to-proteome atlas charts natural variants controlling proteome diversity and forecasts their fitness effects | |
| 评估从激酶-底物相互作用和磷酸蛋白质组学数据推断信号通路 | Garrido-Rodriguez, M. | N/A | Evaluating signaling pathway inference from kinase-substrate interactions and phosphoproteomics data | |
| 含GluN2B的NMDA受体在突触中的积累介导了BDNF-TrkB信号对突触可塑性和癫痫发生的影响。 | De Luca, P. | N/A | Synaptic accumulation of GluN2B-containing NMDA receptors mediates the effects of BDNF-TrkB signalling on synaptic plasticity and in epileptogenesis | |
| 奥杜瓦伊域表达下调线粒体途径：对人类大脑进化和幼态持续的意义 | Keeney, J. G. | N/A | Olduvai domain expression downregulates mitochondrial pathways: implications for human brain evolution and neoteny | |
| 转录组图谱识别出两种未被识别的室管膜瘤亚型及髓母细胞瘤中的新通路 | Arora, S. | N/A | Transcriptomic landscape identifies two unrecognized ependymoma subtypes and novel pathways in medulloblastoma | |
| 涉及长链非编码RNA MB3及驱动基因MYC和OTX2的电路通过调节HMGN5介导的TGF-β通路，抑制了3组髓母细胞瘤中的细胞凋亡。 | Grandioso, A. | N/A | A circuit involving the lncRNA MB3 and the driver genes MYC and OTX2 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5 | |
| SIM和CCS52A1控制根毛细胞的内复制和扩展 | Li, L. | N/A | SIM and CCS52A1 control root hair cell endoreplication and expansion | |
| 奥哈卡玉米（Zea mays）地方品种的气生根形成在成年阶段仍然持续，并且受土壤氮和环境湿度的影响较小。 | Wilker, J. | N/A | Aerial root formation in Oaxacan maize (Zea mays) landraces persists into the adult phase and is minimally affected by soil nitrogen and ambient humidity. | |
| COmapper：通过拟南芥长读长测序实现高分辨率减数分裂交叉图谱绘制 | Byun, D. | N/A | COmapper: High-resolution mapping of meiotic crossovers by long-read sequencing in Arabidopsis | |
| 利用生物弹射技术、多重CRISPR/Cas9编辑和Indel选择性PCR高效诱变玉米自交系 | Rai, M. N. | N/A | Efficient mutagenesis of maize inbreds using biolistics, multiplex CRISPR/Cas9 editing, and Indel-Selective PCR | |
| 外生菌根共生在蔷薇类植物谱系中独立进化，并通过趋同基因重复实现。 | van Beveren, F. | N/A | Ectomycorrhizal symbiosis evolved independently and by convergent gene duplication in rosid lineages | |
| 尖峰皮层及相连网络中的结构妥协 | Sahlas, E. | N/A | Structural compromise in spiking cortex and connected networks | |
| 根据重要性和难度对人类决策进行优先排序 | Aboalasaad, F. | N/A | Prioritization of decisions by importance and difficulty in human planning | |
| 使用MRIQC对未处理的人脑解剖、功能和扩散磁共振成像进行质量评估和控制 | Hagen, M. P. | N/A | Quality assessment and control of unprocessed anatomical, functional, and diffusion MRI of the human brain using MRIQC | |
| 视网膜神经节细胞的不同富集构成了所提出的核心神经退行性转录程序的基础 | Watkins, T. A. | N/A | Differential enrichment of retinal ganglion cells underlies proposed core neurodegenerative transcription programs | |
| 一个包含2,362份来自三大洲八所兽医教学医院的马粪微生物组的新数据集揭示了地理、品种和疾病的主导影响。 | McAdams, Z. L. | N/A | A novel dataset of 2,362 equine fecal microbiomes from eight veterinary teaching hospital on three continents reveals dominant effects of geography, breed, and disease | |
| 新生RNA标记化合物5-乙炔基尿苷（EU）在海葵Nematostella vectensis的DNA中整合。 | Kjosavik, M. A. | N/A | The nascent RNA labelling compound 5-ethynyl uridine (EU) integrates into DNA in the sea anemone Nematostella vectensis | |
| 预测肽结合特异性中单个残基效应的计算方法的互补评估 | Ayyildiz, M. | N/A | Complementary evaluation of computational methods for predicting single residue effects on peptide binding specificities | |
| 仔细审查脂质利用会破坏两性霉素B在利什曼原虫杜氏临床分离株中的反应性 | Pradhan, S. | N/A | Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani | |
| 根瘤菌属豆科植物天然种群中质粒传递动力学与伙伴质量的进化 | Vereau Gorbitz, D. | N/A | Plasmid transmission dynamics and evolution of partner quality in a natural population of Rhizobium leguminosarum | |
| 一种实用且安全的氮芥对角膜损伤的模型 | Sandoval-Castellanos, A. M. | N/A | A Practical and Safe Model of Nitrogen Mustard Injury in Cornea | |
| 通过使用轴向电极，提升光纤神经接口在光遗传学和电生理学中的去简并性 | Sui, K. | N/A | Lifting the degeneracy of optical fiber neural interfaces for optogenetics and electrophysiology by using axialtrodes | |
| 视网膜色素变性突变型光感受器神经元中ER聚集导致突触蛋白失衡 | Thompson, S. | N/A | ER Aggregation Causes Synaptic Protein Imbalance in Retinitis Pigmentosa Mutant Photoreceptor Neurons | |
| 在酵母中重现小鼠基因进化军备竞赛揭示了SLXL1/SLX与SLY1/2竞争结合Spindlins。 | Arlt, M. F. | N/A | Reenacting a mouse genetic evolutionary arms race in yeast reveals SLXL1/SLX compete with SLY1/2 for binding to Spindlins. | |
| 在人类世，遗传多样性的丧失将在栖息地破坏结束后仍持续很长时间。 | Mualim, K. S. | N/A | Genetic diversity loss in the Anthropocene will continue long after habitat destruction ends | |
| 一种快速、简便且经济的分离核糖体和翻译机器用于结构和功能研究的方法 | Erath, J. | N/A | A rapid, facile, and economical method for the isolation of ribosomes and translational machinery for structural and functional studies | |
| 空间转录组学分析揭示了晚期卵巢透明细胞癌的肿瘤内异质性：上皮-间质梯度的存在 | Truong Le, T. | N/A | Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient | |
| 高级卵巢透明细胞癌的空间转录组分析揭示了肿瘤内上皮-间质梯度的异质性 | Truong Le, T. | N/A | Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient | |
| 高级卵巢透明细胞癌的空间转录组学分析揭示了肿瘤内上皮-间质梯度的异质性 | Truong Le, T. | N/A | Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient | |
| 烟酰胺代谢重编程驱动胶质母细胞瘤细胞的可逆性衰老 | Narayanan, A. | N/A | Nicotinamide Metabolism Reprogramming Drives Reversible Senescence of Glioblastoma Cells | |
| 空间生物学的保守原则定义了肿瘤异质性及对免疫治疗的反应 | Behera, V. | N/A | Conserved principles of spatial biology define tumor heterogeneity and response to immunotherapy | |
| 苦味受体激动剂可诱导甲状腺乳头状癌凋亡 | Wei, K. | N/A | Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer | |
| ALDH1亚型特异性抑制剂靶向三阴性乳腺癌中的关键细胞群体 | PEREZ, M. | N/A | ALDH1 subtype-specific inhibitor targets key cell populations in triple negative breast cancer | |
| Hv1质子通道缺陷增强巨噬细胞抗原呈递及胶质瘤中的抗肿瘤反应 | Zheng, J. | N/A | Deficiency of Hv1 Proton Channel Enhances Macrophage Antigen Presentation and Anti-Tumor Responses in Glioma | |
| 人工选择与皮肤微生物群独立预测寄生虫抗性 | Kramp, R. D. | N/A | Artificial Selection and the Skin Microbiome Independently Predict Parasite Resistance | |
| 邻接算法中的混合种群：一种五分类群的几何分析 | Zhang, J. Z. | N/A | Admixed populations in the neighbor-joining algorithm: a geometric analysis with five taxa | |
| 通过位点特异性掺入基于转子的荧光非规范氨基酸，在活细胞中实时可视化蛋白质微环境变化，具有高空间分辨率 | Yang, S. | N/A | Real-Time Visualization of Protein Microenvironment Changes with High Spatial Resolution in Live Cells via Site-Specific Incorporation of Rotor-Based Fluorescent Noncanonical Amino Acids | |
| 具有可调特性的双面蛋白质纳米材料的计算设计 | Rankovic, S. | N/A | Computational design of bifaceted protein nanomaterials with tailorable properties | |
| 快速微流控灌注系统能够控制由Na+/H+交换体NHE1调节的细胞内pH动态变化。 | Tran, Q. D. | N/A | Rapid microfluidic perfusion system enables controlling dynamics of intracellular pH regulated by Na+/H+ exchanger NHE1 | |
| p-ClustVal：一种新颖的p进制方法用于增强高维单细胞RNA测序数据的聚类分析 | Sharma, P. | N/A | p-ClustVal: A Novel p-adic Approach for Enhanced Clustering of High-Dimensional scRNASeq Data | |
| 生成式人工智能在药物发现中的应用：基于GPT-2和LSTM模型的EGFR抑制剂设计 | Dasser, O. | N/A | Generative AI for Drug Discovery: A GPT-2 and LSTM Based Models for Designing EGFR Inhibitors | |
| 利用SearchNovo弥合数据库搜索与从头肽段测序之间的差距 | Xia, J. | N/A | Bridging the Gap between Database Search and De Novo Peptide Sequencing with SearchNovo | |
| LP-Micro通过利用微生物生物标志物及其随时间变化的影响，提供可解释的疾病结果预测。 | Dai, Y. | N/A | LP-Micro Offers Interpretable Disease Outcome Prediction by Leveraging Microbial Biomarkers and Their Time-Varying Effects | |
| 对人类蛋白质组功能注释的纵向分析揭示了持续的高偏差 | Phan, A. | N/A | A Longitudinal Analysis of Function Annotations of the Human Proteome Reveals Consistently High Biases | |
| 使用群论和对称元素建模心电图（ECG）波形 | Frueh, S. J. | N/A | Modeling Electrocardogram (ECG) Waveforms Using Group Theory and Symmetry Elements | |
| CryoLike：一个用于冷冻电镜图像到结构似然计算的Python包 | Tang, W. S. | N/A | CryoLike: A python package for cryo-electron microscopy image-to-structure likelihood calculations | |
| 特化细胞和转运蛋白介导慈鲷幼体皮肤吸收环境肽。 | Con, P. | N/A | Specialized cells and transporters mediate integument-absorption of environmental peptides in cichlids larvae. | |
| 火星磁场和重力场对秀丽隐杆线虫多代的影响 | Akinosho, A. | N/A | Effects of Martian magnetic and gravitational fields across multiple generations of the nematode C. elegans | |
| 冻结区动力学的数学建模：朝着在冷冻治疗中使用热成像仪的方向发展 | Ivakhnenko, O. V. | N/A | Mathematical modeling of the frozen zone dynamics: towards using thermal imagers in cryotherapy | |
| 竞争性互动塑造了跨物种的大脑动力学和计算能力 | Luppi, A. I. | N/A | Competitive interactions shape brain dynamics and computation across species | |
| 纤维微观结构分位数（FMQ）回归：一种分析从外围到核心的白质束的新型统计方法 | Lan, Z. | N/A | Fiber Microstructure Quantile (FMQ) Regression: A Novel Statistical Approach for Analyzing White Matter Bundles from Periphery to Core | |
| 纤维微观结构分位数（FMQ）回归：一种分析从外围到核心的白质束的新型统计方法 | Lan, Z. | N/A | Fiber Microstructure Quantile (FMQ) Regression: A Novel Statistical Approach for Analyzing White Matter Bundles from Periphery to Core | |
| 通过PANDORA-seq技术揭示的阿尔茨海默病小鼠模型中线粒体小RNA变化与溶酶体活性增加相关 | Zhang, X. | N/A | Mitochondrial small RNA alterations associated with increased lysosome activity in an Alzheimer's Disease Mouse Model uncovered by PANDORA-seq | |
| 学术成就与心理健康：贫困儿童前额叶-顶叶-默认模式网络耦合的悖论 | Pacheco, S. | N/A | Academic Success and Mental Health: The Paradox of Frontoparietal-Default Mode Network Coupling among Children Facing Poverty | |
| 可诱导的胰腺REG/Reg异构体，而非组成型异构体，受肠道微生物群和胰腺疾病调控。 | Zhou, Y. | N/A | Inducible, but not constitutive, pancreatic REG/Reg isoforms are regulated by intestinal microbiota and pancreatic diseases | |
| 人类腺样体的单细胞转录组分析揭示了气道微褶细胞的分子特征 | Alvarez-Arguedas, S. | N/A | Single cell transcriptional analysis of human adenoids identifies molecular features of airway microfold cells | |
| 在基因流动较高的局部适应种群中，遗传分化主要受限于染色体倒位和假定的着丝粒。 | Akopyan, M. | N/A | Genetic differentiation is constrained to chromosomal inversions and putative centromeres in locally adapted populations with higher gene flow | |
| 利用病原体防御权衡管理作物害虫对生物防治产生抗性的风险。 | Mangan, R. M. | N/A | Exploiting pathogen defence trade-offs to manage risks of crop pests evolving resistance to biocontrol. | |
| 对贝加尔湖海豹及其他海豹科动物进行全基因组重测序，以一窥其遗传多样性、种群历史及系统发育关系。 | Nebenfuehr, M. | N/A | Whole-genome re-sequencing of the Baikal seal and other phocid seals for a glimpse into their genetic diversity, demographic history, and phylogeny | |
| 在单核苷酸分辨率下，人群之间人类肠道微生物组的基因组多样性和基础代谢变异 | Dong, Q. | N/A | Genomic diversity and underlying metabolic variations of the human gut microbiome between populations at single nucleotide resolution | |
| 加拿大卡尔加里市弓河中微塑料的九个分离株的完整基因组序列 | Goff, K. L. | N/A | Complete genome sequences of nine isolates from microplastics in the Bow River, Calgary, Canada | |
| 开发用于人C肽分泌的片上荧光各向异性免疫分析法揭示了示踪剂优化的通用路线图 | Wang, Y. | N/A | Development of an on-chip fluorescence anisotropy immunoassay for human C-peptide secretion reveals a general roadmap for tracer optimization | |
| 多通道漏斗适应传感管（MFAST）用于寄生虫的简单和双检测 | Peng, R. | N/A | Multi-Channel Funnel Adapted Sensing Tube (MFAST) for the Simple and Duplex Detection of Parasites | |
| 基于注意力机制的深度神经网络模型，用于从多组学数据中在单细胞水平检测顺式调控元件 | Murakami, K. | N/A | An attention-based deep neural network model to detect cis-regulatory elements at the single-cell level from multi-omics data | |
| ABCB4的膜依赖性动态变化及双重转运机制：分子动力学模拟的见解 | Crespi, V. | N/A | Membrane-Dependent Dynamics and Dual Translocation Mechanisms of ABCB4: Insights from Molecular Dynamics Simulations | |
| 等离子体膜的纳米级曲率通过核变形和破裂调节机械适应性。 | Francis, E. A. | N/A | Nanoscale curvature of the plasma membrane regulates mechanoadaptation through nuclear deformation and rupture | |
| 关联无序激活域集合与基因表达水平 | Flores, E. | N/A | Correlating Disordered Activation Domain Ensembles with Gene Expression Levels | |
| 无标度群体行为和上皮活性固体中的巨幅波动 | Shen, Y. | N/A | Scale-free flocking and giant fluctuations in epithelial active solids | |
| 电刺激期间猴子V1区局部场电位的层特异性动力学 | Lee, S. | N/A | Layer-specific dynamics of local field potentials in monkey V1 during electrical stimulation | |
| 通过AFM纳米动态力学分析鉴定出的胶原超微结构粘弹性行为 | Asgari, M. | N/A | Ultrastructural viscoelastic behavior of collagen identified by AFM nano-dynamic mechanical analysis | |
| 基于功能性单细胞方法理解恩杂鲁胺耐药性的发展 | Xue, C. | N/A | Understanding the development of enzalutamide resistance based on a functional single-cell approach | |
| 氯胺酮代谢物（2R,6R）-羟基去甲氯胺酮诱导的海马突触快速增强持久地预处理突触可塑性 | Brown, K. A. | N/A | RAPID HIPPOCAMPAL SYNAPTIC POTENTIATION INDUCED BY KETAMINE METABOLITE (2R,6R)-HYDROXYNORKETAMINE PERSISTENTLY PRIMES SYNAPTIC PLASTICITY | |
| 转录组分析揭示了牛结核病易感性的品种特异性免疫特征 | Kumar, R. | N/A | Transcriptomic profiling identifies breed-specific immune signatures of Tuberculosis susceptibility in cattle | |
| 在啮齿动物中，背侧海马和腹侧海马分别靶向内侧前额叶皮层的不同细胞群体 | Aleman-Andrade, P. | N/A | Dorsal-caudal and ventral hippocampus target different cell populations in the medial frontal cortex in rodents | |
| 针对乙酰基转移酶NAT10进行靶向治疗，可以纠正人类额颞叶神经元的病理变化，并在果蝇体内tau蛋白病变的模型中延长寿命。 | Paonessa, F. | N/A | Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal neurons and extends lifespan in an in vivo Drosophila tauopathy model | |
| 视交叉上核的连接组组织 | Liu, J. | N/A | Connectomic Organization of the Suprachiasmatic Nucleus | |
| 探索在HIV-1感染的体内模型中，胞外囊泡、树突状细胞免疫受体与microRNA-155之间的关系，以理解疾病并开发新疗法 | Boucher, J. | N/A | Exploring the Relationship Between Extracellular Vesicles, the Dendritic Cell Immunoreceptor and microRNA-155 in an In Vivo Model of HIV-1 Infection to Understand the Disease and Develop New Treatments | |
| Cdc42的缺失导致小鼠视杯形态发生异常及小眼症 | Hofstetter, K. S. | N/A | Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse | |
| 古老而依然存活的杨树克隆体“潘多”中的体细胞突变镶嵌图 | Pineau, R. | N/A | Mosaic of Somatic Mutations in the Ancient and Still-Living Aspen Clone, Pando | |
| 十倍扩展的基质辅助激光解吸电离质谱成像技术，以500纳米分辨率对组织和细胞进行成像 | Xie, C. | N/A | Ten-Fold Expansion MALDI Mass Spectrometry Imaging of Tissues and Cells at 500 nm Resolution | |
| PSKH1激酶活性通过别构结合Ca2+传感器蛋白而受到差异性调节 | Horne, C. | N/A | PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins | |
| THRESHOLD：一种综合性的转录组分析工具，用于评估基因饱和度及其在疾病进展中的影响 | Gammell, F. M. | N/A | THRESHOLD: A Comprehensive Transcriptomic Analysis Tool for Evaluating Gene Saturation and Impact in Disease Progression | |
| 利用原代人神经干细胞和祖细胞模拟胶质瘤的瘤内异质性 | Gao, D. | N/A | Modeling Glioma Intratumoral Heterogeneity with Primary Human Neural Stem and Progenitor Cells | |
| KRAS G12突变等位基因通过FOXO1调控谷氨酰胺代谢的差异性 | Ber, S. | N/A | KRAS G12 mutant alleles differentially control glutamine metabolism via FOXO1 | |
| 前额叶抑制在被动应对行为中的关键作用：慢性压力与速效抗抑郁药 | Fong, T. H. | N/A | Key contribution of prefrontal inhibition to passive coping behaviour: chronic stress and fast-acting antidepressant | |
| 嗅觉中的数据科学 | agarwal, v. K. | N/A | Data Science in Olfaction | |
| scAGCI：一种基于锚点图的细胞聚类方法，用于从整合的单细胞RNA测序（scRNA-seq）和单细胞ATAC测序（scATAC-seq）数据中进行细胞聚类。 | Dong, Y. | N/A | scAGCI: an anchor graph-based method for cell clustering from integrated scRNA-seq and scATAC-seq data | |
| 控制生物分子凝聚物中界面蛋白质的吸附、解吸和聚集 | Visser, B. | N/A | Controlling interfacial protein adsorption, desorption and aggregation in biomolecular condensates | |
| Capicua在德国小蠊卵巢中维持前后轴 | Elshaer, N. | N/A | Capicua maintains anterior-posterior axis in Blattella germanica ovaries | |
| 温度依赖性和性别特异性的表型可塑性在Heliconius charithonia中 | Seixas, F. A. | N/A | Temperature-dependent and sex-specific phenotypic plasticity in Heliconius charithonia | |
| 在分化中的晶状体纤维细胞中，核仁核糖体RNA的持续合成一直持续到突然的核降解，这是实现眼睛晶状体透明性所必需的。 | Rayee, D. | N/A | Continuous nucleolar ribosomal RNA synthesis in differentiating lens fiber cells until abrupt nuclear degradation required for ocular lens transparency | |
| 整合的局部和系统性交流因素调控发育性造血过程中新生造血祖细胞的逃逸 | Shalaby, C. | N/A | Integrated local and systemic communication factors regulate nascent hematopoietic progenitor escape during developmental hematopoiesis | |
| 环境线索影响河狸筑坝活动中建筑活动的时机和地点 | Kennedy, J. R. | N/A | Environmental cues influence timing and location ofconstruction activity in a beaver damming complex | |
| 生态和社会因素导致埋葬甲虫中两性间的亲代抚育行为存在差异。 | Ma, D. | N/A | Ecological and social factors lead to variation in parental care between sexes in a burying beetle | |
| 在序列学习任务中，人类是资源理性的预测者 | Ferdinand, V. | N/A | Humans are resource-rational predictors in a sequence learning task | |
| AnimalMotionViz：一种利用计算机视觉技术追踪和可视化动物运动模式的交互式软件工具 | De Castro, A. L. | N/A | AnimalMotionViz: an interactive software tool for tracking and visualizing animal motion patterns using computer vision | |
| 执行控制可以查询隐藏的人类记忆 | Zhao, C. | N/A | Executive control can query hidden human memories | |
| 人类前驱期和早期帕金森病及大鼠模型中的纵向神经黑色素变化 | Perot, J.-B. | N/A | Longitudinal neuromelanin changes in prodromal and early Parkinson's disease in humans and rat model | |
| 诱导神经元的转录特征可区分病毒学抑制的HIV感染者与非HIV感染者 | Ostermann, P. N. | N/A | A Transcriptional Signature of Induced Neurons Differentiates Virologically Suppressed People Living With HIV from People Without HIV | |
| 骨髓源性的β-己糖胺酶对神经健康和溶酶体功能至关重要：对Sandhoff病的启示 | Tsourmas, K. I. | N/A | Myeloid-derived β-hexosaminidase is essential for neuronal health and lysosome function: implications for Sandhoff disease | |
| 严重脊髓性肌萎缩症中D-和L-氨基酸失衡调节谷氨酸能神经传递。 | Hassan, A. | N/A | Dysregulated balance of D- and L-amino acids modulating glutamatergic neurotransmission in severe spinal muscular atrophy. | |
| 线性化与预测：一种基于储备计算的脑数字孪生方法 | Di Antonio, G. | N/A | Linearizing and forecasting: a reservoir computing route to digital twins of the brain | |
| 视觉工作记忆中边界或独立特征的保持是任务依赖的 | Cao, R. | N/A | Maintenance of Bound or Independent Features in Visual Working Memory is Taskdependent | |
| 间歇性干扰电流刺激对迷走神经中器官特异性纤维时空激活的控制 | Rossetti, N. | N/A | Control of spatiotemporal activation of organ-specific fibers in the vagus nerve by intermittent interferential current stimulation | |
| 捕捉生物物理神经模型中的动态涌现结构 | Milinkovic, B. | N/A | Capturing the emergent dynamical structure in biophysical neural models | |
| 捕捉生物物理神经模型中的新兴动力学结构 | Milinkovic, B. | N/A | Capturing the emergent dynamical structure in biophysical neural models | |
| 内皮细胞Nrf2调控系统性损伤后的神经炎症 | Zou, H. | N/A | Endothelial cell Nrf2 controls neuroinflammation following a systemic insult | |
| Opto2P-FCM：一种基于MEMS的微型双光子显微镜，具有双光子图案化光遗传刺激功能 | Futia, G. L. | N/A | Opto2P-FCM: A MEMS based miniature two-photon microscope with two-photon patterned optogenetic stimulation | |
| 在蝙蝠卡罗利亚（Carollia perspicillata）中，听觉阈值因性别而异，但与年龄无关。 | Molano, O. | N/A | Hearing thresholds in the bat Carollia perspicillata vary by sex but not age | |
| 语音编码在衰老和失语症中的时空动力学 | Kries, J. | N/A | The spatio-temporal dynamics of phoneme encoding in aging and aphasia | |
| 利用空间转录组学和类器官技术定义猪母胎界面细胞多样性 | McCutcheon, C. | N/A | Defining Cellular Diversity at the Swine Maternal-Fetal Interface Using Spatial Transcriptomics and Organoids | |
| 自噬在生殖系干细胞中是可有可无的，但在果蝇卵巢生态位中维持帽细胞则需要自噬。 | Nilangekar, K. S. | N/A | Autophagy is dispensable in germline stem cells but is required in the cap cells for their maintenance in the Drosophila ovarian niche | |
| 干细胞和祖细胞的增殖由细胞类型特异性的周期蛋白D基因独立调控。 | Lush, M. E. | N/A | Stem and progenitor cell proliferation are independently regulated by cell type-specific cyclinD genes | |
| 细胞增殖的局部控制是斑马鱼神经丘再生的基础 | Lavalle, N. G. | N/A | Local control of cellular proliferation underlies neuromast regeneration in zebrafish | |
| 氧气水平改变牛早期胚胎的能量代谢 | Boskovic, N. | N/A | Oxygen level alters energy metabolism in bovine preimplantation embryos | |
| 背外侧前额叶皮层神经活动的损伤在帕金森病早期即出现 | Hjelle, N. | N/A | Impairment of Neuronal Activity in the Dorsolateral Prefrontal Cortex Occurs Early in Parkinsonism | |
| 星形胶质细胞TrkB.T1缺陷破坏了谷氨酸能突触的形成以及星形胶质细胞与突触的相互作用。 | Pinkston, B. T. C. | N/A | Astrocyte TrkB.T1 deficiency disrupts glutamatergic synaptogenesis and astrocyte-synapse interactions. | |
| Shc1与Frs2和Shp2合作，在FGF诱导的晶状体发育中招募Grb2 | Wang, Q. | N/A | Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development | |
| 经皮迷走神经刺激在感知决策过程中提高了错误后的准确性 | Su, S. | N/A | Transcutaneous Vagus Nerve Stimulation Boosts Post-Error Accuracy During Perceptual Decision-Making | |
| 针对果蝇中央复合体的细胞类型特异性驱动线及其用于研究神经肽表达和睡眠调控的应用 | Wolff, T. | N/A | Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation | |
| 未甲基化全突变携带者的转录组分析表明TET3在脆性X综合征中FMR1 CGG重复扩增甲基化动力学中的作用 | Farmiloe, G. | N/A | Transcriptomic profiling of unmethylated full mutation carriers implicates TET3 in FMR1 CGG repeat expansion methylation dynamics in Fragile X syndrome | |
| 利用生长素诱导降解子2技术揭示单个突触快速蛋白质清除的急性后果 | Elbaum, L. | N/A | Revealing Acute Consequences of Rapid Protein Elimination at Individual Synapses using Auxin-Inducible Degron 2 Technology | |
| 通过自我调节体感活动增强人体感觉运动整合 | Iwama, S. | N/A | Enhanced human sensorimotor integration via self-modulation of the somatosensory activity | |
| 使用具有分化簇基因启动子的病毒载体，以靶向大脑中的特定细胞类型 | Uesaka, N. | N/A | Viral vectors with cluster of differentiation gene promoters to target specific cell types in the brain | |
| 阿尔茨海默病5XFAD小鼠的空间记忆通过XPO1抑制剂KPT-330得到增强 | Wong, S. Q. | N/A | Spatial memory in Alzheimer's disease 5XFAD mice is enhanced by XPO1 inhibitor KPT-330 | |
| 视觉对象优化头部方向编码 | Siegenthaler, D. | N/A | Visual objects refine head direction coding | |
| 代理体感图谱平铺视觉皮层 | Hedger, N. | N/A | Vicarious Somatotopic Maps Tile Visual Cortex | |
| 实验室间微球免疫测定法的协调：用于干燥血斑和口腔液体中SARS-CoV-2抗体检测 | DeRosa, K. L. | N/A | Inter-laboratory harmonization of microsphere immunoassays for SARS-CoV-2 antibody detection in dried blood spots and oral fluids | |
| 工程化蛋白质去稳定化逆转了内在免疫逃避，以实现候选疫苗泛株KSHV和SARS-CoV-2抗原 | Wan, L. | N/A | Engineered protein destabilization reverses intrinsic immune evasion for candidate vaccine pan-strain KSHV and SARS-CoV-2 antigens | |
| 真菌性脑膜炎病原体的表型景观揭示了其独特的生物学特性 | Boucher, M. | N/A | Phenotypic landscape of a fungal meningitis pathogen reveals its unique biology | |
| 单细胞转录组学揭示了皮肤细胞特异性的抗真菌免疫反应，以及新兴真菌病原体白色念珠菌的IL-1Ra- IL-1R免疫逃避策略 | Balakumar, A. | N/A | Single-Cell Transcriptomics Unveils Skin Cell Specific Antifungal Immune Responses and IL-1Ra- IL-1R Immune Evasion Strategies of Emerging Fungal Pathogen Candida auris | |
| MIIST305 能够减轻胃肠道急性放射综合征损伤，并改善放射引起的肠道菌群失调。 | Mitra, D. | N/A | MIIST305 mitigates gastrointestinal acute radiation syndrome injury and ameliorates radiation-induced gut microbiome dysbiosis | |
| 一种针对微生物组衍生疗法的靶向发现和表征的理性方法 | Krause, L. | N/A | A rational approach for the targeted discovery and characterisation of microbiome-derived therapeutics | |
| HPAIV H5N1在生牛奶、废水和表面上的环境稳定性 | Kaiser, F. | N/A | Environmental stability of HPAIV H5N1 in raw milk, wastewater and on surfaces | |
| 进化距离较远的细菌之间抗生素抗性基因的转移 | Parras-Molto, M. | N/A | The transfer of antibiotic resistance genes between evolutionary distant bacteria | |
| 被遗忘的迷幻剂：2C-B和psilocybin给药后脑组织的空间时间映射 | Mallaroni, P. | N/A | The forgotten psychedelic: Spatiotemporal mapping of brain organisation following the administration of 2C-B and psilocybin | |
| 功能性超声成像揭示了临床脊髓刺激的激活特性 | Lim, K. | N/A | Functional Ultrasound Imaging Reveals Activation Properties of Clinical Spinal Cord Stimulation | |
| 人类在嘈杂环境中对语音感知的神经功能和因果机制 | Ceravolo, L. | N/A | Functional and causal neural mechanisms of human voice perception in noisy situations | |
| 基于连接组学的预测模型：一般和特定认知控制的预测模型 | Qu, S. | N/A | Connectome-based Predictive Models of General and Specific Cognitive Control | |
| 人类短连合纤维比长纤维更细，且髓鞘化程度较低。 | Ruthig, P. | N/A | Human short association fibers are thinner and less myelinated than long fibers | |
| 一种主动电感应的端到端模型 | Turcu, D. | N/A | An end-to-end model of active electrosensation | |
| 帕金森病在运动准备期间扰乱了前辅助运动区的神经调节 | Hendrix, C. M. | N/A | Parkinsonism disrupts neuronal modulation in the pre-supplementary motor area during movement preparation | |
| Arc通过细胞外囊泡介导细胞间tau传递 | Tyagi, M. | N/A | Arc mediates intercellular tau transmission via extracellular vesicles | |
| Bcl11b通过细胞自主、非细胞自主和亚细胞机制调控小脑下投射神经元的轴突发育 | Itoh, Y. | N/A | Bcl11b orchestrates subcerebral projection neuron axon development via cell-autonomous, non-cell-autonomous, and subcellular mechanisms | |
| 听觉带状皮层中对侧编码的分层涌现 | Johnson, J. S. | N/A | Hierarchical emergence of opponent coding in auditory belt cortex | |
| 大麻二酚逆转了精神分裂症小鼠模型中的小胶质细胞激活、小清蛋白中间神经元和神经元周围网的损失。 | Rodrigues da Silva, N. | N/A | Cannabidiol reverses microglia activation and loss of parvalbumin interneurons and perineuronal nets in a mouse model of schizophrenia | |
| 催产素神经元在社交和非社交环境中，通过状态依赖的信号传递，调控产热和行为觉醒的转变。 | Vandendoren, M. | N/A | Oxytocin neurons signal state-dependent transitions to thermogenesis and behavioral arousal in social and non-social settings. | |
| 关系是资源还是负担？依恋风格、关系质量和伴侣间应对与浪漫伴侣在场时急性心理社会压力的关联 | Gallistl, M. | N/A | Relationship as resource or burden? Associations of attachment style, relationship quality and dyadic coping with acute psychosocial stress in the presence of the romantic partner | |
| α-突触核蛋白病理进展的网络分析揭示p21激活激酶作为脆弱性的调节因子 | Vatsa, N. | N/A | Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability | |
| 一种具有增强信噪比性能的128通道接收阵列，用于10.5特斯拉脑部成像 | Lagore, R. L. | N/A | A 128-channel receive array with enhanced SNR performance for 10.5 tesla brain imaging | |
| 40 Hz光刺激恢复了阿尔茨海默病模型小鼠早期脑动力学改变及联想记忆 | Aguilera, M. | N/A | 40 Hz light stimulation restores early brain dynamics alterations and associative memory in Alzheimer's disease model mice | |
| 共享和个体体验的神经相关性 | Coppola, P. | N/A | The neural correlates of shared and individual experience | |
| 伏隔核中的5-HT2C受体限制了MDMA的奖赏效应。 | Pomrenze, M. B. | N/A | 5-HT2C receptors in the nucleus accumbens constrain the rewarding effects of MDMA | |
| 适当选择参考电极并进行重新参考，以减轻单脉冲电刺激数据中的偏差 | Huang, H. | N/A | Proper reference selection and re-referencing to mitigate bias in single pulse electrical stimulation data | |
| 干扰素介导的自然杀伤细胞激活与SARS-CoV-2感染期间有限的病毒中和广度相关 | de los Rios Kobara, I. | N/A | Interferon-mediated NK cell activation is associated with limited neutralization breadth during SARS-CoV-2 infection | |
| Wag31，一种膜系绳，对分枝杆菌中的脂质稳态至关重要。 | Kapoor, Y. | N/A | Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria | |
| 鱼类作为河流抗菌素耐药性监测的哨兵效果不佳 | Tskhay, F. | N/A | Fish are poor sentinels for surveillance of riverine AMR | |
| 多酚重塑微生物群落可减少甲烷排放 | McGivern, B. B. | N/A | Polyphenol rewiring of the microbiome reduces methane emissions | |
| 空间的重要性：受移动限制的虚拟行人会影响个人的避让行为 | Nikmanesh, M. | N/A | Space matters: virtual pedestrians with mobility constraints affect individuals' avoidance behaviours | |
| 酮症通过改善生物能量代谢提升抗氧化能力并增强神经功能：一项1H磁共振波谱研究 | van Nieuwenhuizen, H. | N/A | Ketosis Elevates Antioxidants and Enhances Neural Function Through Improved Bioenergetics: A 1H MR Spectroscopy Study | |
| 活体双光子荧光显微镜中的自适应光学校正与神经场 | Kang, I. | N/A | Adaptive optical correction in in vivo two-photon fluorescence microscopy with neural fields | |
| 局部姿势变化会在关节、躯干和面部周围引发广泛而多样的皮肤伸展。 | Rupani, M. | N/A | Local postural changes elicit extensive and diverse skin stretch around joints, on the trunk, and the face | |
| 基于生物性别（男性与女性）对受试者进行分组的局限性及新方法：从伏隔核核心内多巴胺诱导的精神兴奋剂活性中获得的启示。 | Job, M. O. | N/A | Limitations of grouping subjects based on biological sex (males versus females) and a new approach: insights from intra-nucleus accumbens core dopamine-induced psychostimulant activity. | |
| 针对小麦叶际细菌的新型噬菌体携带DNA修饰和单链断裂 | Dougherty, P. E. | N/A | Novel bacteriophages targeting wheat phyllosphere bacteria carry DNA modifications and single-strand breaks | |
| 通过恢复衰老的成骨前体细胞来促进骨修复 | Reeves, J. | N/A | Rejuvenating aged osteoprogenitors for bone repair | |
| Zyxin的缺失减少了内皮炎症并减轻了动脉粥样硬化 | Huang, H. | N/A | Deletion of Zyxin Reduces Endothelial Inflammation and Mitigates Atherosclerosis | |
| 在侵袭和相关吞噬过程中，会形成一个独特的PI(4,5)P2区室。 | Durgan, J. | N/A | A distinctive PI(4,5)P2 compartment forms during entosis and related engulfment processes | |
| 由于上皮-间质转化导致的化疗耐药性是由异常的脂质代谢平衡引起的。 | Matsumoto, A. | N/A | Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance | |
| NIPBL和STAG1通过提供差异化的DNA-凝聚素亲和力来实现环挤压。 | van Wee, R. | N/A | NIPBL and STAG1 enable loop extrusion by providing differential DNA-cohesin affinity | |
| # BioRxiv 2024-10-21 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 大学考试与心理社会压力：对学生皮质醇节律性的影响 | Borghi, F. | N/A | University Exams and Psychosocial Stress: Effects on Cortisol Rhythmicity in Students | |
| 通过木质素复合物持续清除活性氧并改善细胞周围氧合作用，挽救HIF-1α和VEGF水平，从而促进糖尿病伤口的新血管生成和愈合。 | Jung, J. P. | N/A | Sustained ROS Scavenging and Pericellular Oxygenation by Lignin Composites Rescue HIF-1α and VEGF Levels to Improve Diabetic Wound Neovascularization and Healing | |
| 血清素调节非快速眼动睡眠期间齿状回的次慢振荡 | Turi, G. F. | N/A | Serotonin modulates infraslow oscillation in the dentate gyrus during Non-REM sleep | |
| 机器学习预测酶的最适pH值 | Gado, J. E. | N/A | Machine learning prediction of enzyme optimum pH | |
| 基于YAP驱动的口腔上皮干细胞恶性重编程的单细胞分辨率研究 | Faraji, F. | N/A | YAP-Driven Oral Epithelial Stem Cell Malignant Reprogramming at Single Cell Resolution | |
| 预测亲和力通过同源性（PATH）：利用持久同源性进行可解释的结合亲和力预测 | Long, Y. | N/A | Predicting Affinity Through Homology (PATH): Interpretable Binding Affinity Prediction with Persistent Homology | |
| 自然杀伤细胞的细胞毒性塑造了B细胞白血病的克隆进化 | Buri, M. C. | N/A | Natural killer cell cytotoxicity shapes the clonal evolution of B cell leukaemia | |
| 神经纤毛蛋白-1是NGF和TrkA引发疼痛的共受体。 | Peach, C. J. | N/A | Neuropilin-1 is a co-receptor for NGF and TrkA-evoked pain | |
| 一类新型的人类CpG岛启动子，具有灵长类特异性重复序列 | Mohan, K. N. | N/A | A new class of human CpG island promoters with primate-specific repeats | |
| 正交化的人类蛋白酶调控分泌信号 | Aldrete, C. A. | N/A | Orthogonalized human protease control of secreted signals | |
| 无性生殖的旋口虫Adineta vaga中的跨代染色体修复 | Houtain, A. | N/A | Transgenerational chromosome repair in the asexual bdelloid rotifer Adineta vaga | |
| 疟原虫电子传递链中细胞色素c和c1的生物发生 | Garcia-Guerrero, A. E. | N/A | Biogenesis of cytochromes c and c1 in the electron transport chain of malaria parasites | |
| 致癌性STIL介导的BRCA1功能丧失导致DNA损伤和中心体扩增 | Sanghi, S. | N/A | Oncogenic STIL-mediated loss of BRCA1 functionality causes DNA damage and centrosome amplification | |
| 童年虐待相关的腹内侧前额叶皮层周围神经网增加中微胶质细胞参与的证据 | Belliveau, C. | N/A | Evidence of microglial involvement in the childhood abuse-associated increase in perineuronal nets in the ventromedial prefrontal cortex | |
| 通过综合转录组和表观基因组分析揭示癌症驱动基因——Moonlight | Nourbakhsh, M. | N/A | Revealing cancer driver genes through integrative transcriptomic and epigenomic analyses with Moonlight | |
| 投射至腹侧CA1区的内梨状神经元是识别记忆的关键节点。 | Yamawaki, N. | N/A | Endopiriform neurons projecting to ventral CA1 are a critical node for recognition memory | |
| 三部分ATP非依赖性周质（TRAP）转运蛋白结合Neu5Ac的分子决定因素 | Goyal, P. | N/A | Molecular determinants of Neu5Ac binding to tripartite ATP independent periplasmic (TRAP) transporter | |
| 墨西哥洞穴鱼在短睡眠状态下表现出升高的DNA损伤，但无衰老迹象 | Lloyd, E. | N/A | Elevated DNA Damage without signs of aging in the short-sleeping Mexican Cavefish | |
| SCREP：通过药理基因组嵌入增强的元预训练和少样本迁移学习实现单细胞药物反应预测 | Ge, S. | N/A | SCREP: Towards Single-Cell Drug Response Prediction by Pharmacogenomic Embedding Enhanced Meta-Pretraining and Few-Shot Transfer Learning | |
| T细胞上PIK3IP1/TrIP的下调受TCR信号强度、PKC以及金属蛋白酶介导的切割调控。 | Murter, B. M. | N/A | Downregulation of PIK3IP1/TrIP on T cells is controlled by TCR signal strength, PKC, and metalloprotease-mediated cleavage | |
| 酵母剪接因子Fyv6对3'剪接位点选择的调控 | Senn, K. | N/A | Control of 3' splice site selection by the yeast splicing factor Fyv6 | |
| 在阿尔茨海默病的小鼠模型中，记忆编码和巩固所依赖的海马功能障碍先于明显的β淀粉样蛋白沉积发生。 | Li, H. | N/A | Impaired hippocampal functions underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of Alzheimer's disease | |
| 前生物气体流动环境能够实现等温核酸复制 | Schwintek, P. | N/A | Prebiotic gas flow environment enables isothermal nucleic acid replication | |
| 样式偏转由叶序的左右手性和具有镜像花朵的物种中生长素诱导的细胞伸长差异决定。 | Robertson, C. | N/A | Style deflection is determined by the handedness of phyllotaxis and auxin-induced differential cell elongation in a species with mirror-image flowers | |
| 嗅觉组合编码支持秀丽隐杆线虫的风险-回报决策 | Saad, M. Z. H. | N/A | Olfactory combinatorial coding supports risk-reward decision making in C. elegans | |
| 陆地植物的核基因组和细胞器基因组的进化速率是相互关联的。 | Asar, Y. | N/A | Evolutionary rates of nuclear and organellar genomes are linked in land plants | |
| 使用生成对抗网络（GANs）对长基因序列进行潜在生成建模 | Szatkownik, A. | N/A | Latent generative modeling of long genetic sequences with GANs | |
| 熵产生限制了基因调控中的信息传递 | Gehri, M. | N/A | Entropy production constrains information throughput in gene regulation | |
| BioLP-bench：评估大型语言模型对生物实验室协议的理解能力 | Ivanov, I. | N/A | BioLP-bench: Measuring understanding of biological lab protocols by large language models | |
| 在学习过程中，丘脑核团与皮层网络之间的功能连接发生了渐进性变化。 | Jarrett, C. E. | N/A | Progressive changes in functional connectivity between thalamic nuclei and cortical networks across learning | |
| 用于预测转录组结构的长上下文RNA基础模型 | Saberi, A. | N/A | A long context RNA foundation model for predicting transcriptome architecture | |
| 大脑活动能够区分同一环境的声学模拟 | Matten, V. G. | N/A | Brain activity discriminates acoustic simulations of the same environment | |
| 大脑活动能够区分同一环境的声学模拟 | Matten, V. G. | N/A | Brain activity discriminates acoustic simulations of the same environment | |
| 转录依赖的移植染色体在人工细胞中的膨胀 | Greiss, F. | N/A | Transcription-dependent swelling of a transplanted chromosome in an artificial cell | |
| 解开睫状层的秘密：睫状糖萼的高分辨率结构与功能 | Hoepfner, L. M. | N/A | Unwrapping the ciliary coat: high-resolution structure and function of the ciliary glycocalyx | |
| 使用合成轴突形态生成全脑连接组 | Petkantchin, R. | N/A | Generating brain-wide connectome using synthetic axonal morphologies | |
| PROPERMAB：一种综合框架，利用机器学习进行抗体可开发性的计算机预测 | Li, B. | N/A | PROPERMAB: an integrative framework for in silico prediction of antibody developability using machine learning | |
| 冷冻电子断层扫描揭示了黄病毒的复制、出芽和成熟过程的耦合关系。 | Dahmane, S. | N/A | Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation | |
| 褐藻门三角褐指藻Seipin同源基因的功能研究揭示了硅藻脂滴生物发生过程的独特特征。 | Le Moigne, D. | N/A | Functional study of Phaeodactylum tricornutum Seipin homolog highlights unique features of lipid droplets biogenesis in diatoms. | |
| 单羧酸转运蛋白转运甲状腺素分子机制 | Tassinari, M. | N/A | Molecular mechanism of thyroxine transport by monocarboxylate transporters | |
| 开发并验证了一种开源的“手性判断任务”，适用于面对面和在线研究 | Moreno-Verdu, M. | N/A | Development and validation of an open-source Hand Laterality Judgement Task for in-person and online studies | |
| 通过解决GPT不准确的回答并进行情境基准测试来创建生物医学知识库 | Darnell, S. S. | N/A | Creating a biomedical knowledge base by addressing GPT inaccurate responses and benchmarking context | |
| 在异种Caenorhabditis胚胎中，杂交不亲和性在一细胞阶段显现。 | Bloom, J. | N/A | Hybrid incompatibility emerges at the one-cell stage in interspecies Caenorhabditis embryos | |
| ISG15在癌症生物学中的作用：在泛癌背景下系统评估ISG15表达及其分子相互作用 | Chatterjee, S. | N/A | The Role of ISG15 in Cancer Biology: Systematic Evaluation of ISG15 Expression and Its Molecular Interactions in a Pan-Cancer Context | |
| ZNFX1是一种新型主调控因子，参与癌症中表观遗传诱导的病原体模拟和炎症小体信号传导 | Stojanovic, L. | N/A | ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer | |
| 生物科学博士在出版方面存在明显的性别和种族/族裔差异模式。 | Azurdia, D. E. | N/A | Distinct patterns of bioscience doctoral publication disparities by gender and race/ethnicity | |
| 使用增强型SCas12a检测方法实现高结构RNA的无扩增精确检测 | Zhang, J. | N/A | Precise amplification-free detection of highly structured RNA with an enhanced SCas12a assay | |
| 利用GPT-4自动整理泛素-蛋白酶体系统中的E3-底物关系 | Zhang, Z. | N/A | Harnessing GPT-4 for Automated Curation of E3-Substrate Relationships in the Ubiquitin-Proteasome System | |
| 体内功能分析与人类Glp1r A316T变异体的结构特征 | El Eid, L. | N/A | In vivo functional profiling and structural characterisation of the human Glp1r A316T variant | |
| 通过空间蛋白质组学揭示初级纤毛的内在多样性 | Lundberg, E. | N/A | Intrinsic Diversity in Primary Cilia Revealed Through Spatial Proteomics | |
| 依赖于Ca2+的囊泡和非囊泡脂质转移控制低渗质膜扩张 | Mu, B. | N/A | Ca2+-dependent vesicular and non-vesicular lipid transfer controls hypoosmotic plasma membrane expansion | |
| 复制依赖性组蛋白（Repli-Histo）标记在活体人类细胞中解析常染色质/异染色质的物理特性。 | Minami, K. | N/A | Replication-dependent histone (Repli-Histo) labeling dissects the physical properties of euchromatin/heterochromatin in living human cells. | |
| 使用webKnossos在电子显微镜体积中高效地进行全细胞线粒体映射 | Jiang, Y. | N/A | Efficient cell-wide mapping of mitochondria in electron microscopic volumes using webKnossos | |
| 在秀丽隐杆线虫卵母细胞中，减数分裂I和II之间的染色体被一个细胞质分裂囊泡所包围。 | El Mossadeq, L. | N/A | An interkinetic envelope surrounds chromosomes between meiosis I and II in C. elegans oocytes | |
| Sec14L6是一种促进脂滴形成的PS和PI4P转运蛋白。 | zhou, t. | N/A | Sec14L6 is a PS and PI4P transporter that promotes lipid droplet formation | |
| 哺乳动物细胞核内厚横纹线状纤维的检测与电子显微镜研究 | Mosevitsky, M. I. | N/A | Detection and electron microscopic study of thick cross-striated linear fibrils in mammalian cell nuclei | |
| 在果蝇雄性和雌性的连续同源附肢发育过程中重新连接的基因相互作用 | Ridgway, A. M. | N/A | Rewired gene interactions during development of serially homologous appendages in male and female Drosophila | |
| miR-210基因座缺失破坏细胞稳态；一项综合遗传学研究 | Preda, M. B. | N/A | miR-210 locus deletion disrupts cellular homeostasis; an integrated genetic study | |
| 从哔哔声到街道：揭示听觉情境中的感官输入与相关性 | Korte, S. | N/A | From Beeps to Streets: Unveiling Sensory Input and Relevance Across Auditory Contexts | |
| 光学模糊对ON和OFF视觉通路的影响不同 | Pons, C. | N/A | Optical blur affects differently ON and OFF visual pathways | |
| 岛屿杂交蝴蝶谱系的起源 | Boman, J. | N/A | On the origin of an insular hybrid butterfly lineage | |
| 植物相关泛菌中质粒驯化的演化：大规模获得遗传冗余后伴随差异性基因丢失 | Picazo, D. R. | N/A | Evolution of plasmid domestication in plant-associated Pantoea: massive gain of genetic redundancy followed by differential gene loss | |
| 大麻二酚（CBD）增强了雌性和雄性小鼠下丘脑-垂体-肾上腺（HPA）轴反应性的生理和行为标志。 | Jenkins, B. W. | N/A | Cannabidiol (CBD) potentiates physiological and behavioral markers of hypothalamic-pituitary-adrenal (HPA) axis responsivity in female and male mice | |
| 使用HPM Live μ的Live-HPF CLEM：在每个干草堆中找回所有针。CLEM的最后前沿。 | Heiligenstein, X. | N/A | Live-HPF CLEM using the HPM Live μ: Finding back all needles in every haystack. The last frontier in CLEM | |
| TFAP2C和HNRNPK调控mTOR细胞代谢及朊病毒传播 | Sellitto, S. | N/A | TFAP2C and HNRNPK control mTOR cell metabolism and prion propagation | |
| 顶端网格蛋白包被的胞吞凹陷控制上皮微绒毛的生长和大小 | Perkins, O. L. | N/A | Apical clathrin-coated endocytic pits control the growth and size of epithelial microvilli | |
| 在T细胞群中出现了协同运动，但在中性粒细胞群中则没有出现。 | Wortel, I. M. N. | N/A | Cooperative motility emerges in crowds of T cells but not neutrophils | |
| 主题 使用反向相关法改进听觉表征的特征描述指南 | Gezae, G. W. | N/A | Subject Instructions for Improved Characterization of Auditory Representations Using Reverse Correlation | |
| lucie: 一个改进的用于从UCI机器学习库加载数据集的Python包 | Ge, K. | N/A | lucie: An Improved Python Package for Loading Datasets from the UCI Machine Learning Repository | |
| 在使用readmers和hapmers评估牛津纳米孔测序读取错误纠正后的相位切换时 | Elbers, J. P. | N/A | Using readmers and hapmers in assessing phase switching after read error correction of Oxford Nanopore Sequences | |
| 解密基本原子相互作用以统一生成分子对接与设计 | Peng, X. | N/A | Decipher Fundamental Atomic Interactions to Unify Generative Molecular Docking and Design | |
| 癌症相关脂肪细胞通过FGF21驱动的脂肪分解介导CD8+T细胞功能障碍 | Dalangood, S. | N/A | Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis | |
| 烟草烟雾暴露是头颈部癌症中氧化应激反应和免疫功能改变的驱动因素。 | Sandulache, V. C. | N/A | Tobacco smoke exposure is a driver of altered oxidative stress response and immunity in head and neck cancer | |
| 转录组分析揭示了一群先前未知的Cdkn2a阳性肿瘤相关巨噬细胞，存在于侵袭性脑癌中。 | Melo dos Santos, L. S. | N/A | Transcriptional profiling reveals a previously unknown population of Cdkn2a-positive tumor-associated macrophages in aggressive brain cancer | |
| 经皮递送的超可变形阳离子脂质体复合物miR211-5p（UCL-211）稳定了BRAFV600E+黑色素细胞痣 | Chhibber, T. | N/A | Transdermal Delivery of Ultradeformable Cationic Liposomes Complexed with miR211-5p (UCL-211) Stabilizes BRAFV600E+ Melanocytic Nevi | |
| 热带气候下叶菜类蔬菜的氮离子组动态 | Shenhar, I. | N/A | Nitrogen ionome dynamics on leafy vegetables in tropical climate | |
| 解决光暗转换时非光化学淬灭的非常规信号 | Lam, L. | N/A | Resolving an unconventional non-photochemical quenching signature at the light-to-dark transition | |
| 构建脓毒症模型：数据整合揭示了严重铜绿假单胞菌感染的致病机制。 | Messina, F. | N/A | Building a model of sepsis: data integration unravels pathogenic mechanisms in severe P. aeruginosa infections. | |
| 朝向生物分子凝聚体中集体相互作用的通用模型 | Fuxreiter, M. | N/A | Towards universal models for collective interactions in biomolecular condensates | |
| 多时间尺度神经适应支撑长期肌肉骨骼重塑。 | philipp, R. | N/A | Multi-timescale neural adaptation underlying long-term musculoskeletal reorganization. | |
| 新型FKBP12配体MP-004的局部给药可改善视网膜色素变性模型中的视网膜功能和结构。 | Lara-Lopez, A. | N/A | Topical administration of novel FKBP12 ligand MP-004 improves retinal function and structure in retinitis pigmentosa models. | |
| 六种腺相关病毒载体血清型在小鼠下丘脑和大脑中的比较分析 | Witteveen, I. | N/A | Comparative analysis of six adeno-associated viral vector serotypes in mouse inferior colliculus and cerebellum | |
| 泡沫状小胶质细胞与多发性硬化症进展中的氧化脂质相关 | van der Vliet, D. | N/A | Foamy microglia link oxylipins to disease progression in multiple sclerosis | |
| μ和δ阿片受体通过不同的细胞和分子机制调节前额叶皮层内的抑制作用 | Cole, R. H. | N/A | Mu and Delta Opioid Receptors Modulate Inhibition within the Prefrontal Cortex through Dissociable Cellular and Molecular Mechanisms | |
| 灰葡萄孢菌（Botrytis cinerea）中缺乏植原毒素生产能力的突变体的毒力丧失，可以通过修改接种培养基来恢复。 | Qin, S. | N/A | Loss of virulence of Botrytis cinerea mutants defective in phytotoxin production is restored by modifying inoculation medium | |
| 通过刺激血流介导的血管融合，实现Galen静脉畸形血管的逆转 | Martin-Valiente, E. | N/A | Reversal of vein of Galen aneurysmal malformation by stimulation of flow-mediated vessel fusion | |
| 模拟欧洲人畜共患脑炎（TBE）风险在时空上的年度变化 | Dagostin, F. | N/A | Modeling the spatio-temporal annual changes in human tick-borne encephalitis (TBE) risk in Europe | |
| 模拟气候变暖情景导致独居蜂的羽化时间提前和体重减轻增加，但对越冬存活率没有影响。 | Möllmann, J. S. | N/A | Simulated climate warming scenarios lead to earlier emergence and increased weight loss but have no effect on overwintering survival in solitary bees | |
| 树冠的自修剪受功能策略和邻域相互作用的影响。 | Kothari, S. | N/A | Self-pruning in tree crowns is influenced by functional strategies and neighborhood interactions | |
| 磷的可用性作为温带生物多样性草本植被中营养限制的主要决定因素 | Van Sundert, K. | N/A | Phosphorus availability as the primary determinant of nutrient limitation in temperate biodiverse herbaceous vegetation | |
| 进化宏观生态学：在基于过程、前瞻时间的模拟模型中更明确地纳入系统发育信息 | Culshaw, V. | N/A | Evolutionary macroecology: Incorporating phylogenetic information more explicitly into process-based, forward time, simulation models | |
| 广食性微生物捕食者——盘基网柄菌（Dictyostelium discoideum）的猎物吸引力 | Shreenidhi, P. M. | N/A | Prey attraction in a generalist microbial predator, Dictyostelium discoideum | |
| 在多维连续空间中建立本地适应的等位基因 | Sakamoto, T. | N/A | Establishment of a locally adaptive allele in multidimensional continuous space | |
| rs2069845多态性与全关节置换术期间IL-6和可溶性IL-6受体水平相关。 | Anderson, K. D. | N/A | Polymorphisms in rs2069845 are associated with IL-6 and soluble IL-6 receptor levels during total joint replacement | |
| 450K和EPIC v2.0阵列之间的时间性和生物性衰老的兼容性和比较分析 | De Pourcq, S. | N/A | Compatibility and comparative analysis of chronological and biological aging between the legacy 450K and the EPIC v2.0 arrays | |
| 对从腹泻患者中分离出的多重耐药粘质沙雷菌株IU-BTGE-M-3的比较基因组研究揭示了抗生素耐药性特征 | Hossain, M. S. | N/A | Comparative Genome Study of Multidrug-resistant Serratia marcescens strain IU-BTGE-M-3 Isolated from a Diarrheal Patient Reveals Antibiotic Resistance Profile | |
| 表达驱动的遗传依赖性揭示了精准医疗的目标 | Elmas, A. | N/A | Expression-Driven Genetic Dependency Reveals Targets for Precision Medicine | |
| 前额叶皮层缺陷是创伤后应激障碍的一个假定易感因素 | Nalloor, R. I. | N/A | Prefrontal Cortical Deficits are a Putative Susceptibility Factor for PTSD | |
| ProtNote：一种用于蛋白质功能注释的多模态方法 | Char, S. | N/A | ProtNote: a multimodal method for protein-function annotation | |
| 跑步时缩短飞行时间会减少胫腓骨应变：有限元分析 | Khassetarash, A. | N/A | Reducing flight time during running decreases tibial-fibular strains: a finite element analysis | |
| 受物理启发的模型对接配体复合物精度估计器 | Bae, B. | N/A | Physics-inspired accuracy estimator for model-docked ligand complexes | |
| 使用惯性矩张量分析对肺癌候选基因进行优先排序 | Dwivedi, A. | N/A | Prioritization of Lung Cancer Candidate Genes using Moment of Inertia Tensor Analysis | |
| 组合连锁不平衡与连锁分析（cLDLA）：在生物信息学工作流程中实现一种强大的方法，用于识别复杂性状的遗传基础。 | Upadhyay, M. | N/A | Combined Linkage Disequilibrium and Linkage Analysis (cLDLA): implementation of a powerful approach to identify the genetic basis of complex traits in a bioinformatics workflow. | |
| 表面活性剂和成膜聚合物对体外测量的肺表面活性剂功能的影响是剂量率依赖性的。 | Sengupta, S. | N/A | The effect of surfactants and film-forming polymers on pulmonary surfactant function measured in vitro is dose-rate dependent | |
| 删除率限制乳腺癌和卵巢癌的启动 | Houlahan, K. | N/A | Deletions Rate-Limit Breast and Ovarian Cancer Initiation | |
| IDH突变型胶质瘤起源于携带初始驱动突变的胶质祖细胞。 | Park, J. W. | N/A | IDH-mutant gliomas arise from glial progenitor cells harboring the initial driver mutation | |
| S100a4阳性肺泡巨噬细胞通过促进脂肪酸代谢加速癌前病变不典型腺瘤样增生的进展 | Huang, H. | N/A | S100a4+ alveolar macrophages accelerate the progression of precancerous atypical adenomatous hyperplasia by promoting fatty acid metabolism | |
| 整合素α1β1在小鼠多囊肾病模型中促进间质纤维化 | Grenier, C. | N/A | Integrin alpha1 beta1 promotes interstitial fibrosis in a mouse model of polycystic kidney disease | |
| 性激素和季节变化对褪黑素抑制及光警觉反应的影响 | Fazlali, F. | N/A | Sex and seasonal variations in melatonin suppression, and alerting response to light | |
| 在固定期间进行的次最大离心训练并不能防止老年或年轻大鼠的串联肌节丢失或机械功能障碍。 | Hinks, A. A. | N/A | Submaximal eccentric training during immobilization does not prevent serial sarcomere loss or impairments in mechanical function in old or young rats | |
| 二维猪结肠类器官模型的开发与特性研究：用于肠道生理学与屏障功能的研究 | Plenge, M. | N/A | Development and Characterization of a 2D Porcine Colonic Organoid Model for Studying Intestinal Physiology and Barrier Function | |
| 病毒感染和温度对不同温度耐受性甜瓜和西葫芦植株基因响应的综合影响 | de Moya-Ruiz, C. | N/A | The combined effect of viral infection and temperature on the gene response of melon and zucchini plants with different levels of temperature tolerance | |
| 蛋白质分解产物作为基于血液的衰老生理标志物：来自狗衰老项目的发现 | Harrison, B. R. | N/A | Protein catabolites as blood-based biomarkers of aging physiology: Findings from the Dog Aging Project | |
| 在癌症的网络基础分层分析中整合基因和基因表达数据 | Liou, K. | N/A | Integrating genetic and gene expression data in network-based stratification analysis of cancers | |
| 系统性CGRP和PACAP-38对C57BL/6J小鼠运动诱发恶心和平衡行为的影响：一项比较研究 | Rahman, S. M. | N/A | Systemic CGRP and PACAP-38's Effects on Motion-Induced Nausea and Balance Behaviors in C57BL/6J Mice: A Comparison | |
| 使用电影刺激模拟人类社会视觉 | Santavirta, S. | N/A | Modelling human social vision with cinematic stimuli | |
| 神经元TDP-43聚集在肌萎缩侧索硬化症中驱动小胶质细胞形态变化，先于免疫表型出现。 | Swanson, M. E. V. | N/A | Neuronal TDP-43 aggregation drives changes in microglial morphology prior to immunophenotype in amyotrophic lateral sclerosis | |
| 不公平会引发愤怒还是厌恶？基于25年神经影像学的定量神经功能剖析 | Gan, X. | N/A | Does Unfairness Evoke Anger or Disgust? A Quantitative Neurofunctional Dissection Based on 25 Years of Neuroimaging | |
| hnRNP A2/B1剪接变体的细胞质积累在FUS相关的小鼠ALS模型中促成了毒性作用。 | Rossi, S. | N/A | Cytoplasmic accumulation of a splice variant of hnRNP A2/B1 contributes to FUS-associated toxicity in a mouse model of ALS | |
| 非致幻的5-羟色胺1B受体对于裸盖菇素在小鼠中的抗抑郁样效应是必要的。 | Fleury, S. | N/A | The non-hallucinogenic serotonin 1B receptor is necessary for the antidepressant-like effects of psilocybin in mice | |
| 人类空间导航过程中前额叶Theta和顶叶Alpha振荡事件的单次试验特征 | Cuello, M. T. | N/A | Single trial characterization of frontal Theta and parietal Alpha oscillatory episodes during Spatial Navigation in humans | |
| 一种测量骑行期间动机相关事件相关电位（ERP）指标的方法 | Renoud-Grappin, R. | N/A | A Measure of Event-Related Potentials (ERP) Indices of Motivation During Cycling | |
| 一项大规模的非注意盲视实验揭示了身体检测的反转效应 | Gandolfo, M. | N/A | A body detection inversion effect revealed by a large-scale inattentional blindness experiment | |
| 在斑马鱼幼体中M电流对初级运动神经元兴奋性控制的发展变化 | Gaudreau, S. F. | N/A | Developmental changes in the control of primary motoneuron excitability by the M-current in larval zebrafish | |
| 从卵到内脏：新种Sodalis nezarae sp. nov.与南方绿蝽Nezara viridula的共生关系 | Rogowska-van der Molen, M. A. | N/A | From Eggs to Guts: Symbiotic Association of Sodalis nezarae sp. nov. with the Southern Green Shield Bug Nezara viridula | |
| 基础EFNA3通过促进氧化磷酸化（OXPHOS），促进乳腺上皮细胞的管腔驱动迁移和癌症转移 | Chen, J. | N/A | Basal EFNA3 Facilitates Luminal-Driving Mammary Epithelial Migration and Cancer Metastasis by Promoting OXPHOS | |
| 寨卡病毒和登革病毒通过不同地调控宿主mRNA加工因子来定义其毒力 | Scholl, A. | N/A | Zika and Dengue Viruses Differentially Modulate Host mRNA Processing Factors Defining Its Virulence | |
| 基于模型的紫罗兰植物细胞分批培养表现出抗疟和抗癌活性 | R, B. | N/A | Model-based fed-batch cultivation of Viola odorata plant cells exhibiting antimalarial and anticancer activity | |
| 体内保护效果：大黄素在达尔顿腹水淋巴瘤诱导的瑞士白化小鼠中的保护作用 | Suluvoy, J. K. | N/A | In vivo Protective Efficacy of Emodin in Swiss Albino Mice Induced with Dalton Ascitic Lymphoma | |
| 系统性和局部慢性炎症以及激素分布促进了老年女性乳腺癌易感环境的发展。 | Carleton, N. | N/A | Systemic and local chronic inflammation and hormone disposition promote a tumor-permissive environment for breast cancer in older women | |
| 基于形态学和分子证据，华东地区一种新的荚蒾属（忍冬科）植物——荚蒾属新种 | Zhao, L. | N/A | A new synonym for Viburnum erosum (Viburnaceae) in East China, based on morphological and molecular evidence | |
| 孟加拉国退化栖息地中濒危的西白眉长臂猿（Hoolock hoolock）的蠕虫寄生虫感染情况 | Kabir, M. T. | N/A | Helminthic parasite infections of endangered western hoolock gibbons (Hoolock hoolock) in degraded habitats of Bangladesh | |
| 雄性特异性sNPF肽能神经回路通过神经-胶质相互作用控制能量平衡以调节交配时长。 | Zhang, X. | N/A | Male-specific sNPF peptidergic circuits control energy balance for mating duration through neuron-glia interactions. | |
| 在功能性PET（fPET）-FDG的分析中：基线特征的错误描述可能导致代谢（去）激活的伪影。 | Coursey, S. E. | N/A | On the analysis of functional PET (fPET)-FDG: baseline mischaracterization can introduce artifactual metabolic (de)activations | |
| 纹状体中持续性和相位性多巴胺释放的宽带比率测量 | Gottschalk, A. | N/A | Wideband ratiometric measurement of tonic and phasic dopamine release in the striatum | |
| 吗啡诱导的痛觉过敏影响小细胞外囊泡miRNA组成和功能 | Reddy, D. | N/A | Morphine-induced hyperalgesia impacts small extracellular vesicle miRNA composition and function | |
| 在生态学和进化领域，朝着更全面验证基于机器学习的研究方法迈进 | Christensen, C. | N/A | Moving towards more holistic validation of machine learning-based approaches in ecology and evolution | |
| 研究3'UTR中CpG岛DNA甲基化在癌症中的作用 | Wilson, C. | N/A | Investigating the role of CpG island DNA methylation at 3'UTRs in cancer | |
| 骨盆环骨折：脊柱骨盆对位是否影响骶骨和腰骨盆固定稳定性？ | Tripathi, S. | N/A | Pelvic Ring Fractures: Does Spinopelvic Alignment Affect Sacral and Lumbopelvic Fixation Stability? | |
| DeepVul：一种用于联合预测基因必需性和药物反应的多任务Transformer模型 | Jararweh, A. | N/A | DeepVul: A Multi-Task Transformer Model for Joint Prediction of Gene Essentiality and Drug Response | |
| 分子动力学模拟揭示了非天然相互作用在调节孕酮受体从非活性到活性构象转变中的重要性 | Hazarika, S. | N/A | Molecular Dynamics Simulations Reveal the Importance of Non-Native Interactions in Modulating the Inactive to Active Conformational Transition in Progesterone Receptor | |
| ACSS2在乳腺癌脑转移细胞中通过E2F1依赖的方式调控铁死亡 | Esquea, E. | N/A | ACSS2 regulates ferroptosis in an E2F1-dependent manner in breast cancer brain metastatic cells | |
| 受体信号放大定量分析：完全激动剂的Kd/EC50比值作为增益参数 | Buchwald, P. | N/A | Quantification of Signal Amplification for Receptors: The Kd/EC50 Ratio of Full Agonists as a Gain Parameter | |
| E3泛素连接酶LIFERING以酰基辅酶A脱氢酶样蛋白IBR3为目标，进行泛素化，并在DNA损伤时协调细胞增殖和细胞死亡。 | Kallai, B. | N/A | LIFERING, an E3 ligase, targets the acyl-CoA dehydrogenase-like protein IBR3, for ubiquitination and coordinates cell proliferation and cell death upon DNA damage | |
| 蛋白酶体抑制通过下调HLA-E增强潜伏逆转并提升NK细胞介导的HIV-1感染细胞清除 | Laeremans, T. | N/A | Proteasome inhibition enhances latency reversal and boosts NK cell-mediated elimination of HIV-1 infected cells through HLA-E downregulation | |
| 脂肪酸去饱和酶通过连接细胞代谢途径来促进EB病毒感染的B细胞的增殖。 | Bonglack, E. N. | N/A | Fatty acid desaturases link cell metabolism pathways to promote proliferation of Epstein-Barr virus-infected B cells | |
| 军团菌科家族的扩展、重构与特征描述 | Gabrielli, M. | N/A | Expansion, restructuring and characterization of the Legionellaceae family | |
| 晶体学和核磁共振研究显示，肺炎链球菌LCP蛋白PsrSp中四个长环的动力学对配体特异性具有重要意义。 | Sandalova, T. | N/A | Crystallographic and NMR studies of Streptococcus pneumonia LCP protein PsrSp indicate the importance of dynamics in four long loops for ligand specificity | |
| 揭示肠道微生物组网络指纹：一种用于预测黑色素瘤患者免疫治疗反应的深度学习方法。 | Sun, J. | N/A | Unveiling the Gut Microbiome Network Fingerprint: A Deep Learning Approach to Predict Immunotherapy Response in Melanoma Patients. | |
| 拟杆菌属和福氏杆菌属原噬菌体多样性、宿主范围及时间稳定性的见解 | Hedzet, S. | N/A | Insights into Diversity, Host-Range, and Temporal Stability of Bacteroides and Phocaeicola Prophages | |
| 一种巴斯德氏菌表面的脂蛋白能够结合补体因子I，以促进免疫逃避。 | Nguyen, Q. H. | N/A | A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion. | |
| 可遗传的种子携带细菌的优先效应推动了小麦根际微生物群的早期构建 | Garrido-Sanz, D. | N/A | Priority effects of heritable seed-borne bacteria drive early assembly of the wheat rhizosphere microbiome | |
| O特异性抗原的丧失塑造了铜绿假单胞菌在小鼠临床前肺部感染模型中的微生物地理分布 | Fraser, H. | N/A | Loss of O-specific antigen shapes Pseudomonas aeruginosa microbiogeography in murine preclinical pulmonary infection model | |
| 一种基因组显著缩小的红假单胞菌菌株保留了其属的核心代谢多功能性。 | Oda, Y. | N/A | A Rhodopseudomonas strain with a substantially smaller genome retains the core metabolic versatility of its genus | |
| 禽源硝基呋喃妥因耐药大肠杆菌的动物源性传播潜力 | Sealey, J. | N/A | The Zoonotic Potential of Poultry-Associated Nitrofurantoin-Resistant Escherichia coli | |
| 苯并异噁唑-4,7-二酮类化合物的药物化学研究揭示了核糖体小亚基作为特定分枝杆菌翻译准确性靶点的潜力。 | Wu, J. | N/A | Medicinal chemistry of benzoisoxazole-4,7-dione analogues identifies the ribosomal small subunit as a target for specific mycobacterial translational fidelity | |
| 通过流式细胞术对水生生态系统进行高通量病毒计数 | Bellanger, M. | N/A | High Throughput Viral Enumeration of Aquatic Ecosystems via Flow Cytometry | |
| 铜绿假单胞菌通过代谢交叉喂养支持坏疽性拟杆菌在囊性纤维化肺部多菌种群落中的生存。 | El Hafi, B. | N/A | Pseudomonas aeruginosa supports the survival of Prevotella melaninogenica in a cystic fibrosis lung polymicrobial community through metabolic cross-feeding | |
| P3 定点突变：基于带有3'突出端的引物对的高效方法 | Mousavi, N. | N/A | P3 site-directed mutagenesis: An efficient method based on primer pairs with 3-prime overhangs | |
| 通过不育昆虫技术（SIT）在佛罗里达州卡皮塔岛对埃及伊蚊的抑制，2020年至2022年 | Morreale, R. | N/A | SUPPRESSION OF AEDES AEGYPTI BY STERILE INSECT TECHNIQUE (SIT) ON CAPTIVA ISLAND, FLORIDA, USA FROM 2020 TO 2022 | |
| 自然杀伤细胞和单核细胞的综合转录组分析：推进COVID-19的诊断和治疗策略 | Loukman, S. | N/A | Integrative Transcriptomic Profiling of NK Cells and Monocytes: Advancing Diagnostic and Therapeutic Strategies for COVID-19. | |
| 这是SPRTA：在疫情规模下评估系统发育置信度 | De Maio, N. | N/A | This is SPRTA: assessing phylogenetic confidence at pandemic scales | |
| 工程设计抗逆基因驱动以实现可持续的疟疾控制：预测、测试及克服目标位点抗性 | Morianou, I. | N/A | Engineering Resilient Gene Drives Towards Sustainable Malaria Control: Predicting, Testing and Overcoming Target Site Resistance | |
| 除核糖体外，整个蛋白质翻译机器的自发生物发生 | Schwarz-Schilling, M. | N/A | Autonomous biogenesis of the entire protein translation machinery excluding ribosomes | |
| 精确连续尖峰率推断 | Stern, M. | N/A | Exact Continuous Spiking Rate Inference | |
| 神经和行为的重现共同反映了叙事事件的提取。 | Nau, M. | N/A | Neural and behavioral reinstatement jointly reflect retrieval of narrative events | |
| DprA招募ComM，以促进革兰氏阴性菌在自然转化过程中进行重组 | Dalia, T. N. | N/A | DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria | |
| 开发和利用表达绿色荧光蛋白的梅毒螺旋体以研究螺旋体与宿主的相互作用及抗体介导的清除机制：扩展梅毒研究工具箱。 | Delgado, K. N. | N/A | Development and utilization of Treponema pallidum expressing green fluorescent protein to study spirochete-host interactions and antibody-mediated clearance: expanding the toolbox for syphilis research. | |
| 新鉴定的SpoVAF/FigP复合物：在中等高压下枯草芽孢杆菌孢子萌发中的作用及影响因素 | Lyu, F. | N/A | Newly identified SpoVAF/FigP complex: the role in Bacillus subtilis spore germination at moderate high pressure and influencing factors | |
| A群链球菌的甘露糖磷酸转移酶系统（Man-PTS）影响抗菌活性及特定鼻咽感染的生态位。 | Marple, A. C. | N/A | The Streptococcus pyogenes mannose phosphotransferase system (Man-PTS) influences antimicrobial activity and niche-specific nasopharyngeal infection | |
| 一种用于体外发现和体内测试恶性疟原虫疟疾传播阻断药物的一体化流程 | Brancucci, N. M. B. | N/A | An all-in-one pipeline for the in vitro discovery and in vivo testing of Plasmodium falciparum malaria transmission blocking drugs | |
| 基于单细胞转录组学和多重抗体成像的人类精子发生时空图谱 | Hikmet, F. | N/A | A spatiotemporal atlas of human spermatogenesis based on single-cell transcriptomics and multiplex antibody imaging | |
| 禾谷镰刀菌铜胺氧化酶通过将植物防御化合物水解产生的色胺转化为生长素，从而冗余地增加致病性。 | Svoboda, T. | N/A | Fusarium graminearum copper amine-oxidases redundantly increase virulence by converting tryptamine from hydrolyzed plant defense compounds into auxin | |
| 走向一个统一的尾噬菌体系统发育框架 | Weinheimer, A. R. | N/A | Towards a unifying phylogenomic framework for tailed phages | |
| 使用AlphaFold深入探究Polo样激酶活性的结构调控 | Wyatt, M. D. | N/A | Insights into the Structural Regulation of Polo-Like Kinase Activity using AlphaFold | |
| 工程化的Bxb1变体提高了整合酶活性和保真度 | Rose, J. | N/A | Engineered Bxb1 variants improve integrase activity and fidelity | |
| TALE蛋白的计算重设计用于DNA模板化的蛋白质纤维组装 | de Haas, R. J. | N/A | Computational redesign of TALE proteins for DNA-templated assembly of protein fibers | |
| 合成生物学中的多功能系统：利用单链DNA信号实现基因激活的精准控制 | Ng, B. | N/A | Multifunctional Systems in Synthetic Biology: Single-Stranded DNA Signaling for Precise Control of Gene Activation | |
| 基于显著性的刺激选择在鸟类中脑峡部大细胞部中的叠加抑制性环绕机制 | Qian, L. | N/A | Superimposed inhibitory surrounds underlying Saliency-based Stimulus Selection in avian Midbrain isthmi pars magnocellularis | |
| 通过Type V CRISPR-Cas12a系统设计的人类线粒体DNA定向缺失 | Nikitchina, N. | N/A | Targeted deletions in human mitochondrial DNA engineered by Type V CRISPR-Cas12a system | |
| 扩展采样方法用于巨冠蝾螈（Triturus cristatus）的环境DNA监测 | Harper, L. R. | N/A | Extending sampling approaches for great crested newt (Triturus cristatus) eDNA monitoring | |
| 可持续农业实践的生态和经济效益：来自大面积谷物作物农场试验的证据 | Mata, L. | N/A | The ecological and economic benefits of sustainable agricultural practices: Evidence from on-farm trials in broad-acre grain crops | |
| 极地浮游宿主中藻类质体和线粒体的劫持与整合 | Rao, A. K. | N/A | Hijacking and Integration of Algal Plastids andMitochondria in a Polar Planktonic Host | |
| 在加拿大萨斯卡通市，从城市到乡村的梯度上，草原驼鹿的空间和时间分布情况 | Harris, K. E. | N/A | Spatial and temporal occurrences of prairie moose across an urban to rural gradient in Saskatoon, Canada | |
| 载脂蛋白A-IV多态性Q360H和T347S的结构分析阐明了其抗血栓形成的作用机制 | Shoara, A. A. | N/A | Structural analyses of apolipoprotein A-IV polymorphisms Q360H and T347S elucidate the inhibitory effect against thrombosis | |
| 通过神经递质转运蛋白4（NTT4，SLC6A17）转运谷氨酰胺在中枢神经系统兴奋性突触处维持突触前谷氨酸供应 | Nicoli, A. L. | N/A | Glutamine Transport via Neurotransmitter Transporter 4 (NTT4, SLC6A17) Maintains Presynaptic Glutamate Supply at Excitatory Synapses in the Central Nervous System | |
| 解聚F-肌动蛋白可加速多能性退出，从而增强干细胞衍生的胰岛分化 | Hogrebe, N. J. | N/A | Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation | |
| 集群组装动力学驱动平面细胞极性极化的保真度 | Nissen, S. B. | N/A | Cluster Assembly Dynamics Drive Fidelity of Planar Cell Polarity Polarization | |
| # BioRxiv 2024-10-20 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 肺炎球菌生物合成基因突变体保留上皮微侵袭并诱导先天免疫 | Weight, C. M. | N/A | Pneumococcal biosynthesis gene mutants retain epithelial microinvasion and induce innate immunity | |
| 宏观进化最优突变率的证据 | Irlam, G. | N/A | Evidence for the macroevolutionarily optimal mutation rate | |
| 能否利用模型从动作信号中推断出关于僵硬感知的信息？ | Kossowsky Lev, H. | N/A | Can Information About Stiffness Perception be Inferred from Action Signals Using Models? | |
| 季节性迁徙的鸣禽与其留鸟亲属相比，具有不同的历史种群规模特征。 | Winker, K. | N/A | Seasonally migratory songbirds have different historic population size characteristics than resident relatives. | |
| 蛋白质-DNA簇解释了转录因子非指数DNA停留时间分布 | Kosar, Z. | N/A | Protein-DNA Clusters Explain the Non-ExponentialDNA Residence Time Distributions of TranscriptionFactors | |
| 非靶向蛋白质组学鉴定出细菌来源的ADP-核糖基转移酶AvrRpm1的植物底物 | Kaur, S. | N/A | Untargeted proteomics identifies plant substrates of the bacterial-derived ADP-ribosyltransferase AvrRpm1 | |
| 聚类内分析揭示了组织特异性的突变模式 | Choudalakis, S. | N/A | Intra-clustering analysis reveals tissue-specific mutational patterns | |
| 记忆元认知成分由楔前叶与海马间高伽马活动结构性地支持 | Pan, K. | N/A | Components of Mnemonic Metacognition Constitutionally Supported by High Gamma Activity Between the Precuneus and Hippocampus | |
| 利用nMOST技术对多种溶酶体贮积病突变体进行全球细胞蛋白质脂质组学分析 | Kraus, F. | N/A | Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST | |
| 对豆类壳二孢菌进行群体水平的基因组测序，鉴定出与菌株毒力相关的基因组位点 | Vaghefi, N. | N/A | Population-level whole genome sequencing of Ascochyta rabiei identifies genomic loci associated with isolate aggressiveness | |
| 大脑皮层对说话者频谱变化的追踪预测了选择性听觉 | Cervantes Constantino, F. | N/A | Cortical tracking of speakers' spectral changes predicts selective listening | |
| 使用诱捕法评估串联质谱分析中假发现率的控制 | Wen, B. | N/A | Assessment of false discovery rate control in tandem mass spectrometry analysis using entrapment | |
| 加速度传感与PIDA控制的生化实现 | Alexis, E. | N/A | Biochemical implementation of acceleration sensing and PIDA control | |
| 生化实现加速度传感与PIDA控制（扩展版） | Alexis, E. | N/A | Biochemical implementation of acceleration sensing and PIDA control (Extended Version) | |
| 突触蛋白的凝聚受到序列编码的分子语法调控。 | Hoffmann, C. | N/A | Synapsin condensation is governed by sequence-encoded molecular grammars | |
| 音乐性增强选择性注意：从同时神经反应的精确分离中获得的时空洞察 | Manting, C. L. | N/A | Musicality enhances selective attention: spatiotemporal insights from precise separation of simultaneous neural responses | |
| GCK-MODY中独特的持续时间和饮食依赖性脂质谱及肾脏并发症 | Huang, Y. | N/A | Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY | |
| 在破伤风毒素癫痫模型中减少突触异质性：来自计算建模的见解 | Zarei Eskikand, P. | N/A | Reduced Synaptic Heterogeneity in a Tetanus ToxinModel of Epilepsy: Insights from ComputationalModeling | |
| 具有tau病理特征的特发性震颤与阿尔茨海默病和原发性年龄相关性tau病变的种子在构象上无法区分。 | Saez-Calveras, N. | N/A | Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy | |
| 破伤风毒素癫痫大鼠模型中的动态多日癫痫发作周期：演变的节律及其对预测的影响 | Zarei Eskikand, P. | N/A | Dynamic Multiday Seizure Cycles in a Tetanus Toxin Rat Model of Epilepsy: Evolving Rhythms and Implications for Prediction | |
| BBATProt：一种通过可解释深度学习增强特征提取的生物功能预测框架 | Wang, Y. | N/A | BBATProt: A Framework Predicting Biological Function with Enhanced Feature Extraction via Explainable Deep Learning | |
| 一种分布于植物共生细菌中的排出泵家族，能够调节宿主特异性硫代葡萄糖苷在宿主和器官特异性解毒过程中的作用。 | Russ, D. | N/A | An efflux pump family distributed across plant commensal bacteria conditions host- and organ-specific detoxification of a host-specific glucosinolate | |
| 分布于植物共生细菌中的一个排出泵家族，能够调节宿主特异性硫代葡萄糖苷在宿主和器官特异性解毒作用。 | Russ, D. | N/A | An efflux pump family distributed across plant commensal bacteria conditions host- and organ-specific detoxification of a host-specific glucosinolate | |
| CRISPR相关酶在由iPSC衍生的神经元中错误定位到细胞质，导致KRAB特异性降解。 | Cajka, G. | N/A | CRISPR associated enzymes are mislocalized to the cytoplasm in iPSC-derived neurons resulting in KRAB-specific degradation | |
| 额顶叶θ同步化在因果关系上将工作记忆与冲动决策联系起来。 | Kapetaniou, G. E. | N/A | Frontoparietal theta synchronization causally links working memory with impulsive decision making | |
| 在脆性X综合征大鼠模型中，海马位置细胞序列受损。 | Donahue, M. M. | N/A | Hippocampal place cell sequences are impaired in a rat model of Fragile X Syndrome | |
| 青少年小鼠的慢性昼夜节律紊乱会损害海马体记忆，干扰基因表达的振荡。 | Gallego-Landin, I. | N/A | Chronic circadian disruption in adolescent mice impairs hippocampal memory disrupting gene expression oscillations | |
| 新发现的水生甲基杆菌A1菌株降解聚酯聚氨酯的特性研究 | Lee, S. | N/A | Characterization of Newly Discovered Polyester Polyurethane-degrading Methylobacterium Aquaticum Strain A1 | |
| 体外艰难梭菌野生菌株生物膜：根据菌株多样性的形态和特性 | LEMAIRE, A. | N/A | In vitro biofilms of Clostridioides difficile undomesticated strains: Morphology and properties according to strain diversity | |
| 针对铜绿假单胞菌III型分泌系统的保护性人源单克隆抗体可抑制转位子功能。 | Desveaux, J.-M. | N/A | Protective human monoclonal antibodies that target the Type III Secretion System of Pseudomonas aeruginosa inhibit translocon function | |
| N-MYC转录激活域与TFIIIC5 DNA结合表面相互作用的机制 | Leen, E. | N/A | Mechanism of Interaction Between the Transactivation Domain of N-MYC and the DNA-Binding Surface of TFIIIC5 | |
| 形态特异性选择压力驱动一种颜色多态鸟类表型分化 | Passarotto, A. | N/A | Morph-specific selection pressures drive phenotypic divergence in a color polymorphic bird | |
| 揭示混合模型中最大似然估计的范围。 | Heinzel, C. S. | N/A | Revealing the range of maximum likelihood estimates in the admixture model. | |
| 冷冻电镜揭示了一种单域抗体，其具有独特的结合表位，位于成纤维细胞激活蛋白α上。 | Xu, Z. | N/A | Cryo-electron microscopy reveals a single domain antibody with a unique binding epitope on fibroblast activation protein alpha | |
| 建立和表征一种用于培养肉的非贴壁昆虫细胞系 | Letcher, S. M. | N/A | Establishment & Characterization of a Non-Adherent Insect Cell Line for Cultivated Meat | |
| 使用PyProteinInference进行联合蛋白质推断分析，有助于阐明串联质谱数据背后的生物学理解。 | Hinkle, T. B. | N/A | Joint Protein Inference Analysis with PyProteinInference Elucidates Biological Understanding of Tandem Mass Spectrometry Data | |
| 苯甲脒介导的人溶菌酶聚集抑制：同源蛋白质中的差异配体结合 | Vijayan, D. K. | N/A | Benzamidine-Mediated Inhibition of Human Lysozyme Aggregation: Differential Ligand Binding in Homologous Proteins | |
| 甘蔗黄叶病毒损害了甘蔗对新蚜虫媒介Melanaphis sorghi的转录组防御反应 | Pimenta, R. J. G. | N/A | Sugarcane yellow leaf virus impairs the transcriptomic defense responses of sugarcane to its new aphid vector Melanaphis sorghi | |
| 模板驱动的动态功能网络连接预测药物治疗反应用于重度抑郁症和双相情感障碍 | Baker, B. | N/A | Template-driven dynamic functional network connectivity predicts medication response for major depression and bipolar disorders | |
| 小胶质细胞通过IGF1调节胎儿人脑中的GABA能神经发生 | Yu, D. | N/A | Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1 | |
| 半自动化监测纵向微生物代谢动力学：木质素降解研究案例 | Guimaraes Ferreira, J. V. | N/A | Semi-automated monitoring of longitudinal microbial metabolic dynamics: A study case for lignin degradation | |
| 富集精原干细胞并确定袋鼬科有袋类动物——肥尾细尾獴的睾丸周期阶段 | Tarulli, G. A. | N/A | Enrichment of spermatogonial stem cells and staging of the testis cycle in a dasyurid marsupial, the fat-tailed dunnart | |
| 骨骼肌代谢分析揭示了在秀丽隐杆线虫中延长寿命和健康寿命的正向调节因子 | Jonk, S. | N/A | Metabolic analysis of sarcopenic muscle identifies positive modulators of longevity and health span in C. elegans | |
| 利用数据高效且可解释的钾离子和氯离子传导光敏感蛋白模型对CA1神经元光遗传抑制的计算分析 | Weyn, L. | N/A | Computational analysis of optogenetic inhibition of CA1 neurons using a data-efficient and interpretable potassium and chloride conducting opsin model | |
| 生物医学大数据操作系统（Bio-OS）：一个集成化的数据密集型科学研究数据挖掘环境 | Liu, J. | N/A | Bio-medical Big Data Operating System (Bio-OS): An Integrated Data Mining Environment for Data Intensive Scientific Research | |
| 拟鲤鱼大胆-害羞行为的测量与分类 | Pierotti, S. | N/A | Measurement and classification of bold-shy behaviours in medaka fish | |
| 利用生成式人工智能在计算机中生成合成癌症基因组 | Diaz-Navarro, A. | N/A | In silico generation of synthetic cancer genomes using generative AI | |
| 全球蛋白质磷酸化反应的比较结构分析 | Correa Marrero, M. | N/A | Global comparative structural analysis of responses to protein phosphorylation | |
| ENACT：Visium高清（HD）数据的端到端分析 | Kamel, M. | N/A | ENACT: End-to-End Analysis of Visium High Definition (HD) Data | |
| 评估Pythium oligandrum和Serratia proteamaculans在控制欧洲山毛榉（Fagus sylvatica）中Phytophthora plurivora的生物防治潜力 | Kelbessa, B. G. | N/A | Evaluating the Biocontrol Potential of Pythium oligandrum and Serratia proteamaculans in Controlling Phytophthora plurivora in European beech (Fagus sylvatica) | |
| 新加坡九种常见树种光合作用温度依赖性的变异 | Teo, L. M. R. | N/A | Variations in the temperature dependence of photosynthesis among nine common tree species planted in Singapore | |
| 基于网络的研究：阿尔茨海默病中Aβ和{tau}蛋白的动力学 | Bianchi, S. | N/A | A network based study of the dynamics of Aβ and {tau} proteins in Alzheimer's disease | |
| 衰老大脑中蛋白酶体组成的改变，遗传性蛋白酶体增强减轻了与年龄相关的认知衰退，以及急性蛋白酶体激动剂治疗挽救了小鼠的年龄相关认知缺陷。 | Pickering, A. | N/A | Altered Proteasome Composition in Aging Brains, Genetic Proteasome Augmentation Mitigates Age-Related Cognitive Declines, and Acute Proteasome Agonist Treatment Rescues Age-Related Cognitive Deficits in Mice | |
| 雄激素受体对Alston鸣鼠发声回路的调节 | Zheng, D.-J. | N/A | Androgen receptor modulation of vocal circuitry in Alston's singing mouse | |
| 达尔文的本土化难题：环境压力和干扰梯度解释 | Galman, A. | N/A | Darwin's Naturalization Conundrum explained by gradients of environmental stress and disturbance | |
| 将目标捕获与全基因组测序相结合，对近期和自然历史收藏的样本进行分析，以解释野生和栽培大麻的系统地理学 | Balant, M. | N/A | Integrating target capture with whole genome sequencing of recent and natural history collections to explain the phylogeography of wild-growing and cultivated Cannabis | |
| sv-channels：使用一维卷积神经网络过滤基因组缺失 | Santuari, L. | N/A | sv-channels: filtering genomic deletions using one-dimensional convolutional neural networks | |
| 脂肪组织中的PFKFB3蛋白有助于维持全身血糖稳态。 | OLSON, A. L. | N/A | PFKFB3 protein in adipose tissue contributes to whole body glucose homeostasis | |
| inTRACKtive - 一个基于网络的工具，用于交互式细胞追踪可视化 | Huijben, T. A. P. M. | N/A | inTRACKtive - A Web-Based Tool for Interactive Cell Tracking Visualization | |
| deadtrees.earth - 一个开放访问且互动的数据库，用于厘米级航拍影像，揭示全球树木死亡动态 | Mosig, C. | N/A | deadtrees.earth - An Open-Access and Interactive Database for Centimeter-Scale Aerial Imagery to Uncover Global Tree Mortality Dynamics | |
| deadtrees.earth - 一个开放访问和互动的数据库，用于厘米级航拍影像，揭示全球树木死亡动态 | Mosig, C. | N/A | deadtrees.earth - An Open-Access and Interactive Database for Centimeter-Scale Aerial Imagery to Uncover Global Tree Mortality Dynamics | |
| 水稻田扁莎Cyperus iria的染色体水平参考基因组和微小RNA | Tsang, S. K. | N/A | Chromosomal-level reference genome and microRNAs of the ricefield flatsedge Cyperus iria | |
| 用于区分心智游移和专注注意的非线性脑电图分析：一种机器学习方法 | Sundaram, S. | N/A | Nonlinear EEG Analysis for Distinguishing Mind Wandering and Focused Attention: A Machine Learning Approach | |
| 数据异质性对临床MALDI-TOF质谱图谱通过机器学习进行直接抗菌药物耐药性预测的影响 | Park, Y. | N/A | Effect of Data Heterogeneity in Clinical MALDI-TOF Mass Spectra Profiles on Direct Antimicrobial Resistance Prediction through Machine Learning | |
| 中风会损害在可预测跑步机加速过程中对动态平衡的主动控制 | Cornwell, T. I. | N/A | Stroke impairs the proactive control of dynamic balance during predictable treadmill accelerations | |
| 通过冷冻电镜断层成像技术可视化的AMPA受体支架复合物的原位结构和形貌 | Held, R. G. | N/A | In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET | |
| MEGF10在肌细胞融合和骨骼肌超负荷肥大反应中的作用 | Richardson, L. | N/A | The role of MEGF10 in myoblast fusion and hypertrophic response to overload of skeletal muscle | |
| 稳定性与灵活性：在计算机模拟中重塑单层和双层古菌膜 | Amaral, M. | N/A | Stability vs flexibility: reshaping monolayer and bilayer archaeal membranes in silico | |
| 功能和泛基因组探索Roc双组分调控系统在假单胞菌属中的新角色 | SIMON, V. | N/A | Functional and pangenomic exploration of Roc two-component regulatory systems identifies novel players across Pseudomonas species | |
| 精神分裂症风险基因SETD1A的突变会扰乱人类神经元中的突触功能 | Su, X. | N/A | Mutations of schizophrenia risk gene SETD1A dysregulate synaptic function in human neurons | |
| 封闭杏仁核和古皮质神经元的分子特征及其连接性 | Kaur, N. | N/A | Molecular Specification of Claustro-Amygdalar and Paleocortical Neurons and Connectivity | |
| # BioRxiv 2024-10-19 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 通过测量神经活动进行效用的个体间比较 | Matsumori, K. | N/A | Interpersonal Comparison of Utility by Measuring Neural Activity | |
| RatXcan：一种用于跨物种整合全基因组关联和基因表达数据的框架 | Santhanam, N. | N/A | RatXcan: A framework for cross-species integration of genome-wide association and gene expression data | |
| 生活方式塑造了真菌病原体的基因组大小和基因含量 | Fijarczyk, A. | N/A | Lifestyles shape genome size and gene content in fungal pathogens | |
| 鸣禽发声模仿的传感器运动回路的突触连接 | Trusel, M. | N/A | Synaptic Connectivity of Sensorimotor Circuits for Vocal Imitation in the Songbird | |
| 拟南芥根尖（V2）中tRNASer/tRNATyr基因簇的转录再激活 | Hummel, G. | N/A | Transcriptional reactivation of the tRNASer/tRNATyr gene cluster in Arabidopsis thaliana root tip (V2) | |
| 分子伴侣的局部合成维持了神经元的蛋白质稳态 | Alecki, C. | N/A | Localized synthesis of molecular chaperones sustains neuronal proteostasis | |
| 在人类类器官中以细胞类型为重点的化合物筛选揭示了CK1和MAPK11的抑制保护视锥光感受器免于死亡 | Spirig, S. E. | N/A | Cell type-focused compound screen in human organoids reveals CK1 and MAPK11 inhibition protects cone photoreceptors from death | |
| 光纤光度实验中试验级时间动态分析的统计框架 | Loewinger, G. | N/A | A Statistical Framework for Analysis of Trial-Level Temporal Dynamics in Fiber Photometry Experiments | |
| 分层运动感知作为因果推断 | Shivkumar, S. | N/A | Hierarchical motion perception as causal inference | |
| 衰老过程中细胞外基质的重塑与突触、小胶质细胞及认知状态相一致 | Gray, D. T. | N/A | Extracellular matrix remodeling during aging aligns with synapse, microglia, and cognitive status | |
| 对皮层内和皮层-丘脑模型中的阿尔法节律进行了全面调查 | Bastiaens, S. P. | N/A | A comprehensive investigation of intracortical and corticothalamic models of alpha rhythms | |
| RNAinformer：结合三级相互作用的生成性RNA设计 | Patil, S. | N/A | RNAinformer: Generative RNA Design With Tertiary Interactions | |
| 慢性乙醇暴露会导致纹状体中认知灵活性和决策信号的持续损伤 | Cheng, Y. | N/A | Chronic Ethanol Exposure Produces Persistent Impairment in Cognitive Flexibility and Decision Signals in the Striatum | |
| 基底神经节输出 - 内顶核 - 自由活动小鼠中对情境运动学和奖励的编码 | Verma-Rodriguez, A. K. | N/A | Basal ganglia output - entopeduncular nucleus - coding of contextual kinematics and reward in the freely moving mouse | |
| 发展性语言障碍（DLD）儿童对节奏性言语的神经处理：一项脑电图研究 | Keshavarzi, M. | N/A | Neural processing of rhythmic speech by children with developmental language disorder (DLD): An EEG study | |
| 通过全基因组测序揭示巴基斯坦山羊中斯氏毛圆线虫的群体遗传学 | Afshan, K. | N/A | The population genetics of Strongyloides papillosus in Pakistani goats revealed by whole genome sequencing | |
| 豌豆（Pisum sativum）在根瘤层面会对效果较差的菌株实施限制，但不会在混合根瘤中进行。 | Underwood, T. J. | N/A | Pisum sativum applies sanctions to less effective strains at the nodule level, but not within mixed nodules | |
| 利用功能磁共振成像任务对人类听觉和视觉丘脑进行功能定位 | Williams, J. C. | N/A | Functional Localization of the Human Auditory and Visual Thalamus Using a Thalamic Localizer Functional Magnetic Resonance Imaging Task | |
| 利用历史偶然进展选择基因进行分析：从RNA变化到蛋白质相互作用 | Lalit, F. | N/A | Selecting genes for analysis using historically contingent progress: from RNA changes to protein-protein interactions | |
| 钙调蛋白/C16orf74中的一种新基序决定了通过钙调神经磷酸酶进行的聚合脱磷酸化 | Bradburn, D. A. | N/A | A novel motif in calcimembrin/C16orf74 dictates multimeric dephosphorylation by calcineurin | |
| 使用诱捕法评估串联质谱分析中的假发现率控制 | Wen, B. | N/A | Assessment of false discovery rate control in tandem mass spectrometry analysis using entrapment | |
| 通过水平转移，pMAB625质粒编码的MMPL家族转运蛋白在全球范围内传播于耐多药的脓肿分枝杆菌临床分离株中。 | Ohse, K. | N/A | Worldwide spreading of pMAB625 plasmid encoding MMPL family transporter in multidrug-resistant clinical isolates of Mycobacterium abscessus by horizontal transfer | |
| 口服万古霉素治疗改变了吲哚衍生物和次级胆酸的水平，这些变化调节了在实验性自身免疫性脑脊髓炎（EAE）期间星形胶质细胞中mTOR通路基因的表达。 | Bianchimano, P. | N/A | Oral vancomycin treatment alters levels of indole derivatives and secondary bile acids modulating the expression of mTOR pathway genes in astrocytes during EAE | |
| 迈向更客观且高通量的球体侵袭实验定量方法 | Mungai, R. W. | N/A | Towards a More Objective and High-throughput Spheroid Invasion Assay Quantification Method | |
| 一种用于皮质抑制时间多样性的树突状基质 | Morabito, A. | N/A | A dendritic substrate for temporal diversity of cortical inhibition | |
| 果蝇幼虫和成虫中枢神经系统中iPLA2-VIA基因表达的分析 | Moura, G. | N/A | Analysis of iPLA2-VIA Gene Expression in The CNS of Larvae and Adult Drosophila Melanogaster Flies | |
| 评估高致病性禽流感H5病毒在法国肉鸡和蛋鸡生产网络中传播的风险 | Hautefeuille, C. | N/A | Assessing the risk of highly pathogenic avian influenza H5 viruses spread within French broiler and layer production networks | |
| 一个依赖于气候和人口的扩散模型预测了白纹伊蚊在欧洲的传播情况。 | Barman, S. | N/A | A climate and population dependent diffusion model forecasts the spread of Aedes Albopictus mosquitoes in Europe | |
| 在广泛共识的基础上，开发并详细测序了一对匹配的肿瘤-正常基因组瓶对。 | McDaniel, J. H. | N/A | Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair | |
| 插入偏倚对piRNA簇的影响及其对转座元件入侵的影响 | Pritam, S. | N/A | The impact of insertion bias into piRNA clusters on the invasion of transposable elements | |
| 已发表的兔核糖体rRNA序列中的不一致性：关于序列和位点编号统一性的建议 | De, S. | N/A | Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering | |
| 结构和功能证据支持将小鼠的高级视觉区域重新定义为单一的V2区域。 | Rowley, D. P. | N/A | Structural and functional evidence supports re-defining mouse higher order visual areas into a single area V2 | |
| 孢粉素生物合成中的聚酮途径是陆地植物（胚胎植物门）所特有的。 | Sraan, D. K. | N/A | The polyketide pathway in sporopollenin biosynthesis is specific to land plants (Embryophyta) | |
| 大多数L1CAM并不与人类生物液体和诱导多能干细胞衍生的神经元中的细胞外囊泡相关联。 | Kadam, V. | N/A | Most L1CAM is not associated with extracellular vesicles in human biofluids and iPSC-derived neurons | |
| 多样化的祖先揭示了真核起源期间复杂的共生相互作用 | Bernabeu, M. | N/A | Diverse ancestries reveal complex symbiotic interactions during eukaryogenesis | |
| 自闭症中白质微观结构改变的局部化与束分析 | Kim, G. S. | N/A | White Matter Microstructural Alterations in Autism Localized with Bundle Analytics | |
| 脆性X综合征的iPSC模型反映了临床表型，并揭示了m6A介导的表观转录组失调，这种失调是突触功能障碍的基础。 | Guo, Z. | N/A | An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m6A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction | |
| 联邦深度学习通过蛋白质组学实现癌症亚型分类 | Cai, Z. | N/A | Federated deep learning enables cancer subtyping by proteomics | |
| 艺术的隐藏拓扑结构：窥探人类感知的一扇窗 | Dmitruk, E. | N/A | Art's Hidden Topology: A window into human perception | |
| 艺术中的隐藏拓扑结构：窥探人类感知的一扇窗 | Dmitruk, E. | N/A | Art's Hidden Topology: A window into human perception | |
| 基于代理的拟南芥合子中皮质微管带运动的模拟 | Nonoyama, T. | N/A | Agent-Based Simulation of Cortical Microtubule Band Movement in the Arabidopsis Zygote | |
| Spectrin协调皮质肌动肌球蛋白的组织和分化，这对功能性上皮屏障至关重要。 | Soffer, A. | N/A | Spectrin coordinates cortical actomyosin organization and differentiation essential for a functional epithelial barrier | |
| 揭示隐藏威胁：通过DNA条形码技术探索毛里塔尼亚班克·阿尔金国家公园（PNBA）中的海洋无脊椎动物入侵 | Moura, C. J. | N/A | Revealing Hidden Threats: Marine Invertebrate Invasions in the Banc d'Arguin National Park (PNBA), Mauritania, Explored Through DNA Barcoding | |
| 人类和非人类灵长类动物杏仁核亚区转录组多样性 | Totty, M. S. | N/A | Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates | |
| 在大规模外排敲除系统中确定铜绿假单胞菌MexXY-OprM特异性揭示了不同的抗生素底物类别 | Kavanaugh, L. G. | N/A | Determination of Pseudomonas aeruginosa MexXY-OprM specificity in a major efflux knockout system reveals distinct antibiotic substrate classes | |
| 在大规模排出敲除系统中确定铜绿假单胞菌MexXY-OprM特异性揭示了不同的抗生素底物类别 | Kavanaugh, L. G. | N/A | Determination of Pseudomonas aeruginosa MexXY-OprM specificity in a major efflux knockout system reveals distinct antibiotic substrate classes | |
| 转谷氨酰胺酶2依赖的H3K4me3的丝氨酰化对RIPK3的表观遗传调控影响坏死性凋亡 | Vecchio, A. | N/A | Epigenetic modulation of RIPK3 by Transglutaminase 2-dependent serotonylation of H3K4me3 affects necroptosis | |
| 人类参考iPSC系KOLF2.1J的光学基因组图谱揭示了神经发育基因中的新型较小结构变异 | Yang, M. J. | N/A | Optical Genome Mapping of the human reference iPSC line KOLF2.1J reveals new smaller structural variants in neurodevelopmental genes | |
| 人类谱系的深层合并历史 | Cousins, T. | N/A | Deep coalescent history of the hominin lineage | |
| 无需全基因组测序即可确定肿瘤中人乳头瘤病毒整合的新型纳米孔测序方法 | Parida, P. | N/A | Novel nanopore sequencing method for determining Human Papillomavirus integrations in tumors without the need for whole genome sequencing | |
| 剖析由串联RNA结合结构域介导的RNA选择性 | Harris, S. E. | N/A | Dissecting RNA Selectivity Mediated by Tandem RNA-Binding Domains | |
| 通过高通量蛋白质组学实现对脑蛋白新底物景观的无偏映射 | Rankovic, Z. | N/A | Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics | |
| 利用SPARCE技术对低细胞数量进行多重磷酸蛋白质组学分析 | Gaizley, E. J. | N/A | Multiplexed phosphoproteomics of low cell numbers using SPARCE | |
| PINK1介导的泛素磷酸化水平升高有助于蛋白酶体功能障碍，并促进神经退行性变。 | Chen, C. | N/A | Elevated Ubiquitin Phosphorylation by PINK1 Contributes to Proteasomal Impairment and Promotes Neurodegeneration | |
| CelFDrive：人工智能辅助显微镜技术，用于稀有事件的自动化检测 | Brooks, S. | N/A | CelFDrive: Artificial Intelligence assisted microscopy for automated detection of rare events | |
| 系统性锕-225阿尔法粒子树状放射偶联物治疗胶质母细胞瘤的效果通过化疗得到改善 | Nair, R. R. | N/A | Glioblastoma Treatment by Systemic Actinium-225 alpha-particle Dendrimer-radioconjugates is Improved by Chemotherapy | |
| 感染卡波西肉瘤相关疱疹病毒的内皮细胞显示出独特的黏弹性和形态特征。 | Shabangu, M. M. | N/A | Endothelial cells infected with Kaposi's sarcoma-associated herpesvirus display distinct viscoelasticity and morphology | |
| 牙买加果蝠（Artibeus jamaicensis）对埃博拉病毒而非马尔堡病毒的易感性，是由病毒进入宿主细胞和干扰素I型信号通路拮抗作用的内源性差异所驱动的。 | Van Tol, S. | N/A | Jamaican fruit bats (Artibeus jamaicensis) competence for Ebola virus but not Marburg virus is driven by intrinsic differences in viral entry and IFN-I signaling antagonism. | |
| 暂停的聚合酶与转录因子及RNA协同作用，增强启动子的转录潜力 | Mann, R. | N/A | Paused Polymerase synergises with transcription factors and RNA to enhance the transcriptional potential of promoters | |
| Setdb1通过抑制允许性染色质结构和转录变异性，调控成年肠道干细胞的正常分化。 | Talianidis, I. | N/A | Setdb1 regulates proper differentiation of adult intestinal stem cells via restraining permissive chromatin structure and transcriptional variability | |
| TRIM24通过染色质信号传导指导复制应激反应，以维持ALT端粒 | Kim, D. | N/A | TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling | |
| 电趋化作用破坏了体外培养的人角膜上皮细胞的细胞间相互作用模式 | Crossley, R. M. | N/A | Electrotaxis disrupts patterns of cell-cell interactions of human corneal epithelial cells in vitro | |
| 监测溶酶体降解：评估细胞外蛋白靶向溶酶体降解的敏感探针 | Holly, R. W. | N/A | Monitoring lysosomal catabolism: a sensitive probe for assessing targeted lysosomal degradation of extracellular proteins | |
| Wnt 特异性诱导 FZD5/8 的内吞和降解，并涉及 RSPO-ZNRF3/RNF43 和 DVL 的作用。 | Luo, D. | N/A | Wnt specifically induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL | |
| SNAI2与MEK1/2和HDACs合作，抑制TERT启动子突变癌症中依赖BIM和BMF的凋亡。 | Tandon, A. | N/A | SNAI2 cooperates with MEK1/2 and HDACs to suppress BIM- and BMF-dependent apoptosis in TERT promoter mutant cancers | |
| 下丘脑电路机制对压力影响记忆和睡眠的作用 | Wiest, A. | N/A | A hypothalamic circuit mechanism underlying the impact of stress on memory and sleep | |
| 人类牙髓干细胞向具有电生理活性的神经样细胞的功能性分化 | Pardo-Rodriguez, B. | N/A | Functional differentiation of Human Dental Pulp Stem Cells into neuron-like cells exhibiting electrophysiological activity | |
| TORC2调控的固醇类物质再分布介导了由小分子两亲性物质引起的膜扰动后的恢复过程。 | Tettamanti, M. G. | N/A | TORC2-regulated sterol redistribution mediates recovery from membrane perturbation by small amphipathic molecules. | |
| IVF患者和卵子捐赠者的生殖道微生物群：一项比较分析 | Haahr, T. | N/A | The genital tract microbiota of IVF patients and oocyte donors: a comparative analysis | |
| 对肺炎链球菌细胞壁中磷壁酸的新评估 | Mai, N. | N/A | New assessment of teichoic acids in the cell envelope of Streptococcus pneumoniae | |
| Bicra/Gltscr1的缺失导致小鼠胎儿肝脏中负责红细胞成熟的巨噬细胞功能缺陷。 | Sood, S. | N/A | Loss of Bicra/Gltscr1 leads to a defect in fetal liver macrophages responsible for erythrocyte maturation in mice. | |
| Zebrahub-Multiome：揭示斑马鱼胚胎发育过程中基因调控网络的动态变化 | Kim, Y. J. | N/A | Zebrahub-Multiome: Uncovering Gene Regulatory Network Dynamics During Zebrafish Embryogenesis | |
| 拟南芥花药中生殖细胞的机械调控 | Liu, C. | N/A | Mechanical control of germ cell specification in Arabidopsis anthers | |
| Shh信号在再生中的X. tropicalis脊髓中指导背腹分化 | Angell Swearer, A. | N/A | Shh signaling directs dorsal ventral patterning in the regenerating X. tropicalis spinal cord | |
| 景天科伽蓝菜属（Kalanchoe）的新系统发育框架及其对属下分类的启示 | Rodewald, S. E. | N/A | A new phylogenetic framework for the genus Kalanchoe (Crassulaceae) and implications for infrageneric classification | |
| 在脂质生成型三阴性乳腺癌细胞中，四环素转录激活受到破坏。 | Townsel, A. | N/A | Tet Transgene Activation is Disrupted in Lipogenic Triple Negative Breast Cancer Cells | |
| 通过分离相分离调控合成细胞内的生物冷凝物 | Chen, C. | N/A | Regulating biocondensates within synthetic cells via segregative phase separation | |
| SARS-CoV-2 Mpro中的奈玛特韦耐药突变通过切割NF-κB必需调节因子增强宿主免疫逃避 | Thomas, M. | N/A | Nirmatrelvir-Resistant Mutations in SARS-CoV-2 Mpro Enhance Host Immune Evasion via Cleavage of NF-κB Essential Modulator | |
| 叶菜类蔬菜的栽培条件决定了叶际细菌群落结构，并最终影响李斯特菌在采后阶段的生长。 | Culliney, P. | N/A | Cultivation conditions of leafy vegetables determine phyllosphere bacterial community structures and ultimately affect growth of L. monocytogenes post-harvest | |
| 识别并减轻血液对AgNbO3颗粒抗菌活性的干扰 | Talebpour, C. | N/A | Identification and mitigation of blood's interference with the antimicrobial activity of AgNbO3 particles | |
| 发现广谱细菌多胺解毒抑制剂作为潜在的抗毒力剂和抗生素佐剂 | Moulding, P. B. | N/A | Discovery of broad-spectrum bacterial polyamine detoxification inhibitors as potential antivirulence agents and antibiotic adjuvants | |
| 脊髓灰质炎病毒的非裂解性传播需要非结构蛋白3CD的参与。 | Aponte-Diaz, D. | N/A | Non-lytic spread of poliovirus requires the nonstructural protein 3CD | |
| 宿主内动态，连同基因型和表型效应，共同预测病毒突变的成功与否。 | Tan, C. C. S. | N/A | Intrahost dynamics, together with genetic and phenotypic effects predict the success of viral mutations | |
| Hsp90抑制剂结合的动态洞察：揭示中间态与构象可塑性 | Sahil, M. | N/A | Dynamic Insights into Hsp90 Inhibitor Binding: Uncovering Intermediate States and Conformational Plasticity | |
| PDZ激酶变构中继介导Par复合物调节剂交换 | Vargas, E. | N/A | A PDZ-kinase allosteric relay mediates Par complex regulator exchange | |
| Drp1介导的线粒体分裂保护巨噬细胞免受mtDNA/ZBP1介导的无菌性炎症，并抑制心肌梗死后心脏重塑。 | Kondo, Y. | N/A | Drp1-mediated mitochondrial fission protects macrophages from mtDNA/ZBP1-mediated sterile inflammation and inhibits post-infarct cardiac remodeling | |
| 促进脂多糖被合成脂滴吸收的因素 | Arnob, A. | N/A | Factors Promoting Lipopolysaccharide Uptake by Synthetic Lipid Droplets | |
| 甲硫基烷烃还原酶利用固氮酶金属簇进行碳硫键的断裂。 | Lago-Maciel, A. | N/A | Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage | |
| 利用人工启动子、RNA适体和深度测序技术进行Sigma因子DNA结合序列的高分辨率绘图 | Khan, E. A. | N/A | High-resolution mapping of Sigma Factor DNA Binding Sequences using Artificial Promoters, RNA Aptamers and Deep Sequencing | |
| CRISPR-Cas9核糖核蛋白的包装递送加速了基因组编辑 | Karp, H. | N/A | Packaged delivery of CRISPR-Cas9 ribonucleoproteins accelerates genome editing | |
| 氨基酸竞争塑造了鲍曼不动杆菌肠道携带 | Ren, X. | N/A | Amino acid competition shapes Acinetobacter baumannii gut carriage | |
| 血吸虫感染对光滑双脐螺螺类微生物群的影响有限 | Nordmeyer, S. | N/A | Limited Impact of Schistosome Infection on Biomphalaria glabrata Snail Microbiomes | |
| YebC2 解决了多聚脯氨酸处的核糖体停滞问题，与 EF-P 和 ABCF ATPase YfmR 无关。 | Hong, H.-R. | N/A | YebC2 resolves ribosome stalling at polyprolines independent of EF-P and the ABCF ATPase YfmR | |
| 一个信封应激反应通过一个小RNA调控长链脂肪酸代谢，以维持大肠杆菌中的氧化还原稳态。 | Shrivastava, M. | N/A | An envelope stress response governs long-chain fatty acid metabolism via a small RNA to maintain redox homeostasis in Escherichia coli | |
| 从马来西亚环境中分离和鉴定降解聚(3HB)的细菌 | Zahra, U. | N/A | Isolation and Identification of P(3HB)-Degrading Bacteria from Malaysian Environment | |
| 甲氧西林抗性对1株金黄色葡萄球菌毒力因子表达的影响：基于基因表达谱的见解 | Gharsallah, C. | N/A | Impact of methicillin resistance on virulence factor expression in 1 Staphylococcus aureus: Insights from gene expression profiling | |
| 一种分布于植物共生细菌中的排出泵家族，能够条件性地对宿主特异性硫代葡萄糖苷进行宿主和器官特异性的解毒。 | Russ, D. | N/A | An efflux pump family distributed across plant commensal bacteria conditions host- and organ-specific detoxfication of a host-specific glucosinolate | |
| 依赖磷酸化的mRNA脱腺苷化速率调控 | Stowell, J. A. | N/A | Phosphorylation-dependent tuning of mRNA deadenylation rates | |
| 类组织多细胞发育由古菌中的机械压缩触发 | Rados, T. | N/A | Tissue-Like Multicellular Development Triggered by Mechanical Compression in Archaea | |
| 放弃四极杆用于质谱碎片分析：通过高分辨率离子迁移前体隔离实现1,000赫兹速度与100%离子利用率 | DeBord, D. | N/A | Abandoning the Quadrupole for Mass Spectrometry Fragmentation Analysis: Towards 1,000 Hz Speeds with 100% Ion Utilization Using High Resolution Ion Mobility Precursor Isolation | |
| 通过丝氨酸整合酶BxbI显著增强人类多能干细胞中的转基因整合 | Autio, M. I. | N/A | Highly enhanced transgene integration in human pluripotent stem cells by serine integrase BxbI | |
| # BioRxiv 2024-10-18 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 刺激前大规模功能连接的动态变化决定了多感官任务中的表现 | Galindo Leon, E. E. | N/A | Dynamic changes in large-scale functional connectivity prior to stimulation determine performance in a multisensory task | |
| 从单细胞和空间转录组学揭示的结直肠癌中空间定义的多细胞功能单元 | Avraham-Davidi, I. | N/A | Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics | |
| 一种含有催产素阳性物质的腰脊髓神经元群体调节性兴奋和交配行为。 | Lenschow, C. | N/A | A galanin-positive population of lumbar spinal cord neurons modulates sexual arousal and copulatory behavior | |
| 脂质稳态受损通过ESCRT破坏导致溶酶体内源性蛋白聚集体的积累 | Yong, J. | N/A | Impairment of lipid homeostasis causes lysosomal accumulation of endogenous protein aggregates through ESCRT disruption | |
| 老化大脑中广泛的不确定性调整抑制 | Kosciessa, J. Q. | N/A | Broadscale dampening of uncertainty adjustment in the aging brain | |
| 通过肽距离分析评估TCR结合预测器的泛化能力 | Castorina, L. V. | N/A | Assessing the Generalization Capabilities of TCR Binding Predictors via Peptide Distance Analysis | |
| 一种可调的极简细胞膜揭示出，两种脂质种类足以维持生命 | Justice, I. G. | N/A | A tuneable minimal cell membrane reveals that two lipid species suffice for life | |
| 从自拍到科学 - 使用iPhone 13进行精确的3D叶片测量及其对植物发育和蒸腾作用的启示 | Bar-Sella, G. | N/A | From Selfies to Science - Precise 3D Leaf Measurement with iPhone 13 and Its Implications for Plant Development and Transpiration | |
| RmlT是一种调节李斯特菌单胞菌毒力的壁磷壁酸鼠李糖基转移酶的分子特性。 | Monteiro, R. | N/A | Molecular properties of RmlT, a wall teichoic acid rhamnosyltransferase that modulates virulence in Listeria monocytogenes. | |
| 在动物的近亲之一中，由盐度引发的克隆聚集性多细胞性 | Ros-Rocher, N. | N/A | Clonal-aggregative multicellularity entrained by salinity in one of the closest relative of animals | |
| 在羧基末端结构域内带负电的区域维持了CTCF与DNA的正确结合。 | Liu, L. | N/A | A negatively-charged region within carboxy-terminal domain maintains proper CTCF DNA binding | |
| 通过基因调控表型鉴定出的丹尼索瓦人候选化石 | Mishol, N. | N/A | Candidate Denisovan fossils identified through gene regulatory phenotyping | |
| 预测帕金森病中病理学性丘脑底核β爆发的发生 | Abdi-Sargezeh, B. | N/A | Prediction of pathological subthalamic nucleus beta burst occurrence in Parkinson's disease | |
| 前胫骨平移产生的大量制动力可诱导小鼠前十字韧带的自发性愈合 | Saito, R. | N/A | Substantial Braking Force of Anterior Tibial Translation Induces the Spontaneous Healing of Murine Anterior Cruciate Ligament | |
| 刺激前β波功率在不同皮质区域介导显性和隐性知觉偏差 | Forster, C. | N/A | Pre-stimulus beta power mediates explicit and implicit perceptual biases in distinct cortical areas | |
| scCancerExplorer：一个综合数据库，用于交互式探索人类泛癌单细胞多组学数据 | Huang, C. | N/A | scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer | |
| 机械拉伸足细胞中的选择性剪接作为肾小球高血压的模型 | Mattias, F. | N/A | Alternative splicing in mechanically stretched podocytes as a model of glomerular hypertension | |
| PA28γ通过提升线粒体功能，促进肿瘤的恶性进展，这一过程涉及C1QBP。 | Wang, J. | N/A | PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP | |
| 利用时间数据对调控内皮屏障完整性的激酶磷酸信号网络进行系统级重构 | Wei, L. | N/A | Systems-level reconstruction of kinase phosphosignaling networks regulating endothelial barrier integrity using temporal data | |
| 内在动态在人脑对外部刺激的反应中起着重要作用。 | Nentwich, M. | N/A | Intrinsic dynamic shapes responses to external stimulation in the human brain | |
| 预测无关信息：干扰项可预测性的神经效应取决于认知负荷 | Lui, T. K.-Y. | N/A | Predicting the irrelevant: Neural effects of distractor predictability depend on load | |
| 刺胞动物胚胎中的平面细胞极性协调为动物体轴的进化提供了线索。 | Uveira, J. | N/A | Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution | |
| 定性脑电图异常提示大脑网络向抑制主导型转变。EU-AIMS LEAP研究的结果显示了这一点。 | Juarez-Martinez, E. L. | N/A | Qualitative EEG abnormalities signal a shift towards inhibition-dominated brain networks. Results from the EU-AIMS LEAP studies | |
| 海洋群岛进化辐射的生物地理学 | Bree, B. | N/A | The biogeography of evolutionary radiations on oceanic archipelagos | |
| 解析苯基琥珀酸合酶的对映选择性机制：通过多尺度建模和动力学研究厌氧烃降解的启示 | Szaleniec, M. | N/A | Unravelling the Enantioselective Mechanism of Benzylsuccinate Synthase: Insights into Anaerobic Hydrocarbon Degradation Through Multiscale Modelling and Kinetics | |
| 利用dCas引导的邻近标记技术在曲霉菌中进行位点特异性染色质蛋白质组学研究。 | Svoboda, T. | N/A | Locus-specific chromatin proteomics using dCas-guided proximity labelling in Aspergillus nidulans. | |
| 从动物行为和福利的角度来看，监狱犬训练项目的效果如何？ | Baria-Unwalla, P. | N/A | What's in it for the dogs? Assessing the outcomes of a prison-based dog training program from an animal behavior and welfare perspective | |
| 使用中位数对单细胞DNA甲基化数据中不可用值进行插补，既直接又有效。 | Tang, S. | N/A | Imputing not available values in single-cell DNA methylation data using the median is straightforward and effective | |
| 利用微流控技术、延时相差显微镜和深度学习快速鉴定七种细菌种类 | Hallström, E. | N/A | Rapid identification of seven bacterial species using microfluidics, time-lapse phase-contrast microscopy, and deep learning | |
| 人类星形胶质细胞同步化神经类器官网络 | Patel, M. D. | N/A | Human Astrocytes Synchronize Neural Organoid Networks | |
| FBXW7通过调节MYRF水平来控制成年中枢神经系统中髓鞘的容量和稳态 | Collins, H. Y. | N/A | FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult CNS | |
| 通过组织特异性表达变化实现剂量敏感基因的进化 | Rice, A. M. | N/A | Evolution of dosage-sensitive genes by tissue-restricted expression changes | |
| 暂时性脑缺血损害了血栓素A2的收缩作用，并诱导了高血压大鼠外周肠系膜动脉的肥厚性重塑，尽管长期使用亚油酰胺羟肟酸进行脑保护，但逆转效果有限。 | Diaz-Perez, A. | N/A | Temporary cerebral ischaemia impairs thromboxane A2 constriction and induces hypertrophic remodelling in peripheral mesenteric arteries of hypertensive rats: limited reversal despite long-term suberoylanilide hydroxamic acid cerebroprotection | |
| 抑制PDGFRβ信号增强肌细胞融合以促进骨骼肌再生 | Xue, S. | N/A | Suppressing PDGFRβ Signaling Enhances Myocyte Fusion to Promote Skeletal Muscle Regeneration | |
| 单轴力在青春期发育过程中改变乳腺导管网络的长度和导管的方向：来自计算建模和实验室实验的发现 | George, U. Z. | N/A | Uniaxial force modifies the length of the mammary ductal network and the orientation of ducts during pubertal development: Findings from computational modeling and laboratory experiments | |
| 单轴力在青春期发育过程中改变乳腺导管网络的长度和导管的方向：来自计算建模和实验室实验的发现 | George, U. Z. | N/A | Uniaxial force modifies the length of the mammary ductal network and the orientation of ducts during pubertal development: Findings from computational modeling and laboratory experiments | |
| 在净化选择下的家谱 | Khudiakova, K. A. | N/A | Genealogies under purifying selection | |
| 估计利什曼原虫的有性生殖率和近交率 | Nicoll, A. G. | N/A | Estimating the rate of sexual reproduction and the inbreeding rate in Leishmania | |
| ybx1通过上游调控atoh1a，促进斑马鱼侧线神经丘毛细胞的快速再生。 | Reagor, C. C. | N/A | ybx1 acts upstream of atoh1a to promote the rapid regeneration of hair cells in zebrafish lateral-line neuromasts | |
| 一种谱系特异性新生RNA检测揭示了组织生物学中基因调控的原理 | Chovatiya, G. | N/A | A lineage-specific nascent RNA assay unveils principles of gene regulation in tissue biology | |
| 血小板单细胞转录组的首份全面描述 | Wolfsberger, W. | N/A | The First Comprehensive Description of the Platelet Single Cell Transcriptome | |
| 转录组和文本的多模态学习使得通过自然语言聊天实现单细胞RNA测序数据的交互式探索成为可能。 | Schaefer, M. | N/A | Multimodal learning of transcriptomes and text enables interactive single-cell RNA-seq data exploration with natural-language chats | |
| 在个性化基因组序列上训练深度学习模型可提高变异效应预测的准确性。 | He, A. Y. | N/A | Training deep learning models on personalized genomic sequences improves variant effect prediction | |
| 用区间假设替代归一化方法可提高差异表达和差异丰度分析的严谨性和鲁棒性 | McGovern, K. C. | N/A | Replacing Normalizations with Interval AssumptionsImproves the Rigor and Robustness of DifferentialExpression and Differential Abundance Analyses | |
| 人类拓扑异构酶IIα通过相变促进染色质凝聚 | Wu, M. | N/A | Human Topoisomerase IIα Promotes Chromatin Condensation Via a Phase Transition | |
| CcdA通过共翻译折叠机制保护CcdB免受不可逆错误折叠和聚集。 | Bajaj, P. | N/A | CcdA chaperones CcdB against irreversible misfolding and aggregation via a cotranslational folding mechanism | |
| 无ECM的患者来源类器官保留了多样化的前列腺癌谱系，并揭示了体外富集的细胞类型 | Dolgos, R. | N/A | ECM-free patient-derived organoids preserve diverse prostate cancer lineages and uncover in vitro-enriched cell types | |
| RAS/PI3K通路突变使上皮性卵巢癌细胞对PARP/NAMPT抑制剂组合敏感 | Gruet, M. | N/A | RAS/PI3K pathway mutations sensitise epithelial ovarian cancer cells to a PARP/NAMPT inhibitor combination | |
| 阿尔茨海默病APP/PS1雄性和雌性模型以及APPNL-F/NL-F雄性和雌性模型的寿命 | Roberts, H. | N/A | Lifespan of male and female APP/PS1 and APPNL-F/NL-F mouse models of Alzheimer's disease | |
| 外源硒补充剂可减少镉在稻米中的积累，并恢复稻米中的微量营养素含量。 | Barman, F. | N/A | Exogenous selenium supplements reduce cadmium accumulation and restores micronutrient content in rice grains | |
| 寄生植物的寄生虫在非传统阶段利用开花途径形成茎衍生的虫瘿。 | Bessho-Uehara, K. | N/A | Parasitic-plant parasite utilizes flowering pathways at unconventional stages to form stem-derived galls | |
| 肠道细菌衍生的琥珀酸可诱导肠神经系统再生 | Aydin, B. | N/A | Gut bacteria-derived succinate induces enteric nervous system regeneration | |
| 粘附G蛋白偶联受体ADGRG1促进阿尔茨海默病中保护性小胶质细胞反应 | Zhu, B. | N/A | Adhesion G protein-coupled receptor ADGRG1 promotes protective microglial response in Alzheimer's disease | |
| 内侧前额叶皮层中的下边缘区，而非前边缘区，对于复杂的嗅觉记忆任务是必需的。 | Jun, D. J. | N/A | The infralimbic, but not the prelimbic cortex is needed for a complex olfactory memory task. | |
| 神经肽动态协调分层可塑性机制，使果蝇昼夜节律行为适应变化的环境。 | Chatterjee, A. | N/A | Neuropeptide Dynamics Coordinate Layered Plasticity Mechanisms Adapting Drosophila Circadian Behavior to Changing Environment. | |
| 整合时间进程分析：来自携带C9orf72、FUS、TARDBP和SOD1突变的ALS患者的iPSCs衍生运动神经元 | Ma, G. | N/A | Integrated temporal profiling of iPSCs-derived motor neurons from ALS patients carrying C9orf72, FUS, TARDBP, and SOD1 mutations | |
| H3K9me3的表观遗传去抑制通过免疫调节和Vgf诱导缓解了阿尔茨海默病相关病理，并改善了认知功能 | Fuchs, D.-T. | N/A | Epigenetic derepression of H3K9me3 mitigates Alzheimer-related pathology and improves cognition via immunomodulation and Vgf induction | |
| 青光眼视网膜神经节细胞（RGC）死亡与眼压（IOP）诱导的血视网膜屏障破坏有关。 | Zhang, C. | N/A | IOP-induced blood-retinal barrier compromise contributes to RGC death in glaucoma | |
| 胶质细胞衍生的通路引导再生视神经轴突向中枢神经系统中线方向生长。 | Harvey, B. M. | N/A | Glial cell derived pathway directs regenerating optic nerve axons toward the CNS midline | |
| 腹内侧前额叶皮层的独特神经过程介导了注意力负荷的变化和尼古丁促进认知效应的作用 | Vouillac-Mendoza, C. | N/A | Distinct neuronal processes in the ventromedial prefrontal cortex mediate changes in attention load and nicotine pro-cognitive effects | |
| 感觉运动整合增强了温度刺激的处理能力 | Anderson, L. S. | N/A | Sensorimotor integration enhances temperature stimulus processing | |
| 糖酵解抑制功能性重编程T滤泡辅助细胞并逆转狼疮 | Elshikha, A. | N/A | Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus | |
| 人类抗糖基化反应是由B细胞的选择驱动的，这些B细胞利用了在生发中心中亲和力成熟的私人抗体基因重排。 | New, J. S. | N/A | Human Anti-Glycan Reactivity is Driven by the Selection of B cells Utilizing Private Antibody Gene Rearrangements that are Affinity Maturated in Germinal Centers | |
| 一种来自激活的CD4 T细胞的外泌体资源，用于传递促炎信号 | Jainarayanan, A. K. | N/A | A resource for extracellular vesicles from activated CD4 T cells that relay pro-inflammatory signals | |
| CD4+ T细胞中G蛋白信号调节因子2敲除促进抗炎T细胞，增强排卵和卵母细胞产量 | Raff, M. | N/A | Regulator of G-Protein Signaling 2 Knockout in CD4+ T Cells Promotes Anti-Inflammatory T Cells, Enhancing Ovulation, and Oocyte Yield | |
| 全球RNA病毒组潜在辅助代谢基因（AMGs）的功能和进化特征 | Zhao, Y. | N/A | Functional and evolutionary characterization of potential auxiliary metabolic genes (AMGs) of the global RNA virome | |
| 佛罗里达灌木丛中地衣多样性和丰度调查：与烧伤恢复各个时间阶段的关系 | Holst, M. M. | N/A | Survey of Lichen Diversity and Abundance in a Florida Scrub in Relation to Various Temporal Stages of Burn Recovery | |
| NicheFlow：迈向物种分布建模的基础模型 | Dinnage, R. | N/A | NicheFlow: Towards a foundation model for Species Distribution Modelling | |
| 应用基于发生概率的贝叶斯模型评估环境梯度对塞拉多溪流中水生昆虫属种更替的影响 | Godoy, B. S. | N/A | Application of a Bayesian model based on probability of occurrence to evaluate the effect of an environmental gradient on the turnover of aquatic insect genera in Cerrado streams | |
| 表观基因组的趋同进化在生命之树中招募了DNA修复 | Monroe, G. | N/A | Convergent evolution of epigenome recruited DNA repair across the Tree of Life | |
| 贝克尔肌营养不良症小鼠表现出骨骼肌中IIa型纤维的部位特异性退化，并伴有毛细血管变化。 | Miyazaki, D. | N/A | Becker muscular dystrophy mice showed site-specific decay of type IIa fibers with capillary change in skeletal muscle | |
| 稳定选择和适应塑造了秀丽隐杆线虫中顺式和反式基因表达变异 | Bell, A. D. | N/A | Stabilizing selection and adaptation shape cis and trans gene expression variation in C. elegans | |
| 重建真核生物中RNA结合蛋白的序列特异性 | Sasse, A. | N/A | Reconstructing the sequence specificities of RNA-binding proteins across eukaryotes | |
| 微小RNA 7975直接调控MDTH表达，并在早期动脉粥样硬化的发展中介导内皮细胞的增殖和迁移。 | Karere, G. | N/A | Micro-RNA 7975 directly regulates MDTH expression and mediates endothelial cell proliferation and migration in the development of early atherosclerosis | |
| 可遗传的非遗传表型在压力反应中富集，作为对冲的一种形式。 | Grissom, S. | N/A | Heritable non-genetic phenotypes are enriched for stress responses as a form of bet hedging | |
| 通过共价纳米孔检测实现挥发性有机化合物的高分辨率靶向传感 | McGivern, L. E. | N/A | Targeted, high-resolution sensing of volatile organic compounds by covalent nanopore detection | |
| 从牛胚胎干细胞生成培养牛肉 | Rui, X. | N/A | Generation of cultured beef from bovine embryonic stem cells | |
| 快速单细胞基质辅助激光解吸电离成像技术揭示低分子量代谢物的细胞激活标志物 | Cairns, J. L. | N/A | Fast Single-Cell MALDI Imaging of Low-Mass Metabolites Reveals Cellular Activation Markers | |
| 通过减法蛋白质组学揭示D-丙氨酸-D-丙氨酸连接酶作为伯克霍尔德菌假单胞菌药物靶点的潜力 | Rahman, S. | N/A | Subtractive proteomics unravel the potency of D-Alanine-D-Alanine Ligase as the drug target for Burkholderia pseudomallei | |
| 利用单细胞RNA测序图谱进行抗体面板的交互设计与验证 | Watson, M. | N/A | Interactive design and validation of antibody panels using single-cell RNA-seq atlases | |
| CELL-Diff：统一扩散建模用于蛋白质序列和显微镜图像 | Zheng, D. | N/A | CELL-Diff: Unified diffusion modeling for protein sequences and microscopy images | |
| Carafe能够为数据非依赖性采集蛋白质组学生成高质量的计算机模拟光谱库。 | Wen, B. | N/A | Carafe enables high quality in silico spectral library generation for data-independent acquisition proteomics | |
| 利用AlphaFold2探索电压门控钠通道的构象及蛋白质-蛋白质相互作用 | Mateos, D. L. | N/A | Exploring voltage-gated sodium channel conformations and protein-protein interactions using AlphaFold2 | |
| HP1a促进染色质流动性并驱动自发异染色质区室化 | Brennan, L. D. | N/A | HP1a promotes chromatin liquidity and drives spontaneous heterochromatin compartmentalization | |
| 渗透型临界阈值控制着免疫蛋白对表面的覆盖 | Wang, Z. | N/A | A percolation-type criticality threshold controls immune protein coating of surfaces | |
| 在转录过程中，染色质缓冲扭转应力 | Qian, J. | N/A | Chromatin Buffers Torsional Stress During Transcription | |
| 基于负载的差异在两个识别相同pMHC的TCR的动态别构效应中 | Chang-Gonzalez, A. C. | N/A | Load-based divergence in the dynamic allostery of two TCRs recognizing the same pMHC | |
| 在冷冻电子断层扫描技术下观察到的病毒相关流感血凝素在结合唾液酸后形成的簇状结构 | Huang, Q. Y. | N/A | Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryo-electron tomography | |
| 每周吸入沙美特罗西那非，一种选择性β2肾上腺素受体激动剂药物，在体内治疗性地抑制癌症生长并延长生存期。 | She, X. | N/A | Weekly inhaled salmeterol xinafoate, a selective β2 adrenergic receptor agonist drug, therapeutically inhibits cancer growth and prolongs survival in vivo | |
| 支链氨基酸分解代谢通过mTOR的磷酸化促进卵巢癌细胞增殖 | Lusk, H. J. | N/A | Branched-chain amino acid catabolism promotes ovarian cancer cell proliferation via phosphorylation of mTOR | |
| 氯硝柳胺前药增强口服生物利用度并靶向肝细胞癌中的Vasorin-TGFβ信号通路 | Tan, M. | N/A | Niclosamide Prodrug Enhances Oral Bioavailability and Targets Vasorin-TGFβ Signaling in Hepatocellular Carcinoma | |
| 患者来源的ccRCC肿瘤细胞的长读长空间转录组分析揭示了异构体和基因表达的异质性 | Elshani, M. | N/A | Long-read Spatial Transcriptomic Profiling of Patient-derived ccRCC Tumoroids Reveals Heterogeneity in Isoform and Gene Expression | |
| 肿瘤内CXCL12梯度在乳腺癌中情境化肿瘤细胞侵袭、迁移及免疫抑制 | Anastasiadou, D. P. | N/A | Intratumoral CXCL12 Gradients Contextualize Tumor Cell Invasion, Migration and Immune Suppression in Breast Cancer | |
| 脂质纳米颗粒共递送紫杉醇和大麻二酚增强对黑色素瘤细胞的细胞毒性 | de Carvalho, F. V. | N/A | Co-delivery of Paclitaxel and Cannabidiol in Lipid Nanoparticles Enhances Cytotoxicity Against Melanoma Cells | |
| 印度儿童B细胞急性淋巴细胞白血病患者中CD19外显子5-6跳跃现象普遍存在 | Srivastava, D. | N/A | Widespread Prevalence of CD19 Exon 5-6 Skipping In Indian Pediatric B-cell Acute Lymphoblastic Leukemia Patients | |
| 西酞普兰通过调节C5aR1+肿瘤相关巨噬细胞（TAMs）和CD8+ T细胞，展现出依赖免疫的抗肿瘤效应。 | Dong, F. | N/A | Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs and CD8+ T cells | |
| 速度幅值和周期影响正弦速度变化条件下的步态变异性和步跟随性 | Motoyama, K. | N/A | Speed amplitude and period affect gait variability and step followability under sinusoidal speed changing conditions | |
| 踝跖屈过程中肌腱微振动强度增加的轨迹：使用潜在曲线模型的纵向数据分析 | Matsumoto, T. | N/A | Increase trajectories of tendon micro vibration intensity during ankle plantar flexion: A longitudinal data analysis using latent curve models | |
| 生长素（IAA）及其在复杂轮藻（Chara braunii）中的运输作用 | Kurtovic, K. | N/A | The role of IAA and its transport in the complex streptophyte algae Chara braunii | |
| 黄羽扇豆（Lupinus luteus）对黄羽扇豆炭疽菌（Colletotrichum lupini）的防御机制，涉及TIR-NBS-LRR蛋白、过敏反应及苯丙烷途径 | Godoy, G. A. | N/A | Defense mechanisms in Lupinus luteus against Colletotrichum lupini, involving TIR-NBS-LRR protein, hypersensitive response and phenylpropanoid pathways | |
| 回顾NIP2同源基因在Rhynchosporium spp.复合体中的进化与功能 | Darma, R. | N/A | Revisiting the evolution and function of NIP2 parologs in the Rhynchosporium spp. complex | |
| 转移到不同寄主葡萄藤会导致专食性昆虫Daktulosphaira vitifoliae迅速且广泛地转录可塑性变化 | Collison, W. N. | N/A | Transfer to different host grapevines causes rapid and widespread transcriptional plasticity in the specialist insect Daktulosphaira vitifoliae | |
| 动态多组学与机制建模方法揭示了肾纤维化进展的新机制 | Tuechler, N. | N/A | Dynamic multi-omics and mechanistic modeling approach uncovers novel mechanisms of kidney fibrosis progression | |
| 清醒状态下的蟾蜍大脑活动的慢性记录 | Shaykevich, D. A. | N/A | Chronic recording of brain activity in awake toads | |
| 长期过度活跃引发培养的海马齿状颗粒细胞亚群中大量且持续的氯离子重新分布 | Takano, H. | N/A | Prolonged Hyperactivity Elicits Massive and Persistent Chloride Ion Redistribution in Subsets of Cultured Hippocampal Dentate Granule Cells | |
| 在正常的产后发育过程中，暗色小胶质细胞大量存在，它们通过吞噬作用和细胞穿孔作用重塑突触，并且依赖于TREM2。 | Vecchiarelli, H. A. | N/A | Dark Microglia Are Abundant in Normal Postnatal Development, where they Remodel Synapses via Phagocytosis and Trogocytosis, and Are Dependent on TREM2 | |
| 用于预测小鼠决策过程中神经回路的真实-网络混合神经网络 | Ueoka, Y. | N/A | Real-cyber hybrid neural network for predicting neural circuits in mouse decision-making | |
| 青少年亨廷顿病R6/2小鼠模型中的皮层纹状体发育不良 | Cepeda, C. | N/A | Corticostriatal Maldevelopment in the R6/2 Mouse Model of Juvenile Huntington Disease | |
| 持续注意力期间的警觉性、任务诱发的疲劳和动机：解耦的α波和β波特征的证据 | Hanzal, S. | N/A | EEG markers of vigilance, task-induced fatigue and motivation during sustained attention: Evidence for decoupled alpha- and beta-signatures | |
| 尾索动物布氏菊海鞘（Botryllus schlosseri）中同种识别受体的遗传和功能多样性 | Rodriguez-Valbuena, H. | N/A | Genetic and functional diversity of allorecognition receptors in the urochordate, Botryllus schlosseri | |
| 肺上皮祖细胞介导的TGF-β释放调控黏膜卡介苗接种后肺CD8+ TRM细胞的诱导与持久性 | Blake, J. A. | N/A | Lung epithelial progenitor-mediated release of TGF-β regulates induction and persistence of lung CD8+ TRM cells following mucosal BCG vaccination | |
| 肿瘤内预先存在的干细胞样CD8+ T细胞驱动放射治疗诱导的肿瘤控制 | Koksal, H. | N/A | Pre-existing intratumoral stem-like CD8+ T-cells drive radiotherapy-induced tumor control | |
| 在亚热带海洋生态系统的透光层中，寄生和自养主导的原生生物群落的转换与季节性寡营养-中营养梯度相耦合。 | Avrahami, Y. | N/A | Switch in parasitic and autotrophic-dominated protist assemblages coupled to seasonal oligotrophic-mesotrophic gradients in the sunlit layer of a subtropical marine ecosystem | |
| 一个简单的基于有益和有害相互作用网络的人口动态模型，适用于实证研究。 | Bimler, M. D. | N/A | A simple model of population dynamics with beneficial and harmful interaction networks for empirical applications. | |
| 雌性推动了果蝇物种交配后生殖特征的进化，但并非通过再交配率来实现。 | Peckenpaugh, B. | N/A | Females drive postmating reproductive trait evolution across Drosophila species, but not via remating rate | |
| 身体大小和适应度匹配及其对温度可塑性反应的变异性 | Zygadlo, A. | N/A | The body size and fitness match and its variability in plastic response to temperature | |
| 关岛（马里亚群岛）上两种共存的近缘前礁珊瑚物种的进化基因组学研究。 | Torrado, H. | N/A | Evolutionary genomics of two co-occurring congeneric fore reef coral species on Guam (Mariana Islands). | |
| cGAS-STING通路是基因组不稳定综合征的内源性修饰因子。 | Bergman, M. | N/A | The cGAS-STING pathway is an in vivo modifier of genomic instability syndromes | |
| 利用转录组学研究麦二叉蚜与小麦的相互作用 | Swiegers, H. W. | N/A | Investigating the Diuraphis noxia-Triticum aestivum interaction using transcriptomics | |
| 夜间的人工光照增强了水生碎屑者在捕食风险下的防御行为 | Rufaida, Z. | N/A | Artificial light at night enhances the defensive behavior in aquatic shredders under predation risk | |
| 硫烯素的发现及其新发现的酰基亚硫酸酯功能团的生物合成 | Xue, D. | N/A | Discovery and Biosynthesis of Sulfenicin and Its New-to-Nature Acylsulfenic Acid Functional Group | |
| Du-IN-v2：释放向量量化的力量，从颅内神经信号解码认知状态 | Zheng, H. | N/A | Du-IN-v2: Unleashing the Power of Vector Quantization for Decoding Cognitive States from Intracranial Neural Signals | |
| 从模拟到推断：利用机器学习调整针对特定患者的耳中有限元模型，以实现客观诊断 | Motallebzadeh, H. | N/A | From Simulations to Inference: Using Machine Learning to Tune Patient-Specific Finite-Element Models of the Middle Ear Towards Objective Diagnosis | |
| 天然保湿因子对皮肤保湿的作用，是一个关于氢键网络的故事。 | MARTIN, M. | N/A | Skin hydration by natural moisturizing factors, a story of H-bond networking | |
| 一种综合性的空间多组学工作流程，用于统一分析肿瘤组织 | Kriel, J. | N/A | An integrative spatial multi-omic workflow for unified analysis of tumor tissue | |
| 气溶胶化合物对肺表面活性物质破坏的实验与建模 | Barlow, H. J. | N/A | Experiments and modelling of pulmonary surfactant disruption by aerosolised compounds | |
| 绘制二氢蝶酸合成酶（DHPS）的可进化性图谱：通过进化和结构分析鉴定新型进化关键子结构 | Sanyal, D. | N/A | Mapping DHPS Evolvability: Identification of Novel Evolutionarily Critical Sub-Structure through Evolutionary and Structural Analyses of DHPS | |
| 自愿运动减轻了去势抵抗性前列腺癌临床前模型中的肿瘤生长 | Berger, N. | N/A | Voluntary Exercise Attenuates Tumor Growth in a Preclinical Model of Castration-Resistant Prostate Cancer | |
| 通过FGFR2的消除来拦截导管胰腺癌 | Tonelli, C. | N/A | Ductal pancreatic cancer interception by FGFR2 abrogation | |
| PRMT5介导的组蛋白甲基化通过MECP2-PTBP1调控选择性剪接，促进乳腺癌缺氧环境下的上皮-间质转化（EMT）。 | Mutnuru, S. A. | N/A | PRMT5-mediated histone methylation regulates alternative splicing via MECP2-PTBP1 to promote EMT in breast cancer hypoxia | |
| Path2Space：一种通过组织病理学推断的空间转录组学AI方法用于癌症生物标志物发现 | Shulman, E. D. | N/A | Path2Space: An AI Approach for Cancer Biomarker Discovery Via Histopathology Inferred Spatial Transcriptomics | |
| 通过蛋白质组学解析结直肠癌中的硬度驱动变化 | Cresens, C. | N/A | Deciphering stiffness-driven changes in colorectal cancer by proteomics | |
| 药物蛋白质组学分析鉴定出异常药物作用的分泌标志物 | Knecht, S. | N/A | Pharmacoproteomic profiling identifies secreted markers for aberrant drug action | |
| CCK1受体在小鼠肠道肠肽酶抑制代谢益处中的作用 | Hinke, S. A. | N/A | Role of CCK1 receptor in metabolic benefits of intestinal enteropeptidase inhibition in mice | |
| 冷冻保护剂合成的可塑性涉及从丙酮酸生产中协调分流。 | van der Burg, K. R. L. | N/A | Plasticity in cryoprotectant synthesis involves coordinated shunting away from pyruvate production | |
| 探究棉花CMF基因在盐胁迫耐受性中的作用：来自系统发育、表达和功能分析的见解 | Cui, Y. | N/A | Exploring the Role of Cotton CMF Genes in Salt Stress Tolerance: Insights from Phylogenetic, Expression, and Functional Analyses | |
| 雄性和雌性配子体在冬季相遇：检验日本石栎延迟受精的越冬假说 | Shagawa, T. | N/A | Male and female gametophytes meet after winter: Testing the overwintering hypothesis for delayed fertilization in Japanese stone oak | |
| 植物表型分化在塑造生菜叶微生物群方面比遗传变异更为重要。 | Capparotto, A. | N/A | Plant phenotypic differentiation outweighs genetic variation in shaping the lettuce leaf microbiota | |
| 桃树TNL RMia基因的鉴定与表达，用于抵抗根结线虫Meloidogyne incognita | Duval, H. | N/A | Identification and Expression of the peach TNL RMia genes for the Resistance to the Root-knot Nematode Meloidogyne incognita | |
| 干细胞诱导转录因子WUSCHEL的细胞间移动受运输与保留的平衡调控。 | Fuchs, M. | N/A | Cell-to-cell mobility of the stem cell inducing WUSCHEL transcription factor is controlled by a balance of transport and retention | |
| 气道树的几何分析表明，肺部解剖结构在鲸类动物中进化，以实现爆炸性通气并防止气压伤。 | Cieri, R. | N/A | Geometric analysis of airway trees shows that lung anatomy evolved to enable explosive ventilation and prevent barotrauma in cetaceans | |
| 地下啮齿动物埃洛波斯塔普努斯两个种群的遗传多样性和精细尺度结构 | Rudyk, A. I. | N/A | Genetic diversity and fine-scale structure of two populations of a subterranean rodent, Ellobius talpinus | |
| 一种深度学习方法，用于检测和可视化单型物种中的性二态性 | Silva, N. J. | N/A | A deep learning approach to detect and visualise sexual dimorphism in monomorphic species | |
| 微扫视引起的知觉填充延迟与刺激依赖性 | Levinson, M. | N/A | Stimulus-dependent delay of perceptual filling-in by microsaccades | |
| 长程轴突形态的计算生成 | Berchet, A. | N/A | Computational generation of long-range axonal morphologies | |
| 巨噬细胞与神经前体细胞和成纤维细胞的相互作用通过Sema4ab控制斑马鱼脊髓损伤后的再生性神经发生 | Docampo Seara, A. | N/A | Macrophage crosstalk with neural progenitors and fibroblasts controls regenerative neurogenesis via Sema4ab after spinal cord injury in zebrafish | |
| CXCL10/CXCR3信号通路诱导神经衰老和认知障碍 | Patel, M. | N/A | CXCL10/CXCR3 Signaling Induces Neural Senescence and Cognitive Impairments | |
| 星形胶质细胞Ryk信号在脊髓损伤后协调瘢痕形成和伤口愈合 | Shen, Z. | N/A | Astrocytic Ryk signaling coordinates scarring and wound healing after spinal cord injury | |
| 线粒体不存在于执行监视、趋化性和吞噬性吞噬的微胶质突触中。 | Pietramale, A. N. | N/A | Mitochondria are absent from microglial processes performing surveillance, chemotaxis, and phagocytic engulfment | |
| 通过AP-1调控轴限制先天性Tγδ17细胞的可塑性 | Parker, M. E. | N/A | Restriction of innate Tγδ17 cell plasticity by an AP-1 regulatory axis | |
| 在C. elegans早期胚胎中，Topoisomerase 2/condensin II轴耗竭后的转录组分析。 | Belew, M. D. | N/A | Transcriptome analysis in C. elegans early embryos upon depletion of the Topoisomerase 2/condensin II axis. | |
| 通过海绵组织采集利用环境DNA宏条形码技术研究大型地中海潟湖的空间和季节性生物多样性变化 | Corral-Lou, A. | N/A | Spatial and seasonal biodiversity variation in a large Mediterranean lagoon using environmental DNA metabarcoding through sponge tissue collection | |
| 较弱的neuroligin 2-neurexin 1β相互作用通过聚集锚定膜并促进突触生成 | Boyd, R. | N/A | Weaker neuroligin 2-neurexin 1β interaction tethers membranes and signal synaptogenesis through clustering | |
| 从富含乳糖的废水中生产乳酸：比较反应器配置以最大化转化率和效率的研究 | Temovska, M. | N/A | Lactate production from lactose-rich wastewater: A comparative study on reactor configurations to maximize conversion rates and efficiencies | |
| AI-QuIC：用于种子扩增实验中自动检测错误折叠蛋白质的机器学习 | Howey, K. D. | N/A | AI-QuIC: Machine Learning for Automated Detection of Misfolded Proteins in Seed Amplification Assays | |
| a2iHelper：一个用于RNA-Seq数据差异编辑位点分析的Python工具包 | Ribas, G. T. | N/A | a2iHelper: a Python toolkit for a differential editing site analysis of RNA-Seq data | |
| 通过高浓度聚集调节异源甘氨酸受体功能 | Yu, H. | N/A | Modulation of heteromeric glycine receptor function through high concentration clustering | |
| Src家族激酶抑制剂药物达沙替尼与糖皮质激素联合使用，对舌鳞状细胞癌显示出协同作用，并能降低MET激酶活性。 | Hmedat, A. N. A. | N/A | The Src family kinase inhibitor drug Dasatinib and glucocorticoids display synergistic activity against tongue squamous cell carcinoma and reduce MET kinase activity | |
| 临床来源人体组织数字空间分析的严谨性与可重复性 | Smith, K. D. | N/A | Rigor and Reproducibility of Digital Spatial Profiling on Clinically Sourced Human Tissues | |
| 揭示SH3PXD2B在驱动乳腺癌肺转移的上皮间质转化中的作用 | Das, S. | N/A | Unlocking the role of SH3PXD2B in epithelial-to-mesenchymal transition driving Breast Cancer Lung Metastasis | |
| 睡眠诱导的血管运动脉动是人类大脑中脑脊液和血脑屏障动态变化的一个驱动因素 | Väyrynen, T. | N/A | Sleep-Induced Vasomotor Pulsation is a Driver of Cerebrospinal Fluid and Blood-Brain Barrier Dynamics in the Human Brain | |
| 光遗传学诱导的蛋白质聚集与邻近生物素化测定相结合，强烈暗示内溶酶体蛋白在α-突触核蛋白聚集的早期阶段发挥作用。 | Teixeira, M. | N/A | The combination of optogenetic-induced protein aggregation and proximity biotinylation assays strongly implicates endolysosomal proteins in the early stages of α-synuclein aggregation | |
| 非侵入性光学监测新生儿脑室内出血的临床前模型中的脑血流动力学 | Jethe, J. V. | N/A | Noninvasive optical monitoring of cerebral hemodynamics in a preclinical model of neonatal intraventricular hemorrhage | |
| 通过全面数据分析进行中风结果预测的基准测试 - NeuralCup 2023 | Matsulevits, A. | N/A | Benchmarking Stroke Outcome Prediction through Comprehensive Data Analysis - NeuralCup 2023 | |
| KCNQ2/3 K+通道中功能性与轴突始段运输之间的耦合 | Yoshioka, D. | N/A | Coupling Between Functionality and Trafficking to the Axon Initial Segment in KCNQ2/3 K+ Channels | |
| 神经退行性变小鼠模型和人类疾病中TMEM106B病理的分化与趋同 | Du, M. | N/A | Divergent and Convergent TMEM106B Pathology in Murine Models of Neurodegeneration and Human Disease | |
| 意识的人工智能驱动模型，及其障碍与治疗 | Toker, D. | N/A | An AI-Driven Model of Consciousness, Its Disorders, and Their Treatment | |
| 偏相关作为绘制人脑连接中功能-结构对应关系的工具 | Santucci, F. | N/A | Partial Correlation as a Tool for Mapping Functional-Structural Correspondence in Human Brain Connectivity | |
| 接触含有轮胎和道路磨损颗粒（TRWPs）的城市沉积物复合混合物会增加摇蚊（Chironomus riparius）的种系突变率。 | Rigano, L. | N/A | Exposure to complex mixtures of urban sediments containing Tyre and Road Wear Particles (TRWPs) increases the germ-line mutation rate in Chironomus riparius | |
| 使用机器学习预测天然酵母的表型景观 | Khaiwal, S. | N/A | Predicting the natural yeast phenotypic landscape with machine learning | |
| 非随机交配和环境传播偏差的简单模型对标准人类遗传学统计方法提出了挑战 | Border, R. | N/A | Simple models of non-random mating and environmental transmission bias standard human genetics statistical methods | |
| 甲基化时钟并不能预测基因混合个体的年龄或阿尔茨海默病风险 | Cruz-Gonzalez, S. | N/A | Methylation Clocks Do Not Predict Age or Alzheimer's Disease Risk Across Genetically Admixed Individuals | |
| 小鼠肝脏的昼夜节律异构体图谱 | Zee, A. | N/A | The Circadian Isoform Landscape of Mouse Livers | |
| 雄性和雌性大鼠在平台介导的回避行为中的泛化和消退 | Lppez-Moraga, A. | N/A | Generalization and extinction of platform-mediated avoidance in male and female rats | |
| 为什么蝙蝠会飞进洞穴的门？回声定位动物的注意力缺失性失明 | Finger, N. M. | N/A | Why do bats fly into cave doors? Inattentional blindness in echolocating animals | |
| 初级短跑各阶段影响表现关键因素的演变 | Oku, K. | N/A | Evolution of Key Factors Influencing Performance Across Phases in Junior Short Sprints | |
| 在新热带慈鲷中，面部颜色作为一种社会信号：测试面部表情假说 | Satoh, S. | N/A | Facial Coloration as a Social Signal in a Neotropical Cichlid: Testing the Facial Expression Hypothesis | |
| 利用体外动态力学加载的小鼠后肢培养，实现临界尺寸缺损的胫前肌（TA）再生 | Jacho, D. | N/A | Critical-Size Defect Tibialis Anterior (TA) Muscle Regeneration using Ex-Vivo Mice Hindlimbs Culturing under Dynamic Mechanical Loading | |
| 解析人类视网膜内的发展异质性，以重建视网膜神经节细胞成熟过程的连续性及特定阶段的内在和外在因素 | Kriukov, E. | N/A | Unraveling the developmental heterogeneity within the human retina to reconstruct the continuity of retinal ganglion cell maturation and stage-specific intrinsic and extrinsic factors | |
| 利用特征架构感知的直系同源分配，追踪植物细胞壁降解酶在整个生命树中的分类分布 | Tran, V. | N/A | Tracing the taxonomic distribution of plant cell wall degrading enzymes across the tree of life using feature architecture aware orthology assignments | |
| 一种用于细菌基因组DNA提取和分析的微流控平台 | Joesaar, A. | N/A | A microfluidic platform for extraction and analysis of bacterial genomic DNA | |
| 人类TRPV4工程产生了一种对超声敏感的驱动器，用于声遗传学 | Zhao, L. | N/A | Human TRPV4 engineering yields an ultrasound-sensitive actuator for sonogenetics | |
| 力依赖性重组与机械稳定性：涉及人类受精的Izumo1:Juno复合体的研究 | Boult, S. | N/A | Force-dependent Reorganization and Mechanostability of the Izumo1:Juno Complex Involved in Human Fertilization | |
| 联邦深度学习通过蛋白质组学实现癌症亚型分类 | Cai, Z. | N/A | Federated deep learning enables cancer subtyping by proteomics | |
| 体内CRISPRi筛选鉴定出对皮肤鳞状细胞癌肿瘤生长至关重要的lncRNA组合 | Kim, G. | N/A | In vivo CRISPRi screen identified lncRNA portfolio crucial for cutaneous squamous cell carcinoma tumor growth | |
| TCA循环中的热力学瓶颈导致金黄色葡萄球菌中乙酸的溢出。 | Shahreen, N. | N/A | A thermodynamic bottleneck in the TCA cycle contributes to acetate overflow in Staphylococcus aureus | |
| 热蛋白质组分析揭示了特定细胞区室中氧化还原变化引起的快速蛋白质组反应 | Revazian, A. | N/A | Thermal Proteome Profiling reveals rapid proteomic responses to redox changes in specific cellular compartments | |
| 开发并验证了一个开源的“手性判断任务”，适用于面对面和在线研究 | Moreno-Verdu, M. | N/A | Development and validation of an open-source Hand Laterality Judgement Task for in-person and online studies | |
| 通过机器学习和转录组整合阐明阿尔茨海默病中淀粉样蛋白-β和tau的神经病理学及分子异质性 | Zhao, K. | N/A | Elucidating the neuropathological and molecular heterogeneity of amyloid-beta and tau in Alzheimer's disease through machine learning and transcriptomic integration | |
| 在稳定的选择-反应关联期间，抽象的选择表征 | Quinn, K. R. | N/A | Abstract choice representations during stable choice-response associations | |
| 艺术中的隐秘拓扑：一扇通往人类感知之窗 | Dmitriuk, E. | N/A | Art's Hidden Topology: A window into human perception | |
| 一种针对α-突触核蛋白聚集物的脑穿梭抗体，用于治疗突触核蛋白病 | An, S. | N/A | A brain-shuttled antibody targeting alpha synuclein aggregates for the treatment of synucleinopathies | |
| 对免疫组库数据的统计分析显示了微同源性在V(D)J重组中的影响。 | Russell, M. L. | N/A | Statistical analysis of repertoire data demonstrates the influence of microhomology in V(D)J recombination | |
| 探索硫酸乙酰肝素类似物OTR4120的抗纤维化潜力：来自临床前模型的见解 | Marega, M. | N/A | Exploring the Antifibrotic Potential of the heparan sulfate mimetic OTR4120: Insights from Preclinical Models | |
| BBATProt：一种通过可解释深度学习增强特征提取的生物功能预测框架 | Wang, Y. | N/A | BBATProt: A Framework Predicting Biological Function with Enhanced Feature Extraction via Explainable Deep Learning | |
| BioStructNet：基于结构的网络与迁移学习相结合用于预测生物催化剂功能 | Wang, X. | N/A | BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions | |
| 一种用于预测和设计可成药蛋白质的集成方法。 | Jain, S. | N/A | An ensemble method for predicting and designing of druggable proteins. | |
| 在spastin中，一个与疾病相关的主要点突变显著改变了其动力学和变构效应。 | Kahawatte, S. | N/A | A major disease-related point mutation in spastin alters dramatically the dynamics and allostery of the motor | |
| 磷酸化在两种与膜相关的凝聚态之间切换SARS-CoV-2核衣壳蛋白的状态 | Favetta, B. | N/A | Phosphorylation Toggles the SARS-CoV-2 Nucleocapsid Protein Between Two Membrane-Associated Condensate States | |
| 芳香族氨基酸相互作用强度的交叉：酪氨酸与苯丙氨酸在生物分子凝聚物中的比较 | De Sancho, D. | N/A | Crossover in Aromatic Amino Acid Interaction Strength: Tyrosine vs. Phenylalanine in Biomolecular Condensates | |
| GBM中GABARAPs的差异表达以p53依赖的方式赋予替莫唑胺敏感性 | Megha, | N/A | Differential expression of GABARAPs in GBM renders temozolomide sensitivity in a p53-dependent manner | |
| SSTR2靶向的肝细胞癌治疗诊断学 | Momeny, M. | N/A | SSTR2-targeted theranostics in hepatocellular carcinoma | |
| 脱氧神经鞘脂在结肠癌细胞中激活cGAS-STING，并增强肿瘤免疫 | Saha, S. | N/A | Deoxysphingolipids activate cGAS-STING in colon cancer cells and enhance tumor immunity | |
| 从全基因组层面探究桃金娘HSF基因家族及其在热适应中的功能特征 | Li, H.-G. | N/A | A genome-wide-level insight into HSF gene family of Rhodomyrtus tomentosa and the functional characterization of RtHSFA2s genes in thermal adaption | |
| 基于代理的拟南芥合子中皮质微管带运动的模拟 | Nonoyama, T. | N/A | Agent-Based Simulation of Cortical Microtubule Band Movement in the Arabidopsis Zygote | |
| 多束神经复合动作电位的模拟分析 | Tharayil, J. J. | N/A | Simulation Insights on the Compound Action Potential in Multifascicular Nerves | |
| 非侵入性脑刺激对神经纤维瘤1型患者工作记忆任务期间有效连通性的影响 | Litwinczuk, M. C. | N/A | Effects of non-invasive brain stimulation on effective connectivity during working memory task in Neurofibromatosis Type 1 patients | |
| B细胞表达的酶PexRAP，作为醚脂生物合成中的中间体，促进了抗体反应和生发中心的大小。 | Cho, S. H. | N/A | B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size | |
| 纳米材料会引发人体免疫细胞的功能反应。 | Mittelheisser, V. | N/A | Nanomaterials trigger functional responses in primary human immune cells | |
| 腺病毒26型载体疫苗在小鼠中引发的免疫反应的早期时空演变 | Blass, E. | N/A | Early spatiotemporal evolution of the immune response elicited by adenovirus serotype 26 vector vaccination in mice | |
| 绘制微生物真核生物细胞骨架多样性的图景 | Mikus, F. | N/A | Charting the landscape of cytoskeletal diversity in microbial eukaryotes | |
| 使用时间延迟积分技术的拉曼流式细胞仪 | Lindley, M. | N/A | Raman flow cytometry using time delay integration | |
| 未能再现程序性记忆干扰对年轻和老年成人清醒状态下情景记忆巩固的影响 | Kamal, L. | N/A | Failure to reproduce the effect of procedural memory interference on wakeful consolidation of episodic memory in younger and older adults | |
| 登革病毒2型八面体小病毒样颗粒 | Johnson, A. | N/A | Octahedral small virus-like particles of dengue virus type 2 | |
| 血影蛋白协调皮质肌动蛋白-肌球蛋白的组织和分化，这对功能性上皮屏障至关重要。 | Soffer, A. | N/A | Spectrin coordinates cortical actomyosin organization and differentiation essential for a functional epithelial barrier | |
| 在CRISPR/Cas介导的染色体倒位后，表观遗传状态和基因表达保持稳定。 | Khosravi, S. | N/A | Epigenetic state and gene expression remain stable after CRISPR/Cas-mediated chromosomal inversions | |
| 靶向长链非编码RNA RP11-502I4.3可延缓糖尿病视网膜病变中的血管生成趋势 | Tan, W. | N/A | Targeting long non-coding RNA RP11-502I4.3 delays the trend of angiogenesis in diabetic retinopathy | |
| PD-L1+ 中性粒细胞在非酒精性脂肪肝病中的系统性炎症反应期间介导易感性 | Barros, C. d. C. O. | N/A | PD-L1+ Neutrophils mediate Susceptibility during Systemic Inflammatory Response in Non-Alcoholic Fatty Liver Disease | |
| 反复呈现视觉威胁会驱动先天性恐惧习惯化，并受环境和生理因素的调节。 | Carroll, J. N. | N/A | Repeated presentation of visual threats drives innate fear habituation and is modulated by environmental and physiological factors | |
| mRNA中下游结构元件对核糖体亚基间旋转动力学的影响 | Shebl, B. | N/A | The influence of downstream structured elements within mRNA on the dynamics of intersubunit rotation in ribosomes | |
| 粗粒度动态模拟细胞骨架微管扭曲 | Zhu, R. | N/A | Coarse-Grained Dynamic Simulation of Cytoskeletal Microtubule Twist | |
| 茉莉酸信号和谷胱甘肽协同调控植物从强光胁迫中恢复 | Kilic, M. | N/A | Jasmonic acid signaling and glutathione coordinate plant recovery from high light stress | |
| HEADING DATE 1基因突变对水稻转录及细胞壁组成的影响 | Biancucci, M. | N/A | Impact of mutations in the HEADING DATE 1 gene on transcription and cell wall composition of rice | |
| 通过解决GPT不准确响应和基准测试上下文来创建生物医学知识库 | Darnell, S. S. | N/A | Creating a biomedical knowledge base by addressing GPT inaccurate responses and benchmarking context | |
| 大肠杆菌的磷酸丙糖异构酶（TpiA）的结构可塑性 | Calles, B. | N/A | The structural permissiveness of triosephosphate isomerase (TpiA) of Escherichia coli | |
| 大肠杆菌在接近致死酸胁迫下的集体生长动态 | Segura Munoz, R. R. | N/A | Collective dynamics of Escherichia coli growth under near-lethal acid stress | |
| 在长期定殖过程中肠球菌物种间的异质性和代谢多样性 | Karlsson, P. A. | N/A | Heterogeneity and Metabolic Diversity among Enterococcus Species during Long-term Colonization | |
| 丝裂霉素C与低剂量甲硝唑联合使用对艰难梭菌感染及其复发具有协同作用 | Gong, J.-J. | N/A | Combination of mitomycin C and low-dose metronidazole synergistically against Clostridioides difficile infection and recurrence prevention | |
| 马拉色菌（Malassezia furfur）在替代模型宿主秀丽隐杆线虫（Caenorhabditis elegans）中的致病性和肠道屏障破坏能力，部分被鼠李糖乳杆菌（Lacticaseibacillus rhamnosus）所缓解。 | Kishida, C. | N/A | Pathogenicity and intestinal barrier disruptive ability of Malassezia furfur in an alternative model host Caenorhabditis elegans is partially alleviated by Lacticaseibacillus rhamnosus | |
| 通过多聚C结合蛋白实现的铁敏感性RNA调控 | Forbes, K. | N/A | Iron-sensitive RNA regulation by poly C binding proteins | |
| 自闭症患者血液中RNA/DNA杂交谱的分析揭示了mRNA和非编码RNA区域的差异 | Kianmehr, L. | N/A | Analysis of RNA/DNA Hybrid Profiles in Blood From Autistic Patients Reveals Differences in mRNA and non-coding RNA Regions | |
| 囊性纤维化跨膜传导调节因子（CFTR）调节剂对血液蛋白质组的系统性影响 | Fentker, K. | N/A | Systemic effects of cystic fibrosis transmembrane conductance regulator (CFTR) modulators on the blood proteome | |
| 核糖体相关质量控制因子TCF25通过结合并特异性地定向受体泛素，使得Listerin介导的新生链泛素化具有K48特异性。 | Abaeva, I. S. | N/A | The ribosome-associated quality control factor TCF25 imposes K48 specificity on Listerin-mediated ubiquitination of nascent chains by binding and specifically orienting the acceptor ubiquitin | |
| 通过胆绿素还原酶敲除实现的先进深层组织成像与操控。 | Kasatkina, L. | N/A | Advanced deep-tissue imaging and manipulation enabled by biliverdin reductase knockout. | |
| 结合环境微生物选择的微生物群落进化模型 | Xiao, Y. | N/A | Models of microbiome evolution incorporating environmental microbial selection | |
| 神经元分化过程中依赖于上下文的表观基因组重编程 | Manelli, V. | N/A | Context-dependent epigenome rewiring during neuronal differentiation | |
| 栽培柑橘的超泛基因组揭示了它们在网状进化异域分化阶段的演化特征 | Droc, G. | N/A | A super-pangenome for cultivated citrus reveals evolutive features during the allopatric phase of their reticulate evolution | |
| 通过两种GTPase因子EngA和ObgE介导的单步体外核糖体重构 | Sato, A. | N/A | Single-step in vitro ribosome reconstitution mediated by two GTPase factors, EngA and ObgE | |
| 赖氨酸特异性肽酶的比较分析，以优化蛋白质组学工作流程 | van der Hoeven, L. R. | N/A | Comparative Analysis of Lysine-Specific Peptidases for Optimizing Proteomics Workflows | |
| OfWRKY33结合关键的芳樟醇合酶基因OfTPS7，促进桂花中芳樟醇的合成 | Xi, W. | N/A | OfWRKY33 binds to the key linalool synthase gene OfTPS7 to promote linalool synthesis in Osmanthus fragrans flowers | |
| DNA依赖性蛋白激酶抑制剂PI-103和Samotolisib增强CRISPR/Cas9在人T细胞中的敲入效率 | Dzafo, E. | N/A | DNA-Dependent Protein Kinase Inhibitors PI-103 and Samotolisib Augment CRISPR/Cas9 Knockin Efficiency in Human T Cells | |
| # BioRxiv 2024-10-17 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 杂合优势可以解释免疫基因的非凡多样性。 | Siljestam, M. | N/A | Heterozygote advantage can explain the extraordinary diversity of immune genes | |
| 细菌中对多种药物产生耐药性的快速进化，且不依赖于SOS系统 | Zhang, L. | N/A | Fast Evolution of SOS-Independent Multi-Drug Resistance in Bacteria | |
| 网络的自然史：在地理历史数据中建模高阶相互作用 | Rojas, A. | N/A | A natural history of networks: Modeling higher-order interactions in geohistorical data | |
| 多组学方法揭示RNA动态促进细胞对DNA低甲基化的敏感性 | Ge, A. Y. | N/A | A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation | |
| 同时可视化单细胞RNA测序研究中的细胞及其标记基因 | Bhattacharya, N. | N/A | Simultaneous visualization of cells and marker genes from scRNA-seq studies | |
| BIBSNet：一种用于MRI扫描的深度学习婴儿图像脑部分割网络 | Hendrickson, T. J. | N/A | BIBSNet: A Deep Learning Baby Image Brain Segmentation Network for MRI Scans | |
| 目标检测调节成功记忆编码的脑电图频谱相关性 | Broitman, A. W. | N/A | Target Detection Modulates EEG Spectral Correlates of Successful Memory Encoding | |
| 基于血液的纳米定量免疫复合物检测：在诊断为帕金森病的患者中，对抑制剂耐药的种子活性检测 | Christenson, P. R. | N/A | Blood-based Nano-QuIC: Inhibitor-resistant Detection of Seeding Activity in Patients Diagnosed with Parkinson Disease | |
| 逆转录转座子和卫星DNA的周转驱动了果蝇在短期进化时间尺度上的着丝粒重构 | Courret, C. | N/A | Turnover of retroelements and satellite DNA drives centromere reorganizationover short evolutionary timescales in Drosophila | |
| 桥粒突变影响肿瘤微环境以促进黑色素瘤增殖 | Baron, M. | N/A | Desmosome mutations impact the tumor microenvironment to promote melanoma proliferation | |
| LMD: 单细胞RNA-seq数据中独立于集群的多尺度标记识别 | Li, R. | N/A | LMD: Cluster-Independent Multiscale Marker Identification in Single-cell RNA-seq Data | |
| 一个用于非平衡自组装和分枝肌动蛋白网络中力形态权衡的热力学框架 | Rennert, E. | N/A | A thermodynamic framework for nonequilibrium self-assembly and force morphology tradeoffs in branched actin networks | |
| 算法代理中的结构化动态 | Ruffini, G. | N/A | Structured dynamics in the algorithmic agent | |
| 视觉皮层中细胞类型与视觉依赖性转录程序相互作用的时空分析 | Xie, F. | N/A | Spatial profiling of the interplay between cell type- and vision-dependent transcriptomic programs in the visual cortex | |
| 最小顶点模型解释了果蝇背部闭合过程中羊膜细胞如何避免液化。 | Tah, I. | N/A | Minimal vertex model explains how the amnioserosa avoids fluidization during Drosophila dorsal closure | |
| U/V性染色体系统中性分化的发育途径 | Liesner, D. | N/A | Developmental pathways underlying sexual differentiation in a U/V sex chromosome system | |
| 神经代码追踪叙事中的先前事件，并预测后续对细节的记忆。 | Collin, S. H. P. | N/A | Neural codes track prior events in a narrative and predict subsequent memory for details | |
| 基于模型的前臂肌肉在2自由度手腕任务中使用MRE估计主动和被动肌肉力的方法 | Helm, C. A. | N/A | Model-Based Estimation of Active and Passive Muscle Forces Using MRE in Forearm Muscles During 2-DOF Wrist Tasks | |
| 查尔酮和吡唑啉衍生物的合成及其作为ELF3-MED23相互作用新型抑制剂的生物学评估 | Hwang, S.-Y. | N/A | Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction | |
| 多重检测人类疾病相关突变揭示了UTR二核苷酸组成作为RNA稳定性的主要决定因素 | Su, J.-Y. | N/A | Multiplexed Assays of Human Disease-relevant Mutations Reveal UTR Dinucleotide Composition as a Major Determinant of RNA Stability | |
| 基于压缩感知的方法识别驱动习得病原体回避的模块化神经回路 | Hallacy, T. | N/A | Compressed sensing based approach identifies modular neural circuitry driving learned pathogen avoidance | |
| 在77K下测量的叶片中从PSII到PSI的激发溢出 | Terashima, I. | N/A | Excitation Spillover from PSII to PSI Measured in Leaves at 77K | |
| 依赖于小泛素样修饰物（SON）的核斑点再生能够缓解蛋白质病 | Dion, W. | N/A | SON-dependent nuclear speckle rejuvenation alleviates proteinopathies | |
| 年轻小鼠的微生物群通过调节老年小鼠的丁酸水平，对抗了与年龄相关的痛风易感性。 | Song, N. | N/A | Microbiota from young mice counteracts susceptibility to age-related gout through modulating butyric acid levels in aged mice | |
| 高加索侏儒鰕虎鱼（Knipowitschia cf. caucasica）染色体水平基因组参考，这是一种新入侵莱茵河的鰕虎鱼科外来物种 | Schoenle, A. | N/A | Chromosome level genome reference of the Caucasian dwarf goby Knipowitschia cf. caucasica, a new alien Gobiidae invadingthe River Rhine | |
| 改变沙眼衣原体的氧化还原状态会直接影响其发育周期的进展。 | Singh, V. | N/A | Altering the redox status of Chlamydia trachomatis directly impacts its developmental cycle progression | |
| 对鼠伤寒沙门氏菌基因组抗菌药物耐药性流行病学的剖析 | Kaur, S. | N/A | A dissection of the genomic antimicrobial resistance epidemiology of Salmonella Typhimurium | |
| NHR-23调控的假定蛋白酶抑制剂mlt-11基因对于秀丽隐杆线虫（C. elegans）的表皮结构和功能是必需的。 | Ragle, J. M. | N/A | The NHR-23-regulated putative protease inhibitor mlt-11 gene is necessary for C. elegans cuticle structure and function | |
| 利用Sentence-BERT从预测数据库中精炼疾病相关蛋白质水平的微RNA靶点相互作用 | Chen, B. | N/A | Refining Protein-Level MicroRNA Target Interactions in Disease from Prediction Databases Using Sentence-BERT | |
| PVD神经元在秀丽隐杆线虫中具有雄性特异性结构和交配功能。 | Iosilevskii, Y. | N/A | The PVD neuron has male-specific structure and mating function in C. elegans | |
| HIV-1感染与生发中心B细胞的耗竭以及胃肠道中IgA+浆细胞的减少有关。 | Cossarini, F. | N/A | HIV-1 infection is associated with depletion of germinal center B cells and a decrease in IgA+ plasma cells in the GI tract | |
| 环二腺苷酸推动沙眼衣原体发育周期的进展 | Lee, J. | N/A | Cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis | |
| 多物理场模拟揭示了患者来源的左心房组织力学中与纤维化相关的变化对血流动力学的影响 | Gonzalo, A. | N/A | Multi-physics simulations reveal hemodynamic impacts of patient-derived fibrosis-related changes in left atrial tissue mechanics | |
| 累积的储备阻碍了与年龄相关的噪音中言语感知中的神经补偿 | Zhang, L. | N/A | Accumulated reserves hold back age-related neural compensation in speech-in-noise perception | |
| ProtEx：一种用于蛋白质功能预测的检索增强方法 | Shaw, P. | N/A | ProtEx: A Retrieval-Augmented Approach for Protein Function Prediction | |
| 使用语言模型进行蛋白质序列域注释 | Sarkar, A. | N/A | Protein Sequence Domain Annotation using Language Models | |
| Gap-App：一种基于性别的AI胰腺导管腺癌生存预测器，作为面向患者和医生的网络应用程序开放 | Ojha, A. | N/A | Gap-App: A sex-distinct AI-based predictor for pancreatic ductal adenocarcinoma survival as a web application open to patients and physicians | |
| 使用键合图对单个肌动蛋白丝聚合进行基于能量的建模 | Gawthrop, P. | N/A | Energy-based Modelling of Single Actin Filament Polymerisation Using Bond Graphs | |
| 黑色素化与土壤矿物和微生物特性相互作用，共同决定土壤中真菌碳和氮的持久性。 | Beidler, K. V. | N/A | Melanization interacts with soil mineral and microbial properties to determine fungal carbon and nitrogen persistence in soils | |
| 分层种群遗传结构和适应性特征在尖吻鲈（Lates calcarifer）中的体现 | Campbell, M. A. | N/A | Hierarchical population genetic structure and signatures of adaptation in Lates calcarifer | |
| 翼龙尾巴羽片的新软组织数据显示了其复杂、动态的张力使用方式，并扩展了其进化起源。 | Jagielska, N. | N/A | New soft tissue data of pterosaur tail vane reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins | |
| I2Bot：一种用于昆虫导航的多模态和具身模拟的开源工具 | Sun, X. | N/A | I2Bot: an open-source tool for multi-modal and embodied simulation of insect navigation | |
| 基于石墨烯的微电极，具有增强的界面和可调的孔隙结构，用于提高神经记录效果 | Dong, M. | N/A | Graphene-based micro-electrodes with reinforced interfaces and tunable porous structures for improved neural recordings | |
| Xist RNA结合特定的常染色体基因，并依赖于重复序列B来调控这些基因的表达。 | Yao, S. | N/A | Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression | |
| 硫醚功能化纤维素用于制备氧化响应性生物材料涂层和薄膜 | DuBois, E. M. | N/A | Thioether-functionalized cellulose for the fabrication of oxidation-responsive biomaterial coatings and films | |
| 爱荷华脑行为建模工具包：一个用于成像-行为和损伤-缺陷关系推断与预测建模的开源MATLAB工具 | Griffis, J. C. | N/A | Iowa Brain-Behavior Modeling Toolkit: An Open-Source MATLAB Tool for Inferential and Predictive Modeling of Imaging-Behavior and Lesion-Deficit Relationships | |
| 一类新的受体：脂质通过其膜锚定物调节哺乳动物Gsα刺激的腺苷酸环化酶活性 | Landau, M. | N/A | A new class of receptors: Lipids regulate mammalian Gsα-stimulated adenylyl cyclase activities via their membrane anchors | |
| 百日咳博德特氏菌疫苗反应中的Th1极化通过正反馈回路得以维持。 | Willemsen, L. | N/A | Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop | |
| 不同表型水稻干旱和盐胁迫公共RNA测序数据的Meta分析 | Shintani, M. | N/A | Meta-analysis of public RNA-sequencing Data of Drought and Salt Stresses in Different Phenotypes of Oryza sativa | |
| 使用扩散模型生成P型ATP酶的多状态构象 | Xu, J. | N/A | Generating Multi-state Conformations of P-type ATPases with a Diffusion Model | |
| 生物分子凝聚体在相分离的质量守恒反应扩散系统实验与理论之间架起了桥梁。 | Li, C. | N/A | Biomolecular condensates bridge experiment and theory of mass-conserving reaction-diffusion systems in phase separation | |
| 领地性和资源可用性调节同种个体相遇对哺乳动物捕食者觅食行为的影响 | Clermont, J. | N/A | Territoriality and resource availability modulate the effect of conspecific encounters on the foraging behaviours of a mammalian predator | |
| VP35中隐秘口袋的打开和关闭使其在两种不同的RNA结合模式之间切换。 | Mallimadugula, U. L. | N/A | Opening and closing of a cryptic pocket in VP35 toggles it between two different RNA-binding modes | |
| 开发日本柳杉D. Don中雄性不育4 (MS4)基因的简易DNA提取和PCR-RFLP方法：迈向环境友好型协议 | Ueno, S. | N/A | Developing simple DNA extraction and PCR-RFLP for MALE STERILITY 4 (MS4) gene in Cryptomeria japonica D. Don: Toward an environmentally friendly protocol | |
| RNA在α-突触核蛋白相分离的纳米尺度组织中的作用 | Zappone, S. | N/A | The role of RNA in the nanoscale organization of alpha-synuclein phase separation | |
| 多发性硬化症中克隆扩增的CD8+ T细胞的抗原特异性 | Mittl, K. | N/A | Antigen-specificity of clonally-enriched CD8+ T cells in multiple sclerosis | |
| 通过双向循环门控建模大脑中的注意力和绑定机制 | Salehinajafabadi, S. | N/A | Modeling Attention and Binding in the Brain through Bidirectional Recurrent Gating | |
| 致癌驱动突变N642H在STAT5B SH2结构域中的结构影响 | Haas-Neill, L. | N/A | The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain | |
| 基于角色共享的协同群体行为分析：从实验任务到3对3篮球比赛的实际应用作为试点研究 | Ichikawa, J. | N/A | Analysis of coordinated group behavior based on role-sharing: Practical application from an experimental task to a 3-on-3 basketball game as a pilot study | |
| 在小鼠齿状回中，5-HT7受体的激活并不影响穿通路径突触处的θ波爆发诱导的可塑性。 | Siwiec, M. | N/A | Activation of 5-HT7 receptors in the mouse dentate gyrus does not affect theta-burst-induced plasticity at the perforant path synapse | |
| 在小鼠齿状回中，5-HT7受体的激活并不影响穿通路径突触处的theta波簇诱导的可塑性。 | Siwiec, M. | N/A | Activation of 5-HT7 receptors in the mouse dentate gyrus does not affect theta-burst-induced plasticity at the perforant path synapse | |
| 模仿机制：肉类与肉类替代品的比较 | St. Pierre, S. R. | N/A | Mimicking mechanics: A comparison of meat and meat analogs | |
| 外膜变化使细菌能够逃避捕食 | Mridha, S. | N/A | Outer membrane changes enable evolutionary escape from bacterial predation | |
| stFormer：一种用于空间转录组学的基石模型 | Cao, S. | N/A | stFormer: a foundation model for spatial transcriptomics | |
| 细菌的运动模式能够顺利适应空间限制和紊乱的变化 | Zhang, H. | N/A | Bacterial motility patterns adapt smoothly in response to spatial confinement and disorder | |
| 神经运动生成的空间和网络原理 | Komi, S. | N/A | Spatial and network principles behind neural generation of locomotion | |
| James-Stein估计器提高了人体运动学和代谢数据中的准确性和样本效率。 | Alwan, A. | N/A | James-Stein estimator improves accuracy and sample efficiency in human kinematic and metabolic data | |
| 一种非典型的E3连接酶在营养应激期间保护核糖体 | Douglas, T. | N/A | An atypical E3 ligase safeguards the ribosome during nutrient stress | |
| 计算微生物组药理学分析阐明阴道微生物及其代谢物的抗癌潜力 | Lawore, D. C. | N/A | Computational Microbiome Pharmacology Analysis Elucidates the Anti-Cancer Potential of Vaginal Microbes and Metabolites | |
| 腹侧纹状体与凸显网络具有特别密切的关联，该网络包括背外侧前额叶皮层中的区域。 | Kosakowski, H. L. | N/A | Ventral Striatum is Preferentially Correlated with the Salience Network Including Regions in Dorsolateral Prefrontal Cortex | |
| 从生物物理模型和保存的标本中可靠地重建蟋蟀鸣声 | Weiner, R. J. | N/A | Reliable reconstruction of cricket song from biophysical models and preserved specimens | |
| 多成分营养补充剂与衰老干预在老年小鼠中具有可比的抗衰老功效 | Brookes, C. | N/A | Comparable anti-ageing efficacies of a multi-ingredient nutraceutical and a senolytic intervention in old mice | |
| 两种亚麻品种的比较分析表明，木脂素介导的盐胁迫适应性 | Debnath, A. J. | N/A | A comparative analysis between two flax varieties indicates lignan-mediated salt stress adaptiveness | |
| 用于酶学表征菱形蛋白酶RHBDL4的体外平台 | Bhaduri, S. E. | N/A | An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4 | |
| 半监督组学因子分析（SOFA）在多组学数据中将已知的变异源与潜在因子解耦。 | Capraz, T. | N/A | Semi-supervised Omics Factor Analysis (SOFA) disentangles known sources of variation from latent factors in multi-omics data | |
| 用于预测血脑屏障渗透性的注意力图神经网络模型 | Collins, J. W. | N/A | Attentive graph neural network models for the prediction of blood-brain barrier permeability | |
| 用于预测血脑屏障渗透性的注意力图神经网络模型 | Collins, J. W. | N/A | Attentive graph neural network models for the prediction of blood-brain barrier permeability | |
| Asgard古菌对真核生物起源的显著贡献 | Tobiasson, V. | N/A | Dominant contribution of Asgard archaea to eukaryogenesis | |
| 通过整合多层次事件时间概率分布进行时间预测 | Huang, Y. T. | N/A | Temporal Prediction through Integration of Probability Distributions of Event Timings at Multiple Levels | |
| 多巴胺在执行动作序列期间奖励预期和可预测性中的作用 | Magnard, R. | N/A | Role of dopamine in reward expectation and predictability during execution of action sequences | |
| 理解神经元多样性：输入动力学和选择性的作用 | Joshi, N. | N/A | Understanding Neuronal Diversity: Role of Input Dynamics and Selectivity | |
| 在高级皮质网络中，阿尔法和贝塔节律中的时间延迟表征随着关系整合需求的增加而追踪。 | Robinson, C. N. | N/A | Temporally delayed representations in alpha and beta rhythms in higher-order cortical networks track increasing relational integration demands | |
| 海马体中刺激意义的表征 | Biane, J. S. | N/A | Representations of stimulus meaning in the hippocampus | |
| 活性氧物种的增加是新生儿小脑修复的基础 | Pakula, A. | N/A | An increase in reactive oxygen species underlies neonatal cerebellum repair | |
| 准确而灵活的有效群体数量历史估计 | Huang, Z. | N/A | Accurate and flexible estimation of effective population size history | |
| SPLENDID 在生物银行规模的数据中整合了连续的遗传祖先信息，以提高不同人群的多基因风险预测能力。 | Chen, T. | N/A | SPLENDID incorporates continuous genetic ancestry in biobank-scale data to improve polygenic risk prediction across diverse populations | |
| KLHDC7B是一种与人类年龄相关性听力损失相关的新基因，对于维持小鼠的听力是必需的。 | Kaufman, A. M. | N/A | KLHDC7B, a novel gene associated with age-related hearing loss in humans, is required for the maintenance of hearing in mice. | |
| 通过靶向3D基因组，利用蒽环类药物实现化疗效果 | Tan, M. | N/A | Targeting the 3D genome by anthracyclines for chemotherapeutic effects | |
| 小脑在认知老化中的保护作用 | d'Oleire Uquillas, F. | N/A | A protective role for the cerebellum in cognitive aging | |
| 前额叶协调：一种用于啮齿动物运动抑制的皮层网络 | Jaeckel, Z. | N/A | Prefrontal orchestration: a cortical network for rodent motor inhibition | |
| 神经元的限制性N-糖基化在分化过程中被编程 | Kiwimagi, K. | N/A | The restricted N-glycome of neurons is programmed during differentiation | |
| 综合应激反应通过维持线粒体输入效率来抑制依赖于PINK1的线粒体自噬 | Yang, M. | N/A | The Integrated Stress Response Suppresses PINK1-dependent Mitophagy by Preserving Mitochondrial Import Efficiency | |
| 利用稳定同位素示踪法建模复合脂质稳态 | Wessendorf-Rodriguez, K. | N/A | Modeling Compound Lipid Homeostasis Using Stable Isotope Tracing | |
| GRASP55调控溶酶体酶β-氨基己糖苷酶A的分选与成熟 | Akaaboune, S. R. | N/A | GRASP55 Regulates Sorting and Maturation of the Lysosomal Enzyme β-Hexosaminidase A | |
| 袖内运输同时利用了微管和肌动蛋白轨道。 | Judernatz, J. | N/A | Intra-manchette transport employs both microtubule and actin tracks | |
| BAK驱动的凋亡孔形成的脂质特征 | Uren, R. T. | N/A | A lipid signature of BAK-driven apoptotic pore formation | |
| 全面鉴定质膜修复蛋白揭示了细胞对质膜损伤的时空响应 | Yamazaki, Y. | N/A | Comprehensive identification of plasma membrane repair proteins revealed spatiotemporal cellular responses to plasma membrane damage | |
| β-肾上腺素能阻滞剂通过胰腺β细胞中的PKA/RYR2/TRPM5途径增加cAMP并刺激胰岛素分泌（体外实验） | Murao, N. | N/A | β-adrenergic blockers increase cAMP and stimulate insulin secretion through a PKA/RYR2/TRPM5 pathway in pancreatic β-cells in vitro | |
| I类PAK在调节肌动蛋白细胞骨架兴奋性中的作用。 | Tyler, J. J. | N/A | A role for class I PAKs in the regulation of the excitability of the actin cytoskeleton. | |
| 新型抗体可检测原生生物病原体、细胞黏菌和植物中的核内质O-岩藻糖 | Tiwari, M. | N/A | Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants | |
| 自闭症中的白质微结构改变通过束分析定位 | Kim, G. S. | N/A | White Matter Microstructural Alterations in Autism Localized with Bundle Analytics | |
| 对一种脆海星中荧光素酶的功能表征表明，平行进化受到卤代烷脱卤酶基因组可用性的影响。 | Lau, E. S. | N/A | Functional characterization of luciferase in a brittle star indicates parallel evolution influenced by genomic availability of haloalkane dehalogenase | |
| 光照在弱电鱼的活动感知和控制中起到中介作用，促使两者发生转变。 | Yeh, H. | N/A | Illumination mediates a switch in both active sensing and control in weakly electric fish | |
| 在“通过网络推断和计算机模拟基因扰动剖析细胞身份”中发现的重大问题 | Nourisa, J. | N/A | Critical issues found in "Dissecting cell identity via network inference and in silico gene perturbation" | |
| 淡水螺类Physa acuta中，同代与跨代捕食者诱导可塑性的转录组基础 | Dejeux, L. | N/A | Transcriptomic bases of within- and trans-generational predator-induced plasticity in the freshwater snail Physa acuta | |
| 集成机器学习在代谢组数据中的应用：识别与巨噬细胞极化相关的代谢物 | Gannavaram, A. | N/A | Application of Ensemble Machine Learning to Metabolomic Data Identifies Metabolites Associated with Macrophage Polarization | |
| 囊杆菌素脱靶分析揭示了其在真核生物中具有良好的安全性、超氧化物还原能力以及SCARB1抑制作用 | Risch, T. | N/A | Cystobactamid off-target profiling reveals favorable safety, superoxide reduction, and SCARB1 inhibition in eukaryotes | |
| 三种细胞色素P450酶在鼠尾草属植物中催化形成呋喃克罗烷前体。 | Lin, R. | N/A | Three cytochrome P450 enzymes catalyse the formation of furanoclerodane precursors in Salvia spp. | |
| 对来自芬兰的首个巨型病毒Jyväskylä病毒的基因组和结构深入研究 | de Freitas Almeida, G. M. | N/A | Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland | |
| 高糖食物会加剧抗生素引起的微生物群损伤。 | Dai, A. | N/A | Sugar-rich foods exacerbate antibiotic-induced microbiome injury | |
| 丝裂霉素C在金黄色葡萄球菌适应性实验室进化后仍保持疗效 | Petersen, M. E. | N/A | Mitomycin C Retains Efficacy after Adaptive Laboratory Evolution of Staphylococcus aureus | |
| 小分子激活TFEB通过促进溶酶体胞吐作用和生物发生缓解尼曼-皮克病C型 | Du, K. | N/A | Small-molecule Activation of TFEB Alleviates Niemann-Pick Disease Type C via Promoting Lysosomal Exocytosis and Biogenesis | |
| 有丝分裂纺锤体的定向和动态变化通过NuMA定位在各向异性组织拉伸的作用下得到了精细调节。 | Tarannum, N. | N/A | Mitotic spindle orientation and dynamics are fine-tuned by anisotropic tissue stretch via NuMA localisation | |
| TRIM蛋白家族中RING E3假性联酶的鉴定 | Dudley-Fraser, J. | N/A | Identification of RING E3 pseudoligases in the TRIM protein family | |
| Nrf2 调控表观遗传学调节，并在砷诱导的转化过程中作为 KLF4 表达和活性的主调控因子。 | Wang, Z. | N/A | Nrf2 orchestrates epigenetic regulations and serves as the master regulator of KLF4 expression and activity during arsenic-induced transformation | |
| 复制白细胞介素-15超级激动剂的逆转录病毒传递，可增强抗肿瘤免疫并提高低免疫原性胶质母细胞瘤模型中的长期生存率 | Haddad, A. F. | N/A | Replicating retroviral delivery of an IL-15 superagonist improves antitumor immunity and long-term survival in poorly immunogenic glioblastoma models | |
| 复制白细胞介素-15超级激动剂的逆转录病毒传递方式可增强抗肿瘤免疫并提高低免疫原性胶质母细胞瘤模型的长期生存率 | Haddad, A. F. | N/A | Replicating retroviral delivery of an IL-15 superagonist improves antitumor immunity and long-term survival in poorly immunogenic glioblastoma models | |
| DDX41通过溶解G-四链体来维持红细胞基因组的完整性，并防止cGAS介导的细胞死亡。 | Bi, H. | N/A | DDX41 dissolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death | |
| 芸薹属植物（Brassica campestris L. ssp. chinensis）中生长调节因子BRAGRF5的分子特征及启动子元件分析 | Wang, X.-Y. | N/A | MOLECULAR CHARACTERIZATION AND PROMOTER ELEMENT ANALYSIS OF GROWTH REGULATOR BRAGRF5 IN BRASSICA CAMPESTRIS L. SSP. CHINENSIS | |
| 脱脂辣木籽的生化和植物化学功效在对抗营养不良中的作用 | Jegede, R. E. | N/A | Biochemical and Phytochemical Efficacy of Defatted Moringa oleifera Seeds in combating Malnutrition | |
| 褐藻门三角褐指藻Seipin同源蛋白的功能研究突显了硅藻脂滴生物发生的独特特征。 | Le Moigne, D. | N/A | Functional study of Phaeodactylum tricornutum Seipin homolog highlights unique features of lipid droplets biogenesis in diatoms. | |
| OpenASO：RNA救援——通过社区科学设计剪接调节反义寡核苷酸 | Tse, V. | N/A | OpenASO: RNA Rescue--designing splice-modulating antisense oligonucleotides through community science | |
| 耗竭的贩运调节因子CASK促进间插盘组织和心室功能 | Blandin, C. E. | N/A | Depleting trafficking regulator CASK promotes intercalated disc organization and ventricular function | |
| AAA-ATP酶Cdc48p在过氧化物酶体质量控制中的作用 | Yusuf, I. F. | N/A | Role of AAA-ATPase Cdc48p in Peroxisomal Quality Control | |
| 使用结构化溯祖模型进行病原体系统地理学贝叶斯推断 | Roberts, I. | N/A | Bayesian Inference of Pathogen Phylogeography using the Structured Coalescent Model | |
| 微生物组如何从血红素中释放铁 | Nath, A. K. | N/A | How the microbiome liberates iron from heme | |
| 一项全面的工程策略提升了针对HIV的近泛中和抗体的效力和生产可行性 | Sajadi, M. | N/A | A Comprehensive Engineering Strategy Improves Potency and Manufacturability of a Near Pan-neutralizing Antibody Against HIV | |
| 通过综合19F-NMR技术比较了人源GPCR在脂质囊泡和水溶液中的构象平衡 | Ray, A. | N/A | The conformational equilibria of a human GPCR compared between lipid vesicles and aqueous solutions by integrative 19F-NMR | |
| 将阿托摩尔级检测带至即时护理点：基于纳米图案DNA折纸的纳米天线技术 | Yaadav, R. | N/A | Bringing Attomolar Detection to the Point-of-Care with Nanopatterned DNA Origami Nanoantennas | |
| 高表达的细胞壁基因有助于花萼大小的稳定性 | Hartasanchez, D. A. | N/A | Highly expressed cell wall genes contribute to robustness of sepal size | |
| 代谢相互作用驱动交叉喂养微生物群落中的种群周期 | Ross, T. | N/A | Metabolic interplay drives population cycles in a cross-feeding microbial community | |
| 热带海鸟（Sula）在加利福尼亚洋流生态系统中数量增加，与海洋变暖条件相关 | Russell, T. M. | N/A | Increase of tropical seabirds (Sula) in the California Current Ecosystem with warmer ocean conditions | |
| 台湾精准医疗计划：大规模研究队列 | Yang, H.-C. | N/A | The Taiwan Precision Medicine Initiative: A Cohort for Large-Scale Studies | |
| 人类脑组织中RNA质量指标的分析 | Tian, J. | N/A | An analysis of RNA quality metrics in human brain tissue | |
| 靶向质谱法揭示了啮齿动物多囊卵巢综合征模型中激素和生物活性脂质血浆谱的改变 | Scott, H. C. | N/A | Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry | |
| 在肌肉糖原含量降低的情况下进行耐力运动会影响底物利用，并减弱人类I型和II型肌纤维中的急性mTORC1信号和自噬信号。 | Horwath, O. | N/A | Endurance exercise with reduced muscle glycogen content influences substrate utilization and attenuates acute mTORC1- and autophagic signaling in human type I and type II muscle fibers | |
| 早期生命病毒组研究中的负样本：特征与去污染 | Kuzub, N. | N/A | Negativeome in Early-Life Virome Studies: Characterization and Decontamination | |
| 微空间尺度下土壤微节肢动物群落构建——一项微宇宙操控研究 | Dirilgen, T. | N/A | Soil microarthropod community assembly at the micro spatial scale - A microcosm manipulation study | |
| Dexrazoxane作为冈比亚按蚊中可行的微孢子虫控制剂 | Zeferino, T. G. | N/A | Dexrazoxane as a viable microsporidia control agent in Anopheles gambiae | |
| 未来气候下褐藻（Ascophyllum nodosum）的热应激：不同种群的敏感性差异。 | Pereira, L. F. | N/A | Heat Stress on the brown Seaweed Ascophyllum nodosum: differential population sensitivity to future climate. | |
| PARMIK：基于廉价K-mer的部分读取匹配 | Baradaran, M. | N/A | PARMIK: PArtial Read Matching with Inexpensive K-mers | |
| 转录过程中RNA折叠中间体的顺序结构探测 | Szyjka, C. E. | N/A | Sequential structure probing of cotranscriptional RNA folding intermediates | |
| 一种高保真的人类DNA聚合酶全酶具有广泛的损伤旁路活性。 | Dannenberg, R. L. | N/A | A human high-fidelity DNA polymerase holoenzyme has a wide range of lesion bypass activities | |
| 模拟悬浮细胞的三维折射率分布 | Borrelli, F. | N/A | Simulating 3D refractive index distributions of suspended cells | |
| 阴离子脂质对阴离子交换蛋白1（AE1）构象转变能量景观的影响 | Chen, T. | N/A | Impact of anionic lipids on the energy landscape of conformational transition in anion exchanger 1 (AE1) | |
| 扭转是DNA复制停滞和重新激活的动态调节器 | Jia, X. | N/A | Torsion is a Dynamic Regulator of DNA Replication Stalling and Reactivation | |
| 表达GRK2氨基末端肽转基因小鼠中的女性特异性限制性心肌病与代谢紊乱 | Bledzka, K. M. | N/A | Female Specific Restrictive Cardiomyopathy and Metabolic Dysregulation in transgenic mice expressing a Peptide of the Amino-Terminus of GRK2 | |
| DD基因组的整合重塑了异源六倍体小麦的基因转录、染色质结构和代谢组，从而增强了其适应性。 | Liu, Y. | N/A | Integration of the DD-genome reshapes gene transcription, chromatin architecture and metabolome of allohexaploid wheat leading to enhanced adaptability | |
| Aβ靶向的synNotch受体用于阿尔茨海默病：扩展应用至胞外蛋白聚集体 | Bergo, N. J. | N/A | Aβ-targeting synNotch Receptor for Alzheimer's Disease: Expanding Applications to Extracellular Protein Aggregates | |
| STRAIGHT-IN 双载体系统：一种用于将DNA有效载荷和基因电路双拷贝、单拷贝整合到人类诱导多能干细胞中的平台 | Blanch Asensio, A. | N/A | STRAIGHT-IN Dual: a platform for dual, single-copyintegrations of DNA payloads and gene circuits into human induced pluripotent stem cells | |
| 鸡盲肠中微生物群落的代谢建模揭示了竞争与合作并存的格局 | Utkina, I. | N/A | Metabolic modeling of microbial communities in the chicken ceca reveals a landscape of competition and co-operation | |
| 转录组增强的水稻籽粒代谢模型识别出组氨酸水平作为籽粒粉质度的标志 | Chowdhury, N. B. | N/A | Transcriptome Enhanced Rice Grain Metabolic Model Identifies Histidine Level as a Marker for Grain Chalkiness | |
| 马凡综合征雌性小鼠的皮质神经元中凋亡增加。 | Esfandiarei, M. | N/A | Apoptosis is increased in cortical neurons of female Marfan Syndrome mice | |
| 解开焦虑、自闭和精神病特质对感知推断的影响 | Bevalot, C. | N/A | Disentangling the effects of Anxious, Autistic and Psychotic Traits on Perceptual Inference | |
| 使用超高分辨率全脑扩散MRI直接分割皮层细胞构筑域 | Pas, K. E. | N/A | Direct segmentation of cortical cytoarchitectonic domains using ultra-high-resolution whole-brain diffusion MRI | |
| 背景光流会调节多个下行中间神经元对蝗虫中物体运动的反应 | Zhang, S. | N/A | Background optic flow modulates responses of multiple descending interneurons to object motion in locusts | |
| 敲除与LRRK2对抗的RAB磷酸酶PPM1H会破坏轴突自噬并加剧α-突触核蛋白的聚集 | Fricke, M. | N/A | Knockout of the LRRK2-counteracting RAB phosphatase PPM1H disrupts axonal autophagy and exacerbates alpha-synuclein aggregation | |
| m6A介导的表观转录组失调是脆性X综合征中突触功能障碍的基础 | Guo, Z. | N/A | m6A-mediated epi-transcriptomic dysregulation underlies synaptic dysfunction in fragile X syndrome | |
| 血管周围和实质液体的特征与整个生命周期中的年龄和认知表现有关。 | Lynch, K. M. | N/A | Perivascular and parenchymal fluid characteristics are related to age and cognitive performance across the lifespan | |
| Pep2Vec：一种用于肽-MHC呈递预测和配体组数据集中污染物鉴定的可解释模型 | Thrift, W. J. | N/A | Pep2Vec: An Interpretable Model for Peptide-MHC Presentation Prediction and Contaminant Identification in Ligandome Datasets | |
| 从重组蛋白自发形成不同形式的α-突触核蛋白纤维 | Egorov, V. V. | N/A | Spontaneous formation of different forms of alpha-synuclein fibrils from a recombinant protein | |
| 微生物iCLIP2：通过促进蛋白质和RNA的稳定性增强RNA-蛋白质相互作用的映射 | Stoffel, N. K. | N/A | Microbial iCLIP2: Enhanced mapping of RNA-Protein interaction by promoting protein and RNA stability | |
| BMP-9和BMP-10中链间二硫键形成的分子基础 | Schwartze, T. A. | N/A | Molecular basis of interchain disulfide-bond formation in BMP-9 and BMP-10 | |
| 拯救迪纳拉山猫：多学科监测与利益相关者参与助力大型食肉动物在人类主导景观中的恢复 | Krofel, M. | N/A | Saving the Dinaric lynx: multidisciplinary monitoring and stakeholder engagement support large carnivore restoration in human-dominated landscape | |
| 加利福尼亚岩质潮间带的一个包含寄生生物的食物网 | Zilz, Z. L. | N/A | A parasite-inclusive food web for the California rocky intertidal zone | |
| 评估植物-微生物群落在应对环境胁迫下的相互作用，以增强盐沼恢复效果 | Davis, K. A. | N/A | Evaluating Plant-Microbe Associations in Response to Environmental Stressors to Enhance Salt Marsh Restoration | |
| 保护区是否在追踪对陆地生物多样性的威胁？ | Pulido Chadid, K. | N/A | Are protected areas tracking threats to terrestrial biodiversity? | |
| 基于谱系的丙型肝炎病毒宿主内动态演化分析 | Zhao, L. | N/A | Lineage-aware evolutionary analysis of hepatitis C virus within-host dynamics | |
| ISWI染色质重塑因子SMARCA5对哺乳动物减数分裂基因表达和雄性生育力至关重要 | Kataruka, S. | N/A | ISWI chromatin remodeler SMARCA5 is essential for meiotic gene expression and male fertility in mammals | |
| 基准贝叶斯共定位方法在验证基于孟德尔随机化的循环蛋白质对心血管代谢疾病目标发现中的应用 | Zhang, W. | N/A | Benchmarking Bayesian colocalization methods in validating Mendelian randomization-based target discoveries from circulating proteins for cardiometabolic diseases | |
| 人类海马体衰老过程中的表观遗传与三维基因组重编程 | Zemke, N. | N/A | Epigenetic and 3D genome reprogramming during the aging of human hippocampus | |
| 从南设得兰群岛（南极洲）采集的巨藻鸥（Larus dominicanus）粪便中检测到德尔塔冠状病毒及其他鸟类相关病毒，并进行了全基因组测序。 | Gomes, F. | N/A | Detection and full genome sequencing of a Deltacoronavirus and other bird associated viruses from feces of the kelp gull (Larus dominicanus) sampled at the South Shetland Islands Antarctica. | |
| 疾病结肠组织中的eQTL鉴定出与IBD相关的新靶基因 | Nishiyama, N. C. | N/A | eQTL in diseased colon tissue identifies novel target genes associated with IBD | |
| 从动物行为和福利的角度来看，监狱犬类训练计划的效果如何？ | Baria-Unwalla, P. | N/A | What's in it for the dogs? Assessing the outcomes of a prison-based dog training program from an animal behavior and welfare perspective | |
| 端到端多模态深度学习用于实时解码来自同一细胞的数月长神经活动 | He, Y. | N/A | End-to-end multimodal deep learning for real-time decoding of months-long neural activity from the same cells | |
| 合成与表征氯喹修饰的白蛋白结合siRNA-脂质偶联物，以提高癌细胞内的递送效率和基因沉默效果 | Lo, J. H. | N/A | Synthesis and characterization of chloroquine-modified albumin-binding siRNA-lipid conjugates for improved intracellular delivery and gene silencing in cancer cells | |
| 特定领域人工智能对小鼠胚胎干细胞中IMPDH2杆/环结构的分割 | Ball, S. T. M. | N/A | Domain Specific AI Segmentation of IMPDH2 Rod/Ring Structures in Mouse Embryonic Stem Cells | |
| 肺炎克雷伯菌株在白蚁、黑猩猩和人类之间的循环 | Houmenou, C. T. | N/A | Circulation of Klebsiella pneumoniae strains between the termites, chimpanzees and humans | |
| 微生物组数据分析的半合成模拟 | Sankaran, K. | N/A | Semisynthetic Simulation for Microbiome Data Analysis | |
| 基于上下文的细菌基因组蛋白质功能预测 | Toibazar, D. | N/A | Context-based protein function prediction in bacterial genomes | |
| 扩展和改进核苷酸重编码RNA-seq实验分析的EZbakR套件 | Vock, I. | N/A | Expanding and improving analyses of nucleotide recoding RNA-seq experiments with the EZbakR suite | |
| EGFR与酪氨酸激酶抑制剂相互作用的氢氘交换质谱（HDX-MS）研究 | Ashtekar, K. D. | N/A | EGFR and tyrosine kinase inhibitor interactions probed by hydrogen-deuterium exchange and mass spectrometry (HDX-MS) | |
| CDK4/6与PI3K抑制剂的新型组合在尤文肉瘤中展现出高度协同作用及转化潜力。 | De Los Santos, M. A. I. C. | N/A | A novel combination of CDK4/6 and PI3K inhibitors exhibits highly synergistic activity and translational potential in Ewing sarcoma. | |
| F(ab)'2片段相对于IgG在RIT和PRIT中的优势 | Tabaja, Z. E. | N/A | Advantage of the F(ab)'2 fragment over IgG for RIT and PRIT | |
| 整合的人类骨骼肌单细胞功能蛋白质组学分析揭示了nemaline肌病中细胞特异性的转变 | Seaborne, R. A. E. | N/A | Integrated single cell functional-proteomic profiling of human skeletal muscle reveals a shift in cellular specificity in nemaline myopathy | |
| 光呼吸的替代方案：系统级分析揭示了提高植物生产力的机制 | Smith, E. N. | N/A | Alternatives to photorespiration: A systems-level analysis reveals mechanisms of enhanced plant productivity | |
| 利用昼夜节律钟调控的顺式调控突变，构成了自然选择下阿拉伯芥哈勒里极端性状的基础。 | Castanedo, L. | N/A | Cis-regulatory mutations co-opting circadian clock regulation underlie naturally selected extreme trait in Arabidopsis halleri | |
| 溢出率并不能预测宿主跳跃的风险。 | Simony, B. J. | N/A | Spillover rate is not predictive of host jump risk | |
| 一份详尽的蛋白质组和磷酸蛋白质组在不同小鼠组织和脑区中的周转图谱 | Li, W. | N/A | An Extensive Atlas of Proteome and Phosphoproteome Turnover Across Mouse Tissues and Brain Regions | |
| 微生物产生的胆汁酸与纤维肌痛患者中高水平IgG自身抗体和较差的心理健康状况相关。 | Jakobsson, J. E. | N/A | Microbially produced bile acids are associated with high levels of IgG autoantibodies and worse mental wellbeingin fibromyalgia subjects | |
| 空间频率通道介导了人类空间知觉的视觉度量 | Zhang, S. | N/A | Spatial frequency channels mediate a visual metric for human spatial perception | |
| 时间泛化有界积累模型优于现有模型，并能捕捉模态差异和学习效应。 | Ofir, N. | N/A | A bounded accumulation model of temporal generalization outperforms existing models and captures modality differences and learning effects | |
| 正念训练影响与青少年压力反应相关的大脑网络动态。 | Gaviria, J. | N/A | Mindfulness training impacts brain network dynamics linked to stress response in young adolescents. | |
| Nlrp3的遗传消除可防止散发性和R345W Efemp1诱导的基底层沉积物形成 | Ortega, A. J. | N/A | Genetic removal of Nlrp3 protects against sporadic and R345W Efemp1-induced basal laminar deposit formation | |
| SARS-CoV-2 XEC变种的病毒学特征 | Kaku, Y. | N/A | Virological characteristics of the SARS-CoV-2 XEC variant | |
| SFSWAP是OGT内含子滞留和全局前体mRNA剪接的负调控因子 | Govindan, A. | N/A | SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing | |
| 在大陆尺度的样地网络中，探测生态系统对气候变化和干扰响应的趋势：一项功效分析 | Guerin, G. R. | N/A | Detecting ecosystem trends in response to climate and disturbance across continental plot networks: a power analysis | |
| 细菌-噬菌体（共）进化在合成群落中受到多对细菌-噬菌体相互作用的限制 | Castledine, M. | N/A | Bacteria-phage (co)evolution is constrained in a synthetic community across multiple bacteria-phage pairs | |
| 用于评估体外细胞表型与整体生物表型相关性的遗传工具变量框架 | Howe, L. J. | N/A | Genetic instrumental variable framework for assessing relevance of in-vitro cellular phenotypes to organism-level phenotypes | |
| 对9,482株结核分枝杆菌的拷贝数变异分析揭示了谱系特异性分子决定因素。 | Bhalla, N. | N/A | Copy number variation analysis of 9,482 Mycobacterium tuberculosis isolates identifies lineage-specific molecular determinants. | |
| 弯果蓝蓟（Pectocarya recurvata）染色体水平参考基因组，该物种是紫草科中基因组最小的物种之一。 | Northing, P. C. | N/A | Chromosome-scale reference genome of Pectocarya recurvata, a species with one of the smallest genome sizes in Boraginaceae | |
| 小分子配体选择性结合RNA单链G凸起的机理研究 | Hegde, S. | N/A | Mechanistic Studies of Small Molecule Ligands Selective to RNA Single G Bulges | |
| 在人体颈动脉中，如果不进行层分离，无法揭示无应力状态。 | Hrubanova, A. | N/A | Stress-free state in human carotid arteries cannot be revealed without layer separation | |
| 使用中位数对单细胞DNA甲基化数据中的缺失值进行插补是一种直接且有效的方法。 | Tang, S. | N/A | Imputing not available values in single-cell DNA methylation data using the median is straightforward and effective | |
| 报告H：确定重复序列在基因组间的直系同源位置 | Bharadwaj, P. V. | N/A | REPORTH: Determining orthologous locations of repetitive sequences between genomes | |
| 利用药效团建模、QSAR、对接、ADMET、分子动力学和DFT分析发现天然MCL1抑制剂 | Das, U. | N/A | Discovery of Natural MCL1 Inhibitors using Pharmacophore modelling, QSAR, Docking, ADMET, Molecular Dynamics, and DFT Analysis | |
| 自动检测和提取生物医学论文表格中的关键资源 | Ozyurt, I. B. | N/A | Automatic Detection and Extraction of Key Resources from Tables in Biomedical Papers | |
| KinPFN：使用先验数据拟合网络的RNA折叠动力学贝叶斯近似 | Scheuer, D. | N/A | KinPFN: Bayesian Approximation of RNA FoldingKinetics using Prior-Data Fitted Networks | |
| 一种用于药物反应预测的多模态基因组知识蒸馏框架 | Ge, S. | N/A | A Multi-Modal Genomic Knowledge Distillation Framework for Drug Response Prediction | |
| 使用串联质谱库注释全扫描质谱数据 | Xing, S. | N/A | Annotating full-scan MS data using tandem MS libraries | |
| 评估AlphaFold2预测的白链结构域构建体的有效性。 | Mitic, I. | N/A | Assessing the Validity of Leucine Zipper Constructs Predicted in AlphaFold2. | |
| 利用微流控技术、延时相差显微镜和深度学习快速鉴定七种细菌种类 | Hallström, E. | N/A | Rapid identification of seven bacterial species using microfluidics, time-lapse phase-contrast microscopy, and deep learning | |
| 吉波替达辛和左利福达辛如何稳定细菌IIA型拓扑异构酶的DNA切割复合物？2. 单一移动金属机制。 | Nicholls, R. A. | N/A | How do gepotidacin and zolifodacin stabilize DNA-cleavage complexes with bacterial type IIA topoisomerases? 2. A Single Moving Metal Mechanism. | |
| PAR4反应性降低的小鼠表现出静脉血栓形成减少和血小板促凝活性降低 | Knauss, E. A. | N/A | Mice with Reduced PAR4 Reactivity show Decreased Venous Thrombosis and Platelet Procoagulant Activity | |
| 苔藓植物小立碗藓中生长素介导的基因激活作用 | Bascom, C. S. | N/A | The role of auxin-mediated gene activation in the bryophyte, Physcomitrium patens | |
| 蛋白质解聚酶HSP101对易聚集蛋白质HSA32的稳定作用，在维持拟南芥获得性耐热性中起着关键作用。 | Mitra, S. | N/A | Stabilization of HSA32, an aggregation-prone protein, by the protein disaggregase HSP101 plays a critical role in maintaining acquired thermotolerance in Arabidopsis | |
| APOE基因型和生物学年龄影响与生物能量学相关的多组学关联 | Ellis, D. S. | N/A | APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics | |
| 参数依赖性在可识别性中的应用：应用于Tauopathy网络建模参数化的FP-Fisher-KPP反应扩散方程 | Rahimabadi, A. | N/A | Parameter Dependence in Identifiability Applied to FP-Fisher-KPP Reaction-Diffusion Equations Parameterized for Tauopathy Network Modeling | |
| 在磁肌电图检测中识别单个运动单位活动 | Noury, N. | N/A | Detecting single motor-unit activity in magnetomyography | |
| 揭示星形胶质网络的功能连接性：AstroNet，一种结合图像处理的图重建算法 | Zonca, L. | N/A | Unveiling the Functional Connectivity of Astrocytic Networks with AstroNet, a Graph Reconstruction Algorithm Coupled to Image Processing | |
| 皮质微电路在强化学习中的区域特定信用分配 | Chevy, Q. | N/A | A Cortical Microcircuit for Region-Specific Credit Assignment in Reinforcement Learning | |
| 户外空气污染与青春期早期杏仁核亚区体积及分布有关 | Morrel, J. | N/A | Outdoor Air Pollution Relates to Amygdala Subregion Volume and Apportionment in Early Adolescents | |
| 预测性处理和知觉负荷在选择性视觉注意中的作用：对语义显著和较少显著干扰项的考察 | Ozsu, A. B. | N/A | The Role of Predictive Processing and Perceptual Load in Selective Visual Attention: An Examination with Semantically Salient and Less Salient Distractors | |
| 成纤维细胞将上皮营养感应与ILC2-簇细胞回路放大相连接 | Liao, C. | N/A | Telocytes link epithelial nutrient sensing with amplification of the ILC2-tuft cell circuit | |
| 了解溃疡性结肠炎患者对JAK抑制剂无反应的机制 | Melon-Ardanaz, E. | N/A | Understanding the mechanisms underlying the lack of response to Janus kinase inhibition in ulcerative colitis | |
| 盘尾丝虫空间蛋白质组学与多形性肿瘤显示蛋白质表达的局部和系统性失调 | Di Maggio, L. S. | N/A | Spatial proteomics of Onchocerca volvulus with pleomorphic neoplasms shows local and systemic dysregulation of protein expression | |
| 树木在单种和混种邻域中的生物量分配 | Perles-Garcia, M. D. | N/A | Biomass allocation of trees in response to mono- and heterospecific neighbourhoods | |
| 用于生长细根的碳的14C年龄反映了树木的碳状态。 | Hilman, B. | N/A | 14C-age of carbon used to grow fine roots reflects tree carbon status | |
| 缺氧导致珊瑚迅速死亡——对珊瑚礁构成的新兴危险威胁 | Dhillon, M. S. | N/A | Oxygen deprivation implicated in rapid coral mortality -- an emerging perilous threat to coral reefs | |
| 利用全球HLA数据提升iPSC配型库中的患者匹配效果 | Maiers, M. | N/A | Harnessing Global HLA Data for Enhanced Patient Matching in iPSC Haplobanks | |
| 野生小麦近缘种Aegilops comosa的染色体规模组装与注释 | Li, H. | N/A | Chromosome-scale assembly and annotation of the wildwheat relative Aegilops comosa | |
| 通过建模数字PCR的统计特征，改进废水流行病学中的推断 | Lison, A. | N/A | Improving inference in wastewater-based epidemiology by modelling the statistical features of digital PCR | |
| 用于罕见疾病药物再利用的知识图谱与可解释人工智能 | Perdomo-Quinteiro, P. | N/A | Knowledge Graphs and Explainable AI for Drug Repurposing on Rare Diseases | |
| 在单细胞和空间转录组学中评估替代多聚腺苷酸化检测方法 | Li, S. | N/A | Benchmarking alternative polyadenylation detection in single-cell and spatial transcriptomes | |
| DEMINERS通过提高纳米孔直接RNA测序的通量和准确性，实现了临床宏基因组学和比较转录组学分析。 | Song, J. | N/A | DEMINERS enables clinical metagenomics and comparative transcriptomic analysis by increasing throughput and accuracy of nanopore direct RNA sequencing | |
| 在生物语言模型中，跨生物分子模态的知识传递 | Prakash, M. | N/A | Bridging biomolecular modalities for knowledge transfer in bio-language models | |
| 吉波替达辛和左利福达辛如何稳定与细菌IIA型拓扑异构酶的DNA切割复合物？1. 金属结合位点的实验定义 | Morgan, H. | N/A | How do gepotidacin and zoliflodacin stabilize DNA-cleavage complexes with bacterial type IIA topoisomerases? 1. Experimental definition of metal binding sites | |
| 通过唾液生物标志物评估学术压力：皮质醇、IL-1β、CRP和IgA水平及其性别差异的多变量分析。 | Klagges, R. C. | N/A | Academic stress through salivary biomarkers: A multivariate analysis of cortisol, IL-1β, CRP, and IgA levels and their variations as a function of sex. | |
| 利用多环境全基因组关联分析方法研究自然感染条件下石果园中生物胁迫响应的遗传结构 | Serrie, M. | N/A | Investigating the genetic architecture of biotic stress response in stone fruit tree orchards under natural infections with a multi-environment GWAS approach | |
| 一项基于模型的元分析支持了新兴的共识观点，即抑制性神经元主导了BOLD-fMRI反应。 | Sundqvist, N. | N/A | A Model-Driven Meta-Analysis Supports the Emerging Consensus View that Inhibitory Neurons Dominate BOLD-fMRI Responses | |
| 通过结合新型竞争范式与现有范式揭示的小鼠社会能力与地位的刻板印象 | Liu, M. | N/A | Stereotype of mouse social competency and status revealed by a novel competition paradigm in combination with available paradigms | |
| 揭示帕金森病患者运动学习动态 | Kim, A. | N/A | Uncovering locomotor learning dynamics in people with Parkinson's disease | |
| 雄性附腺基因的快速启动子进化伴随着在密切相关的果蝇物种中的差异表达 | McQuarrie, D. W. J. | N/A | Rapid promoter evolution of male accessory gland genes is accompanied by divergent expression in closely related Drosophila species | |
| 尼日利亚养殖和野生非洲鲶鱼（Clarias gariepinus）的遗传多样性、种群结构和分化 | Sanda, M. K. | N/A | Genetic diversity, population structure and differentiation of farmed and wild African catfish (Clarias gariepinus) in Nigeria | |
| 依赖ATP的蛋白酶ClpYQ在枯草芽孢杆菌中降解细胞分裂蛋白DivIVA和Mbl | Lasnosky, T. D. | N/A | The ATP-dependent protease ClpYQ degrades cell division proteins DivIVA and Mbl in Bacillus subtilis | |
| 单羧酸转运蛋白转运甲状腺素的分子机制 | Tassinari, M. | N/A | Molecular mechanism of thyroxine transport by monocarboxylate transporters | |
| 利用大型语言模型和基因编辑元数据库探索基因编辑信息的管道 | Suzuki, T. | N/A | Pipeline to explore information on genome editing using large language models and genome editing meta-database | |
| 氟NMR研究氨基酸衍生的配体以研究TSPO | Duma, L. | N/A | Fluor NMR study of amino acid derived ligand to study TSPO | |
| 一个共同保守的基因对在螯合应激期间维持柄杆菌的铁稳态中起作用 | Ortiz, S. H. | N/A | A co-conserved gene pair supports Caulobacter iron homeostasis during chelation stress | |
| 大肠杆菌在合成废水和实际废水中的抗生素抗性发展特征 | Sutradhar, I. | N/A | Characterization of antibiotic resistance development of E. coli in synthetic and real wastewater | |
| 早期抗生素暴露会导致肠道菌群失调，这种失调与神经发育和神经再生有关。 | Zhao, Q. | N/A | Early-life antibiotic exposure leads to gut microbial dysbiosis associated with neurodevelopment and neuroregeneration | |
| Trim7在体内对小鼠诺如病毒感染的限制中没有作用。 | Annaswamy Srinivas, M. | N/A | Trim7 does not have a role in the restriction of murine norovirus infection in vivo | |
| 利用番茄废弃物提取物增强着色菌（Exiguobacterium aurantiacum）的色素生产：一种统计学方法 | Zeleke, B. | N/A | Enhancing pigment production by a chromogenic bacterium (Exiguobacterium aurantiacum) using tomato waste extract: A Statistical approach | |
| SMC 调节链霉菌中分离复合体中 ParB 的参与 | Pawlikiewicz, K. | N/A | SMC modulates ParB engagement in segregation complexes in Streptomyces | |
| 鉴定SLC35A1为多血清型重组腺相关病毒（AAV）载体转导的关键宿主因子 | Zhang, X. | N/A | Identification of SLC35A1 as an essential host factor for the transduction of multi-serotype recombinant adeno-associated virus (AAV) vectors | |
| 自发T2DM猕猴的多组学研究揭示肠道微生物通过上调过量棕榈酸的吸收促进T2DM | Liu, X. | N/A | Multi-omics investigation of spontaneous T2DM macaque reveals gut microbiota promote T2DM by up-regulating the absorption of excess palmitic acid | |
| 在持续念珠菌血症期间和基线时的血液培养物中，含有遗传多样性不同的白色念珠菌菌株，这些菌株在棘白菌素耐药性和毒力方面可能存在差异。 | Fleres, G. | N/A | Blood cultures at baseline and during persistent candidemia contain populations of genetically diverse Candida albicans strains that may differ in echinocandin tolerance and virulence | |
| 指导多物种有益生物膜的组装，以针对不良细菌 | Gueneau, V. | N/A | Guided assembly of multispecies positive biofilms targeting undesirable bacteria | |
| 肌球蛋白轻链3通过巨胞饮途径作为神经坏死病毒进入宿主细胞的受体 | Yao, L. | N/A | Myosin light chain 3 serves as a receptor for nervous necrosis virus entry into host cells via the macropinocytosis pathway | |
| 通过同时进行转录起始位点定位和甲基化定量来解析m6Am | Liu, J. F. | N/A | Decoding m6Am by simultaneous transcription-start mapping and methylation quantification | |
| 靶向降解HPV癌蛋白E6可减轻宫颈癌的肿瘤负担 | Smalley, T. B. | N/A | Targeted degradation of the HPV oncoprotein E6 reduces tumor burden in cervical cancer | |
| 一种用于多环四胺大环内酰胺表达和功能化的即插即用系统 | Gloeckle, A. | N/A | A Plug-and-Play System for Polycyclic Tetramate Macrolactam Expression and Functionalization | |
| 胚胎细胞起源及缺氧介导机制在PIK3CA驱动难治性血管畸形中的作用 | Torii, S. | N/A | Embryological cellular origins and hypoxia-mediated mechanisms in PIK3CA-Driven refractory vascular malformations | |
| 一种首创的双降解剂，针对Bcl-2/Bcl-xL，能够逆转HIV潜伏状态并消除体外储藏库 | Chang, L.-C. | N/A | A First-in-Class Dual Degrader of Bcl-2/Bcl-xL Reverses HIV Latency and Eliminates Ex Vivo Reservoirs | |
| rRNA特异性反义DNA和双链DNA触发rRNA生物合成，并对柑橘害虫Coccus hesperidum L.产生强大的杀虫效果。 | Oberemok, V. V. | N/A | rRNA-specific antisense DNA and dsDNA trigger rRNA biogenesis and cause potent insecticidal effect on insect pest Coccus hesperidum L. | |
| 鉴定眼病病原体棘阿米巴的包囊（四种）和滋养体（一种）的新诊断靶标 | Sundararaj, B. K. | N/A | Identification of new targets for the diagnosis of cysts (four) and trophozoites (one) of the eye pathogen Acanthamoeba | |
| 通过在人类线粒体中重构末端连接来生成线粒体DNA缺失 | sfeir, a. | N/A | Engineering mtDNA Deletions by Reconstituting End-Joining in Human Mitochondria | |
| 利用双特异性抗体实现mRNA靶向递送，将脂质纳米颗粒（LNPs）锚定于细胞表面标志物 | Dietmair, B. | N/A | Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell-surface markers | |
| 用于活细胞和体内成像的荧光阴离子菁染料质膜探针 | Danylchuk, D. I. | N/A | Fluorescent anionic cyanine plasma membrane probes for live cell and in vivo imaging | |
| 酮体生成通过脂肪氧化非依赖性机制保护免受MASLD-MASH进展的影响 | Queathem, E. D. | N/A | Ketogenesis protects against MASLD-MASH progression through fat oxidation-independent mechanisms | |
| METTL3-METTL14对Drosha-DGCR8介导的初级microRNA加工的影响 | Khadgi, B. B. | N/A | Effects of METTL3-METTL14 on primary microRNA processing by Drosha-DGCR8 | |
| 媒体品牌对头孢地尔盘扩散结果的影响 | DeMarco, M. G. | N/A | Impact of media brand on cefiderocol disk diffusion results | |
| TamL是拟杆菌门中维持外膜稳态的关键因子。 | Giovannercole, F. | N/A | TamL is a key player of the outer membrane homeostasis in Bacteroidetes. | |
| 实验室的可持续性：评估微孔板在PCR和片段检测中的重复使用性 | Berthelsen, A. L. | N/A | Sustainability in the laboratory: evaluating the reuseability of microtiter plates for PCR and fragment detection | |
| 从淡水斑马贻贝（Dreissena bugensis）中提取的湿粘附蛋白的鉴定与表征 | Obille, A. R. | N/A | Identification and characterization of a wet adhesive protein extracted from Dreissena bugensis, the freshwater quagga mussel | |
| 两个保守的精氨酸残基促进Suf家族半胱氨酸脱硫酶中的C-S键断裂和硫化物转移。 | Gogar, R. K. | N/A | Two conserved arginine residues facilitate C-S bond cleavage and persulfide transfer in Suf family cysteine desulfurases. | |
| 克拉伯病GALC错义变异的表达研究——基于残留酶活性、分泌量及神经鞘氨醇半乳糖苷水平的定量分析所获得的洞见 | Peng, H. | N/A | Expression study of Krabbe Disease GALC missense variants -- Insights from quantification profiles of residual enzyme activity, secretion and psychosine levels | |
| MLL/WDR5复合体招募KIF2C至中间体，以确保在有丝分裂期间微管解聚和收缩环压缩。 | Kataria, A. | N/A | MLL/WDR5 complex recruits KIF2C to midbody to ensure MT depolymerization and furrow compaction during cytokinesis | |
| 由Mnl1甘露糖苷酶和蛋白质二硫键异构酶双功能复合物启动的内质网相关降解（ERAD）过程 | Zhao, D. | N/A | Initiation of ERAD by the bifunctional complex of Mnl1 mannosidase and protein disulfide isomerase | |
| ZO-2支架机制调控Hippo信号通路。 | Liu, O. | N/A | A ZO-2 scaffolding mechanism regulates the Hippo signalling pathway. | |
| 细胞周期蛋白A和细胞周期蛋白B的mRNA转录后调控由Bruno 1和Cup介导，并在P-bodies内进一步微调。 | Bayer, L. V. | N/A | Post-transcriptional regulation of cyclin A and cyclin B mRNAs is mediated by Bruno 1 and Cup, and further fine-tuned within P-bodies | |
| 一种残留角膜缘干细胞的角膜缘干细胞缺乏小鼠模型 | Someya, H. | N/A | A limbal stem cell deficiency murine model with residual limbal stem cells | |
| 乳腺上皮细胞迁移与上皮-间质转化无关 | Chen, J. | N/A | Mammary Epithelial Migration is EMT-Independent | |
| 中性粒细胞表现出不同的迁移表型，这些表型受跨内皮迁移的调节。 | Schwartz, A. B. | N/A | Neutrophils exhibit distinct migration phenotypes that are modulated by transendothelial migration | |
| 柠檬酸合酶通过重构巨噬细胞的线粒体三羧酸循环，改善了脓毒症诱导的肺损伤。 | Sun, J. | N/A | Citrate synthase improves sepsis-induced lung injury by reconstructing the mitochondrial tricarboxylic acid cycle of macrophages | |
| 选择性静止期酵母细胞的协调分工扩大了休眠期种群的存活率 | Hsiao, K.-C. | N/A | Coordinated Division of Selective Stationary-Phase Yeast Cells Expands the Population Survivorship in Quiescence | |
| 可视化果蝇核形态和运输机制的发育动力学 | Shindo, Y. | N/A | Visualizing developmental dynamics of nuclear morphology and transport machinery in Drosophila | |
| 在诱导关节炎症后，肠道炎症和免疫转录物被沉默的证据 | Moran, M. M. | N/A | Evidence of Silencing of Intestinal Inflammatory and Immune Transcripts Following Induction of Joint Inflammation | |
| 小分子定向分化浸没培养的人鼻气道上皮用于呼吸疾病建模 | Dreyer, H. H. M. | N/A | Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modelling | |
| 物理信息椭球坐标编码隐式神经表示用于高分辨率体积宽视野显微镜 | Zhou, Y. | N/A | Physics-Informed Ellipsoidal Coordinate Encoding Implicit Neural Representation for high-resolution volumetric wide-field microscopy | |
| 羟基脲诱导内质网应激和细胞质蛋白聚集 | Sanchez-Molina, A. | N/A | Hydroxyurea induces ER stress and cytoplasmic protein aggregation | |
| 初级纤毛通过音猬信号通路塑造出生后星形胶质细胞的发育 | Bear, R. | N/A | Primary cilia shape postnatal astrocyte development through Sonic Hedgehog signaling | |
| 儿童在标准与奖励性Go/No-Go任务需求下大脑网络的差异重构 | Mitchell, M. E. | N/A | Differential reconfiguration of brain networks in children in response to standard versus rewarded go/no-go task demands | |
| 冬眠哺乳动物适应性生理转变背后的基因 | Drabeck, D. H. | N/A | Genes Underlying Adaptive Physiological Shifts Among Hibernating Mammals | |
| # BioRxiv 2024-10-16 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 长期胞外记录中神经活动追踪的通用框架 | Chaure, F. J. | N/A | General Framework for Tracking Neural Activity Over Long-Term Extracellular Recordings | |
| 池塘蜻蜓生态位的持久性，奠定了尽管选择变异，适应区依然稳定的基础。 | Gupta, A. | N/A | Persistence of the ecological niche in pond damselflies underlies a stable adaptive zone despite varying selection | |
| 鼻内自我扩增RNA SARS-CoV-2疫苗产生保护性呼吸和系统性免疫，并防止病毒传播。 | Jennewein, M. F. | N/A | Intranasal self-amplifying RNA SARS-CoV-2 vaccine produces protective respiratory and systemic immunity and prevents viral transmission | |
| 利用PlatinumCRISPr进行结构优化的sgRNA选择，以高效生成Cas9敲除 | Haussmann, I. U. | N/A | Structure-optimized sgRNA selection with PlatinumCRISPr for efficient Cas9 generation of knock-outs | |
| 全基因组测序数据中剪接改变变异的函数聚类揭示了罕见变异疾病的隐藏遗传性 | Wang, Y. | N/A | Functional clustering of splice-altering variants in whole genome sequencing data reveals hidden heritability in rare variant disorder | |
| 视觉空间动力学驱动沉浸式环境中的适应性社会学习 | Wu, C. M. | N/A | Visual-spatial dynamics drive adaptive social learning in immersive environments | |
| saseR：平衡偏移量解锁了RNA测序工具，实现快速、可扩展的差异使用、异常剪接和表达检索。 | Segers, A. | N/A | saseR: Juggling offsets unlocks RNA-seq tools for fast and Scalable differential usage, Aberrant Splicing and Expression Retrieval. | |
| 鉴定允许鲍氏不动杆菌维持高水平氟喹诺酮类耐药性的决定因素 | Hamami, E. | N/A | Identification of Determinants that Allow Maintenance of High-Level Fluoroquinolone Resistance in Acinetobacter baumannii | |
| 预测基于CRISPR-Cas9的表观基因组编辑效果 | Batra, S. S. | N/A | Predicting the effect of CRISPR-Cas9-based epigenome editing | |
| 通过免疫球蛋白A抑制上皮细胞增殖和肿瘤发生 | Donaldson, G. P. | N/A | Suppression of epithelial proliferation and tumorigenesis by immunoglobulin A | |
| 小鼠眶额皮层中信息内在价值的表征 | Bussell, J. J. | N/A | Representations of the intrinsic value of information in mouse orbitofrontal cortex | |
| 高效编码解释了神经响应稳态和刺激特异性适应 | Young, E. J. | N/A | Efficient coding explains neural response homeostasis and stimulus-specific adaptation | |
| 食物竞争影响繁殖干扰的强度及其对物种共存的后果。 | Cruz, M. A. | N/A | Competition for food affects the strength of reproductive interference and its consequences for species coexistence. | |
| 热带马利筋（Asclepias curassavica）的基因组和组织特异性转录组 | Feng, H. | N/A | Genome and tissue-specific transcriptome of the tropical milkweed (Asclepias curassavica) | |
| 靶向星形胶质细胞可减轻脊髓损伤后的神经病理性疼痛 | Zhao, Q. | N/A | Targeting resident astrocytes attenuates neuropathic pain after spinal cord injury | |
| 在酵母极性网络的补偿性进化过程中，全球基因重塑 | Kingma, E. | N/A | Global genetic rewiring during compensatory evolution in the yeast polarity network | |
| tRNA低修饰通过激活交叉途径控制系统促进烟曲霉对5-氟胞嘧啶的抗性。 | Bruch, A. | N/A | tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus. | |
| 在变量选择前的排列分析大大增强了OPLS分析在小样本群体中的鲁棒性。 | Ström, M. | N/A | The permutation analysis prior to variable selection greatly enhances robustness of OPLS analysis in small cohorts | |
| PRC2.1亚复合物通过调节CCND1和CCND2来抑制G1期进展 | Longhurst, A. D. | N/A | The PRC2.1 Subcomplex Opposes G1 Progression through Regulation of CCND1 and CCND2 | |
| 遗传多样性对跨越营养级的生态系统功能的影响与物种多样性一样大，但方向相反。 | Fargeot, L. | N/A | Genetic diversity affects ecosystem functions across trophic levels as much as species diversity, but in an opposite direction | |
| 自上而下起源的捕食者-猎物幂律的一般机制 | Mazzarisi, O. | N/A | General mechanisms for a top-down origin of the predator-prey power law | |
| AgeML：利用机器学习进行年龄建模 | Garcia Condado, J. | N/A | AgeML: Age modelling with Machine Learning | |
| 沃尔巴克氏菌增强了交配前和交配后早期隔离在螨虫中的匹配度 | Cruz, M. A. | N/A | Wolbachia strengthens the match between pre-mating and early post-mating isolation in spider mites | |
| BIMSA：利用内存处理加速长序列比对 | Alonso-Marin, A. | N/A | BIMSA: Accelerating Long Sequence Alignment Using Processing-In-Memory | |
| 大规模基因组重排的爆发式发生与非海洋环节动物的起源 | Vargas-Chavez, C. | N/A | A punctuated burst of massive genomic rearrangements and the origin of non-marine annelids | |
| 谷氨酸/GABA共传递的独特释放特性起到了对上丘脑输入的频率依赖性过滤作用。 | Hirai, H. | N/A | Distinct release properties of glutamate/GABA co-transmission serve as a frequency-dependent filtering of supramammillary inputs | |
| diaTracer能够对基于diaPASEF的蛋白质组学数据进行以光谱为中心的分析。 | Li, K. | N/A | diaTracer enables spectrum-centric analysis of diaPASEF proteomics data | |
| 规模至关重要：拥有数十亿（而非数百万）参数的大型语言模型更能与自然语言的神经表征相匹配。 | Hong, Z. | N/A | Scale matters: Large language models with billions (rather than millions) of parameters better match neural representations of natural language | |
| 提取后去甲肾上腺素激活会损害后续记忆，这取决于皮层-海马再激活的作用。 | Heinbockel, H. | N/A | Post-retrieval noradrenergic activation impairs subsequent memory depending on cortico-hippocampal reactivation | |
| 第三种情景记忆：情景熟悉度与项目熟悉度和回忆是不同的 | Addante, R. J. | N/A | A third kind of episodic memory: Context familiarity is distinct from item familiarity and recollection | |
| 北亚得里亚海（地中海）中入侵物种波氏多毛虫（多毛纲：缨鳃虫科）的大量存在 | Lezzi, M. | N/A | Massive presence of the invasive Polydora websteri (Polychaeta: Spionidae) in the North Adriatic Sea (Mediterranean Sea) | |
| 在正常听力中年成人中，增加的听力努力和耳蜗神经退化是导致噪音环境下言语感知行为缺陷的基础。 | Zink, M. E. | N/A | Increased listening effort and cochlear neural degeneration underlie behavioral deficits in speech perception in noise in normal hearing middle-aged adults. | |
| 大型蛋白质数据库揭示了结构互补性和功能局部性 | Szczerbiak, P. | N/A | Large protein databases reveal structural complementarity and functional locality | |
| 用于可视化多胺水平、摄取和分布的基因编码荧光传感器 | Tamura, R. | N/A | Genetically encoded fluorescent sensors for visualizing polyamine levels, uptake, and distribution | |
| 使用Glittr.org查找、比较并重复利用在线培训和教育材料 | van Geest, G. | N/A | Using Glittr.org to find, compare and re-use online materials for training and education | |
| 旁分泌拯救MYR1缺陷型刚地弓形虫突变体揭示了体内CRISPR筛选的局限性 | Torelli, F. | N/A | Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens | |
| ERGtools2 包：用于处理和分析视觉电生理数据的工具集 | Lindner, M. | N/A | The ERGtools2 package: A Toolset for Processing and Analysing Visual Electrophysiology Data | |
| 物体非刚性各向异性：皮层各向异性的高级知觉后果 | Maruya, A. | N/A | Anisotropy of object nonrigidity: High-level perceptual consequences of cortical anisotropy | |
| 果蝇piRNA通路中蛋白质相互作用的反复创新 | Riedelbauch, S. | N/A | Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway | |
| 数据驱动的改进抗体选择适宜免疫原评估 | Waury, K. | N/A | Data-driven evaluation of suitable immunogens for improved antibody selection | |
| 区域特异性扩散去极化驱动异常的癫痫后行为 | Mitlasoczki, B. | N/A | Region-specific spreading depolarization drives aberrant post-ictal behavior | |
| 生物学中的弱磁场效应是可以测量的——在不存在地磁场的情况下，非洲爪蟾胚胎发育加速。 | Lodesani, A. | N/A | Weak magnetic field effects in biology are measurable--accelerated Xenopus embryogenesis in the absence of the geomagnetic field | |
| 利用新型基因组资源和统计方法结合个体和群体测序数据，深入探讨过去和未来斑翅果蝇（Drosophila suzukii）的入侵情况 | Camus, L. | N/A | New insights into past and future invasion of Drosophila suzukii using novel genomic resources and statistical methods to combine individual and pool sequencing data | |
| 自催化循环的热力学一致性 | Kosc, T. | N/A | Thermodynamic consistency of autocatalytic cycles | |
| 印度荠菜（Rorippa indica）的种内基因组大小变异揭示了通过基因组扩增实现的热带适应性 | Han, T.-S. | N/A | Intraspecific genome size variation in Rorippa indica reveals a tropical adaptation by genomic enlargement | |
| 大鼠从空间距离到社交距离的信息传递：对后顶叶皮层在空间-社交整合中作用的影响 | Wise, T. B. | N/A | Information transfer from spatial to social distance in rats: implications for the role of the posterior parietal cortex in spatial-social integration | |
| 隔离节拍显著性对节奏听觉刺激效果的影响 | Von Handorf, K. M. | N/A | Isolating the effect of beat salience on rhythmic auditory stimulation outcomes | |
| 人类腹侧颞叶皮层功能侧化的个体差异：局部竞争与长程耦合 | Blauch, N. M. | N/A | Individual variation in the functional lateralization of human ventral temporal cortex: Local competition and long-range coupling | |
| 从动作到言语：内侧额叶皮层沿着尾侧到吻侧的预测误差梯度进行动作监控 | Dorokhova, L. | N/A | From movements to words: action monitoring in the medial frontal cortex along a caudal to rostral prediction error gradient | |
| 注意力网络在不确定情况下与策略精确性相关的默认模式网络中发挥作用。 | Yoon, D. | N/A | Attention networks engage the default mode network related to policy precision under uncertainty | |
| ZMYND11 在双模态调控潜伏基因和类脑剪接中发挥作用，以保障皮层发生 | Chang, X. | N/A | ZMYND11 Functions in Bimodal Regulation of Latent Genes and Brain-like Splicing to Safeguard Corticogenesis | |
| 脆性X综合征大鼠模型中受损的海马-前额叶网络：一项将神经动力学与自闭症样行为障碍联系起来的研究 | Ouardouz, M. | N/A | Disrupted Hippocampal-Prefrontal Networks In A Rat Model Of Fragile X Syndrome: A Study Linking Neural Dynamics To Autism-Like Behavioral Impairments | |
| 细胞外控制对新皮质神经元命运和多样性的影响 | Baumann, N. | N/A | Cell-extrinsic controls over neocortical neuron fate and diversity | |
| 快速且稳健的幼儿视觉物体识别 | Ayzenberg, V. | N/A | Fast and robust visual object recognition in young children | |
| 海马齿状回颗粒细胞亚型的多样化受Neuregulin1核反馈信号的调控。 | Rajebhosale, P. | N/A | Diversification of Dentate Gyrus Granule Cell Subtypes is Regulated by Neuregulin1 Nuclear Back Signaling. | |
| 增强小鼠发声的皮层-运动神经元投射 | Boyd, J. L. | N/A | Enhancing cortico-motoneuronal projections for vocalization in mice | |
| 光学分析突触和突触外位点的NMDA受体分子多样性 | Sicard, A. | N/A | Optical profiling of NMDA receptor molecular diversity at synaptic and extrasynaptic sites | |
| 一个自上而下的岛叶皮层回路，对非伤害性恐惧学习至关重要 | Han, J. | N/A | A top-down insular cortex circuit crucial for non-nociceptive fear learning | |
| CB1大麻素受体和囊泡谷氨酸转运体-3表达神经末梢在大脑皮层中与GABA能神经元相关的突触靶点和细胞来源 | Somogyi, P. | N/A | Synaptic targets and cellular sources of CB1 cannabinoid receptor and vesicular glutamate transporter-3 expressing nerve terminals in relation to GABAergic neurons in the human cerebral cortex | |
| 不同物种和多种生物因素下祖先脑干去甲肾上腺素能神经元的多样性 | Kelberman, M. A. | N/A | Diversity of ancestral brainstem noradrenergic neurons across species and multiple biological factors | |
| 欧亚松鸦（Garrulus glandarius）在食物储藏中的排除推理 | Hawkins, I. | N/A | Reasoning by exclusion in food-caching Eurasian jays (Garrulus glandarius) | |
| 老鼠在意什么？内外环境对雄性对雌性尖叫声的反应的影响 | Brunner, L. R. | N/A | What matters to a mouse? Effects of internal and external context on male vocal response to female squeaks | |
| 宽吻海豚的哨声变异及其社会声学互动 | Mustun, F. | N/A | Whistle variability and social acoustic interactions in bottlenose dolphins | |
| 规范性脑形态计量学模型在不同种族群体中的普适性 | Ge, R. | N/A | Generalizability of Normative Models of Brain Morphometry Across Distinct Ethnoracial Groups | |
| 奖励驱动的运动适应需要强大的基底神经节-皮质回路 | Leblois, A. | N/A | Reward-driven adaptation of movements requires strong recurrent basal ganglia-cortical loops | |
| 同步动力学是导致不规则新皮层放电的潜在机制。 | Pattadkal, J. J. | N/A | Synchrony dynamics underlie irregular neocortical spiking | |
| P73+ Cajal-Retzius细胞和Reelin在皮质形态发生中的不同贡献 | Elorriaga, V. | N/A | Differential contribution of P73+ Cajal-Retzius cells and Reelin to cortical morphogenesis | |
| 阿尔茨海默病早期糖萼系统健康及其与睡眠、认知和脑脊液生物标志物的关系。 | Ray, N. J. | N/A | Glymphatic system health in early Alzheimer's disease and its relationship to sleep, cognition and CSF biomarkers. | |
| 早期阿尔茨海默病中的淋巴系统健康及其与睡眠、认知和脑脊液生物标志物的关系。 | Ray, N. J. | N/A | Glymphatic system health in early Alzheimer's disease and its relationship to sleep, cognition and CSF biomarkers. | |
| 一个编码发声表达和接收的皮层位点 | Pomberger, T. | N/A | A Cortical Site that Encodes Vocal Expression and Reception | |
| 克里斯托弗·哥伦布家族成员的首个全面法医遗传学研究：他的曾曾孙 | Navarro Vera, I. | N/A | THE FIRST COMPREHENSIVE FORENSIC GENETIC STUDY OF A MEMBER OF CHRISTOPHER COLUMBUS' FAMILY: HIS GREAT-GREAT-GRANDSON | |
| 填补免疫治疗预测的空白：AGAE评分作为免疫检查点抑制剂反应的泛癌生物标志物 | Ye, B. | N/A | Bridging the Gap in Immunotherapy Prediction: The AGAE Score as a Pan Cancer Biomarker for Immune Checkpoint Inhibitor Response | |
| Galectin-4-KO小鼠中记忆缺陷、长期增强作用及海马突触可塑性 | Brocca, M. E. | N/A | Deficient Memory, Long-Term Potentiation and Hippocampal Synaptic Plasticity in Galectin-4-KO Mice. | |
| 阵发性慢波事件作为创伤后癫痫的诊断和预测生物标志物 | Van Hameren, G. | N/A | Paroxysmal Slow Wave Events as a diagnostic and predictive biomarker for post-traumatic epilepsy | |
| 快速发作性肌张力障碍-帕金森病中的网络机制 | Moeller, M. | N/A | Network mechanisms in rapid-onset dystonia-parkinsonism | |
| 跑步机步态训练促进不完全脊髓损伤后的皮质脊髓束可塑性 | Eisdorfer, J. T. | N/A | Treadmill step training promotes corticospinal tract plasticity after incomplete spinal cord injury | |
| 端粒长度与中老年参与者认知功能的关系：来自老龄研究中代表性不足社区的初步研究 | McLester-Davis, L. W. Y. | N/A | Telomere length and cognitive function among middle-aged and older participants from communities underrepresented in aging research: A preliminary study | |
| 在破伤风毒素诱发的癫痫大鼠模型中动态多日癫痫发作周期：节奏演变及其对预测的启示 | Zarei Eskikand, P. | N/A | Dynamic Multiday Seizure Cycles in a Tetanus Toxin Rat Model of Epilepsy: Evolving Rhythms and Implications for Prediction | |
| 隐含的运动既不引导目光跟随，也不引导意图归属。 | Görner, M. | N/A | Implied motion guides neither gaze following nor intention attribution | |
| 心磷脂通过阻止LPS与Caspase 4/11结合，抑制非经典炎症小体，从而减轻体内的内毒素血症 | Pizzuto, M. | N/A | Cardiolipin Inhibits the Noncanonical Inflammasome by Preventing LPS Binding to Caspase 4/11 to Mitigate Endotoxemia in Vivo | |
| 对埃塞俄比亚索马里地区新出现的皮肤利什曼病疫源地中一种独特的利什曼原虫热带种群体进行基因组特征分析 | Abera, A. | N/A | Genomic characterization of a unique population of Leishmania tropica in a new emerging focus of cutaneous leishmaniasis in Somali region of Ethiopia | |
| PAF1C在RNAPII转录延伸过程中，别构激活CDK12/13激酶。 | Lopez Martinez, D. | N/A | PAF1C allosterically activates CDK12/13 kinase during RNAPII transcript elongation | |
| 太阳辐射的漫射比和光谱特性的年变化：温带季风区域的云层效应 | Siriwardana, A. N. | N/A | Annual Variability in Diffuse Ratio and Spectral Characteristics of Solar Radiation: Cloud Effects in a Temperate Monsoon Region | |
| 植物性状数据来源的重要性：西北欧和潘诺尼亚生态区的共有物种在两个地区的性状值不同 | Sonkoly, J. | N/A | Origin of plant trait data matters: Shared species of Northwestern Europe and the Pannonian Ecoregion have different trait values in the two regions | |
| 一种可传播癌症对袋獾生命史特征的影响 | Strickland, K. | N/A | Effects of a transmissible cancer on life-history traits in Tasmanian devils | |
| 多样化的祖先揭示了真核生物起源时期复杂的共生相互作用 | Bernabeu, M. | N/A | Diverse ancestries reveal complex symbiotic interactions during eukaryogenesis | |
| 在密集环境中，大黄蜂会提高其学习飞行的海拔。 | Sonntag, A. | N/A | Bumblebees increase their learning flight altitude in dense environments | |
| 小鼠中的精细社会歧视：对阿尔茨海默病早期检测的启示 | Faure, L. M. | N/A | Fine Social Discrimination of Siblings in Mice: Implications for Early Detection of Alzheimer's Disease | |
| 野生环境中，更大的鱼群能做出更好、更快的集体决策 | Pacher, K. | N/A | Better and faster collective decisions by larger fish shoals in the wild | |
| 酒精诱导的DNA交联修复的机制性见解：范可尼贫血核酸酶Slx4-Xpf-Ercc1的作用 | Havlikova, J. | N/A | Mechanistic Insights into Alcohol-Induced DNA Crosslink Repair by the Fanconi Anemia Nuclease Slx4-Xpf-Ercc1 | |
| 利用冷冻电子断层扫描技术绘制海马体内神经元组织结构的分子图谱 | Glynn, C. | N/A | Charting the molecular landscape of neuronal organisation within the hippocampus using cryo electron tomography | |
| 无压力生物打印保留功能的人类原代和iPSC衍生的胰岛 | Poklar, M. | N/A | Stress-free Bioprinting of Human Primary and iPSC-derived Islets with Retained Functionality | |
| 全面肿瘤治疗场系统用于胶质母细胞瘤治疗的开发与验证：从原型设计到临床前评估 | Wang, X. | N/A | Development and Validation of a Comprehensive Tumor Treating Fields System for Glioblastoma Therapy: From Prototype Design to Preclinical Evaluation | |
| 在HA(pY)STACK中搜索磺酸酪氨酸（sY） | Tzvetkov, J. | N/A | Searching for Sulfotyrosines (sY) in a HA(pY)STACK | |
| 一种基于语义引导元路径方法的药物-靶标相互作用预测统一框架 | Li, H. | N/A | A unified framework for drug-target interaction prediction by semantic-guided meta-path method | |
| 非线性奇异值分解波束形成用于气泡超声成像 | Zhang, G. | N/A | Nonlinear Singular Value Decomposition Beamforming for Ultrasound Imaging of Gas Vesicles | |
| 慢性肥胖并不改变Tp53R270H/+小鼠的癌症生存率。 | Panzeri, I. | N/A | Chronic obesity does not alter cancer survival in Tp53R270H/+ mice | |
| PPARα-ERRα交叉对话缓解了与代谢功能障碍相关的脂肪肝疾病进展 | Antwi, M. B. | N/A | PPARalpha-ERRalpha crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression | |
| 预测无脊椎动物对化学物质的吸收和消除动力学：关于残差方差建模的技术说明 | van Lingen, H. J. | N/A | Predicting uptake and elimination kinetics of chemicals in invertebrates: a technicalnote on residual variance modeling | |
| GCS-H2对于生长至关重要，因为它在拟南芥异养组织中作为线粒体脂酰化的主要中继器发挥作用。 | Przybyla-Toscano, j. | N/A | GCS-H2 is essential for growth as it acts as the main relay for mitochondrial lipoylation in heterotrophic tissues of Arabidopsis thaliana | |
| 基于数据和知识的溶质载体功能景观 | Goldmann, U. | N/A | Data- and knowledge-derived functional landscape of human solute carriers | |
| 降低与激活负担基因电路相关的切换成本，有助于提高细胞群体的均一性和生产力。 | Henrion, L. | N/A | Lowering the switching cost related to the activation of burdensome gene circuits promotes cell population homogeneity and productivity | |
| 系统级分析揭示了由甲基营养菌（Bacillus methanolicus）以甲醇为原料生产L-谷氨酸及其脱羧产物γ-氨基丁酸的机制。 | Irla, M. | N/A | Systems-level analysis provides insights on methanol-based production of L-glutamate and its decarboxylation product γ-aminobutyric acid by Bacillus methanolicus | |
| 生物抗性可预测地改变微生物入侵模式 | Ye, X. | N/A | Biotic resistance predictably shifts microbial invasion regimes | |
| 人类大脑广泛激活的睡眠节律 | Wang, H. | N/A | Human Brain-Wide Activation of Sleep Rhythms | |
| Prefoldin 5 是一种微管相关蛋白，能够抑制Tau蛋白的聚集和神经毒性。 | Bisht, A. | N/A | Prefoldin 5 is a microtubule-associated protein that suppresses Tau-aggregation and neurotoxicity | |
| 大鼠暴露于自助餐厅饮食后腹侧被盖区的行为和神经改变 | Lalanza, J. F. | N/A | Behavioral and neural alterations of the ventral tegmental area by Cafeteria diet exposure in rats | |
| 眼动搜索任务与手动搜索任务中搜索成本与准确性之间的权衡 | Wagner, I. | N/A | Trade-off between search costs and accuracy in oculomotor and manual search tasks | |
| GLE1功能障碍会破坏细胞内稳态、空间组织以及周围轴突的分支。 | Zarybnicky, T. | N/A | GLE1 dysfunction compromises cellular homeostasis, spatial organization, and peripheral axon branching | |
| 荷兰未来关键鸟类物种的病原体传播丰富度 | Dellar, M. | N/A | The future abundance of key bird species for pathogen transmission in the Netherlands | |
| 使用GEV分布纳入气候极端情况可以提高物种分布模型（SDM）在范围边缘的表现。 | Fonteyn, W. | N/A | Incorporating climatic extremes using the GEV distribution improves SDM range edge performance | |
| 柳树中的一种新型下游因子取代了祖先的性别决定基因 | Wang, Y. | N/A | A novel downstream factor in willows replaces the ancestral sex determining gene | |
| TRENDY：基于Transformer的基因调控网络推断增强技术 | Tian, X. | N/A | TRENDY: Gene Regulatory Network Inference Enhanced by Transformer | |
| 214份玉米自交系叶片可及染色质区域的泛顺反子分析 | Zhu, Y. | N/A | Pan-cistrome analysis of the leaf accessible chromatin regions of 214 maize inbred lines | |
| 与UmV-KP4和UmV-KP6结构相关的小麦白粉菌蛋白对真菌具有毒性，并定义了真菌效应因子的新型结构家族。 | de Guillen, K. | N/A | Zymoseptoria tritici proteins structurally related to UmV-KP4 and UmV-KP6 are toxic to fungi, and define novel structural families of fungal effectors | |
| 钙调素调控的顺式和反式E-钙粘蛋白EC1-2相互作用在钙粘蛋白连接的形成、动态变化和可塑性中起着关键作用。 | Bron, P. | N/A | Calcium-modulated cis and trans E-cadherin EC1-2 interactions play a key role in formation, dynamics and plasticity of cadherin junctions | |
| ATP门控的P2x7受体是II型听觉神经的主要通道类型，对于听觉敏感性的传出控制和噪音保护是必需的。 | Liang, C. | N/A | ATP-gated P2x7 receptor is a major channel type at type II auditory nerves and required for hearing sensitivity efferent controlling and noise protection | |
| 在自我认知的元认知中，运动与结果表征的分离 | Charalampaki, A. | N/A | Dissociation of movement and outcome representations in metacognition of agency | |
| PEPITEM 三肽和拟肽：免疫介导条件下炎症的下一代调节剂 | Saviano, A. | N/A | PEPITEM Tripeptides and Peptidomimetics: Next-Generation Modulators of Inflammation in Immune-Mediated Conditions | |
| 真核生物中基于DAG的Dip2介导的特异性PKC信号轴的形成 | Shambhavi, S. | N/A | Emergence of Dip2-mediated Specific DAG-based PKC Signalling Axis in Eukaryotes | |
| Asgard古菌对真核生物起源的显著贡献 | Tobiasson, V. | N/A | Dominant contribution of Asgard archaea to eukaryogenesis | |
| EF-24的基因组发现揭示了白血病细胞中的抗肿瘤机制 | Singh, A. P. | N/A | Genomic Discovery of EF-24 Targets Unveils Antitumorigenic Mechanisms in Leukemia Cells | |
| 在膝关节屈曲和髋关节伸展任务中，股二头肌长头的远端激活程度更高，这反映了外周而非中枢运动单位特性的差异。 | Albarello, J. C. d. S. | N/A | Greater distal activation of the biceps femoris long head during knee flexion and hip extension tasks reflects differences in peripheral, not central, motor unit properties. | |
| 尽管mHTT聚集增加，Q175DN小鼠的海马备用容量增强 | Solem, M. A. | N/A | Enhanced Hippocampal Spare Capacity in Q175DN Mice Despite Elevated mHTT Aggregation | |
| 高阶转录组组织与RNA凝聚原理的综合分析 | Klobucar, T. | N/A | Integrative analysis of higher-order transcriptome organisation and RNA condensation principles | |
| 感知专长与注意力：基于深度神经网络的探索 | Das, S. | N/A | Perceptual Expertise and Attention: An Exploration using Deep Neural Networks | |
| 亚马逊生物文化遗产在气候变化下的状况 | Camara-Leret, R. | N/A | Amazonian biocultural heritage under climate change | |
| 孟加拉国代谢综合征患者血浆脂联素水平研究及治疗指征 | Parul, S. S. | N/A | Study of Plasma Adiponectin Levels in Patients with Metabolic Syndrome and Therapeutic Indication in Bangladesh | |
| 孕期压力、线粒体健康与妊娠周数之间的关系：来自美国和土耳其两项妊娠研究的发现 | Huang, Q. | N/A | Associations between prenatal distress, mitochondrial health, and gestational age: findings from two pregnancy studies in the USA and Turkey | |
| 元分析：使用磁性纳米颗粒提取的人血DNA、大肠杆菌gDNA和质粒的纯度 | Tjoa, S. E. E. | N/A | Meta-analysis: Purity of extracted human blood DNA, E. coli gDNA, and plasmid using magnetic nanoparticle | |
| 利用自体血液构建神经血管组织以模拟脑活动 | Arora, R. | N/A | Building neurovascular tissue from autologous blood for modeling brain-activity | |
| 表观遗传轨迹预测ACPA阳性个体临床类风湿性关节炎的发展：针对类风湿性关节炎预防的免疫反应靶向（TIP-RA） | Prideaux, E. B. | N/A | Epigenetic trajectory predicts development of clinical rheumatoid arthritis in ACPA+ individuals: Targeting Immune Responses for Prevention of Rheumatoid Arthritis (TIP-RA) | |
| 自主神经系统（ANS）-免疫网络在人类免疫缺陷病毒（HIV）感染者中的作用 | Mueller, B. R. | N/A | The Autonomic Nervous System (ANS)-Immune Network in People Living With HIV | |
| mRNA疫苗激发并由Omicron变种回忆的B细胞纵向分析揭示了广泛中和沙贝病毒的抗体 | Chen, X. | N/A | Longitudinal profiling of B cells primed by mRNA vaccine and recalled by Omicron variants uncovers antibodies broadly neutralizing sarbecoviruses | |
| RIG-I和MDA5协同识别登革病毒（DENV）的复制形式双链RNA，从而激活先天免疫反应。 | Ye, S. | N/A | RIG-I and MDA5 cooperatively recognize the DENV replicative-form dsRNA to activate innate immunity | |
| HSV-1感染改变了MAPT剪接，并促进了阿尔茨海默病神经模型中的Tau病理 | Ijezie, E. C. | N/A | HSV-1 Infection Alters MAPT Splicing and Promotes Tau Pathology in Neural Models of Alzheimer's Disease | |
| 关于噬菌体尾部终止蛋白和尾部完成蛋白：噬菌体T5尾部近端极端的结构 | Linares, R. | N/A | About bacteriophage tail terminator and tail completion proteins: structure of the proximal extremity of siphophage T5 tail | |
| 耐气甲烷菌利用海藻和海草的代谢物来推动海洋甲烷的排放。 | Hall, N. | N/A | Aerotolerant methanogens use seaweed and seagrass metabolites to drive marine methane emissions | |
| TaRTLEt：利用边缘检测的转录活性核糖开关追踪器 | Kshatriya, S. | N/A | TaRTLEt: Transcriptionally-active Riboswitch Tracer Leveraging Edge deTection | |
| 铜绿假单胞菌同时生产脂肽和鼠李糖脂生物表面活性剂：一种有前景的生物表面活性剂强化生物修复混合物 | Jacoby, M. d. R. | N/A | Simultaneous production of lipopeptide and rhamnolipid biosurfactants by Pseudomonas aeruginosa: A promising blend for biosurfactant-enhanced bioremediation | |
| 赋予抗真菌药物抗性的RNAi表观突变是可遗传的。 | Perez-Arques, C. | N/A | RNAi epimutations conferring antifungal drug resistance are inheritable | |
| 一种新型的PhoPQ增强的黏菌素耐药机制损害了铜绿假单胞菌的膜完整性 | Hsieh, Y.-Y. P. | N/A | A novel PhoPQ-potentiated mechanism of colistin resistance impairs membrane integrity in Pseudomonas aeruginosa | |
| 系统注释噬菌体基因组和质粒中的超变热点 | Egorov, A. A. | N/A | Systematic annotation of hyper-variability hotspots in phage genomes and plasmids | |
| 通过微血管3D血脑屏障模型揭示的恶性疟原虫出胞机制 | Piatti, L. | N/A | Pathogenic mechanisms of Plasmodium falciparum egress unveiled by a microvascular 3D blood-brain barrier model | |
| DDX3通过与PABP1及病毒基因组非翻译区的相互作用，调控日本脑炎病毒的帽依赖性翻译。 | Li, C. | N/A | DDX3 regulates the cap-independent translation of the Japanese encephalitis virus via its interactions with PABP1 and the untranslated regions of the viral genome | |
| 无壁细菌的FtsZ形成环状结构 | Kasai, T. | N/A | FtsZ of wall-less bacteria forms ring-like structures | |
| 单个MCP在希瓦氏菌（Shewanella putrefaciens）对浮游和结构化环境中游泳的进化适应中的作用 | Edelmann, D. B. | N/A | Role of a single MCP in evolutionary adaptation of Shewanella putrefaciens for swimming in planktonic and structured environments | |
| 强烈的隔离促进了自我毁灭的合作。 | Wen, L. | N/A | Strong segregation promotes self-destructive cooperation | |
| 从黄粉虫肠道中分离塑料降解微生物 | Reish, H. M. | N/A | Isolation of Plastic Digesting Microbes from the Gastrointestinal Tract of Tenebrio Molitor | |
| 共生肠道病毒组通过Th17细胞调节肠道营养感应 | Lin, F. | N/A | Commensal gut virome regulates intestinal nutrient sensing via Th17 cells | |
| 你是我的母亲吗？：当宿主遗传和肠道微生物在非洲化蜜蜂杂交种（Apis mellifera scutellata x sspp.）中讲述不同的系统发育故事时 | Soares, K. O. | N/A | Are you my mother?: When host genetics and gut microbiota tell different phylogenetic stories in the Africanized honey bee hybrid (Apis mellifera scutellata x sspp.) | |
| 前膜和包膜蛋白对蜱传脑炎病毒结构、致病性和趋向性的影响 | Rosendal, E. | N/A | The influence of the pre-membrane and envelope proteins on structure, pathogenicity and tropism of tick-borne encephalitis virus | |
| 丹佛动物园狮子、老虎和鬣狗群中的SARS-CoV-2疫情 | Gallichotte, E. N. | N/A | SARS-CoV-2 outbreak in lions, tigers and hyenas at Denver Zoo | |
| 利用dCas引导的邻近标记技术在曲霉菌中进行位点特异性染色质蛋白质组学研究。 | Strauss, J. | N/A | Locus-specific chromatin proteomics using dCas-guided proximity labelling in Aspergillus nidulans. | |
| TropD-Detector：一种基于CRISPR/LbCas12a的系统，用于快速且灵敏地筛选恰加斯病媒介和宿主中的克氏锥虫 | Ortiz-Rodriguez, L. A. | N/A | TropD-Detector: A CRISPR/LbCas12a-Based system for rapid and sensitive screening of Trypanosoma cruzi in Chagas vectors and reservoirs | |
| 一种以可重复性为重点的单细胞转录组病例对照研究的元分析方法揭示了稳健差异表达基因 | Nakatsuka, N. J. | N/A | A Reproducibility Focused Meta-Analysis Method for Single-Cell Transcriptomic Case-Control Studies Uncovers Robust Differentially Expressed Genes | |
| 坏死梭杆菌和变异梭杆菌是牛生殖道微生物群中的共生成员，可能在胎儿期就定殖于牛犊体内。 | Kilama, J. | N/A | Fusobacterium necrophorum and Fusobacterium varium are commensal members of the bovine reproductive microbiota and may colonize calf prenatally | |
| 多米尼加共和国非洲猪瘟主动和被动监测的最新情况 | Schambow, R. A. | N/A | An Update on Active and Passive Surveillance for African Swine Fever in the Dominican Republic | |
| 铜绿假单胞菌中由RNase E支架结构域介导的关键功能和关键相互作用 | Geslain, S. A. M. | N/A | Critical functions and key interactions mediated by the RNase E scaffolding domain in Pseudomonas aeruginosa | |
| 遗传兼容性和生态连通性推动抗生素抗性基因的传播 | Lund, D. | N/A | Genetic compatibility and ecological connectivity drive the dissemination of antibiotic resistance genes | |
| 主要病原菌流感嗜血杆菌在局部和全球范围内经历了普遍的重组和净化选择。 | MacAlasdair, N. | N/A | The major pathogen Haemophilus influenzae experiences pervasive recombination and purifying selection at local and global scales | |
| 利用单分子FRET技术对SARS-CoV-2 RNA聚合酶抑制剂的活性机制进行解析 | Groves, D. | N/A | Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET | |
| 活性炭通过重塑肠道微生物群的代谢来改善2型糖尿病 | Zhao, C.-X. | N/A | Activated carbon ameliorates type 2 diabetes via metabolic remodeling of the gut microbiota | |
| 利用黑曲霉通过液体发酵优化甘蔗糖蜜生产柠檬酸的工艺 | Amin, A. | N/A | Optimization of citric acid production from sugarcane molasses using Aspergillus niger by submerged Fermentation | |
| 基于昏迷模式的自动对焦技术在解析细菌冷休克反应期间的单细胞动力学方面展现出卓越性能 | Li, S. | N/A | Coma pattern-based autofocusing unlocks superior performance in unravelling single-cell dynamics during bacterial cold shock response | |
| RNA元件对于西尼罗河病毒诱导的核糖体移码的高效率是必需的 | Aleksashin, N. A. | N/A | RNA elements required for the high efficiency of West Nile Virus-induced ribosomal frameshifting | |
| 进一步表征和工程化一个11氨基酸基序以增强重组蛋白表达 | Bi, J. | N/A | Further characterization and engineering of a 11-amino acid motif for enhancing recombinant protein expression | |
| 一种流行病性Ralstonia solanacearum谱系的兴起及其宿主范围的扩展 | Evseeva, D. | N/A | Emergence and host range expansion of an epidemic lineage of Ralstonia solanacearum | |
| # BioRxiv 2024-10-15 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 单细胞动态揭示了心肌细胞在应激诱导下在肥大和凋亡之间的决策 | Chun, B. | N/A | Single-cell dynamics reveal a stress-induced decision between cardiomyocyte hypertrophy and apoptosis | |
| 学习增强了顶端树突中与行为相关的表征 | Benezra, S. E. | N/A | Learning enhances behaviorally relevant representations in apical dendrites | |
| 弥合前庭毛细胞功能与神经声音编码之间的差距 | Jaime Tobon, L. M. | N/A | Bridging the gap between presynaptic hair cell function and neural sound encoding | |
| 通过dropout增强从单细胞数据中改进基因调控网络的推断 | Zhu, H. | N/A | Improved gene regulatory network inference from single cell data with dropout augmentation | |
| SARS-CoV-2主蛋白酶对人类tRNA甲基转移酶TRMT1的识别与切割 | D'Oliviera, A. | N/A | Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease | |
| 功能性连接组学揭示了小鼠视觉皮层的一般连接规则 | Ding, Z. | N/A | Functional connectomics reveals general wiring rule in mouse visual cortex | |
| 前额叶皮层中感知偏见的表征 | Serrano-Fernandez, L. | N/A | Representation of a Perceptual Bias in the Prefrontal Cortex | |
| 发现自足月人类胎盘的多能细胞类型 | Vadakke-Madathil, S. | N/A | Discovery of a multipotent cell type from the term human placenta | |
| 研究狂犬病毒当代演化的分子钟假说 | Durrant, R. | N/A | Examining the molecular clock hypothesis for the contemporary evolution of the rabies virus | |
| 核仁动力学是由核糖体有序组装所决定的。 | Sheu-Gruttadauria, J. | N/A | Nucleolar dynamics are determined by the ordered assembly of the ribosome | |
| 功能性脑状态的能量与青少年起病的精神分裂症患者和健康人的认知功能相关 | Theis, N. | N/A | Energy of functional brain states correlates with cognition in adolescent-onset schizophrenia and healthy persons | |
| 谷胱甘肽加速细胞周期和细胞重编程在植物再生中的作用 | Lee, L. R. | N/A | Glutathione accelerates the cell cycle and cellular reprogramming in plant regeneration | |
| ERG1A K+通道通过调节C2C12肌管中的Calsequestrin1来增加细胞内钙浓度 | Hockerman, G. H. | N/A | ERG1A K+ Channel Increases Intracellular Calcium Concentration through Modulation of Calsequestrin1 in C2C12 Myotubes | |
| CAT Bridge：一种从多组学数据中高效挖掘基因-代谢物关联的工具包 | Yang, B. | N/A | CAT Bridge: an efficient toolkit for gene-metabolite association mining from multiomics Data | |
| 丘脑核团会聚核向海马CA1区的投射通过影响消退诱导的兴奋性突触分子重塑，参与了情境恐惧消退过程。 | Ziolkowska, M. | N/A | Projections from thalamic nucleus reuniens to hippocampal CA1 area participate in context fear extinction by affecting extinction-induced molecular remodeling of excitatory synapses | |
| 电影观看和静息状态下的结构-功能耦合与解耦：连接脑电图与结构影像的新见解 | Subramani, V. | N/A | Structure-function coupling and decoupling during movie-watching and resting-state: Novel insights bridging EEG and structural imaging | |
| 单细胞测序揭示了海龙科鱼类进化适应性的发育遗传基础 | Healey, H. M. | N/A | Single Cell Sequencing Provides Clues about the Developmental Genetic Basis of Evolutionary Adaptations in Syngnathid Fishes | |
| 一种良好的相互作用动力平衡引导转录因子枢纽到基因 | Fallacaro, S. | N/A | A fine kinetic balance of interactions directs transcription factor hubs to genes | |
| CRISPR-GPT：一种用于基因编辑实验自动化设计的LLM代理 | Qu, Y. | N/A | CRISPR-GPT: An LLM Agent for Automated Design of Gene-Editing Experiments | |
| 基因表达随机模型中细胞核与细胞质mRNA水平的联合分布：解析结果与参数推断 | Wang, Y. | N/A | Joint distribution of nuclear and cytoplasmic mRNA levels in stochastic models of gene expression: analytical results and parameter inference | |
| 移动EEG用于P3分析的预处理选择：系统文献综述与交互式探索 | Jacobsen, N. S. J. | N/A | Preprocessing Choices for P3 Analyses with Mobile EEG: A Systematic Literature Review and Interactive Exploration | |
| DNA复制过程中的模板切换是适应性基因扩增的常见来源。 | Chuong, J. | N/A | Template switching during DNA replication is a prevalent source of adaptive gene amplification | |
| 一刀切不可取：一种确定远程相机陷阱实际视野范围的新方法 | Carswell, B. M. | N/A | One size does not fit all: a novel approach for determining the Realised Viewshed Size for remote camera traps | |
| 使用HERRO校正的单倍型纳米孔读取进行端粒到端粒的分阶段基因组组装 | Stanojevic, D. | N/A | Telomere-to-Telomere Phased Genome Assembly Using HERRO-Corrected Simplex Nanopore Reads | |
| 发条猩猩：微小RNA、体温调节权衡与脑容量进化。 | Fromm, B. | N/A | Clockwork Orangutan: microRNAs, thermoregulatory tradeoffs, and the evolution of brain size. | |
| 内源性ZAP与寨卡病毒感染表型的改变相关 | Le, N. P. K. | N/A | Endogenous ZAP is associated with altered Zika virus infection phenotype | |
| 通过质谱语言的语义相似性实现未知代谢物的化学空间定位与注释 | Ji, H. | N/A | Chemical Space Localization for Unknown Metabolite Annotation via Semantic Similarity of Mass Spectral Language | |
| 癌症治疗期间细菌操纵子的扩展可缓解药物毒性 | Trepka, K. | N/A | Expansion of a bacterial operon during cancer treatment ameliorates drug toxicity | |
| 基于能的生化振荡器分析：结合键图与线性控制理论。 | Gawthrop, P. | N/A | Energy-based Analysis of Biochemical Oscillators Using Bond Graphs and Linear Control Theory. | |
| 对低温的转录反应在肠杆菌科中仅有微弱的保守性。 | Hoang, J. | N/A | The transcriptional response to low temperature is weakly conserved across the Enterobacteriaceae | |
| 规模的重要性：拥有数十亿（而非数百万）参数的大型语言模型更能与自然语言的神经表征相匹配。 | Hong, Z. | N/A | Scale matters: Large language models with billions (rather than millions) of parameters better match neural representations of natural language | |
| 主观感知相似性是否属于元认知？ | Moharramipour, A. | N/A | Is subjective perceptual similarity metacognitive? | |
| 果蝇造血龛通过由邻近组织和Slit-Robo信号调控的集体细胞迁移进行组装。 | Nelson, K. A. | N/A | The Drosophila hematopoietic niche assembles through collective cell migration controlled by neighbor tissues and Slit-Robo signaling | |
| 活动依赖的侧抑制使嗅球投射神经元的同步化成为可能 | Dalal, T. | N/A | Activity-dependent lateral inhibition enables the synchronization of olfactory bulb projection neurons | |
| AGS蛋白中GoLoco基序的进化修饰促进了海胆胚胎中微核的形成 | Emura, N. | N/A | The evolutionary modifications of a GoLoco motif in the AGS protein facilitate micromere formation in the sea urchin embryo | |
| 翼龙尾巴舵的新软组织数据显示出复杂、动态的张力使用方式，并扩展了其进化起源。 | Jagielska, N. | N/A | New soft tissue data of pterosaur tail vane reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins | |
| 当前机器学习模型在预测未表征蛋白质的酶功能方面存在的局限性 | de Crecy-Lagard, V. | N/A | Limitations of Current Machine-Learning Models in Predicting Enzymatic Functions for Uncharacterized Proteins | |
| 酒精通过刺激AMPK介导的对TORC1、p70/S6K和核糖体生物合成的抑制，诱导神经嵴中p53介导的细胞凋亡。 | Huang, Y. | N/A | Alcohol induces p53-mediated apoptosis in neural crest by stimulating the AMPK-mediated suppression of TORC1, p70/S6K, and ribosomal biogenesis. | |
| 靶向脂肪酸合酶抑制NF2/CDKN2A缺陷型恶性胸膜间皮瘤的肿瘤发展 | Karnan, S. | N/A | Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient malignant pleural mesothelioma | |
| 使用泛基因组进行基因型解析的拷贝数变异分析揭示了重复基因的同源特异性全球多样性和表达分化 | Ma, W. | N/A | Genotyping sequence-resolved copy-number variation using pangenomes reveals paralog-specific global diversity and expression divergence of duplicated genes | |
| 综合基因组学方法识别出酒精使用障碍个体大脑皮层的胶质细胞转录组失调及风险 | Warden, A. S. | N/A | Integrative genomics approach identifies glial transcriptomic dysregulation and risk in the cortex of individuals with Alcohol Use Disorder | |
| 按需发作促进癫痫治疗药物的快速筛选 | Chen, Y. | N/A | On-Demand Seizures Facilitate Rapid Screening of Therapeutics for Epilepsy | |
| 膜电位调节ERK活性和细胞增殖 | Sasaki, M. | N/A | Membrane potential modulates ERK activity and cell proliferation | |
| 肥胖中肌肉类型特异性自噬信号的调节：热量限制和运动的影响 | Ji, F. | N/A | Muscle Type-Specific Modulation of Autophagy Signaling in Obesity: Effects of Caloric Restriction and Exercise | |
| 高效多重非病毒工程化及多克隆γδ CAR-T细胞的扩增用于免疫治疗 | Bridge, J. | N/A | Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy | |
| 对广泛同意的“瓶中基因组”项目中的一对肿瘤-正常配对样本进行了广泛测序，以开发体细胞基准。 | McDaniel, J. H. | N/A | Extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair towards development of somatic benchmarks | |
| 克服突变KRAS表位翻译后修饰引起的免疫逃避，实现TCR-T细胞介导的抗肿瘤活性 | Lee, J. W. | N/A | Overcoming immune evasion from post-translational modification of a mutant KRAS epitope to achieve TCR-T cell-mediated antitumor activity | |
| 进化独特的N-糖基依赖性蛋白质质量控制系统在新型隐球菌的细胞适应性和胞外囊泡运输中发挥着关键作用 | Mota, C. | N/A | Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans | |
| 在斑马鱼中进行多行为表型分析，识别出一种新型非联想学习干扰因子，具有环境和人类相关性 | Leuthold, D. | N/A | Multi-behavioral phenotyping in zebrafish identifies a novel disruptor of non-associative learning with environmental and human relevance | |
| 芒果苷作为转甲状腺素纤维化的潜在抑制剂 | Grudinina, N. | N/A | Mangiferin As A Potential Inhibitor Of Transthyretin Fibrillogenesis | |
| 茶-1：解码生命的分子相互作用 | Chai Discovery, | N/A | Chai-1: Decoding the molecular interactions of life | |
| 在一组来自狗衰老项目的多样犬种队列中，转座子的DNA甲基化模式揭示了衰老差异。 | Mariner, B. L. | N/A | DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project | |
| 特定区域的扩散去极化驱动异常的癫痫后行为 | Mitlasozki, B. | N/A | Region-specific spreading depolarization drives aberrant post-ictal behavior | |
| 可可碱和阿糖苷的强效抗流感协同作用 | Lahiri, H. | N/A | Potent Anti-Influenza Synergistic Activity of Theobromine and Arainosine | |
| 不同皮层输入对丘脑初级和高级抑制性神经元的整合 | Puzzo, C. D. | N/A | Integration of distinct cortical inputs to primary and higher order inhibitory cells of the thalamus | |
| 甲虫-真菌互利共生中共生真菌的基因组多样化 | Huang, Y.-T. | N/A | Genome diversification of symbiotic fungi in beetle-fungus mutualistic symbiosis | |
| RNA测序深度指南用于研究可变剪接 | Tsoy, O. | N/A | RNA sequencing depth guidelines for the study of alternative splicing | |
| 人类大脑在首次使用迷幻蘑菇碱后发生变化 | Lyons, T. | N/A | Human brain changes after first psilocybin use | |
| 在果蝇中进行年龄和性别特异性的线粒体-核互作测试 | Garlovsky, M. D. | N/A | Testing for age- and sex- specific mitonuclear epistasis in Drosophila | |
| 活性氧解毒作用有助于脓肿分枝杆菌对抗生素的存活 | Bates, N. A. | N/A | Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival | |
| 多形拟杆菌（Bacteroides thetaiotaomicron）增强沃氏嗜胆菌（Bilophila wadsworthia）中的硫化氢生成。 | Davies, J. | N/A | Bacteroides thetaiotaomicron enhances H2S production in Bilophila wadsworthia | |
| 微管蛋白-2家族中的自抑制与激活的Beta-发夹机制 | Webb, S. | N/A | Beta-hairpin Mechanism of Autoinhibition and Activation in the Kinesin-2 Family | |
| 体外抑制宫颈CFTR离子通道可使宫颈粘液变稠 | Looney, R. J. | N/A | In vitro inhibition of the CFTR ion channel in the cervix thickens cervical mucus | |
| 通过铁死亡诱导识别靶向衰老细胞的脂质衰老剂 | Zhang, L. J. | N/A | Identification of lipid senolytics targeting senescent cells through ferroptosis induction | |
| HIF-1α 调控骨髓来源巨噬细胞的线粒体功能，但在组织驻留的肺泡巨噬细胞中则不然。 | Woods, P. S. | N/A | HIF-1α regulates mitochondrial function in bone marrow-derived macrophages, but not in tissue-resident alveolar macrophages | |
| DNA复制过程中超螺旋动态的空间组织 | Kusano, Y. | N/A | Spatial organization of supercoil dynamics during DNA replication | |
| 细胞类型解析的脑溶酶体蛋白图谱鉴定出SLC45A1相关疾病为溶酶体疾病 | Ghoochani, A. | N/A | Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder | |
| 可视化伴侣蛋白TRiC中β-微管蛋白折叠的成核、凝聚和传播过程 | Zhao, Y. | N/A | Visualizing nucleation, condensation and propagation of β-tubulin folding in chaperonin TRiC | |
| DIO-SPOTlight转基因小鼠用于功能性监测由整合应激反应调控的蛋白质合成 | Oliver, M. L. | N/A | DIO-SPOTlight Transgenic Mouse to Functionally Monitor Protein Synthesis Regulated by the Integrated Stress Response | |
| 通过配体功能化的CRISPR-Cas9靶向个体G四链体，揭示了转录依赖的功能响应 | Nuccio, S. P. | N/A | Individual G-quadruplex targeting with ligand-functionalized CRISPR-Cas9 uncovers transcriptional-dependent functional responses | |
| TRPM8通道通过依赖于雄激素受体（AR）的Scd1基因诱导以及对不饱和脂质含量的调节，控制高尔基体的形态。 | Wehbi, M. | N/A | TRPM8 channels control Golgi morphology through an AR-dependent induction of the Scd1 gene and modulation of unsaturated lipid content | |
| 多重单细胞成像揭示了在长期衰老诱导过程中，存在具有不同衰老表型的分化亚群。 | Sessions, G. A. | N/A | Multiplexed single-cell imaging reveals diverging subpopulations with distinct senescence phenotypes during long-term senescence induction. | |
| 异源表达及重组伊卡鲁加霉素发酵条件的优化 | Evers, J. K. | N/A | Heterologous expression and optimization of fermentation conditions for recombinant ikarugamycin production | |
| 隐私保护的大脑功能连接可视化 | Tao, Y. | N/A | Privacy-Preserving Visualization of Brain Functional Connectivity | |
| 牙菌斑中含有DNase I耐受的Z-DNA和G-四链体 | Evans, D. C. S. | N/A | Dental biofilms contain DNase I-resistant Z-DNA and G-quadruplexes | |
| 西南极半岛气候变化背景下的鸟类捕食者-猎物动态：范围界定综述 | Russell, T. M. | N/A | Avian predator-prey dynamics in a changing climate along the Western Antarctic Peninsula; a scoping review | |
| 自动变异解读：ClinVar致病变异在不同变异注释中的不一致遗传解读 | Chen, A. Y.-A. | N/A | Toward Automatic Variant Interpretation: Discordant Genetic Interpretation Across Variant Annotations for ClinVar Pathogenic Variants | |
| NeKo：一种基于先验知识自动构建网络的工具 | Ruscone, M. | N/A | NeKo: a tool for automatic network construction from prior knowledge | |
| NeKo：一种基于先验知识自动构建网络的工具 | Ruscone, M. | N/A | NeKo: a tool for automatic network construction from prior knowledge | |
| 在泛基因组图谱中高效地索引和查询注释 | Novak, A. M. | N/A | Efficient indexing and querying of annotations in a pangenome graph | |
| 异常糖基化揭示了Luminal B型和高干细胞指数基底型乳腺癌队列之间意想不到的临床结果差异 | Truter, M. | N/A | Aberrant glycosylation reveals unexpected clinical outcomes between Luminal B and Basal high stemness index breast cancer cohorts | |
| 无烟烟草与砷共同暴露下对口腔上皮细胞的分子和细胞表型程序的影响 | Das, S. | N/A | Molecular and cell phenotype programs in oral epithelial cells directed by co-exposure to arsenic and smokeless tobacco | |
| 靶向ZNF638可激活抗病毒免疫反应，并增强胶质母细胞瘤中的免疫检查点抑制作用 | Seetharam, D. | N/A | Targeting ZNF638 activates antiviral immune responses and potentiates immune checkpoint inhibition in glioblastoma | |
| 利用斑马鱼胚胎的表型观察，推进毒理学中的数据驱动分析 | Michaelis, P. | N/A | Leveraging zebrafish embryo phenotypic observations to advance data-driven analyses in toxicology | |
| 无创评估交感神经和副交感神经压力反射反应的时间动态 | Suarez-Roca, H. | N/A | Noninvasive Assessment of Temporal Dynamics in Sympathetic and Parasympathetic Baroreflex Responses | |
| 早引影响中的特征与信号：一项元研究 | Ioannidis, J. | N/A | Features and signals in precocious citation impact: a meta-research study | |
| 口腔-肠道-脑轴中的微生物组与毒力特征影响帕金森病和认知衰退的病理生理学 | Clasen, F. | N/A | Microbiome signatures of virulence in the oral-gut-brain axis influence Parkinson's disease and cognitive decline pathophysiology | |
| 巴基斯坦家禽中分离出的氟喹诺酮耐药和产超广谱β-内酰胺酶的沙门氏菌的出现 | Irfan, R. | N/A | The emergence of Fluoroquinolone resistant and Extended-spectrum beta-lactamase-producing Salmonella spp. isolated from Poultry in Pakistan | |
| 自催化循环的热力学一致性 | Kosc, T. | N/A | Thermodynamic consistency of autocatalytic cycles | |
| 生态时间序列中微妙的方法论差异会显著影响相关性检验结果。 | Cannistra, C. | N/A | Subtle methodological variations substantially impact correlation test results in ecological time series | |
| 细胞追踪与精确误差预测 | Betjes, M. A. | N/A | Cell tracking with accurate error prediction | |
| 深度学习提升人及植物组织蛋白质组中瓜氨酸化鉴定的精确度 | Gabriel, W. | N/A | Deep Learning Enhances Precision of Citrullination Identification in Human and Plant Tissue Proteomes | |
| 基于统计原理的单细胞转录组特征选择 | Dollinger, E. | N/A | Statistically principled feature selection for single cell transcriptomics | |
| TE-Seq：一种转座子注释与RNA-Seq分析流程 | Kelsey, M. M. G. | N/A | TE-Seq: A Transposable Element Annotation and RNA-Seq Pipeline | |
| AlphaFold2的训练集为其预测折叠转换构象提供了动力。 | Schafer, J. W. | N/A | AlphaFold2's training set powers its predictions of fold-switched conformations | |
| 综合型异构体解析的陆地棉（Gossypium barbadense）和海岛棉（Gossypium hirsutum）纤维转录组分析 | Tang, J. X. | N/A | Integrated Isoform-Resolved Transcriptomic Analysis of Gossypium barbadense and Gossypium hirsutum Fibers | |
| 放射治疗在人体肺部引发促血管生成信号 | Soulier, J. | N/A | Radiotherapy triggers pro-angiogenic signaling in human lung | |
| 苯肾上腺素引起的快速起始纤维化重塑和心室功能障碍涉及心肌细胞和成纤维细胞转录组的靶向重编程。 | Kimball, T. H. | N/A | Rapid onset fibrotic remodeling and ventricular dysfunction induced by phenylephrine involve targeted reprogramming of myocyte and fibroblast transcriptomes | |
| 与控制番茄柱头位置相关的新数量性状基因座 | Riccini, A. | N/A | New QTLs involved in the control of stigma position in tomato | |
| 进化与盗窃：Bryopsidales大型藻类和光合海蛞蝓中的状态转换丧失 | Havurinne, V. | N/A | Evolution and theft: loss of state transitions in Bryopsidales macroalgae and photosynthetic sea slugs | |
| 在拟南芥细胞分裂过程中，一种与Rab-Kinesin12融合的激酶模块耦合了囊泡递送与成膜体重塑。 | Elliott, L. | N/A | A Rab-Kinesin12-Fused kinase module couples vesicle delivery and phragmoplast remodelling during cytokinesis in Arabidopsis | |
| 一个全球资源约束模型，用于预测波动环境中的代谢通量动态 | Yuan, H. | N/A | A global resource constrained model to predict metabolic flux dynamics in fluctuating environments | |
| hu.MAP3.0：通过整合超过25,000个蛋白质组学实验构建的人类蛋白质复合物图谱 | Fischer, S. N. | N/A | hu.MAP3.0: Atlas of human protein complexes by integration of > 25,000 proteomic experiments | |
| 酿酒酵母中复制时序的调控 | Berners-Lee, R. | N/A | Regulation of replication timing in Saccharomyces cerevisiae | |
| 膝关节骨性关节炎的免疫学特征分析：调节性T细胞功能障碍作为疼痛的关键驱动因素 | Binvignat, M. | N/A | Immunological Profiling in Knee Osteoarthritis: Treg Dysfunction as Key Driver of Pain | |
| CD4+组织驻留记忆Th17细胞驱动IL-17A介导的脊柱关节炎关节病理 | Liu, F. | N/A | CD4+ tissue resident memory Th17 cells drive IL-17A-mediated joint pathology in Spondyloarthritis | |
| 胆固醇硫酸盐通过局部调节免疫反应性来防止母胎冲突。 | Hirotani, K. | N/A | Cholesterol sulfate prevents maternal-fetal conflict by locally modulating immune reactivity | |
| EZH2抑制剂tazemetostat可减轻HIV免疫逃逸，减少储库形成，并促进持久的CD8+ T细胞再生。 | Gramatica, A. | N/A | The EZH2 inhibitor tazemetostat mitigates HIV immune evasion, reduces reservoir formation, and promotes durable CD8+ T-cell revitalization | |
| 与全球报告的蜱传病毒相关的生态和社会经济因素 | Sambado, S. | N/A | Ecological and socioeconomic factors associated with globally reported tick-borne viruses | |
| 利用DNA代谢条形码技术研究蜜蜂在整个季节的采粉模式 | Larsen, S. N. | N/A | Investigating Honey Bee Pollen Foraging Patterns Across a Season Using DNA Metabarcoding | |
| 果蝇中雄性限制性选择的混合证据支持了基因内性冲突的存在。 | Thyagarajan, H. | N/A | Mixed evidence for intralocus sexual conflict from male-limited selection in Drosophila melanogaster. | |
| 氨基酸替换的适应度分布定律 | Sun, M. | N/A | A fitness distribution law for amino-acid replacements | |
| 预先暴露于压力可减少在严重环境扰动后社区和遗传多样性的丧失 | Xu, C. C. Y. | N/A | Pre-exposure to stress reduces loss of community and genetic diversity following severe environmental disturbance | |
| 配子结合基因中的平衡多态性与人类不孕不育无关 | Hart, M. W. | N/A | Balanced polymorphisms in gamete-binding genes are not associated with human infertility | |
| 小麦病原菌Zymoseptoria tritici在大陆传播过程中，其主要效应因子AvrStb6的多样化、丧失与毒力增强 | Sampaio, A. M. | N/A | Diversification, loss, and virulence gains of the major effector AvrStb6 during continental spread of the wheat pathogen Zymoseptoria tritici | |
| 气味感官测试与计算机模拟预测：高分辨率量化嗅觉动态的对比 | Abouelhamd, I. M. S. | N/A | Odor sensory tests vs. In-silico prediction for the high-definition quantification of olfaction dynamics | |
| 快速循环拉伸可诱导培养的人体肠平滑肌细胞产生合成性和促炎性表型，这可能改变其对相邻肠细胞的信号传递。 | Wolfson, S. M. | N/A | Rapid cyclic stretching induces synthetic, proinflammatory phenotypes in cultured human intestinal smooth muscle, with the potential to alter signaling to adjacent bowel cells | |
| 一种简化的、高通量的LC-MS分析方法，用于定量细胞培养中多肽的降解情况 | Rozans, S. J. | N/A | A Streamlined High-Throughput LC-MS Assay for Quantifying Peptide Degradation in Cell Culture | |
| 抗生素介导的新型纳米柱超表面阵列上的等离子共振 | Waitkus, J. | N/A | Antibiotic-Mediated Plasmonic Resonance on a Novel Nanopillar Metasurface Array | |
| 植物基和动物肉类的质地剖面分析与流变学特性 | Dunne, R. A. | N/A | Texture profile analysis and rheology of plant-based and animal meat | |
| MSFragger-DDA+ 通过全隔离窗口搜索提升肽段鉴定灵敏度 | Yu, F. | N/A | MSFragger-DDA+ Enhances Peptide Identification Sensitivity with Full Isolation Window Search | |
| DecoyFinder：同源RNA序列集中污染物的鉴定 | Zhu, M. | N/A | DecoyFinder: Identification of Contaminants in Sets of Homologous RNA Sequences | |
| 用于大鼠、鸡、猪和猴子单细胞及空间转录组学中细胞间通讯分析的配体-受体相互作用 | Sun, Y. | N/A | Ligand-Receptor Interactions for Cell-Cell Communication Analysis in Rat, Chicken, Pig, and Monkey Single-Cell and Spatial Transcriptomics | |
| 代谢物营养图谱指南（MeNu GUIDE）——一种揭示与疾病病因相互作用的代谢物营养图谱 | Wuerf, V. | N/A | MeNu GUIDE - a metabolite nutrition graph to uncover interactions with disease etiology | |
| 彗星碎片离子索引技术在增强肽段测序中的应用 | McGann, C. D. | N/A | Comet fragment-ion indexing for enhanced peptide sequencing | |
| 跨物种与物种特异性模型用于蛋白质熔解温度预测 | Garcia Lopez, S. | N/A | Cross-species vs species-specific models for protein melting temperature prediction | |
| 使用多阳性未标记自学习进行精确的细胞丰度定量 | Lin, Y. | N/A | Accurate Cell Abundance Quantification using Multi-positive and Unlabeled Self-learning | |
| 使用空间变换的概率多序列比对 | Garcia Lopez, S. | N/A | Probabilistic Multiple Sequence Alignment using Spatial Transformations | |
| 抗癌靶点组合：基于网络的信号传导方法用于发现 | Yavuz, B. R. | N/A | Anticancer Target Combinations: Network-Informed Signaling-Based Approach to Discovery | |
| SeqDance：一种用于表示蛋白质动态特性的蛋白质语言模型 | Hou, C. | N/A | SeqDance: A Protein Language Model for Representing Protein Dynamic Properties | |
| CytoLNCpred - 一种用于预测15种细胞系中胞质相关长编码RNA的计算方法 | Choudhury, S. | N/A | CytoLNCpred - A computational method for predicting cytoplasm associated long-coding RNAs in 15 cell-lines | |
| mTOR变体的激活揭示了类似PI3K的隐蔽口袋，扩展了别构、突变选择性抑制剂的设计 | Liu, Y. | N/A | mTOR variants activation discovers PI3K-like cryptic pocket, expanding allosteric, mutant-selective inhibitor designs | |
| 用于预测阳离子转运的近端小管芯片：药物转运蛋白表达与功能的动态洞察 | Petit, I. | N/A | Proximal Tubule-on-Chip for Predicting Cation Transport: Dynamic Insights into Drug Transporter Expression and Function | |
| 用于预测血脑屏障渗透性的注意力图神经网络模型 | Collins, J. W. | N/A | Attentive graph neural network models for the prediction of blood brain barrier permeability | |
| 用于预测血脑屏障渗透性的注意力图神经网络模型 | Collins, J. W. | N/A | Attentive graph neural network models for the prediction of blood brain barrier permeability | |
| 评估含有L-叔丁氨酸盐的合成大麻素受体激动剂的高效激动作用 | Lucaj, C. | N/A | Assessment of high-efficacy agonism in synthetic cannabinoid receptor agonists containing l-tert-leucinate | |
| 蚜虫的热生物学及其对农业和粮食安全的意义 | Villena, O. C. | N/A | Thermal biology of aphids and implications for agriculture and food security | |
| 调控小麦的棕色颖片和第一节间基因会导致木质化组织着色、木质化和抗病性的改变。 | Hua, L. | N/A | Manipulation of the brown glume and internode 1 gene leads to alterations in lignified tissue coloration, lignification, and pathogen resistance in wheat | |
| 芝麻（Sesamum indicum L.）原生质体分离、培养及微愈伤组织诱导的优化 | Debnath, A. J. | N/A | Optimisation of explant-specific isolation, culture, and micro-callus induction of sesame (Sesamum indicum L.) protoplasts | |
| 一种适用于GATEWAY兼容载体的新型工具箱，用于大豆复合植物中快速功能基因分析 | Mejias, J. | N/A | A novel toolbox of GATEWAY-compatible vectors for rapid functional gene analysis in soybean composite plants | |
| ABI5结合蛋白是ABA核心信号通路中关键组分的底物 | Finkelstein, R. R. | N/A | ABI5 Binding Proteins are substrates of key components in the ABA core signaling pathway | |
| 红色图像：一种针对直翅目（昆虫纲）采集标本使用近红外高光谱成像（NIR-HSI）的方法论和综合方法 | Tavares, G. C. | N/A | Images in red: A methodological and integrative approach for the usage of Near-infrared Hyperspectral Imaging (NIR-HSI) on collection specimens of Orthoptera (Insecta) | |
| 循环嫁接提高神经氨酸酶蛋白疫苗生产 | Rijal, P. | N/A | Loop Grafting Improves Neuraminidase Protein Vaccine Production | |
| 基于Alphafold的定量方案实现跨物种MHC-II限制性表位的泛预测 | Wang, S. | N/A | Pan-Prediction of MHC-II Restricted Epitopes Across Species via an Alphafold-based Quantification Scheme | |
| 外来哺乳动物破坏了本地蜣螂群落的共存关系 | Akashi, R. | N/A | Invasive mammals disrupt native dung beetle community coexistence | |
| 生物相互作用和环境过滤共同决定了热带雨林中蚯蚓的α多样性和β多样性。 | Goulpeau, A. | N/A | Biotic interactions and environmental filtering both determine earthworm alpha and beta diversity in tropical rainforests | |
| 佛罗里达花斑鸭在其体液先天免疫反应中表现出强烈的异质性。 | Ayala, A. J. | N/A | Wild Florida Mottled Ducks demonstrate strong heterogeneity in their humoral innate immune response | |
| 卵黄莺的鸣唱和鸣叫特征 | Cummings, W. | N/A | Characteristics of Vitelline Warbler songs and calls | |
| 肝脏异常对原位肝移植有重大影响。 | Chen, Y. | N/A | Abnormalities of the liver have big impacts on orthotopic liver transplantation | |
| 直接巨噬细胞共培养克服粘弹性水凝胶力学，促进成纤维细胞活化 | Astrab, L. R. | N/A | Direct M2 macrophage co-culture overrides viscoelastic hydrogel mechanics to promote fibroblast activation | |
| 纳米颗粒利用磁电效应来靶向并消灭癌细胞 | Bryant, J. M. | N/A | Nanoparticles use magnetoelectricity to target and eradicate cancer cells | |
| 鉴定肥厚型心肌病中的新型关键基因和信号通路：基于生物信息学和下一代测序数据分析的证据 | Vastrad, B. M. | N/A | Identification of novel key genes and signaling pathways in hypertrophic cardiomyopathy: evidence from bioinformatics and next generation sequencing data analysis | |
| 单分子成像中提高信噪比的革新策略：分子运动的影响 | Bu, G. | N/A | Innovative Strategies for Enhancing Signal-to-Noise Ratio in Single-molecule Imaging: The Influence of Molecular Motion | |
| 细胞竞争中超竞争者的物理特征 | Carpenter, L. C. | N/A | Physical traits of supercompetitors in cell competition | |
| 最优网络规模以实现最稳健的图灵模式 | Ahmad Shaberi, H. S. | N/A | Optimal network sizes for most robust Turing patterns | |
| 三维点扩散函数可以在潜在空间中进行自动编码 | Truedson, A. | N/A | The 3D point spread function can be autoencoded in latent space | |
| 长链非编码RNA FAM30A调控Musashi2-RUNX1轴，并在急性髓系白血病细胞中对白血病干细胞功能具有重要作用 | Calvo Sanchez, J. | N/A | The long non-coding RNA FAM30A regulates the Musashi2-RUNX1 axis and is required for LSC function in AML cells | |
| 视黄酸X受体信号传导介导软脑膜中癌细胞的脂质代谢 | Tong, X. | N/A | Retinoid X Receptor Signaling Mediates Cancer Cell Lipid Metabolism in the Leptomeninges | |
| 光引导的肌动蛋白聚合驱动原细胞的定向运动 | Matsubayashi, H. T. | N/A | Light-guided actin polymerization drives directed motility in protocells | |
| 大多数L1CAM并不与人类生物流体和诱导多能干细胞衍生的神经元中的细胞外囊泡相关联。 | Kadam, V. | N/A | Most L1CAM is not associated with extracellular vesicles in human biofluids and iPSC-derived neurons | |
| 广泛单层形成依赖于移植的人类iPSC衍生的视网膜色素上皮细胞的一个亚群 | Tessmer, K. | N/A | Extensive monolayer formation depends on a subpopulation of transplanted human iPSC-derived RPE cells | |
| 猪流感中单细胞抗原受体测序 | Gu, W. | N/A | Single-Cell Antigen Receptor Sequencing in Pigs with Influenza | |
| 直接对比核成像方法量化肿瘤CD8+ T细胞浸润 | Sandker, G. G. W. | N/A | Head-to-head comparison of nuclear imaging approaches to quantify tumor CD8+ T-cell infiltration | |
| EMC通过调节细胞膜流动性来促进膜蛋白的生物合成 | Berraquero, M. | N/A | EMC regulates cell membrane fluidity to facilitate biogenesis of membrane proteins | |
| 校对聚合酶中的直接和间接选择 | Husain, K. | N/A | Direct and indirect selection in a proofreading polymerase | |
| 稀有草原杂草残存种群间杂交优势：对恢复遗传学的启示 | Oakley, C. G. | N/A | Heterosis in crosses between remnant populations of a rare prairie forb: implications for restoration genetics | |
| 印度荠菜（Rorippa indica）的种内基因组大小变异揭示了通过基因组扩大实现的热带适应性 | Han, T.-S. | N/A | Intraspecific genome size variation in Rorippa indica reveals a tropical adaptation by genomic enlargement | |
| 基于机器视觉的遗传多样性小鼠脆弱性评估 | Sabnis, G. S. | N/A | Machine vision based frailty assessment for genetically diverse mice | |
| 首个近乎完整的猪基因组组装：实现更准确的遗传研究 | Cao, C. | N/A | The first near-complete genome assembly of pig: enabling more accurate genetic research | |
| 通过胺化作用调控明胶水凝胶界面的力学性能 | Adorno, G. R. | N/A | Shaping the mechanical properties of a gelatin hydrogel interface via amination | |
| 无模型机器学习方法的3D单分子定位显微技术 | Boland, M. d. | N/A | Model-free machine learning-based 3D single molecule localisation microscopy | |
| 3D超分辨率成像显示，PSD95在鼠脑中存在大量弥散的蛋白质超复合物。 | Daly, S. | N/A | 3D super-resolution imaging of PSD95 reveals an abundance of diffuse protein supercomplexes in the mouse brain | |
| 通过囊泡封装洞察时钟的精确性 | Li, A. Z. T. | N/A | Insights into a clock's fidelity through vesicular encapsulation | |
| 突变型p53通过依赖于甲羟戊酸途径的Rho/ROCK信号传导，调控癌细胞在复杂的三维环境中的侵袭。 | Guzman, A. | N/A | Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling. | |
| 肿瘤上的nsGSLs通过OT-I T细胞抑制体外抗肿瘤免疫反应，并在体内促进肿瘤生长。 | Verkerk, T. | N/A | nsGSLs on tumors impair anti-tumor immune responses by OT-I T cells in vitro and support tumor growth in vivo | |
| 神经细胞系中早老素-1和早老素-2的差异表达与调控 | Eccles, M. K. | N/A | Differential expression and modulation of presenilin-1 and presenilin-2 in neural cell lines | |
| 单壁碳纳米管上葡萄糖氧化酶的共价偶联用于葡萄糖传感 | Wang, H. | N/A | Covalent conjugation of glucose oxidase on single-walled carbon nanotubes for glucose sensing | |
| p62纤维的结构组织以及富含钙的p62包裹脂滴货物的细胞超微结构 | Berkamp, S. | N/A | Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo | |
| 体外模型模拟肺腺癌中肿瘤内皮细胞介导的免疫细胞重编程 | Krejbich, M. | N/A | In vitro models to mimic tumor endothelial cell-mediated immune cell reprogramming in lung adenocarcinoma | |
| TGF-β诱导非典型EMT以逃避肺腺癌休眠转移中的免疫机械监视 | Wang, Z. | N/A | TGF-β induces an atypical EMT to evade immune mechanosurveillance in lung adenocarcinoma dormant metastasis | |
| 单细胞和原位空间分析揭示了新生造血干细胞及其微环境的多样性 | Torcq, L. | N/A | Single-cell and in situ spatial analyses reveal the diversity of newly born hematopoietic stem cells and of their niches | |
| 在克隆性下，通用型基因型和高可塑性的进化是导致蓼科植物入侵的根本原因。 | Wang, S. | N/A | General purpose genotypes and evolution of higher plasticity in clonality underlie knotweed invasion | |
| 细胞形状噪声强度调控EMT相关细胞扩展过程中的形状动态 | Poenisch, W. | N/A | Cell shape noise strength regulates shape dynamics during EMT-associated cell spreading | |
| SERPINB5-TGF-β信号通路调节桥粒斑蛋白的膜定位，并改善寻常型天疱疮的皮肤水疱形成 | Rathod, M. | N/A | SERPINB5-TGF-β signalling modulates desmoplakin membrane localization and ameliorates pemphigus vulgaris skin blistering | |
| # BioRxiv 2024-10-14 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 愿意等待与内源性皮质醇的变化有关。 | Lukinova, E. | N/A | Willingness to wait covaries with endogenous variation in cortisol | |
| 选择性提取通过脑电图（EEG）神经模式的重现得以揭示。 | Moccia, A. | N/A | Selective retrieval revealed by electroencephalographic (EEG) neural pattern reinstatement | |
| 从英国医院分离出的肠外大肠杆菌（ExPEC）菌株中的毒力因子。 | Turton, J. F. | N/A | Virulence factors among isolates of extraintestinal Escherichia coli (ExPEC) from hospitals in the United Kingdom. | |
| 从非靶向代谢组学中识别和整合关键代谢反应 | Köhler, N. | N/A | Identification and Integration of Key-Metabolic Reactions from Untargeted Metabolomics | |
| 人类在行走时利用了横向稳定性和机动性之间的权衡 | Kulkarni, R. N. | N/A | Humans Exploit the Trade-Off Between Lateral Stability and Manoeuvrability During Walking | |
| GEF和GAP对Cdc42 GTPase循环的寡聚依赖性和协同调控 | Tschirpke, S. | N/A | Oligomerization-dependent and synergistic regulation of Cdc42 GTPase cycling by a GEF and a GAP | |
| 通过CRISPR/Cas9工程改造人类间充质干细胞系实现细胞外基质的组成性编辑 | Prithiviraj, S. | N/A | Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines | |
| 在伤害感受器中表达的钠通道对动作电位的阈下相、上升支和肩部有不同的贡献。 | Köster, P. A. | N/A | Sodium channels expressed in nociceptors contribute distinctly to action potential subthreshold phase, upstroke and shoulder | |
| ATP爆发是分枝杆菌抗生素致死性的主要驱动力 | Lodhiya, T. | N/A | ATP burst is the dominant driver of antibiotic lethality in Mycobacteria | |
| 在观看自然电影时，神经同步性表现出韧性驱动 | Ye, S. | N/A | Resilience-driven neural synchrony during naturalistic movie watching | |
| 在分化和癌症过程中，全球染色质重塑及对具有特定进化年龄基因的调控 | Raynal, F. | N/A | Global chromatin reorganization and regulation of genes with specific evolutionary ages during differentiation and cancer | |
| 使用DeepScence进行单细胞和空间衰老细胞检测 | Qu, Y. | N/A | Single-cell and spatial detection of senescent cells using DeepScence | |
| 植物细胞质膜桥通过内质网驱动的非完全胞质分裂形成 | Li, Z. P. | N/A | Plant plasmodesmata bridges form through ER-driven incomplete cytokinesis | |
| 全脑任务调制功能连接方法在fMRI任务连接组学中的比较 | Masharipov, R. | N/A | Comparison of whole-brain task-modulated functional connectivity methods for fMRI task connectomics | |
| 分子密度调控的结合位点成熟机制介导了Ndc80与着丝粒受体CENP-T的结合 | Tarasovetc, E. V. | N/A | Binding Site Maturation Modulated by Molecular Density Underlies Ndc80 Binding to Kinetochore Receptor CENP-T | |
| 使用压缩光场显微镜对体内动态进行千赫兹体积成像 | Wang, Z. | N/A | Kilohertz volumetric imaging of in-vivo dynamics using squeezed light field microscopy | |
| 固有无序的RNA结合基序协同作用以催化RNA折叠并驱动相分离 | Niedner-Boblenz, A. | N/A | Intrinsically disordered RNA-binding motifs cooperate to catalyze RNA folding and drive phase separation | |
| 自主唤醒的变异介导了空白思维事件的可报告性 | Boulakis, P. A. | N/A | Variations of autonomic arousal mediate the reportability of mind-blanking occurrences | |
| 一种良好的相互作用动力平衡引导转录因子枢纽向基因方向移动 | Fallacaro, S. | N/A | A fine kinetic balance of interactions directs transcription factor hubs to genes | |
| 在羊膜动物原肠胚形成过程中，左右组织者形成之前，双侧细胞流动呈现出不对称性。 | Asai, R. | N/A | Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation | |
| 植物肉和动物肉的机械和感官特征 | St. Pierre, S. R. | N/A | The mechanical and sensory signature of plant-based and animal meat | |
| 突触富集与同一神经元内两种对立多巴胺受体的动态调控 | Hiramatsu, S. | N/A | Synaptic enrichment and dynamic regulation of the two opposing dopamine receptors within the same neurons | |
| 多层次不可逆性揭示了人类大脑动力学中非平衡相互作用的高阶组织 | Nartallo-Kaluarachchi, R. | N/A | Multilevel irreversibility reveals higher-order organisation of non-equilibrium interactions in human brain dynamics | |
| 三相血栓形成模型：B型主动脉夹层的计算研究 | Gupta, I. | N/A | Triphasic Thrombosis Model: A Computational Study of Type B Aortic Dissection | |
| 蜂鸟传粉的趋同进化导致通过基因下调反复丧失花香 | Darragh, K. | N/A | The convergent evolution of hummingbird pollination results in repeated floral scent loss through gene downregulation | |
| 同时捕食多个猎物：功能反应线性关系的频率和种群动态效应 | Novak, M. | N/A | Feeding on multiple prey at a time:The frequency and population-dynamic effects of functional-response linearity | |
| 心脏肌钙蛋白T内源性无序连接区的结构动力学 | Cubuk, J. | N/A | Structural dynamics of the intrinsically disordered linker region of cardiac troponin T | |
| 南极地热土壤中表现出缺乏区域性栖息地泛化微生物 | Noell, S. E. | N/A | Antarctic geothermal soils exhibit an absence of regional habitat generalist microorganisms | |
| 一个组成性异染色质区域塑造了基因组组织并影响神经孢子菌的基因表达 | Reckard, A. T. | N/A | A Constitutive Heterochromatic Region Shapes Genome Organization and Impacts Gene Expression in Neurospora crassa | |
| 利用一种新颖的纤维追踪方法，研究从婴儿期到青春期上行听觉通路微观结构成熟的空间组织 | Lynch, K. M. | N/A | The spatial organization of ascending auditory pathway microstructural maturation from infancy through adolescence using a novel fiber tracking approach | |
| 鉴定枯草芽孢杆菌萌发受体蛋白GerAB中参与孢子吸水的关键残基 | Chen, L. | N/A | Identification of key residues in Bacillus subtilis germinant receptor protein GerAB involved in spore water uptake | |
| KATMAP：从敲低数据推断剪接因子活性及调控靶点 | McGurk, M. P. | N/A | KATMAP: Inferring splicing factor activity and regulatory targets from knockdown data | |
| 学习进度表与教学的共同演化，不仅促进了知识的累积，还催生了一种教师创新综合症 | Maisonneuve, L. | N/A | The coevolution of learning schedules and teaching enhances cumulative knowledge and drives a teacher-innovator syndrome | |
| ATG5的非经典作用及膜ATG8化在retromer组装和功能中的作用 | Paddar, M. A. | N/A | Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function | |
| 一种用于筛选体内蛋白水解开关的方法，这些开关能够介导Notch激活 | Baker, F. | N/A | An in vivo screen for proteolytic switches that can mediate Notch activation | |
| 在样地和植物水平上增加植物化学多样性对节肢动物群落有影响。 | Ojeda-Prieto, L. | N/A | Increasing intraspecific plant chemical diversity at plot and plant level affects arthropod communities | |
| 通过脑电图的不规则成分评估慢性疼痛中兴奋与抑制的平衡 | Gil Avila, C. | N/A | Assessing the balance between excitation and inhibition in chronic pain through the aperiodic component of EEG | |
| 力化学力调控停滞新生链的组成和命运 | Khan, D. | N/A | Mechanochemical forces regulate the composition and fate of stalled nascent chains | |
| 利用光遗传学技术对肌动蛋白细胞骨架和片足形成中的膜结构进行低温电子断层扫描 | Inaba, H. | N/A | Cryo-ET of actin cytoskeleton and membrane structure in lamellipodia formation using optogenetics | |
| FusionESP：通过融合蛋白质和化学知识，提升酶-底物配对预测的改进方法 | Du, Z. | N/A | FusionESP: Improved enzyme-substrate pair prediction by fusing protein and chemical knowledge | |
| 失眠评分：失眠的预测能力，对癌症具有高诊断和预后价值。 | Dan, X. | N/A | Insomnia score: predictive ability of insomnia, high-diagnostic and prognostic value for cancer. | |
| 不同血清型3肺炎链球菌中转化频率与感受态基因表达的变异 | Shambhu, S. | N/A | Variation in transformation frequency and competence gene expression among serotype 3 Streptococcus pneumoniae | |
| 学习是行为个体性的基本来源。 | Manna, R. | N/A | Learning is a fundamental source of behavioral individuality | |
| 脑尺度：在脉冲神经网络中实现可扩展的在线学习 | Wang, C. | N/A | BrainScale: Enabling Scalable Online Learning in Spiking Neural Networks | |
| 用于光刺激和电生理记录的铸造双色纳米光子神经探针 | Roszko, D. A. | N/A | Foundry-fabricated dual-color nanophotonic neural probes for photostimulation and electrophysiological recording | |
| 番茄中角黄素/玉米黄质合酶的表达改变了类胡萝卜素库，增强了维生素A原和风味挥发性物质 | Fu, J. | N/A | Capsanthin/Capsorubin Synthase Expression in Tomato Alters Carotenoid Pools, Enhancing Provitamin A and Flavor Volatiles | |
| FIGL1限制了拟南芥中减数分裂非交换事件的形成 | Charif, D. | N/A | FIGL1 limits the formation of meiotic non crossover events in Arabidopsis thaliana | |
| 婴儿开放大脑：一个婴儿脑部分割的开源仓库 | Feczko, E. J. | N/A | Baby Open Brains: An Open-Source Repository of Infant Brain Segmentations | |
| E(Q)AGNN-PPIS：用于蛋白质-蛋白质相互作用位点预测的注意力增强等变图神经网络 | Animesh, | N/A | E(Q)AGNN-PPIS: Attention Enhanced Equivariant Graph Neural Network for Protein-Protein Interaction Site Prediction | |
| 急性GARP耗竭会破坏囊泡运输，导致分拣、分泌和O-糖基化出现严重缺陷。 | Khakurel, A. | N/A | Acute GARP depletion disrupts vesicle transport leading to severe defects in sorting, secretion, and O-glycosylation | |
| 基准测试用于抗体设计的生成模型 & 探索序列排名的对数似然性 | Ucar, T. | N/A | Benchmarking Generative Models for Antibody Design & Exploring Log-Likelihood for Sequence Ranking | |
| 斑马鱼中rbfox1功能丧失导致bdnf/trkb2和pac1a表达失调，进而引起HPI轴过度激活、压力反应改变以及稳态过载。 | Leggieri, A. | N/A | rbfox1 loss of function in zebrafish leads to dysregulation in bdnf/trkb2 and pac1a expression resulting in HPI axis hyperactivation, altered stress response and allostatic overload | |
| 皮层阿尔法节律从自然场景背景中插值遮挡的运动 | Yeh, L.-C. | N/A | Cortical alpha rhythms interpolate occluded motion from natural scene context | |
| 利用迁移学习预测蛋白质-小分子相互作用 | Wang, J. | N/A | Leveraging Transfer Learning for Predicting Protein-Small Molecule Interactions | |
| 复杂多途径反应动力学分析：胰岛素二聚体解离 | Jeong, K. | N/A | Analysis of the dynamics of a complex, multipathway reaction: Insulin dimer dissociation | |
| 预融合AAA+重塑目标-SNARE蛋白复合物促进突触传递 | White, K. I. | N/A | Pre-fusion AAA+ remodeling of target-SNARE protein complexes enables synaptic transmission | |
| 不可或缺却又可有可无：肉桂酸4-羟化酶在水稻细胞壁木质化中的作用 | Supatmi, S. | N/A | Essential Yet Dispensable: The Role of CINNAMATE 4-HYDROXYLASE in Rice Cell Wall Lignification | |
| 两种亚麻品种的比较分析表明木脂素介导的盐胁迫适应性 | Debnath, A. J. | N/A | A comparative analysis between two flax varieties indicates lignan-mediated salt stress adaptiveness | |
| 过去100年育种过程中小麦根系水力特性的演变 | Baca Cabrera, J. C. | N/A | The evolution of root hydraulic traits in wheat over 100 years of breeding | |
| PhenoVision：一个用于从现场图像自动化生成并交付研究就绪植物物候数据的框架 | Dinnage, R. | N/A | PhenoVision: A framework for automating and delivering research-ready plant phenology data from field images | |
| 在致死温度限制以下的升高发育温度会降低埃及伊蚊的繁殖力。 | Peklanska, M. | N/A | Elevated developmental temperatures below the lethal limit reduce Aedes aegypti fertility | |
| 气候和睡眠模式中的纬度梯度影响感染了绿僵菌的果蝇黑腹果蝇的疾病结果 | Nan, M. | N/A | Latitudinal clines in climate and sleep patterns shape disease outcomes in Drosophila melanogaster infected by Metarhizium anisopliae | |
| FiNNpy 2.0：快速MEG源重建 | Crompton, D. | N/A | FiNNpy 2.0: Fast MEG source reconstruction | |
| 使用时间干扰正弦刺激选择性阻断C纤维传导以抑制内脏痛觉 | Zhang, S. | N/A | Suppression of Visceral Nociception by Selective C-Fiber Transmission Block Using Temporal Interference Sinusoidal Stimulation | |
| 膜与皮质附着蛋白的笼蔽作用可引发细胞对称性的破坏。 | Dar, S. | N/A | Caging of membrane-to-cortex attachment proteins can trigger cellular symmetry breaking | |
| 研究全氟己烷磺酸（PFHxS）对感觉运动和昼夜节律发育的影响 | Ferdous, S. R. | N/A | Examining perfluorohexane sulfonate (PFHxS) impacts on sensorimotor and circadian rhythm development | |
| FieldDino：用于植物育种研究的高通量生理形态表型分析的气孔特征 | Chaplin, E. D. | N/A | FieldDino: High-throughput physio-morphological phenotyping of stomatal characteristics for plant breeding research | |
| 晚更新世气候对林地草莓基因组的影响：一种多年生草本植物的故事 | Toivainen, T. | N/A | Late Quaternary climatic impact on the woodland strawberry genome: a perennial herb's tale | |
| 在芸苔属芥菜的同源多倍体中敲除脂肪酸延伸酶1同源等位基因会导致种子油中无法检测到芥酸。 | Patra, N. | N/A | Knockout of fatty acid elongase1 homeoalleles in amphidiploid Brassica juncea leads to undetectable erucic acid in seed oil | |
| 非侵入性、基于生物发光的时间动态可视化和量化拟南芥中的细菌感染 | Taks, N. W. | N/A | Non-invasive, bioluminescence-based visualization and quantification of bacterial infections in Arabidopsis over time | |
| 特定细菌分类群及其代谢物DHPS与阿尔茨海默病、帕金森病和肌萎缩侧索硬化症的关联。 | Ellis, J. C. | N/A | Specific Bacterial Taxa and Their Metabolite, DHPS, Linked to Alzheimers Disease, Parkinsons Disease, and Amyotrophic Lateral Sclerosis. | |
| 特定细菌分类群及其代谢物DHPS与阿尔茨海默病、帕金森病和肌萎缩侧索硬化症的关联。 | Christopher, C. J. | N/A | Specific Bacterial Taxa and Their Metabolite, DHPS, Linked to Alzheimers Disease, Parkinsons Disease, and Amyotrophic Lateral Sclerosis. | |
| 脂肪酸延长酶eloF的调控变化是果蝇prolongata中性别特异性信息素谱系进化的基础 | Yige, L. | N/A | Regulatory Changes in the Fatty Acid Elongase eloF Underlie the Evolution of Sex-specific Pheromone Profiles in Drosophila prolongata | |
| 深度相机捕捉到的产蛋母鸡在拍翅时的最大垂直高度 | Grebey, T. | N/A | Maximum vertical height during wing flapping of laying hens captured with a depth camera | |
| 芬太尼强化史对多步骤决策的影响具有性别特异性 | Garr, E. | N/A | Fentanyl reinforcement history has sex-specific effects on multi-step decision-making | |
| 用于即时伤口诊断的pH感应伤口敷料比色检测方法 | Cherifi, K. | N/A | Colorimetric detection methods of pH-sensing wound dressing for point-of-care wound diagnostics | |
| 探索蛋白质-DNA结合残基预测及利用深度学习进行一致性可解释性分析 | Liu, Y. | N/A | Exploring Protein-DNA Binding Residue Prediction and Consistent Interpretability Analysis Using Deep Learning | |
| 具有tau病理特征的特发性震颤在形态上与阿尔茨海默病和原发性年龄相关tau病变的种子无法区分。 | Saez-Calveras, N. | N/A | Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy | |
| 具有tau病理特征的特发性震颤在形态上与阿尔茨海默病和原发性年龄相关tau病变的种子无法区分。 | Saez-Calveras, N. | N/A | Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy | |
| 双特异性磷酸酶1（DUSP1）作为子痫前期的非侵入性循环生物标志物候选者 | Andrieu, J. | N/A | Dual specificity phosphate 1 (DUSP1) as a non-invasive circulating biomarker candidate in preeclampsia | |
| PERM1是否调节心脏收缩功能？一场数字游戏。 | Zaitsev, A. V. | N/A | Does PERM1 Regulate Systolic Cardiac Function? A Game of Numbers. | |
| 列当（Orobanche cumana Wallr）控制：向日葵杂交种的可持续性研究及寄生虫防护策略 | Khablak, S. | N/A | CONTROL OF OROBANCHE CUMANA WALLR: RESEARCH ON SUSTAINABILITY OF SUNFLOWER HYBRIDS AND STRATEGIES FOR PARASITE PROTECTION | |
| 人类大脑在首次使用迷幻蘑菇碱后发生变化 | Lyons, T. | N/A | Human brain changes after first psilocybin use | |
| IGF-1 影响癫痫性痉挛生成与缓解中的新皮质中间神经元连接性 | Ballester-Rosado, C. J. | N/A | IGF-1 IMPACTS NEOCORTICAL INTERNEURON CONNECTIVITY IN EPILEPTIC SPASM GENERATION AND RESOLUTION | |
| 轴突特异性微管调控驱动感觉神经元轴突的不对称再生 | Costa, A. C. | N/A | Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons | |
| TGF-β1/mTORC1信号轴在定义CTHRC1+病理性成纤维细胞的转录特征中起关键作用 | Wilson, J.-A. A. M. | N/A | Critical role for the TGF-β1/mTORC1 signalling axis in defining the transcriptional identity of CTHRC1+ pathologic fibroblasts | |
| 通过加权基因相关网络和生物信息学分析鉴定糖尿病相关创伤性脑损伤的关键基因和富集生物过程 | Saidu, U. F. | N/A | Identification of key genes and enriched biological processes in diabetes-associated traumatic brain injury through weighted gene correlation network and bioinformatics analysis | |
| 果蝇翅膀平面极化过程中细胞尺度信号传递的强有力证据 | Carayon, A. | N/A | Evidence for strong cell-scale signalling during planar polarisation in the Drosophila wing | |
| 敲除蛋白质组学揭示USP7通过AJUBA调节结直肠癌中的细胞间粘附 | Al-Eidan, A. | N/A | Knockdown proteomics reveals USP7 as a regulator of cell-cell adhesion in colorectal cancer via AJUBA | |
| 利用CRISPR条形码作为分子钟，以单细胞分辨率捕捉动态过程 | Andres-Lopez, Y. | N/A | Using CRISPR barcoding as a molecular clock to capture dynamic processes at single-cell resolution | |
| 人类成肌纤维FHOD3介导的肌动蛋白延伸对于心肌细胞肌节完整性是必需的。 | Valencia, D. A. | N/A | Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes | |
| 使用光学镊子对细胞力学进行稳健定量 | Rodenburg, W. S. | N/A | Robust quantification of cellular mechanics using optical tweezers | |
| 胆固醇通过共同的非经典结合位点差异性地调节阿片和毒蕈碱受体的活性 | Chetverikov, N. | N/A | Cholesterol differentially modulates the activity of opioid and muscarinic receptors via common non-canonical binding site | |
| 结核空洞中贝达喹啉扩散的动力学为耐药性的出现提供了契机。 | Bustion, A. E. | N/A | The kinetics of bedaquiline diffusion in tuberculous cavities opens a window for emergence of resistance. | |
| 回到未来：利用多基因本地适应的环境基因组选择 | Halpin-McCormick, A. | N/A | Back to the Future: Environmental genomic selection to take advantage of polygenic local adaptation | |
| 油菜黄单胞菌（Xanthomonas campestris pv. campestris）的四种细胞壁降解酶决定了细菌从排水孔逃逸到叶片脉管系统的过程。 | Paauw, M. | N/A | Four cell wall-degrading enzymes of Xanthomonas campestris pv. campestris determine bacterial escape from hydathodes to the leaf vasculature | |
| 葡萄糖依赖的糖鞘脂生物合成促进CD8+ T细胞功能和肿瘤控制 | Longo, J. | N/A | Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control | |
| 非协变存储效应：对放大随机适应性和人口统计波动的突变等位基因的正向选择 | Kim, Y. | N/A | Noncovarying storage effect: positive selection on mutant alleles that amplify random fitness and demographic fluctuations | |
| 在检测欧洲白蜡树（Fraxinus excelsior）对白蜡枯梢病耐受性方面，临时基因分型方法的局限性 | Szukala, A. | N/A | Limitations of ad hoc genotyping in detecting ash dieback tolerance in Fraxinus excelsior | |
| 人类小动脉染色质相互作用图谱揭示了血压遗传调控的新机制 | Liu, Y. | N/A | Chromatin interaction maps of human arterioles reveal new mechanisms for the genetic regulation of blood pressure | |
| CandyCollect：一种用于直接捕获和计数唾液外泌体的开放式微流控装置 | Pierce, C. | N/A | CandyCollect: An Open-Microfluidic Device for the Direct Capture and Enumeration of Salivary-Extracellular Vesicles | |
| CandyCollect：一种用于直接捕获和计数唾液外泌体的开放式微流控设备 | Pierce, C. A. | N/A | CandyCollect: An Open-Microfluidic Device for the Direct Capture and Enumeration of Salivary-Extracellular Vesicles | |
| 半监督组学因子分析（SOFA）能够从多组学数据中分离出已知的变异源和潜在因子。 | Capraz, T. | N/A | Semi-supervised Omics Factor Analysis (SOFA) disentangles known sources of variation from latent factors in multi-omics data | |
| prolfquapp - 一个用户友好的命令行工具，简化定量蛋白质组学中的差异表达分析 | Wolski, W. E. | N/A | prolfquapp - A User-Friendly Command-Line Tool Simplifying Differential Expression Analysis in Quantitative Proteomics | |
| 双途径共表达分析框架（D-CAF）能够从多组学时间序列数据中识别出新的昼夜节律调控 | Chuah, J. R. | N/A | Dual-Approach Co-expression Analysis Framework (D-CAF) Enables Identification of Novel Circadian Regulation From Multi-OmicTimeseries Data | |
| 肝细胞癌中关键基因的鉴定及CDK1靶向治疗药物：生物信息学与模拟研究 | Romero, R. | N/A | Identification of Hub Genes and CDK1-Targeting Therapeutics in Hepatocellular Carcinoma: Bioinformatics and Simulation Study | |
| 解读肠道微生物群对抑郁症的影响：基于社区水平的约束代谢建模方法 | Yuchen, Z. | N/A | Deciphering the Gut Microbiome's Influence on Depression: A Community-Level Constraint-Based Metabolic modelling Approach | |
| 基于基因扰动从scATAC-seq数据推断基因调控网络 | Shao, W. | N/A | Inferring Gene Regulatory Network Based on scATAC-seq Data with Gene Perturbation | |
| 雌激素受体1在肝星状细胞中的信号传导决定了对肝纤维化的抵抗性 | Li, T. | N/A | Estrogen Receptor 1 Signaling in Hepatic Stellate Cells Designates Resistance to Liver Fibrosis | |
| AZ12464237作为P2Y12受体的高亲和力非核苷酸拮抗剂放射性配体的表征 | Steen, J. | N/A | Characterization of AZ12464237 as a high affinity, non-nucleotide antagonist radioligand for the P2Y12 receptor | |
| 利用斑马鱼快速筛选方法鉴定潜在的败血症治疗药物 | Widder, M. W. | N/A | Identification of potential sepsis therapeutic drugs using a zebrafish rapid screening approach | |
| 缺乏证据表明锥状光感受器对人类夜间褪黑素抑制和警觉反应的贡献 | Fazlali, F. | N/A | Lack of evidence for the contribution of cone photoreceptors to human melatonin suppression and alerting response to light at night | |
| 作为有毒环境毒物在突触核蛋白病模型中的作用 | Shvachiy, L. | N/A | Lead as a toxic environmental toxicant in models of synucleinopathies | |
| 高原暴露对海平面居民骨骼肌线粒体亚细胞分布、超微结构及呼吸功能的影响 | Schytz, C. T. | N/A | Effect of high-altitude exposure on skeletal muscle mitochondrial subcellular distribution, ultrastructure and respiration in sea-level residents | |
| 在发育过程中，拟南芥细胞壁的纤维网络特性被用来调节其机械性能。 | Chen, S. | N/A | Mechanical properties are tuned during development with the fibrous network nature of the Arabidopsis cell wall | |
| MMM与CLCFM：基于摄影测量的三维点云重建方法，针对单株植物旋转拍摄的全方位图像 | Hayashi, A. | N/A | MMM and CLCFM: A 3D point cloud reconstruction method based on photogrammetry for all-around images taken by rotating an individual plant | |
| 使用不同LED光配方塑造羽衣甘蓝的形态和生理 | Scandola, S. | N/A | Shaping Kale Morphology and Physiology Using Different LED Light Recipes | |
| ERECTA家族信号在拟南芥胚珠起始过程中控制细胞命运的特化。 | Overholt, A. M. | N/A | ERECTA family signaling controls cell fate specification during ovule initiation in Arabidopsis. | |
| 不同环境胁迫下高粱（Sorghum bicolor）蜡质层动态变化揭示了与蜡质生成相关的信号模块 | Larson, M. | N/A | Wax bloom dynamics on Sorghum bicolor under different environmental stresses reveal signaling modules associated with wax production | |
| 孢粉素生物合成中的聚酮途径是陆地植物（胚胎植物）所特有的。 | Suh, D.-Y. | N/A | The polyketide pathway in sporopollenin biosynthesis is specific to land plants (Embryophyta) | |
| SOX10与微小RNA：解析它们在调控黑色素瘤可塑性中的相互作用 | Lai, X. | N/A | SOX10 and microRNAs: decoding their interplay in regulating melanoma plasticity | |
| AxSpA关节组织的特点是存在HLA-DR+组织驻留记忆（TRM）和杀伤细胞免疫球蛋白样受体（KIR）+ CD8+ T细胞亚群。 | Liu, F. | N/A | AxSpA joint tissue is characterised by HLA-DR+ tissue resident memory (TRM) and killer cell immunoglobulin-like receptor (KIR)+ CD8+ T cell subsets | |
| 几丁寡糖对多微生物脓毒症的保护作用通过N-乙酰-D-葡萄糖胺残基进行了精细调节。 | Patel, P. | N/A | Protection against Poly Microbial Sepsis by Chitin oligomersis fine tuned by N-Acetyl D-Glucosamine residues | |
| 多模态分析揭示CD4+CXCR5+PD-1- Tfh细胞作为人类弥漫性大B细胞淋巴瘤（DLBCL）中R-CHOP疗法反应的预后和预测生物标志物 | Yu, S. | N/A | Multi-modal profiling identifies CD4+CXCR5+PD-1- Tfh cells as prognostic and predictive biomarkers for response to R-CHOP therapy in human DLBCL | |
| 对果蝇中年龄和性别特异性线粒体-核互作的检测 | Garlovsky, M. D. | N/A | Testing for age- and sex- specific mitonuclear epistasis in Drosophila | |
| 解码基因表达在不同细胞和疾病状态下的序列决定因素 | Lal, A. | N/A | Decoding sequence determinants of gene expression in diverse cellular and disease states | |
| 儿童患者肺静脉狭窄的分子机制洞察 | Kalustian, A. B. | N/A | Insights into the Molecular Mechanism of Pulmonary Vein Stenosis in Pediatric Patients | |
| 器官芯片设备的毒物代谢动力学 | Hermann, N. G. | N/A | Toxicokinetics for organ-on-chip devices | |
| 使用加权非平行近端支持向量机的细菌菌株传播生物标志物的迁移学习模型 | Ugwu, U. O. | N/A | Transfer Learning Models for Bacterial Strain Dissemination Biomarkers using Weighted Non-Parallel Proximal Support Vector Machines | |
| 微生物组知识图谱（MicrobiomeKG）：通过知识图谱连接微生物组研究与宿主健康 | Goetz, S. | N/A | MicrobiomeKG: Bridging Microbiome Research and Host Health Through Knowledge Graphs | |
| 行动中的公平：四年迈向生物化学招聘中性别平等和种族多样化的旅程 | Christian, S. L. | N/A | Equity in Action: A Four-Year journey towards Gender Parity and Racial Diversity in Biochemistry Hiring | |
| 自由活动小鼠的高通量双光子体积脑成像 | Qian, L. | N/A | High-throughput two-photon volumetric brain imaging in freely moving mice | |
| 抑制作用解决西蒙冲突：来自脑电图解码的证据 | Lee, Y. S. | N/A | Inhibition Resolves Simon Conflict: Evidence from EEG Decoding | |
| 用于研究人体神经系统环路回路的Assembloid模型 | Miura, Y. | N/A | Assembloid model to study loop circuits of the human nervous system | |
| 通过高阶协方差矩阵分解实现高效的上位效应推断 | Shimagaki, K. S. | N/A | Efficient epistasis inference via higher-order covariance matrix factorization | |
| 人胰腺癌中磷酸化酪氨酸突变型结蛋白的鉴定 | Kendrick, N. C. | N/A | Identification of Phosphotyrosine-Mutant Desmin in Human Pancreatic Cancer | |
| 细胞内钙感知复合物CPKs/ECA1调控细胞质钙稳态以控制植物的渗透敏感性 | Liang, X. | N/A | An intracellular calcium sensory complex CPKs/ECA1 controls cytosolic calcium homeostasis for plant osmosensitivity | |
| 在节肢动物中诱导白内障揭示了晶状体蛋白如何促进生物玻璃的形成 | Mitra, A. T. | N/A | Cataract induction in an arthropod reveals how lens crystallins contribute to the formation of biological glass | |
| 在缺乏细胞死亡的情况下，选择性脑干神经元中的Tau负荷预测平衡缺陷的严重程度和性质。 | Zhu, Y. | N/A | Tau load in select brainstem neurons predicts the severity and nature of balance deficits in the absence of cell death | |
| 丙酮酸脱氢酶激酶1调控心肌细胞中甘油三酯的水解 | Atser, M. G. | N/A | Pyruvate dehydrogenase kinase 1 controls triacylglycerol hydrolysis in cardiomyocytes | |
| 未经治疗的非小细胞肺癌（NSCLC）光学成像揭示了与转移复发相关的变化 | Diaz, P. M. | N/A | Optical imaging of treatment-naive human NSCLC reveals changes associated with metastatic recurrence | |
| 己糖胺生物合成途径通过改变细胞骨架来调节转移性前列腺癌中的细胞增殖和迁移。 | Shakya, R. | N/A | The Hexosamine Biosynthetic Pathway alters the cytoskeleton to modulate cell proliferation and migration in metastatic prostate cancer | |
| 神经炎症与自发性高血压易中风大鼠的高血压相关脊髓病理学 | Noyan, H. | N/A | Neuroinflammation and Spinal Cord Pathology Associated with Hypertension in Spontaneously Hypertensive Stroke-Prone Rats | |
| 鉴定和靶向气道上皮中调节SARS-CoV-2-宿主相互作用的因子。 | Dirvin, B. G. | N/A | Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium. | |
| 卡莫氟类似物作为抗增殖剂、SARS-CoV-2主蛋白酶（Mpro）抑制剂和膜破裂诱导剂的合成与评估 | Gu, T. | N/A | Synthesis and Evaluation of Carmofur Analogs as Antiproliferative Agents, Inhibitors to the Main Protease (Mpro) of SARS-CoV-2, and Membrane Rupture-Inducing Agents | |
| 基于八个协变量对COVID-19患者疾病严重程度进行预测的机器学习算法比较评估 | Patel, T. S. | N/A | Comparative assessment of machine learning algorithms to predict severity of disease in COVID-19 patients based on eight cofactors | |
| 全球转录因子分析揭示了铜绿假单胞菌中调控网络的层次结构、协同作用及主要毒力调控因子 | Huang, J. | N/A | Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa | |
| 改进氨基酸生物合成途径的注释：GapMind 2024 | Price, M. N. | N/A | Improving the annotation of amino acid biosynthesis pathways: GapMind 2024 | |
| 膜结合型鸟苷酸环化酶COP5/HKR1改变纤毛搏动模式并影响衣藻在趋化过程中的细胞转向 | Strain, A. L. | N/A | Membrane-bound Guanylyl Cyclase COP5/HKR1 changes ciliary beat pattern and biases cell steering during chemotaxis in Chlamydomonas reinhardtii | |
| 农场暴露与人类母乳免疫特征和微生物群相关 | Swaney, M. H. | N/A | Farm exposure is associated with human breast milk immune profile and microbiome | |
| Cas9和雷帕霉素诱导的Cre重组酶的组成型表达促进了伯氏疟原虫中的条件性基因组编辑 | Das, S. | N/A | Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei | |
| 从辣木中合成银纳米颗粒：预防SARS-CoV-2污染水的潜力 | Shittu, M. O. | N/A | Green synthesized silver nanoparticles from Moringa: Potential for preventative treatment of SARS-CoV-2 contaminated water | |
| 核糖体蛋白bS1在正交mRNA起始密码子选择中的作用 | Boyko, K. V. | N/A | Role of ribosomal protein bS1 in orthogonal mRNA start codon selection | |
| 氧化性RNA损伤对SARS-CoV-2依赖RNA的RNA聚合酶体外复制的影响 | Akagawa, M. | N/A | Impact of an Oxidative RNA Lesion on in vitro Replication Catalyzed by SARS-CoV-2 RNA-dependent RNA Polymerase | |
| 大肠杆菌中的集体β-内酰胺耐药性：细胞死亡时释放β-内酰胺酶所致 | Gross, R. | N/A | Collective β-lactam resistance in Escherichia coli due to β-lactamase release upon cell death | |
| 免疫细胞促进感染肠道病毒D68的小鼠出现瘫痪性疾病 | Woods Acevedo, M. A. | N/A | Immune cells promote paralytic disease in mice infected with enterovirus D68 | |
| 杀手酵母在种植真菌蚂蚁花园中的普遍存在及新型杀手毒素Ksino的发现 | Bizarria, R. | N/A | The Prevalence of Killer Yeasts in the Gardens of Fungus-Growing Ants and the Discovery of Novel Killer Toxin named Ksino. | |
| 全基因组分析发现粪肠球菌中促进与卷曲乳杆菌种间竞争的基因 | Lam, L. N. | N/A | Genome-wide analysis of Enterococcus faecalis genes that facilitate interspecies competition with Lactobacillus crispatus | |
| 通过mRNA展示技术支持的机器学习模型评估环脱水酶LynD的底物范围 | Steude, E. G. | N/A | Assessing substrate scope of the cyclodehydratase LynD by mRNA display-enabled machine learning models | |
| 线粒体DNA突变连接Leigh综合征和颈动脉动脉粥样硬化：一项关于共享遗传途径的研究 | Sharma, A. | N/A | Mitochondrial DNA Mutations Linking Leigh Syndrome and Carotid Atherosclerosis: A Study of Shared Genetic Pathways | |
| 多形拟杆菌（Bacteroides thetaiotaomicron）增强了沃氏嗜胆菌（Bilophila wadsworthia）中硫化氢的产生。 | Davies, J. | N/A | Bacteroides thetaiotaomicron enhances H2S production in Bilophila wadsworthia | |
| 实时高分辨率显微镜揭示了单细胞裂解如何塑造生物膜基质形态发生 | Squyres, G. R. | N/A | Real-time high-resolution microscopy reveals how single-cell lysis shapes biofilm matrix morphogenesis | |
| 香草木犀素抑制登革病毒NS5甲基转移酶的机制性见解 | Bhutkar, M. | N/A | Mechanistic insights into the inhibition of dengue virus NS5 methyltransferase by herbacetin | |
| 芜菁黄花叶病毒颗粒的结构。读取通域是如何暴露在衣壳表面的？ | Lai-Kee-Him, J. | N/A | Structure of the turnip yellows virus particles. How is the readthrough domain exposed on the capsid surface? | |
| 真菌病原体球孢子菌形态发育的转录组图谱揭示了关键阶段富集的转录本 | Homer, C. M. | N/A | Transcriptomic atlas of the morphologic development of the fungal pathogen Coccidioides reveals key phase-enriched transcripts | |
| 细菌鉴定和感染性疾病诊断中的16S rRNA基因测序 | Li, M.-N. | N/A | 16S rRNA gene sequencing for bacterial identification and infectious disease diagnosis | |
| 铜绿假单胞菌金属应答TonB依赖转运蛋白的特性分析 | Ferry, M. | N/A | Characterisation of Pseudomonas aeruginosas metal-responsive TonB-dependent transporters | |
| 致病性相关黏附素通过生物膜形成驱动共生菌在蜜蜂肠道中的定殖 | Lariviere, P. J. | N/A | Virulence-linked adhesin drives mutualist colonization of the bee gut via biofilm formation | |
| 肝脏CYP4A自噬-溶酶体降解（ALD）：自噬受体SQSTM1/p62通过一个不常见的靶点相互作用位点发挥主要作用 | He, L. | N/A | Liver CYP4A autophagic-lysosomal degradation (ALD): A major role for the autophagic receptor SQSTM1/p62 through an uncommon target interaction site | |
| # BioRxiv 2024-10-13 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 负选择可能导致转移性结直肠癌中染色体核型显著改变但总体稳定。 | Cross, W. | N/A | Negative selection may cause grossly altered but broadly stable karyotypes in metastatic colorectal cancer | |
| 一群多样化的顶盖前蓝斑神经元控制着觉醒和探索行为 | Luskin, A. T. | N/A | A diverse population of pericoerulear neurons controls arousal and exploratory behaviors | |
| 神经-GSTH：一种几何散射与持久同源性框架，用于揭示神经活动中的时空特征 | Bhaskar, D. | N/A | Neuro-GSTH: A Geometric Scattering and Persistent Homology Framework for Uncovering Spatiotemporal Signatures in Neural Activity | |
| 成纤维细胞网络是毛囊再生中不可或缺的干细胞龛组成部分。 | Canella, M. | N/A | Telocyte networks are an essential stem cell niche component in hair follicle regeneration | |
| 化学熵的动能与能量牵引 | Baker, J. | N/A | The Kinetic and Energetic Pull of Chemical Entropy | |
| MpmiR319促进苔藓植物小立碗藓（Marchantia polymorpha）中珠芽/珠芽杯的形成。 | Futagami, K. | N/A | MpmiR319 promotes gemma/gemma cup formation in the Liverwort Marchantia polymorpha | |
| reconcILS：一种允许不完全谱系分选的基因树-物种树比对算法 | Mishra, S. | N/A | reconcILS: A gene tree-species tree reconciliation algorithm that allows for incomplete lineage sorting | |
| IIHP：阻塞性睡眠呼吸暂停中的智能高血压事件预测 | Halimi Milani, O. | N/A | IIHP: Intelligent Incident Hypertension Prediction in Obstructive Sleep Apnea | |
| 量子热力学、嵌套共振结构与生命的熵稳定性 | Baker, J. | N/A | Quantized Thermodynamics, Nested Resonant Structures, and the Entropic Stability of Life | |
| 细胞死亡的理论基础 | Himeoka, Y. | N/A | A theoretical basis for cell death | |
| 目标简化与循环消除加速强化学习并模拟人类大脑在目标导向学习中的活动 | Cheng, H. | N/A | Goal Reduction with Loop-Removal Accelerates RL and Models Human Brain Activity in Goal-Directed Learning | |
| 星形胶质细胞吞噬作用对皮层纹状体突触的选择性调控 | Kim, J.-y. | N/A | Selective regulation of corticostriatal synapses by astrocytic phagocytosis | |
| 目标距离视觉视野和年龄增长影响视觉搜索效率：行为和建模证据 | Akbari, F. | N/A | Target Distance from the Visual Field and Increased Age Affect Visual Search Efficiency: Behavioral and Modeling Evidence | |
| 果蝇EcR-Hippo组分Taiman通过调控Dally样糖蛋白和Wg梯度促进上皮细胞适应性 | Schweibenz, C. K. | N/A | The Drosophila EcR-Hippo component Taiman promotes epithelial cell fitness by control of the Dally-like glypican and Wg gradient | |
| 营养状态依赖的果蝇胰岛素产生细胞的调节 | Singh Bisen, R. | N/A | Nutritional state-dependent modulation of Insulin-Producing Cells in Drosophila | |
| 氟康唑抗性在耳念珠菌III株中的短期进化和传播模式 | Cancino-Munoz, I. | N/A | Short-Term Evolution and Dispersal Patterns of fluconazole-resistance in Candida auris clade III | |
| 鉴定牛奶过敏发展的潜在炎症标志物 | Hendrickx, D. M. | N/A | Identification of potential inflammation markers for outgrowth of cow's milk allergy | |
| 疟原虫需要一种不同的血红素加氧酶来促进顶复合物基因的表达和生物发生。 | Blackwell, A. M. | N/A | Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis | |
| RNADiffFold：使用离散扩散模型进行RNA二级结构预测的生成方法 | Wang, Z. | N/A | RNADiffFold: Generative RNA Secondary Structure Prediction using Discrete Diffusion Models | |
| 肥胖者体内胰岛素对血浆脂质提取及其向肌肉外分流的抑制作用受损 | Katsanos, C. S. | N/A | Impaired Suppression of Plasma Lipid Extraction and its Partitioning Away from Muscle by Insulin in Humans with Obesity | |
| 多步生物合成途径的双重诱导控制系统 | Rincon, A. F. C. | N/A | A dual-inducible control system for multistep biosynthetic pathways | |
| 通过原子分解的突发估计（BEAD）：用于在脑信号中寻找振荡突发的工具箱 | Anand, A. | N/A | Burst Estimation through Atomic Decomposition (BEAD): A Toolbox to find Oscillatory Bursts in Brain Signals | |
| 快速眼动睡眠期间的心率变异性与减少的负面记忆偏差相关 | Morehouse, A. B. | N/A | Heart Rate Variability During Rapid Eye Movement Sleep is Associated with Reduced Negative Memory Bias | |
| 衰老小鼠各组织中的自噬作用 | Carosi, J. M. | N/A | Autophagy across tissues of aging mice | |
| 亲代照料对毒蛙皮肤微生物群落组成的影响 | Fischer, M.-T. | N/A | Effects of parental care on skin microbial community composition in poison frogs | |
| 独立推导预测药物诱发尖端扭转型室性心动过速的异位轴 | Heitmann, S. | N/A | Independent derivations of the axis of arrhythmia for predicting drug-induced torsades de pointes | |
| 人类积极地重构神经任务状态 | Ritz, H. | N/A | Humans actively reconfigure neural task states | |
| 人类积极地重构神经任务状态 | Ritz, H. | N/A | Humans actively reconfigure neural task states | |
| 冷冻电镜展示了驱动蛋白激活途径的多个步骤 | Kendrick, A. | N/A | Cryo-EM visualizes multiple steps of dynein activation pathway | |
| 在运动规划中高效编码 | Wang, T. | N/A | Efficient Coding in Motor Planning | |
| 使用自动编码器生成信号和ResNet分类的脑刺激伪影鲁棒检测 | Saal, J. | N/A | Robust Detection of Brain Stimulation Artifacts in iEEG Using Autoencoder-Generated Signals and ResNet Classification | |
| 通过拓扑高阶功能连接解析精神分裂症中的整合-分离失衡 | Li, Q. | N/A | Unraveling Integration-Segregation Imbalances in Schizophrenia Through Topological High-Order Functional Connectivity | |
| 减少覆盖范围的空间异质性可以提高狗类狂犬病疫苗接种的有效性。 | Ferguson, E. | N/A | Reducing spatial heterogeneity in coverage improves the effectiveness of dog vaccination against rabies | |
| GPR87在肺纤维化中的作用 | Khoury, J. | N/A | The role of GPR87 in Pulmonary Fibrosis | |
| 胞外谷胱甘肽的分解代谢为肿瘤生长提供了氨基酸支持。 | Hecht, F. | N/A | Catabolism of extracellular glutathione supplies amino acids to support tumor growth | |
| 一种结直肠癌中三级淋巴结构数字表征的新方法 | Munoz-Erazo, L. | N/A | A novel approach to digital characterisation of Tertiary Lymphoid Structures in colorectal cancer | |
| 系统挖掘肠道微生物组生物标志物用于炎症性肠病 | Zhang, Y. | N/A | Systematic Mining of gut microbiota biomarkers for IBD | |
| 公开的RNA测序数据并不能代表全球人类的多样性。 | Gallego Romero, I. | N/A | Public RNA-seq data are not representative of global human diversity | |
| 脑部预靶向PET：利用单克隆抗体成像中枢神经系统靶点的新视野 | Gustavsson, T. | N/A | Brain Pretargeted PET; New Horizons to Image CNS Targets with Monoclonal Antibodies | |
| 持续性钠电流将癫痫与Scn8a功能获得性小鼠中的扩散性去极化耦合 | Aiba, I. | N/A | Persistent Na+ current couples seizure with spreading depolarization in Scn8a gain of function mice | |
| 数据驱动的图像分析用于确定抗体诱导的细胞间粘附解离及抗体在寻常型天疱疮中的病原性 | Moghaddam, A. O. | N/A | Data-Driven Image Analysis to Determine Antibody-Induced Dissociation of Cell-Cell Adhesion and Antibody Pathogenicity in Pemphigus Vulgaris | |
| 活跃的RNA合成模式核凝聚物 | Banani, S. F. | N/A | Active RNA synthesis patterns nuclear condensates | |
| 腹侧纹状体与显著网络具有优先关联，包括背外侧前额叶皮层中的区域。 | Kosakowski, H. L. | N/A | Ventral Striatum is Preferentially Correlated with the Salience Network Including Regions in Dorsolateral Prefrontal Cortex | |
| 可可碱和阿糖腺苷的强效抗流感协同作用 | Lahiri, H. | N/A | Potent Anti-Influenza Synergistic Activity of Theobromine and Arainosine | |
| 习惯形成的计算原理 | Lakshminarasimhan, K. J. | N/A | A computational principle of habit formation | |
| DNA聚合酶η受到相互排斥的单泛素化和单NEDD化调控。 | Moreno, N. C. | N/A | DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation | |
| 生物学中的弱磁场效应是可以测量的——在没有地磁场的情况下，爪蟾胚胎发育会加速。 | Lodesani, A. | N/A | Weak magnetic field effects in biology are measurable--accelerated Xenopus embryogenesis in the absence of the geomagnetic field | |
| 从生物物理模型和保存的标本中可靠地重建蟋蟀鸣声 | Weiner, R. J. | N/A | Reliable reconstruction of cricket song from biophysical models and preserved specimens | |
| 从生物物理模型和保存的标本中可靠地重建蟋蟀鸣声 | Weiner, R. J. | N/A | Reliable reconstruction of cricket song from biophysical models and preserved specimens | |
| 直接计算评估粘着斑蛋白-肌动蛋白解离动力学揭示了抓附键行为 | Ccoa, W. J. P. | N/A | A direct computational assessment of vinculin-actin unbinding kinetics reveals catch bonding behavior | |
| 弓形虫引发的侵袭孔 | Kegawa, Y. | N/A | The invasion pore induced by Toxoplasma gondii | |
| 治疗前后肿瘤内遗传异质性模式 | Stein, A. | N/A | On the patterns of genetic intra-tumour heterogeneity before and after treatment | |
| 在光捕获调节下活体衣藻细胞的时间-空间分辨荧光光谱 | Fujita, Y. | N/A | Time- Space Resolved Fluorescence Spectroscopy in Live Chlamydomonas Cells under Light-Harvesting Regulation | |
| ExoSloNano：用于活细胞和冷冻电子断层扫描中大分子识别的多模态纳米金标签 | Young, L. N. | N/A | ExoSloNano: Multi-Modal Nanogold Tags for identi-fication of Macromolecules in Live Cells & Cryo-Electron Tomograms | |
| 数据驱动方程自由动力学应用于多蛋白质复合物：微管尖端松弛 | Wu, J. | N/A | Data-Driven Equation-Free Dynamics Applied to Many-Protein Complexes: The Microtubule Tip Relaxation | |
| 病原性螺旋体中乙酸激酶（AckA）在乙酸生成途径中的作用的生物物理和生化证据 | Deka, R. | N/A | Biophysical and biochemical evidence for the role of acetate kinases (AckAs) in an acetogenic pathway in pathogenic spirochetes | |
| 连接的染色质放大了乙酰化调控的核小体相互作用 | Li, R. | N/A | Connected Chromatin Amplifies Acetylation-modulated Nucleosome Interactions | |
| 用于临床前高场fMRI的非对称自旋回波多回波回波平面成像（ASEME-EPI）序列 | Johnson, K. A. | N/A | Asymmetric spin echo multi-echo echo planar imaging (ASEME-EPI) sequence for pre-clinical high-field fMRI | |
| 艾伦人脑图谱的主题建模分析 | Pizzini, L. | N/A | Topic Modeling analysis of the Allen Human Brain Atlas | |
| 鉴定人类长寿者中IGF-1基因的功能性罕见编码变异 | Ali, A. | N/A | Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity | |
| 序列和结构对RNA中吡咯胞嘧啶荧光的影响 | Coulson, T. L. | N/A | Impacts of sequence and structure on pyrrolocytosine fluorescence in RNA | |
| 特征选择增强了针对TCR特异性相互作用的肽结合预测 | Teimouri, H. | N/A | Feature Selection Enhances Peptide Binding Predictions for TCR-Specific Interactions | |
| HEXIM1同源二聚体结合7SK RNA上的两个位点，以解除对P-TEFb失活的自身抑制作用。 | Yang, Y. | N/A | HEXIM1 homodimer binds two sites on 7SK RNA to release autoinhibition for P-TEFb inactivation | |
| 窦房结细胞中Ryanodine受体簇网络的结构-功能关系 | Maltsev, A. V. | N/A | Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells | |
| 一种不依赖于软件的指标，用于估算单分子在任何定位显微超分辨率实验中的实验定位精度 | Brenlla-Lopez, A. | N/A | A software-independent metric to estimate the experimental localization precision of single molecules in any localization microscopy super-resolution experiment | |
| 整合到丘脑初级和高级抑制性神经元的不同皮层输入 | Puzzo, C. D. | N/A | Integration of distinct cortical inputs to primary and higher order inhibitory cells of the thalamus | |
| 冷冻电子断层扫描揭示了黄病毒复制、出芽和成熟的耦合过程 | Dahmane, S. | N/A | Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation | |
| 新型相关显微技术用于纳米生物界面研究：超细颗粒物诱导肺上皮细胞损伤 | Podlipec, R. | N/A | Novel correlative microscopy approach for nano-bio interface studies of ultrafine particle-induced lung epithelial cell damage | |
| 同种异体脂肪来源的基质细胞能够调节免疫反应，但在C57BL/6小鼠的去细胞化脂肪组织植入物中的持久性有限。 | Walker, J. T. | N/A | Syngeneic adipose-derived stromal cells modulate the immune response but have limited persistence within decellularized adipose tissue implants in C57BL/6 mice | |
| 剖析复杂基因组物种中整个氨基酸转运蛋白家族的营养调控：化弱点为优势的整体方法 | Le Garrec, S. | N/A | Dissecting the nutritional regulations of a whole amino acid transporter family from a complex genome species: A holistic approach turning weaknesses into strengths | |
| 衣被蛋白复合体I对于登革病毒非结构蛋白1的高效分泌是必需的。 | Johnson, S. | N/A | Coatomer protein complex I is required for efficient secretion of dengue virus non-structural protein 1 | |
| 哺乳动物细胞间活体内mRNA运输的证据 | Shubin, A. | N/A | Evidence for in vivo mRNA Transport Between Mammalian Cells | |
| 中性脂质在彗星试验中限制断裂DNA分子的移动性 | Soulet, C. | N/A | Neutral lipids restrict the mobility of broken DNA molecules during comet assays | |
| 神经肽aCGRP损害了软骨细胞对机械负荷的反应。 | Dietmar, H. F. | N/A | The neuropeptide aCGRP impairs the chondrocyte response to mechanical load | |
| 物种特异性卫星DNA组成决定了PRC1介导的着丝粒异染色质的从头形成 | Lamelza, P. | N/A | Species-specific satellite DNA composition dictates de novo formation of PRC1-mediated pericentric heterochromatin | |
| 静息细胞再进入受到巨自噬诱导的溶酶体损伤的限制 | Murley, A. | N/A | Quiescent cell re-entry is limited by macroautophagy-induced lysosomal damage | |
| 通过直接外泌体转染高效地将小RNA递送至体外足细胞。 | Lange, T. | N/A | Efficient delivery of small RNAs to podocytes in vitro by direct exosome transfection. | |
| RNA聚合酶II是前进的DNA复制叉的极性路障。 | Kay, T. M. | N/A | RNA Polymerase II is a Polar Roadblock to a Progressing DNA Fork | |
| 基于mRNA的流感疫苗扩大了人类B细胞反应的广度 | Matz, H. C. | N/A | mRNA-based influenza vaccine expands breadth of B cell response in humans | |
| 高效细胞凋亡诱导：通过生物素或DNA寡聚体结合域修饰的异亮氨酸拉链改性CD95配体的高产纯化 | Shang, X. | N/A | High yield purification of an Isoleucine zipper modified CD95 Ligand with either biotin or DNA-oligomer binding domain for efficient Cell Apoptosis Induction | |
| 通过可逆的YAP介导的细胞周期蛋白D1/p27比率增加引起的短暂增殖 | Ferrick, K. R. | N/A | Transient proliferation by reversible YAP-mediated increase of the cyclin D1/p27 ratio | |
| PDGF-AB/BB对人类椎间盘细胞衰老的保护作用 | Zhang, C. | N/A | Protective effects of PDGF-AB/BB against cellular senescence in human intervertebral disc | |
| miR126介导的Rett综合征中血管完整性受损 | Osaki, T. | N/A | miR126-mediated impaired vascular integrity in Rett syndrome | |
| 加载激活的FGFR和beta1整合素靶向不同的软骨细胞机械应答基因 | Dietmar, H. F. | N/A | Load activated FGFR and beta1 integrins target distinct chondrocyte mechano-response genes | |
| α微管蛋白序列在氨基酸水平上的差异对减数分裂具有独特的要求。 | Chen, L. | N/A | Amino acid-level differences in alpha tubulin sequences are uniquely required for meiosis | |
| 氨基酸通过溶酶体定位增强mTOR激活的协同作用 | Kolaczkowski, O. M. | N/A | Synergistic Role of Amino Acids in Enhancing mTOR Activation Through Lysosome Positioning | |
| 多成分营养补充剂与衰老小鼠的衰老干预具有可比的抗衰老功效 | Brookes, C. | N/A | Comparable anti-ageing efficacies of a multi-ingredient nutraceutical and a senolytic intervention in old mice | |
| 神经相关巨噬细胞调控脂肪稳态贯穿生命周期，并抑制与年龄相关的炎症 | Gonzalez-Hurtado, E. | N/A | Nerve-associated macrophages control adipose homeostasis across lifespan and restrain age-related inflammation | |
| DeepPaint：一个用于细胞成像图像分类的深度学习包 | Luna, D. | N/A | DeepPaint: A deep-learning package for Cell Painting Image Classification | |
| 解码空间组织结构：一种用于多重成像分析的可扩展贝叶斯主题模型 | Peng, X. | N/A | Decoding Spatial Tissue Architecture: A Scalable Bayesian Topic Model for Multiplexed Imaging Analysis | |
| 渗透压调节影响微塑料在淡水和海洋环境中对鱼类的消除作用。 | Pratiwi, H. M. | N/A | Osmoregulation affects elimination of microplastics in fish in freshwater and marine environments | |
| 必需却非不可或缺：肉桂酸4-羟化酶在水稻细胞壁木质化中的作用 | Lam, L. P. Y. | N/A | Essential Yet Dispensable: The Role of CINNAMATE 4-HYDROXYLASE in Rice Cell Wall Lignification | |
| 寄生植物列当（Orobanche cumana Wallr.）对向日葵根细胞的半活体营养感染 | Khablak, S. | N/A | HEMIBIOTROPHIC INFECTION OF SUNFLOWER ROOT CELLS BY THE PARASITE OROBANCHE CUMANA WALLR. | |
| 推断人类睾丸中细胞类型内和细胞类型间的转录后调控 | Khan, S. | N/A | Inferring post-transcriptional regulation within and across cell types in human testis | |
| 自然杀伤细胞介导了静脉注射卡介苗对小鼠肺转移的预防功效。 | Guerrero, C. | N/A | NK cells mediate preventive efficacy of intravenous BCG against lung metastasis in mice | |
| 营养物质添加对疾病的放大作用：从个体到群落水平的机制测试 | Green, E. T. | N/A | Amplification of disease by nutrient addition: Testing mechanisms from individual to community levels | |
| 雄性二型性与出现策略：一种关于Fabriciana nerippe Felder, 1862中雄性先熟的数学模型 | Kubo, H. | N/A | Male Dimorphism and Emergence Strategies: A Mathematical Model of Protandry in Fabriciana nerippe Felder, 1862 | |
| 附口桡足类寄生虫Salmincola markewitschi通过降低宿主摄食活动，减少了幼年鲑科鱼类Salvelinus leucomaenis的体质状况和生长：寄生虫移除实验的证据 | Murakami, L. | N/A | Mouth-attaching copepod Salmincola markewitschi reduces the body condition and growth of juvenile salmonid Salvelinus leucomaenis by decreasing host feeding activity: evidence from parasite removal experiment | |
| 古基因组学揭示了阿塔卡马沙漠早期游牧社会中的驯养骆驼科动物放牧和野生骆驼科动物狩猎活动。 | O'Hare, C. | N/A | Paleogenomics unveil domesticated camelid herding and wild camelid hunting in early pastoralist societies in the Atacama Desert | |
| 来自伊比利亚东部的中世纪基因组揭示了摩里斯科人大规模驱逐在拆除与北非长期存在的遗传桥梁中的作用 | Oteo-Garcia, G. | N/A | Medieval genomes from eastern Iberia illuminate the role of Morisco mass deportations in dismantling a long-standing genetic bridge with North Africa | |
| 通过高分辨率3D染色质相互作用解析心脏疾病GWAS调控非编码位点，揭示与心力衰竭病理生理相关的因果基因 | Gill, R. | N/A | Dissecting Regulatory Non-Coding Heart Disease GWAS Loci with High-Resolution 3D Chromatin Interactions Reveals Causal Genes with Pathophysiological Relevance to Heart Failure | |
| 创伤后骨关节炎的时间依赖性计算模型，用于估计机械炎症机制如何影响软骨聚集蛋白聚糖含量 | Eskelinen, A. S. A. | N/A | Time-dependent computational model of post-traumatic osteoarthritis to estimate how mechanoinflammatory mechanisms impact cartilage aggrecan content | |
| 对25份普通小麦亚基因组间转录组变异的建模揭示了顺式和反式调控结构 | Nomura, Y. | N/A | Modeling of transcriptomic variation among subgenomes in 25 accessions of common wheat reveals cis- and trans-regulation architectures | |
| 可扩展的代谢途径枚举与采样方法，适用于生物体与生态群落 | Oyas, O. | N/A | Scalable enumeration and sampling of minimal metabolic pathways for organisms and communities | |
| MMP21作为一种流体流动传递的形态发生素，在发育过程中赋予生物体左右不对称性。 | Ott, T. | N/A | MMP21 behaves as a fluid flow transported morphogen to impart laterality during development | |
| 最近在黑腹果蝇谱系中出现了密码子偏好的逆转 | Yamashita, H. | N/A | Recent codon preference reversals in the Drosophila melanogaster lineage | |
| 粒细胞集落刺激因子通过依赖I型干扰素的方式，对抗关节炎性阿尔法病毒的发病机制。 | Hameed, M. | N/A | Granulocyte colony-stimulating factor protects against arthritogenic alphavirus pathogenesis in a type I IFN-dependent manner | |
| 冰川消退后，全浮游栉水母Mnemiopsis的快速物种形成 | Ketchum, R. N. | N/A | Rapid speciation in the holopelagic ctenophore Mnemiopsis following glacial recession | |
| 宿主物种对多种病毒易感性的正相关性 | Imrie, R. M. | N/A | Positive correlations in susceptibility to a diverse panel of viruses across host species | |
| 使用AnnDictionary对大型语言模型进行细胞类型注释的基准测试 | Crowley, G. | N/A | Benchmarking Cell Type Annotation by Large Language Models with AnnDictionary | |
| 大型丝氨酸整合酶脱靶发现与深度学习用于全基因组预测 | Bakalar, M. H. | N/A | Large Serine Integrase Off-Target Discovery with Deep Learning for Genome Wide Prediction | |
| 通过基因集嵌入揭示潜在的生物功能关联 | Huang, Y. | N/A | Uncovering Latent Biological Function Associations through Gene Set Embeddings | |
| Argonaute功能的结构和进化决定因素 | Wallmann, A. | N/A | Structural and evolutionary determinants of Argonaute function | |
| 少量错误组装可能会对基于泛基因组的宏基因组分析产生不成比例的影响。 | Majernik, S. N. | N/A | Small amounts of misassembly can have disproportionate effects on pangenome-based metagenomic analyses | |
| Ephrin-A2和磷酸抗原介导的γδT细胞选择性杀伤髓母细胞瘤，同时保留神经元和干细胞的完整性 | Boutin, L. | N/A | Ephrin-A2 and Phosphoantigen-Mediated Selective Killing of Medulloblastoma by γδT Cells Preserves Neuronal and Stem Cell Integrity | |
| 探索通过合成生物学生产的异贝壳杉烯酸的药理潜力 | Pimentel, L. L. | N/A | Exploring the Pharmacological Potential of Kaurenoic Acid Produced via Synthetic Biology | |
| 从萝芙木中鉴定潜在的多巴胺受体D2拮抗剂：一种基于计算机的虚拟筛选方法 | Chakraborty, S. | N/A | Identifying potential dopamine receptor D2 antagonist from Rauwolfia serpentina An in-silico virtual screening approach | |
| 两种亚麻品种的比较分析表明，木脂素介导的盐胁迫适应性 | Debnath, A. J. | N/A | A comparative analysis between two flax varieties indicates lignan-mediated salt stress adaptiveness | |
| 过去100年间小麦根系水力特性的演变 | Baca Cabrera, J. C. | N/A | The evolution of root hydraulic traits in wheat over 100 years of breeding | |
| 甲基对羟基苯甲酸酯抑制果蝇病原菌铜绿假单胞菌的毒力和传播能力 | Henry, Y. | N/A | Methylparaben dampens virulence and transmissibility of the Drosophila pathogen Pseudomonas entomophila | |
| 单细胞转录组分析揭示了肥胖相关免疫细胞动力学在阿尔法病毒感染期间的变化 | Hameed, M. | N/A | Obesity-Associated Changes in Immune Cell Dynamics During Alphavirus Infection Revealed by Single Cell Transcriptomic Analysis | |
| 直接和间接的RANK配体及CD40配体信号调控成年胸腺中胸腺上皮细胞频率和特性的维持 | Hayama, M. | N/A | Direct and indirect RANK ligand and CD40 ligand signaling regulate the maintenance of thymic epithelial cell frequency and properties in the adult thymus | |
| 转录因子PU.1的抑制通过CXCL9-CXCR3轴促进细胞毒性淋巴细胞的招募，从而抑制小鼠肿瘤生长。 | Sleapnicov, N. | N/A | Inhibition of the transcription factor PU.1 suppresses tumor growth in mice by promoting the recruitment of cytotoxic lymphocytes through the CXCL9-CXCR3 axis | |
| 细胞酶和表没食子儿茶素-3-没食子酸酯作为抗生素疗效增强剂在多微生物生物膜治疗中的研究 | Murray, O. | N/A | An Investigation of Cellulase and Epigallocatechin-3-gallate as Enhancers of Antibiotic Efficacy in Polymicrobial Biofilm Treatments | |
| 非经典糖蛋白H复合物增强巨细胞病毒进入 | Norris, M. J. | N/A | A noncanonical glycoprotein H complex enhances cytomegalovirus entry | |
| SUMO化以一种基因组上下文特异性的方式，差异性地调控SMCHD1复合体的形成及其功能 | Goossens, R. | N/A | SUMOylation differentially regulates SMCHD1 complex formation and function in a genomic context-specific manner | |
| 一类类似于Tn7的转座子家族进化出了针对CRISPR重复序列的能力。 | Chacon Machado, L. | N/A | A family of Tn7-like transposons evolved to target CRISPR repeats | |
| 启动子和增强子依赖的凝聚蛋白加载启动染色体环化，以折叠Tcrb位点进行长程重组 | Bassing, C. | N/A | Promoter- and Enhancer-Dependent Cohesin Loading Initiates Chromosome Looping to Fold Tcrb Loci for Long-Range Recombination | |
| 从雄性骨骼肌中分离出的线粒体含有一组独特的miRNA，这些miRNA在急性运动后表现出差异表达。 | Silver, J. | N/A | Mitochondria isolated from male skeletal muscle contain a distinct 1 population of miRNA that are differentially expressed following acute exercise | |
| 急性与慢性农药暴露在熊蜂大脑中引发根本不同的分子反应 | Witwicka, A. | N/A | Acute and chronic pesticide exposure trigger fundamentally different molecular responses in bumble bee brains | |
| 自然浮游生物群落中的生物多样性预测揭示了温度和生物相互作用作为关键预测因素 | Merz, E. | N/A | Biodiversity forecasting in natural plankton communities reveals temperature and biotic interactions as key predictors | |
| 比较单细胞分析揭示了蝙蝠翅膀发育中保守基因程序的进化再利用 | Schindler, M. | N/A | Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene program in bat wing development | |
| 人口基因组学揭示了在没有清除的情况下遗传漂移的强烈影响，并指导了巨藻和巨藻的保护 | Bemmels, J. B. | N/A | Population genomics reveals strong impacts of genetic drift without purging and guides conservation of bull and giant kelp | |
| 人类大脑转录组中性别偏好的早期确立与生命历程稳定性 | Benoit-Pilven, C. | N/A | Early establishment and life course stability of sex biases in the human brain transcriptome | |
| 在多发性骨髓瘤患者中，基因表达和预后结果受到生殖系和体细胞遗传效应的影响。 | Natri, H. M. | N/A | Germline and somatic genetic effects on gene expression and outcome in patients with Multiple Myeloma | |
| 利用自适应采样对儿童急性白血病进行实时基因组特征分析 | Geyer, J. | N/A | Real-time genomic characterization of pediatric acute leukemia using adaptive sampling | |
| 哺乳动物基因组中独特区域的检测与注释 | Vieira Mourato, B. | N/A | Detection and Annotation of Unique Regions in Mammalian Genomes | |
| 泛基因组揭示了基因内容变异和结构变异对猪特征的影响 | Du, H. | N/A | Pangenome Reveals Gene Content Variations and Structural Variants Contributing to Pig Characteristics | |
| 高分辨率全基因组染色质可及性和扭转应力图谱分析 | Hall, P. M. | N/A | High-Resolution Genome-Wide Mapping of Chromatin Accessibility and Torsional Stress | |
| 一套基础模型捕捉到了密码子之间的上下文相互作用 | Naghipourfar, M. | N/A | A Suite of Foundation Models Captures the Contextual Interplay Between Codons | |
| 保留隐藏的层次结构：用于增强基因组序列分析的庞加莱距离 | Ali, S. | N/A | Preserving Hidden Hierarchical Structure: Poincare Distance for Enhanced Genomic Sequence Analysis | |
| 一种从烟草（Nicotiana benthamiana）中纯化用于结构研究的重组蛋白的多功能协议 | Lawson, A. W. | N/A | A versatile protocol for purifying recombinant proteins from Nicotiana benthamiana for structural studies | |
| 在非人灵长类动物肝脏中通过可编程基因组整合实现了内源基因替换的治疗水平 | Xie, J. | N/A | Curative levels of endogenous gene replacement achieved in non-human primate liver using programmable genomic integration | |
| 探究深度图神经网络在RNA二级结构预测中的效率 | Saon, M. S. | N/A | Exploring the Efficiency of Deep Graph Neural Networks for RNA Secondary Structure Prediction | |
| 评估序列和结构相似性指标以预测共享旁系同源功能 | Dennler, O. | N/A | Evaluating Sequence and Structural Similarity Metrics for Predicting Shared Paralog Functions | |
| 模式识别受体FLS2的逆向工程揭示了更广泛识别逃避flg22表位的关键设计原则 | Zhang, S. | N/A | Reverse engineering of the pattern recognition receptor FLS2 reveals key design principles of broader recognition spectra against evading flg22 epitopes | |
| 无细胞生物传感器的半自动化生产 | Brown, D. M. | N/A | Semi-automated Production of Cell-free Biosensors | |
| 杏仁核中适应性价值编码的神经机制 | Hinz, J. | N/A | Neural mechanisms of adaptive value coding in the amygdala | |
| 淀粉样β蛋白、α-突触核蛋白和tau蛋白的共病理聚集加剧了神经病理学和神经炎症 | Webster, J. M. | N/A | Amyloid-beta, alpha-synuclein and tau aggregated co-pathologies enhance neuropathology and neuroinflammation | |
| 我们能否根据大脑特征预测睡眠健康？一项大规模机器学习研究 | Raimondo, F. | N/A | Can we predict sleep health based on brain features? A large-scale machine learning study | |
| 通过首次通过分析追踪神经元树突的形态演变 | Kreten, F. | N/A | Tracking the Morphological Evolution of Neuronal Dendrites by First-Passage Analysis | |
| 一个详细的生物物理学模型，描述了皮层感觉处理中区域间相互作用的情况。 | Bolanos-Puchet, S. | N/A | A biophysically-detailed model of inter-areal interactions in cortical sensory processing | |
| X射线衍射揭示了小鼠新皮质中的周期性结构 | Murokh, S. | N/A | X-ray Diffraction Reveals Periodicity in Murine Neocortex | |
| 体外活性：羟氯喹与抗生素联合作用对胞内尿路致病性大肠杆菌的效果 | Pargny, V. | N/A | In vitro activity of hydroxychloroquine in combination with antibiotics against intracellular uropathogenic Escherichia coli | |
| 表面活性素加速枯草芽孢杆菌菌膜生物膜的形成 | Stannius, R. O. | N/A | Surfactin accelerates Bacillus subtilis pellicle biofilm development | |
| 尽管CpG水平升高，HIV-2仍进化出了对ZAP的抗性。 | Kmiec, D. | N/A | HIV-2 evolved ZAP resistance despite increased CpG levels | |
| 食品级细菌瑞士乳杆菌VEL12193通过释放膜泡促进自噬。 | Bringer, M.-A. | N/A | The food grade bacterium Lactobacillus helveticus VEL12193 promotes autophagy by releasing membrane vesicles | |
| 具有特殊形态的花朵会产生更多的花蜜和花粉吗？ | Keasar, T. | N/A | Do flowers with specialized morphologies produce more nectar and pollen? | |
| 悬浮和沉降颗粒相关微生物群在易北河河口展现出不同的生活方式 | Tobias-Hünefeldt, S. P. | N/A | Suspended and sinking particle-associated microbiomesexhibit distinct lifestyles in the Elbe estuary | |
| NAD的二核苷酸结构使其能够在矿物表面上进行特定的还原作用。 | Pereira, D. P. H. | N/A | The dinucleotide structure of NAD enables specific reduction on mineral surfaces | |
| 利用新型基因组资源和统计方法结合个体和池化测序数据，对过去和未来斑翅果蝇（Drosophila suzukii）入侵的新见解 | Camus, L. | N/A | New insights into past and future invasion of Drosophila suzukii using novel genomic resources and statistical methods to combine individual and pool sequencing data | |
| 利用全基因组关联作图鉴定硬粒冬小麦中的叶锈病抗性位点 | Lakkakula, I. P. | N/A | Identification of leaf rust resistance loci in hard winter wheat using genome-wide association mapping | |
| 一种用于菱形蛋白酶RHBDL4酶学特性研究的体外平台 | Bhaduri, S. E. | N/A | An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4 | |
| 通过计算蛋白质工程改进Split-HaloTag | Wilhelm, J. | N/A | Improving Split-HaloTag through Computational Protein Engineering | |
| 基于噬菌体微流控的PDMS表面定向固定SpyTag噬菌体的研究 | Liyanagedera, S. B. W. | N/A | Directional Immobilisation of SpyTag Bacteriophage on PDMS surfaces for Phage based Microfluidics | |
| 利用基础语言模型解读RNA调控 | Zhou, H. | N/A | Deciphering RNA regulation with a foundation language model | |
| 高血压中肠道微生物代谢通路紊乱的机制 | Wenkai, L. | N/A | Mechanism of intestinal microbial metabolic flux disorder in hypertension | |
| 猪繁殖与呼吸综合征病毒和猪流感A病毒感染对呼吸道淋巴结B细胞和巨噬细胞影响的比较研究。 | Hervet, C. | N/A | Comparative impact of porcine reproductive and respiratory virus and swine influenza A virus infections on respiratory lymph nodes B cells and macrophages. | |
| 适应过程中适应性效应分布的动态变化 | Morales, D. T. | N/A | Dynamics of the distribution of fitness effects during adaptation | |
| 甲虫-真菌互利共生中共生真菌的基因组多样化 | Huang, Y.-T. | N/A | Genome diversification of symbiotic fungi in beetle-fungus mutualistic symbiosis | |
| 塑造微小世界：父系微生物群操控影响后代微生物定植与发育——以性别角色反转的管海马为例 | Wagner, K.-S. | N/A | Shaping tiny worlds: Paternal microbiota manipulation influences offspring microbial colonization and development in a sex role-reversed pipefish | |
| DNA甲基化时钟在区分炎症性衰老与健康衰老方面存在困难，但特征修正能提高一致性并增强对炎症性衰老的检测能力。 | Skinner, C. M. | N/A | DNA methylation clocks struggle to distinguish inflammaging from healthy aging, but feature rectification improves coherence and enhances detection of inflammaging | |
| UniScore，一种通过多重搜索引擎进行肽段鉴定的统一且通用的评估标准 | Tabata, T. | N/A | UniScore, a unified and universal measure for peptide identification by multiple search engines | |
| DeepAllo：利用蛋白质语言模型（pLM）结合多任务学习进行变构位点预测 | Khokhar, M. | N/A | DeepAllo: Allosteric Site Prediction using Protein Language Model (pLM) with Multitask Learning | |
| RNA测序深度指南，用于研究可变剪接 | Tsoy, O. | N/A | RNA sequencing depth guidelines for the study of alternative splicing | |
| NKX2-2独立调控神经发生和背腹模式形成 | Jang, S. | N/A | Independent control of neurogenesis and dorsoventral patterning by NKX2-2 | |
| 量化相对海绵性：作为生态系统服务的高分辨率景观水保持模型 | Evans, P. M. | N/A | Quantifying relative sponginess: a high-resolution model of landscape water retention as an ecosystem service | |
| 受开发影响的湖泊中冰物候变化产生的连锁后果 | Goto, D. | N/A | Cascading consequences of shifting ice phenology in an exploited lake | |
| # BioRxiv 2024-10-12 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 催乳素和DNA损伤会引发抗乳腺癌细胞的免疫反应。 | Karayazi Atici, O. | N/A | Prolactin and DNA damage trigger an anti-breast cancer cellimmune response | |
| 启动子近端暂停的进化实现了一层新的转录调控 | Chivu, A. G. | N/A | Evolution of promoter-proximal pausing enabled a new layer of transcription control | |
| 北极猛禽的狐步迁徙及动态越冬范围 | Pokrovsky, I. | N/A | Foxtrot migration and dynamic over-wintering range of an arctic raptor | |
| 利用光遗传学控制RhoA的GEF揭示了从收缩到突起的信号开关 | de Seze, J. | N/A | Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion | |
| 小鼠眶额皮层中信息内在价值的表征 | Bussell, J. J. | N/A | Representations of the intrinsic value of information in mouse orbitofrontal cortex | |
| 蚊子发育过程中细菌代谢物的营养性别特异性导致成虫性别比例失衡 | Romoli, O. | N/A | Nutritional sex-specificity on bacterial metabolites during mosquito development leads to adult sex-ratio distortion | |
| 经过验证的触摸视频数据库 | Smit, S. | N/A | The validated touch-video database | |
| 重新思考休眠：抗生素持久者是具有代谢活性、非生长的细胞 | Rahman, K. M. T. | N/A | Rethinking Dormancy: Antibiotic Persisters are Metabolically Active, Non-Growing Cells | |
| 尼古丁通过Hippo-YAP/TAZ和Notch信号通路增强肠干细胞的干性和肿瘤发生能力。 | Isotani, R. | N/A | Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway | |
| 有效连接预测感知决策信心、不确定性和速度的分布式神经编码 | Asadpour, A. | N/A | Effective connectivity predicts distributed neural coding of perceptual decision confidence, uncertainty and speed | |
| 描述早产儿和足月婴儿在睡眠期间脑活动的时间动态和成熟特征：一项基于EEG微状态的研究。 | Adibpour, P. | N/A | Characterizing the temporal dynamics and maturation of brain activity during sleep: an EEG microstate study in preterm and full-term infants. | |
| SERBP1与PARP1相互作用，并存在于依赖于PARylation的蛋白质复合物中，这些复合物调控剪接、细胞分裂和核糖体生物发生。 | Breunig, K. | N/A | SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis | |
| 在运动神经元退化的鼠模型中，脊髓微循环经历了多相的稳态补偿。 | Nascimento, F. | N/A | Spinal microcircuits go through multiphasic homeostatic compensations in a mouse model of motoneuron degeneration | |
| 与怀疑者相比，超自然信仰者在联合视觉搜索中更快但更不准确地拒绝目标的存在。 | Akbari, F. | N/A | Paranormal believers are quicker but less accurate in rejecting the presence of the target in conjunction visual search compared to skeptics | |
| TRMT1L催化的酪氨酸tRNA上的m22G27对于在氧化应激下实现高效的mRNA翻译和细胞存活是必需的。 | Hwang, S.-P. | N/A | TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress. | |
| 全基因组关联分析生长速率在波动和极端温度下的变化 | Räsänen, E. | N/A | Genome-wide association mapping for growth rate at fluctuating and extreme temperatures | |
| 有丝分裂期间PI(3,5)P2的不对称性对于不对称液泡遗传至关重要 | Huda, M. | N/A | PI(3,5)P2 asymmetry during mitosis is essential for asymmetric vacuolar inheritance | |
| 从蛋白质序列信息设计不同长度的线性和环状肽结合剂 | Li, Q. | N/A | Design of linear and cyclic peptide binders of different lengths from protein sequence information | |
| 使用Gibbs采样和edgeR v4进行更快更准确的差异转录表达评估 | Baldoni, P. L. | N/A | Faster and more accurate assessment of differential transcript expression with Gibbs sampling and edgeR v4 | |
| Dclk1基因表达的调控网络分析揭示了一个簇细胞-ILC2轴，该轴抑制胰腺肿瘤进展。 | Valenti, G. | N/A | Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression | |
| 一罐蠕虫：估算全球蚯蚓物种数量 | Decaens, T. | N/A | A can of worms: estimating the global number of earthworm species | |
| 与糖尿病和糖尿病肾病相关的尿液微生物群：系统综述 | Graells, T. | N/A | The urinary microbiome in association with diabetes and diabetic kidney disease: A systematic review | |
| 核孔蛋白Nup153将剪接机制锚定在核孔上，以实现高效的mRNA加工 | De Castro, I. | N/A | Nucleoporin Nup153 docks the splicing machinery to the nuclear pore for efficient mRNA processing | |
| 与满江红（Azolla filiculoides）共培养的水稻植株改变了根系结构和发育阶段的时机 | Cannavo', S. | N/A | Co-cultivating rice plants with Azolla filiculoides modifies root architecture and timing of developmental stages | |
| 自上而下的反馈至关重要：类脑连接模式对视听整合的功能影响 | Tugsbayar, M. | N/A | Top-down feedback matters: Functional impact of brainlike connectivity motifs on audiovisual integration | |
| 海马长轴功能特化受成年寿命影响 | Bowman, C. | N/A | Adult lifespan effects on functional specialization along the hippocampal long axis | |
| 开发具有广泛治疗潜力的临床可行非肌肉肌球蛋白II小分子抑制剂 | Radnai, L. | N/A | Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential | |
| 在肝硬化肝脏中进行纯化的梭菌胶原酶间质输注可迅速减少纤维化，且肝毒性最小。 | Leaker, B. D. | N/A | Interstitial infusion of purified collagenase Clostridium histolyticum in the cirrhotic liver causes rapid reduction in fibrosis with minimal liver toxicity | |
| 货物适配器身份控制动力蛋白激活的机制和动力学 | Gillies, J. P. | N/A | Cargo adaptor identity controls the mechanism and kinetics of dynein activation | |
| 胰岛素抵抗性肥胖中的血浆外泌体加剧三阴性乳腺癌的进展 | Llevenes, P. | N/A | Plasma Exosomes in Insulin Resistant Obesity Exacerbate Progression of Triple Negative Breast Cancer | |
| 阿波罗：一种综合性的基于GPU的主机内模拟器，用于模拟病毒进化和感染动力学，涵盖群体、组织和细胞层面。 | Perera, D. | N/A | Apollo: A comprehensive GPU-powered within-host simulator for viral evolution and infection dynamics across population, tissue, and cell | |
| 口服避孕药对大脑网络的影响：一项重复和扩展研究 | Haase, G. | N/A | Effects of oral contraceptive pills on brain networks: A replication and extension | |
| 基准测试用于抗体设计的生成模型 | Ucar, T. | N/A | Benchmarking Generative Models for Antibody Design | |
| 食物纳米材料引起的肠道屏障破坏的不良结局路径。 | Stanco, D. | N/A | An Adverse Outcome Pathway for Food Nanomaterial-induced Intestinal Barrier Disruption. | |
| 沉浸于自然环境可减弱机械性继发性痛觉过敏的发展：岛叶-丘脑有效连接的作用 | Medina, S. | N/A | Immersion in nature attenuates the development of mechanical secondary hyperalgesia: a role for insulo-thalamic effective connectivity | |
| 结直肠癌淋巴结转移相关肠道菌群的鉴定及预测机器学习模型构建 | Wu, Y. | N/A | Identification and predictive machine learning models construction of gut microbiota associated with lymph node metastasis in colorectal cancer | |
| 循环微小RNA作为慢性肾脏病及其与非透析患者肾脏和心血管结局关联的生物标志物 | Ramil - Gomez, O. | N/A | Circulating microRNAs as biomarkers of chronic kidney disease and its association with renal and cardiovascular outcomes in non-dialysis patients | |
| 利用已知的出生情况来解释北冰洋露脊鲸种群估计中的标记延迟 | Linden, D. W. | N/A | Using known births to account for delayed marking in population estimation of North Atlantic right whales | |
| “混合群”的模糊性：现有研究中定义和应用的不一致性 | Campbell, J. N. | N/A | The ambiguity of "hybrid swarm": inconsistent definitions and applications in existing research | |
| 人口结构限制了从森林树木的基因组预测和全基因组关联研究中得出的推论。 | Slavov, G. T. | N/A | Population structure limits inferences from genomic prediction and genome-wide association studies in a forest tree | |
| 构建用于采集小肠内容物样本的胶囊的逐步方法 | Ollagnier, C. | N/A | Step-by-step methodology for building a capsule to sample small intestine content | |
| 去伪存真：结构MRI图像质量评估中的偏差 | Provins, c. | N/A | Defacing biases visual quality assessments of structural MRI | |
| 单细胞ATAC-seq数据的多模态整合能够高度准确地描绘出临床相关的肿瘤细胞亚群。 | Xiong, K. | N/A | Multimodal integration of single cell ATAC-seq data enables highly accurate delineation of clinically relevant tumor cell subpopulations | |
| 系统挖掘肠道微生物组生物标志物用于炎症性肠病 | Yuchen, Z. | N/A | Systematic Mining of gut microbiota biomarkers for IBD | |
| 已发表的兔核糖体rRNA序列中的不一致性：关于序列和位点编号统一性的建议 | De, S. | N/A | Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering | |
| 利用肿瘤-免疫动力学综合模型预测慢性髓性白血病患者的无治疗缓解结果 | Fassoni, A. C. | N/A | Predicting treatment-free remission outcomes in Chronic Myeloid Leukemia patients using an integrated model of tumor-immune dynamics | |
| 结构和功能证据支持将小鼠的高级视觉区域重新定义为单一的V2区域。 | Rowley, D. P. | N/A | Structural and functional evidence supports re-defining mouse higher order visual areas into a single area V2 | |
| 纤维肌痛患者存在与疾病症状严重程度和抗卫星胶质细胞IgG抗体相关的脂质浓度改变。 | Jakobsson, J. E. | N/A | Fibromyalgia patients have altered lipid concentrations associated with disease symptom severity and anti-satellite glial cell IgG antibodies | |
| 焦虑/抑郁个体在认知冲突编码过程中表现出前额叶-颞叶同步性紊乱 | Shekara, A. | N/A | Anxious/depressed individuals exhibit disrupted frontotemporal synchrony during cognitive conflict encoding | |
| 皮层阿尔法节律从自然场景背景中插值被遮挡的运动 | Yeh, L.-C. | N/A | Cortical alpha rhythms interpolate occluded motion from natural scene context | |
| AB5枯草杆菌溶素细胞毒素诱导的ISR通过STING激活驱动pDCs中IFN-I的表达 | Pierre, P. | N/A | Induction of the ISR by AB5 subtilase cytotoxin drives IFN-I expression in pDCs via STING activation | |
| HighALPS：在Illumina NextSeq和NovaSeq平台上进行超高通量标记基因扩增子文库制备与测序 | Flörl, L. | N/A | HighALPS: Ultra-High-Throughput Marker-Gene Amplicon Library Preparation and Sequencing on the Illumina NextSeq and NovaSeq Platforms | |
| 利用遗传和表观遗传筛选方法，将候选因果自身免疫变异与人类原代T细胞网络相联系。 | Ho, C.-H. | N/A | Linking candidate causal autoimmune variants to T cell networks using genetic and epigenetic screens in primary human T cells. | |
| 禾草等长穗（Alopecurus aequalis）的染色体规模基因组组装与从头注释。 | Wright, J. | N/A | Chromosome-scale genome assembly and de novo annotation of Alopecurus aequalis. | |
| 三叶草复合体中重复的靶心图案减少的遗传基础 | Yeo, M. T. S. | N/A | The genetic basis of replicated bullseye pattern reduction across the Trionum Complex | |
| 性别特异性：体力活动强度和剂量对BOLD-fMRI脑血管反应性和脑脉动性的影响 | Potvin-Jutras, Z. | N/A | Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility | |
| 高分辨率的黑色素皮质素-4受体深度突变扫描为药物发现提供了目标特征 | Howard, C. J. | N/A | High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery | |
| 利用基于成像的分子记录技术重构单细胞信号传导历史 | Hao, K. | N/A | Reconstructing signaling history of single cells with imaging-based molecular recording | |
| 生物分子自适应控制器设计以恢复持续的周期性行为 | Britto Bisso, F. | N/A | Design of a biomolecular adaptive controller to restore sustained periodic behavior | |
| 基础成纤维细胞生长因子有助于保护面部神经细胞在冷冻诱导的瘫痪模型中 | Iwata, S. | N/A | Basic fibroblast growth factor helps protect facial nerve cells in a freeze-induced paralysis model | |
| 猕猴和人胎盘类器官的比较分析突显了胎盘形成中的进化差异 | Caldwell, A. | N/A | Comparative analysis of rhesus macaque and human placental organoids highlights evolutionary differences in placentation | |
| 通过锌指抑制因子驱动的表观遗传沉默，增强CAR-T细胞和TILs中免疫检查点和TGFBR2的抗肿瘤活性 | David, M. | N/A | Enhanced anti-tumor activity by Zinc Finger Repressor-driven epigenetic silencing of immune checkpoints and TGFBR2 in CAR-T cells and TILs | |
| TGFβ1-TNFα调控的中性粒细胞趋化因子分泌与乳腺癌细胞的上皮-间质转化无关 | Sengupta, S. | N/A | TGFβ1-TNFα regulated secretion of neutrophil chemokines is independent of epithelial-mesenchymal transitions in breast tumor cells | |
| 绘制乳腺癌的时间景观：利用表观遗传熵 | Monyak, D. L. | N/A | Mapping the Temporal Landscape of Breast Cancer Using Epigenetic Entropy | |
| 精选癌症细胞图谱：全面解析肿瘤在单细胞分辨率下的特征 | Tyler, M. | N/A | The Curated Cancer Cell Atlas: comprehensive characterisation of tumours at single-cell resolution | |
| 干龟国家公园石珊瑚种类的代谢组学特征显示出种间和种内变异。 | Deutsch, J. M. | N/A | Metabolomic profiles of stony coral species from the Dry Tortugas National Park display inter- and intraspecies variation | |
| 饲喂水葫芦（Eichhornia crassipes）饲料，无论是否添加商业浓缩物，对热带山羊和绵羊的动物技术性能及盈利能力的影响 | Fanta, Y. U. | N/A | Effects of feeding water hyacinth (Eichhornia crassipes) fodder with or without commercial concentrate on zoo-technical performance and profitability in tropical goats and sheep | |
| 通过体外功能细胞集合体绘制突触集合体 | Zaccaria, C. | N/A | Mapping Synaptic Ensembles Through In Vitro Functional Cell Assemblies | |
| 噪声中神经语音追踪的SNR、语音可懂度和注意力努力的不同作用 | He, X. | N/A | Distinct roles of SNR, speech Intelligibility, and attentional effort on neural speech tracking in noise | |
| 多丝氨酸肽具有毒性，并会加剧小鼠中的tau病理变化。 | Van Alstyne, M. | N/A | Polyserine peptides are toxic and exacerbate tau pathology in mice | |
| 三维定量微弹性成像揭示了小鼠卵巢在衰老过程中卵泡和黄体的空间弹性模式的变化。 | Jaeschke, A. | N/A | Three-dimensional quantitative micro-elastography reveals alterations in spatial elasticity patterns of follicles and corpora lutea in murine ovaries during ageing | |
| 一种新烟碱类杀虫剂导致熊蜂组织特异性基因表达变化 | Witwicka, A. | N/A | A neonicotinoid pesticide causes tissue-specific gene expression changes in bumble bees | |
| 神秘浇水壶贝的基因组揭示了活体吸盘锚的适应性 | Sigwart, J. | N/A | Genome of the enigmatic watering-pot shell reveals adaptations of a living suction anchor | |
| ReAct项目：分析来自23个不同实验室的数据，以表征在两组活动水平命题下的DNA恢复情况 | Gill, P. | N/A | The ReAct project: Analysis of data from 23 differentlaboratories to characterise DNA recovery given twosets of activity level propositions | |
| 一种保守转录因子结合位点图谱揭示了开花植物的细胞类型解析基因调控景观 | Baumgart, L. A. | N/A | An atlas of conserved transcription factor binding sites reveals the cell type-resolved gene regulatory landscape of flowering plants | |
| 公开的RNA-seq数据并不能全面代表全球人类的多样性。 | Gallego Romero, I. | N/A | Public RNA-seq data are not representative of global human diversity | |
| 耐热的阿拉伯鳉鱼（Aphanius dispar）作为一种新型感染模型，用于研究人类真菌病原体 | Minhas, R. | N/A | The thermotolerant Arabian killifish, Aphanius dispar, as a novel infection model for human fungal pathogens | |
| 蜜蜂飞行中的群体协调依赖于成对相互作用、反馈规则变化以及深思熟虑的决策。 | Faruque, I. | N/A | Pairwise interactions, feedback rule changes, and deliberative decisions underlie honeybee inflight group coordination | |
| 小鼠皮质卒中后的比例恢复 | Kalantari, A. | N/A | Proportional recovery in mice with cortical stroke | |
| 繁殖经历促使雄性加州田鼠（Peromyscus californicus）在行为和生理上发生改变。 | Colt, M. E. | N/A | Reproductive experience drives changes in behavior and physiology in male California mice (Peromyscus californicus) | |
| 利用深度学习设计新型PHA合成酶 | Tenkanen, T. | N/A | New-to-nature PHA synthase design using deep learning | |
| 非侵入式脑机接口控制与人工智能副驾驶 | Lee, J. Y. | N/A | Non-invasive brain-machine interface control with artificial intelligence copilots | |
| 一款全面的应用程序，用于解读和可视化KEGG通路和基因本体论的功能分析 | Mena, A. R. | N/A | A Comprehensive App to Interpret and Visualize the Functional Analysis of KEGG Pathways and Gene Ontologies | |
| DigestR是一款开源软件工具，用于可视化由天然蛋白质分解产生的LC-MS蛋白质组学数据。 | de Lamache, D. D. | N/A | DigestR an open-source software tool for visualizing LC-MS proteomics data resulting from natural protein catabolism | |
| vScreenML v2.0：改进的基于结构的虚拟筛选中减少假阳性的人工智能分类技术 | Andrianov, G. V. | N/A | vScreenML v2.0: Improved Machine Learning Classification for Reducing False Positives in Structure-Based Virtual Screening | |
| PROPERMAB：一种利用机器学习进行抗体可开发性计算机预测的综合框架 | Li, B. | N/A | PROPERMAB: an integrative framework for in silico prediction of antibody developability using machine learning | |
| 物种丰富度估算的综合评述与评价 | Schmitz, J. E. | N/A | A Comprehensive Review and Evaluation of Species Richness Estimation | |
| 聚合物模型结合超分辨率成像和表观基因组测序，阐明表观遗传反应在塑造四维染色质组织中的作用 | Vinayak, V. | N/A | Polymer Model Integrates Super-Resolution Imaging and Epigenomic Sequencing to Elucidate the Role of Epigenetic Reactions in Shaping 4D Chromatin Organization | |
| 鲁索利替尼通过泛素-蛋白酶体系统清除CRYAB p.Arg120Gly聚集物 | Alizoti, E. | N/A | Ruxolitinib clears CRYAB p.Arg120Gly aggregates through the ubiquitin-proteasome system | |
| 代谢精细调节和心脏细胞因子分泌是果蝇对高脂肪和高糖饮食的适应性反应。 | Khamvongsa-Charbonnier, L. | N/A | Metabolism fine tuning and cardiokines secretion represent adaptative responses of the heart to High Fat and High Sugar Diets in flies | |
| 一种新的肌肉收缩离体模型，用于测量肌肉内分泌和旁分泌信号传导 | DABADIE, C. | N/A | A novel ex vivo model of muscle contraction to measure muscle endocrine and paracrine signalling | |
| 通过神经元受体进行细菌感应，启动肠道线粒体监测以适应宿主 | Liu, H. | N/A | Bacterial sensing via Neuronal Receptor Initiates Gut Mitochondrial Surveillance for Host Adaptation | |
| 经颅超声皮质电路刺激的微观解构 | Lemaire, T. | N/A | Microscopic deconstruction of cortical circuit stimulation by transcranial ultrasound | |
| 在感染SIV的恒河猴中，大麻素使基底神经节的miRNA m6A甲基化谱向抗炎表型转变。 | Okeoma, C. M. | N/A | Cannabinoids shift the basal ganglia miRNA m6A methylation profile towards an anti-inflammatory phenotype in SIV-infected Rhesus macaques | |
| 纹状体伏隔核通路通过一个厌恶性的Esr1+下丘脑-缰核回路驱动强迫性寻求行为。 | Contesse, T. | N/A | A striosomal accumbens pathway drives compulsive seeking behaviors through an aversive Esr1+ hypothalamic-habenula circuit. | |
| 小血管脑病遗传决定因子TRIM47通过NRF2抗氧化系统调控脑稳态 | Duplaa, C. | N/A | Cerebral Small Vessel Disease genetic determinant TRIM47 controls brain homeostasis via the NRF2 antioxidant system | |
| 结合计算流体动力学建模和几何形态计量学方法，量化从光片荧光显微镜成像重建的胚胎鸡心脏解剖结构的血流动力学和解剖特征 | Giesbrecht, K. | N/A | A Combined Computational Fluid Dynamics Modeling and Geometric Morphometrics Methods Approach to Quantifying Hemodynamic and Anatomical Features of Embryonic Chick Heart Anatomies Reconstructed from Light Sheet Fluorescence Microscopy Imaging | |
| 从木本被子植物的木质部特异性肽前体中衍生出的进化保守的树液肽 | Chen, C.-H. | N/A | Evolutionary conserved sap peptides derived from xylem-specific peptide precursors in woody angiosperms | |
| 单细胞整合揭示了炎症性肠病中的化生现象 | Oliver, A. J. | N/A | Single Cell Integration Characterises Metaplasia in Inflammatory Intestinal Diseases | |
| 动态屏障调节着粘连蛋白定位和固定占用率下的基因组折叠 | Rahmaninejad, H. | N/A | Dynamic barriers modulate cohesin positioning and genome folding at fixed occupancy | |
| 利用高斯过程估计重建的多带成像加速多壳扩散磁共振成像 | Ye, X. | N/A | Accelerated multi-shell diffusion MRI with Gaussian process estimated reconstruction of multi-band imaging | |
| 通过磁遗传学工具调控人类T淋巴细胞 | Helalat, S. H. | N/A | Regulating Human T Lymphocytes Through Magnetogenetic Tools | |
| 模拟揭示了着陆运动学变量如何影响最高短跑速度：对教练的启示 | Haralabidis, N. | N/A | Simulations reveal how touchdown kinematic variables affect top sprinting speed: implications for coaching | |
| 通过多模态学习实现大规模蛋白质数据的递归清洗 | Jiang, Z. | N/A | Recursive Cleaning for Large-scale Protein Data via Multimodal Learning | |
| 利用加权蛋白质-蛋白质相互作用网络进行人类必需基因的深度预测 | Mehrpou, S. | N/A | Deep Prediction of Human Essential Genes using Weighted Protein-Protein Interaction Networks | |
| 一个基于化合物生物活性谱的扩散模型，用于预测高内涵图像 | Cook, S. | N/A | A diffusion model conditioned on compound bioactivity profiles for predicting high-content images | |
| 对来自全球的象草（Cenchrus purpureus）进行全基因组重测序，以探索全球种群结构及控制产量和饲料质量性状的QTL | Teshome, A. | N/A | Whole genome resequencing of a global collection of Napier grass (Cenchrus purpureus) to explore global population structure and QTL governing yield and feed quality traits | |
| SAMPL-seq揭示了人类肠道微生物组中的微米级空间枢纽 | Richardson, M. | N/A | SAMPL-seq reveals micron-scale spatial hubs in the human gut microbiome | |
| 关于“快速封盖移除”的科学笔记——一种评估蜜蜂（Apis mellifera）幼虫感染Tropilaelaps mercedesae的方法 | Uzunov, A. | N/A | A scientific note on "Rapid brood decapping" - a method for assessment of honey bee (Apis mellifera) brood infestation with Tropilaelaps mercedesae | |
| 解码难以理解的声音：在低信噪比条件下的神经语音追踪 | He, X. | N/A | Decoding the Unintelligible: Neural Speech Tracking in Low Signal-to-Noise Ratios | |
| 深度聚焦：一种通过鼻腔途径优化奖赏环路节点深部脑刺激的方法 | Guo, Y. | N/A | DeepFocus: A Transnasal Approach for Optimized Deep Brain Stimulation of Reward Circuit Nodes | |
| 亚单位mRNA鸡尾酒疫苗的选择、设计和免疫原性研究：针对特定免疫反应谱的ASFV抗原 | Yuan, F. | N/A | Selection, Design and Immunogenicity Studies of ASFV Antigens for Subunit mRNA Cocktail Vaccines with Specific Immune Response Profiles | |
| 鼻内注射血凝素蛋白增强剂可诱导强效的黏膜免疫，并提供针对甲型流感病毒攻击的交叉保护。 | Moriyama, M. | N/A | Intranasal hemagglutinin protein boosters induce robust mucosal immunity and cross-protection against influenza A viral challenge | |
| 从具有一个时间戳和多个观测值的生态时间序列中进行因果发现 | Bystrova, D. | N/A | Causal discovery from ecological time-series with one timestamp and multiple observations | |
| 在系统发育和生态学上界定的物种库影响了对依赖年龄的灭绝的推断。 | Goncalves-Neto, S. | N/A | Phylogenetically and ecologically delimited species pool affect the inference of age-dependent extinction | |
| 一种新发现的苋属植物（Amaranthus palmeri）染色体外环状DNA中的基因组重排，使其同时对草甘膦和草铵膦两种除草剂产生抗性。 | Carvalho-Moore, P. | N/A | A Novel Genomic Rearrangement in the Amaranthus palmeri Extrachromosomal Circular DNA Provides Dual Herbicide Resistance to Glyphosate and Glufosinate | |
| PRC2促进了幼苗萌发过程中从异养到自养的转变 | Samo, N. | N/A | PRC2 facilitates the transition from heterotrophy to photoautotrophy during seedling emergence | |
| 早期经历对野生果蝠的觅食行为影响更大，超过了它们原本的行为倾向。 | Rachum, A. | N/A | Early experience affects foraging behavior of wild fruit-bats more than their original behavioral predispositions | |
| 海马体与皮层在社交记忆巩固中的相互作用 | Park, G. | N/A | Hippocampal-cortical interactions in the consolidation of social memory | |
| 黑猩猩展示中的情境依赖性节奏性 | van der Vleuten, B. | N/A | Context-dependent Rhythmicity in Chimpanzee Displays | |
| 利用迁移学习预测蛋白质-小分子相互作用 | Wang, J. | N/A | Leveraging Transfer Learning for Predicting Protein-Small Molecule Interactions | |
| 奖励驱动的小脑爬行纤维活动影响神经和行为学习 | Jin, S. | N/A | Reward-driven cerebellar climbing fiber activity influences both neural and behavioral learning | |
| 一种针对恒河猴的新型表观遗传时钟揭示了早期生活逆境与表观遗传年龄加速之间的关联 | Bronk, G. | N/A | A novel epigenetic clock for rhesus macaques unveils an association between early life adversity and epigenetic age acceleration | |
| 饮酒性依赖地改变小鼠皮层IL-1β突触信号传导和认知行为 | Liss, A. | N/A | Ethanol drinking sex-dependently alters cortical IL-1β synaptic signaling and cognitive behavior in mice | |
| 在顶叶和前额叶皮层中，逐步分离运动和认知序列 | Doyle, H. | N/A | Ramping dissociates motor and cognitive sequences in the parietal and prefrontal cortices | |
| 刚地弓形虫入侵宿主细胞时，穿孔宿主细胞质膜需要棒状体胞吐作用。 | Male, F. | N/A | Perforation of the host cell plasma membrane during Toxoplasma gondii invasion requires rhoptry exocytosis | |
| 用于自动收集培养细胞时间分辨代谢组学数据的LC-MS系统 | Chan, C. C. Y. | N/A | LC-MS system for automatically collecting time-resolved metabolomics data of cultured cells | |
| 退耕还草对土壤原核生物、真菌和原生生物的复杂响应 | Tosi, M. | N/A | Complex responses of soil prokaryotes, fungi and protists to prairie restoration on retired agricultural lands | |
| 因果中介中的高维混淆：双重机器学习与正则化偏相关网络的比较研究 | Chen, M. | N/A | High-dimensional confounding in causal mediation: a comparison study of double machine learning and regularized partial correlation network | |
| 整合接合元件对SOS反应和同源重组的调控 | Garcia Heredia, A. | N/A | Regulation of the SOS response and homologous recombination by an integrative and conjugative element | |
| 染色质环境对DOT1L在雄性生殖细胞基因表达中的影响 | Coulee, M. | N/A | Chromatin Environment-Dependent Effects of DOT1L on Gene Expression in Male Germ Cells | |
| 胎儿肝样类器官再现了血液-肝脏微环境发育及人类多能干细胞的多能造血过程 | Rezvani, M. | N/A | Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells | |
| 丝状伪足样结构对类固醇释放至关重要 | Simon, E. | N/A | Filopodia-like Structures are Essential for Steroid Release | |
| 在人类早期多能性和细胞谱系中，WNT介导的TCF/LEF转录因子基因表达与啮齿动物模型有所不同。 | Ross, C. | N/A | WNT-mediating TCF/LEF transcription factor gene expression in early human pluripotency and cell lineages differs from the rodent paradigm | |
| 非洲爪蟾的呼吸系统揭示了四足动物在生长、再生和愈合方面的共同机制 | Perry, S. K. | N/A | The Xenopus respiratory system reveals common tetrapod mechanisms for growth, regeneration and healing | |
| 雄性是默认性别：角粪甲虫性别决定级联的功能意义 | Mitchell, L. C. | N/A | Male is the default sex: functional significance of the sex determination cascade in horned dung beetles | |
| 实验性短期热浪对野生传粉者在幼虫发育期间的体重增加和存活率产生负面影响。 | Woegler, L. | N/A | Experimental short-term heatwaves negatively impact body weight gain and survival during larval development in a wild pollinator | |
| 脊髓祖细胞中CDKN1c/p57kip2低表达促使细胞从增殖性分裂模式向神经发生性分裂模式转变 | Mida, B. | N/A | A low CDKN1c/p57kip2 expression in spinal progenitors drives the transition from proliferative to neurogenic modes of division | |
| 一种调控蟑螂卵子发生和胚胎发育的piRNA | Gonzalvo, J. | N/A | A piRNA regulating oogenesis and embryo development in cockroaches | |
| 硫蝶翅膀性二态性和鳞片细胞特化的单核转录组学研究 | Loh, L. S. | N/A | Single-nucleus transcriptomics of wing sexual dimorphism and scale cell specialization in sulphur butterflies | |
| 一种油菜素内酯受体激酶对于同型孢子蕨类植物Ceratopteris richardii的性别决定是必需的。 | Burow, K. M. | N/A | A brassinosteroid receptor kinase is required for sex determination in the homosporous fern Ceratopteris richardii | |
| Orthrus：迈向进化和功能性的RNA基础模型 | Fradkin, P. | N/A | Orthrus: Towards Evolutionary and Functional RNA Foundation Models | |
| 浊度感官方法：来源与水平如何塑造水生光环境与鱼类视觉生态 | Garcia, A. | N/A | A sensory approach to turbidity: How sources and levels shape aquatic light environments and fish visual ecology | |
| R2-D2：模仿《星球大战》机器人揭示了鹦鹉和椋鸟的异种声音模仿能力 | Dam, N. C. P. | N/A | Artoo-Detoo: What imitating a Star Wars droid reveals on allospecific vocal imitation in parrots and starlings | |
| 揭示社会认知中的潜在动态：多智能体逆强化学习 | Chen, Y. | N/A | Unveiling the latent dynamics in social cognition with multi-agent inverse reinforcement learning | |
| 强迫性应对策略与适应性应对策略的肾上腺素能和巴甫洛夫基础 | Chernoff, C. S. | N/A | Noradrenergic and Pavlovian underpinnings of compulsive versus adaptive coping strategies | |
| 和弦的协和性：三和弦中每个音的半音变化对其感知协和性的影响 | Varkevisser, J. | N/A | The consonance of chords: The effect of subsemitone changes to each of the notes in a trichord on its perceived consonance | |
| X-Tracker：非洲爪蟾蝌蚪视觉回避行为的自动化分析 | McKeown, C. R. | N/A | X-Tracker: Automated Analysis of Xenopus Tadpole Visual Avoidance Behavior | |
| 解开苯基琥珀酸合酶的对映选择性机制：通过多尺度建模和动力学研究厌氧烃降解的见解 | Szaleniec, M. | N/A | Unravelling the Enantioselective Mechanism of Benzylsuccinate Synthase: Insights into Anaerobic Hydrocarbon Degradation Through Multiscale Modelling and Kinetics | |
| 一种能够合成自身及其互补链的聚合酶核酶 | Gianni, E. | N/A | A polymerase ribozyme that can synthesize both itself and its complementary strand | |
| 蛋白质组装的以键为中心的模块化设计 | Wang, S. | N/A | Bond-centric modular design of protein assemblies | |
| 利用-配对靶向RF扩散改进蛋白质结合剂设计 | Sappington, I. | N/A | Improved protein binder design using -pairing targeted RFdiffusion | |
| 定义K1样杀伤毒素的α域 | Coss, S. A. | N/A | Defining the alpha domains of K1-like killer toxins | |
| 使用贝叶斯狄利克雷过程模型建模微生物组与宿主表型之间的关联 | Awany, D. | N/A | Modelling Microbiome Association with Host Phenotypes Using a Bayesian Dirichlet Process Model | |
| 多巴胺D2受体对分离斑马鱼鳃中氧感受器的抑制作用 | Reed, M. | N/A | Oxygen chemoreceptor inhibition by dopamine D2 receptors in isolated zebrafish gills | |
| 通过超高效液相色谱-四极杆飞行时间质谱（UPLC-QTOF-MS）和气相色谱-串联质谱（GC-MS/MS）分析以及体外生物活性评估，对印度山蚂蝗（Desmodium gangeticum DC.）进行化学特征分析。 | Jagtap, M. A. | N/A | Chemo-Profiling by UPLC-QTOF-MS, GC-MS/MS analysis and In Vitro Bioactivity Assessment of Desmodium gangeticum DC. | |
| 味觉处理的演变改变了饮食偏好 | Bertolini, E. | N/A | Evolution of taste processing shifts dietary preference | |
| 语义抑制与再激活：从语义理解到审美欣赏的超越——来自审美阅读的fNIRS证据 | Liu, H. | N/A | Semantic Inhibition and Reactivation for Transcending from Semantic Understanding to Aesthetic Appreciation: fNIRS Evidence from Aesthetic Reading | |
| 单分子表征：Aducanumab、Lecanemab、Gantenerumab 和 Donanemab 对可溶性β淀粉样蛋白聚集体的结合特性 | Fertan, E. | N/A | Single-molecule characterisation of soluble beta-amyloid aggregate binding by Aducanumab, Lecanemab, Gantenerumab, and Donanemab | |
| 认知需求和听觉噪音对姿势动态的影响 | Carey, S. | N/A | Influence of Cognitive Demand and Auditory Noise on Postural Dynamics | |
| HDAC抑制剂在体外重现了与人类疾病相关的小胶质细胞特征 | Haage, V. C. | N/A | HDAC Inhibitors recapitulate Human Disease-Associated Microglia Signatures in vitro | |
| 自闭症谱系障碍啮齿动物模型中依赖于活动的整体内吞作用的趋同性抑制。 | Bonnycastle, K. | N/A | Convergent depression of activity-dependent bulk endocytosis in rodent models of autism spectrum disorders. | |
| 在人脑皮层视觉刺激过程中同时定量氧气和葡萄糖消耗 | Epp, S. M. | N/A | Simultaneous quantification of oxygen and glucose consumption during visual stimulation in the human cortex | |
| 甘氨酰-tRNA的隔离是一种统一机制，它解释了与GARS1相关的外周神经病变。 | Mora, N. | N/A | Glycyl-tRNA sequestration is a unifying mechanism underlying GARS1-associated peripheral neuropathy | |
| 一种图神经网络方法研究神经发育过程中大脑临界状态 | Cabral-Carvalho, R. M. | N/A | A Graph Neural Network Approach to Investigate Brain Critical States Over Neurodevelopment | |
| 在阿尔茨海默病敲入模型中早期破坏内嗅皮层的多巴胺 | Nakagawa, T. | N/A | Early disruption of entorhinal dopamine in a knock-in model of Alzheimer's disease | |
| SSRIs对中缝背核5-羟色胺神经元空间转录组的影响 | Henningson, C. | N/A | Effects of SSRIs on the spatial transcriptome of dorsal raphe serotonin neurons | |
| 视觉刺激的接近性降低了眼跳后的α波侧化 | Turner, C. | N/A | Proximity to Visual Stimuli Reduces Post-Saccadic Alpha Lateralisation | |
| TENM4是触觉和痛觉传导的重要转导成分。 | Khallaf, M. | N/A | TENM4 is an essential transduction component for touch and pain | |
| 亚毫米级扩散磁共振成像：采用平面内分段三维多片采集与去噪器正则化重建 | Li, Z. | N/A | Submillimeter diffusion MRI using an in-plane segmented 3D multi-slab acquisition and denoiser-regularized reconstruction | |
| 在几何网络模型中，减少节点的空间扩散能够改善与计算能力提升相关的拓扑结构。 | Christiansen, N. | N/A | Reduced spatial spread of nodes in geometric network models improves topology associated with increased computational capabilities | |
| 蜜蜂睡眠的神经相关性 | Moguilner, S. | N/A | Neuronal correlates of sleep in honey bees | |
| 期望生成及其对后续疼痛和视觉感知的影响 | Botvinik-Nezer, R. | N/A | Expectation generation and its effect on subsequent pain and visual perception | |
| tDCS颅神经协同刺激：揭示大鼠三叉神经直流电刺激涉及的脑干通路 | Majdi, A. | N/A | tDCS Cranial Nerve Co-Stimulation: Unveiling Brainstem Pathways Involved in Trigeminal Nerve Direct Current Stimulation in Rats | |
| 图雷特综合症中的丘脑-额叶连接模式：结合颅内深部脑刺激和脑电图记录的见解 | Wehmeyer, L. | N/A | Thalamo-frontal connectivity patterns in Tourette Syndrome: Insights from combined intracranial DBS and EEG recordings | |
| 淀粉样前体蛋白（Amyloid Beta Precursor Protein）有助于短命的青绿色鳉鱼（Nothobranchius furzeri）的脑老化和学习能力下降。 | de Bakker, D. E. M. | N/A | Amyloid Beta Precursor Protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri) | |
| 一种用于正电子发射断层扫描成像的μ阿片受体小分子拮抗剂放射性示踪剂。 | Plakas, K. | N/A | A Small-molecule Antagonist Radiotracer for Positron Emission Tomography Imaging of the Mu Opioid Receptor. | |
| 纹状体侧向抑制调节左旋多巴诱导的运动障碍小鼠模型中的动作选择 | Twedell, E. L. | N/A | Striatal lateral inhibition regulates action selection in a mouse model of levodopa-induced dyskinesia | |
| hMT+活动预测空间注意对周围抑制的影响 | Kiniklioglu, M. | N/A | hMT+ Activity Predicts the Effect Of Spatial Attention On Surround Suppression | |
| 大鼠岛叶皮层对刺激引导行为的贡献 | Tensaouti, Y. | N/A | Contribution of rat insular cortex to stimulus-guided action | |
| 在稳定注视和主动视觉过程中刺激特征的表征 | Moran, C. | N/A | The representation of stimulus features during stable fixation and active vision | |
| 脂质组学分析揭示了散发性帕金森病与GBA突变携带者中共享及独特的病理特征：对疾病机制的启示 | Munoz, S. S. | N/A | Lipidomic Profiling Reveals Shared and Distinct Pathological Signatures in Sporadic Parkinson's Disease and GBA Mutation Carriers: Implications for Disease Mechanisms | |
| 物体接触前后皮层抓握相关活动的变化 | Yan, Y. | N/A | Changes in cortical grasp-related activity before and after object contact | |
| 成长中的小脑：从婴儿到学龄的脑功能发育 | Lyu, W. | N/A | The Growing Little Brain: Cerebellar Functional Development from Cradle to School | |
| 食物摄入会增强海马体中的锋电波-波纹复合体。 | Kaya, E. | N/A | Food intake enhances hippocampal sharp wave-ripples | |
| 通过IP1检测，小鼠大脑中5-HT2A受体激活的快照 | de la Fuente Revenga, M. | N/A | Snapshot of 5-HT2A receptor activation in the mouse brain via IP1 detection | |
| Gasdermin D 被激活但在 SOD1G93A 模型中不驱动神经退行性变：针对细胞焦亡的潜在意义 | Gunner, G. | N/A | Gasdermin D is activated but does not drive neurodegeneration in SOD1G93A model of ALS: Implications for targeting pyroptosis | |
| 光线通过交感神经系统调节葡萄糖和脂质稳态 | Chen, X. | N/A | Light modulates glucose and lipid homeostasis via the sympathetic nervous system | |
| 脑部预靶向PET - 利用单克隆抗体成像中枢神经系统靶点的新视野 | Gustavsson, T. | N/A | Brain Pretargeted PET - New Horizons to Image CNS Targets with Monoclonal Antibodies | |
| 基于荧光寿命的FRET生物传感器用于监测活细胞中TDP-43的N端结构域相互作用：一种用于ALS和FTD药物发现的新资源 | Nathan Kochen, N. | N/A | Fluorescence lifetime-based FRET biosensors for monitoring N-terminal domain interactions of TDP-43 in living cells: A novel resource for ALS and FTD drug discovery | |
| 老年小鼠的平衡表现依赖于单极刷状细胞 | Kizeev, G. | N/A | Balance performance in aged mice is dependent on unipolar brush cells | |
| 通过抑制性突触可塑性实现递归神经回路中的结构化稳定 | Festa, D. | N/A | Structured stabilization in recurrent neural circuits through inhibitory synaptic plasticity | |
| 基底外侧杏仁核中II组代谢型谷氨酸受体的激活抑制了由辨别性刺激引发的奖赏寻求行为 | LeCocq, M. R. | N/A | Activation of Group II Metabotropic Glutamate Receptors in the Basolateral Amygdala Inhibits Reward Seeking Triggered by Discriminative Stimuli | |
| 持续性钠电流在Scn8a功能获得性小鼠中将癫痫与扩散性去极化联系起来 | Aiba, I. | N/A | Persistent Na+ current couples seizure with Spreading depolarization in Scn8a gain-of-function mice | |
| 溶栓通过依赖于血管内皮生长因子B（VEGF-B）对脂肪分解的影响，加剧了缺血性卒中后的脑血管损伤。 | Nilsson, I. | N/A | Thrombolysis exacerbates cerebrovascular injury after ischemic stroke via a VEGF-B dependent effect on adipose lipolysis | |
| 超越CTCT：特发性震颤患者接受磁共振引导聚焦超声（VIM-MRgFUS）治疗后的远期结构变化 | Krauss, J. | N/A | Beyond the CTCT: Remote Structural Changes After VIM-MRgFUS in Essential Tremor | |
| 使用循环机制模型快速、可解释、数据驱动的神经动力学模型 | Burghi, T. B. | N/A | Rapid, interpretable, data-driven models of neural dynamics using Recurrent Mechanistic Models | |
| 多站点研究中结构脑网络的协调 | Shen, R. S. | N/A | Harmonization of Structural Brain Networks for Multi-site Studies | |
| 使用隐马尔可夫模型表征先天盲人的动态功能连接 | Pedersini, C. A. | N/A | Characterizing dynamic functional connectivity in congenitally blind people using Hidden Markov Models | |
| 特定区域的扩散去极化驱动异常的癫痫后行为 | Mitlasoczki, B. | N/A | Region-specific spreading depolarization drives aberrant post-ictal behavior | |
| 睡眠结构与阿尔茨海默病病理的区域性关联 | Buchal, A. | N/A | Regional associations of sleep architecture and Alzheimer's disease pathology | |
| 前脑岛中的温度感知预测和预测误差 | Toussaint, B. | N/A | Thermoceptive predictions and prediction errors in the anterior insula | |
| 通过遗传手段降低翻译抑制因子FMRP和4E-BP2的水平，可以保护阿尔茨海默病小鼠模型的记忆功能。 | Campos Ribeiro, F. | N/A | Genetic reduction of the translational repressors FMRP and 4E-BP2 preserves memory in mouse models of Alzheimer's disease | |
| 星形胶质细胞Kir4.1通道在脊髓损伤后痉挛中的功能贡献 | Barbay, T. | N/A | Functional contribution of astrocytic Kir4.1 channels to spasticity after spinal cord injury | |
| 多组学特征分析揭示，在Sp4突变小鼠（一种精神分裂症和双相情感障碍的遗传模型）中，全脑突触广泛紊乱，神经元和胶质细胞呈现区域特异性和年龄特异性的变化。 | Kwon, M. J. | N/A | Muti-omics characterization reveals brain-wide disruption of synapses and region- and age-specific changes in neurons and glia in Sp4 mutant mice, a genetic model of schizophrenia and bipolar disorder | |
| RiboTag RNA测序揭示脑缺血后星形胶质细胞终足中HSP70的局部翻译 | Shim, B. | N/A | RiboTag RNA Sequencing Identifies Local Translation of HSP70 In Astrocyte Endfeet After Cerebral Ischemia | |
| 嗅觉转导电流的放大实现了稀疏刺激编码 | Belonio, K. C. | N/A | Amplification of olfactory transduction currents implements sparse stimulus encoding | |
| 奥罗波切正布尼亚病毒神经感染的特征 | Connors, K. A. | N/A | Characterization of neural infection by Oropouche orthobunyavirus | |
| 微流控装置中盘基网柄菌细胞在剪切应力依赖性粘附与运动行为的定量测量 | Fakhari, S. | N/A | Quantitative measurements of shear stress-dependent adhesion and motion of Dictyostelium discoideum cells in a microfluidic device | |
| 通过单细胞多组学分析解读小鼠胚胎皮肤中的基因调控程序 | Deng, Q. | N/A | Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis | |
| STAT3信号传导增强了植入后小鼠发育期间的组织扩张 | Nichols, J. | N/A | STAT3 signalling enhances tissue expansion during postimplantation mouse development | |
| 基于CRISPR/Cas9的鸟类胚胎体内报告基因敲入 | Petit-Vargas, A. | N/A | CRISPR/Cas9-based somatic knock-in of reporters in the avian embryo in ovo | |
| 细胞信号突起在脊髓神经发生中实现动态远距离接触 | Hawley, J. | N/A | Cellular signalling protrusions enable dynamic distant contacts in spinal cord neurogenesis | |
| CellMet: 从细胞和组织中提取三维形态学指标 | Theis, S. | N/A | CellMet: Extracting 3D shape metrics from cells and tissues | |
| 鉴定果蝇变态过程的特化脂质屏障 | Lampe, L. | N/A | Identification of a specialized lipid barrier for Drosophila metamorphosis | |
| 克服倍性障碍：三倍体桥梁在碎米荠属植物遗传渗入中的作用 | Bartolic, P. | N/A | Overcoming ploidy barriers: the role of triploid bridges in the genetic introgression of Cardamine amara | |
| 昆虫的基因组预测：以黄蜂Nasonia vitripennis翅膀形态特征为例的研究 | Xia, S. | N/A | Genomic prediction in insects: a case study on wing morphology traits in the jewel wasp Nasonia vitripennis | |
| 在模糊地形中自由觅食的猕猴重视信息 | Shahidi, N. | N/A | Freely foraging macaques value information in ambiguous terrains | |
| 在啮齿动物径向迷宫任务中，前额叶对回顾性空间工作记忆的表征 | Taliaferro, J. P. | N/A | Prefrontal representations of retrospective spatial working memory in a rodent radial maze task | |
| 当对手不在时：雄性蓝鳍鳉对雌性的攻击行为 | Karatgi, R. | N/A | When Rivals Are Absent: Male Aggression Towards Females in Bluefin Killifish | |
| 全流程三维电化学微胶囊封装类器官自动化高通量筛选平台加速罕见病药物研发 | Xu, Z. | N/A | Whole-Process 3D ECM-Encapsulated Organoid-Based Automated High-Throughput Screening Platform Accelerates Drug Discovery for Rare Diseases | |
| 复杂多途径反应动力学分析：胰岛素二聚体解离 | Jeong, K. | N/A | Analysis of the dynamics of a complex, multipathway reaction: Insulin dimer dissociation | |
| 脊髓脑脊液接触神经元是沿小鼠脊髓分布的一种保守的感觉神经元群体。 | CROZAT, E. | N/A | Spinal cerebrospinal fluid contacting neurons are a conserved sensory neuronal population along the mouse spinal cord | |
| 人类内侧颞叶中记忆形成与回忆之间时间顺序的神经编码得以保留 | Khazali, M. F. | N/A | A preserved neural code for temporal order between memory formation and recall in the human medial temporal lobe | |
| Dnajc3（HSP40）调节小鼠视神经的轴突再生 | Wang, J. | N/A | Dnajc3 (HSP40) Modulates Axon Regeneration in the Mouse Optic Nerve | |
| 改进的螺旋神经节神经元的光遗传学修饰，用于未来的光学耳蜗植入 | Thirumalai, A. | N/A | Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants | |
| 估计平均值：时间间隔摘要表征的行为和神经相关性 | Otsuka, T. | N/A | Estimating the mean: behavioral and neural correlates of summary representations for time intervals | |
| 掘土水鼠犁鼻器的神经解剖学 | Ruiz-Rubio, S. | N/A | Neuroanatomy of the Accessory Olfactory Bulb in the Fossorial Water Vole | |
| 预融合AAA+重塑目标-SNARE蛋白复合物能够实现突触传递 | White, K. I. | N/A | Pre-fusion AAA+ remodeling of target-SNARE protein complexes enables synaptic transmission | |
| 人脑视觉皮层中的行波：基于模型的MEG-EEG方法 | Grabot, L. | N/A | Traveling Waves in the Human Visual Cortex: a MEG-EEG Model-Based Approach | |
| 在Srrm2小鼠中，一种精神分裂症和神经发育障碍的遗传模型，观察到SynGAP-γ的减少、Agap3剪接的破坏以及少突胶质细胞的缺陷。 | Aryal, S. | N/A | Reduction of SynGAP-γ, disrupted splicing of Agap3, and oligodendrocyte deficits in Srrm2 mice, a genetic model of schizophrenia and neurodevelopmental disorder | |
| 斑马鱼幼鱼中脚间核的解剖和功能组织 | Wu, Y. K. | N/A | Anatomical and functional organization of the interpeduncular nucleus in larval zebrafish | |
| 星形胶质细胞的区域特化是由出生后的发育过程塑造的。 | Schroeder, M. E. | N/A | Astrocyte regional specialization is shaped by postnatal development | |
| 在自然伸手过程中猕猴前运动皮层神经元的手部位置场 | Cao, S. | N/A | Hand Position Fields of Neurons in the Premotor Cortex of Macaques during Natural Reaching | |
| 钾通道亚基Kcnn1在神经元中的过度表达延长了SOD1相关ALS和A53T α-突触核蛋白小鼠模型的生存期 | Nagy, M. | N/A | Neuronal overexpression of potassium channel subunit Kcnn1 prolongs survival of SOD1-linked ALS and A53T alpha-synuclein mouse models | |
| 可卡因的摄入和渴求在多巴胺神经元中产生不同的转录组特征 | Pollock, T. A. | N/A | Cocaine taking and craving produce distinct transcriptional profiles in dopamine neurons | |
| 在蝗虫中，衰老会减缓去极化扩散的恢复，而抗氧化剂治疗则会加速其恢复。 | Robertson, M. | N/A | Recovery from Spreading Depolarization is slowed by aging and accelerated by antioxidant treatment in locusts | |
| 实时预测和相位靶向脑振荡 | Jongejan, S. L. | N/A | Predicting and phase targeting brain oscillations in real-time | |
| 深度生成网络揭示了颞下皮层（IT）神经元的调谐特性，并预测了它们对视觉感知的影响。 | Papale, P. | N/A | Deep generative networks reveal the tuning of neurons in IT and predict their influence on visual perception | |
| 空间转录组学与免疫荧光染色的整合揭示了实验性胶质母细胞瘤中星形胶质细胞的空间异质性和可塑性 | Ghosh, M. | N/A | Integration of spatial transcriptomics with immunofluorescence staining reveals spatial heterogeneity and plasticity of astrocytes in experimental glioblastomas | |
| 星形胶质细胞中HIV-1 Nef的表达降低了伏隔核中谷氨酸转运蛋白的表达，并增加了大鼠的可卡因寻求行为。 | Pla-Tenorio, J. | N/A | Astrocytic HIV-1 Nef expression decreases glutamate transporter expression in the nucleus accumbens and increases cocaine-seeking behavior in rats | |
| 光学相干断层扫描能够对中风病变中的细胞移植引导重塑进行纵向评估。 | Adewumi, H. O. | N/A | Optical coherence tomography enables longitudinal evaluation of cell graft-directed remodeling in stroke lesions | |
| 阿尔茨海默病中线粒体功能障碍是由患者来源神经元中过量的内质网钙释放驱动的 | Mustaly-Kalimi, S. | N/A | Mitochondrial Dysfunction in Alzheimer's Disease Is Driven By Excess ER-Calcium Release in Patient-Derived Neurons | |
| 大细胞、小细胞和视锥细胞通路中空间总和的特征 | Wu, C. S. | N/A | Characteristics of spatial summation in the magnocellular, parvocellular, and koniocellular pathways | |
| 黑皮质素4受体依赖的ACTH机制在预防早期生活癫痫后的焦虑样行为和正常化星形胶质细胞蛋白中的作用 | Khalife, M. R. | N/A | Melanocortin 4 Receptor-Dependent Mechanism of ACTH in Preventing Anxiety-Like Behaviors and Normalizing Astrocyte Proteins After Early Life Seizures | |
| 人类可卡因使用障碍中腹侧纹状体的多组学和细胞类型特异性特征 | Zillich, E. | N/A | A multi-omics and cell type-specific characterization of the ventral striatum in human cocaine use disorder | |
| 重新编程的人侧脑室旁隆起前体细胞生成纹状体神经元并在亨廷顿病大鼠模型中恢复运动功能。 | McCaughey-Chapman, A. | N/A | Reprogrammed Human Lateral Ganglionic Eminence Precursors Generate Striatal Neurons and Restore Motor Function in a Rat Model of Huntington's Disease. | |
| 小脑攀爬纤维传递灵活、快速适应的奖励预测信号 | Vignali, C. | N/A | Cerebellar climbing fibers signal flexible, rapidly adapting reward predictions | |
| 沿着不同视觉通路学习的独特的皮层空间表征 | Lian, Y. | N/A | Distinct cortical spatial representations learned along disparate visual pathways | |
| 人类的BNST体积并非仅仅是两性异形的。 | Berry, S. C. | N/A | Human BNST volume is not simply sexually dimorphic | |
| 上下文依赖偏好中重复的作用 | Wagner, B. J. | N/A | The role of repetition in context-dependent preference | |
| 外周给药的TNF抑制剂对α-突触核蛋白诱导的大鼠多巴胺能神经元死亡无保护作用 | Christiansen, J. R. | N/A | Peripherally administered TNF inhibitor is not protective against α-synuclein-induced dopaminergic neuronal death in rats | |
| RIPK2对于小胶质细胞对细菌胞壁酰二肽的炎症反应至关重要，但对脂多糖的炎症反应则不然。 | Yang, C. | N/A | RIPK2 is crucial for the microglial inflammatory response to bacterial muramyl dipeptide but not to lipopolysaccharide | |
| AML体内靶向的整合型scFv鉴定与CAR T细胞生成 | Müller-Tidow, C. | N/A | Integrated scFv identification and CAR T cell generation for AML targeting in vivo | |
| 通过降解糖免疫检查点Siglec-7和-9来重塑肿瘤微环境 | Wang, C. | N/A | Reshaping the tumor microenvironment by degrading glycoimmune checkpoints Siglec-7 and -9 | |
| 在拟南芥转座元件中揭示的DNA甲基化与H3K27me3之间的全新串扰 | Hure, V. | N/A | Novel crosstalk between DNA methylation and H3K27me3 revealed at Arabidopsis transposable elements | |
| map3k1抑制了迁移性眼原基在涡虫再生中的终末分化 | Lo, K. C. | N/A | map3k1 suppresses terminal differentiation of migratory eye progenitors in planarian regeneration | |
| 在家族性肌萎缩性侧索硬化症4型中，对显性SETX突变进行等位基因特异性沉默 | Winkelsas, A. | N/A | Allele-specific silencing of a dominant SETX mutation in familial amyotrophic lateral sclerosis type 4 | |
| 新皮层分化与海马体对无意义物品及其空间位置的整合 | Nemecz, Z. | N/A | Neocortical differentiation and hippocampal integration of non-meaningful items and their spatial location | |
| # BioRxiv 2024-10-11 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| GEARBOCS：一种用于星形胶质细胞体内基因编辑的腺相关病毒工具 | Sivadasan Bindu, D. | N/A | GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes | |
| 系统性创建和表型分析在秀丽隐杆线虫中的孟德尔疾病模型：迈向大规模药物再利用 | O'Brien, T. J. | N/A | Systematic creation and phenotyping of Mendelian disease models in C. elegans: towards large-scale drug repurposing | |
| SIMVI揭示了空间组学数据中的内在状态和空间诱导状态 | Dong, M. | N/A | SIMVI reveals intrinsic and spatial-induced states in spatial omics data | |
| 通过顺序采样构建价值解释了决策中的序列依赖性 | Zylberberg, A. | N/A | Value construction through sequential sampling explains serial dependencies in decision making | |
| 年轻和年长成人在注意定向期间的心跳诱发电位 | Aprile, F. | N/A | The heartbeat-evoked potential in young and older adults during attention orienting | |
| 针对异染色质消除恶性干细胞通过重新激活逆转录元件和先天免疫途径在慢性粒单核细胞白血病中的作用 | Hidaoui, D. | N/A | Targeting Heterochromatin Eliminates Malignant Stem Cells in Chronic Myelomonocytic Leukemia Through Reactivation of Retroelements and Innate Immune pathways | |
| 查尔酮和吡唑啉衍生物的合成及其作为ELF3-MED23相互作用新型抑制剂的生物学评估 | Hwang, S.-Y. | N/A | Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction | |
| AlphaFold2在二聚体、三聚体和四聚体卷曲螺旋结构域建模中的适用性 | Madaj, R. | N/A | Applicability of AlphaFold2 in the modeling of dimeric, trimeric, and tetrameric coiled-coil domains | |
| 异质性和高阶皮质连接支撑着高效、稳健且可靠的神经编码。 | Egas Santander, D. | N/A | Heterogeneous and higher-order cortical connectivity undergirds efficient, robust and reliable neural codes | |
| 一种分子开关调控着人类信使RNA的核外输出 | Hohmann, U. | N/A | A molecular switch orchestrates the nuclear export of human messenger RNA | |
| 视觉识别深度神经网络的反复问题 | Maniquet, T. | N/A | Recurrent issues with deep neural networks of visual recognition | |
| 在尖峰神经肌肉模型中，平衡中央控制与感觉反馈能产生适应性强且稳健的蝾螈脊髓运动模式。 | Pazzaglia, A. | N/A | Balancing central control and sensory feedback produces adaptable and robust locomotor patterns in a spiking, neuromechanical model of the salamander spinal cord | |
| 拉特伦库利德海绵中独特而神秘的螺旋体共生体 | Waterworth, S. C. | N/A | The unique and enigmatic spirochete symbiont of latrunculid sponges | |
| 模拟显示，法尼醇X受体（FXR）铰链在FXR-RXR核受体异二聚体中扮演着独特的角色。 | Yu, T. | N/A | Simulations reveal unique roles for the FXR hinge in the FXR-RXR nuclear receptor heterodimer | |
| 线粒体功能障碍：揭示溃疡性结肠炎期间抗TNF反应背后的生物学机制 | Kioroglou, D. | N/A | Mitochondrial dysfunction: unraveling the elusive biology behind anti-TNF response during ulcerative colitis | |
| 在异源二倍体和四倍体群体中，基因组预测杂种优势、近交控制及配对分配 | Endelman, J. B. | N/A | Genomic prediction of heterosis, inbreeding control, and mate allocation in outbred diploid and tetraploid populations | |
| 巨噬细胞中脂肪酸的摄入或分解代谢受损会限制结核分枝杆菌的胞内生长。 | Simwela, N. V. | N/A | Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis | |
| 蛋白质表面化学编码了一种对干燥的适应性耐受性 | Romero-Perez, P. S. | N/A | Protein Surface Chemistry Encodes an Adaptive Tolerance to Desiccation | |
| 含有强效LILRB1 D1D2的抗体可抑制RIFIN介导的免疫逃避 | Wang, Y. | N/A | Potent LILRB1 D1D2-containing antibodies inhibit RIFIN-mediated immune evasions | |
| SynDRep：一种基于协同伙伴预测的药物重定位知识图谱增强工具 | Shalaby, K. S. | N/A | SynDRep: A Knowledge Graph-Enhanced Tool based on Synergistic Partner Prediction for Drug Repurposing | |
| 重新思考大规模系统基因组学：PhyloToL 6，一个灵活的工具包，用于实现基于系统发育的数据管理和分析 | Cote-L'Heureux, A. E. | N/A | Rethinking large scale phylogenomics with PhyloToL 6, a flexible toolkit to enable phylogeny-informed data curation and analysis | |
| 旁分泌拯救MYR1缺陷型刚地弓形虫突变体揭示了体内CRISPR筛选的局限性 | Torelli, F. | N/A | Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens | |
| 大型丝氨酸整合酶脱靶发现与验证用于治疗性基因组编辑 | Hazelbaker, D. Z. | N/A | Large Serine Integrase Off-target Discovery and Validation for Therapeutic Genome Editing | |
| 利用跨试验和行为会话的相关性来改进神经解码 | Zhang, Y. | N/A | Exploiting correlations across trials and behavioral sessions to improve neural decoding | |
| 使用深度学习和基于物理的专家混合进行稳健的RNA二级结构预测 | Qiu, X. | N/A | Robust RNA Secondary Structure Prediction with a Mixture of Deep Learning and Physics-based Experts | |
| 前额叶皮层中的视觉运动神经元进行的贝叶斯推理 | Langlois, T. | N/A | Bayesian inference by visuomotor neurons in prefrontal cortex | |
| 模块化表示出现在经过训练以执行依赖于上下文的任务的神经网络中 | Johnston, W. J. | N/A | Modular representations emerge in neural networks trained to perform context-dependent tasks | |
| 动物声学交流保持着一种普遍的最优节奏 | Piette, T. | N/A | Animal acoustic communication maintains a universal optimum rhythm | |
| 生物信息学：整合负对照以获得优质数据 | van Nues, R. W. | N/A | Bio-informatics: Integrate negative controls to get the good data | |
| 哥伦比亚大西洋省韦莱罗港高沉积物水域中珊瑚种群及其相关生物的空前发现 | Moreno Tilano, J. A. | N/A | Unprecedented sighting of coral populations and associated fauna in the High Sedimentation Waters of Puerto Velero, Atlantico, Colombia | |
| 雌激素缺乏改变血管化和矿化动力学：来自新型三维人源化和血管化骨类器官模型的见解 | Bukhari, M. M. M. | N/A | Estrogen Deficiency alters Vascularization and Mineralization dynamics: insight from a novel 3D Humanized and Vascularized Bone Organoid Model | |
| 剖析人类诱导多能干细胞模型中MASLD进展过程中的复合肝细胞损伤 | Weihs, J. | N/A | Dissecting compounded hepatocyte injury in a model of MASLD progression from human induced pluripotent stem cells | |
| 小GTP酶Ran定义了核孔复合物的非对称性。 | Sachweh, J. | N/A | The small GTPase Ran defines Nuclear Pore Complex asymmetry | |
| cGAS缺陷小鼠表现出与LINE1元件去抑制和炎症相关的早衰现象。 | Martinez, J. C. | N/A | cGAS deficient mice display premature aging associated with de-repression of LINE1 elements and inflammation | |
| 一种非典型的E3泛素连接酶在营养压力期间保护核糖体 | Douglas, T. | N/A | An atypical E3 ligase safeguards the ribosome during nutrient stress | |
| BBSome的功能多样化：来自蜜蜂锥虫寄生虫Lotmaria passim的见解 | Yuan, X. | N/A | Functional diversification of the BBSome: Insights from honey bee trypanosomatid parasite, Lotmaria passim | |
| Plexin/Semaphorin拮抗作用通过接触间充质化调控集体细胞迁移、间隙闭合和器官塑形 | Bischoff, M. C. | N/A | Plexin/Semaphorin Antagonism Orchestrates Collective Cell Migration, Gap Closure and Organ sculpting by Contact-Mesenchymalization | |
| Nth-like DNA糖基化酶对线粒体动力学的影响 | Hubers, L. A. | N/A | Functional Impact of Nth-like DNA glycosylase on Mitochondrial Dynamics | |
| GPR87在肺纤维化中的作用 | Khoury, J. | N/A | The role of GPR87 in Pulmonary Fibrosis | |
| Danicamtiv通过减少肌球蛋白的工作冲程，同时激活细丝来增强收缩。 | Scott, B. | N/A | Danicamtiv reduces myosin's working stroke but enhances contraction by activating the thin filament | |
| 配体结合的TRPV1异质性：冷冻电镜与分子动力学模拟方法的比较 | Astore, M. A. | N/A | Heterogeneity in ligand-bound TRPV1: A comparison of methods in cryo-EM and molecular dynamics simulation | |
| 骨髓基质细胞之间的隧道纳米管支持传递自噬和多发性骨髓瘤的抗凋亡作用。 | Solimando, A. G. | N/A | Tunneling Nanotubes Between Bone Marrow Stromal Cells Support Transmitophagy and Resistance to Apoptosis in Myeloma | |
| 绘制接受氟达拉滨治疗的白血病细胞的空间蛋白质组图谱 | Globisch, M. A. | N/A | Mapping the Spatial Proteome of Leukemia Cells Undergoing Fludarabine Treatment | |
| 细胞外谷胱甘肽的分解代谢为肿瘤生长提供了氨基酸支持。 | Hecht, F. | N/A | Catabolism of extracellular glutathione supplies amino acids to support tumor growth | |
| 一项大规模的反向遗传学筛选鉴定出多个调控睾丸新生肌管集体细胞迁移和集体器官塑形的调控因子 | Bischoff, M. C. | N/A | A large reverse-genetic screen identifies numerous regulators of testis nascent myotube collective cell migration and collective organ sculpting | |
| 货物适配器身份控制驱动蛋白激活的机制和动力学 | Gillies, J. P. | N/A | Cargo adaptor identity controls the mechanism and kinetics of dynein activation | |
| FUDR的磷酰胺酸修饰物NUC-3373，可导致结直肠癌细胞DNA损伤并释放损伤相关分子模式（DAMPs），从而增强淋巴细胞诱导的细胞死亡。 | read, o. | N/A | A phosphoramidate modification of FUDR, NUC-3373, causes DNA damage and DAMPs release from colorectal cancer cells, potentiating lymphocyte-induced cell death | |
| 从福尔马林固定石蜡包埋（FFPE）样本中进行可靠的RNA测序分析，作为加速癌症相关健康差异研究的一种手段 | Sandulache, V. | N/A | Reliable RNA-seq analysis from FFPE specimens as a means to accelerate cancer-related health disparities research | |
| 从福尔马林固定石蜡包埋（FFPE）样本中进行可靠的RNA测序分析，作为加速癌症相关健康差异研究的一种手段 | Sandulache, V. | N/A | Reliable RNA-seq analysis from FFPE specimens as a means to accelerate cancer-related health disparities research | |
| 甲状腺癌中可靶向治疗的耐药性与克隆性造血相关 | Tiedje, V. | N/A | Targetable Treatment Resistance in Thyroid Cancer with Clonal Hematopoiesis | |
| 富含多酚的岩白菜（Bergenia ligulata (Wall.) Engl.）提取物在体内增强结肠和乳腺癌转移：细胞类型特异性机制的证据 | De, S. | N/A | Polyphenol-rich fraction of Bergenia ligulata (Wall.) Engl. sensitizes colon and breast cancer metastasis in vivo: Evidence of cell-type specific mechanism | |
| 易位可以驱动调控子中多个基因的表达变化，这些调控子覆盖整个染色体臂。 | Oncins, A. | N/A | Translocations can drive expression changes of multiple genes in regulons covering entire chromosome arms | |
| PKCtheta-GADD45a轴的丧失促使三阴性乳腺癌细胞进入p53非依赖性衰老状态。 | Nicolle, A. | N/A | Loss of PKCtheta-GADD45a axis drives triple-negative breast cancer cells into p53-independent senescence | |
| CXCR4部分激动剂通过靶向多形核髓源性抑制细胞和癌症驱动的粒细胞生成，改善了免疫疗法的效果。 | Qian, J. | N/A | A CXCR4 partial agonist improves immunotherapy by targeting polymorphonuclear myeloid-derived suppressor cells and cancer-driven granulopoiesis | |
| 基于性别和年龄的小鼠原代腹膜间皮细胞蛋白质组特征分析与比较 | Wang, Z. | N/A | Gender- and Age-Based Characterization and Comparison of the Murine Primary Peritoneal Mesothelial Cell Proteome | |
| 癌症mRNA翻译特异性介质的筛选 | Kovalski, J. R. | N/A | Functional screen for mediators of onco-mRNA translation specificity | |
| 别构降解剂诱导CRL5ASB8介导的XPO1降解 | Hudman-Wing, C. E. | N/A | Allosteric degraders induce CRL5ASB8 mediated degradation of XPO1 | |
| 利用胰凝乳蛋白酶水解法挖掘人类卵巢癌外泌体的蛋白质组 | Cooper, T. T. | N/A | Mining the Proteome of Human Ovarian Cancer Extracellular Vesicles Using Thermolysin Proteolysis | |
| 胰岛素抵抗性肥胖中的血浆外泌体加剧三阴性乳腺癌的进展 | Llevenes, P. | N/A | Plasma Exosomes in Insulin Resistant Obesity Exacerbate Progression of Triple Negative Breast Cancer | |
| Mgat4b介导的选择性N-糖基化调控黑素细胞发育及黑色素瘤进展 | Natarajan, V. T. | N/A | Mgat4b mediated selective N-glycosylation regulates melanocyte development and melanoma progression | |
| 一种肿瘤胚胎学方法揭示了SoxC驱动的结肠发育和癌症调控 | Dalessi, T. | N/A | An oncoembryology approach uncovers SoxC-driven regulation of colon development and cancer | |
| H2AK119ub动力学控制毛囊干细胞静息状态 | Flora, P. | N/A | H2AK119ub dynamics controls hair follicle stem cell quiescence | |
| 人类和大猩猩视网膜蓝锥光感受器外节中的全长隐花色素1表明其作用不仅仅局限于转录抑制。 | Bartoelke, R. | N/A | Full-length Cryptochrome 1 in the outer segments of the retinal blue cone photoreceptors in humans and great apes suggests a role beyond transcriptional repression | |
| 一种结直肠癌中三级淋巴结构数字表征的新方法 | Munoz-Erazo, L. | N/A | A novel approach to digital characterisation of Tertiary Lymphoid Structures in colorectal cancer | |
| 鉴定DLK1（一种Notch配体）作为免疫治疗靶点及调节肾上腺皮质癌肿瘤细胞可塑性和化学抗性的作用 | Sun, N.-Y. | N/A | Identification of DLK1, a Notch ligand, as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma | |
| 由于谱系依赖的干细胞和祖细胞上的生长抑素受体表达，放射性诊断概念在神经内分泌肿瘤中的局限性 | Nguyen, N. | N/A | Limitations of the radiotheranostic concept in neuroendocrine tumors due to lineage-dependent somatostatin receptor expression on hematopoietic stem and progenitor cells | |
| 抑制雄激素受体暴露了前列腺癌的复制应激脆弱性 | Williams, C. S. | N/A | Inhibition of Androgen Receptor Exposes Replication Stress Vulnerability in Prostate Cancer | |
| 遗传数据指导下的卵巢癌最佳治疗方案 | Mertzios, A. | N/A | Optimal Prescriptive Treatments for Ovarian Cancer with Genetic Data | |
| 从年轻和年老小鼠中建立永生化的棕色和白色前脂肪细胞系 | Wu, X. | N/A | Establishing immortalized brown and white preadipocyte cell lines from young and aged mice | |
| 一种新型GelMA-OrnMA电导性生物墨水用于开发工程化神经组织 | Sakr, M. | N/A | A Novel GelMA-OrnMA Electrically Conductive Bioink for Developing Engineered Neural Tissues | |
| 解开金丝桃素的潜力：一种针对胆固醇管理中PCSK9突变的新方法 | FERRARI, I. V. | N/A | Unraveling the Potential of Hypericin: A Novel Approach to Targeting PCSK9 Mutations in Cholesterol Management | |
| 基准测试基于序列和基于AlphaFold的方法用于pMHC-II结合核心预测：各自的优势与共识方法 | Ko, S. | N/A | Benchmarking Sequence-Based and AlphaFold-Based Methods for pMHC-II Binding Core Prediction: Distinct Strengths and Consensus Approaches | |
| 利用预测的噬菌体宿主信息改进肠道噬菌体群落比较 | Shamash, M. | N/A | Improving gut virome comparisons using predicted phage host information | |
| 蛋白质聚集以特定尺寸的方式驱动大肠杆菌细胞的衰老 | Wagener, L. | N/A | Protein aggregation drives cell aging in a size-specific manner in Escherichia coli | |
| 在魏斯曼式和拉马克式继承的连续体上，文化复制的一个达尔文模型 | Zachar, I. | N/A | A Darwinian model of cultural replication over the continuum of Weismannian and Lamarckian inheritance | |
| 不同血管区对脑自动调节和功能性充血的深度依赖性贡献：一项模拟分析 | Pashaie, R. | N/A | Depth-Dependent Contributions of Various Vascular Zones to Cerebral Autoregulation and Functional; Hyperemia: An In-Silico Analysis | |
| 提高生成化学中分子字符串表示的可靠性 | Reboul, E. | N/A | Improving the reliability of molecular string representations for generative chemistry | |
| 数据驱动评估适用于改进抗体选择的合适免疫原 | Waury, K. | N/A | Data-driven evaluation of suitable immunogens for improved antibody selection | |
| Vispro 提升了 Visium 空间转录组学成像分析的效果。 | Ma, H. | N/A | Vispro improves imaging analysis for Visium spatial transcriptomics | |
| 揭示新型高糖基化人促红细胞生成素类似物：全面计算探索 | Thahsin, N. | N/A | Unveiling Novel Hyperglycosylated Analog of Human Erythropoietin: A Comprehensive Computational Exploration | |
| 迈向更环保的AlphaFold2蛋白质复合物建模协议：来自CAPRI第55轮的见解 | Savas, B. | N/A | Towards a greener AlphaFold2 protocol for protein complex modeling: Insights from CAPRI Round 55 | |
| R3DFEM：一个用于运行3D-CMCC-FEM模型的R包 | Vangi, E. | N/A | R3DFEM: an R package for running the 3D-CMCC-FEM model | |
| 定量分析Hsp100蛋白解聚酶在折叠蛋白底物上的进程性 | Banwait, J. K. | N/A | Quantitative Insights into Processivity of an Hsp100 Protein Disaggregase on Folded Protein Substrates | |
| 基于强化学习的加权集成方法的罕见事件采样 | Yang, D. | N/A | Rare-Event Sampling using a Reinforcement Learning-Based Weighted Ensemble Method | |
| 与加速亨廷顿病进展相关的FAN1点突变改变了其在DNA上的PCNA介导的组装 | Aretz, J. | N/A | A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA | |
| 嗜酸性粒细胞主要碱性蛋白-1的原位晶体结构 | Yang, J. E. | N/A | In situ crystalline structure of the Eosinophil major basic protein-1 | |
| 编织DNA的几何结构决定了超螺旋的分布 | Hong, Y. | N/A | Geometry of Braided DNA Dictates Supercoiling Partition | |
| 无序蛋白质：微相还是关联聚合物？ | Girard, M. | N/A | Disordered proteins: microphases or associative polymers? | |
| 通过深度学习和协同进化分析揭示的细胞质苹果酸脱氢酶的热适应性 | Shukla, D. | N/A | Thermal Adaptation of Cytosolic Malate Dehydrogenase Revealed by Deep Learning and Coevolutionary Analysis | |
| 细胞穿透肽对膜破坏的计算研究 | Catalina-Hernandez, E. | N/A | Computational Insights into Membrane Disruption by Cell-Penetrating Peptides | |
| 生物膜上的质子迁移：脂质相、温度及成分对质子传递过程及膜质子屏障的依赖性 | Ramanthrikkovil Variyam, A. | N/A | Proton migration on biological membranes: Lipid phase, temperature, and composition dependence of proton transfer processes and membrane proton barrier | |
| 我们能否开发出理想的RNA力场？从UUCG RNA四核苷酸环及其他系统的模拟中获得的启示。 | Mlynsky, V. | N/A | Can We Ever Develop an Ideal RNA Force Field? Lessons Learned from Simulations of UUCG RNA Tetraloop and Other Systems. | |
| 内在无序蛋白质的序列-集合-功能关系的广义设计 | Krueger, R. | N/A | Generalized design of sequence-ensemble-function relationships for intrinsically disordered proteins | |
| 混合蛋白质溶液中的扩散与粘度 | Wozniak, S. | N/A | Diffusion and Viscosity in Mixed Protein Solutions | |
| Afadin 介导了与协同结合和肌动蛋白丝曲率相关的 F-肌动蛋白上的钙粘蛋白-连环蛋白复合物的聚集。 | Gong, R. | N/A | Afadin mediates cadherin-catenin complex clustering on F-actin linked to cooperative binding and filament curvature | |
| 阿片受体揭示了一种明确的细胞内机制，即内体G蛋白的激活 | Fisher, N. M. | N/A | Opioid receptors reveal a discrete cellular mechanism of endosomal G protein activation | |
| 通过植物RNA热敏开关控制异源蛋白合成 | Lastovka, F. | N/A | Controlling heterologous protein synthesis through a plant RNA ThermoSwitch | |
| 杏仁核亚区体积及分配在青春期前儿童中的情况——与年龄、性别和体重指数的关联 | Overholtzer, L. N. | N/A | Amygdala Subregion Volumes and Apportionment in Preadolescents -- Associations with Age, Sex, and Body Mass Index | |
| 与亚临床性淡漠相关的前额叶-运动回路 | Derosiere, G. | N/A | Fronto-motor circuits linked to subclinical apathy | |
| LPS结合的胱天蛋白酶激活和募集结构域（CARDs）是二分体的脂质结合模块。 | Cao, A. B. | N/A | LPS binding caspase activation and recruitment domains (CARDs) are bipartite lipid binding modules | |
| 抗体-Fab和-Fc特性促进结核分枝杆菌的限制。 | Grace, P. S. | N/A | Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction. | |
| 巨细胞病毒与脑萎缩在不同人群中免疫衰老轨迹的关系 | Touil, H. | N/A | Relation of CMV and brain atrophy to trajectories of immunosenescence in diverse populations | |
| 铜绿假单胞菌中葡糖胺基磷脂酰甘油的生物合成 | Khan, F. Z. | N/A | Biosynthesis of glucosaminyl phosphatidylglycerol in Pseudomonas aeruginosa | |
| 跨代效应改变了表型可塑性的适应性后果及其调控途径的遗传结构 | Bogan, S. N. | N/A | Transgenerational effects alter the fitness consequences and genetic architecture of phenotypic plasticity and its regulatory pathways | |
| 良好的系统发育分析揭示了蝶形花科豆科植物多样化过程中龙骨瓣花的多次起源。 | Cai, L. | N/A | Well-resolved phylogeny reveals multiple origins of keel flowers during the diversification of papilionoid legumes | |
| 完整的参考基因组和泛基因组扩展了使用短读长测序和阵列数据进行全基因组DNA甲基化分析的生物学相关信息 | Dong, Z. | N/A | Complete Reference Genome and Pangenome Expand Biologically Relevant Information for Genome-Wide DNA Methylation Analysis Using Short-Read Sequencing and Array Data | |
| 染色体水平的高分辨率单倍型解析基因组组装为深入了解意大利黑麦草（Lolium multiflorum Lam.）的高度杂合基因组提供了见解。 | Chen, Y. | N/A | Chromosome-level haplotype-resolved genome assembly provides insights into the highly heterozygous genome of Italian ryegrass (Lolium multiflorum Lam.) | |
| 评估一种高通量质谱方法，利用体积吸收微采样（VAMS）设备加速临床癌症队列中的生物标志物发现。 | Lucas, N. | N/A | Assessment of a high-throughput mass spectrometry method to accelerate biomarker discovery in clinical cancer cohorts using volumetric absorptive microsampling (VAMS) devices. | |
| ProFit-1D用于在3T磁场下量化J差异编辑数据 | Chan, K. L. | N/A | ProFit-1D for quantifying J-difference edited data at 3T | |
| 使用从头设计的激动剂调整胰岛素受体信号传导 | Wang, X. | N/A | Tuning Insulin Receptor Signaling Using De Novo Designed Agonists | |
| 纳米抗体表位预测中的AI驱动方法：我们是否已经到达？ | Eshak, F. | N/A | AI driven approaches in Nanobody Epitope Prediction: Are We There Yet? | |
| 构建：一种用于识别蛋白质三级结构中功能性或结构重要区域的算法工具 | Chivot, L. | N/A | CONSTRUCT: an algorithmic tool for identifying functional or structurally important regions in protein tertiary structure | |
| LipiDetective - 一种用于在串联质谱中识别分子脂质种类的深度学习模型 | Wuerf, V. | N/A | LipiDetective - a deep learning model for the identification of molecular lipid species in tandem mass spectra | |
| 可解释的多组学整合：基于UMAP嵌入和密度聚类的分析 | Castellano-Escuder, P. | N/A | Interpretable multi-omics integration with UMAP embeddings and density-based clustering | |
| 阿波罗：一种综合性的基于主机的GPU加速模拟器，用于模拟病毒进化和感染动力学在人群、组织和细胞间的传播过程。 | Perera, D. | N/A | Apollo: A comprehensive GPU-powered within-host simulator for viral evolution and infection dynamics across population, tissue, and cell | |
| 精氨酸甲基化与磷酸化协同作用，调控NADP+的合成 | Zhu, Y. | N/A | Arginine methylation coordinates with phosphorylation to regulate NADP+ synthesis | |
| 基于RSPO4的靶向LGR4/5/6的喜树碱类似物偶联物在结直肠癌临床前模型中的抗肿瘤活性研究。 | Toh, Y. | N/A | Anti-tumor activity of camptothecin analog conjugate of a RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer. | |
| 体内双光子荧光寿命成像技术解析了玉米维管束鞘细胞的光合特性 | Chen, Z. | N/A | In vivo two-photon FLIM resolves photosynthetic properties of maize bundle sheath cells | |
| 肌联蛋白H样蛋白条件性缺失对心脏功能的影响。 | Burnham, H. V. | N/A | The effects of conditional loss of myosin binding protein H-like on cardiac function. | |
| 利用量子点纳米颗粒追踪活体内促性腺激素释放激素介导的运动：对精子释放途径的深入了解 | Julien, A. R. | N/A | Tracking gonadotropin-releasing hormone-mediated movement in-vivo using quantum dot nanoparticles: insights into pathways leading to sperm release | |
| 成熟树干钻孔处理前后树液流速的空间变化 | Umebayashi, T. | N/A | Spatial variations in sap flow rates in mature tree stems before and after drilling treatment | |
| 单细胞RNA测序数据在预测植物代谢途径基因中的应用 | Ma, J. | N/A | The utility of single-cell RNA sequencing data in predicting plant metabolic pathway genes | |
| 植物抵抗丁香假单胞菌的抗性中，水分免疫优先于气孔免疫。 | Kemppinen, J. | N/A | Water immunity overrides stomatal immunity in plant resistance to Pseudomonas syringae | |
| NPF4.1 将胚胎衍生的 GA4 导入胚乳，以促进种子萌发 | Sirlin-Josserand, M. | N/A | NPF4.1 imports embryo-derived GA4 to the endosperm to promote seed germination | |
| 计算微生物组药理学分析阐明了阴道微生物及其代谢物的抗癌潜力 | Lawore, D. C. | N/A | Computational Microbiome Pharmacology Analysis Elucidates the Anti-Cancer Potential of Vaginal Microbes and Metabolites | |
| 成人生命周期中成功视觉短时记忆的多个神经通路 | Jansen, M. G. | N/A | Multiple neural pathways to successful visual short-term memory across the adult lifespan | |
| 在人类内侧前额叶皮层中，随着巩固过程的进行，一个抽象的关系图谱逐渐显现。 | Baram, A. | N/A | An abstract relational map emerges in the human medial prefrontal cortex with consolidation | |
| 扩展数学框架以研究在存在小胶质细胞包绕情况下的神经元动力学 | Garcia, N. | N/A | Extending mathematical frameworks to investigate neuronal dynamics in the presence of microglial ensheathment | |
| 多巴胺和皮质iPSC衍生的神经元在不同的帕金森病突变中表现出溶酶体和线粒体功能障碍的差异：这对蛋白质沉积与选择性细胞丢失的意义 | Chedid, J. | N/A | Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss | |
| 口服避孕药对大脑网络的影响：一项重复和扩展研究 | Haase, G. | N/A | Effects of oral contraceptive pills on brain networks: A replication and extension | |
| 同位素编码化学成像识别淀粉样斑块年龄依赖性结构成熟、突触丧失及毒性增加 | Wood, J. I. | N/A | Isotope Encoded Chemical Imaging Identifies Amyloid Plaque Age Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity | |
| 纵向多组学揭示了TSC2致病变异扰乱了从结节性硬化症复杂病变中衍生的人类皮层类器官的发育轨迹 | Niu, W. | N/A | Longitudinal multi-omics reveals pathogenic TSC2 variants disrupt developmental trajectories of human cortical organoids derived from Tuberous Sclerosis Complex | |
| 长期记忆从优先和非优先状态中提取的工作记忆效果 | Born, F. | N/A | Long-Term Effects of Working Memory Retrieval From Prioritized and Deprioritized States | |
| T-scope V4：用于自由活动动物光遗传标记的微型显微镜 | Wang, Y. | N/A | T-scope V4: miniaturized microscope for optogenetic tagging in freely behaving animals | |
| 在灵长类动物的初级视觉皮层（V1）中，外周表征的活动在奔跑过程中会显著地受到调节。 | Rowley, D. P. | N/A | Activity in the peripheral representation within primate V1 is substantially modulated during running | |
| R21/Matrix-M疟疾疫苗诱导的抗体库、功能和结构 | McDaniel, J. R. | N/A | Repertoire, function, and structure of serological antibodies induced by the R21/Matrix-M malaria vaccine | |
| IgG自身抗体在类天疱疮中直接诱导角质形成细胞中依赖于MyD88的促炎性反应，从而导致病理性炎症反应： | Bao, L. | N/A | IgG autoantibodies in bullous pemphigoid directly induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes: | |
| 代谢组学分析揭示脂肪酸在慢性病毒感染期间作为调节干细胞样耗竭CD8 T细胞的潜力 | Kazane, K. R. | N/A | Metabolomic Profiling Reveals Potential of Fatty Acids as Regulators of Stem-like Exhausted CD8 T Cells During Chronic Viral Infection | |
| 研究儿童大脑和生物发育及其与身体、心理和学业成果的关系 | Chang, H. | N/A | Investigating Brain and Biological Development in Children and Their Relationship with Physical, Mental, and Academic Outcomes | |
| 降水变化驱动草原功能群间相互作用及短期瞬时不稳定性的差异：一种基于阶段结构群落的方法 | Gupta, A. | N/A | Variation in precipitation drives differences in interactions and short-term transient instability between grassland functional groups: a stage-structured community approach | |
| 冰川后遗传遗产、人口统计学与气候变化：为银冷杉制定保护优先事项 | Balao, F. | N/A | Postglacial Genetic Legacies, Demography, and Climate Change: Setting Conservation Priorities for Silver Fir | |
| 软组织体积对骨骼气腔化程度估计的影响：对古鸟类动物的启示 | Burton, M. G. | N/A | The influence of soft tissue volume on estimates of skeletal pneumaticity: implications for fossil archosaurs | |
| TP53 微基因分析的 161 个序列变化提供了空间约束和调控元件对变异诱导剪接影响的证据。 | Canson, D. M. | N/A | TP53 minigene analysis of 161 sequence changes provides evidence for role of spatial constraint and regulatory elements on variant-induced splicing impact | |
| 吞噬作用中的蛋白激酶：癌症的潜在遗传生物标志物 | Arumilli, S. | N/A | Protein Kinases in Phagocytosis: Promising Genetic Biomarkers for Cancer | |
| 基于组织异质性的对比增强光学相干弹性成像在乳腺癌可视化中的应用 | Li, J. | N/A | Visualization of breast cancer using contrast-enhanced optical coherence elastography based on tissue heterogeneity | |
| 基准测试用于抗体设计的生成模型 | Ucar, T. | N/A | Benchmarking Generative Models for Antibody Design | |
| InteracTor：一种新的综合特征提取工具包，用于改进蛋白质结构性质的表征 | Silva, J. C. F. | N/A | InteracTor: A new integrative feature extraction toolkit for improved characterization of protein structural properties | |
| 鉴定葡萄膜黑色素瘤中可靶向的表观遗传脆弱性 | Yenisehirli, G. | N/A | Identification of targetable epigenetic vulnerabilities in uveal melanoma | |
| 解决深度学习中的领域偏移问题：从植物病害诊断和花卉识别中获得的挑战与见解 | Sun, J. | N/A | Addressing domain shift in deep learning: Challenges and insights from plant disease diagnosis and flower recognition | |
| 基于随机化的不同拓扑和癌症表达特征的相互作用基因对的评估 | Dalgic, E. | N/A | Randomization based evaluation of distinct topological and cancer expression characteristics of mutually acting gene pairs | |
| 使用多传感器地理定位器和稳定同位素揭示的高纬度繁殖鸣禽（Setophaga coronata coronata）的迁徙策略 | Szarmach, S. J. | N/A | Migration strategies of a high-latitude breeding songbird (Setophaga coronata coronata) revealed using multi-sensor geolocators and stable isotopes | |
| 研究合生干预对健康年轻女性工作记忆表现的影响 | Salimi, Y. | N/A | Investigating the Effects of Synbiotic Intervention on Working Memory performance in Healthy Young Women | |
| ORCO：Ollivier-Ricci曲率-组学：一种用于分析生物系统鲁棒性的无监督方法 | Simhal, A. K. | N/A | ORCO: Ollivier-Ricci Curvature-Omics: an unsupervised method for analyzing robustness in biological systems | |
| 基于pA-Tn5插入模式的TIP-seq峰值调用参数的合理设计提高了预测能力 | Roberts, T. | N/A | Rational design of peak calling parameters for TIP-seq based on pA-Tn5 insertion patterns improves predictive power | |
| 全基因组CRISPR/Cas9筛选揭示影响肿瘤细胞对NK细胞介导杀伤敏感性的因素 | Guia, S. | N/A | Genome-wide CRISPR/Cas9 screen reveals factors that influence the susceptibility of tumor cells to NK cell-mediated killing | |
| 头孢吡肟-他尼巴坦和头孢布坦-莱达巴坦对导致头孢他啶-阿维巴坦耐药的KPC变异株保持活性 | Myers, C. L. | N/A | Cefepime-Taniborbactam and Ceftibuten-Ledaborbactam Maintain Activity Against KPC Variants that Lead to Ceftazidime-Avibactam Resistance | |
| MEDOC：一种快速、可扩展且在数学上精确的算法，用于在大规模无序蛋白质中进行位点特异性的质子化程度预测 | Fossat, M. J. | N/A | MEDOC: A fast, scalable and mathematically exact algorithm for the site-specific prediction of the protonation degree in large disordered proteins | |
| 对SARS-CoV-2核衣壳C端结构域RNA结合抑制剂的结构见解 | Dhaka, P. | N/A | Structural insights into the RNA binding inhibitors of the C-terminal domain of the SARS-CoV-2 nucleocapsid | |
| 柴-1：解码生命的分子相互作用 | Chai Discovery (Chai), | N/A | Chai-1: Decoding the molecular interactions of life | |
| 小锚蛋白重复蛋白对SARS-CoV-2变种的功能活性与结合特异性 | Park, Y.-J. | N/A | Functional Activity and Binding Specificity of small Ankyron Repeat Proteins against SARS-CoV-2 variants | |
| 人类扁桃体类器官揭示了调节ChAdOx1体液和细胞反应的先天通路 | Pudjohartono, M. F. | N/A | Human tonsil organoids reveal innate pathways modulating humoral and cellular responses to ChAdOx1 | |
| 北极洋病毒群落：季节性、两极性及原核生物相互作用 | Calayag, A. | N/A | Arctic Ocean virus communities: seasonality, bipolarity, and prokaryotic interactions | |
| 弧菌可能是欧洲沿海环境中新型粘菌素抗性基因的潜在来源 | Saad, J. | N/A | Vibrio are a potential source of novel colistin-resistance genes in European coastal environments | |
| 登革病毒2型感染内皮细胞条件培养基对上皮细胞愈合的影响：活细胞成像分析 | Hincapie, V. | N/A | Effect of inactivated conditioned media from DENV-2-infected endothelial cells on epithelial cell healing: live cell imaging analysis. | |
| 代谢重编程通过稳定干扰素-γ诱导的IRF1来影响痘病毒感染的结果 | Chang, T. | N/A | Metabolic reprogramming tips vaccinia virus infection outcomes by stabilizing interferon-g induced IRF1 | |
| 元基因组覆盖率的差异可能会混淆基于丰度和多样性的结论。 | Riquelme, B. A. | N/A | Differences in metagenome coverage may confound abundance-based and diversity conclusions | |
| 鼻内递送一种广泛中和的单域抗体，靶向ACE2，可预防SARS-CoV-2感染。 | Blachier, S. | N/A | Intranasal delivery of a broadly neutralizing single domain antibody targeting ACE2 protects against SARS-CoV-2 infection | |
| 新型转基因人源化α-1抗胰蛋白酶缺乏症小鼠模型，基于小鼠SERPINA1基因敲除背景 | Oshins, R. | N/A | Novel Transgenic Humanized Alpha-1 Antitrypsin Deficiency Mouse Model on Murine SERPINA1 Null Background | |
| 从Haloferax volcanii中删除前病毒会影响运动性、抗逆性和CRISPR RNA的表达。 | Di Cianni, N. | N/A | Provirus deletion from Haloferax volcanii affects motility, stress resistance and CRISPR RNA expression | |
| RPS19 和 RPL5，钻石黑人贫血症中最常见的突变基因，影响DNA双链断裂修复。 | DeCleene, N. F. | N/A | RPS19 and RPL5, the most commonly mutated genes in Diamond Blackfan anemia, impact DNA double-strand break repair | |
| 鉴定单性生殖和雌雄同体海洋鱼类中性二型循环微小RNA。 | Geffroy, B. | N/A | Identifying sexually dimorphic circulating microRNAs in gonochoristic and hermaphroditic marine fish species. | |
| RAD51同源物与RAD51同源物复合物BCDX2和CX3与BRCA2相互作用 | Thrasher, J. G. | N/A | RAD51 Paralogs and RAD51 Paralog Complexes BCDX2 and CX3 Interact with BRCA2 | |
| SMYD5是一种核糖体甲基转移酶，通过识别KXY基序，对RPL40赖氨酸22进行三甲基化修饰。 | Hamey, J. J. | N/A | SMYD5 is a ribosomal methyltransferase which trimethylates RPL40 lysine 22 through recognition of a KXY motif | |
| 果蝇（Drosophila melanogaster）中对异硫氰酸酯敏感的气味受体及其在食草性近缘物种中的进化扩张 | Matsunaga, T. | N/A | Odorant receptors tuned to isothiocyanates in Drosophila melanogaster and their evolutionary expansion in herbivorous relatives | |
| 一组针对果蝇中保守信号配体的分裂Gal4驱动器 | Ewen-Campen, B. | N/A | A collection of split-Gal4 drivers targeting conserved signaling ligands in Drosophila | |
| 斑马鱼中rbfox1功能丧失导致bdnf/trkb2和pac1a表达失调，进而引起HPI轴过度激活、应激反应改变以及稳态负荷过重。 | Leggieri, A. | N/A | rbfox1 loss of function in zebrafish leads to dysregulation in bdnf/trkb2 and pac1a expression resulting in HPI axis hyperactivation, altered stress response and allostatic overload | |
| CREB3功能获得性变异可预防ALS | Megat, S. | N/A | CREB3 gain of function variants protect against ALS | |
| 在“狗衰老项目”中，来自多样化犬群的DNA甲基化模式揭示了年龄差异。 | Mariner, B. L. | N/A | DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project | |
| 近北极地区的蝙蝠（Myotis bats）具有广泛的寿命和由DNA病毒驱动的适应性。 | Vazquez, J. M. | N/A | Extensive longevity and DNA virus-driven adaptation in nearctic Myotis bats | |
| 磷酸蛋白质组学揭示了成纤维细胞在炎症刺激下复杂的资源管理机制 | Janker-Bortel, P. | N/A | Phosphoproteomics highlights complex resource management upon inflammatory stimulation of fibroblasts | |
| 扭转性创伤性视神经病变（TITON）：一种生理上相关的创伤性视神经病变动物模型 | Ryan, A. K. | N/A | Torsion-Induced Traumatic Optic Neuropathy (TITON): A Physiologically Relevant Animal Model of Traumatic Optic Neuropathy | |
| 通过功能引导的计算机模拟进化将AAV衣壳序列映射到功能 | Zheng, H. | N/A | Mapping AAV capsid sequences to functions through function-guided in silico evolution | |
| 深度学习助力在Pharos中发现激酶药物靶点 | Halasz, A. M. | N/A | Deep Learning enabled discovery of kinase drug targets in Pharos | |
| 探索Corallococcus属的代谢潜力：丰富的次生代谢产物和CAZymes来源 | Hossain, M. S. | N/A | Exploration of the Metabolic Potential of the Corallococcus Genus: A Rich Source of Secondary Metabolites, and CAZymes | |
| GATA1缺陷型人类多能干细胞生成的嗜中性粒细胞具有增强的抗真菌免疫能力，这种免疫能力是通过整合素CD18介导的。 | Wagner, A. S. | N/A | GATA1-deficient human pluripotent stem cells generate neutrophils with improved antifungal immunity that is mediated by the integrin CD18 | |
| 在低pH、低温及高渗透压应激条件下，大肠杆菌的生长需要wzxE翻转酶来处理肠杆菌共同抗原中间体。 | Yamaguchi, S. | N/A | Escherichia coli growth under low pH, low temperature, and high osmotic stress conditions requires the wzxE flippase for the enterobacterial common antigen intermediate | |
| 系统性、高通量地表征噬菌体基因在不同宿主中的必需性 | Chen, J. | N/A | Systematic, high-throughput characterization of bacteriophage gene essentiality on diverse hosts | |
| 火疫病菌欧文氏菌通过苹果叶自然脱落的毛状体伤口进入叶片。 | Millett, F. | N/A | The fire blight pathogen Erwinia amylovora enters apple leaves through naturally-occurring wounds from the abscission of trichomes | |
| 多聚腺苷酸化酶PAPI是致病菌中维持毒力质粒所必需的 | Schubert, K. | N/A | The polyadenylase PAPI is required for virulence plasmid maintenance in pathogenic bacteria | |
| 一种用于倾斜系列数据相干功率谱平均以改进CTF估计的方法 | Khavnekar, S. | N/A | An approach for coherent periodogram averaging of tilt-series data for improved CTF estimation | |
| 质粒DNA中的人源Fos启动子活性过高 | Gorbunov, A. | N/A | Isolated human Fos promoter in plasmid DNA is overactive | |
| # BioRxiv 2024-10-10 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 多切片空间转录组学数据在二维和三维中的自动化整合 | Bienroth, D. | N/A | Automated Integration of Multi-Slice Spatial Transcriptomics Data in 2D and 3D | |
| 倒位可以积累平衡的性对抗：来自模拟和果蝇实验的证据 | McAllester, C. S. | N/A | Inversions Can Accumulate Balanced Sexual Antagonism: Evidence from Simulations and Drosophila Experiments | |
| 冬眠会减少脑干中的GABA信号传导，以增强在低温下的呼吸运动活动。 | Saunders, S. E. | N/A | Hibernation reduces GABA signaling in the brainstem to enhance motor activity of breathing at cool temperatures | |
| 表观遗传的细胞可塑性遗传性通过一对多的基因型到表型映射驱动了癌症药物的抗性。 | Fernandez-Mateos, J. | N/A | Epigenetic heritability of cell plasticity drives cancer drug resistance through one-to-many genotype to phenotype mapping | |
| TML1与TML2协同调控苜蓿根瘤形成并影响丛枝菌根共生 | Chaulagain, D. | N/A | TML1 AND TML2 SYNERGISTICALLY REGULATE NODULATION AND AFFECT ARBUSCULAR MYCORRHIZA IN MEDICAGO TRUNCATULA | |
| 临床批准的BTK抑制剂对全长BTK构象的影响及慢性淋巴细胞白血病中BTK耐药突变的发展分析。 | Joseph, R. E. | N/A | Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia. | |
| 用于从纳米孔直接RNA测序数据估计RNA修饰的原始信号分割 | Cheng, G. | N/A | Raw signal segmentation for estimating RNA modification from Nanopore direct RNA sequencing data | |
| 一种新型人多能干细胞基因激活系统鉴定出IGFBP2为体外造血祖细胞生成的中介因子 | Petazzi, P. | N/A | A novel human pluripotent stem cell-based gene activation system identifies IGFBP2 as a mediator in the production of hematopoietic progenitors in vitro | |
| 时间尺度与遗传连锁解释了防御系统对横向基因转移影响的可变性 | Liu, Y. | N/A | Timescales and genetic linkage explain the variable impact of defense systems on horizontal gene transfer | |
| 实蝇科中的嗅觉：检测与辨别之间的平衡 | Ramiaranjatovo, G. | N/A | Olfaction in Tephritidae: a balance between detection and discrimination | |
| 蛋白质组动态揭示Leiomodin 1是肌源性分化的关键调控因子 | Spath, E. | N/A | Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation | |
| Ais：简化冷冻电子断层扫描数据集的分割流程 | Last, M. G. F. | N/A | Ais: streamlining segmentation of cryo-electron tomography datasets | |
| WENDY：基于协方差动态的基因调控网络推断 | Wang, Y. | N/A | WENDY: Covariance Dynamics Based Gene Regulatory Network Inference | |
| 在小鼠新皮质中，对局部创伤性脑损伤的大规模和细胞反应的成像 | Bibineyshvili, Y. | N/A | Imaging the large-scale and cellular response to focal traumatic brain injury in mouse neocortex | |
| 通过顺式调控机制靶向三阴性乳腺癌中的昼夜节律转录程序 | Pan, Y. | N/A | Targeting circadian transcriptional programs in triple negative breast cancer through a cis-regulatory mechanism | |
| 从C3向C4光合作用进化的过程是由 | Yongyao, Z. | N/A | The process that the evolution from C3 towards C4 photosynthesis is driven | |
| 同源自然杀伤细胞疗法激活了转移肺中的树突状细胞和T细胞，并有效治疗了低负荷的转移病灶。 | Huang, S.-W. | N/A | Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases | |
| 环境与环境之间的相互作用（ExE）在不同的遗传背景下（ExExG）有所不同。 | Schmidlin, K. | N/A | Environment by environment interactions (ExE) differ across genetic backgrounds (ExExG) | |
| Piximi - 一个用于生物图像及更广泛领域的图像发现网络工具 | Moser, L. M. | N/A | Piximi - An Images to Discovery web tool for bioimages and beyond | |
| 有效的抗肿瘤免疫反应是由免疫细胞合作网络所调控的，该网络通过组织稳态通路发挥作用，而非直接的细胞毒性作用。 | Koelsch, N. | N/A | Effective anti-tumor immune responses are orchestrated by immune cell partnership network that functions through tissue homeostatic pathways, not direct cytotoxicity | |
| 通过动态力学刺激增强细胞质中外源mRNA的表达 | Chen, J. | N/A | Enhancing Cytoplasmic Expression of Exogenous mRNA through Dynamic Mechanical Stimulation | |
| 染色质内源性切割提供了一种对酵母RNA聚合酶II转录动力学的全局视角。 | VanBelzen, J. | N/A | Chromatin endogenous cleavage provides a global view of yeast RNA polymerase II transcription kinetics | |
| 探索不同处理对受橄榄疫霉（Phytophthora oleae）影响的橄榄（Olea europaea L.）果实基因表达的影响：基于RNA测序的转录组分析的见解。 | Conti Taguali, S. | N/A | Exploring the Impact of Various Treatments on Gene Expression in Olive (Olea europaea L.) Drupes Affected by Phytophthora oleae: Insights from RNA sequencing-based transcriptome analysis. | |
| 时间动态分析揭示，同时进行的工作记忆负荷通过破坏刺激-反应映射消除了斯特鲁普效应。 | Li, Y. | N/A | Temporal dynamics analysis reveals that concurrent working memory load eliminates the Stroop effect through disrupting stimulus-response mapping | |
| 质粒病毒维持使细菌种群从感染中恢复，并实现病毒与细菌的共存。 | Sanchez-Martinez, R. | N/A | Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence | |
| 预测动态控制精确绘制了2,3-丁二醇生产的设计空间 | Gotsmy, M. | N/A | Predictive Dynamic Control Accurately Maps the Design Space for 2,3-Butanediol Production | |
| SpinalTRAQ：一种新颖的颈椎脊髓体积图谱，用于识别健康和卒中后小鼠的皮质脊髓束突触投射体 | Poinsatte, K. | N/A | SpinalTRAQ: A novel volumetric cervical spinal cord atlas identifies the corticospinal tract synaptic projectome in healthy and post-stroke mice | |
| 利用扩增子测序技术将微生物群落结构与功能联系起来：基于干旱胁迫下与小麦根系相关的NRPS基因的研究 | Guan, Y. | N/A | Linking microbial community structure with function using amplicon sequencing of the NRPS genes associated with wheat roots under drought stress | |
| SARS-CoV-2主蛋白酶活性位点环的构象空间由配体结合和蛋白质间别构效应决定。 | Lee, E. | N/A | The Conformational Space of the SARS-CoV-2 Main Protease Active Site Loops is Determined by Ligand Binding and Interprotomer Allostery | |
| 从基因到模式：一个建模胚胎发育从转录调控中涌现的框架 | Garcia-Guillen, J. | N/A | From Genes to Patterns: A Framework for Modeling the Emergence of Embryonic Development from Transcriptional Regulation | |
| 在裂殖酵母中，细胞质内的扩散随着细胞大小的增加而增加。 | Tan, C. | N/A | Intracellular diffusion in the cytoplasm increases with cell size in fission yeast | |
| 慢性使用氟西汀会下调前额叶皮质中小清蛋白中间神经元的线粒体活性。 | Jetsonen, E. | N/A | Chronic treatment with fluoxetine downregulates mitochondrial activity in parvalbumin interneurons of prefrontal cortex | |
| ALG-1，一种microRNA的Argonaute蛋白，促进秀丽隐杆线虫的生殖器诱导。 | Zhen, S. | N/A | ALG-1, a microRNA argonaute, promotes vulva induction in C. elegans | |
| 钾通道模拟中的电荷缩放：电导、离子占据、电压响应与选择性 | Hui, C. | N/A | Charge Scaling in Potassium Channel Simulations: Conductance, Ion Occupancy, Voltage Response, and Selectivity | |
| 新型烈性噬菌体对小鼠鲍曼不动杆菌急性肺部感染的疗效与安全性 | Wang, J. | N/A | Efficacy and Safety of a novel virulent phage against acute pulmonary infection of Acinetobacter baumanniii in mice | |
| 基于多组分硫内酯的可电离脂质筛选平台，用于高效且可调节的mRNA向肺部的递送 | Pena, A. | N/A | Multicomponent Thiolactone-Based Ionizable Lipid Screening Platform for an Efficient and Tunable mRNA Delivery to the Lungs | |
| 18q的缺失改变了TGFβ信号传导，影响了人胚胎干细胞的前后神经外胚层命运 | Lei, Y. | N/A | Loss of 18q alters TGFβ signalling affecting anteroposterior neuroectodermal fate in human embryonic stem cells | |
| TRIM37利用肽基序识别和底物依赖性寡聚化来防止异常的纺锤体极组装。 | Bellaart, A. | N/A | TRIM37 employs peptide motif recognition and substrate-dependent oligomerization to prevent ectopic spindle pole assembly | |
| TOMM40-APOE嵌合体关联阿尔茨海默病最高风险基因：线粒体调控与APOE4发病机制的新途径 | Xu, J. | N/A | TOMM40-APOE chimera linking Alzheimer's highest risk genes: a new pathway for mitochondria regulation and APOE4 pathogenesis | |
| 在果蝇癌细胞模型中，细胞集体脱层的方向性受组织结构和细胞粘附的调控。 | MIRA OSUNA, M. | N/A | The directionality of collective cell delamination is governed by tissue architecture and cell adhesion in a Drosophila carcinoma model | |
| EPHA2在食管发育过程中调控SOX2 | Li, T. | N/A | EPHA2 Regulates SOX2 during Esophageal Development | |
| 失去青鳉鱼cGAS/STING功能减轻了细胞衰老和与年龄相关的特征，但并未延长生物体的寿命。 | Ballhysa, E. | N/A | Loss of killifish cGAS/STING function attenuates cellular senescence and age-related signatures but does not extend organismal life span | |
| 增强型RNA靶向CRISPR-Cas技术在斑马鱼中的应用 | Moreno-Sanchez, I. | N/A | Enhanced RNA-targeting CRISPR-Cas technology in zebrafish | |
| 儿童呼吸道病毒感染的局部和全身免疫反应的蛋白质组学分析 | Lydon, E. | N/A | Proteomic profiling of the local and systemic immune response to pediatric respiratory viral infections | |
| assessPool: 一个用于群体基因组分析的灵活管道，适用于合并测序数据 | Freel, E. B. | N/A | assessPool: a fexible pipeline for population genomic analyses of pooled sequencing data | |
| 亚热带和热带植物物种独特的地下生态策略拓展了根系特征空间 | Guerrero Ramirez, N. R. | N/A | Unique belowground ecological strategies of subtropical and tropical plant species expand the root trait space | |
| 农业集约化导致的遗传多样性丧失和遗传负荷积累的物种特异性 | Nolen, Z. J. | N/A | Species-specific loss of genetic diversity and accumulation of genetic load following agricultural intensification | |
| 注射型Janus基底纳米矩阵（JBNm）在维持再生软骨长期体内平衡中的作用，适用于组织芯片应用 | Yau, A. | N/A | Injectable Janus Base Nanomatrix (JBNm) in Maintaining Long-Term Homeostasis of Regenerated Cartilage for Tissue Chip Applications | |
| 使用环保溶剂增强光交联丝素蛋白的多功能性 | Brooks, A. K. | N/A | Enhancing the versatility of photocrosslinkable silk fibroin using an eco-friendly solvent | |
| 人子宫组织电活动的有限元建模：模拟技术的进展 | Zahran, S. | N/A | Finite Element Modeling of Electrical Activity in Human Uterine Tissue: Advances in Simulation Techniques | |
| 从非靶向代谢组学数据中直接经验性地建立药物暴露记录 | Zhao, H. N. | N/A | Empirically establishing drug exposure records directly from untargeted metabolomics data | |
| 工程化年龄模拟乳腺癌模型揭示了年轻和衰老微环境中药物反应的差异 | Yang, J. | N/A | Engineered Age-Mimetic Breast Cancer Models Reveal Differential Drug Responses in Young and Aged Microenvironments | |
| 利用MORFEE增强小ORF改变变异的注释：引入MORFEEdb，一个全面的人类5'UTR上游ORF受影响SNV目录 | Meguerditchian, C. | N/A | Enhancing the annotation of small ORF-altering variants using MORFEE: introducing MORFEEdb, a comprehensive catalog of SNVs affecting upstream ORFs in human 5'UTRs | |
| 生物信息学分析表明，表皮葡萄球菌（Staphylococcus epidermidis）的SE_1780蛋白可能是脂肪酶Fph家族的成员。 | Qaddourah, M. | N/A | Bioinformatics Analysis Suggests That SE_1780 protein from Staphylococcus epidermidis may be a member of the Fph Family of Lipases | |
| 蛋白质结构预测的终结：通过窗口化多序列比对提高嵌合蛋白质的预测准确性 | Vedula, S. | N/A | The end of protein structure prediction: Improving prediction accuracy in chimeric proteins by windowed multiple sequence alignment | |
| James-Stein估计器提高了人体运动学和代谢数据中的准确性和样本效率。 | Alwan, A. | N/A | James-Stein estimator improves accuracy and sample efficiency in human kinematic and metabolic data | |
| 假单胞菌属内竞争决定了共生体在拟南芥中的保护功能 | Amrhein, A. | N/A | Pseudomonas intra-genus competition determines protective function of SynComs in Arabidopsis thaliana | |
| 拟南芥莽草酸途径中的3-脱氧-D-阿拉伯糖-庚酮糖酸-7-磷酸（DAHP）合酶表现出依赖锰和钴的活性。 | Yokoyama, R. | N/A | Arabidopsis 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthases of the shikimate pathway display both manganese- and cobalt-dependent activities | |
| 低强度聚焦超声神经调节揭示了丘脑在意识知觉中的作用 | Jang, H. | N/A | Thalamic Roles in Conscious Perception Revealed by Low-Intensity Focused Ultrasound Neuromodulation | |
| 感知和图像记忆中的时间动态和读出延迟 | Matic, K. | N/A | Temporal dynamics and readout latency in perception and iconic memory | |
| 深海鱼类揭示了脊椎动物视觉发育的替代途径 | Fogg, L. G. | N/A | Deep-sea fish reveal alternative pathway for vertebrate visual development | |
| 通过细胞膜蛋白工程改造脂质体以破坏黑素小体转移 | Liu, C. | N/A | Engineering liposomes with cell membrane proteins to disrupt melanosome transfer | |
| 在计算机模拟中，胶原蛋白-IV网络的非平衡重塑 | Meadowcroft, B. | N/A | Non-equilibrium remodelling of collagen-IV networks in silico | |
| 硅和生物玻璃纳米材料在类髓质活体材料中的评估 | Mbitta Akoa, D. | N/A | Evaluation of Silica and Bioglass Nanomaterials in Pulp-Like Living Materials | |
| 哈弗氏管内骨小梁的矿化程度取决于哈弗氏管的形成位置 | Cantamessa, A. | N/A | The mineralization of osteonal cement line depends on where the osteon is formed | |
| 一种水动力天线：蝠鲼尾部的新型侧线系统 | Cerda, J. C. | N/A | A hydrodynamic antenna: novel lateral line system in the tail of myliobatid stingrays | |
| 大规模饲养食用昆虫Gryllodes sigillatus（直翅目：蟋蟀科）的生长、发育及生活史 | Kong, J. D. | N/A | Growth, development, and life history of a mass-reared edible insect, Gryllodes sigillatus (Orthoptera: Gryllidae) | |
| 使用SNAP标签对Munc13-1进行内源性标记，作为监测突触纳米结构的工具 | Kowald, M. | N/A | Endogenous tagging of Munc13-1 with a SNAP tag as a tool for monitoring synapse nanoarchitecture | |
| 序列学习中的声音与景象：辅助听觉提示能否提升运动任务表现？ | Leow, L.-A. | N/A | Sounds and Sights in Sequence Learning: Can Accessory Auditory Cues Enhance Motor Task Performance? | |
| 半胱氨酸蛋白酶抑制剂E-64的生物合成特性及组合生物催化研究 | Liu, M. | N/A | Biosynthetic characterization and combinatorial biocatalysis of the cysteine protease inhibitor E-64 | |
| 体外转录RNA的化学环化为环状mRNA设计开辟了新的途径 | Mamot, A. | N/A | Chemical circularization of in vitro transcribed RNA opens new avenues for circular mRNA design | |
| 对选择性和双重拮抗EP2和EP4前列腺素受体的结构洞察 | Wu, Y. | N/A | Structural Insights into Selective and Dual Antagonism of EP2 and EP4 Prostaglandin Receptors | |
| 利用GSMMs和多组学方法改进基于HEK293的AAV生产 | Zehetner, L. | N/A | Improving HEK293-based AAV-production using GSMMs, and a multi-omics approach | |
| 通过环挤出介导的刚性可以在全局范围内有序细菌染色体 | Harju, J. | N/A | Loop-extruder mediated rigidity can globally order bacterial chromosomes | |
| 高吞吐量根癌农杆菌介导的植物转化半自动化工作流程 | Annese, D. | N/A | Semi-automated workflow for high-throughput Agrobacterium-mediated plant transformation | |
| 球形细胞：改变硅藻DNA传递的游戏规则 | Walker, E. J. L. | N/A | Spheroplasted cells: a game changer for DNA delivery to diatoms | |
| 深度突变扫描识别出能够提高II型-A CRISPR-Cas系统中间隔序列获取的Cas1和Cas2变体 | Hofmann, R. | N/A | Deep mutational scanning identifies variants of Cas1 and Cas2 that increase spacer acquisition in type II-A CRISPR-Cas systems | |
| 通过冷冻电镜分析揭示的二元毒素孔道逐步成熟机制 | Yamada, T. | N/A | Step-by-Step Maturation Mechanism of Binary Toxin Pore Revealed by Cryo-EM Analysis | |
| 双链DNA减少了唾液中dsRNA的降解，并显著增强了RNAi介导的Halyomorpha halys基因沉默效果。 | Amineni, V. P. S. | N/A | Double-stranded DNA reduces dsRNA degradation in the saliva and significantly enhanced RNAi-mediated gene silencing in Halyomorpha halys | |
| 芒果苷作为甲状腺素纤维化潜在抑制剂的研究 | Grudinina, N. | N/A | MANGIFERIN AS A POTENTIAL INHIBITOR OF TRANSTHYRETIN FIBRILOGENESIS | |
| 肿瘤抑制性miR-317和长链非编码RNA Peony源自一个多顺反子非编码RNA位点，该位点调控生殖系分化和睾丸形态。 | Carney, T. D. | N/A | Tumor suppressor miR-317 and lncRNA Peony are expressed from a polycistronic non-coding RNA locus that regulates germline differentiation and testis morphology | |
| CCG中断在DM1患者中不稳定且呈现高甲基化状态。 | Lameiras, S. | N/A | CCG interruptions are unstable and hypermethylated in DM1 patients | |
| 两种人群中抗锥虫突变的新发率 | Melamed, D. | N/A | De novo rates of a Trypanosoma-resistant mutation in two human populations | |
| 记者CRISPR筛选揭示了Xist位点的顺式和反式调控原理 | Schwaemmle, T. | N/A | Reporter CRISPR screens decipher cis- and trans-regulatory principles at the Xist locus | |
| 鉴定拟南芥当地自然种群中存在的一种花粉杀手的相关新基因 | Ricou, A. | N/A | Identification of novel genes responsible for a pollen killer present in local natural populations of Arabidopsis thaliana | |
| CRISPR 平铺缺失筛选揭示了神经精神风险基因的功能增强子和转录的等位补偿效应（ACE） | Ren, X. | N/A | CRISPR tiling deletion screens reveal functional enhancers of neuropsychiatric risk genes and allelic compensation effects (ACE) on transcription | |
| 通过邻近条形码测序同时映射多种RNA修饰 | Sendinc, E. | N/A | Mapping multiple RNA modifications simultaneously by proximity barcode sequencing | |
| 小鼠着丝粒和副着丝粒的基因组和表观基因组图谱 | Chaudhry, G. | N/A | Genomic and epigenomic maps of mouse centromeres and pericentromeres | |
| 在荷兰一座城市植物园的Asparagales植物中发现了新的和变种的马铃薯Y病毒 | Dekker, R. J. | N/A | Discovery of new and variant Potyviruses in Asparagales plants from a Dutch urban botanic garden | |
| 心磷脂缺乏会破坏辅酶Q的氧化还原状态并引发脂肪性肝炎 | Brothwell, M. J. | N/A | Cardiolipin deficiency disrupts CoQ redox state and induces steatohepatitis | |
| 通过SpyTag硫酰胺取代调节SpyCatcher连接动力学 | Fiore, K. | N/A | Modulation of SpyCatcher Ligation Kinetics by SpyTag Thioamide Substitution | |
| 2.6-A分辨率的冷冻电镜结构显示了Ia类核糖核苷酸还原酶与基于机制的抑制剂N3CDP结合的复合物 | Westmoreland, D. E. | N/A | 2.6-A resolution cryo-EM structure of a class Ia ribonucleotide reductase trapped with mechanism-based inhibitor N3CDP | |
| DNA聚合酶在压力下锁定复制叉 | Jia, X. | N/A | DNA Polymerase Locks Replication Fork Under Stress | |
| SIRT7与核小体结合及其底物特异性的结构基础 | Moreno Yruela, C. | N/A | Structural basis of SIRT7 nucleosome engagement and substrate specificity | |
| 圆环DNA的扭转力学 | Singh, G. | N/A | Torsional Mechanics of Circular DNA | |
| Sanfetrinem是一种口服的β-内酰胺抗生素，被重新用于结核病的治疗。 | Ramon-Garcia, S. | N/A | Sanfetrinem, an oral beta-lactam antibiotic repurposed for the treatment of tuberculosis | |
| 杂合和广谱的MxA超级限制因子克服了抗病毒限制中的广度特异性权衡 | Geiger, R. A. | N/A | Heterozygous and generalist MxA super-restrictors overcome breadth-specificity tradeoffs in antiviral restriction | |
| 核心微生物组的系统发育测量 | Bewick, S. A. | N/A | Phylogenetic Measures of the Core Microbiome | |
| 绣球属植物天然甜味剂生物合成途径的解析与功能鉴定 | Padmakumar Sarala, G. | N/A | Elucidation and functional characterization of natural sweetener biosynthesis in hortensia species | |
| 寄生线虫Heligmosomoides bakeri中机会性吸血行为的证据 | Szabo, E. K. | N/A | Evidence of opportunistic blood feeding in the parasitic nematode Heligmosomoides bakeri | |
| 在人类照料下的一种极度濒危的两栖动物中，精子质量指标表现出年度波动。 | Julien, A. R. | N/A | Sperm quality metrics exhibit annual fluctuations in a critically endangered amphibian managed under human care | |
| 自然干扰和连通性塑造了欧洲水生大型无脊椎动物群落季节性变化的格局 | Chalmandrier, L. | N/A | Natural disturbances and connectivity shape the seasonal variability of aquatic macroinvertebrate communities across Europe | |
| # BioRxiv 2024-10-08 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| BEdeepon：一种用于预测碱基编辑效率和结果的计算机工具 | Zhang, C. | N/A | BEdeepon: an in silico tool for prediction of base editor efficiencies and outcomes | |
| 受生物物理启发的神经元群体平均场模型，由离子交换机制驱动 | Rabuffo, G. | N/A | Biophysically inspired mean-field model of neuronal populations driven by ion exchange mechanisms | |
| 从初始形成到发展性精炼：GABA能输入塑造初级体感皮层中的神经元子网络 | Huang, J.-Y. | N/A | From Initial Formation to Developmental Refinement: GABAergic Inputs Shape Neuronal Subnetworks in the Primary Somatosensory Cortex | |
| 对蓝钟虫前后mRNA区域化的全基因组分析揭示了微管细胞骨架的作用 | Albright, A. R. | N/A | Genome-wide analysis of anterior-posterior mRNA regionalization in Stentor coeruleus reveals a role for the microtubule cytoskeleton | |
| 采用理性方法对抗体序列进行预训练 | Gao, X. | N/A | Pre-training with a rational approach for antibody sequence representation | |
| 同一感知决策任务的多种脑激活模式 | Nakuci, J. | N/A | Multiple Brain Activation Patterns for the Same Perceptual Decision-Making Task | |
| 饱腹激素胆囊收缩素通过调控促性腺激素分泌，在鱼类中调控生殖过程。 | Hollander cohen, L. | N/A | The satiety hormone cholecystokinin gates reproduction in fish by controlling gonadotropin secretion | |
| 新的纯化方法揭示酵母和人类应激颗粒核心是具有复杂转录组和蛋白质组的离散颗粒 | Demeshkina, N. A. | N/A | New purifications reveal yeast and human stress granule cores are discrete particles with complex transcriptomes and proteomes | |
| 人类ADA2缺乏症的特点是缺乏细胞内低糖基化的腺苷脱氨酶2形式。 | Ehlers, L. | N/A | Human ADA2 deficiency is characterized by the absence of an intracellular hypoglycosylated form of adenosine deaminase 2 | |
| 通过干扰主调控bHLH异二聚体，利用ACT样域进行化学抑制气孔分化 | Nakagawa, A. | N/A | Chemical inhibition of stomatal differentiation by perturbation of the master-regulatory bHLH heterodimer via an ACT-Like domain | |
| 新型神经启发式控制器通过内部模型在低级肢体任务中实现了模块化泛化 | Munoz, D. | N/A | New neural-inspired controller generalises modularity over lower limb tasks through internal models | |
| 酵母中的单细胞eQTL定位揭示了生长与繁殖之间的权衡 | Boocock, J. | N/A | Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction | |
| 质膜孔作为非传统的膜接触位点，在植物细胞间的分子交换中起着调节作用。 | Smokvarska, M. | N/A | Plasmodesmata act as unconventional membrane contact sites regulating inter-cellular molecular exchange in plants | |
| 评估大型多模态模型在生物医学图像分类中的一步学习能力和可解释性 | Hou, W. | N/A | Assessing large multimodal models for one-shot learning and interpretability in biomedical image classification | |
| 神经发育障碍相关TRIO变异的杂合性在行为、神经发育和突触传递方面导致小鼠出现不同的缺陷。 | Ishchenko, Y. | N/A | Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice | |
| 预期情绪与学业表现：在实习教师实验室体验中无聊的作用 | Ochoa de Alda, J. A. G. | N/A | Anticipatory Emotions and Academic Performance: The Role of Boredom in a Preservice Teachers' Lab Experience | |
| 小鼠树突靶向中间神经元中的超线性树突整合 | Griesius, S. | N/A | Supralinear dendritic integration in murine dendrite-targeting interneurons | |
| 基于高维数据的生态学与进化可解释性和预测性模型 | Jahner, J. P. | N/A | Interpretable and predictive models based on high-dimensional data in ecology and evolution | |
| 神经元中Ptbp1的碱基编辑减轻了帕金森病小鼠模型的症状 | Boeck, D. | N/A | Base editing of Ptbp1 in neurons alleviates symptoms in a mouse model for Parkinson's disease | |
| 释放Krakencoder：一种统一的脑连接组翻译和融合工具 | Jamison, K. W. | N/A | Release the Krakencoder: A unified brain connectome translation and fusion tool | |
| 单细胞中核糖体含量的异质性及其对生长规律的影响 | Brettner, L. M. | N/A | Single-cell heterogeneity in ribosome content and the consequences for the growth laws | |
| 评估泛基因组图谱上的基因组保守性——基于PanSel的方法 | Zytnicki, M. | N/A | Assessing genome conservation on pangenome graphs with PanSel | |
| 对短语结构和主语岛违例敏感的皮层网络 | Matchin, W. | N/A | Cortical networks responsive to phrase structure and subject island violations | |
| 利用光遗传学工具在Neuro2a细胞中诱导应激颗粒和稳定的tau聚集。 | Sakuragi, S. | N/A | Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool. | |
| 预测持续注意力的功能脑网络并不特定于感知模态 | Corriveau, A. | N/A | Functional brain networks predicting sustained attention are not specific to perceptual modality | |
| CLEAN-Contact：基于对比学习的酶功能注释预测与结构推断 | Yang, Y. | N/A | CLEAN-Contact: Contrastive Learning-enabled Enzyme Functional Annotation Prediction with Structural Inference | |
| 将心磷脂结合到人工膜蛋白上揭示了脂质介导稳定性的决定因素 | Abramsson, M. L. | N/A | Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization | |
| 外部微生物群通过卵壳与正在发育的斑马鱼（Danio rerio）胚胎进行交流，并影响其发育轨迹。 | Green, E. M. | N/A | The External Microbiome Communicates with the Developing Zebrafish (Danio rerio) Embryo Through the Chorion and Influences Developmental Trajectory | |
| 齿状回中功能失调的S1P/S1PR1信号传导驱动了慢性疼痛相关记忆障碍的易感性 | Cui, M. | N/A | Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment | |
| BIT：基于表观基因组学查询区域集的转录调控因子贝叶斯识别 | Lu, Z. | N/A | BIT: Bayesian Identification of Transcriptional Regulators from Epigenomics-Based Query Region Sets | |
| 揭示亲炎性巨噬细胞在子痫前期母胎界面免疫网络失衡中的关键作用 | Fei, H. | N/A | Unveiling the Crucial Role of Pro-inflammatory Macrophages in the Immune Network Imbalance of the maternal-fetal interface with Preeclampsia | |
| 单细胞和空间转录组学分析揭示了心肌梗死后心肌淋巴管生成的动态转录特征 | He, J. | N/A | Single-Cell and Spatial Transcriptomic Analyses Reveals the Dynamic Transcript Profiles of Myocardial Lymphangiogenesis post Myocardial Infarction | |
| 听觉皮层中协同调谐的神经元集合活动的快速再平衡 | Kang, H. | N/A | Rapid rebalancing of co-tuned ensemble activity in the auditory cortex | |
| scCancerExplorer：一个综合数据库，用于交互式探索人类泛癌单细胞多组学数据 | Huang, C. | N/A | scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer | |
| 巨型转座子促进主要真菌病原体中的菌株异质性 | Gluck-Thaler, E. | N/A | Giant transposons promote strain heterogeneity in a major fungal pathogen | |
| 基于注意力的前额-后部耦合在人类大脑视觉意识中的作用 | Zhang, X. | N/A | Attention-based frontal-posterior coupling for visual consciousness in the human brain | |
| 一个双组分信号决定了哪些锈菌分泌的蛋白质被转运到寄主植物的细胞中。 | Lawrence, G. J. | N/A | A two-component signature determines which rust fungi secreted proteins are translocated into the cells of the host plant | |
| 超越听觉中继：剖析下丘在感觉预测、奖励预测及认知决策中的作用 | Du, X. | N/A | Beyond Auditory Relay: Dissecting the Inferior Colliculus's Role in Sensory Prediction, Reward Prediction and Cognitive Decision-Making | |
| 降落在摇摆的栖木上：桃脸情侣鹦鹉偏爱极端 | Bhagavatula, P. S. | N/A | Landing on a swinging perch: peach-faced lovebirds prefer extremes | |
| 利用磷酸蛋白质组学解析卵母细胞减数分裂过程中的蛋白质磷酸化 | Peshkin, L. | N/A | Decoding protein phosphorylation during oocyte meiotic divisions using phosphoproteomics | |
| 通过血清素受体协同调节自发行为和时间积分全脑神经元活动 | Friedmann, D. | N/A | Concerted modulation of spontaneous behavior and time-integrated whole-brain neuronal activity by serotonin receptors | |
| 刺激编码塑造了触觉感知，并构成了自闭症中触觉感知的改变的基础。 | Semelidou, O. | N/A | Stimulus encoding shapes tactile perception and underlies alterations in autism. | |
| 与番茄黄曲叶病相关的菜豆金色花叶病毒在西地中海国家的人口变化 | Granier, M. | N/A | Population shifts in begomoviruses associated with tomato yellow leaf curl disease in western Mediterranean countries | |
| SAFARI：利用嘌呤/嘧啶编码进行古DNA的泛基因组比对 | Rubin, J. D. | N/A | SAFARI: Pangenome Alignment of Ancient DNA Using Purine/Pyrimidine Encodings | |
| 较低的非周期性活动与成年期言语流利性表现下降相关 | McKeown, D. J. | N/A | Lower Aperiodic Activity is Associated with Reduced Verbal Fluency Performance Across Adulthood | |
| 蓝细菌氮调节因子NtcA和PipX与DNA复合物的结构完全阐明了NtcA对DNA的结合以及PipX对RNA聚合酶的招募机制。 | Forcada-Nadal, A. | N/A | Structures of the cyanobacterial nitrogen regulators NtcA and PipX complexed to DNA fully clarify DNA binding by NtcA and recruitment of RNA polymerase by PipX | |
| 运动感知阿尔法和贝塔振荡在显性言语产生中的功能角色 | Huang, L. Z. | N/A | Functional Roles of Sensorimotor Alpha and Beta Oscillations in Overt Speech Production | |
| HHIP在表皮伤口愈合中的动态作用揭示了COPD易感性的潜在机制 | Deritei, D. | N/A | HHIP's Dynamic Role in Epithelial Wound Healing Reveals a Potential Mechanism of COPD Susceptibility | |
| 从视觉皮层活动动态估计注意场 | Bloem, I. M. | N/A | Dynamic estimation of the attentional field from visual cortical activity | |
| 辅助嗅球中的突触抑制调节信息素定位学习和记忆 | Marathe, S. D. | N/A | Synaptic inhibition in the accessory olfactory bulb regulates pheromone location learning and memory | |
| 一个涵盖5000年历史的考古牙结石数据集，用于古代人类口腔微生物组研究 | Standeven, F. J. | N/A | An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research | |
| 从头组装自私t超级基因揭示了有害的进化轨迹 | Runge, J.-N. | N/A | De novo assembly of the selfish t supergene reveals a deleterious evolutionary trajectory | |
| 撤回：新型神经启发式控制器通过内部模型在低肢任务中推广了模块化 | Munoz, D. | N/A | WITHDRAWN: New neural-inspired controller generalises modularity over lower limb tasks through internal models | |
| 分支肌动蛋白聚合推动侵入性突起的形成，以促进骨骼肌再生过程中肌纤维融合。 | Lu, Y. | N/A | Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration | |
| 长角甲虫利用磷酸钙生物矿物形成结构色 | Chang, Y. | N/A | Longhorn Beetles form Structural Colour Using Calcium Phosphate Biominerals | |
| 临床和分子变异特性对变异效应预测工具校准和性能的影响 | Isakov, O. | N/A | The Impact of Clinical and Molecular Variant Properties on Calibration and Performance of Variant Effect Prediction Tools | |
| 更多的细胞，高度多重单细胞数据中的更多双联体 | Howitt, G. | N/A | More cells, more doublets in highly multiplexed single-cell data | |
| 通过使用大肠杆菌作为模型微生物，区分纳米铜和离子铜的抗菌机制 | Jose, G. P. | N/A | Differentiating the mechanism of antibacterial activities of nano and ionic copper by using Escherichia coli as a model microorganism | |
| ADT-1004：一种口服生物可利用的选择性泛RAS抑制剂，用于胰腺导管腺癌 | Bandi, D. S. R. | N/A | ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma | |
| TGF-β介导的JunB-HBZ核转位是HTLV-1诱导白血病的关键驱动因素 | Zhang, W. | N/A | JunB-HBZ nuclear translocation by TGF-β is a key driver in HTLV-1-mediated leukemogenesis | |
| 计算设计一种用于全细胞生物转化的热稳定从头生物催化剂 | Elaily, W. | N/A | Computational design of a thermostable de novo biocatalyst for whole cell biotransformations | |
| 计算设计一种用于全细胞生物转化的热稳定从头生物催化剂 | Elaily, W. | N/A | Computational design of a thermostable de novo biocatalyst for whole cell biotransformations | |
| 在无序环境中范围扩展的元种群模型中的几何诱导竞争释放 | Nunez, J. G. | N/A | Geometry-induced competitive release in a meta-population model of range expansions in disordered environments | |
| 基因组报告：首次完成吸血猎蝽（Triatoma sanguisuga，Le Conte, 1855）的全基因组测序，该物种是恰加斯病的传播媒介 | Peterson, J. K. | N/A | Genome report: First whole genome sequence of Triatoma sanguisuga (Le Conte, 1855), vector of Chagas disease | |
| 厩螫蝇（双翅目，家蝇科）是多种家畜血液病原体的有效传播媒介。 | Muita, J. W. | N/A | Stomoxys flies (Diptera, Muscidae) are competent vectors of multiple livestock hemopathogens | |
| 植物基因型和微生物菌株组合对重金属胁迫条件下的转录组有显著影响 | Sharma, R. | N/A | Plant genotype and microbial strain combinations strongly influence the transcriptome under heavy metal stress conditions | |
| 预测西非关键生物多样性区域近期森林砍伐情况，以指导保护紧迫性 | Trew, B. T. | N/A | Predicting near-future deforestation in West African Key Biodiversity Areas to inform conservation urgency | |
| 免疫-病原体共进化中的信息处理自适应效率 | Bellamy, Q. N. | N/A | Adaptive efficiency of information processing in immune-pathogen co-evolution | |
| 海洋群岛进化辐射的生物地理学 | Baptiste, B. | N/A | The biogeography of evolutionary radiations on oceanic archipelagos | |
| 一种综合的全基因组方法，用于探索魏斯氏菌的益生潜力 | Hashem, A. | N/A | A Comprehensive Pangenome Approach to Exploring the Probiotic Potential of Weissella Confusa | |
| 苗圃和园艺中心作为外来植物入侵的中心 | Sonkoly, J. | N/A | Nurseries and garden centres as hubs of alien plant invasions | |
| 在高pH胁迫下豌豆根部的转录响应与微生物群落变化 | Thapa, A. | N/A | Transcriptional Responses and Microbiome Shifts in Pea Roots Under High pH Stress | |
| 核纤层蛋白A的心肌病突变扰乱了核纤层蛋白、核膜和染色质之间的相互作用，导致低液相分离（LLPS）。 | Nath, S. | N/A | Cardiomyopathic mutations of lamin A perturb mutual interactions of lamin, nuclear membrane, and chromatin leading to LLPS | |
| 评估几内亚比绍极度濒危的西部黑猩猩在时空上的有效种群大小：对保护管理的挑战与影响 | Ferreira da Silva, M. J. | N/A | Estimating the effective population size across space and time in the Critically Endangered western chimpanzee in Guinea-Bissau: challenges and implications for conservation management | |
| 基于压缩和k-mer的抗癌肽分析方法 | Ali, S. | N/A | Compression and k-mer based Approach For Anticancer Peptide Analysis | |
| 基于压缩和k-mer的抗癌肽分析方法 | Ali, S. | N/A | Compression and k-mer based Approach For Anticancer Peptide Analysis | |
| 早期生活行为表型与慈鲷鱼对常见实验室应激源的皮质醇反应 | Alvey, A. P. | N/A | Early Life Behavior Phenotypes and Cortisol Responses to Common Lab Stressors in a Cichlid Fish | |
| 人工智能对生物医学文献搜索的贡献：是革命性的还是复杂化的？ | Yip, R. | N/A | Artificial Intelligence's Contribution to Biomedical Literature Search: Revolutionizing or Complicating? | |
| 表达胆囊收缩素（Cholecystokinin）的GABA神经元在皮层抑制性突触中引发长期增强效应，并减弱声音-电击关联记忆。 | Zhang, G. | N/A | Cholecystokinin-expressing GABA neurons elicit long-term potentiation in the cortical inhibitory synapses and attenuate sound-shock associative memory | |
| 任务相关性在存在多个预测误差的情况下有选择性地调节感觉运动适应。 | Shingane, S. N. | N/A | Task relevance selectively modulates sensorimotor adaptation in the presence of multiple prediction errors. | |
| 用于共聚焦显微镜单个致密核心囊泡可视化的基因编码标记 | Yu, J. | N/A | Genetically-encoded markers for confocal visualization of single dense core vesicles | |
| 利用患者特异性iPSCs建模胸主动脉夹层揭示了血管平滑肌细胞功能障碍及细胞外基质失调 | Jin, P. | N/A | Modeling Thoracic Aortic Dissection Using Patient-Specific iPSCs Reveals VSMC Dysfunction and Extracellular Matrix Dysregulation | |
| 建模丙泊酚对脑活动的影响：来自计算脑电图研究的见解 | Zahran, S. | N/A | Modeling the Effects of Propofol on Brain Activity: Insights from Computational EEG Studies | |
| 自我扩增mRNA疫苗编码蛋白在肌肉和淋巴结中的差异清除率 | Kanechi, R. | N/A | Differential clearance rate of proteins encoded on a self-amplifying mRNA vaccine in muscle and lymph nodes | |
| 在热带木本豆科植物的根瘤中鉴定出的小热休克蛋白（sHSPs）。 | Flynn, C. | N/A | Small heat shock proteins (sHSPs) identified in nodules of tropical woody legumes. | |
| 小细胞肺癌的转移器官倾向性 | Krishnamurthy, M. | N/A | Metastatic organotropism in small cell lung cancer | |
| 一种自主微生物传感器能够长期检测自然土壤中的TNT炸药 | Essington, E. A. | N/A | An Autonomous Microbial Sensor Enables Long-term Detection of TNT Explosive in Natural Soil | |
| 一个强大的合成生物学工具包，用于推进羧酶体研究和设计 | Trettel, D. | N/A | A robust synthetic biology toolkit to advance carboxysome study and design | |
| 两种温度响应RNA协同作用：小RNA CyaR和mRNA ompX | Guanzon, D. A. | N/A | Two temperature-responsive RNAs act in concert: The small RNA CyaR and the mRNA ompX | |
| DNA/多核糖体相分离与细胞宽度限制共同作用，将核区分离与大肠杆菌细胞生长耦合 | Papagiannakis, A. | N/A | DNA/polysome phase separation and cell width confinement couple nucleoid segregation to cell growth in Escherichia coli | |
| MreC-MreD结构揭示了一个多方面的界面，该界面控制着MreC的构象。 | Gilman, M. S. A. | N/A | MreC-MreD structure reveals a multifaceted interface that controls MreC conformation | |
| 异养硝化作用关键酶——丙酮酸肟双加氧酶的结构表征 | Tsujino, S. | N/A | Structural characterization of pyruvic oxime dioxygenase, a key enzyme of heterotrophic nitrification | |
| 解读未被开发的古菌域中RiPPs的化学景观及其潜在生态功能 | Zhiman, S. | N/A | Deciphering the chemical landscape and potential ecological function of RiPPs from the untapped Archaea domain | |
| 环境和饮食塑造了特定地理区域的果蝇黑腹菌群组成。 | Gale, J. T. | N/A | Environment and diet shape the geography-specific Drosophila melanogaster microbiota composition | |
| 通过一种超快速生物过程减轻一氧化二氮排放，实现高浓度N2O的去除 | Maeda, R. | N/A | Mitigating nitrous oxide emission by an ultra-fast bioprocess enabling the removal of high concentration N2O | |
| 硫醇应激促进吡嗪酰胺对抗结核分枝杆菌的作用 | Ostrer, L. | N/A | Thiol Stress Fuels Pyrazinamide Action Against Mycobacterium tuberculosis | |
| MMV大流行响应盒的功能表型分析鉴定出针对疟原虫血液期的阶段特异性抑制剂 | Chandramohanadas, R. | N/A | Functional Phenotyping of MMV Pandemic Response Box Identifies Stage-specific inhibitors Against Blood stage Plasmodium | |
| 大肠杆菌的复制起始蛋白DnaA在染色体上被滴定。 | Olivi, L. | N/A | The Escherichia coli replication initiator DnaA is titrated on the chromosome | |
| AAV Rep中同义突变的增强基因组包装在文库筛选中的作用 | Azim, T. | N/A | Synonymous mutations in AAV Rep enhance genome packaging in a library selection | |
| 使用商业血浆富集策略增强的人脑脊液蛋白质组分析 | Borras, E. | N/A | Enhanced proteome profiling of human cerebrospinal fluid using a commercial plasma enrichment strategy | |
| Vault RNAs通过促进hnRNP C和ELAVL1的核外排，助力病毒感染。 | Stok, J. E. | N/A | Vault RNAs aid viral infection by facilitating nuclear export of hnRNP C and ELAVL1 | |
| 对暴露于农药的克氏原螯虾（Procambarus clarkii）进行转录组和生化分析：种群特异性反应作为污染物抗性的标志？ | Martinez-Alarcon, D. | N/A | Transcriptomic and Biochemical analysis of Procambarus clarkii upon exposure to Pesticides: Population-Specific responses as a sign of pollutant resistance? | |
| 整合近端泛素组学分析用于去泛素酶和E3连接酶底物发现：以USP30为例 | Damianou, A. | N/A | Integrative Proximal-Ubiquitomics Profiling for Deubiquitinase and E3 Ligase Substrate Discovery Applied to USP30 | |
| 重新审视雄蚊的非吸血模式 | Bozic, J. | N/A | Revisiting the paradigm of anhematophagy in male mosquitoes | |
| 可扩展的从猪气管中提取气道粘蛋白的方法 | Yang, S. | N/A | Scalable Extraction of Airway Mucins from Porcine Trachea | |
| 一种用于基因调控的丝状支架 | Rasmussen, T. | N/A | A filamentous scaffold for gene regulation | |
| 钙调蛋白对CHK2激酶的非常规结合抑制了其催化活性 | Horne, C. R. | N/A | Unconventional binding of Calmodulin to CHK2 kinase inhibits catalytic activity | |
| 通过核心变构结构网络调节IL-2免疫信号功能 | Woodward, C. H. | N/A | Regulating IL-2 immune signaling function via a core allosteric structural network | |
| 使用SIREn对冷冻电镜体积集合进行自动化无模型分析 | Kinman, L. F. | N/A | Automated model-free analysis of cryo-EM volume ensembles with SIREn | |
| 乳酸的直接线粒体导入支持了碳水化合物的弹性氧化 | Cluntun, A. A. | N/A | Direct mitochondrial import of lactate supports resilient carbohydrate oxidation | |
| 整合N-糖基化和CODEX成像揭示健康人肺细胞特异性蛋白质糖基化 | Velickovic, D. | N/A | Integrating N-glycan and CODEX imaging reveal cell-specific protein glycosylation in healthy human lung | |
| 利用HILIC/ERLIC分离技术进行RNA聚合酶II C端结构域磷酸肽异构体的在线纳米级LC-MS/MS分析 | Ficarro, S. A. | N/A | Leveraging HILIC/ERLIC Separations for Online Nanoscale LC- MS/MS Analysis of Phosphopeptide Isoforms from RNA Polymerase II C-terminal Domain | |
| 对Pseudomonas putida KT2440 Omega转氨酶结构洞察与合理设计以增强(R)-苯乙酰甲醇至(1R, 2S)-去甲麻黄碱的生物转化 | Das, P. | N/A | Structural insights and rational design of Pseudomonas putida KT2440 Omega transaminases for enhanced biotransformation of (R)-Phenylacetylcarbinol to (1R, 2S)-Norephedrine | |
| 在310K下，对微摩尔浓度的α-突触核蛋白和tau蛋白进行细胞内残基分辨的核磁共振分析 | Cherot, H. | N/A | In-cell residue-resolved NMR of micromolar α-synuclein and tau at 310K | |
| 通过pH缓冲增强酶活性：生物分子凝聚体的贡献 | Stoffel, F. | N/A | Enhancement of Enzymatic Activity by Biomolecular Condensates through pH Buffering | |
| DoriVac（DNA折纸疫苗）在转移性黑色素瘤模型中的疗效验证 | Rajwar, A. | N/A | Validation of DoriVac (DNA origami vaccine) efficacy in a metastatic melanoma model | |
| 伪缺氧稳定化的HIF2α转录抑制MNRR1，MNRR1是MELAS中一个可药物化的靶点 | Purandare, N. | N/A | Pseudohypoxia-stabilized HIF2α transcriptionally inhibits MNRR1, a druggable target in MELAS | |
| # BioRxiv 2024-10-07 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 关于已知最早生命形式的本质 | Kanaparthi, D. | N/A | On the nature of the earliest known life forms | |
| 肠道细菌衍生的鞘脂类物质改变了对口服霍乱疫苗抗原的先天免疫反应 | Chac, D. | N/A | Gut bacteria-derived sphingolipids alter innate immune responses to oral cholera vaccine antigens | |
| 可扩展的基于图像的空间转录组数据集可视化与对齐 | Preibisch, S. | N/A | Scalable image-based visualization and alignment of spatial transcriptomics datasets | |
| PERK激酶活性受铜结合调控——调节内质网应激耐受的新型调控范式 | Newton, S. E. B. | N/A | PERK Kinase Activity is Regulated by Copper Binding-A New Regulatory Paradigm for Modulation of ER Stress Tolerance | |
| 核苷酸变压器：构建和评估人类基因组学的稳健基础模型 | Dalla-Torre, H. | N/A | The Nucleotide Transformer: Building and Evaluating Robust Foundation Models for Human Genomics | |
| 单荧光团成像揭示了生物分子凝聚体的不同环境和结构特征 | Wu, T. | N/A | Single fluorogen imaging reveals distinct environmental and structural features of biomolecular condensates | |
| 双重MAPK抑制触发促炎信号并增强BRAF V600E胶质瘤对T细胞介导的检查点疗法的敏感性 | Xing, Y. L. | N/A | Dual MAPK Inhibition Triggers Pro-inflammatory Signals and Sensitizes BRAF V600E Glioma to T Cell-Mediated Checkpoint Therapy | |
| 稳态突触缩放与稳态结构可塑性之间的相互作用维持了神经网络的稳健放电率。 | Lu, H. | N/A | The interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks | |
| 通过从整体到单细胞的解卷积方法，描绘白血病干细胞的药物敏感性 | Alexandre, C. | N/A | Profiling drug sensitivity of leukemic stem cells via bulk-to-single-cell deconvolution | |
| 在工作记忆中，视觉层次结构逐渐向类别表征过渡，但在感知过程中并非如此。 | Chunharas, C. | N/A | A gradual transition toward categorical representations along the visual hierarchy during working memory, but not perception. | |
| 一种新型泛RAS抑制剂，其独特的作用机制可阻断小鼠模型中胃肠癌的生长 | Foote, J. | N/A | A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer | |
| 使用传递熵测量评估RAS-MAPK系统中的信息流 | Umeki, N. | N/A | Evaluation of information flows in the RAS-MAPK system using transfer entropy measurements | |
| 稳定性指标在不同数据质量下表现稳健，但对社区规模较为敏感。 | O'Brien, D. A. | N/A | Stability metrics are robust across data qualities but sensitive to community size. | |
| RpoS激活了沙门氏菌Typhi生物膜的形成，并驱动其在胆囊中的持久性。 | Desai, S. | N/A | RpoS activates formation of Salmonella Typhi biofilms and drives persistence in the gall bladder | |
| 进化相关性对物种多样化和树形的影响 | Qin, T. | N/A | Impact of Evolutionary Relatedness on Species Diversification and Tree Shape | |
| 古多肽中的电子自旋极化与电荷动力学：它们在蛋白质功能中的作用 | Vyas, P. | N/A | Electron Spin-Polarizability and Charge Dynamics in Ancient Polypeptides : Their Role in Protein Function | |
| 皮质连接组的高阶结构中的特定抑制和去抑制 | Reimann, M. W. | N/A | Specific inhibition and disinhibition in the higher-order structure of a cortical connectome | |
| 使用因果启发的神经网络进行治疗扰动的组合预测 | Gonzalez, G. | N/A | Combinatorial prediction of therapeutic perturbations using causally-inspired neural networks | |
| 通过从相同原始读取数据中提取的保守核基因序列和整个叶绿体基因组，对亚科进化进行了综合研究。 | Witharana, E. P. | N/A | Comprehensive study of subfamily evolution through sequences of conserved nuclear genes and whole chloroplast genomes extracted from the same raw read data | |
| 过量磷酸盐对沿海浮游生物群落的影响：波罗的海中尺度实验 | Spilling, K. | N/A | Effects of excess phosphate on a coastal plankton community: a mesocosm experiment in the Baltic Sea | |
| 一种结核分枝杆菌分泌的毒力因子破坏宿主snRNP生物发生 | Chauhan, K. | N/A | A Mycobacterium tuberculosis secreted virulence factor disrupts host snRNP biogenesis | |
| 探索在不同热带森林、树木组织和发育阶段中的茜草科真菌内生菌 | Castillo-Gonzalez, H. | N/A | Exploring Rubiaceae fungal endophytes across contrasting tropical forests, tree tissues, and developmental stages | |
| 在寄生蜂Lysiphlebus fabarum中，兼性性别是否是两全其美的选择？ | Boulton, R. A. | N/A | Is facultative sex is the best of both worlds in the parasitoid wasp Lysiphlebus fabarum? | |
| 动态强化学习揭示了奖励学习过程中策略随时间变化的转变。 | Venditto, S. J. C. | N/A | Dynamic reinforcement learning reveals time-dependent shifts in strategy during reward learning. | |
| 范德华力、静电作用和氢键在纤维素Iβ和II晶体相对稳定性中的作用 | Kullmann, R. | N/A | Role of van der Waals, electrostatic, and hydrogen-bond interactions for the relative stability of cellulose Iβ and II crystals | |
| 人CTF18夹钳加载器与PCNA结合的结构 | Briola, G. | N/A | Structure of the human CTF18 clamp loader bound to PCNA | |
| 使用Sentence-BERT从预测数据库中提炼疾病中的蛋白质水平微RNA靶标相互作用 | Chen, B. | N/A | Refining Protein-Level MicroRNA Target Interactions in Disease from Prediction Databases Using Sentence-BERT | |
| GTP环水解酶II（gch2）与球蟒中的色觉缺失：基于蝶呤色素沉着的新脊椎动物模型 | Garcia-Elfring, A. | N/A | GTP cyclohydrolase II (gch2) and axanthism in ball pythons: a new vertebrate model for pterin-based pigmentation | |
| 激活血红素代谢促进关节内损伤或手术暴露后的组织健康 | Liman, S. | N/A | Activation of Heme Metabolism Promotes Tissue Health after Intraarticular Injury or Surgical Exposure | |
| NMDARs和协同激动剂的位置控制着黑质多巴胺神经元中爆发的产生 | Ringlet, S. | N/A | Location of NMDARs and co-agonist controls the generation of bursts in nigral dopamine neurons | |
| II型糖尿病中骨骼肌肌球蛋白超松弛与能量代谢失调 | Lewis, C. T. | N/A | Dysregulated Skeletal Muscle Myosin Super-relaxation and Energetics in Type II Diabetes | |
| HIV共受体相关基因（CCR5和CXCR4）启动子甲基化：原创研究 | Esman, A. | N/A | HIV Coreceptors Related Genes (CCR5 and CXCR4) Promoter Methylation: Original Research | |
| MatP在细菌细胞分裂周期时空调控中的生物分子凝聚体的证据 | Barros-Medina, I. | N/A | Evidence for biomolecular condensates of MatP in spatiotemporal regulation of the bacterial cell division cycle | |
| MLCK/MLCP通过重新分布生长锥的F-肌动蛋白来调节哺乳动物轴突的再生 | Saijilafu, | N/A | MLCK/MLCP regulates mammalian axon regeneration via the redistribution of the growth cone F-actin | |
| 大肠杆菌细胞中DnaA和DNA的相对分布作为其表型变异的因素 | Namboodiri, S. K. | N/A | Relative Distribution of DnaA and DNA in Escherichia coli Cells as a Factor of Their Phenotypic Variability | |
| 克服冷冻电镜图各向异性揭示了具有不同化学计量比的ALK-细胞因子复合物 | Felix, J. | N/A | Overcoming cryo-EM map anisotropy reveals ALK-cytokine assemblies with distinct stoichiometries | |
| 外毛细胞搅动耳蜗内的液体 | Lee, C. | N/A | Outer hair cells stir cochlear fluids | |
| 多巴胺与时间折扣：重新审视药理学与个体差异 | Smith, E. | N/A | Dopamine and temporal discounting: revisiting pharmacology and individual differences | |
| IL-6和IL-27负向调控与淋巴驱动性滑膜炎相关的CRTAM表达CD4+ T细胞。 | Derrac Soria, A. | N/A | IL-6 and IL-27 negatively regulate CRTAM-expressing CD4+ T-cells associated with lymphoid-driven synovitis. | |
| 分布式学习推动了统计抑制和聋化 | Luthra, S. | N/A | Distributional learning drives statistical suppression and deafening | |
| 一种受生理启发的混合CPG/反射控制器，用于自行车模拟，并可推广到步行 | Severini, G. | N/A | A physiologically inspired hybrid CPG/Reflex controller for cycling simulations that generalizes to walking | |
| 一个小的信号域控制着磷酸肌醇磷酸酶5激酶（PPIP5K）在磷酸盐稳态中的磷酸酶活性。 | Raia, P. | N/A | A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis. | |
| 一种基于纳米抗体的方法，用于在活细胞中捕获和可视化二元蛋白质复合物的特定相互作用 | Sleiman, N. H. | N/A | A nanobody-based approach to capture and visualize specific interactions of binary protein complexes in living cells | |
| 利用MELISSA模型对整合位点数据进行安全评估 | Lin, T.-Y. | N/A | Modeling integration site data for safety assessment with MELISSA | |
| 全球土壤传播蠕虫的多样性揭示了影响诊断目标的群体偏向性遗传变异 | Papaiakovou, M. | N/A | Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets | |
| 一个支持法国淡水环境中水生大型无脊椎动物DNA条形码分析的注释参考库 | Gauvin, P. | N/A | An annotated reference library for supporting DNA metabarcoding analysis of aquatic macroinvertebrates in French freshwater environments | |
| 斑马鱼Pol-Theta与人Pol-Theta，具有同源功能的直系同源物 | Thomas, C. | N/A | Zebrafish Pol-Theta and Human Pol-Theta, Orthologues with Homologous Function | |
| 微流控技术调控显微切割肿瘤中的微血管 | Nguyen, T. N. H. | N/A | Microfluidic Modulation of Microvasculature in Microdissected Tumors | |
| H3K9甲基化非依赖性活性在异染色质焦点、基因抑制和器官发生中的HPL-2/HP1作用 | Delaney, C. E. | N/A | H3K9 methylation-independent activity for HPL-2/HP1 in heterochromatin foci, gene repression, and organogenesis | |
| IgBlend：在抗体语言模型中统一三维结构和序列 | Malherbe, C. | N/A | IgBlend: Unifying 3D Structures and Sequences in Antibody Language Models | |
| 茄科生物合成基因簇的亚功能化与表观遗传调控 | Priego-Cubero, S. | N/A | Sub-functionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae | |
| 具有改变的RNA结合和降解活性的病理性PNPase变体影响细菌和人类细胞模型的表型 | Pizzoccheri, R. | N/A | Pathological PNPase variants with altered RNA binding and degradation activity affect the phenotype of bacterial and human cell models | |
| 普遍规则支配着质粒拷贝数 | Ramiro-Martinez, P. | N/A | Universal rules govern plasmid copy number | |
| 一种以基因型为先导的方法在狗中识别出与口腔面部裂和其他表型相关的变异 | Buckley, R. M. | N/A | A genotype-first approach identifies variants for orofacial clefts and other phenotypes in dogs | |
| 利用多组儿科临床睡眠数据洞察神经发育：儿科睡眠回顾性分析（RASP）队列研究 | Gong, N. N. | N/A | Leveraging clinical sleep data across multiple pediatric cohorts for insights into neurodevelopment: the Retrospective Analysis of Sleep in Pediatric (RASP) cohorts study | |
| 早期听觉和成年求偶经历与歌者身份相互作用，塑造雌性斑胸草雀对歌声的神经反应 | Catalano, I. | N/A | Early auditory and adult mating experiences interact with singer identity to shape neural responses to song in female zebra finches | |
| 悬浮组织开放式微流控图案化技术（STOMP） | Haack, A. J. | N/A | Suspended Tissue Open Microfluidic Patterning (STOMP) | |
| TSST-1通过激活CD8+T细胞促进金黄色葡萄球菌在阴道内的定植 | Dufresne, K. | N/A | TSST-1 promotes colonization of Staphylococcus aureus within the vaginal tract by activation of CD8+T cells | |
| 青少年在晶体智力和流体智力方面的神经相关性存在差异 | Qiu, B. | N/A | Neural correlates differ between crystallized and fluid intelligence in adolescents | |
| 顶枕叶伽马经颅交流电刺激对视觉空间注意任务中行为表现和神经活动的影响 | Zheng, T. | N/A | After-effects of Parieto-occipital Gamma Transcranial Alternating Current Stimulation on Behavioral Performance and Neural Activity in Visuo-spatial Attention Task | |
| 亨廷顿病小鼠模型中运动学习和皮层纹状体网络活动的早期改变 | Badreddine, N. | N/A | Early alterations of motor learning and corticostriatal network activity in a Huntington's disease mouse model | |
| 阿尔茨海默病相关基因型对老年小鼠慢性诱发性癫痫结果和抗癫痫药物活性的影响存在差异 | Knox, K. | N/A | Alzheimer's disease-associated genotypes differentially influence chronic evoked seizure outcomes and antiseizure medicine activity in aged mice | |
| 驼背时间转录因子决定了果蝇NB5-2谱系中间神经元的分子身份、形态和突触前靶向。 | Pollington, H. Q. | N/A | The Hunchback temporal transcription factor determines interneuron molecular identity, morphology, and presynapse targeting in the Drosophila NB5-2 lineage | |
| 动物声学交流保持着一种普遍的最优节奏 | Piette, T. | N/A | Animal acoustic communication maintains a universal optimum rhythm | |
| 雌性大鼠性行为的时间交配模式 | Oyem, J. C. | N/A | The temporal copulatory patterns of female rat sexual behavior | |
| 钾通道模拟中的电荷缩放：电导、离子占据、电压响应与选择性 | Hui, C. | N/A | Charge Scaling in Potassium Channel Simulations: Conductance, Ion Occupancy, Voltage Response, and Selectivity | |
| 基于化学交换饱和转移的蛋白质次要构象状态精确推断的NMR实验条件自主自适应优化 | Kasai, T. | N/A | Autonomous adaptive optimization of NMR experimental conditions for precise inference of minor conformational states of proteins based on chemical exchange saturation transfer | |
| 组蛋白H3作为核小体核心颗粒中的氧化还原开关：来自分子建模的见解 | Karami, Y. | N/A | Histone H3 as a redox switch in the nucleosome core particle: insights from molecular modeling | |
| 在右美托咪定诱导意识丧失期间大脑连接性和神经血管动力学的变化 | Fotiadis, P. | N/A | Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness | |
| 大脑“暗能量”之谜升级：FDG摄取、递送和磷酸化，及其与静息态脑活动的耦合 | Volpi, T. | N/A | The brain's "dark energy" puzzle upgraded: FDG uptake, delivery and phosphorylation, and their coupling with resting-state brain activity | |
| 复杂的慢波在5-MeO-DMT作用下彻底重塑了人类大脑的动态。 | Blackburne, G. | N/A | Complex slow waves radically reorganise human brain dynamics under 5-MeO-DMT | |
| 与二值化的病灶图像相比，连续的病灶图像能更准确地预测中风后的结果。 | Hope, T. M. H. | N/A | Continuous lesion images drive more accurate predictions of outcomes after stroke than binary lesion images | |
| 大鼠脊髓损伤中基于间充质干细胞衍生的细胞外囊泡疗法的局部细胞因子变化 | Kabdesh, I. | N/A | Local cytokine changes in response to mesenchymal stem cell-derived extracellular vesicles-based therapy in rat spinal cord injury | |
| 调和感觉衰减与增强：自我生成的感觉反馈的时间动态 | Suzuishi, Y. | N/A | Reconcile sensory attenuation and enhancement: The temporal dynamics of self-generated sensory feedback | |
| 神经肽依赖的尖峰时间精确性和昼夜节律输出神经元的可塑性 | Chong, B. | N/A | Neuropeptide-dependent spike time precision and plasticity in circadian output neurons | |
| 在观察动作时，空间信息和解剖结构信息的处理具有不同的时间尺度 | Baptiste, W. M. | N/A | Separate timescales for spatial and anatomical information processing during action observation | |
| 成年大鼠中的多重情境辨别：性别差异及厌恶记忆的时间依赖性泛化动态 | Alves, F. N. L. | N/A | Multiple context discrimination in adult rats: sex variability and dynamics of time-dependent generalization of an aversive memory | |
| 研究非人类灵长类动物三叉神经元机械激活电流 | Lindquist, K. | N/A | Investigating Mechanically Activated Currents from Trigeminal Neurons of Non-Human Primates | |
| 小鼠嗅觉感觉神经元轴突内源性再生的区域性缺陷 | Kunkhyen, T. | N/A | Regional deficits in endogenous regeneration of mouse olfactory sensory neuron axons | |
| 突触前丝状伪足形成动突触，并调节膜力学以促进同步神经传递和癫痫发作。 | Jain, A. | N/A | Presynaptic filopodia form kinapses and modulate membrane mechanics for synchronous neurotransmission and seizure generation. | |
| 视觉皮层中附近刺激之间的抑制性相互作用反映了拥挤现象。 | Soo, L. | N/A | Suppressive interactions between nearby stimuli in visual cortex reflect crowding | |
| 氯胺酮通过小鼠中Ca2+通透性AMPA受体的表达逆转慢性应激引起的行为变化 | Flowers, J. C. | N/A | Ketamine reverses chronic stress-induced behavioral changes via the expression of Ca2+-permeable AMPA receptors in mice | |
| 驱动蛋白自抑制需要肘部磷酸化 | Chen, G. | N/A | Kinesin Autoinhibition Requires Elbow Phosphorylation | |
| 通过机器学习模型进行可扩展且可解释的疾病预测的高维生物标志物识别 | Dai, Y. | N/A | High-dimensional Biomarker Identification for Scalable and Interpretable Disease Prediction via Machine Learning Models | |
| 通过可解释机器学习洞察心力衰竭代谢标志物 | Baron, C. | N/A | Insights into Heart Failure Metabolite Markersthrough Explainable Machine Learning | |
| 斑马鱼模型预测乳腺癌患者化疗反应：迈向个性化医疗的共临床研究 | Mendes, R. V. | N/A | Zebrafish Avatar-test predicts patient's tumor response to chemotherapy in breast cancer: a co-clinical study towards personalized medicine | |
| 绘制乳腺癌在肺和肝转移的生态位 | Sznurkowska, M. K. | N/A | Mapping the niche of breast cancer metastases in lung and liver | |
| 不同综合施肥水平对埃塞俄比亚南部瓦切莫大学大蒜（Allium sativum L.）产量和品质的影响 | Shumbulo, A. | N/A | Garlic (Allium sativum L.) yield and quality as affected by different integrated fertilizer levels at Wachemo university, southern Ethiopia | |
| 树木高度与膨压限制：叶表皮细胞解剖学无证据支持 | Aleman-Sancheschulz, G. | N/A | Turgor limitation of tree height: no evidence from leaf epidermal cell anatomy | |
| 阿片类药物使用者对奖励的前中部扣带回反应迟钝，通过前额叶经颅磁刺激可恢复正常 | Biernacki, K. | N/A | Blunted anterior midcingulate response to reward in opioid users is normalized by prefrontal transcranial magnetic stimulation | |
| 对比功能连接定义了重度抑郁症中神经生理学指导的症状维度 | Zhu, H. | N/A | Contrastive functional connectivity defines neurophysiology-informed symptom dimensions in major depression | |
| 在离线期间的海马体涟漪能够预测人类的运动序列学习 | Chen, P.-C. | N/A | Hippocampal ripples during offline periods predict human motor sequence learning | |
| 探索Instagram在新一代中的教育潜力：一项关于“领养细菌”影响的研究 | Rodrigues Cintra Armellini, B. | N/A | Exploring the Educational Potential of Instagram in the New Generations: A Study on the Impact of "Adopt a Bacterium" | |
| 冰川消退对生态系统发育及碳动态的影响 | Ceresa, E. | N/A | Glacier Retreat Effects On Ecosystem Development And Carbon Dynamics | |
| 揭示“被遗忘的民族”的起源与基因构成：一项关于喀尔巴阡盆地萨尔马提亚时期人口的研究 | Schütz, O. | N/A | Unveiling the Origins and Genetic Makeup of the 'Forgotten People': A Study of the Sarmatian-Period Population in the Carpathian Basin | |
| 近东血统进入意大利中部的时间早于罗马帝国的建立。 | Ravasini, F. | N/A | The arrival of the Near Eastern ancestry in Central Italy predates the onset of the Roman Empire | |
| 利用神经不应期去除电刺激伪影的方法：通过对比阴极和阳极刺激进行验证 | Nakhmani, A. | N/A | A Method for Electrical Stimulus Artifact Removal Exploiting Neural Refractoriness: Validation by Contrasting Cathodic and Anodic Stimulation | |
| Nutri Complex 150+：一种新的面部年轻化有效方法 | Privitera, A. | N/A | Nutri Complex 150+: a new and effective approach to facial rejuvenation | |
| HIV-1出芽需要氧化还原酶MICAL1介导的皮质肌动蛋白解聚 | Serrano, T. | N/A | HIV-1 budding requires cortical actin disassembly by the oxidoreductase MICAL1 | |
| ASCL1介导的染色质结合和基因激活的独特增殖和神经元程序具有细胞周期阶段特异性 | Beckman, W. F. | N/A | Distinct proliferative and neuronal programmes of chromatin binding and gene activation by ASCL1 are cell cycle stage-specific | |
| 由磷脂1,2-二油酰基-sn-甘油-3-磷酸乙醇胺组成的脂质纳米颗粒封装的Spike mRNA疫苗在仓鼠中诱导了强大的B细胞和T细胞反应，这些反应与对COVID-19的保护相关。 | Quadiri, A. | N/A | Spike mRNA Vaccine Encapsulated in a Lipid Nanoparticle Composed of Phospholipid 1,2-Dioleoyl-sn-Glycero-3-Phosphoethanolamine Induced Potent B- and T-cell Responses Associated with Protection against COVID-19 in Hamsters | |
| FungAMR：真菌中抗菌药物耐药性突变的综合概述 | Bedard, C. | N/A | FungAMR: A comprehensive portrait of antimicrobial resistance mutations in fungi | |
| 土壤水分对农业土壤微生物多样性及其酶活性的影响 | Bogati, K. | N/A | Impact of soil moisture on microbial diversity and their enzyme activity on agricultural soil | |
| 建立了一种慢性铜绿假单胞菌小鼠肺部感染模型，模拟了人类囊性纤维化的病理生理学和炎症反应。 | Vaillancourt, M. | N/A | A chronic Pseudomonas aeruginosa mouse lung infection modeling the pathophysiology and inflammation of human cystic fibrosis | |
| 基因组间隔识别码（GenomicGapID）：利用保守基因组位点的空间分布进行广谱微生物鉴定 | Asthana, V. | N/A | GenomicGapID: Leveraging Spatial Distribution of Conserved Genomic Sites for Broad-Spectrum Microbial Identification | |
| 慢性感染可能导致类似SARS-CoV-2的病毒进化爆发，而没有上位效应。 | Rodriguez-Horta, E. | N/A | Chronic infections can generate SARS-CoV-2-like bursts of viral evolution without epistasis | |
| FAN1缺陷促进亨廷顿病的结构和分子基础 | Pluciennik, A. | N/A | Structural and molecular basis of FAN1 defects in promoting Huntington's disease | |
| 人类外泌体的结构延伸通过最小界面实现 | Xu, H. D. | N/A | Structural extension of the human exocyst is enabled by a minimal interface | |
| 用于杆状病毒系统和酵母的多基因载体模块化克隆 | Lai, Z. | N/A | Modular cloning of multigene vectors for the baculovirus system and yeast | |
| 基于细胞的高内涵方法用于SARS-CoV-2中和，识别出独特的单克隆抗体和PI3K通路抑制剂。 | Cabel, C. R. | N/A | Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors. | |
| 基于机器学习的3' UTR设计以提高mRNA稳定性 | Morrow, A. K. | N/A | ML-driven design of 3' UTRs for mRNA stability | |
| 分子状态在胡须皮质神经元细胞类型发育和可塑性中的基础 | Butrus, S. | N/A | Molecular states underlying neuronal cell type development and plasticity in the whisker cortex | |
| 恶性疟原虫Vps16同源物的特征，Vps-2 C连接复合体成员之一。 | Galaup, T. | N/A | Characterization of the Plasmodium falciparum homologue of Vps16, a member of the Vps-2 C tethering complex. | |
| 细菌鞭毛马达速度对质子动力势的非线性依赖性及其对游泳的影响 | Krasnopeeva, E. | N/A | Nonlinear dependency of the bacterial flagellar motor speed on proton motive force and its consequences for swimming | |
| 解码HIV诱导的CPSF6点状结构及其与核斑点的融合过程 | Tomasini, C. D. | N/A | Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle | |
| TGF-beta介导的JunB-HBZ核转位是HTLV-1诱导白血病的关键驱动因素 | Yasunaga, J. | N/A | JunB-HBZ nuclear translocation by TGF-beta is a key driver in HTLV-1-mediated leukemogenesis | |
| 人类尿液中尿路致病细菌的代谢组学调查 | Chan, C. C. | N/A | Metabolomics survey of uropathogenic bacteria in human urine | |
| 扩展中的松露环境：对旧和新块菌属大块菌栖息地中微生物动态的研究 | Rondolini, M. | N/A | The expanding truffle environment: a study of the microbial dynamics in old and new Tuber magnatum Picco habitat | |
| 洋葱叶和鳞茎组织中伯克霍尔德菌（Burkholderia gladioli）的独特致病机制 | Paudel, S. | N/A | Distinct Virulence Mechanisms of Burkholderia gladioli in Onion Foliar and Bulb Scale Tissues | |
| 种族和民族对口腔微生物群的多样性和特征的影响 | Wang, Q. | N/A | Diversity and characteristics of the oral microbiome influenced by race and ethnicity | |
| 转基因水稻品系中甲烷排放量的减少与根际微生物氢循环的改变有关 | Shi, L.-D. | N/A | Reduced methane emissions in transgenic rice genotypes are associated with altered rhizosphere microbial hydrogen cycling | |
| DNA修复基因uvrA发生临床突变，使结核分枝杆菌在宿主体内获得生存优势。 | Saba Naz, | N/A | A clinical mutation in uvrA, a DNA repair gene, confers survival advantage to Mycobacterium tuberculosis in the host | |
| Primosomal蛋白PriC通过绕过DnaA-DnaB相互作用步骤，在oriC处加载DnaB解旋酶，从而缓解复制起始压力。 | Yoshida, R. | N/A | Primosomal protein PriC rescues replication initiation stress by bypassing the DnaA-DnaB interaction step for DnaB helicase loading at oriC | |
| 突变剂对硝基呋喃妥因耐药性发展的进化风险分析 | Kettlewell, R. | N/A | Evolutionary risk analysis of mutators for the development of nitrofurantoin resistance | |
| 巨型病毒创造亚细胞环境以克服密码子-tRNA不匹配 | Zhang, R. | N/A | Giant virus creates subcellular environment to overcome codon-tRNA mismatch | |
| 用于量化病毒准种遗传多样性的相似性加权熵 | Wu, J. | N/A | Similarity-weighted entropy for quantifying genetic diversity in viral quasispecies | |
| 患者对达托霉素耐药性的获得导致果蝇的毒力降低 | Lamy, B. | N/A | Acquisition of daptomycin resistance in patients results in decreased virulence in Drosophila | |
| 纤毛虫藻类Heterosigma akashiwo的病毒感染不仅影响了细胞内有机物的组成，还改变了沿海原核生物群落的动态。 | Takebe, H. | N/A | Viral infection to the raphidophycean alga Heterosigma akashiwo affects both intracellular organic matter composition and dynamics of a coastal prokaryotic community | |
| R5噬菌体在高风险铜绿假单胞菌分离株优势中的作用 | Zhang, L. | N/A | Role of R5 Pyocin in the Predominance of High-Risk Pseudomonas aeruginosa Isolates | |
| 沙门氏菌利用宿主和细菌来源的β-丙氨酸在宿主巨噬细胞内进行复制 | Ma, S. | N/A | Salmonella exploits host- and bacterial-derived β-alanine for replication inside host macrophages | |
| DNA拓扑异构酶I在E. coli中作为转录延伸的超螺旋传感器 | Vidmar, V. | N/A | DNA topoisomerase I acts as supercoiling sensor for transcription elongation in E. coli | |
| 线粒体DNA释放与cGAS-STING通路的激活在致死性Stx12敲除小鼠中的作用 | Kang, J.-S. | N/A | Mitochondrial DNA Release and Activation of the cGAS-STING Pathway in Lethal Stx12 Knockout Mice | |
| 影响埃及伊蚊和白纹伊蚊（双翅目：蚊科）的环境和人为因素，重点在于自然感染和传播：对哥伦比亚新兴媒介的启示。 | Mantilla, J. S. | N/A | Environmental and anthropic factors influencing Aedes aegypti and Aedes albopictus (Diptera: Culicidae), with emphasis on natural infection and dissemination: Implications for an emerging vector in Colombia. | |
| 野生、自由生活的家鼠社会群体中的发声交流具有季节性。 | Jourjine, N. | N/A | Vocal communication is seasonal in social groups of wild, free-living house mice | |
| 利用局部超荷电病毒衣壳进行阴离子环二核苷酸STING激动剂的细胞质递送 | Huang, P. | N/A | Cytosolic delivery of anionic cyclic dinucleotide STING agonists with locally supercharged viral capsids | |
| 计算设计一种用于全细胞生物转化的热稳定从头生物催化剂 | Elaily, W. | N/A | Computational design of a thermostable de novo biocatalyst for whole cell biotransformations | |
| TAOK2 在16p11.2缺失和重复携带者中驱动相反的纤毛长度缺陷 | Ferreccio, A. | N/A | TAOK2 Drives Opposing Cilia Length Deficits in 16p11.2 Deletion and Duplication Carriers | |
| 局部皮质抑制性子网络的形态受到锥体神经元前体类型的影响。 | Gothard, G. | N/A | Local cortical inhibitory subnetworks are shaped by pyramidal neuron progenitor type | |
| 言语产生中从计划到执行的神经机制 | Duraivel, K. | N/A | Neural mechanisms of the transition from planning to execution in speech production | |
| 多重需求网络中信息编码与交换的时空特性分析 | Karimi-Rouzbahani, H. | N/A | Spatiotemporal characterisation of information coding and exchange in the multiple demand network | |
| 奖励和惩罚的偶然性转变揭示了腹侧被盖区多巴胺神经元和GABA神经元在行为灵活性中的不同作用 | Lefner, M. J. | N/A | Reward and punishment contingency shifting reveals distinct roles for VTA dopamine and GABA neurons in behavioral flexibility | |
| APOE4影响皮层神经发育并改变人脑类器官中的网络形成 | Meyer-Acosta, K. K. | N/A | APOE4 impacts cortical neurodevelopment and alters network formation in human brain organoids | |
| 纹状体细胞类型特异性分子特征揭示了肌张力障碍模型中的治疗靶点 | Roman, K. M. | N/A | Striatal cell-type-specific molecular signatures reveal therapeutic targets in a model of dystonia | |
| 感觉皮层中神经元的电学多样性 | Calcini, N. | N/A | Electrical diversity of neurons in sensory cortices | |
| 开发具有广泛治疗潜力的临床可行非肌肉肌球蛋白II小分子抑制剂 | Radnai, L. | N/A | Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential | |
| 香烟烟雾会损害酿酒酵母的胞吞过程。 | shukla, A. | N/A | Cigarette smoke impairs the endocytotic process in Saccharomyces cerevisiae | |
| 时空控制多层同轴流在带有级联喷嘴的3D打印微通道中 | Werner, H. | N/A | Spatiotemporal control of a multilayered co-axial flow in a 3D printed microchannel with cascaded nozzles | |
| TPLATE复合体的结构支架在植物胞吞过程中使膜发生变形。 | Kraus, J. M. | N/A | The structural scaffold of the TPLATE complex deforms the membrane during plant endocytosis | |
| 催产素Gαi信号诱导的杏仁核星形胶质细胞过程回缩塑造行为应激反应 | Baudon, A. | N/A | Oxytocin Gαi signaling-induced amygdala astrocytes processes retraction shapes behavioral stress response | |
| 揭示人结肠上皮类器官中细胞分裂与细胞外基质之间的机械相互作用：基于数字体积相关技术的四维研究 | Magne, L. | N/A | Unveiling mechanical interactions between cell division and extracellular matrix in human colonic epithelium organoids: A 4D study using DVC | |
| 有丝分裂后依赖PP2A-Ankle2的核重组机制 | Li, J. | N/A | Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis | |
| LRRK2突变的微胶质细胞在受到神经黑色素激活时会触发多巴胺能神经退行性变。 | Blasco-Agell, L. | N/A | LRRK2-mutant microglia trigger dopaminergic neurodegeneration when activated by neuromelanin | |
| 急性GARP耗竭会破坏囊泡运输，导致分拣、分泌和O-糖基化出现严重缺陷。 | Khakurel, A. | N/A | Acute GARP depletion disrupts vesicle transport leading to severe defects in sorting, secretion, and O-glycosylation | |
| # BioRxiv 2024-10-06 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 乳腺癌中的DNA甲基化特征：系统综述与Meta分析 | Trasierras-Fresco, A. M. | N/A | DNA Methylation Signatures in Breast Cancer: A Systematic Review and Meta-Analysis | |
| 启动听觉并行处理通路的细胞特化分子逻辑 | Jing, J. | N/A | Molecular logic for cellular specializations that initiate the auditory parallel processing pathways | |
| 机械力在出生后小鼠肌腱发育中作为生物学线索的作用 | Usami, Y. | N/A | Mechanical Force Works as a Biological Cue in Postnatal Murine Tendon Development | |
| 具有生物合成基因突变的肺炎链球菌可减弱疾病症状，但仍保留其对上皮细胞微侵袭和激活上皮细胞先天免疫的潜力。 | Weight, C. M. | N/A | Streptococcus pneumoniae with biosynthesis gene mutations attenuate disease but retain their potential for epithelial microinvasion and epithelial innate immune activation | |
| 黑色素瘤中新诊断和进展相关的微RNA特征 | Gomez-Martinez, H. | N/A | Novel diagnosis- and progression-related microRNA signatures in melanoma | |
| 通用细胞嵌入：细胞生物学的基础模型 | Rosen, Y. | N/A | Universal Cell Embeddings: A Foundation Model for Cell Biology | |
| 通过对从相同原始读取数据中提取的保守核基因序列和整个叶绿体基因组的综合研究，探讨亚家族的进化历程。 | Witharana, E. P. | N/A | Comprehensive study of subfamily evolution through sequences of conserved nuclear genes and whole chloroplast genomes extracted from the same raw read data | |
| 过氧化物酶体增殖物激活受体γ介导的脂质生物合成增强促进了耐药肝细胞环境中结核分枝杆菌的生长。 | Sarkar, B. | N/A | PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in a drug-tolerant hepatocyte environment. | |
| α-突触核蛋白与NOD2相互作用及RIPK2激活在帕金森病中驱动小胶质细胞诱导的神经炎症 | Seo, B. A. | N/A | Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson's Disease | |
| 二元性状模型揭示了HIV-1逃逸T细胞反应的适应性影响 | Gao, Y. | N/A | A binary trait model reveals the fitness effects of HIV-1 escape from T cell responses | |
| gRNAde：用于3D RNA逆向设计的几何深度学习 | Joshi, C. K. | N/A | gRNAde: Geometric Deep Learning for 3D RNA inverse design | |
| 膜定位序列基序对于大肠杆菌RNase E表现出隐性复活是必需的。 | Basak, P. | N/A | The membrane-targeting-sequence motif is required for exhibition of recessive resurrection in Escherichia coli RNase E | |
| 静息状态下不规则的瞳孔波动可预测视觉注意的定向 | Wang, R. | N/A | Aperiodic pupil fluctuations at rest predict orienting of visual attention | |
| 分支增强了嗅觉外周的时间信息编码 | Choi, K. | N/A | Bifurcation enhances temporal information encoding in the olfactory periphery | |
| GPCR的选择性激活：分子动力学显示西波莫德结合但未能激活S1PR2，与S1PR1不同 | Soniya, K. | N/A | Selective Activation of GPCRs: Molecular Dynamics Shows Siponimod Binds but Fails to Activate S1PR2 Unlike S1PR1 | |
| 基因组变异的加性和部分显性效应有助于水稻杂种优势的形成 | Dan, Z. | N/A | Additive and partially dominant effects from genomic variation contribute to rice heterosis | |
| 绿色植物的染色体数目与生殖生命周期：基于系统发生转录组学的视角 | Dhakal, R. | N/A | Chromosome Numbers and Reproductive Life Cycles in Green Plants: A phylo-transcriptomic perspective | |
| 高效整合空间组学数据，实现联合域检测、匹配与对齐的stMSA方法 | Shu, H. | N/A | Efficient integration of spatial omics data for joint domain detection, matching, and alignment with stMSA | |
| 丙酮酸激酶的变构效应通过诱导三羧酸循环涡流和葡萄糖U型转弯，抵抗高血糖、肥胖和炎症。 | Zhang, X. | N/A | Pyruvate kinase allostery resist hyperglycemia, obesity and inflammation by inducing TCA vortex and glucose U turn | |
| 小脑如何自动化和协调无意识的运动序列？ | Gilbert, M. | N/A | How does the cerebellum automate and coordinate unconscious motor sequences? | |
| III型干扰素通过触发细胞死亡独立于STAT激活来抑制甲型流感病毒感染 | Prus, W. | N/A | Type III interferons suppress influenza A virus infection independently of STAT activation by triggering cell death | |
| scChat：基于大型语言模型的单细胞RNA测序分析上下文助手 | Lu, Y.-C. | N/A | scChat: A Large Language Model-Powered Co-Pilot for Contextualized Single-Cell RNA Sequencing Analysis | |
| BioLLMNet：利用专用跨LLM转换网络增强RNA相互作用预测 | Tahmid, M. T. | N/A | BioLLMNet: Enhancing RNA-Interaction Prediction with a Specialized Cross-LLM Transformation Network | |
| 行为控制的类脑神经动力学通过强化学习得以发展 | Codol, O. | N/A | Brain-like neural dynamics for behavioral control develop through reinforcement learning | |
| 第六层皮层丘脑神经元通过皮层间和皮层丘脑皮层通路诱发高伽马振荡 | Russo, S. | N/A | Layer 6 corticothalamic neurons induce high gamma oscillations through cortico-cortical and cortico-thalamo-cortical pathways | |
| 人类腹侧颞叶皮层中感知和想象物体共享的代码 | Wadia, V. S. | N/A | A shared code for perceiving and imagining objects in human ventral temporal cortex | |
| 人类腹侧颞叶皮层中感知和想象物体共享的代码 | Wadia, V. S. | N/A | A shared code for perceiving and imagining objects in human ventral temporal cortex | |
| 更年期下丘脑衰老的转录组学洞察：人类和小鼠模型的比较分析 | Bloom, J. C. B. | N/A | Transcriptomic Insights into Hypothalamic Aging During Menopause: A Comparative Analysis of Human and Mouse Models | |
| 家猫（Felis catus）对物体恒常性的认知：通过主人和陌生人的预期违背实验 | Forman, J. | N/A | Object permanence in domestic cats (Felis catus) using violation-of-expectancy by owner and stranger | |
| 神经调节对沿单峰-跨峰梯度传播脑波的影响 | Maki-Marttunen, V. | N/A | Neuromodulatory influences on propagation of brain waves along the unimodal-transmodal gradient | |
| 非人灵长类动物初级运动皮层中熟练连续运动的逐步巩固 | Ohbayashi, M. | N/A | Gradual consolidation of skilled sequential movements in primary motor cortex of non-human primates | |
| 亲子脑相似性：性别组合中的特异性与共性——传递辐射个性给后代（TRIO）研究 | Matsudaira, I. | N/A | Parent-offspring brain similarity: Specificities and commonalities across gender combinations - the Transmit Radiant Individuality to Offspring (TRIO) study | |
| 对行为库的完整描述揭示了斑马鱼幼鱼捕食行为的原则。 | Rubinstein, Y. | N/A | A complete account of the behavioral repertoire uncovers principles of larval zebrafish hunting behavior | |
| 用于完整大脑中PTEN动态荧光寿命成像的基因编码生物传感器 | Kagan, T. | N/A | Genetically encoded biosensor for fluorescence lifetime imaging of PTEN dynamics in the intact brain | |
| 果蝇在嗅觉导航过程中工作记忆与证据整合的神经动力学 | Kathman, N. D. | N/A | Neural dynamics for working memory and evidence integration during olfactory navigation in Drosophila | |
| 南极磷虾（Euphausia superba）的行为活动由一个昼夜节律钟驱动，这为季节性时间调节提供了一种潜在的机制。 | Hüppe, L. | N/A | A circadian clock drives behavioral activity in Antarctic krill (Euphausia superba) and provides a potential mechanism for seasonal timing | |
| 影响评估与原住民权利：芬兰穆杜斯亚夫里驯鹿放牧合作社林业对冬季牧场的累积影响评估 | Saijets, J. | N/A | Impact assessment and indigenous rights: Cumulative impact assessment of forestry on winter pastures in Mudusjävri reindeer herding co-operative in Finland | |
| 视觉引导接近行为中的性二态性在青春期独特地出现 | Gonzalez-Olvera, R. | N/A | SEXUAL-DIMORPHISM IN VISUALLY GUIDED APPROACH BEHAVIOR EMERGES UNIQUELY DURING ADOLESCENCE | |
| 与Vertec相比，Jumpster基于加速度计的应用程序在完成反向运动跳跃时的可靠性和有效性 | Holman, M. E. | N/A | Reliability and Validity of the Jumpster accelerometer-based app compared to the Vertec when completing a countermovement jump | |
| p53异构体具有高聚集倾向，能与伴侣蛋白相互作用，但缺乏与p53相互作用伙伴的结合能力。 | Brdar, A. | N/A | p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners | |
| 年龄诱导的BMP信号通过抑制ICAT介导的Wnt通路来促进骨关节炎。 | Kumar, B. | N/A | Age-induced BMP signaling inhibits the ICAT-mediated Wnt pathway to promote osteoarthritis. | |
| Lgi3-4对IKur调控的新见解：对心房颤动的启示 | Socuellamos, P. G. | N/A | Novel insights into IKur modulation by Lgi3-4: Implications in atrial fibrillation | |
| PII1/MRC与拟南芥中的淀粉合成酶4（SS4）的相互作用抑制了SS4的酶活性。 | Bossu, M. | N/A | PII1/MRC interaction with Starch Synthase 4 (SS4) from Arabidopsis thaliana inhibits SS4 enzymatic activity | |
| 化学定义的脂质饮食揭示了基因组最小细胞中脂质组重塑的多功能性 | Safronova, N. | N/A | Chemically defined lipid diets reveal the versatility of lipidome remodeling in genomically minimal cells | |
| 油质真菌优化见解——Umbelopsis sp. WA50703的全基因组代谢重构与分析 | Dziurzynski, M. | N/A | Insights into optimization of oleaginous fungi - genome-scale metabolic reconstruction and analysis of Umbelopsis sp. WA50703 | |
| 在神经形态硬件上实现的生物学上逼真的新皮层计算基元提升了视觉变换器的性能 | Iqbal, A. | N/A | Biologically Realistic Computational Primitives of Neocortex Implemented on Neuromorphic Hardware Improve Vision Transformer Performance | |
| 利用单细胞RNA测序生成稳健的微胶质细胞衰老时钟 | Stanley, N. | N/A | Leveraging Single-Cell RNA-Seq to Generate Robust Microglia Aging Clocks | |
| 在小鼠视觉皮层胚胎期和出生后发育过程中持续的细胞类型多样化 | Gao, Y. | N/A | Continuous cell type diversification throughout the embryonic and postnatal mouse visual cortex development | |
| 工作记忆提取中的速度与准确性权衡及老年男女双侧楔前叶的差异 | Esiaka, D. | N/A | Differential Speed and Accuracy Trade-off in Working Memory Retrieval and Bilateral Precuneus between Older Men and Women | |
| 大豆（Glycine max (L.) Merril）种质资源的遗传多样性和群体结构。 | SILUE, T. | N/A | Genetic diversity and population structure of soybean (Glycine max (L.) Merril) germplasm. | |
| 更新后的锥虫核孔及其相关蛋白图谱 | Gabiatti, B. P. | N/A | An updated map of the trypanosome nuclear pore and its associated proteins | |
| 疟原虫HOPS/CORVET复合体对于内吞作用和入侵器官的功能至关重要。 | Mesen-Ramirez, P. | N/A | Malaria parasite HOPS/CORVET complexes are critical for endocytosis and invasion organelles function | |
| MicroBayesAge：一种利用微阵列数据预测表观遗传年龄的最大似然方法 | Nolan, N. | N/A | MicroBayesAge: A Maximum Likelihood Approach to Predict Epigenetic Age Using Microarray Data | |
| pLM-DBPs：利用蛋白质语言模型嵌入增强植物中DNA结合蛋白预测 | Pokharel, S. | N/A | pLM-DBPs: Enhanced DNA-Binding Protein Prediction in Plants Using Embeddings From Protein Language Models | |
| 溶剂动力学与蛋白质动力学的耦合有助于驱动表皮生长因子受体（EGFR/ErbB1/HER1）激酶域中外显子19缺失突变体的功能差异 | Patil, K. | N/A | Coupled Solvent Dynamics and Protein Dynamics Help Drive Functional Differences in Exon-19 Deletion Mutants in the Epidermal Growth Factor Receptor (EGFR/ErbB1/HER1) Kinase Domain | |
| 小麦条锈病抗性基因Yr9源自黑麦，是一个高度保守的NLR簇中的CC-NBS-LRR基因。 | Yu, Y. | N/A | Wheat stripe rust resistance gene Yr9, derived from rye, is a CC-NBS-LRR gene in a highly conserved NLR cluster | |
| 耦合生长的微生物生物合成动物色素黄蝶呤 | Bushin, L. B. | N/A | Growth-coupled microbial biosynthesis of the animal pigment xanthommatin | |
| 单细胞分辨率图谱揭示了先天样淋巴细胞对土拉弗朗西斯菌感染的反应，并揭示了MAIT细胞在预防类土拉菌病中的作用 | JOYCE, S. | N/A | Single-cell resolution map of innate-like lymphocyte response to Francisella tularensis infection reveals MAIT cell role in protection from tularemia-like disease | |
| 二氢乳清酸脱氢酶抑制剂与4'-氟尿苷的广谱抗病毒活性具有协同作用 | Schrell, L. | N/A | Inhibitors of dihydroorotate dehydrogenase synergize with the broad antiviral activity of 4'-fluorouridine | |
| 便携式现场DNA测序技术用于快速检测病原体及抗菌药物耐药性：概念验证研究 | Pillay, S. | N/A | Portable In-Field DNA Sequencing for Rapid Detection of Pathogens and Antimicrobial Resistance: A Proof-of-Concept Study | |
| 宿主遗传及其/或其微生物群对杂交无胸腺裸鼠棒状杆菌相关角化过度严重程度的影响 | Michelson, A. | N/A | The Impact of Host Genetics and/or its Microbiota on the Severity of Corynebacterium-Associated Hyperkeratosis in Outbred Athymic Nude Mice | |
| 基于荧光的CRISPR干扰系统用于分枝杆菌中可控的基因抑制和活体单细胞成像 | Laudouze, J. | N/A | Fluorescence-based CRISPR interference system for controlled genetic repression and live single-cell imaging in mycobacteria | |
| 光激活分子纳米机器在耻垢分枝杆菌中的杀菌机制：病原菌模型研究 | Galbadage, T. | N/A | Microbicidal Mechanisms for Light-Activated Molecular Nanomachines in Mycobacterium smegmatis: A Model for Pathogenic Bacteria | |
| 哺乳细胞中热休克反应调控中mRNA操纵子形成的保守性 | Pataki, E. | N/A | Conservation of mRNA operon formation in the control of the heat shock response in mammalian cells | |
| Fn14信号在成年骨骼肌修复过程中调控卫星细胞的自我更新和扩增 | Tomaz Da Silva, M. | N/A | Fn14 signaling regulates satellite cell self-renewal and expansion during adult skeletal muscle repair | |
| TWEAK/Fn14信号传导促进癌症恶病质期间的骨骼肌消耗。 | Tomaz da Silva, M. | N/A | The TWEAK/Fn14 signaling promotes skeletal muscle wasting during cancer cachexia | |
| 鉴定出一种新的恶性疟原虫E2泛素结合酶 | Smith, C. | N/A | Identification of a new Plasmodium falciparum E2 ubiquitin conjugating enzyme | |
| 单细胞成像揭示了Bck2在酿酒酵母细胞大小适应营养挑战中的关键作用 | Chadha, Y. | N/A | Single-cell imaging reveals a key role of Bck2 in budding yeast cell size adaptation to nutrient challenges | |
| 插入偏倚对piRNA簇中转座元件侵入的影响 | Pritam, S. | N/A | The impact of insertion bias into piRNA clusters on the invasion of transposable elements | |
| 合作塑造了细菌生态位宽度进化和多样化模式 | Hao, C. | N/A | Cooperation shapes bacterial niche breadth evolution and patterns of diversification | |
| 黑麦1RS染色体上编码CC-NBS-LRR蛋白的基因赋予小麦条锈病抗性 | Han, F. | N/A | Gene encoding CC-NBS-LRR protein on rye chromosome 1RS confers wheat stripe rust resistance | |
| 单细胞RNA测序揭示小鼠动脉粥样硬化过程中血管外膜成纤维细胞的改变 | Fries, L. E. | N/A | Single-Cell RNA-Seq Reveals Adventitial Fibroblast Alterations during Mouse Atherosclerosis | |
| 使用Gnodes测量动植物基因组的DNA含量，长话短说。 | Gilbert, D. | N/A | Measuring DNA contents of animal and plant genomes with Gnodes, the long and short of it. | |
| 计算洞察C肽灵活性驱动的迷你胰岛素在受体结合中的变构行为 | AYAN, E. | N/A | Computational Insights into the Allosteric Behavior of Mini-Insulin in Receptor Binding Driven by C-Peptide Mobility | |
| 白茶通过调节大鼠体内的Apelin和胰岛素水平，缓解了与肥胖相关的代谢紊乱。 | SÜMER, A. | N/A | White Tea Mitigates Obesity-Related Metabolic Disorders Through Apelin and Insulin Modulation in Rats | |
| P450酶催化的无前导核糖体肽的联芳基大环化 | Liu, R. | N/A | P450-Catalyzed Biaryl Macrocyclization of Leaderless Ribosomal Peptides | |
| 反应性氮物质（RNS）及其与反应性氧物质（ROS）在pH中性的高强度等离子体活化水中的反应中间体，决定了其对ESKAPE病原体的抗菌活性。 | Mukherjee, D. | N/A | Reactive nitrogen species (RNS) and its reaction intermediates with reactive oxygen species (ROS) in pH-neutral high-strength plasma-activated water determines the antimicrobial activity against ESKAPE Pathogens | |
| 通过共享字典学习进行微生物组数据整合 | Yuan, B. | N/A | Microbiome Data Integration via Shared Dictionary Learning | |
| Inv(16)癌基因CBFB::MYH11的丢失消除了血液和脾脏中的白血病，但未影响骨髓中的白血病。 | Panda, S. | N/A | Loss of the Inv(16) Oncogene CBFB::MYH11 Eliminates Leukemia from the Blood and Spleen, but not the Bone Marrow | |
| 绘制PTEN突变图谱：肺癌的结构和功能驱动因素 | Hossain, M. U. | N/A | Mapping the PTEN Mutation Landscape: Structural and Functional Drivers of Lung Cancer | |
| 从头设计具有设计配比的α-螺旋肽通道 | Niitsu, A. | N/A | De novo design of α-helical peptide channels with designer stoichiometry | |
| 通过整合活细胞和合成细胞实现混合三维培养的自组装 | Piernitzki, N. | N/A | Self-assembly of hybrid 3D cultures by integrating living and synthetic cells | |
| 普拉梭菌（Faecalibacterium prausnitzii）在人类单核细胞中诱导抗炎反应和代谢重编程 | Danne, C. | N/A | Faecalibacterium prausnitzii induces an anti-inflammatory response and a metabolic reprogramming in human monocytes | |
| 膜表达增强病毒衣壳蛋白的折叠、多聚体结构形成及免疫原性 | Cui, J. | N/A | Membrane Expression Enhances Folding, Multimeric Structure Formation, and Immunogenicity of Viral Capsid Proteins | |
| 大肠杆菌对阿莫西林的遗传适应性：dinB和katE的有限作用 | Teichmann, L. H. | N/A | Genetic Adaptation to Amoxicillin in Escherichia coli: The Limited Role of dinB and katE | |
| 埃博拉病毒基质蛋白引发炎症激活的新机制与埃博拉病毒毒力相关 | Yamaoka, S. | N/A | Novel Mechanism of Inflammatory Activation by Ebola Virus Matrix Protein Linked to the Ebolavirus Virulence | |
| 气道上皮连接减弱和中性粒细胞弹性蛋白酶释放增强，共同导致了肺炎球菌性肺炎后年龄依赖性的菌血症风险增加。 | Xu, S. | N/A | Weakened airway epithelial junctions and enhanced neutrophil elastase release contribute to age-dependent bacteremia risk following pneumococcal pneumonia | |
| 土壤微生物群的扰动阻碍了垂穗草（Bouteloua curtipendula）的生长，并增加了土壤微生物病原体的相对丰度。 | Hobbs, A. | N/A | Soil microbiome perturbation impedes growth of Bouteloua curtipendula and increases relative abundance of soil microbial pathogens | |
| 果蝇piRNA通路中蛋白质相互作用的反复创新 | Riedelbauch, S. | N/A | Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway | |
| 胶质母细胞瘤中的拼接失调改变了与细胞迁移相关基因的功能 | Seong, M. | N/A | Splicing dysregulation in glioblastoma alters the function of cell migration-related genes | |
| 土地利用变化影响全球生物多样性热点地区根-真菌网络的连通性 | Carneiro de Melo Moura, C. | N/A | Land-use changes impact root-fungal network connectivity in a global biodiversity hotspot | |
| 值得深入探讨的话题：食果鱼类牙齿压痕的力学原理 | Rosen, J. | N/A | Something to sink your teeth into: the mechanics of tooth indentation in frugivorous fishes | |
| 基因组和进化证据表明草类异源多倍体短柄草（Brachypodium hybridum）具有干旱适应性 | Wang, Y. | N/A | Genomic and evolutionary evidence for drought adaptation of grass allopolyploid Brachypodium hybridum | |
| 一种古老的溶菌酶存在于扁盘动物中 | Berndt, H. | N/A | An ancient lysozyme in placozoans | |
| 快速且经济高效地生产高质量昆虫基因组序列 | Gilligan, J. | N/A | Rapid and cost-effective production of high-quality insect genome sequences | |
| 基于基因共表达和共进化的蛋白质-蛋白质直接相互作用及稳定复合物的预测与发现 | Miglionico, P. | N/A | Prediction and discovery of protein-protein direct interactions and stable complexes based on gene co-expression and co-evolution | |
| 如何为病毒蛋白选择最佳的零样本模型？ | Yu, Y. | N/A | How to select the best zero-shot model for the viral proteins? | |
| ProteinAligner：一种用于蛋白质基础模型的多模态预训练框架 | Zhang, L. | N/A | ProteinAligner: A Multi-modal Pretraining Framework for Protein Foundation Models | |
| E(Q)AGNN-PPIS：用于蛋白质-蛋白质相互作用位点预测的注意力增强等变图神经网络 | Animesh, A. | N/A | E(Q)AGNN-PPIS: Attention Enhanced Equivariant Graph Neural Network for Protein-Protein Interaction Site Prediction | |
| Tau加速微管网格中的微管蛋白交换 | Biswas, S. | N/A | Tau accelerates tubulin exchange in the microtubule lattice | |
| 集体变形虫样动力学驱动耐药性卵巢癌细胞的侵袭 | Goutham, S. | N/A | Collective amoeboid dynamics drives colonization of drug-resistant ovarian cancer cells | |
| 内源性亨廷顿蛋白聚集体是一个巨大的有组织的支架，为突变亨廷顿蛋白损害的高尔基体提供模板。 | Ma, L. | N/A | Endogenous Huntingtin aggregates are a huge organized scaffold and mold for Golgi apparatus impaired by mutant Huntingtin protein | |
| 低R:FR处理下的玉米植株挥发物增加了其邻近植株食草动物诱导的挥发物排放 | Escobar Bravo, R. | N/A | Volatiles from low R:FR-treated maize plants increase the emission of herbivore-induced plant volatiles in their neighbors | |
| 水热预处理使泥炭易于酶解糖化。 | Thomsen, J. | N/A | Hydrothermal pretreatment renders peat susceptible to enzymatic saccharification | |
| 温度对桃蚜（Myzus persicae）生活史特征及其在马铃薯作物中传播马铃薯Y病毒（PVY）效率的影响 | Sokame, B. M. | N/A | Effects of temperature on the life-history traits of Myzus persicae and its efficiency in transmitting potato virus Y (PVY) in potato crops | |
| 预测京都基因与基因组百科全书中定义的所有通路及其相关化合物条目的通路参与情况 | Huckvale, E. D. | N/A | Predicting The Pathway Involvement For All Pathway and Associated Compound Entries Defined in the Kyoto Encyclopedia of Gene and Genomes | |
| 金丝雀交配季节的歌声在有序与无序之间游走 | Levin, S. | N/A | Canary Mating Season Songs Move Between Order and Disorder | |
| 靶向DNA-PK是一种高度保守的痘病毒先天免疫逃避机制 | Oliveira, M. | N/A | Targeting DNA-PK is a highly conserved poxvirus innate immune evasion mechanism | |
| 决策分析显示，基于社区的监测在马达加斯加具有科学和经济价值。 | Soifer, L. | N/A | Decision analysis shows scientific and economic value of community-based monitoring in Madagascar | |
| 雄性果蝇选择体型较大的雌性作为配偶的遗传变异 | Freed, G. S. | N/A | Genetic variation in male mate choice for large females in Drosophila melanogaster | |
| 验证Pocheina属（Acrasidae科，异鞭毛虫纲，挖掘类）导致在Acrasidae科内识别出三个主要谱系。 | Tice, A. K. | N/A | Validating the genus Pocheina (Acrasidae, Heterolobosea, Excavata) leads to the recognition of three major lineages within Acrasidae | |
| 高纵横比氧化石墨烯：一种高效植物种子质粒DNA传递载体 | Jiang, C. | N/A | High aspect ratio graphene oxide: a highly efficient plasmid DNA deliverer for plant seed | |
| 人类疾病中病毒转录调节因子的鉴定与目录 | Citu, C. | N/A | Identification and catalogue of viral transcriptional regulators in human diseases | |
| 小角度散射测量信号的信息论优化 | Rambo, R. P. | N/A | Information Theory Optimization of Signals from Small Angle Scattering Measurements | |
| 青春期雌性小鼠控制生育的下丘脑神经元中的神经可塑性 | Zhang, Y. | N/A | Neuronal plasticity at puberty in hypothalamic neurons controlling fertility in female mice | |
| 肿瘤抑制因子NME1/NM23-H1调节NF-κB RelA的DNA结合 | Shahabi, S. | N/A | Tumor suppressor NME1/NM23-H1 modulates DNA binding of NF-κB RelA | |
| 来自新型脊索瘤细胞系ARF-8的细胞外囊泡在与亲本细胞和人成骨细胞共培养时，促进了肿瘤发生微环境的改变。 | Nguyen, K. N. | N/A | Extracellular vesicles from a novel chordoma cell line, ARF-8, promote tumorigenic microenvironmental changes when incubated with the parental cells and with human osteoblasts. | |
| Rho激酶抑制剂对翼状胬肉细胞纤维化的抑制作用 | Dai, J. | N/A | Inhibition of pterygium cell fibrosis by the Rho kinase inhibitor | |
| 一种基于纤连蛋白（FN）-丝素蛋白的三维细胞培养模型，作为子宫内膜异位症再利用抗纤维化药物候选物的筛选工具 | Teworte, S. | N/A | A Fibronectin (FN)-Silk 3D Cell Culture Model as a Screening Tool for Repurposed Antifibrotic Drug Candidates for Endometriosis | |
| GLP-1类似物，即艾塞那肽-4，通过中枢传递在去卵巢小鼠中改善了骨骼材料特性和强度。 | Mermet, M. | N/A | The GLP-1 analogue, exendin-4, improves bone material properties and strength through a central relay in ovariectomized mice | |
| # BioRxiv 2024-10-05 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 乳腺癌分泌的因子通过抑制Rac1的激活，导致大鼠肌管萎缩并减少基础及胰岛素刺激的葡萄糖摄取。 | Ali, M. S. | N/A | Breast cancer-secreted factors induce atrophy and reduce basal and insulinstimulated glucose uptake by inhibiting Rac1 activation in rat myotubes | |
| 在学习过程中，皮层L5树突中的未签名时间差误差 | Schoenfeld, G. | N/A | Unsigned temporal difference errors in cortical L5 dendrites during learning | |
| 霍乱弧菌中的氨基糖苷耐药性涉及与tRNA修饰相关的翻译重编程，这种修饰涉及queuosine。 | Fruchard, L. | N/A | Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification | |
| Arche：一种用于微生物基因组片段功能高通量注释的高级灵活工具 | Alonso-Reyes, D. G. | N/A | Arche: An Advanced Flexible Tool for High-throuput Annotation of Functions on Microbial Contigs | |
| 发现微型循环神经网络的认知策略 | Ji-An, L. | N/A | Discovering Cognitive Strategies with Tiny Recurrent Neural Networks | |
| 通过多尺度模拟从头预测HIV-1 MPER抗体的特定磷脂复合物及膜结合 | Maillie, C. A. | N/A | Ab initio prediction of specific phospholipid complexes and membrane association of HIV-1 MPER antibodies by multi-scale simulations | |
| 通过冷冻电镜解析人类MutSβ的多种高分辨率状态，揭示了ATP/ADP结合与异源双链DNA识别之间的相互作用 | Lee, J.-H. | N/A | Elucidation of multiple high-resolution states of human MutSβ by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognition | |
| 晚更新世小脑型人属纳莱迪人的意义建构行为：背景与进化意义 | Fuentes, A. | N/A | Meaning-making behavior in a small-brained hominin, Homo naledi, from the late Pleistocene: contexts and evolutionary implications | |
| 上下文相关的多感官整合：机械感觉的鲁棒性能依赖于亮度 | Sharma, V. P. | N/A | Context dependent multisensory integration: Mechanosensation depends on luminance for robust performance | |
| 分子伴侣的局部合成维持了神经元的蛋白质稳态 | Alecki, C. | N/A | Localized synthesis of molecular chaperones sustains neuronal proteostasis | |
| A型主动脉夹层在夹层前、夹层后及修复后的生物力学应力分析 | Sun, C. | N/A | Biomechanical stress analysis of Type-A aortic dissection at pre-dissection, post-dissection, and post-repair states | |
| 基于图像的力学推断通过生物力学仿真实现 | Vanslambrouck, M. | N/A | Image-based force inference by biomechanical simulation | |
| 基于三维催化域拓扑结构的原核DNA甲基转移酶新型分类系统 | Samokhina, M. | N/A | A Novel Classification System for Prokaryotic DNA Methyltransferases Based on 3D Catalytic Domain Topology | |
| 量化非B DNA基序在癌症中作为非B负担标记的普遍性：使用NBBC | Xu, Q. | N/A | Quantifying the Prevalence of Non-B DNA Motifs as a Marker of Non-B Burden in Cancer using NBBC | |
| 植物细胞类型特异性顺式调控元件的演变 | Yan, H. | N/A | Evolution of plant cell-type-specific cis-regulatory elements | |
| β-1,2-葡聚糖酶的广泛分布：发现新的β-1,2-葡聚糖酶糖苷水解酶家族 | Nakajima, M. | N/A | Extensive distribution of β-1,2-glucanases: finding of new glycoside hydrolase families of β-1,2-glucanases | |
| 微管力在LMNA心肌病中驱动核损伤 | Amiad Pavlov, D. | N/A | Microtubule forces drive nuclear damage in LMNA cardiomyopathy | |
| 利用基因表达和机器学习预测与适应性相关的特征 | Henry, G. A. | N/A | Predicting fitness related traits using gene expression and machine learning | |
| 树序列作为群体遗传推断的通用工具 | Whitehouse, L. S. | N/A | Tree sequences as a general-purpose tool for population genetic inference | |
| 利用血清学调查优化人畜共患病原体的监测 | Clancey, E. | N/A | Using serosurveys to optimize surveillance for zoonotic pathogens | |
| 帕金森病中α-突触核蛋白与NOD2相互作用及RIPK2激活驱动小胶质细胞介导的神经炎症 | Seo, B. A. | N/A | Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson's Disease | |
| Ramp协议：利用TeensyStep揭示个体在步行时对听觉节拍的差异 | Zagala, A. | N/A | The Ramp protocol: Uncovering individual differences in walking to an auditory beat using TeensyStep | |
| 基因组简化：突变率和种群大小对基因组大小缩减的影响 | Luiselli, J. | N/A | Genome streamlining: effect of mutation rate and population size on genome size reduction | |
| 果蝇哈姆雷特介导了生殖系统的上皮组织组装 | Wang, H. | N/A | Drosophila Hamlet mediates epithelial tissue assembly of the reproductive system | |
| MRAP2 修饰了黑皮质素-4受体的信号传导和寡聚状态 | Sohail, I. | N/A | MRAP2 modifies signaling and oligomerization state of the melanocortin-4 receptor | |
| 图对比学习作为高级单细胞RNA测序数据分析的多功能基础 | Zhang, Z. | N/A | Graph Contrastive Learning as a Versatile Foundation for Advanced scRNA-seq Data Analysis | |
| EpiCHAOS：一种用于量化单细胞数据中表观基因组异质性的指标 | Kelly, K. | N/A | EpiCHAOS: a metric to quantify epigenomic heterogeneity in single-cell data | |
| 岩藻糖基转移酶2在过敏性气道高反应性和粘液阻塞中的需求 | Hara, N. | N/A | Requirement for Fucosyltransferase 2 in Allergic Airway Hyperreactivity and Mucus Obstruction | |
| 注意错误会自适应地扭曲空间认知 | Brissenden, J. A. | N/A | Errors of attention adaptively warp spatial cognition | |
| 通过随机连接的前馈网络中的树突计算来区分神经集合模式 | Somashekar, B. P. | N/A | Discriminating neural ensemble patterns through dendritic computations in randomly connected feedforward networks | |
| 扩展任务开始时的元控制需求与其后续执行过程中的控制需求在类别上存在显著差异。 | Akgur, B. F. | N/A | Meta-Control Demands at the Beginning of Extended Tasks are Categorically Different from Control Demands During Their Subsequent Execution | |
| 齿状回中功能失调的S1P/S1PR1信号传导导致慢性疼痛相关记忆障碍的易感性 | Cui, M. | N/A | Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment | |
| 一年内皮层厚度、表面积和脑体积的受试者内稳定性 | Wang, M.-Y. | N/A | The within-subject stability of cortical thickness, surface area, and brain volumes across one year | |
| 单核转录组分析揭示了肌纤维XBP1在再生肌生成中的调控回路 | Joshi, A. S. | N/A | Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis | |
| AlphaFold3 晶状体中的非标准蛋白质 - 淀粉样蛋白案例研究 | Wojciechowska, A. W. | N/A | Non-standard proteins in the lenses of AlphaFold3 - case study of amyloids | |
| 单细胞线粒体DNA突变分析中的假象误导了系统发育推断 | Lareau, C. A. | N/A | Artifacts in single-cell mitochondrial DNA mutation analyses misinform phylogenetic inference | |
| 完成对猿类基因组的完整测序 | Yoo, D. | N/A | Complete sequencing of ape genomes | |
| ImPaqT - 一个基于Golden Gate技术的斑马鱼转基因工具包 | Hurst, S. | N/A | ImPaqT - A Golden Gate-based Toolkit for Zebrafish Transgenesis | |
| 发现不确定性：贝叶斯构成性人工神经网络 | Linka, K. | N/A | Discovering uncertainty: Bayesian constitutive artificial neural networks | |
| 交配系统对多个属谱系分化的影响分析 | Xu, K. | N/A | Analysis of the effects of mating systems on lineage diversification across multiple genera | |
| 在蜂鸟蛾中，飞行控制的并行路径整合反映了自然视觉线索的普遍性和相关性。 | Stoeckl, A. | N/A | Integration of parallel pathways for flight control in a hawkmoth reflects prevalence and relevance of natural visual cues | |
| 两百年来环境变化中植物-真菌共生现象的日益普遍 | Fowler, J. C. | N/A | Increasing prevalence of plant-fungal symbiosis across two centuries of environmental change | |
| miR-21：一种在高脂饮食小鼠中延缓重度肝病和肝细胞癌的治疗靶点 | Jagtap, U. | N/A | miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice | |
| 为什么我们有这么多兴奋性神经元？ | Wang, Q. | N/A | Why do we have so many excitatory neurons? | |
| Na+/K+-ATPase的生电性给高度活跃的尖峰细胞的计算带来了挑战。 | Weerdmeester, L. | N/A | The electrogenicity of the Na+/K+-ATPase poses challenges for computation in highly active spiking cells | |
| 超快速多器官蛋白质组学揭示了药物疗效和毒性的组织特异性机制 | Xiong, Y. | N/A | Ultra-Fast Multi-Organ Proteomics Unveils Tissue-Specific Mechanisms of Drug Efficacy and Toxicity | |
| 人类海马体中的正负视网膜拓扑编码 | Angeli, P. A. | N/A | Positive and Negative Retinotopic Codes in the Human Hippocampus | |
| 内在无序蛋白质在其构象集合中可以表现出不同的聚合物行为。 | Chakraborty, S. | N/A | Intrinsically disordered proteins can behave as different polymers across their conformational ensemble | |
| 针对神经纤毛蛋白-1增强黑色素瘤的免疫治疗：减少肿瘤进展及外周调节性T细胞介导的免疫抑制 | Khamaru, S. | N/A | Targeting Neuropilin-1 to Enhance Immunotherapy in Melanoma: Reducing Tumour Progression and Peripheral Treg-Mediated Immunosuppression | |
| 海盗：掠夺AlphaFold预测以自动化蛋白质工程 | Richardson, G. | N/A | PIRATE: Plundering AlphaFold Predictions to Automate Protein Engineering | |
| 一项针对具有形态多样解剖结构的人类主动脉CT图像的U-Net三维图像分割研究 | Chen, J. | N/A | A 3D Image Segmentation Study of U-Net on CT Images of the Human Aorta with Morphologically Diverse Anatomy | |
| 血生物化学变化及由北西埃塞俄比亚贡达ELFORA屠宰场屠宰绵羊的捻转血矛线虫病引起的病变特征 | Malede, B. A. | N/A | Haematobiochemical Alterations and Lesion Characterization Induced by Haemonchosis in Sheep Slaughtered at Gondar ELFORA Abattoir, North West Ethiopia | |
| HBN-EEG：健康大脑网络（HBN）脑电图数据集的FAIR实现 | Shirazi, S. Y. | N/A | HBN-EEG: The FAIR implementation of the Healthy Brain Network (HBN) electroencephalography dataset | |
| 研究早期儿童功能性和结构性脑网络架构、年龄与注意力技能之间的关系 | Rokos, L. | N/A | Examining Relationships between Functional and Structural Brain Network Architecture, Age, and Attention Skills in Early Childhood | |
| 在分枝杆菌中破坏核黄素生物合成，确立了5-氨基-6-D-核糖胺尿嘧啶（5-A-RU）作为MAIT细胞激动剂的关键前体。 | Chengalroyen, M. D. | N/A | Disruption of riboflavin biosynthesis in mycobacteria establishes 5-amino-6-D-ribitylaminouracil (5-A-RU) as key precursor of MAIT cell agonists | |
| 结构集合的弹性分析揭示了AAA+马达中手对手传递的能量基础 | Mello, V. H. | N/A | Elastic analysis of structural ensemble reveals the energetic basis of hand-over-hand in a AAA+ motor | |
| 用于特诺河大西洋鲑（Salmo salar）种群复合体高效遗传种群鉴定的单核苷酸多态性基因分型面板 | Johansson, H. | N/A | A single nucleotide polymorphism genotyping panel for efficient genetic stock identification of the Teno river Atlantic salmon (Salmo salar) population complex | |
| 应用模块化异恶唑啉-β2,2-氨基酸基肽模拟折叠体作为研究tau错误折叠机制的化学模型系统。 | Di Lorenzo, D. | N/A | Application of modular isoxazoline-β2,2-amino acid-based peptidomimetic foldamers as a chemical model system for studying the tau misfolding mechanism. | |
| 一个活性物质模型捕捉了形态发生过程中肌动蛋白-肌球蛋白振荡的空间动力学。 | Mackay, E. D. | N/A | An active matter model captures the spatial dynamics of actomyosin oscillations during morphogenesis | |
| 一种用于分析谷物中淀粉颗粒大小分布的曲线拟合方法 | McNelly, R. | N/A | A curve fitting method for analysing starch granule size distributions in cereals | |
| FIP 1.0数据集：高分辨率注释图像时间序列，包含在六年中种植的4000个小麦地块 | Roth, L. | N/A | The FIP 1.0 Data Set: Highly Resolved Annotated Image Time Series of 4,000 Wheat Plots Grown in Six Years | |
| 大麻和啤酒花中的FT样基因：性别特异性表达和拷贝数变异可能解释了开花时间的变异 | Dowling, C. A. | N/A | FT-like genes in Cannabis and hops: sex specific expression and copy-number variation may explain flowering time variation | |
| 增强生长的非生物素依赖型酿酒酵母：构建乙酰辅酶A羧化酶旁路 | Slanska, M. | N/A | Biotin-Independent Saccharomyces cerevisiae with Enhanced Growth: Engineering an Acetyl-CoA Carboxylase Bypass | |
| 运动想象超越想象中的动作，提升表现 | Gippert, M. | N/A | Motor Imagery Enhances Performance Beyond the Imagined Action | |
| 利用多组儿科临床睡眠数据洞察神经发育：儿科睡眠回顾性分析（RASP）队列研究 | Gong, N. N. | N/A | Leveraging clinical sleep data across multiple pediatric cohorts for insights into neurodevelopment: the Retrospective Analysis of Sleep in Pediatric (RASP) cohorts study | |
| 微生物生命树中质粒的缩放规律 | Maddamsetti, R. | N/A | Scaling laws of plasmids across the microbial tree of life | |
| 微生物生命树中质粒的缩放规律 | Maddamsetti, R. | N/A | Scaling laws of plasmids across the microbial tree of life | |
| 古菌信号网络——对产甲烷古菌Methanosarcina acetivorans中组氨酸激酶和响应调节蛋白结构与功能的新见解 | Georgiev, N. F. | N/A | Archaeal signalling networks - new insights into the structure and function of histidine kinases and response regulators of the methanogenic archaeon Methanosarcina acetivorans | |
| 一个普遍存在且多样化的产甲烷群落推动了富营养化沿海沉积物中的微生物甲烷循环。 | Wallenius, A. J. | N/A | A ubiquitous and diverse methanogenic community drives microbial methane cycling in eutrophic coastal sediments | |
| 黑素细胞分化和机械感觉受到不同细胞外基质蛋白的差异性调节 | Luthold, C. | N/A | Melanocyte differentiation and mechanosensation are differentially modulated by distinct extracellular matrix proteins | |
| 组蛋白乙酰转移酶CBP的依赖催化与不依赖催化的功能促进先驱因子介导的合子基因组激活 | Marsh, A. J. | N/A | Catalytic-dependent and independent functions of the histone acetyltransferase CBP promote pioneer factor-mediated zygotic genome activation | |
| α-古巴烯对亚洲柑橘木虱Diaphorina citri具有强烈的驱避作用。 | Magnani, R. F. | N/A | α-Copaene is a potent repellent against the Asian Citrus Psyllid Diaphorina citri | |
| 液滴微流控筛选用于工程化血管紧张素转换酶2（ACE2）的催化活性 | Okal, E. | N/A | Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity | |
| 利用无标签学习计算机视觉方法估算蜂鸟的拍翅频率 | Bastidas-Rodriguez, M. X. | N/A | Estimating wingbeat frequency on hummingbirds by using a no-labeling learning computer vision approach | |
| 染色质结构的异质性驱动B细胞急性淋巴母细胞白血病中的核心调控通路 | Sen, A. | N/A | Heterogeneity in chromatin structure drives core regulatory pathways in B-cell Acute Lymphoblastic Leukemia | |
| 通过植物中的激素运输实现对母体气候的跨代适应 | Chen, X. | N/A | Trans-generational adaptation to maternal climate through hormone transport in plants | |
| 睡眠剥夺与饮食对生长、认知、炎症、氧化应激及组织组织学影响的评估 | Usman, L. A. | N/A | ASSESSMENT OF THE IMPACT OF SLEEP DEPRIVATION AND DIET ON GROWTH, COGNITION, INFLAMMATION, OXIDATIVE STRESS, AND TISSUE HISTOLOGY | |
| 细菌和古菌中基因组重排的流行性与动态变化 | Martinez-Gutierrez, C. A. | N/A | Prevalence and Dynamics of Genome Rearrangements in Bacteria and Archaea | |
| 倒立水母（Cassiopea）中乙酰胆碱能对睡眠的调控 | Abrams, M. J. | N/A | Cholinergic regulation of sleep in the upside-down jellyfish Cassiopea | |
| 哺乳动物的胆汁酸化学感觉检测有助于物种和肠道微生物群的评估。 | Haran, V. | N/A | Mammalian chemosensory bile acid detection supports species and gut microbiome evaluation | |
| 单突触腹侧被盖区谷氨酸投射至蓝斑，增强厌恶情绪处理。 | Parker, K. E. | N/A | Monosynaptic ventral tegmental area glutamate projections to the locus coeruleus enhance aversive processing | |
| 通过强化学习，行为控制的大脑类神经动力学得以发展。 | Codol, O. | N/A | Brain-like neural dynamics for behavioral control develop through reinforcement learning | |
| 支撑人类意识的大脑网络的皮层下中枢 | Cambareri, M. K. | N/A | Subcortical Hubs of Brain Networks Sustaining Human Consciousness | |
| 运动皮层中言语思维的表征及其对言语神经假体的启示 | Kunz, E. M. | N/A | Representation of Verbal Thought in Motor Cortex and Implications for Speech Neuroprostheses | |
| Rho/Rok依赖的肌动肌球蛋白收缩性调控在三细胞连接处控制果蝇上皮通透性 | Jacobs, T. | N/A | Rho/Rok-dependent regulation of actomyosin contractility at tricellular junctions controls epithelial permeability in Drosophila | |
| 运动单位间抑制性输入的异质分布是运动适应疼痛的关键机制 | Hug, F. | N/A | Heterogeneous distribution of inhibitory inputs among motor units as a key mechanism for motor adaptations to pain | |
| 自动化、无压力且精确的鸣禽体重测量在神经科学实验中 | Bonneh, Y. | N/A | Automated, Stress-Free, and Precise Measurement of Songbird Weight in Neuroscience Experiments | |
| 神经群体动态的动态模型 | Hao, H. | N/A | Dynamic Models of Neural Population Dynamics | |
| 用于双光子亚细胞钙成像的预处理工具箱 | Jiang, A. | N/A | A preprocessing toolbox for 2-photon subcellular calcium imaging | |
| 研究健康和受损的人三叉神经中与神经性疼痛相关的细胞和分子变化 | Morchio, M. | N/A | Investigation of cellular and molecular changes linked with neuropathic pain in healthy and injured human trigeminal nerves | |
| 光遗传学激活丘脑网状核对小鼠睡眠结构的影响 | Arai, M. | N/A | Impact of Optogenetic Activation of the Thalamic Reticular Nucleus on Sleep Architecture in Mice | |
| 上丘投射驱动多巴胺神经元活动和运动，但不驱动价值 | Poisson, C. L. | N/A | Superior colliculus projections drive dopamine neuron activity and movement but not value | |
| 针对C9ORF72中致病性正义重复RNA的反义寡核苷酸能够抑制依赖反义链的二肽重复蛋白的产生，这些蛋白与ALS/FTD相关。 | Gu, Y. | N/A | Antisense oligonucleotide targeting pathogenic sense repeat RNA in C9ORF72 suppresses production of antisense-dependent dipeptide repeat proteins implicated in ALS/FTD | |
| 早期听觉和成年后的交配经历与鸣禽身份相互作用，塑造了雌性斑胸草雀对鸣唱的神经反应。 | Catalano, I. | N/A | Early auditory and adult mating experiences interact with singer identity to shape neural responses to song in female zebra finches | |
| 悬浮组织开放微流控图案化技术（STOMP） | Haack, A. J. | N/A | Suspended Tissue Open Microfluidic Patterning (STOMP) | |
| 生物膜形成的电生成动力学：枯草芽孢杆菌中基因表达与电化学活性之间的关联 | Yavarinasab, A. | N/A | Electrogenic Dynamics of Biofilm Formation: Correlation Between Genetic Expression and Electrochemical Activity in Bacillus subtilis | |
| 磷酸化对PRC1微管交联作用的影响探究 | Tai, E. | N/A | Insights into the role of phosphorylation on microtubule crosslinking by PRC1 | |
| 在临床扫描仪上使用神经突交换成像（NEXI）绘制的人类灰质微结构图 | Uhl, Q. | N/A | Human gray matter microstructure mapped using Neurite Exchange Imaging (NEXI) on a clinical scanner | |
| 人类和小鼠的Kabuki综合征模型揭示了抑制性突触发育的增加。 | Knopp, J. | N/A | Human and Mouse Models for Kabuki Syndrome Reveal Increase in Inhibitory Synapse Development. | |
| 海马长轴功能特化的成年寿命效应 | Bowman, C. | N/A | Adult lifespan effects on functional specialization along the hippocampal long axis | |
| 谨慎标记 - 蛋白质标记如何影响凝聚物的形成 | D/"orner, K. | N/A | Tag with Caution - How protein tagging influences the formation of condensates | |
| Siglec-F缺乏可预防博来霉素诱导的急性肺损伤后的纤维化 | Orlov, M. | N/A | Siglec-F Deficiency Prevents Fibrosis After Bleomycin-Induced Acute Lung Injury | |
| 跨物种保护表明，溶组织内阿米巴的吞噬作用通过转移补体激活的负调控因子实现了对补体的抵抗。 | Ruyechan, M. | N/A | Cross-species protection suggests Entamoeba histolytica trogocytosis enables complement resistance through the transfer of negative regulators of complement activation | |
| 肠道细菌编码的还原酶能够生物转化类固醇激素 | Arp, G. | N/A | Gut Bacteria Encode Reductases that Biotransform Steroid Hormones | |
| G3BP应激颗粒蛋白强化了整合应激反应的翻译程序 | Smith, J. | N/A | The G3BP Stress-Granule Proteins Reinforce the Translation Program of the Integrated Stress Response | |
| 揭示果蝇（Drosophila melanogaster）现有遗传变异中对寿命具有显著效应的位点及上位性 | van den Heuvel, J. | N/A | Uncovering large effect loci and epistasis for lifespan in standing genetic variation in the fruit fly Drosophila melanogaster | |
| LEU2和BAP2的共致死性依赖于碳源，并且在酿酒酵母中通过删除BUL1得以克服。 | S, M. | N/A | Co-lethality of LEU2 and BAP2 is carbon source dependent and is overcome by BUL1 deletion in Saccharomyces cerevisiae | |
| 定义基因组范围分析和群体数据库的串联重复目录及变异簇 | Weisburd, B. | N/A | Defining a tandem repeat catalog and variation clusters for genome-wide analyses and population databases | |
| 内在分子标识符能够在单细胞测序中实现稳健的分子计数 | Fontanez, K. | N/A | Intrinsic molecular identifiers enable robust molecular counting in single-cell sequencing | |
| 氨基-罗卡拉特增强eIF4A1 RNA夹合的结构基础 | Conley, J. F. | N/A | Structural Basis for the Improved RNA-Clamping of Amidino-Rocaglates to eIF4A1 | |
| Ixochymostatin，一种来自Ixodes scapularis的类胰蛋白酶抑制剂（TIL）蛋白，能够抑制糜蛋白酶并损害血管通透性。 | Almeida Martins, L. | N/A | Ixochymostatin, a trypsin inhibitor-like (TIL) protein from Ixodes scapularis, inhibits chymase and impairs vascular permeability | |
| 改进基于扩散的蛋白质骨架生成与全局几何感知潜在编码 | Zhang, Y. | N/A | Improving diffusion-based protein backbone generation with global-geometry-aware latent encoding | |
| FunCoup Cytoscape应用程序：多物种网络分析与可视化 | Buzzao, D. | N/A | The FunCoup Cytoscape App: multi-species network analysis and visualization | |
| 仿生和等离子体膜囊泡的形状分析 | Kudawla, R. | N/A | Shape analysis of biomimetic and plasma membrane vesicles | |
| 拉伸诱导肌球蛋白进入横向肌动蛋白环，稳定轴突大货物运输 | Rahman, N. | N/A | Stretch-induced recruitment of myosin into transversal actin rings stabilizes axonal large cargo transport | |
| 朝向精确、力场无关的内在无序蛋白质构象集合 | Borthakur, K. | N/A | Towards accurate, force field independent conformational ensembles of intrinsically disordered proteins | |
| 通过共价别构分子胶抑制NRF2依赖的癌症生长 | Roy, N. | N/A | Suppression of NRF2-dependent cancer growth by a covalent allosteric molecular glue | |
| 一种用于体外常温多脏器灌注平台开发的迭代设计方法 | van Leeuwen, L. L. | N/A | An iterative design approach to development of an ex-vivo normothermic multivisceral perfusion platform | |
| 全面测序哮喘诱导下肺神经免疫景观 | McSwiggin, H. | N/A | Comprehensive sequencing of the lung neuroimmune landscape in response to asthmatic induction | |
| C-反应蛋白通过激活补体系统，在肝脏中强力清除血液中的细菌 | Chen, D. | N/A | C-Reactive Protein Drives Potent Clearance of Blood Bacteria in the Liver by Activating the Complement System | |
| 通过使用大肠杆菌作为模型微生物，区分纳米铜和离子铜的抗菌机制 | Jose, G. P. | N/A | Differentiating the mechanism of antibacterial activities of nano and ionic copper by using Escherichia coli as a model microorganism | |
| 测试被子植物和苔藓物种生命阶段间冲突的基因组足迹 | Yuan, M. | N/A | Testing for the genomic footprint of conflict between life stages in an angiosperm and a moss species | |
| 种群大小对适应温度波动的影响 | Räsänen, E. | N/A | The effect of population size on adaptation to fluctuating temperatures | |
| 进化史中长期的营养不良会增强老年时期的病原体易感性。 | Sarkar, S. | N/A | Evolutionary history with chronic malnutrition enhances pathogen susceptibility at older ages | |
| 酵母氨基酸感应SEAC-EGOC超复合体的结构与功能 | Tafur, L. | N/A | Structure and function of the yeast amino acid-sensing SEAC-EGOC supercomplex | |
| 池塘伙伴：一种基于PageRank的池化方法，用于深度学习中鲁棒的蛋白质序列表示 | TARTICI, A. | N/A | Pool PaRTI: A PageRank-based Pooling Method for Robust Protein Sequence Representation in Deep Learning | |
| 人类无机磷酸盐出口蛋白XPR1的运输与InsP8激活机制 | Zhu, Q. | N/A | Transport and InsP8 activation mechanisms of the human inorganic phosphate exporter XPR1 | |
| ADT-1004：一种口服生物可利用的、选择性泛RAS抑制剂，用于胰腺导管腺癌的首创药物 | El-Rayes, B. N. | N/A | ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma | |
| 阿拉伯胶（阿拉伯胶树）以性别特异性和剂量依赖性的方式增强斑马鱼的繁殖并调节其微生物-肠道-大脑轴 | Abi Assaf, J. | N/A | Gum Arabic (Acacia senegal) enhances reproduction and modulates the microbiota-gut-brain axis of zebrafish in a sex-specific and dosage-dependent manner | |
| 深度挖掘人类抗体库可识别出频繁且免疫遗传多样化的CDRH3拓扑结构，这些结构可通过疫苗接种进行靶向。 | Habib, R. | N/A | Deep Mining of the Human Antibody Repertoire Identifies Frequent and Immunogenetically Diverse CDRH3 Topologies Targetable by Vaccination | |
| YY1的N端调节DNA和RNA对锌指结构域以及一个意外的核酸结合结构域的结合亲和力。 | Elias, J. | N/A | The N-terminus of YY1 regulates DNA and RNA binding affinity for both the zinc-fingers and an unexpected nucleic acid binding domain | |
| 温度诱导的膜运输驱动抗体向大脑的递送 | Du, F. | N/A | Temperature-induced membrane trafficking drives antibody delivery to the brain | |
| 核孔蛋白出口复合体的结构基础：RanBP2、SUMO1-RanGAP1、E2 Ubc9、Crm1与Ran GTPase之间的相互作用 | Baytshtok, V. | N/A | Structural basis for a nucleoporin exportin complex between RanBP2, SUMO1-RanGAP1, the E2 Ubc9, Crm1 and the Ran GTPase | |
| # BioRxiv 2024-10-04 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 如何利用转录组数据进行癌症细胞治疗诱导抗性的博弈论建模？基于患者来源的胶质母细胞瘤类器官的案例研究 | Spekking, L. | N/A | How to use transcriptomic data for game-theoretic modeling of treatment-induced resistance in cancer cells? A case study in patient-derived glioblastoma organoids | |
| 树突生长和突触组织受活动无关的线索和局部活动依赖性可塑性的调控。 | Kirchner, J. H. | N/A | Dendritic growth and synaptic organization from activity-independent cues and local activity-dependent plasticity | |
| 依赖于SAM的病毒MTase抑制剂：汉黄芩素和咖啡酸苯乙酯，对登革热MTase的结构洞察 | Bhutkar, M. | N/A | SAM-dependent viral MTase inhibitors: herbacetin and caffeic acid phenethyl ester, structural insights into dengue MTase | |
| 控制有限感知决策 | Castineiras de Saa, J. R. | N/A | Control Limited Perceptual Decision Making | |
| 新皮层电路振荡动力学的功能作用：一种计算视角 | Effenberger, F. | N/A | The functional role of oscillatory dynamics of neocortical circuits: a computational perspective | |
| 基底外侧杏仁核振荡在生物物理模型中实现恐惧学习 | Cattani, A. | N/A | Basolateral amygdala oscillations enable fear learning in a biophysical model | |
| 液-液界面限制能够再现体内中性粒细胞的形变，并引发基于囊泡的迁移。 | Schrope, J. H. | N/A | Confinement by liquid-liquid interface replicates in vivo neutrophil deformations and elicits bleb based migration | |
| 大规模皮层网络以结构化的循环方式组织。 | van Es, M. W. J. | N/A | Large-scale cortical networks are organized in structured cycles | |
| 通过脑桥网状结构进行运动控制的皮层-皮层下回路 | Bosz, E. | N/A | A cortico-subcortical loop for motor control via the pontine reticular formation | |
| 对小鼠集合淋巴管的细胞成分进行表征，结果显示淋巴肌肉细胞是调节淋巴收缩的固有起搏细胞。 | Zawieja, S. D. | N/A | Characterization of the cellular components of mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells regulating lymphatic contractions | |
| NPYR介导的调制是经验依赖性、性二态学习的基础 | Peedikayil-Kurien, S. | N/A | Modulation by NPYR underlies experience-dependent, sexually dimorphic learning | |
| 胰岛素和运动诱导的人类骨骼肌磷酸蛋白质组学研究揭示REPS1为肌肉葡萄糖摄取的新调控因子 | Kjaergaard, J. | N/A | Insulin and Exercise-induced Phosphoproteomics of Human Skeletal Muscle Identify REPS1 as a New Regulator of Muscle Glucose Uptake | |
| 撤回：飞蝗在躲避碰撞行为中的飞行肌协调与身体方向变化 | Manchester, C. W. | N/A | WITHDRAWN: Flight muscle coordination and body orientation changes of Locusta migratoria during collision avoidance behaviour | |
| 利用大型语言模型揭示人脑中的多层次和多模态语义表征 | Nakagi, Y. | N/A | Unveiling Multi-level and Multi-modal Semantic Representations in the Human Brain using Large Language Models | |
| 人类在自然噪声中对语音识别的敏感性，其基础在于中等水平声音统计的干扰。 | Clonan, A. C. | N/A | Interference of mid-level sound statistics underlie human speech recognition sensitivity in natural noise | |
| ADAMTS7促进动脉粥样硬化中的平滑肌泡沫细胞扩张 | Chung, A. | N/A | ADAMTS7 Promotes Smooth Muscle Foam Cell Expansion in Atherosclerosis | |
| 肝细胞RIPK1在代谢挑战期间维持肝脏稳态的作用 | Zhang, W. | N/A | Role of Hepatocyte RIPK1 in Maintaining Liver Homeostasis during Metabolic Challenges | |
| 多媒体：微生物组数据的多元中介分析 | Jiang, H. | N/A | multimedia: Multimodal Mediation Analysis of Microbiome Data | |
| 一项全基因组CRISPR筛选揭示了内体成熟蛋白WDR91作为黑色素瘤中有效ASO活性的促进因子 | Menchon, G. | N/A | A Genome-wide CRISPR screen unveils the endosomal maturation protein WDR91 as a promoter of productive ASO activity in melanoma | |
| 侧嗅皮层功能障碍在阿尔茨海默病小鼠中的表现 | Raghuraman, R. | N/A | Lateral Entorhinal Cortex Dysfunction in Alzheimer's Disease Mice | |
| 时空变换器用于解码神经运动控制 | Candelori, B. | N/A | Spatio-temporal transformers for decoding neural movement control | |
| 双层图学习揭示了乳腺癌多重数字病理学中与预后相关的肿瘤微环境模式 | Wang, Z. | N/A | Bi-level Graph Learning Unveils Prognosis-Relevant Tumor Microenvironment Patterns in Breast Multiplexed Digital Pathology | |
| 硅藻光系统I超复合物中岩藻黄素叶绿素a/c结合蛋白分子组装的结构基础 | Kato, K. | N/A | Structural basis for molecular assembly of fucoxanthin chlorophyll a/c-binding proteins in a diatom photosystem I supercomplex | |
| 青少年时期，大血管血流与微血管脑血管反应性在区域上是相互关联的。 | Zvolanek, K. M. | N/A | Macrovascular blood flow and microvascular cerebrovascular reactivity are regionally coupled in adolescence | |
| 小鼠感染拉科罗斯病毒后，中和抗体、细胞因子和趋化因子的年龄特异性动态变化 | Alatrash, R. | N/A | Age-specific dynamics of neutralizing antibodies, cytokines, and chemokines in response to La Crosse virus infection in mice | |
| 胎盘疟疾引发独特的甲基化模式，与胎儿生长受限相关 | Ozarslan, N. | N/A | Placental Malaria Induces a Unique Methylation Profile Associated with Fetal Growth Restriction | |
| 基于模型的力信号反卷积以估计在低、中和高力等长收缩下的运动单位抽搐参数 | Rohlen, R. | N/A | Model-based deconvolution of a force signal to estimate motor unit twitch parameters under low, moderate and high force isometric contractions | |
| 线粒体的动态变化支持了小胶质细胞表型的灵活性 | Espinoza, K. | N/A | Dynamic changes in mitochondria support phenotypic flexibility of microglia | |
| 元控制需求会抑制认知控制区域 | Akgur, B. F. | N/A | Meta-Control Demands Deactivate Cognitive-Control Regions | |
| 响应红光的Cre重组酶用于细菌的光遗传学 | Jafarbeglou, F. | N/A | Red light responsive Cre recombinase for bacterial optogenetics | |
| 蜂鸟传粉和自花传粉的猴面花（Mimulus）物种之间花部性状分化的遗传结构 | Chen, H. | N/A | The genetic architecture of floral trait divergence between hummingbird- and self-pollinated monkeyflower (Mimulus) species | |
| 不同的多巴胺能脉冲时序依赖可塑性规则适合不同的功能角色 | Sosis, B. | N/A | Distinct dopaminergic spike-timing-dependent plasticity rules are suited to different functional roles | |
| 左半球对元音的衰减处理预测了自闭症儿童在噪音环境中的语音感知缺陷 | Fadeev, K. A. | N/A | Attenuated processing of vowels in the left hemisphere predicts speech-in-noise perception deficit in children with autism | |
| 非遍历性和辛普森悖论在认知控制神经认知动力学中的体现 | Mistry, P. K. | N/A | Nonergodicity and Simpson's paradox in neurocognitive dynamics of cognitive control | |
| PA28γ通过提升线粒体功能，促进肿瘤的恶性进展，这一过程依赖于C1QBP。 | Wang, J. | N/A | PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP | |
| 在坦桑尼亚南部的一个下放野生动物管理区内，围绕授权渔业定居点建立了一个有效的社区保护模式。 | Duggan, L. M. | N/A | An effective model for community-based conservation around authorized fishing settlements inside a devolved Wildlife Management Area in southern Tanzania | |
| 通过Cre/loxP系统快速体外组装并转移DNA片段至JCVI-syn3B最小合成细菌基因组的方法 | Uenoyama, A. | N/A | Rapid in vitro method to assemble and transfer DNA fragments into the JCVI-syn3B minimal synthetic bacterial genome through Cre/loxP system | |
| 儿童中枢神经系统肿瘤中异常剪接的特征分析揭示CLK1为候选致癌依赖基因 | Naqvi, A. S. | N/A | Characterization of aberrant splicing in pediatric central nervous system tumors reveals CLK1 as a candidate oncogenic dependency | |
| 局部横向连接足以在深度神经网络中复制类似皮层的拓扑组织 | Qian, X. | N/A | Local lateral connectivity is sufficient for replicating cortex-like topographical organization in deep neural networks | |
| 循环网络中的状态表示学习：随机反馈和生物约束的力量 | Tsurumi, T. | N/A | Learning of state representation in recurrent network: the power of random feedback and biological constraints | |
| CRISP：相关性优化图像分割过程 | Briggs, J. | N/A | CRISP: Correlation-Refined Image Segmentation Process | |
| 确定抗生素的脱靶活性以及线粒体中新颖的翻译起始位点 | Marks, J. | N/A | Determining the off-target activity of antibiotics and novel translation initiation sites in mitochondria | |
| 揭示CRBN分子胶水隐藏的相互作用组：化学蛋白质组学研究 | Baek, K. | N/A | Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics | |
| 性发育、生长发育和营养依赖的大西洋鲑鱼主要成熟年龄基因表达 | Asheim, E. R. | N/A | Sex-, development-, and nutrition-dependent expression of a major age-at-maturity gene in Atlantic salmon | |
| 量化生物研究中条形图的数据失真 | Lin, T.-J. | N/A | Quantifying Data Distortion in Bar Graphs in Biological Research | |
| 光质信号的整合调控了幼苗建立过程中ABA含量和气孔运动 | Gustavsson, M. | N/A | Integration of light quality signals regulates ABA abundance and stomatal movements during seedling establishment | |
| 特定的序列特征会导致在检测多态性转座子插入时出现偏差。 | Verneret, M. | N/A | Particular sequence characteristics induce bias in the detection of polymorphic transposable element insertions | |
| 电磁刺激各向异性水凝胶用于引导神经形态发生 | Jensen, B. N. | N/A | Electromagnetic Stimulated Anisotropic Hydrogels for Guided Neuronal Morphogenesis | |
| CXXC指蛋白1与FOXP3相互作用，以稳定调节性T细胞的内稳态和抑制功能 | Meng, X. | N/A | CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells | |
| 鉴定与先天性心脏病中临床报告的CNV相关的长链非编码RNA候选疾病基因 | Penaloza, J. S. | N/A | Identification of Long Non-coding RNA Candidate Disease Genes Associated with Clinically Reported CNVs in Congenital Heart Disease | |
| 与满江红共培养对整株水稻代谢组的影响超越了传统无机氮肥的作用 | Consorti, E. | N/A | Co-cultivation with Azolla affects the metabolome of whole rice plant beyond canonical inorganic nitrogen fertilization | |
| 发育中的人类肺部空间解析蓝图揭示了一种由WNT驱动微环境调控的基底细胞群体 | Hsu, P. P. | N/A | A spatially-resolved blueprint of the developing human lung reveals a basal cell population regulated by a WNT-driven niche | |
| 一个针对环境16S rRNA牛津纳米孔测序数据分析的优化参考数据库 | Philip, M. | N/A | A Targeted Reference Database for Improved Analysis of Environmental 16S rRNA Oxford Nanopore Sequencing Data | |
| 在重构系统中20种氨酰-tRNA合成酶的可持续再生：迈向自合成人工系统的研究 | Hagino, K. | N/A | Sustainable Regeneration of 20 Aminoacyl-tRNA Synthetases in a Reconstituted System Toward Self-Synthesizing Artificial Systems | |
| 拟南芥RNA结合蛋白SGS3被招募到染色质重塑因子CHR11上，以促进从蛋白质编码基因中产生小干扰RNA（siRNA）。 | Elmayan, T. | N/A | The Arabidopsis RNA-binding protein SGS3 is recruited to the chromatin remodeler CHR11 to promote siRNA production from protein-coding genes | |
| 早期转移过程中力学生物学信号对骨细胞的调控驱动后续的骨质溶解：一个计算力学调控框架的预测 | Verbruggen, A. S. K. | N/A | Mechanobiological cues to bone cells during early metastasis drive later osteolysis: a computational mechanoregulation framework prediction | |
| 常规经颅直流电刺激（tDCS）和高清晰度经颅直流电刺激（HD-tDCS）对小脑的偏移镇痛作用的差异效应 | O'Connor, N. | N/A | Differential effects of conventional transcranial direct current stimulation (tDCS) and high-definition transcranial direct current stimulation (HD-tDCS) of the cerebellum on offset analgesia | |
| Meta2DB：为健康状态预测而精选的鸟枪法宏基因组特征集及元数据 | Kok, C. R. | N/A | Meta2DB: Curated Shotgun Metagenomic Feature Sets and Metadata for Health State Prediction | |
| 单脉冲和成对脉冲经颅磁刺激在人类近中央皮质中激活了空间上不同的皮质运动表征 | Madsen, M. A. J. | N/A | Single and paired TMS pulses engage spatially distinct corticomotor representations in human pericentral cortex | |
| 口服暴露于牛奶巴氏灭菌的HPAI H5N1对小鼠免疫反应和死亡率的影响 | Brigleb, P. H. | N/A | Effects of Oral Exposure to HPAI H5N1 Pasteurized in Milk on Immune Response and Mortality in Mice | |
| 一种利用生物层干涉技术测量纳米抗体结合动力学及基于竞争的表位定位的有效方法 | Bates, T. A. | N/A | An effective method of measuring nanobody binding kinetics and competition-based epitope mapping using biolayer interferometry | |
| 氧化应激与心血管疾病中钙调节蛋白关联的数据驱动性见解。 | Panday, N. | N/A | Data-driven insights into the association between oxidative stress and calcium-regulating proteins in cardiovascular disease. | |
| 三维重建技术实现了高效的大规模表型分析和叶序的定量遗传学研究。 | Davis, J. M. | N/A | 3D Reconstruction Enables High-Throughput Phenotyping and Quantitative Genetic Analysis of Phyllotaxy | |
| 通过拓扑高阶功能连接揭示精神分裂症中的整合-分离失衡 | Li, Q. | N/A | Unraveling Integration-Segregation Imbalances in Schizophrenia Through Topological High-Order Functional Connectivity | |
| 决策信心与结果变异性最佳调控超参数设置的不同方面 | Desender, K. | N/A | Decision Confidence and Outcome Variability Optimally Regulate Separate Aspects of Hyperparameter Setting | |
| 双语能力调节学龄前儿童执行功能发展：一项初步研究 | Sade, S. | N/A | Bilingualism Modulates Executive Function Development in Pre-School Aged Children: A Preliminary Study | |
| 欧洲积极自然未来的叙事 | D'Alessio, A. | N/A | Narratives for positive nature futures in Europe | |
| 分泌的精胺合成酶揭示了PGC1a诱导的前列腺癌生长抑制的旁分泌作用 | Schaub Clarigue, A. | N/A | Secreted spermidine synthase reveals a paracrine role for PGC1a-induced growth suppression in prostate cancer | |
| 自愿的预扫视注意和非自愿的外源性注意对对比度外观的相同双向调制 | Zhang, T. | N/A | Same bi-directional modulation of contrast appearance for voluntary presaccadic attention and involuntary exogenous attention | |
| 前额叶皮层的不规则神经兴奋可以抵消与年龄相关的海马体θ活动在空间记忆维持中的减少。 | Park, S.-E. | N/A | Aperiodic neural excitation of the prefrontal cortex offsets age-related decrease in hippocampal theta activity for spatial memory maintenance | |
| 糖原合酶激酶-3对于调节性T细胞的发育和功能至关重要。 | Kandasamy, M. | N/A | Glycogen synthase kinase-3 is essential for Treg development and function | |
| 保守的染色质调控因子控制秀丽隐杆线虫对胞内病原体的转录免疫反应 | Tecle, E. | N/A | Conserved chromatin regulators control the transcriptional immune response to intracellular pathogens in Caenorhabditis elegans | |
| 在分枝杆菌中破坏核黄素生物合成，确立了5-氨基-6-D-核糖氨基尿嘧啶（5-A-RU）作为MAIT细胞激动剂的关键前体。 | Chengalroyen, M. D. | N/A | Disruption of riboflavin biosynthesis in mycobacteria establishes 5-amino-6-D-ribitylaminouracil (5-A-RU) as key precursor of MAIT cell agonists | |
| 新型嵌套基因Aff3ir的破坏介导了小鼠中紊乱血流诱导的动脉粥样硬化 | He, S. | N/A | Disruption of the Novel Nested Gene Aff3ir Mediates Disturbed Flow-Induced Atherosclerosis in Mice | |
| 拟南芥花分生组织中生长素信号传导中的随机基因表达 | Kong, S. | N/A | Stochastic Gene Expression in Auxin Signaling in the Floral Meristem of Arabidopsis thaliana | |
| 减少覆盖范围的空间异质性可以提高狗类狂犬病疫苗接种的有效性。 | Ferguson, E. | N/A | Reducing spatial heterogeneity in coverage improves the effectiveness of dog vaccination against rabies | |
| 元生物中g型溶菌酶的进化：对免疫和消化适应性的见解 | Moroz, L. L. | N/A | Evolution of g-Type Lysozymes in Metazoa: Insights into Immunity and Digestive Adaptations | |
| 基于系统发育的模拟表明，在真核生物起源期间，未采样的分支对基因流推断的影响较小。 | Bernabeu, M. | N/A | Phylogeny-aware simulations suggest a low impact of unsampled lineages in the inference of gene flow during eukaryogenesis | |
| 亚端粒特异性凝聚染色质受三种不同的组蛋白修饰调控 | Osaki, M. | N/A | Subtelomere-specific condensed chromatin is regulated by three different histone modifications | |
| 人群数据中极端离群RNA表达模式揭示了在个体子集中偶发性基因过度激活及其共调控模块 | Xie, C. | N/A | Patterns of extreme outlier RNA expression in population data reveal sporadic over-activation of genes with co-regulated modules in subsets of individuals | |
| 利用等位基因失衡数量性状位点模型探究顺式作用基因调控的极限 | Seoighe, C. | N/A | Probing the limits of cis-acting gene regulation using a model of allelic imbalance quantitative trait loci | |
| 三维机械限制指导肌肉干细胞的命运和功能 | Park, G. | N/A | 3D mechanical confinement directs muscle stem cell fate and function | |
| 计算设计与评估用于可扩展邻近蛋白质组学的最佳诱饵集 | Kasmaeifar, V. | N/A | Computational design and evaluation of optimal bait sets for scalable proximity proteomics | |
| 可展开治疗性抗体的计算设计：高效遍历结合剂景观及逃逸突变的挽救 | Dreyer, F. A. | N/A | Computational design of developable therapeutic antibodies: efficient traversal of binder landscapes and rescue of escape mutations | |
| 更多细胞，高倍多重单细胞数据中的更多二聚体 | Howitt, G. | N/A | More cells, more doublets in highly multiplexed single-cell data | |
| 应激途径的镶嵌调控奠定了衰老细胞异质性的基础 | Avelar, R. A. | N/A | Mosaic Regulation of Stress Pathways Underlies Senescent Cell Heterogeneity | |
| 增强的弱监督千兆像素WSI训练池化技术提高了分类和病变定位效果 | Chen, C.-C. | N/A | Enhanced Pooling for Weakly Supervised Gigapixel WSI Training Improves Classification and Lesion Localization | |
| EGDiff：一种实验引导的扩散模型，用于蛋白质构象系综生成 | Liu, Y. | N/A | EGDiff: An Experiment-Guided Diffusion model for protein conformational ensemble generation | |
| 对福尔马林固定石蜡包埋（FFPE）组织进行单细胞RNA测序，在乳腺癌中鉴定出多纤毛细胞 | Gonzalez-Martinez, S. | N/A | Single-cell RNA sequencing on formalin-fixed and paraffin-embedded (FFPE) tissue identified multi-ciliary cells in breast cancer | |
| RUVBL1和RUVBL2是神经母细胞瘤中可药物干预的MYCN调节因子。 | Siaw, J. T. | N/A | RUVBL1 and RUVBL2 are druggable MYCN regulators in neuroblastoma. | |
| 源自患者的胶质母细胞瘤类器官作为实时模型，用于评估临床CAR-T细胞疗法的反应 | Logun, M. | N/A | Patient-derived glioblastoma organoids as real-time avatars for assessing responses to clinical CAR-T cell therapy | |
| 真正的海洋昆虫——奥氏棘虱（Echinophthirius horridus von Olfers, 1816）（虱目：棘虱科）的独特体表形态 | White, T. | N/A | Unique cuticular morphology of a truly marine insect, Echinophthirius horridus von Olfers, 1816 (Phthiraptera: Echinophthiriidae) | |
| 肌肉特异性Keap1缺失增强了肌肉力量生成，但并未能阻止小鼠因不活动导致的肌肉萎缩。 | Miranda, E. R. | N/A | Muscle-specific Keap1 deletion enhances force production but does not prevent inactivity-induced muscle atrophy in mice | |
| 一项多组学普查揭示了与肥胖相关的微小RNA miR-let-7作为脂肪线粒体功能障碍和代际代谢衰退的新型引发因素。 | Huang, C. | N/A | A multi-omics census reveals obesity-associated microRNA miR-let-7 as novel instigator of adipose mitochondrial dysfunction and of intergenerational metabolic decline. | |
| H+ 驱动超快根对根响应伤口 | Ducla, J. | N/A | H+ drives ultra-fast root-to-root responses to wounding | |
| 通过MPK6磷酸化实现对MYC2的靶向降解揭示了JA信号传导的机制和意义 | Han, K.-H. | N/A | Targeted Degradation of MYC2 through MPK6 Phosphorylation Reveals Mechanisms and Implications for JA Signaling | |
| 扩展的底物范围交叉手性连接法实现了长L-RNA的高效合成 | Han, X. | N/A | An Expanded Substrate Scope for Cross-Chiral Ligation Enables Efficient Synthesis of Long L-RNAs | |
| 基于计算模型的细菌二硝基甲苯传感器设计 | Bahiri Elitzur, S. | N/A | Design of bacterial DNT sensors based on computational models | |
| 噪声生物系统的数据驱动模型发现与模型选择 | Wu, X. | N/A | Data-driven model discovery and model selection for noisy biological systems | |
| 自噬、泛素蛋白酶体系统和MAPK通路控制突触生长的温度依赖性。 | De Leon, K. | N/A | Autophagy, the Ubiquitin proteasome system, and the MAPK pathway control the temperature dependence of synaptic growth. | |
| 在灵长类动物腹侧前运动皮层中时间感知期间的情境神经动力学 | Diaz, H. | N/A | Contextual Neural Dynamics During Time Perception in Primate Ventral Premotor Cortex | |
| 使用合成轴突形态生成全脑连接组 | Petkantchin, R. | N/A | Generating brain-wide connectome using synthetic axonal morphologies | |
| 猕猴扣带皮层中的冲突神经元 | Corrigan, B. W. | N/A | Conflict neurons in cingulate cortex of macaques | |
| 阿尔茨海默病中与脑血管损伤和β-淀粉样蛋白并行的神经炎症通路 | Rizvi, B. | N/A | Parallel neuroinflammatory pathways to cerebrovascular injury and amyloid-beta in Alzheimer's disease | |
| 多感官伽马刺激增强了成年神经发生，并在唐氏综合症小鼠模型中改善了认知功能。 | Islam, M. R. | N/A | Multisensory gamma stimulation enhances adult neurogenesis and improves cognitive function in a mouse model of Down syndrome | |
| 一项关于脊髓损伤即时后果的药理学调控的电生理学研究揭示了TRPV4拮抗作用的关键作用。 | Mohammadshirazi, A. | N/A | An electrophysiological study about the pharmacological manipulation of the immediate consequences of a spinal trauma reveals a crucial role for TRPV4 antagonism. | |
| 秀丽隐杆线虫连接组中的双侧对称性与不对称性：基于冗余度测量的图论分析 | Kim, P. S. | N/A | Bilateral Symmetry and Asymmetry in the C. elegans Connectome: A Graph-Theoretic Analysis based on Redundancy Measures | |
| 神经运动生成的背后空间和网络原理 | Komi, S. | N/A | Spatial and network principles behind neural generation of locomotion | |
| 前视区谷氨酸能神经元对快速眼动睡眠起始和稳态的调控 | Mondino, A. | N/A | Regulation of REM Sleep Onset and Homeostasis by Preoptic Glutamatergic Neurons | |
| 达成一致：fMRI-超扫描揭示了双人组在心理状态空间中探索以协调意见。 | Speer, S. P. | N/A | Finding Agreement: fMRI-hyperscanning reveals that dyads explore in mental state space to align opinions. | |
| APOE通过抑制中性粒细胞胞外陷阱的产生，保护机体免受结核分枝杆菌严重感染。 | Liu, D. | N/A | APOE Protects Against Severe Infection with Mycobacterium tuberculosis by Restraining Production of Neutrophil Extracellular Traps | |
| 肺部CD4+驻留记忆T细胞利用气道分泌细胞来刺激和调节中性粒细胞性过敏性气道疾病。 | Ravi, V. R. | N/A | Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate neutrophilic allergic airways disease. | |
| 针对丙型肝炎病毒E1E2包膜糖蛋白的双特异性抗体 | Radic, L. | N/A | Bispecific antibodies against the hepatitis C virus E1E2 envelope glycoprotein | |
| 普遍规律支配着质粒拷贝数 | Ramiro-Martinez, P. | N/A | Universal rules govern plasmid copy number | |
| 加热处理改变了野生蓝莓土壤中细菌多样性和组成的时序动态。 | Alaba, O. | N/A | Warming treatments shift the temporal dynamics of diversity and composition of bacteria in wild blueberry soils. | |
| 来自肠道细菌的D-乳酸通过驱动赖氨酸D-乳酸化来调节肝脏细胞的转录 | Zang, Y. | N/A | D-lactate derived from intestinal bacteria drives lysine D-lactylation to modulate transcription in liver cells | |
| 聚合酶θ介导的末端连接的细胞周期调控是其对BLM-DNA2缺失敏感性的基础 | McBrine, C. P. | N/A | Cell cycle regulation of polymerase theta mediated end-joining underlies its sensitivity to loss of BLM-DNA2 | |
| 顺式调控元件之间的协同作用可以使凝聚蛋白对于远端增强子功能变得可有可无。 | Hansen, K. L. | N/A | Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function | |
| 秀丽隐杆线虫中Sjögrens综合征核抗原1的同源物对于维持中心粒的结构完整性和双极有丝分裂纺锤体的组装是必需的。 | Pfister, J. A. | N/A | The C. elegans homolog of Sjögrens Syndrome Nuclear Antigen 1 is required for the structural integrity of the centriole and bipolar mitotic spindle assembly | |
| VAPA介导利什曼原虫亚马逊种与宿主巨噬细胞之间的脂质交换。 | Gdovinova, I. | N/A | VAPA mediates lipid exchange between Leishmania amazonensis and host macrophages | |
| EASI-ORC：一种用于酵母细胞器-RNA共定位测量中高效分析和分割smFISH图像的管道 | Garin, S. | N/A | EASI-ORC: A Pipeline for the Efficient Analysis and Segmentation of smFISH Images for Organelle-RNA Colocalization Measurements in Yeast | |
| 解析单细胞中自主酶的变异性 | Gnann, C. | N/A | Dissecting autonomous enzyme variability in single cells | |
| 一种体外有丝分裂后的鼠类作为肌肉损伤和修复的模型 | Galluccio, A. | N/A | A post-mitotic in vitro murine as a model of muscle damage and repair | |
| A-C连接子控制着中心粒的粘附和复制。 | Bournonville, L. | N/A | The A-C Linker controls centriole cohesion and duplication | |
| ATAD2通过HIRA/组蛋白H3.3依赖的机制驱动染色质动态变化。 | Liakopoulou, A. | N/A | ATAD2 drives HIRA/histone H3.3-dependent chromatin dynamics | |
| 内皮细胞PROX1诱导中枢神经系统血脑屏障破坏 | Gonzalez Hernandez, S. | N/A | ENDOTHELIAL PROX1 INDUCES BLOOD-BRAIN BARRIER DISRUPTION IN THE CENTRAL NERVOUS SYSTEM | |
| 斑马鱼的种质稳定性需要母源的Tdrd6a和Tdrd6c | Consorte, A. | N/A | Germplasm stability in zebrafish requires maternal Tdrd6a and Tdrd6c | |
| 分析受保护与未受保护潮池的生物多样性 | Chen, V. | N/A | Analyzing Biodiversity in Protected vs. Unprotected Tide Pools | |
| 通过将基因表达建模为二元性状，量化系统发育上的转录组周转 | Thompson, A. | N/A | Quantifying transcriptome turnover on phylogenies bymodeling gene expression as a binary trait | |
| 二倍体有性生殖种群中的固定概率 | Shi, Z. | N/A | Fixation probability in a diploid sexually reproducing population | |
| 瑞典牛品种的人口历史：估计与模型检验 | Adepoju, D. | N/A | Population history of Swedish cattle breeds: estimates and model checking | |
| 雌性生殖系特异性蛋白Sakura与Otu相互作用，对生殖干细胞的更新和分化以及卵子发生至关重要。 | Azlan, A. | N/A | Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis | |
| 基于k-mer的小麦集合全基因组关联分析揭示了白粉病抗性的新来源和多样性 | Jaegle, B. | N/A | k-mer-based GWAS in a wheat collection reveals novel and diverse sources of powdery mildew resistance | |
| 一种基于基因型的方法识别了犬类中的腭裂和其他表型的变异 | Buckley, R. M. | N/A | A genotype-first approach identifies variants for orofacial clefts and other phenotypes in dogs | |
| 定量蛋白质组质谱法分析蛋白激酶以确定人类激酶组的动态异质性 | East, M. P. | N/A | Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome | |
| 尼帕病毒复制的结构基础 | Sala, F. A. | N/A | Structural basis of Nipah virus replication | |
| 重复基因组区域中的长片段缺失签名记录了体细胞进化，并能够敏感地检测微卫星不稳定性。 | Guo, Q. | N/A | Long deletion signatures in repetitive genomic regions track somatic evolution and enable sensitive detection of microsatellite instability | |
| 整合生物信息学与人工智能方法以识别影响蛋白质稳定性和功能的破坏性STAT1变异体 | Kamal, E. | N/A | Integrating Bioinformatics and Artificial Intelligence Methods to identify disruptive STAT1 variants impacting Protein Stability and Function | |
| 基于深度学习的主要组织相容性复合体中的基序发现：入门指南 | Alvarez, B. | N/A | Deep Learning-Based Motif Discovery in MajorHistocompatibility Complex: A Primer | |
| 一个基于浏览器的平台，用于在HPC环境中存储、可视化和分析大规模的3D图像。 | Walker, L. A. | N/A | A browser-based platform for storage, visualization, and analysis of large-scale 3D images in HPC environments | |
| 基于优化后的蓝图进行ATP酶的从头设计，该蓝图适用于容纳P-loop基序 | Kosugi, T. | N/A | De novo design of ATPase based on the blueprint optimized for harboring the P-loop motif | |
| 超越平面：鱼群在三维空间中采用梯形编队 | Ko, H. | N/A | Beyond planar: fish schools adopt ladder formations in 3D | |
| 结构集合的弹性分析揭示了AAA+马达中手对手传递的能量基础 | Mello, V. H. | N/A | Elastic analysis of structural ensemble reveals the energetic basis of hand-over-hand in a AAA+ motor | |
| 生物膜流丝的应力硬化行为 | Savorana, G. | N/A | Stress-hardening behaviour of biofilm streamers | |
| 计算分析Nitazene衍生物在μ-阿片受体上的结合姿态 | Clayton, J. | N/A | Computational Analysis of the Binding Poses of Nitazene Derivatives at the mu-Opioid Receptor | |
| 力学约束组织三维组织并协调肌肉分化 | Nagle, I. | N/A | Mechanical constraints organize 3D tissues and orchestrate muscle differentiation | |
| APC协调GSK3对SETD8的磷酸化，以抑制结直肠癌 | Cramer, Z. | N/A | APC coordinates GSK3 phosphorylation of SETD8 to suppress colorectal cancer | |
| 时间多模态单细胞分析揭示了CAR-T细胞与胶质母细胞瘤的动态相互作用及对抗原阴性肿瘤细胞的靶向作用 | Zhang, D. Y. | N/A | Temporal multi-modal single-cell analyses reveal dynamic interactions of CAR-T cells with glioblastoma and targeting of antigen-negative neoplastic cells | |
| STAT1与YAP1之间的正反馈环路刺激脂质生物合成，加速突变型KRAS结直肠癌细胞的生长，并促进化疗耐药性。 | Wang, S. | N/A | A feedforward loop between STAT1 and YAP1 stimulates lipid biosynthesis, accelerates tumor growth, and promotes chemotherapy resistance in mutant KRAS colorectal cancer. | |
| 一种新的空间多组学方法，通过单个组织切片深入表征人类癌症组织 | Adimi, Y. | N/A | A new spatial multi-omics approach to deeply characterize human cancer tissue using a single tissue section | |
| 降雨对田间条件下空气中小麦锈菌孢子昼夜周期性的破坏作用 | Suffert, F. | N/A | Disruptive effect of rainfalls on the diurnal periodicity of airborne wheat rust spore under field conditions | |
| 系统遗传学解析阿尔茨海默病大脑基因表达网络 | Zhao, P. | N/A | Systems genetic dissection of Alzheimer's disease brain gene expression networks | |
| 基于深度学习的图像分类揭示了病毒感染期间细胞死亡命运的异质性执行 | Centofanti, E. | N/A | Deep learning-based image classification reveals heterogeneous execution of cell death fates during viral infection | |
| 建模上皮-间质转化（EMT）的动力学揭示了与泛癌中间状态和可塑性相关的基因 | McDermott, M. | N/A | Modeling the dynamics of EMT reveals genes associated with pan-cancer intermediate states and plasticity | |
| 发现具有切换无限GPFA的时序组合神经流形 | Yu, C. | N/A | Discovering Temporally Compositional Neural Manifolds with Switching Infinite GPFA | |
| Shank3B-/-小鼠中前额叶皮层（mPFC）PV中间神经元早期产后功能障碍 | Peixoto, R. T. | N/A | Early Postnatal Dysfunction of mPFC PV Interneurons in Shank3B-/- Mice | |
| 神经甾体敏感的δ-GABAA受体对成年小鼠味觉岛叶皮层甜味偏好的调节作用 | Yevoo, P. E. | N/A | Modulation of sweet preference by neurosteroid-sensitive, δ-GABAA receptors in adult mouse gustatory insular cortex | |
| JN.1加强疫苗对SARS-CoV-2变异株KP.3.1.1和XEC的中和作用影响 | Arora, P. | N/A | Impact of JN.1 booster vaccination on neutralisation of SARS-CoV-2 variants KP.3.1.1 and XEC | |
| CMTM4是一种粘附调节因子，调控海胆胚胎中骨骼模式形成和初级间充质细胞迁移。 | Descoteaux, A. E. | N/A | CMTM4 is an adhesion modulator that regulates skeletal patterning and primary mesenchyme cell migration in sea urchin embryos | |
| 土壤pH值影响感染个体宿主的噬菌体群落的组成 | Lee, S. | N/A | Soil pH influences the composition of bacteriophage communities infecting individual hosts | |
| 一个统一的理论框架，用于解释不同尺度下围栏实验结果的矛盾，以评估蜱传疾病的风险 | Freedman, A. S. | N/A | A unifying theoretical framework for tick-borne disease risk to explain conflicting results of exclosure experiments across scales | |
| 在感染野生禾本科植物的真菌物种中，种间杂交作为附加染色体起源的途径 | Fagundes, W. C. | N/A | Interspecies hybridization as a route of accessory chromosome origin in fungal species infecting wild grasses | |
| 规模化衰老：来自狗衰老项目的年轻犬只和大型犬种显示出加速的表观遗传衰老。 | McCoy, B. M. | N/A | Aging at scale: Younger dogs and larger breeds from the Dog Aging Project show accelerated epigenetic aging. | |
| 通过计算机分析和体外功效研究探索锦葵色素和芍药花色素作为潜在抗利什曼原虫药物的潜力 | Goyzueta-Mamani, L. D. | N/A | Exploring the Potential of Malvidin and Echiodinin as Probable Antileishmanial Agents Through In Silico Analysis And In Vitro Efficacy | |
| 通过对比对抗开放集域适应实现单细胞数据整合与细胞类型注释 | Aminzadeh, F. | N/A | Single-Cell Data Integration and Cell Type Annotation through Contrastive Adversarial Open-set Domain Adaptation | |
| 辉瑞-生物技术与莫德纳新冠疫苗中脂质纳米颗粒的比较分析：来自分子动力学模拟的洞察 | Biswal, M. R. | N/A | Comparative Analysis of Lipid Nanoparticles in Pfizer-BioNTech and Moderna COVID-19 Vaccines: Insights from Molecular Dynamics Simulations | |
| 在限制压力下三维菌落中应激响应细菌的生长 | Rahbar, S. | N/A | Growth of Stress-Responsive Bacteria in 3D Colonies under Confining Pressure | |
| SATB2和circ3915 RNA的染色质失调驱动了类似KRAS的致癌转化 | Eleazer, R. | N/A | SATB2 and circ3915 RNA chromatin dysregulation drive KRAS-like oncogenic transformation | |
| 来自白垩纪缅甸琥珀的一个显著的缨翅目家族，Miralidae stat. nov.（= Dinglidae syn. nov.；半翅目：胸喙亚目） | Ivanov, G. | N/A | A remarkable psyllomorph family from Cretaceous Burmese amber, Miralidae stat. nov. (= Dinglidae syn. nov.; Hemiptera: Sternorrhyncha) | |
| 扰动诱发皮层活动的重测信度反映了反应性平衡控制中稳定的个体差异 | Mirdamadi, J. L. | N/A | Test-retest reliability of perturbation-evoked cortical activity reflects stable individual differences in reactive balance control | |
| SPLASH-structure：一种从原始测序数据中识别RNA二级结构的统计方法，无需进行多序列比对 | Wang, J. F. | N/A | SPLASH-structure: a statistical approach to identify RNA secondary structures from raw sequencing data, bypassing multiple sequence alignment | |
| Latexin通过促进平滑肌细胞增殖和巨噬细胞迁移来促进新生内膜的形成。 | Kazama, K. | N/A | Latexin facilitates neointimal formation via promoting smooth muscle cell proliferation and macrophage migration | |
| # BioRxiv 2024-10-03 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 肿瘤细胞-脂肪细胞间隙连接激活脂肪分解，并促进乳腺癌的发生 | Williams, J. | N/A | Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis | |
| 气味通过果蝇的味觉受体神经元驱动进食。 | Wei, H.-p. | N/A | Odors drive feeding through gustatory receptor neurons in Drosophila | |
| 超声波抑制SARS-CoV-2体外感染性 | Veras, F. P. | N/A | Ultrasound inhibits SARS-CoV-2 infectivity in vitro | |
| 人类自噬起始ULK1C:PI3KC3-C1超复合物的结构与激活 | Chen, M. | N/A | Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex | |
| TIM-4 识别表达 RORγT 驱动的促炎细胞因子模块的效应 B 细胞，促进免疫应答 | Ding, Q. | N/A | TIM-4 Identifies Effector B cells Expressing a RORγT-driven Proinflammatory Cytokine Module That Promotes Immune responsiveness | |
| 打开物种箱：简约的微观物种形成模型对宏观进化的启示 | Couvert, E. | N/A | Opening the species box: What parsimonious microscopic models of speciation have to say about macroevolution | |
| 可解释的多尺度结构保留单细胞RNA测序数据嵌入模型 | Novak, D. | N/A | Interpretable models for scRNA-seq data embedding with multi-scale structure preservation | |
| 通过体内注射和电穿孔裸露mRNA恢复患有少弱畸精子症小鼠的精子生育力 | Vilpreux, C. | N/A | Sperm fertility restoration in mice suffering from oligo-astheno-teratozoospermia by in vivo injection and electroporation of naked mRNA | |
| 共享的句法和形态结构神经计算：来自汉语普通话的证据 | Yu, X. | N/A | Shared neural computations for syntactic and morphological structures: evidence from Mandarin Chinese | |
| HairSplitter：从长且有噪声的读取中进行单体型组装 | Faure, R. | N/A | HairSplitter: haplotype assembly from long, noisy reads | |
| 从BioModels中筛选模型：开发创建OMEX文件的工作流程 | Xu, J. | N/A | Curating models from BioModels: Developing a workflow for creating OMEX files | |
| 内侧前额叶皮层的特定层次输入与应激易感性相关 | Solakoglu, S. T. | N/A | Layer-specific input to medial prefrontal cortex is linked to stress susceptibility | |
| 纹状体脑片中持续活动模式对多巴胺释放的调控 | Boumhaouad, S. | N/A | Regulation of dopamine release by tonic activity patterns in the striatal brain slice | |
| 整合跨振荡功率频段的数据可预测癫痫病灶区：频率范围探索癫痫病灶区（FREEZ）识别算法 | O'Leary, S. | N/A | Integrating Data Across Oscillatory Power Bands Predicts the Epileptogenic Zone: the Frequency Range Explorer Epileptogenic Zone (FREEZ) Identification Algorithm | |
| 佐剂递送方法及纳米颗粒电荷对肽酰胺微泡疫苗生物活性的影响 | Zhang, R. | N/A | Adjuvant Delivery Method and Nanoparticle Charge Influence Peptide Amphiphile Micelle Vaccine Bioactivity | |
| 两栖动物基因组学联盟：推动两栖动物研究与保护的基因组学和遗传资源发展 | Kosch, T. A. | N/A | The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation | |
| 高度相似的氯代烷烃还原脱卤酶的动力学对比 | Picott, K. | N/A | Contrasting kinetics of highly similar chloroalkane reductive dehalogenases | |
| 行走于蜿蜒小径时的侧向不稳定性概率 | Render, A. C. | N/A | Probability of Lateral Instability While Walking on Winding Paths | |
| 流感病毒感染经历会改变肺部结构细胞的动态，从而在病毒再次攻击后迅速获得免疫保护。 | Worrell, J. C. | N/A | Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge | |
| 小说口头指令招募了时间变量信息维度抽象神经模式 | Pena, P. | N/A | Novel verbal instructions recruit abstract neural patterns of time-variable information dimensionality | |
| 评估AEV01在胶质瘤和肝细胞癌中的抗肿瘤疗效及安全性：体外和体内研究方法。 | Biswas, I. | N/A | Evaluating the Anti-tumor efficacy and safety of AEV01 in Glioma and Hepatocellular Carcinoma: An In Vitro and In Vivo approach. | |
| 皮质醇动态变化及斑马鱼幼体暴露于重复应激下的糖皮质激素受体依赖性反馈调节 | Castillo-Ramirez, L. A. | N/A | Cortisol dynamics and GR-dependent feedback regulation in zebrafish larvae exposed to repeated stress | |
| 气候变化、农药和药物对孔雀鱼（Nothobranchius furzeri）生命史和行为综合影响的研究 | Kim, D. | N/A | The combined impact of climate change, pesticides and pharmaceuticals on life history and behaviour in killifish (Nothobranchius furzeri) | |
| 多巴胺与时间折扣：重新审视药理学与个体差异 | Smith, E. | N/A | Dopamine and temporal discounting: revisiting pharmacology and individual differences | |
| 大小-重量错觉及其超越：一种感知重量的新模型 | Pisu, V. | N/A | The size-weight illusion and beyond: a new model of perceived weight | |
| 一种新的Betaflexivirus属病毒在Ferraria crispa植物中被发现 | Dekker, R. J. | N/A | A new Betaflexivirus species in Ferraria crispa plants | |
| 在Lachenalia植物中发现的新型Phenuivirus物种揭示了5'和3' RNA序列基序之间可能的协同进化 | Dekker, R. J. | N/A | Discovery of a new Phenuivirus species in Lachenalia plants reveals possible co-evolution between 5' and 3' RNA sequence motifs | |
| 结构蛋白质组学揭示了孕酮受体的顺序启动机制 | Mann, M. D. | N/A | Structural proteomics defines a sequential priming mechanism for the progesterone receptor | |
| 人类视觉皮层在准备期间的双格式注意模板 | Chen, Y. | N/A | Dual-format attentional template during preparation in human visual cortex | |
| 缺失但未受糖皮质激素调节的促肾上腺皮质激素释放激素（Crh）调控小鼠的焦虑样行为 | Friedman, H. R. | N/A | Absent, but not glucocorticoid-modulated, corticotropin-releasing hormone (Crh) regulates anxiety-like behaviors in mice | |
| Lumen电荷调控β-桶状纳米孔中的忆阻离子传输 | Mayer, S. F. | N/A | Lumen charge governs memristive ion transport in β-barrel nanopores | |
| 调节秀丽隐杆线虫进入持久幼虫状态决策的神经元活动 | Prakash, S. J. | N/A | Neuronal activity regulating the dauer entry decision in Caenorhabditis elegans | |
| RAPDOR：利用Jensen-Shannon距离进行复杂蛋白质组学数据集的计算分析 | Hemm, L. | N/A | RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets | |
| 经验塑造了嗅觉表征沿着皮层-海马路径的转变 | Schiltz, E. | N/A | Experience shapes the transformation of olfactory representations along the cortico-hippocampal pathway | |
| RNA结合蛋白Musashi1与病毒基因组RNA相互作用，并通过抑制翻译来限制SARS-CoV-2感染。 | Ganguli, S. | N/A | RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translation | |
| 阿塔卡马沙漠的土壤生物多样性在不同多样性水平上呈现出明显的模式。 | Villegas, L. | N/A | Soil biodiversity in the Atacama Desert shows distinct patterns at different diversity levels | |
| ClassiCOL：通过胶原蛋白肽模糊性进行古代物种分类的LC-MS/MS分析 | Engels, I. | N/A | ClassiCOL: LC-MS/MS analysis for ancient species Classification via Collagen peptide ambiguation | |
| 从太平洋牡蛎中分离得到的Gallaecimonas pentaromativorans菌株10A的基因组显示了其降解碳氢化合物和CRISPR-Cas防御的潜力。 | Gouin, Y. | N/A | The genome of Gallaecimonas pentaromativorans strain 10A, isolated from a Pacific oyster, reveals the potential for hydrocarbon degradation and CRISPR-Cas defense | |
| 基于转录组的全基因组长非编码RNA（lncRNA）在冈比亚按蚊中的鉴定 | Xu, J. | N/A | Transcriptome-based identification of long noncoding RNAs (lncRNAs) across the genome of Anopheles gambiae | |
| 开发并验证一种计算工具，用于预测高级别浆液性卵巢癌患者细胞的治疗结果 | Cortesi, M. | N/A | Development and validation of a computational tool to predict treatment outcomes in cells from High-Grade Serous Ovarian Cancer patients | |
| 利用全基因组代谢网络分析神经发育，研究自闭症谱系障碍中的细胞代谢功能障碍 | Pourmajidian, M. | N/A | Investigation of cell metabolism dysfunction in autism spectrum disorders using genome-scale metabolic network analysis of neuronal development | |
| 期望引发音乐引发的寒颤 | de Fleurian, R. | N/A | Expectation elicits music-evoked chills | |
| 亲社会奖励与言语接收阈值相关，而年龄与噪声中言语感知的主观评分相关。 | Oakeson, R. J. | N/A | Prosocial reward relates to speech reception thresholds and age relates to subjective ratings of speech perception in noise | |
| 常染色体显性额颞叶痴呆临床表现中的性别差异 | Memel, M. | N/A | Sex differences in the clinical manifestation of autosomal dominant frontotemporal dementia | |
| 雷帕霉素免疫调节利用时间依赖性的淋巴结结构改变、白细胞迁移和肠道微生物群的变化 | Wu, L. | N/A | Rapamycin Immunomodulation Utilizes Time-Dependent Alterations of Lymph Node Architecture, Leukocyte Trafficking, and Gut Microbiome | |
| 在产前暴露于较高水平母体炎症的中年/老年成人中，海马神经突密度降低 | Mohyee, R. A. | N/A | Decreased hippocampal neurite density in middle-aged/aging adults following prenatal exposure to higher levels of maternal inflammation | |
| 全球木本植物群落的代谢生长机制与理论生长潜力 | Shu, S. | N/A | Metabolic growth mechanisms and theoretical growth potential of global woody plant communities | |
| 水生食物对小岛屿发展中国家人类营养摄入和充足性的贡献 | Zamborain-Mason, J. | N/A | The contribution of aquatic foods to human nutrient intake and adequacy in a Small Island Developing State | |
| BCL-xL复合物尾部锚定对BH3-in-沟槽相互作用的全局调节限制了BH3模拟拮抗作用。 | Maillet, L. | N/A | Allosteric regulation of BH3-in-groove interactions by tail anchors of BCL-xL complexes limits BH3 mimetic antagonism. | |
| 细胞内核周β-肾上腺素受体在定义信号分隔和病理心脏重塑中的独特作用 | Turcotte, M. G. | N/A | The Unique Role of Intracellular Perinuclear β-Adrenergic Receptors in defining Signaling Compartmentation and Pathological Cardiac Remodeling | |
| 部分共享的多模态嵌入学习细胞状态的整体表示 | Zhang, X. | N/A | Partially Shared Multi-Modal Embedding Learns Holistic Representation of Cell State | |
| 使用新型荧光HPLC法量化小GTP酶的激活状态 | Araki, M. | N/A | Quantifying small GTPase activation status using a novel fluorescence HPLC-based assay | |
| GLA-3介导秀丽隐杆线虫生殖细胞中的应激反应：Tristetraprolin（TTP）家族的关键作用 | Salinas, L. S. | N/A | GLA-3 Mediates Stress Response in Caenorhabditis elegans Germ Cells: A key role of the Tristetraprolin (TTP) Family | |
| 一种可诱导且可逆的系统，用于调控秀丽隐杆线虫中不饱和脂肪酸的生物合成 | Battista, B. | N/A | An inducible and reversible system to regulate unsaturated fatty acid biosynthesis in C. elegans | |
| 胶质母细胞瘤的侵袭依赖于肌动蛋白-肌球蛋白的收缩性和金属蛋白酶的活性。 | Sumajit, H. | N/A | Glioblastoma invasion relies on actomyosin contractility and metalloproteinase activity | |
| 基于Hsp90-Tau相互作用的合成伴侣蛋白抑制病理性Tau聚集并恢复生理性Tau-微管相互作用 | Di Lorenzo, D. | N/A | Synthetic chaperone based on Hsp90-Tau interaction inhibits pathological Tau aggregation and rescues physiological Tau-Microtubule interaction | |
| PHD3-FOXO3轴调节小胶质细胞中的I型干扰素反应，加剧阿尔茨海默病进展 | Sanchez-Garcia, M. A. | N/A | The PHD3-FOXO3 axis modulates the interferon type I response in microglia aggravating Alzheimer's disease progression | |
| 雌性小鼠犁鼻器中雄性特征的表达及其在动情周期中的稳定性 | Ben-Shaul, Y. | N/A | Representation of male features in the female mouse Accessory Olfactory Bulb, and their stability during the estrus cycle | |
| 检测身体对组织过度生长的生殖激素制动器：micrin/SgII-70 | Hart, J. E. | N/A | Detecting the bodys reproductive hormonal brake against tissue overgrowth: micrin/SgII-70 | |
| 高血压Bph/2小鼠与正常血压Bpn/3小鼠之间淋巴细胞亚群的差异组成及激活状态 | Dattmore, D. A. | N/A | Differential composition of lymphocyte subpopulations and activation between the hypertensive Bph/2 and normotensive Bpn/3 mouse strains | |
| 荷斯坦奶牛生乳中细菌群落的组成与肺炎克雷伯菌临床乳腺炎感染的发生相关 | O'Brien, B. | N/A | The Composition of the Bacterial Community in Raw Milk from Holstein Dairy Cattle Correlated with the Occurrence of Klebsiella pneumoniae Clinical Mastitis Infections | |
| 环境基质和水分是决定在简化土壤模拟环境中表达的微生物表型的关键因素。 | Rodriguez-Ramos, J. A. | N/A | Environmental matrix and moisture are key determinants of microbial phenotypes expressed in a reduced complexity soil-analog | |
| 一项针对三个国家的肠道微生物组分析显示，与饮食相关的分类群关联因地理位置和菌株而异。 | Khatib, L. | N/A | A three-country analysis of the gut microbiome indicates taxon associations with diet vary by location and strain | |
| Sciphy：一种使用顺序遗传谱系追踪数据的贝叶斯系统发育框架。 | Seidel, S. | N/A | Sciphy: A Bayesian phylogenetic framework using sequential genetic lineage tracing data. | |
| 鸟类捕食评估的准确性：相机陷阱测试橡皮泥毛虫作为猎物模型的有效性 | SCHILLE, L. | N/A | Accuracy in bird predation assessment: Camera traps testing the efficacy of plasticine caterpillars as prey models | |
| 重建MAPK信号网络的深层系统发育：通过多层次协同进化扩展实现功能特化 | Huang, E. | N/A | Reconstructing the deep phylogeny of the MAPK signaling network: functional specialization via multi-tier coevolutionary expansion | |
| 念珠菌基因组数据库：注释与可视化更新 | Lew-Smith, J. | N/A | The Candida Genome Database: Annotation and Visualization Updates | |
| 人工照明影响捕食性臭虫Orius insidiosus（Say）对西方花蓟马Frankliniella occidentalis（Pergande）的捕食效果 | Canovas, M. L. | N/A | Artificial lighting affects the predation performance of the predatory bug Orius insidiosus (Say) against the Western flower thrips Frankliniella occidentalis (Pergande) | |
| 一项简单的措施能减少小鼠的食量并降低肥胖率 | Barrett, M. R. | N/A | A simple action reduces food intake and obesity in mice | |
| 使用HarmoDecon缓解空间分辨转录组学中细胞类型反卷积的多尺度偏差 | Wang, Z. | N/A | Mitigation of multi-scale biases in cell-type deconvolution for spatially resolved transcriptomics using HarmoDecon | |
| ProteusAI：一个开源且用户友好的平台，用于机器学习引导的蛋白质设计和工程 | Funk, J. | N/A | ProteusAI: An Open-Source and User-Friendly Platform for Machine Learning-Guided Protein Design and Engineering | |
| 规范游戏：重新思考精准肿瘤学中药物反应预测的评估 | Codice, F. | N/A | The Specification Game: Rethinking the Evaluation of DrugResponse Prediction for Precision Oncology | |
| scChat：基于大型语言模型的单细胞RNA测序分析上下文助手 | Lu, Y.-C. | N/A | scChat: A Large Language Model-Powered Co-Pilot for Contextualized Single-Cell RNA Sequencing Analysis | |
| 比较分析Endoxifen、他莫昔芬和氟维司群：一种生物信息学方法揭示乳腺癌的作用机制 | Remmel, H. L. | N/A | Comparative analysis of Endoxifen, Tamoxifen and Fulvestrant: A Bioinformatics Approach to Uncover Mechanisms of Action in Breast Cancer | |
| 使用5-氨基乙酰丙酸诱导的光敏化光动力疗法在获得性药物抗性的胰腺癌细胞中的疗效得到增强 | Liu, Y. | N/A | Efficacy of photodynamic therapy using 5-aminolevulinic acid-induced photosensitization is enhanced in pancreatic cancer cells with acquired drug resistance | |
| 调节性T细胞通过淋巴毒素信号与肿瘤和内皮细胞进行交流。 | Piao, W. | N/A | Regulatory T cells crosstalk with tumor and endothelium through lymphotoxin signaling | |
| Erbin通过与NHERF1和Ezrin相互作用，在HER2阳性乳腺癌中稳定膜ErbB2信号复合物。 | JEONG, J. | N/A | Erbin interacts with NHERF1 and Ezrin to stabilize a membrane ErbB2 signaling complex in HER2-positive breast cancer | |
| 在心脏和肌肉中实现强效且持久的基因调控，使用化学定义的siRNAs | Fakih, H. H. | N/A | Potent and durable gene modulation in heart and muscle with chemically defined siRNAs | |
| 与槐叶苹共培养的水稻植株改变了根系结构和发育阶段的时机 | Cannavo', S. | N/A | Co-cultivating rice plants with Azolla filiculoides modifies root architecture and timing of developmental stages | |
| 与满江红共培养对整株水稻代谢组的影响超出了传统无机氮肥的作用 | Consorti, E. | N/A | Co-cultivation with Azolla affects the metabolome of whole rice plant beyond canonical inorganic nitrogen fertilization | |
| 细胞可塑性多步骤完成过程模型 | Chen, C. M. | N/A | A multi-step completion process model of cell plasticity | |
| 揭示赤拟谷盗（Tribolium castaneum，Herbst, 1797）在小麦粉中的化学与行为生态学：面粉代谢成分的改变及化学信号在调节甲虫行为和调控种群增长中的作用。 | Das, S. | N/A | Unveiling the chemical and behavioural ecology of Tribolium castaneum (Herbst, 1797) in wheat flour: Alterations in flour metabolic content and the role of chemical cues in modulating beetles' behaviour and regulating population growth. | |
| 从斑马鱼中获得的稳定初级脑细胞培养物显示，scn1lab突变体中的非神经元细胞出现过度增殖。 | Odierna, L. | N/A | Stable primary brain cell cultures from zebrafish reveal hyperproliferation of non-neuronal cells from scn1lab mutants | |
| 细菌补充剂通过肠-脑轴减轻盆腔放疗引起的大脑代谢紊乱：一项多组学研究 | Venkidesh, B. S. | N/A | Bacterial Supplements Attenuate Pelvic Irradiation-Induced Brain Metabolic Disruptions via the Gut-Brain Axis: A Multi-Omics Investigation | |
| 功能失调的LHX6苍白球-丘脑底核投射在小鼠Leigh综合征模型中介导癫痫发作 | Sanchez-Benito, L. | N/A | Dysfunctional LHX6 pallido-subthalamic projections mediate epileptic events in a mouse model of Leigh Syndrome | |
| 设计实验方案以在受控实验室环境中引发警觉性变化 | Zahran, S. | N/A | Designing Experimental Protocols to Elicit Vigilance Variations in Controlled Laboratory Settings | |
| 在PrP.TDP43-315 ALS模型中，采用组合方法治疗ALS；并发症与困境 | Fromholt, S. | N/A | A combinatorial approach to ALS therapies in the PrP.TDP43-315 model of ALS; complications and tribulations | |
| 过滤点过程能够有效捕捉神经电生理记录中的节奏性和宽带功率谱结构 | Bloniasz, P. F. | N/A | Filtered Point Processes Tractably Capture Rhythmic And Broadband Power Spectral Structure in Neural Electrophysiological Recordings | |
| 脑干神经元协调膀胱和尿道括约肌以进行排尿 | Li, X. | N/A | Brainstem neurons coordinate the bladder and urethra sphincter for urination | |
| 病原体在微生物毒力和宿主抵抗力变化中的致病性 | Gupta, A. | N/A | Pathogenicity across variation in microbial virulence and host resistance | |
| 表达嵌合细胞因子受体的巨噬细胞在IL-10或TGFβ刺激下表现出炎症表型并具有抗肿瘤活性。 | Traxel, S. | N/A | Macrophages expressing chimeric cytokine receptors have an inflammatory phenotype and anti-tumoral activity upon IL-10 or TGFβ stimulation | |
| 通过多种丁酰胆碱酯酶激活Vγ9Vδ2 TCR的冷冻电镜结构洞察 | Zhang, M. | N/A | Cryo-EM structural insights into Vγ9Vδ2 TCR activation via multiple butyrophilins | |
| TYK2抑制增强了Treg的分化和功能，同时防止了Th1和Th17的分化。 | Tuomela, K. | N/A | TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differnetiation | |
| 第四代PDCD1驱动IL-10的CAR Tregs具有增强的抑制功能 | Boardman, D. A. | N/A | Fourth generation CAR Tregs with PDCD1-driven IL-10 have enhanced suppressive function | |
| 发育中的人类肺部空间解析蓝图揭示了一种由WNT驱动微环境调控的基底细胞群体 | Hsu, P. P. | N/A | A spatially-resolved blueprint of the developing human lung reveals a basal cell population regulated by a WNT-driven niche | |
| 在扁形动物的外上皮中，损伤诱导的转录对于组织再生至关重要。 | Barai, P. | N/A | Injury-induced transcription in the planarian outer epithelium is critical for tissue regeneration | |
| 实验室进化的高温适应性大肠杆菌菌株的基因组分析 | McGuire, B. E. | N/A | Genomic analysis of laboratory-evolved, heat-adapted Escherichia coli strains | |
| mRNA表达受非核仁RNA聚合酶I的共同调控。 | Carter, L. M. | N/A | mRNA expression is co-regulated by non-nucleolar RNA polymerase I | |
| 通过scDEEP-mC实现的高覆盖度、等位基因解析的单细胞DNA甲基化分析揭示了细胞谱系、X染色体失活状态及复制动力学 | Spix, N. J. | N/A | High-coverage allele-resolved single-cell DNA methylation profiling by scDEEP-mC reveals cell lineage, X-inactivation state, and replication dynamics | |
| 一种新型行为装置，用于在大鼠中进行自发探索和操作性条件下的社会信息空间条件化 | Wise, T. B. | N/A | A novel behavioral apparatus for spontaneous exploration and operant conditioning of social information under spatial conditions in rats | |
| 利用人工智能衍生平台确定针对主动脉瓣肌成纤维细胞激活的药物组合中的性别差异 | Vogt, B. J. | N/A | Determining sex differences in drug combinations targeting aortic valve myofibroblast activation using an artificial intelligence derived platform | |
| 一种低成本、开源的3D打印机，适用于多材料和高通量直接墨水书写软性和活体材料的打印。 | Weiss, J. D. | N/A | A low-cost, open-source 3D printer for multimaterial and high-throughput direct ink writing of soft and living materials | |
| 数字光处理3D打印技术实现了高效的人工心脏组织制造，用于疾病模型构建 | Dhand, A. P. | N/A | Digital Light Processing 3D Printing enables High Throughput Fabrication of Human Engineered Heart Tissues for Disease Modeling | |
| 工程化全肺用于组织生物学研究 | Greaney, A. M. | N/A | Engineered Whole Lungs for Tissue Biology | |
| 纳米级可生物降解打印技术用于设计调节疫苗递送动力学 | Peeler, D. J. | N/A | Nanoscale biodegradable printing for designed tuneability of vaccine delivery kinetics | |
| 针对蛋白酶降解的疫苗（PROTAVs）用于强效肿瘤联合免疫疗法 | Wang, Q. | N/A | Proteolysis-targeting vaccines (PROTAVs) for robust tumor combination immunotherapy | |
| BioLLMNet：通过专用跨LLM转换网络增强RNA相互作用预测 | Tahmid, M. T. | N/A | BioLLMNet: Enhancing RNA-Interaction Prediction with a Specialized Cross-LLM Transformation Network | |
| PertEval-scFM：基准测试单细胞基础模型用于扰动效应预测 | Wenteler, A. | N/A | PertEval-scFM: Benchmarking Single-Cell Foundation Models for Perturbation Effect Prediction | |
| scMODAL：一种通用的深度学习框架，用于具有特征链接的综合单细胞多组学数据对齐 | Wang, G. | N/A | scMODAL: A general deep learning framework for comprehensive single-cell multi-omics data alignment with feature links | |
| 临床和分子变异特性对变异效应预测工具的校准和性能的影响 | Isakov, O. | N/A | The Impact of Clinical and Molecular Variant Properties on Calibration and Performance of Variant Effect Prediction Tools | |
| 心室心律失常综合征相关KCNJ2突变的原子级研究 | Munawar, S. | N/A | Atomic-Level Investigation of KCNJ2 Mutations Associated with Ventricular Arrhythmic Syndrome Phenotypes | |
| 表型可塑性可以是对波动环境的一种进化反应。 | Garcia-Galindo, P. | N/A | Phenotypic plasticity can be an evolutionary response to fluctuating environments | |
| CYP3A5抑制导致G1/S阻滞，并与CDK4/6抑制剂协同抑制前列腺癌细胞生长：减少健康差异的意义 | Sharma, J. | N/A | CYP3A5 inhibition causes G1/S blockade and synergizes with CDK4/6 inhibitor to suppress prostate cancer cell growth: Implications in reducing health disparity | |
| 靶向FEN1以提高PARP抑制剂在三阴性乳腺癌中的疗效 | Frederick, M. I. | N/A | Targeting FEN1 to enhance efficacy of PARP inhibition in triple-negative breast cancer | |
| 线粒体活性氧在肥厚型心肌病中引起心律失常 | Kohlhaas, M. | N/A | Mitochondrial reactive oxygen species cause arrhythmias in hypertrophic cardiomyopathy | |
| 茄科中一个生物合成基因簇的亚功能化和表观遗传调控 | Priego-Cubero, S. | N/A | Sub-functionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae | |
| 脯氨酸-2'-脱氧麦根酸（PDMA）通过缓解石灰性碱性条件下大豆的缺铁症状，提高了种子质量和产量。 | Kaya, Z. | N/A | Proline-2'-deoxymugineic acid (PDMA) increases seed quality and yield by alleviating iron deficiency symptoms in soybean under calcareous-alkaline conditions | |
| 异源性烟碱乙酰胆碱受体通过在运动和感觉整合位点传递GABA能信号来促进睡眠。 | Yumita, T. | N/A | A heteromeric nicotinic acetylcholine receptor promotes sleep by relaying GABAergic signals within a locus of motor and sensory integration | |
| 通过抑制Notch信号通路实现感觉毛细胞的再生与前庭功能的恢复 | Lahlou, H. | N/A | Regeneration of Sensory Hair Cells and Restoration of Vestibular Function by Notch Inhibition | |
| 边缘光谱估计 | Patel, S. | N/A | Spectral estimation at the edge | |
| 性别在神经元对缺氧压力的反应中是否起作用？ | Voogd, E. J. H. F. | N/A | Does sex matter in neurons response to hypoxic stress? | |
| 生理和损伤诱导的微胶质细胞动态变化贯穿整个生命周期 | Tieu, T. | N/A | Physiological and injury-induced microglial dynamics across the lifespan | |
| 婴儿开放大脑：一个婴儿脑部分割的开源仓库 | Feczko, E. J. | N/A | Baby Open Brains: An Open-Source Repository of Infant Brain Segmentations | |
| 下午至傍晚的明亮光线暴露会减少青少年晚些时候的褪黑素分泌。 | Lazar, R. | N/A | Afternoon to early evening bright light exposure reduces later melatonin production in adolescents | |
| 短期热量限制或白藜芦醇补充剂改变了雄性和雌性大鼠的大规模脑网络连接 | van Rooij, J. R. A. | N/A | Short-term caloric restriction or resveratrol supplementation alters large-scale brain network connectivity in male and female rats | |
| 使用雾化模式识别受体激动剂的免疫疗法可恢复严重免疫麻痹，并改善流感相关性肺曲霉病小鼠的预后。 | Garcia, J. P. | N/A | Immunotherapy with nebulized pattern recognition receptor agonists restores severe immune paralysis and improves outcomes in mice with influenza-associated pulmonary aspergillosis | |
| 心肌炎和中性粒细胞介导的血管渗漏，而非细胞因子风暴，与致命的小鼠钩端螺旋体病相关。 | Papadopoulos, S. | N/A | Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosis | |
| 果蝇腹部组织大小变化时的生长补偿 | Ferreira, A. | N/A | Growth compensation upon changes in tissue size in the Drosophila abdomen | |
| 组织特异性转录组学揭示了专家幼鱼下颌差异背后的新颅面基因 | Palominos, M. F. | N/A | Tissue-specific transcriptomics uncovers novel craniofacial genes underlying jaw divergence in specialist pupfishes | |
| 红砂岩表面微生物群落：尽管在分散限制和异质选择下分类学上存在差异，但功能趋同 | Wang, B. | N/A | Red sandstone surface microbiota: functional convergence despite taxonomic divergence under dispersal limitation and hetero selection | |
| 热带北太平洋四种新型绿藻病毒的基因组多样性和全球分布 | Bedi de Silva, A. | N/A | Genomic diversity and global distribution of four new prasinoviruses from the tropical North Pacific | |
| 硬蜱幼虫更喜欢含有伯氏疏螺旋体感染且皮质类固醇浓度较低的血液。 | Vanroy, T. | N/A | Ixodes ricinus nymphs prefer blood with Borrelia infection and low corticosteroid concentration | |
| 放射虫的多样性与演化：超越海洋之星 | Mendez Sandin, M. | N/A | Diversity and evolution of Radiolaria: Beyond the stars of the ocean | |
| 蛋白质-蛋白质相互作用塑造了遗传变异对蛋白质表达和复杂性状的反式调控影响 | Li, J. | N/A | Protein-protein interactions shape trans-regulatory impact of genetic variation on protein expression and complex traits | |
| 一个关于秀丽隐杆线虫RNAi遗传的遗传框架 | Ketting, R. F. | N/A | A genetic framework for RNAi inheritance in Caenorhabditis elegans | |
| 铂金血统：一种用于基因变异的长读基准 | Kronenberg, Z. | N/A | The Platinum Pedigree: A long-read benchmark for genetic variants | |
| 人乳头瘤病毒（HPV）相关宫颈上皮内瘤变组织的空间分析显示，与宫颈癌进展相关的独特免疫特征。 | Pavilion, G. L. | N/A | Spatial analysis of HPV associated cervical intraepithelial neoplastic tissues demonstrate distinct immune signatures associated with cervical cancer progression | |
| 蝴蝶大脑在短暂接触信息素后，其形态和基因剪接模式会发生改变。 | Dion, E. | N/A | Butterfly brains change in morphology and in gene splicing patterns after brief pheromone exposure | |
| 雄性和雌性小鼠在社会压力诱导的动机方面存在差异性变化 | McGraw, M. | N/A | Divergent changes in social stress-induced motivation in male and female mice | |
| 海盗：掠夺AlphaFold预测以自动化蛋白质工程 | Richardson, G. | N/A | PIRATE: Plundering AlphaFold Predictions to Automate Protein Engineering | |
| OpenExo：一款开源模块化外骨骼，用于增强人体功能 | Williams, J. R. | N/A | OpenExo: An Open-Source Modular Exoskeleton to Augment Human Function | |
| 通过斜向光热显微镜实现的超灵敏活体红外光谱成像 | Li, M. | N/A | Ultrasensitive in vivo infrared spectroscopic imaging via oblique photothermal microscopy | |
| 高通量形态筛选鉴定出化学定义的间充质基质细胞培养基，可增强细胞增殖并支持免疫调节功能的维持。 | Spoerer, T. M. | N/A | High Throughput Morphological Screening Identifies Chemically Defined Media for Mesenchymal Stromal Cells that Enhances Proliferation and Supports Maintenance of Immunomodulatory Function | |
| 神经群体方差解释了学习过程中适应性差异 | Stealey, H. M. | N/A | Neural population variance explains adaptation differences during learning | |
| 微孔板微加工：一种可定制的平台，支持微生理培养模型的原型设计、开发和测试 | Reynolds, J. I. | N/A | Microplate micromilling: A customizable platform to support the prototyping, development and testing of microphysiological culture models | |
| 一项针对具有形态多样解剖结构的人类主动脉CT图像的U-Net三维图像分割研究 | Chen, J. | N/A | A 3D Image Segmentation Study of U-Net on CT Images of the Human Aorta with Morphologically Diverse Anatomy | |
| 使用多模态神经网络在多频率谐波运动和B模式成像上进行自动肿瘤和FUS病灶量化 | Hu, S. | N/A | Automated Tumor and FUS Lesion Quantification on Multi-frequency Harmonic Motion and B-mode Imaging Using a Multi-modality Neural Network | |
| 一种新的压缩策略，用于减小纳米孔测序数据的大小 | Jayasooriya, K. | N/A | A new compression strategy to reduce the size of nanopore sequencing data | |
| EvoSeq-ML：借助进化信息引导的蛋白质序列表示与生成推进数据中心机器学习 | Mardikoraem, M. | N/A | EvoSeq-ML: Advancing Data-Centric Machine Learning with Evolutionary-Informed Protein Sequence Representation and Generation | |
| 利用Spacedust在微生物基因组中发现保守基因簇的新方法 | Zhang, R. | N/A | De novo discovery of conserved gene clusters in microbial genomes with Spacedust | |
| 用于冷冻电镜中鲁棒目标检测的新统计度量——2DTM | Zhang, K. | N/A | New Statistical Metric for Robust Target Detection in Cryo-EM Using 2DTM | |
| 两栖动物saxiphilins结合和中和石房蛤毒素同系物的结构基础 | Zakrzewska, S. | N/A | Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins | |
| 盐酸胍对胸腺α1和α-突触核蛋白形状的影响截然不同 | Liu, Z. | N/A | Impact of Guanidine Hydrochloride on the shapes of Prothymosin-α and α-Synuclein is dramatically different | |
| 照亮根系-土壤力学 | Le Houx, J. | N/A | Illuminating root-soil mechanics | |
| 使适配体更具抗体样特性：利用瓶刷聚合物偶联的适配体在体内靶向AXL | Sun, T. | N/A | Making Aptamers More Antibody-like: Targeting AXL in Vivo Using a Bottlebrush Polymer-Conjugated Aptamer | |
| BoMBR：一个用于网状纤维分割的骨髓活检数据集 | Raina, P. | N/A | BoMBR: An Annotated Bone Marrow Biopsy Dataset for Segmentation of Reticulin Fibers | |
| 黄瓜花叶病毒的sRNA调节症状影响桃蚜的取向和取食行为 | Wrzesinska-Krupa, B. | N/A | Symptom-modulating satRNAs of cucumoviruses affect the orientation and feeding behaviour of Myzus persicae | |
| 癌胚蛋白Nogo-A通过VEGF-Notch-Hippo-代谢信号通路限制人源和鼠源胶质瘤的血管化和生长 | Schwab, M. | N/A | Onco-fetal protein Nogo-A restricts human and mouse glioma vascularization and growth via VEGF-Notch-hippo-metabolic signaling | |
| 运动想象提高老年和年轻女性的力量控制能力 | Calkins, C. A. | N/A | Motor Imagery Improves Force Control in Older and Young Females | |
| 大鼠下丘脑和未定带（Zona Incerta）的化学构筑研究。Chemopleth 1.0，一个可下载的交互式脑图空间数据库，包含五个可同时可视化的神经化学系统，并配备了新颖的特征和基于网格的映射工具。 | Navarro, V. I. | N/A | Chemoarchitectural studies of the rat hypothalamus and zona incerta.Chemopleth 1.0, a downloadable interactive Brain Maps spatial database of five co-visualizable neurochemical systems, with novel feature- and grid-based mapping tools | |
| 通过无偏细胞类型分布聚类揭示的大脑结构组织 | Munoz-Castaneda, R. | N/A | Brain Structural Organization Revealed by Unbiased Cell-Type Distribution Clustering | |
| 通过交叉验证多尺度多模态数据，重建小鼠大脑中单个神经元的连接组 | Xiong, F. | N/A | Reconstruct a Connectome of Single Neurons in Mouse Brains by Cross-Validating Multi-Scale Multi-Modality Data | |
| 药物增强慢波活动可改善认知功能并减少阿尔茨海默病小鼠模型早期阶段的淀粉样病变。 | Kollarik, S. | N/A | Pharmacological enhancement of slow-wave activity improves cognition and reduces amyloidosis at an early stage in a mouse model of Alzheimer's disease | |
| 自上而下的反馈很重要：类脑连接模式对视听整合的功能影响 | Tugsbayar, M. | N/A | Top-down feedback matters: Functional impact of brainlike connectivity motifs on audiovisual integration | |
| 多实验室研究确立了在人工生态系统中进行植物微生物组研究的可靠方法 | Novak, V. | N/A | Multi-laboratory Study Establishes Reproducible Methods for Plant-Microbiome Research in Fabricated Ecosystems | |
| 微小RNA和RNA结合蛋白介导的转录后调控对于早期胚胎细胞命运的决定至关重要。 | Sangokoya, C. | N/A | Coordinate post-transcriptional regulation by microRNAs and RNA binding proteins is critical for early embryonic cell fate decisions | |
| 季节性接触和迁徙结构影响宽吻海豚的群体性流行病，并为疫情准备提供信息。 | Collier, M. A. | N/A | Seasonal contact and migration structure mass epidemics and inform outbreak preparedness in bottlenose dolphins | |
| 干旱啮齿动物在转录组和基因组层面的趋同适应 | Chalopin, D. | N/A | Convergent transcriptomic and genomic adaptation in xeric rodents | |
| 解开水损失与呼吸之间普遍权衡关系的塑料机制 | Assis, B. A. | N/A | Plastic mechanisms for unraveling a universal trade-off between water loss and respiration | |
| G4mer：一种RNA语言模型，用于从群体规模的遗传数据中识别转录组范围内的G-四链体和疾病变异 | Zhuang, F. | N/A | G4mer: An RNA language model for transcriptome-wide identification of G-quadruplexes and disease variants from population-scale genetic data | |
| 秀丽隐杆线虫的LON-1蛋白需要其CAP结构域来实现调节身体大小和BMP信号传导的功能。 | Serrano, M. V. | N/A | The C. elegans LON-1 protein requires its CAP domain for function in regulating body size and BMP signaling | |
| 系统性实证评估个体碱基编辑靶点：验证USH2A中的治疗靶点及方法比较 | Tachida, Y. | N/A | Systematic empirical evaluation of individual base editing targets: validating therapeutic targets in USH2A and comparison of methods | |
| 染色质模型比较与验证的挑战：来自第一届国际4D Nucleome黑客马拉松的项目 | Kubica, J. | N/A | The challenge of chromatin model comparison and validation a project from the first international 4D Nucleome Hackathon | |
| 宿主基因组驱动虾微生物群的多样性、丰富性和有益微生物：一种全基因组视角。 | Cornejo-Granados, F. | N/A | Host Genome Drives the Diversity, Richness, and Beneficial Microbes in the Shrimp Microbiota: A Hologenome Perspective. | |
| 人类血液白细胞成分在呼吸道病毒接种后反应的时间高分辨率图谱 | Zhang, Y. | N/A | Temporal High-Resolution Atlas of Human Blood Leukocyte Composition in Response to Respiratory Virus Inoculation | |
| 多细胞生物中单细胞增强子活性的空间重建 | Alberti, B. | N/A | Spatial reconstruction of single-cell enhancer activity in a multicellular organism | |
| 结合纳米液滴成像与超声定位显微技术用于检测脑内出血 | LIN, B.-Z. | N/A | Combined Nanodrops Imaging and Ultrasound Localization Microscopy for Detecting Intracerebral Hemorrhage | |
| 支链氨基酸（BCAA）组装成有毒纤维丝可能与枫糖尿症（MSUD）的发病机制有关。 | Kanth, C. P. | N/A | Assembly of branched chain amino acid (BCAA) to toxic fibrils may be related to pathogenesis of Maple syrup urine disease (MSUD) | |
| 基于级联向量化的化合物-蛋白质相互作用预测模型 | Williams, G. | N/A | A Predictive Model for Compound-Protein Interactions Based on Concatenated Vectorization | |
| 消除病毒知识以实现安全且负责任地预测变异效果 | Li, M. | N/A | Unlearning Virus Knowledge Toward Safe and Responsible Mutation Effect Predictions | |
| CellEKT：一种稳健的化学蛋白质组学工作流程，用于分析激酶抑制剂的细胞靶点参与情况 | Ruegger, J. | N/A | CellEKT: A robust chemical proteomics workflow to profile cellular target engagement of kinase inhibitors | |
| 微小标签（Microbetag）：通过注释、富集测试和代谢互补分析简化微生物网络解释 | Zafeiropoulos, H. | N/A | microbetag: simplifying microbial network interpretation through annotation, enrichment tests and metabolic complementarity analysis | |
| 从随机动力学和时空模式中学习机器学习稀疏反应扩散模型 | Abubaker-Sharif, B. | N/A | Machine learning sparse reaction-diffusion models from stochastic dynamics and spatiotemporal patterns | |
| 遮荫对美国佛罗里达群岛加勒比海八放珊瑚Briareum asbestinum行为生态的影响 | Draud, S. L. | N/A | Influence of Shading on the Behavioral Ecology of a Caribbean Alcyonacean Octocoral, Briareum asbestinum, in the Florida Keys, United States | |
| 利用碱性磷酸酶（AP）免疫标记方法研究fms样酪氨酸激酶3（FLT3）及其他神经元蛋白的细胞及亚细胞分布特征 | Yin, Y. | N/A | Characterization of the cellular and subcellular distribution of fms-like tyrosine kinase 3 (FLT3) and other neuronal proteins using an alkaline phosphatase (AP) immunolabeling method | |
| 血清素增强神经发生生物标志物、海马体积和阿尔茨海默病中的认知功能 | Azargoonjahromi, A. | N/A | Serotonin Enhances Neurogenesis Biomarkers, Hippocampal Volumes, and Cognitive Functions in Alzheimer's Disease | |
| 跨任务含义：海马事件边界反应如何预测无关的记忆表现 | van Dijk, D. | N/A | Cross-task implications: How hippocampal event boundary responses predict unrelated memory performance | |
| 利用高扩散加权强度增强的结构脑连接分析 | Yu, L. | N/A | Enhanced Structural Brain Connectivity Analyses Using High Diffusion-weighting Strengths | |
| 刺激历史，而非预期，驱动了哺乳动物大脑皮层中的感觉预测误差。 | Westerberg, J. A. | N/A | Stimulus history, not expectation, drives sensory prediction errors in mammalian cortex | |
| Tbc1d15 在体内的敲低通过促进自噬减轻了 α-突触核蛋白诱导的神经毒性。 | Siddiqi, F. H. | N/A | Tbc1d15 knockdown in vivo alleviates α-synuclein-induced neurotoxicity by promoting autophagy. | |
| 推进适应性细胞疗法：优化适应性自然杀伤细胞在实体瘤中的扩增 | Almazan, N. M. | N/A | Advancing Adoptive Cell Therapy: Optimized Expansion of Adaptive NK Cells for Solid Tumors | |
| 在抗逆转录病毒治疗的人类免疫缺陷病毒（HIV）感染者中，结肠CD8+ T细胞中PPARγ的下调导致上皮屏障破坏。 | Das Adhikari, U. | N/A | PPARγ downregulation in colonic CD8+ T cells results in epithelial barrier disruption in people with HIV on antiretroviral therapy | |
| IL-1β信号在人类淋巴组织中调节T滤泡辅助细胞和调节性T细胞 | Vaineau, R. | N/A | IL-1β Signaling Modulates T Follicular Helper and Regulatory Cells in Human Lymphoid Tissues | |
| 通过宏基因组学洞察伊利湖中金属和抗生素抗性基因的时空变化 | Reddy, S. | N/A | Metagenomic Insights into the Spatio-temporal Variation of Metal and Antibiotic Resistance Genes in Lake Erie | |
| 首个多用途的猫冠状病毒反向遗传系统 | Kida, I. | N/A | First versatile reverse genetics system for feline coronavirus | |
| skalo：使用SKA分割k-mers与着色de Brujin图进行插入缺失基因分型 | Derelle, R. | N/A | skalo: using SKA split k-mers with coloured de Brujin graphs to genotype indels | |
| 甘油提高了冷冻保存领鞭虫的存活率。 | Chandra, S. | N/A | Glycerol improves the viability of a cryopreserved choanoflagellate | |
| 基于栖息地面积和状况的指标并不能很好地反映无脊椎动物的生物多样性。 | Duffus, N. E. | N/A | Metrics based on habitat area and condition are poor proxies for invertebrate biodiversity | |
| 两种热带果蝇同时入侵沙漠环境中的差异与趋同性 | Elsabrout, A. | N/A | Divergence and parallelism in two tropical drosophilids simultaneously invading a desert environment | |
| 雌性异配甲基组中的剂量补偿与性冲突 | Tangili, M. | N/A | Dosage compensation and sexual conflict in female heterogametic methylomes | |
| 了解普通秋沙鸭的遗传多样性和系统地理学，及其在克什米尔喜马拉雅湿地中与其他水鸟物种的系统发育关系。 | Ahmad, K. | N/A | Understanding genetic diversity and phylogeography of Common Teal and its phylogenetic relationship with other water bird species in the wetlands of Kashmir Himalayas. | |
| 爱德华兹珊瑚爱德华西亚·埃莱根斯的新基因组 | Rutlekowski, A. | N/A | De-novo Genome of the Edwardsiid anthozoan Edwardsia elegans | |
| 解码胶原蛋白的热诱导展开和重折叠途径 | Al-Shaer, A. | N/A | Decoding Collagen's Thermally Induced Unfolding and Refolding Pathways | |
| Cdv蛋白之间的相互作用层次结构驱动其招募至膜颈区域 | De Franceschi, N. | N/A | Interaction hierarchy among Cdv proteins drives recruitment to membrane necks | |
| 整合可持续有机纳米酶与现场传感平台，实现农业与生物分子双重检测 | Lee, D. H. | N/A | Consolidated sustainable organic nanozyme integrated with Point-Of-Use sensing platform for dual agricultural and biological molecule detection | |
| ChIPbinner：一个用于分析ChIP-Seq或CUT&RUN/TAG数据中在均匀窗口内分箱的广义组蛋白标记的R包 | Padilla, R. | N/A | ChIPbinner: An R package for analyzing broad histone marks binned in uniform windows from ChIP-Seq or CUT&RUN/TAG data | |
| 空间多组学的马赛克整合与SpaMosaic | Yan, X. | N/A | Mosaic integration of spatial multi-omics with SpaMosaic | |
| 全双曲神经网络：一种研究衰老轨迹的新方法 | Ramirez, H. | N/A | Fully Hyperbolic Neural Networks: A Novel Approach to Studying Aging Trajectories | |
| 创建：通过离散嵌入识别细胞类型特异的顺式调控元件 | Cui, X. | N/A | CREATE: cell-type-specific cis-regulatory elements identification via discrete embedding | |
| Gas1介导的肝母细胞瘤肿瘤发生抑制 | Chen, K. | N/A | Gas1-Mediated Suppression of Hepatoblastoma Tumorigenesis | |
| BaMBo：一个用于分割任务的带注释骨髓活检数据集 | Singh, A. | N/A | BaMBo: An Annotated Bone Marrow Biopsy Dataset for Segmentation Task | |
| GRIN2B疾病相关突变破坏了BK通道和NMDA受体信号纳米域的功能 | Martinez-Lazaro, R. | N/A | GRIN2B disease-associated mutations disrupt the function of BK channels and NMDA receptor signalling nanodomains | |
| 埃塞俄比亚中南部地区小麦叶枯病菌群体的遗传多样性 | Tucho, A. | N/A | Genetic Diversity of Zymoseptoria tritici Populations in Central and South-eastern Ethiopia | |
| 可调节低速率的基因组重组与大肠杆菌中的Cre-lox系统：合成生物学和环境感知的通用工具 | Garabello, E. | N/A | Tunable Low-Rate Genomic Recombination with Cre-lox in E. coli: A Versatile Tool for Synthetic Biology and Environmental Sensing | |
| 少突胶质细胞利用突触后蛋白来协调在不同神经递质类别的轴突上形成髓鞘。 | Carey, N. | N/A | Oligodendrocytes use post-synaptic proteins to coordinate myelin formation on axons of distinct neurotransmitter classes | |
| Fms样激酶3（FLT3）的药理学抑制促进了神经元的成熟并在小鼠模型中抑制了癫痫发作。 | Cruite, K. | N/A | Pharmacological inhibition of Fms-like kinase 3 (FLT3) promotes neuronal maturation and suppresses seizure in a mouse model | |
| 脉冲神经网络的最优控制 | Costa, T. | N/A | Optimal control of spiking neural networks | |
| 一种靶向膜的光开关在退化的视网膜中恢复了对光的生理开/关响应 | Benfenati, F. | N/A | A membrane-targeted photoswitch restores physiological ON/OFF responses to light in the degenerate retina | |
| Pannexin-2 缺陷的斑马鱼表现出眼部和视觉运动行为缺陷。 | Shanbhag, R. | N/A | Pannexin-2 deficient zebrafish develop ocular and visual motor behaviour defects | |
| 一种用于相关分析的热塑性芯片，结合了免疫细胞反应的筛选与高分辨率成像 | van Ooijen, H. | N/A | A thermoplastic chip for correlative assays combining screening and high-resolution imaging of immune cell responses | |
| 初始CD4+ T细胞库的异质性与可塑性 | Sajani, A. | N/A | Heterogeneity and plasticity of the naive CD4+ T cell compartment | |
| 智利高盐湖中的后生动物多样性通过环境DNA被揭示 | Sacco, M. | N/A | Metazoan diversity in Chilean hypersaline lakes unveiled by environmental DNA | |
| EDTA试管适用于在资源有限的环境中进行胰岛素和C肽的检测，并且可以在室温下保存长达24小时。 | Nathan, M. | N/A | EDTA tubes are suitable for insulin and C-peptide measurement in resource-limited settings and can be stored at room temperature for up to 24 hours | |
| 衣藻中淀粉颗粒的形成不需要淀粉合酶4同工型。 | COURSEAUX, A. | N/A | Starch granule initiation doesnt require a starch synthase 4 isoform in Chlamydomonas reinhardtii. | |
| 推进无创机械通气：模拟技术提升呼吸护理效果 | Tahmid, M. T. | N/A | Advancing Noninvasive Mechanical Ventilation:Simulating Techniques for Improved Respiratory Care | |
| 情感调节障碍儿童的奖励加工 | Aggensteiner, P. M. | N/A | Reward processing in children with Affective Dysregulation | |
| Theta-gamma经颅交流电刺激增强健康年轻和老年人的运动技能习得 | Gamage, N. N. | N/A | Theta-gamma transcranial alternating current stimulation enhances motor skill acquisition in healthy young and older adults | |
| 中间神经元特化的命运可塑性 | Mostajo-Radji, M. A. | N/A | Fate plasticity of interneuron specification | |
| 性别化的肠道和口腔微生物群变化：揭示胰腺癌中的性别特异性菌群失调 | Khan, Z. A. | N/A | Genderized Gut and Oral Microbiome Shifts: Uncovering Sex-Specific Dysbiosis in Pancreatic Cancer | |
| 免疫肽组学助力结核分枝杆菌MHC-II抗原的发现与疫苗设计中的应用 | Leddy, O. | N/A | Immunopeptidomics informs discovery and delivery of Mycobacterium tuberculosis MHC-II antigens for vaccine design | |
| 肠道微生物对原发性硬化性胆管炎-炎症性肠病模型中结肠炎及结肠炎相关癌变的影响 | Awoniyi, M. | N/A | Gut Microbial Impact on Colitis and Colitis-Associated Carcinogenesis in a Primary Sclerosing Cholangitis-IBD Model | |
| 构建一个社区驱动的生物信息学平台，以促进大麻（Cannabis sativa）多组学研究 | Mansueto, L. | N/A | Building a community-driven bioinformatics platform to facilitate Cannabis sativa multi-omics research | |
| 一种改进的TEAD显性负性蛋白抑制剂，用于研究Hippo YAP1/TAZ依赖性转录。 | Branch, B. | N/A | An improved TEAD dominant-negative protein inhibitor to study Hippo YAP1/TAZ-dependent transcription. | |
| CellStudio：一种模块化、可调节且易获取的平台，用于分析细胞培养中生长因子的分泌 | Azuaje-Hualde, E. | N/A | CellStudio: a Modular, Tunable and Accessible Platform for Analysis of Growth Factors Secretions in Cell Cultures | |
| 蜂鸟上喙弯曲作为适应花蜜采食的进化特征 | Rico-Guevara, A. | N/A | Upper bill bending as an adaptation for nectar feeding in hummingbirds | |
| STAMP：通过成像进行单细胞转录组分析和多模态表征 | Pitino, E. | N/A | STAMP: Single-Cell Transcriptomics Analysis and Multimodal Profiling through Imaging | |
| 一个针对环境16S rRNA牛津纳米孔测序数据分析的优化参考数据库 | Philip, M. | N/A | A Targeted Reference Database for Improved Analysis of Environmental 16S rRNA Oxford Nanopore Sequencing Data | |
| 实时时空追踪传染病在封闭环境中的爆发情况，采用宿主-病原体基于代理的系统 | Srinivasan, S. | N/A | Real-Time Spatiotemporal Tracking of Infectious Outbreaks in Confined Environments with a Host-Pathogen Agent-Based System | |
| 模拟溶质回火2 | Stratmann, D. | N/A | Simulated Solute Tempering 2 | |
| 血液生化改变及由北西埃塞俄比亚贡达ELFORA屠宰场宰杀绵羊的捻转血矛线虫病引起的病变特征 | Malede, B. A. | N/A | Haematobiochemical Alterations and Lesion Characterization Induced by Haemonchosis in Sheep Slaughtered at Gondar ELFORA Abattoir, North West Ethiopia | |
| 在人类、动物和婴儿配方奶粉中检测钛纳米颗粒 | Rivard, C. | N/A | Detection of titanium nanoparticles in human, animal and infant formula milk | |
| 饮食中的脂质主要沉积在皮肤中，并迅速影响其隔热性能。 | Riley, N. | N/A | Dietary lipid is largely deposited in skin and rapidly affects insulating properties | |
| 揭示间充质干细胞外泌体中的miRNAs在慢性酒精摄入引起的神经炎症和行为障碍中的作用 | Mellado, S. | N/A | Unveiling the role of miRNAs from MSC-EVs in neuroinflammation and behavioral impairments induced by chronic alcohol consumption | |
| 深度学习和分析模型在健康和精神分裂症的大脑结构-功能关系上给出了不同的结果。 | Cai, Q. | N/A | Deep-learning and analytical models give distinct results for the brain structure-function relationship in health and in psychosis | |
| HBN-EEG：健康大脑网络（HBN）脑电图数据集的FAIR实现 | Shirazi, S. Y. | N/A | HBN-EEG: The FAIR implementation of the Healthy Brain Network (HBN) electroencephalography dataset | |
| 探索脑机接口中深度学习与可解释模型之间的权衡 | Cubillos, L. H. | N/A | Exploring the trade-off between deep-learning and explainable models for brain-machine interfaces | |
| 内质网相关受体SorCS1-3的胞内结构域中存在一个三丝氨酸基序，该基序调控神经营养活性。 | Dalby, A. | N/A | A triple serine motif in the intracellular domains of sortilin-related receptors SorCS1-3 regulates neurotrophic activity | |
| 通过混合前额叶皮层资源实现动态注意力控制 | Di Bello, F. | N/A | Dynamic Attentional Control Through Mixed Prefrontal Cortex Resources | |
| 血清蛋白质组学揭示了通过追踪SARS-CoV2混合免疫对关注变异的高亲和力和趋同抗体 | Patel, A. | N/A | Serum proteomics reveals high-affinity and convergent antibodies by tracking SARS-CoV2 hybrid immunity to emerging variants of concern | |
| 加纳大塔马利都市区牛、牛肉及人类中沙门氏菌肠炎的基因组分析 | Sunmonu, G. T. | N/A | Genomic Analysis of Salmonella enterica from cattle, beef and humans in the Greater Tamale Metropolis of Ghana | |
| 人类星状病毒感染的新型小鼠模型揭示了其对心血管系统的趋向性 | Owen, M. C. | N/A | Novel murine model of human astrovirus infection reveals a cardiovascular tropism | |
| 微重力和低量缪子辐射影响秀丽隐杆线虫中的病毒致病性和生理学 | Villena-Gimenez, A. | N/A | Microgravity and low muon radiation affect viral pathogenesis and physiology in Caenorhabditis elegans | |
| 检测自北方短尾鼩（Blarina brevicauda）的新型副亨尼帕病毒 | Imai, S. | N/A | Detection of a novel parahenipavirus from northern short-tailed shrews (Blarina brevicauda ) | |
| 延迟的病毒清除和改变的炎症反应导致老年小鼠SARS-CoV-2感染的严重性增加。 | Lacasse, E. | N/A | Delayed viral clearance and altered inflammatory responses resulted in increased severity of SARS-CoV-2 infection in aged mice. | |
| 一种具有分离活性的双功能snoRNA，能够指导rRNA的2'-O-甲基化并作为配子发生效应器的支架 | Leroy, E. | N/A | A bifunctional snoRNA with separable activities in guiding rRNA 2'-O-methylation and scaffolding gametogenesis effectors | |
| 脂肪酸去饱和作用指导细胞在铁死亡和细胞衰老之间的决策 | Kuehnemann, C. | N/A | Fatty acid desaturation guides cellular decisions between ferroptosis and cellular senescence | |
| 衰老肌肉中肌原纤维大小、形状和网络连接的变化 | Ajayi, P. T. | N/A | Changes in Myofibril Size, Shape, and Network Connectivity in Aging Muscle | |
| 在再生过程中，VEGF信号在非血管组织的扩展中发挥着进化上保守的作用。 | Savage, A. M. | N/A | An evolutionarily conserved role for VEGF signaling in the expansion of non-vascular tissue during regeneration. | |
| 使用光谱流式细胞术对全细胞中核组蛋白H3的翻译后修饰进行分析 | Golden, C. S. | N/A | Nuclear Histone H3 Post-translational Modification Profiling in Whole Cells using Spectral Flow Cytometry | |
| 大豆锈病菌（Phakopsora pachyrhizi）的遗传多样性主要由两个主要的进化谱系所驱动。 | Rocha, V. D. d. | N/A | The genetic diversity of the soybean rust pathogen Phakopsora pachyrhizi has been driven by two major evolutionary lineages | |
| 基因与环境相互作用及美洲小鼠适应性体型变异 | Mack, K. L. | N/A | Gene-by-environment interactions and adaptive body size variation in mice from the Americas | |
| 蚂蚁嗅觉系统的祖先复杂性和受限多样化 | Marty, S. | N/A | Ancestral complexity and constrained diversification of the ant olfactory system | |
| 辐鳍鱼类非视觉和视觉视蛋白基因谱系的演化 | Policarpo, M. | N/A | Evolution of the non-visual and visual opsin gene repertoire in ray-finned fishes | |
| 性选择在遗传拯救中起着重要作用，但生产力的益处会随着时间而减弱；一项多代实验为保护工作提供信息。 | West, G. | N/A | Sexual selection matters in genetic rescue, but productivity benefits fade over time; a multi-generation experiment to inform conservation. | |
| 性别和遗传背景影响混合大鼠多样性面板中的静脉注射羟考酮自我给药 | Duffy, E. P. | N/A | Sex and genetic background influence intravenous oxycodone self-administration in the Hybrid Rat Diversity Panel | |
| 锥虫线粒体基因组分离复合体永久性外-内膜接触位点的分子特征 | Stettler, P. | N/A | Molecular characterization of the permanent outer-inner membrane contact site of the mitochondrial genome segregation complex in trypanosomes | |
| MDA5变异体对自身免疫性疾病保护作用的分子基础 | Singh, R. | N/A | Molecular basis of autoimmune disease protection by MDA5 variants | |
| 使用小分子方法对RNA鸟嘌呤-7甲基转移酶（RNMT）进行表征 | Pearson, L.-A. | N/A | Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach | |
| 具有序列控制骨架的瓶刷聚合物，用于增强寡核苷酸递送 | Wei, Y. | N/A | Bottlebrush polymers with sequence-controlled backbones for enhanced oligonucleotide delivery | |
| PoreMeth2：利用纳米孔测序解码甲基化组变化的演化 | Mattei, G. | N/A | PoreMeth2: decoding the evolution of methylome alterations with Nanopore sequencing | |
| HLAIIPred：用于建模HLA II类分子与肽段相互作用的交叉注意力机制 | Haghighatlari, M. | N/A | HLAIIPred: Cross-Attention Mechanism for Modeling the Interaction of HLA Class II Molecules with Peptides | |
| PUNCH2：探索内在无序蛋白质预测器的策略 | Meng, D. | N/A | PUNCH2: explore the strategy for Intrinsically Disordered Protein predictor | |
| Tannin1（高粱中拟南芥主调控因子TTG1的直系同源基因）的多效性调控功能丧失 | Schuh, A. | N/A | Loss of pleiotropic regulatory functions in Tannin1, the sorghum ortholog of Arabidopsis master regulator TTG1 | |
| 估算英格兰西南部野生鹿群中结核病（牛分枝杆菌）感染的抗体流行率 | Jinks, R. | N/A | Estimating the seroprevalence of tuberculosis (Mycobacterium bovis) infection in a wild deer population in southwest England | |
| 摆脱单个神经元的束缚：神经元在神经元集合中的选择性发生变化，其重构是动态编码的基础。 | Londei, F. | N/A | Out of the single-neuron straitjacket: neurons within assemblies change selectivity and their reconfiguration underlies dynamic coding | |
| 在转基因小鼠模型中限制听力损失 | Babola, T. A. | N/A | Limiting hearing loss in transgenic mouse models | |
| 升高的NAD+通过Sir2A介导的GCβ去乙酰化和OES定位，促进疟原虫卵形体的滑行运动和蚊媒感染 | Shi, Y. | N/A | Elevated NAD+ drives Sir2A-mediated GCβ deacetylation and OES localization for Plasmodium ookinete gliding and mosquito infection | |
| 肺上皮细胞稳态和免疫失调加剧了中东呼吸综合征冠状病毒疾病的严重性 | Sheahan, T. P. | N/A | Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East Respiratory Syndrome coronavirus disease severity | |
| 外显子转录组rRNA指纹分析揭示了组织来源和肿瘤特异性特征 | Milenkovic, I. | N/A | Epitranscriptomic rRNA fingerprinting reveals tissue-of-origin and tumor-specific signatures | |
| UBR4调控依赖于MetAP2的精氨酸/N-降解途径 | Morrison, E. J. | N/A | UBR4 regulates a MetAP2-dependent Arg/N-degron pathway | |
| TECPR2是一种Rab5效应器，调控内吞体货物再循环。 | Paul, S. | N/A | TECPR2 is a Rab5 effector that regulates endosomal cargo recycling | |
| 脂滴靶向ABHD5和PNPLA3 I148M是促进肝脏脂肪变性所必需的 | Teskey, G. | N/A | Lipid Droplet Targeting of ABHD5 and PNPLA3 I148M is required to promote liver steatosis | |
| 同时测量总氧进化和基础光合作用氧化还原反应：以蓝细菌为例的研究 | Liran, O. | N/A | Simultaneous Measurement of Gross Oxygen Evolution and Underlying Photosynthetic Redox Reactions: A Case Study Using Cyanobacteria | |
| DYRK1A激酶三倍体是唐氏综合征中中耳炎的主要病因。 | Tateossian, H. | N/A | DYRK1A kinase triplication is the major cause of Otitis Media in Down Syndrome | |
| 具有改变的RNA结合和降解活性的病理性PNPase变体影响细菌和人类细胞模型的表型。 | Pizzoccheri, R. | N/A | Pathological PNPase variants with altered RNA binding and degradation activity affect the phenotype of bacterial and human cell models | |
| 通过13个物种的基因组和功能注释进行长链非编码RNA（lncRNA）的跨物种直系同源检测。 | Degalez, F. | N/A | Cross-species orthology detection of long non-coding RNAs (lncRNA) through 13 species using genomic and functional annotations. | |
| 使用ONT R10.4.1长读长测序技术对三种主要呼吸道细菌病原体进行精确基因分型 | Zidane, N. | N/A | Accurate genotyping of three major respiratory bacterial pathogens with ONT R10.4.1 long-read sequencing | |
| 使用蛋白质语言模型进行单序列、无结构的变构残基预测 | Kannan, G. R. | N/A | Single-Sequence, Structure Free Allosteric Residue Prediction with Protein Language Models | |
| 高盐极端微生物核糖体分析中微球菌核酸酶（MNase）的纯化 | Gregorova, P. | N/A | Purification of micrococcal nuclease (MNase) for use in ribosomal profiling of high-salinity extremophiles | |
| 揭示肽核酸作为Riboglow RNA成像平台功能连接体的潜力 | Wierzba, A. J. | N/A | Unveiling the Promise of Peptide Nucleic Acids as Functional Linkers for Riboglow RNA Imaging Platform | |
| 表面非对称机械阻抗下步行的前向模拟：步态康复的启示 | Abdikadirova, B. | N/A | Forward Simulations of Walking on Surfaces with Asymmetric Mechanical Impedance: Insights for Gait Rehabilitation | |
| 蛋白质语言模型的适应性取决于偏好 | Gordon, C. | N/A | Protein Language Model Fitness Is a Matter of Preference | |
| LIET模型：捕捉从加载到终止的RNA聚合酶动力学 | Stanley, J. T. | N/A | LIET Model: Capturing the kinetics of RNA polymerase from loading to termination | |
| 在重构系统中20种氨酰-tRNA合成酶的可持续再生，迈向自合成人工系统 | Hagino, K. | N/A | Sustainable Regeneration of 20 Aminoacyl-tRNA Synthetases in a Reconstituted System Toward Self-Synthesizing Artificial Systems | |
| 高通量优化基于纸张的无细胞生物传感器 | Garcia, D. C. | N/A | High-Throughput Optimization of Paper-Based Cell-Free Biosensors | |
| 巨细胞病毒通过核输出宿主限制因子DDX41来限制先天免疫反应 | Baruah, V. | N/A | Cytomegalovirus Restricts the Innate Immune Response by Nuclear Export of Host Restriction Factor DDX41 | |
| 通过整合系统发育信息，从微生物基因组中改进最大生长速率预测 | Xu, L. | N/A | Improved maximum growth rate prediction from microbial genomes by integrating phylogenetic information | |
| 在丁香假单胞菌中，IS5元件的独立、持续的支系特异性扩张 | Baltrus, D. A. | N/A | Independent, Ongoing Clade-Specific Expansions of IS5 Elements in Pseudomonas syringae | |
| 微生物群落的稳定性与珊瑚的热耐受性相关 | Baquiran, J. I. P. | N/A | Microbiome stability is linked to coral thermotolerance | |
| 含水层微生物群落在热砷迁移作用下表现出高度变异性。 | Chen, M. | N/A | Aquifer microbial communities are highly variable in response to thermal arsenic mobilization | |
| 通过光在哺乳动物细胞中表达生物治疗药物的强效光开关 | Gebel, J. | N/A | Potent photoswitch for expression of biotherapeutics in mammalian cells by light | |
| 百年博物馆标本病毒宏基因组学揭示了RNA的长期稳定性 | Keene, A. H. | N/A | Viral metagenomics of 100-year-old museum specimens highlights the long-term stability of RNA | |
| 考察早期儿童功能性和结构性脑网络架构、年龄与注意力技能之间的关系 | Rokos, L. | N/A | Examining Relationships between Functional and Structural Brain Network Architecture, Age, and Attention Skills in Early Childhood | |
| 引导视觉搜索与早期视觉皮层中的基于特征的优先图相关联。 | Duecker, K. | N/A | Guided Visual Search is associated with a feature-based priority map in early visual cortex | |
| 语义维度支持物体记忆性的皮层表征 | Slayton, M. A. | N/A | Semantic Dimensions Support the Cortical Representation of Object Memorability | |
| 母亲-儿童互动中的同步性：神经与运动耦合作为学龄前儿童运动学习与发展的机制 | Nagy, P. | N/A | Interpersonal Synchronization in Mother-Child Dyads: Neural and Motor Coupling as a Mechanism for Motor Learning and Development in Preschoolers | |
| 皮层中间神经元对浅层感觉处理的可靠性受行为状态的调节 | Sweeney, C. G. | N/A | Reliable sensory processing of superficial cortical interneurons is modulated by behavioral state | |
| 细胞类型特异的投射模式促进皮层微电路中的平衡活动 | Kurth, A. C. | N/A | Cell-type specific projection patterns promote balanced activity in cortical microcircuits | |
| # BioRxiv 2024-10-02 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| MSRP6中一个不寻常的转运域定义了一个复杂结构，该结构对于在感染恶性疟原虫的红细胞中锚定和维持Maurer氏裂隙是必需的。 | Blancke Soares, A. | N/A | An unusual trafficking domain in MSRP6 defines a complex needed for Maurer's clefts anchoring and maintenance in P. falciparum infected red blood cells | |
| 一种基于数据的方法，用于建立细胞运动模式作为巨噬细胞亚型及其与细胞形态关系的预测指标 | Kesapragada, M. | N/A | A data-driven approach to establishing cell motility patterns as predictors of macrophage subtypes and their relation to cell morphology | |
| E4F1 协调丙酮酸代谢与延伸因子复合物的活性，以确保大脑发育过程中翻译的准确性。 | DiMichele, M. | N/A | E4F1 COORDINATES PYRUVATE METABOLISM AND THE ACTIVITY OF THE ELONGATOR COMPLEX TO ENSURE TRANSLATION FIDELITY DURING BRAIN DEVELOPMENT | |
| 簇大小决定人类细胞中转录工厂的形态 | Semeraro, M. | N/A | Cluster size determines morphology of transcription factories in human cells | |
| 抑郁症中的扣带回前下功能连接异常：脑成像大数据与经颅磁刺激精准引导个性化干预的启示 | Chen, X. | N/A | Subgenual Anterior Cingulate Cortex Functional Connectivity Abnormalities in Depression: Insights from Brain Imaging Big Data and Precision-Guided Personalized Intervention via Transcranial Magnetic Stimulation | |
| 构建泛基因组图谱 | Garrison, E. | N/A | Building pangenome graphs | |
| 一种可推广的计算机制，揭示了瞬时渴望与决策之间的相互作用 | Kulkarni, K. R. | N/A | A generalizable computational mechanism underlying the interaction between momentary craving and decision-making | |
| 通过代谢建模实现基于组学的单细胞真核光合生物功能特征定义 | Burel, M. | N/A | Towards an omics-based definition of unicellular eukaryote phototrophs functional traits via metabolic modelling | |
| CD24+CD271+黑色素瘤癌症干细胞具有其单标记对应物的混合特征，并促进侵袭和治疗抗性。 | Knowles, O. | N/A | A CD24+CD271+ Melanoma Cancer Stem Cell Possesses Hybrid Characteristics of its Single Marker Counterparts and Promotes Invasion and Therapeutic Resistance | |
| 在急性刚地弓形虫感染期间，转铁蛋白受体1对于CD4+ T细胞的铁依赖性反应是必需的。 | Denton, S. L. | N/A | Transferrin Receptor 1 is Required for CD4+ T Cell Iron-Dependent Response During Acute Toxoplasma gondii Infection | |
| 分形睡眠周期：一种基于非周期性活动的新型睡眠周期定义 | Rosenblum, Y. | N/A | Fractal cycles of sleep: a new aperiodic activity-based definition of sleep cycles | |
| 精子竞争强度塑造了啮齿动物中精子形态和生殖基因的分化 | Kopania, E. E. K. | N/A | Sperm competition intensity shapes divergence in both sperm morphology and reproductive genes across murine rodents | |
| 在老鼠的上丘中，循环电路编码了视觉中心-周围计算。 | Cui, P. | N/A | Recurrent circuits encode visual center-surround computations in the mouse superior colliculus | |
| 通过时间共享光学镊子微流变学测量细胞器、细胞和生物体的年龄依赖性粘弹性特性 | Catala-Castro, F. | N/A | Measuring age-dependent viscoelastic properties of organelles, cells and organisms via Time-Shared Optical TweezerMicrorheology | |
| MiRGraph：一种混合深度学习方法，通过整合异质调控网络和基因组序列来识别微RNA-靶标相互作用 | Liu, P. | N/A | MiRGraph: A hybrid deep learning approach toidentify microRNA-target interactions by integrating heterogeneous regulatory network and genomic sequences | |
| AptaDiff：基于扩散模型的适配体从头设计与优化 | Wang, Z. | N/A | AptaDiff: de novo design and optimization of aptamers based on diffusion models | |
| 同步呼吸：社会行为如何影响宽吻海豚的呼吸道传染病风险 | Collier, M. A. | N/A | Breathing in sync: how a social behavior structures respiratory epidemic risk in bottlenose dolphins | |
| 磁性细菌的逃逸问题 - 生理磁场强度有助于磁性细菌在模拟沉积物中导航 | Codutti, A. | N/A | Escape problem of magnetotactic bacteria - physiological magnetic field strengths help magnetotactic bacteria navigate in simulated sediments | |
| 努力驱动扫视选择 | Koevoet, D. | N/A | Effort Drives Saccade Selection | |
| 在骨质疏松比格犬模型中使用rhPTH(1-34)和二聚体R25CPTH(1-34)增强骨再生和骨整合 | Shin, J.-O. | N/A | Enhancing Bone Regeneration and Osseointegration using rhPTH(1-34) and Dimeric R25CPTH(1-34) in an Osteoporotic Beagle Model | |
| 一统天下？评估可持续森林管理指标在多分类数据下对生物多样性保护的表现 | Paillet, Y. | N/A | One to rule them all? Assessing the performance of sustainable forest management indicators against multitaxonomic data for biodiversity conservation | |
| 宿主基因型在世代间积极塑造其微生物群 | Benga, L. | N/A | The host genotype actively shapes its microbiome across generations | |
| 马索科湖慈鲷生态型分化过程中重组景观的快速进化 | Talbi, M. | N/A | Rapid evolution of recombination landscapes during the divergence of cichlid ecotypes in Lake Masoko | |
| 违反预测增强了视觉特征在感知中的表征忠实度 | Rideaux, R. | N/A | Violated predictions enhance the representational fidelity of visual features in perception | |
| 大规模基因组测序研究中的高效存储与回归计算 | Rivas, M. A. | N/A | Efficient storage and regression computation for population-scale genome sequencing studies | |
| 配体耦合的环核苷酸门控离子通道中的构象变化通过时间分辨过渡金属离子FRET揭示 | Eggan, P. | N/A | Ligand-Coupled Conformational Changes in a Cyclic Nucleotide-Gated Ion Channel Revealed by Time-Resolved Transition Metal Ion FRET | |
| 使用信息先验来解决存在鉴定错误的占用模型中的识别性问题 | Monchy, C. | N/A | Using informative priors to account for identifiability issues in occupancy models with identification errors | |
| 一种用于慢性脊髓神经调节的主动式电子、高密度硬膜外电极阵列 | Parker, S. R. | N/A | An active electronic, high-density epidural paddle array for chronic spinal cord neuromodulation | |
| 动物社会网络结构驱动因素的因果框架 | Kawam, B. | N/A | A causal framework for the drivers of animal social network structure | |
| 噬菌体展示技术助力机器学习发现癌症抗原特异性T细胞受体 | Croce, G. | N/A | Phage display enables machine learning discovery of cancer antigen specific TCRs | |
| 前额叶和感觉皮层中的预备性注意模板编码了与目标相关的信息。 | Zhou, Z. | N/A | Preparatory attentional templates in prefrontal and sensory cortex encode target-associated information | |
| 骨髓空间转录组学揭示了多发性骨髓瘤细胞结构，伴有功能障碍的T细胞分布、中性粒捕获和中炎性信号传导 | Sudupe, L. | N/A | Bone Marrow Spatial Transcriptomics Reveals a Myeloma Cell Architecture with Dysfunctional T-Cell Distribution, Neutrophil Traps, and Inflammatory Signaling | |
| 选择性烟碱型乙酰胆碱受体亚型的共激活是逆转阿尔茨海默病中海马网络功能障碍和防止恐惧记忆丧失所必需的。 | Lee, R. | N/A | Co-activation of selective nicotinic acetylcholine receptor subtypes is required to reverse hippocampal network dysfunction and prevent fear memory loss in Alzheimer's disease | |
| HERMES：用于突变效应和稳定性预测的全息等变神经网络模型 | Visani, G. M. | N/A | HERMES: Holographic Equivariant neuRal network model for Mutational Effect and Stability prediction | |
| 人类PIEZO1的结构及其缓慢失活的通道病突变体 | Shan, Y. | N/A | Structure of human PIEZO1 and its slow inactivating channelopathy mutants | |
| 在RNA分子池中实现基因组信息的稳定复制 | Burger, L. | N/A | Toward Stable Replication of Genomic Information in Pools of RNA Molecules | |
| 12-脂氧合酶抑制剂可抑制胰岛免疫和炎症反应，并延缓人基因替代小鼠的自身免疫性糖尿病进展。 | Nargis, T. | N/A | 12-Lipoxygenase Inhibition Suppresses Islet Immune and Inflammatory Responses and Delays Autoimmune Diabetes in Human Gene Replacement Mice | |
| 贝叶斯分层模型用于决策标准在试验间波动的研究 | Vloeberghs, R. | N/A | A Bayesian Hierarchical Model of Trial-to-Trial Fluctuations in Decision Criterion | |
| 工程合成激动剂用于靶向激活Notch信号传导 | Perez, D. H. | N/A | Engineering synthetic agonists for targeted activation of Notch signaling | |
| eduWOSM：一款专为教育和研究设计的高级台式显微镜 | Carter, N. J. | N/A | The eduWOSM: a benchtop advanced microscope for education and research | |
| 在不同癌症类型中，以单细胞分辨率和空间背景下解析长链非编码RNA的多样性 | Prakrithi, P. | N/A | Unraveling lncRNA Diversity at a Single Cell Resolution and in a Spatial Context across Different Cancer Types | |
| 小鼠中导致dRTA的SLC4A1突变引起的尿钠丢失和集合管功能紊乱 | Mungara, P. | N/A | Urinary Sodium Wasting and Disrupted Collecting Duct Function in Mice with dRTA-Causing SLC4A1 Mutations | |
| RNA的替代性解码在哺乳动物中产生了稳定且丰富的蛋白质 | Tsour, S. | N/A | Alternate RNA decoding results in stable and abundant proteins in mammals | |
| 肌钙蛋白C突变体中的钙结合亲和力：自由能计算、协同进化建模与机器学习 | Pooja, | N/A | Calcium Binding Affinity in the Mutational Landscape of Troponin-C: Free Energy Calculation, Coevolution modeling and Machine Learning | |
| 适用于快速培养阴道细菌（如惰性乳酸杆菌）及其他阴道细菌的实用培养基配方 | Serrador, D. | N/A | Practical Media Formulations for Rapid Growth of Lactobacillus iners and Other Vaginal Bacteria | |
| CD11B+CD36+细胞是促进骨形成的巨噬细胞，能够限制与年龄相关的骨质流失。 | Koroth, J. | N/A | CD11B+CD36+ cells are bone anabolic macrophages that limit age-associated bone loss | |
| 行为控制的多巴胺基础 | Ballard, I. C. | N/A | A dopaminergic basis of behavioral control | |
| 在斑马鱼神经杆内局部激活光遗传学NMYII会导致远距离、不对称的力传播。 | Crellin, H. A. | N/A | Local optogenetic NMYII activation within the zebrafish neural rod results in long-range, asymmetric force propagation | |
| 一个统一的啮齿动物图谱揭示了背侧迷走复合体的细胞复杂性和进化分歧 | Hes, C. | N/A | A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex | |
| 用于筛选异构化介导酶药物靶点的差分离子迁移声波喷射质谱系统 | Bazargan, S. | N/A | A Differential Ion Mobility Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets | |
| 已撤回：酒石黄无法使活体组织透明化 | Inagaki, S. | N/A | WITHDRAWN: Tartrazine cannot make live tissues transparent | |
| 鉴定出利什曼原虫中一种新型基体定位的ε-微管蛋白 | Seth, A. | N/A | Identification of a novel basal body-localized epsilon-tubulin in Leishmania | |
| 预测透析器选择和吸附剂透析液流速对胆红素清除的影响 | Novokhodko, A. | N/A | Predicting the Impact of Dialyzer Choice and Binder Dialysate Flow Rate on Bilirubin Removal | |
| 实时预测药物诱导的致心律失常风险，采用性别特异性的心脏模拟器 | Dominguez-Gomez, P. | N/A | Real-time prediction of drug-induced proarrhythmic risk with sex-specific cardiac emulators | |
| 开发高效且选择性的CK1α分子胶降解剂 | Geng, Q. | N/A | Development of potent and selective CK1α Molecular Glue Degraders | |
| 运动皮层编码运动学习的神经景观中的分离吸引子 | Liu, X. | N/A | Separated attractors in neural landscape of motor cortex encoding motor learning | |
| 人类协作中的可控性与因果关系 | Spiering, L. | N/A | Controllability and cause in human collaboration | |
| 表观基因组分析揭示了H3K27me3调控人类皮层发育中外基质成分的组成 | Ditzer, N. | N/A | Epigenome profiling identifies H3K27me3 regulation of extra-cellular matrix composition in human corticogenesis | |
| 宿主特异性决定了新的真菌植物病原体种群的出现 | C. Fagundes, W. | N/A | Host specialization defines the emergence of new fungal plant pathogen populations | |
| 快速两步靶标捕获确保了高效的CRISPR-Cas9引导的基因组编辑 | Shi, H. | N/A | Rapid two-step target capture ensures efficient CRISPR-Cas9-guided genome editing | |
| 藿香蓟（Agastache rugosa (Fisch. & C.A.Mey.) Kuntze）的综合生理可塑性揭示了对光和养分梯度的复杂适应性 | Rosli, K. A. | N/A | Integrative physiological plasticity of Agastache rugosa (Fisch. & C.A.Mey.) Kuntze reveals complex adaptation to light and nutrient gradients | |
| 在运动规划中的高效编码 | Wang, T. | N/A | Efficient Coding in Motor Planning | |
| 一种敏感的红/远红光开关，用于在小鼠代谢疾病模型中可控的基因治疗 | Qiao, L. | N/A | A sensitive red/far-red photoswitch for controllable gene therapy in mouse models of metabolic diseases | |
| 捏合与拇指和食指屈曲过程中皮层表面电位的空间和光谱变化 | Kerezoudis, P. | N/A | Spatial and Spectral Changes in Cortical Surface Potentials during Pinching versus Thumb and Index Finger Flexion | |
| 一种新开发的全基因组测序方案使得早期追踪肠道病毒D68的分子进化成为可能。 | Giardina, F. A. | N/A | A newly developed whole genome sequencing protocol enables early tracking of Enterovirus D68 molecular evolution. | |
| 开发一种新型方法制备高功能人类浦肯野网络 | Ji, P. | N/A | Development of a Novel Method to Fabricate Highly Functional Human Purkinje Networks | |
| 肠道微生物群与2型糖尿病关联：16s研究及其方法学挑战的元分析 | Machado, J. | N/A | Gut microbiota and type 2 diabetes associations: A meta-analysis of 16s studies and their methodological challenges | |
| 乳腺癌中FABP4和FABP5的表达特征：临床意义与展望 | Li, B. | N/A | Expression Profiles of FABP4 and FABP5 in Breast Cancer: Clinical Implications and Perspectives | |
| 五人制足球游戏训练对青春期非运动员女孩表现、自我效能、动机及运动成瘾的影响 | Beik, S. | N/A | Effect of Futsal-Based Game Training on Performance, Self-Efficacy, Motivation, and Exercise Addiction in Adolescent Non-Athlete Girls | |
| 将空间扩散纳入突发性随机转录模型中 | Miles, C. E. | N/A | Incorporating spatial diffusion into models of bursty stochastic transcription | |
| 使用二维和三维图像分析工具对成年小鼠脑样本中微胶质细胞形态复杂性进行比较分析 | Murray, C. J. | N/A | A comparison of microglial morphological complexity analysis in adult mouse brain samples using 2-dimensional and 3-dimensional image analysis tools | |
| 使用单细胞和单核测序技术进行可扩展电路映射的高复杂度条形码狂犬病病毒 | Shin, D. | N/A | High-Complexity Barcoded Rabies Virus for Scalable Circuit Mapping Using Single-Cell and Single-Nucleus Sequencing | |
| 长程相互激活在细胞迁移过程中建立Rho和Rac的极性 | De Belly, H. | N/A | Long range mutual activation establishes Rho and Rac polarity during cell migration | |
| 效应异质性揭示了罕见编码变异的复杂多效性效应 | Lu, W. | N/A | Effect heterogeneity reveals complex pleiotropic effects of rare coding variants | |
| 细胞类型指导的镶嵌性局灶性癫痫基因分型揭示了细胞自主性和非细胞自主性疾病相关转录程序 | Bizzotto, S. | N/A | Cell-type-informed genotyping of mosaic focal epilepsies reveals cell-autonomous and non-cell-autonomous disease-associated transcriptional programs | |
| 鉴定与先天性心脏病中临床报告的CNV相关的长非编码RNA候选疾病基因 | Penaloza, J. S. | N/A | Identification of Long Non-coding RNA Candidate Disease Genes Associated with Clinically Reported CNVs in Congenital Heart Disease | |
| 一种综合的蛋白质组和转录组学方法揭示了新的ADAM9底物及其下游通路 | Lu, C. | N/A | An integrative proteotranscriptomics approach reveals new ADAM9 substrates and downstream pathways | |
| 先前报道的90万年前人类祖先的瓶颈期很可能是一个统计学上的假象。 | Deng, Y. | N/A | A previously reported bottleneck in human ancestry 900 kya is likely a statistical artifact | |
| 重复性头部撞击暴露与慢性创伤性脑病的血浆蛋白质组质询 | Saloner, R. | N/A | Interrogating the plasma proteome of repetitive head impact exposure and chronic traumatic encephalopathy | |
| 人口基因组学揭示了非洲本土谷物苔麸（Eragrostis tef）性状改良的位点 | Jones, M. R. W. | N/A | Population genomics uncover loci for trait improvement in the indigenous African cereal tef (Eragrostis tef) | |
| 增强型激酶转位报告系统用于同时实时测量PKA、ERK和Ca2+ | Tsai, S.-J. | N/A | Enhanced kinase translocation reporters for simultaneous real-time measurement of PKA, ERK, and Ca2+ | |
| 调节ATP-腺苷信号轴结合放射治疗促进脑转移中的抗癌免疫 | Salamero-Boix, A. | N/A | Modulation of the ATP-adenosine signaling axis combined with radiotherapy facilitates anti-cancer immunity in brain metastasis | |
| 基于细胞提取物的体外DNA复制能够实现可持续的无细胞基因表达 | Zheng, X. | N/A | Cell extract-based in vitro DNA replication enables sustainable cell-free gene expression | |
| 扩展莱茵衣藻倍性操作工具箱 | Van de Vloet, A. | N/A | Expanding the toolkit for ploidy manipulation in Chlamydomonas reinhardtii | |
| 布尔网络吸引子景观的映射 | Trinh, V.-G. | N/A | Mapping the attractor landscape of Boolean networks | |
| 小鼠背侧梨状皮层核的全脑连接和新奇反应 | Manjila, S. B. | N/A | Brain-wide connectivity and novelty response of the dorsal endopiriform nucleus in mice | |
| 经验塑造了嗅觉表征沿着皮层-海马路径的转变 | Eleonore, S. | N/A | Experience shapes the transformation of olfactory representations along the cortico-hippocampal pathway | |
| B细胞c-Maf信号在胰腺癌和黑色素瘤的动物模型中促进肿瘤进展 | Zhong, Q. | N/A | B cell c-Maf signaling promotes tumor progression in animal models of pancreatic cancer and melanoma | |
| SIRT4通过增强NK细胞对肝星状细胞的细胞毒性，并通过AMPKα/P-p53/NKG2DL途径逆转肝纤维化。 | Zhang, F. | N/A | SIRT4 enhances the cytotoxicity of NK cells toward hepatic stellate cells and reverses liver fibrosis via AMPKα/P-p53/NKG2DL pathway | |
| RNA结合蛋白Musashi1与病毒基因组RNA相互作用，并通过抑制翻译来限制SARS-CoV-2感染。 | Ganguli, S. | N/A | RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translation | |
| 阿塔卡马沙漠的土壤生物多样性在不同多样性水平上呈现出明显的模式。 | Villegas, L. | N/A | Soil biodiversity in the Atacama Desert shows distinct patterns at different diversity levels | |
| 使用对比学习进行遗传数据降维 | Thor, F. | N/A | Dimensionality Reduction of Genetic Data using Contrastive Learning | |
| 酵母中的rDNA拷贝数变异会改变对环境条件的响应 | Thornton, K. | N/A | rDNA copy number variation in yeast alters response to environmental conditions | |
| 质子通道失活导致叶绿体NDH复合物活性丧失 | Strand, D. D. | N/A | Proton channel inactivation results in loss of chloroplast NDH complex activity | |
| 持续接触多价抗原修饰的纳米颗粒会产生广泛的抗冠状病毒反应。 | Baillet, J. | N/A | Sustained exposure to multivalent antigen-decorated nanoparticles generates broad anti-coronavirus responses | |
| 单细胞核测序揭示肾上腺皮质癌中的复制应激 | Popova, L. V. | N/A | Single Nuclei Sequencing Reveals Replication Stress in Adrenocortical Carcinoma | |
| 来自中国新疆上侏罗纪齐古组的新剑龙（恐龙纲：鸟臀目）及其对中国剑龙类系统发育的修订 | Li, N. | N/A | A new stegosaur (Dinosauria: Ornithischia) from the Upper Jurassic Qigu Formation of Xinjiang, China and a revision on Chinese stegosaurs phylogeny | |
| 神经分化型内皮细胞亚型调控器官血流与免疫平衡 | Gyarmati, G. | N/A | Neuronally differentiated endothelial cell subtype regulates organ blood flow and immune balance | |
| 基于合成细胞的组织用于自下而上组装人工淋巴器官 | Burgstaller, A. | N/A | Synthetic cell-based tissues for bottom-up assembly of artificial lymphatic organs | |
| 利用多模态网络数据整合与分析解码帕金森病变异体间的共享分子失调 | Zagare, A. | N/A | Deciphering shared molecular dysregulation across Parkinson's disease variants using a multi-modal network-based data integration and analysis | |
| 海洋杜父鱼配对鳍上的表皮微结构为支撑底栖固着机制提供了新的见解。 | Kane, E. A. | N/A | Epidermal microstructures on the paired fins of marine sculpins provide new insights into mechanisms supporting benthic station-holding | |
| 多重功能分析TAP2变体在调节MHC-I细胞表面丰度中的作用揭示了PLK1的过度表达下调抗原呈递。 | Nagy, G. | N/A | Multiplexed functional analysis of TAP2 variants in regulating MHC-I cell surface abundance reveals overexpression of PLK1 downregulates antigen presentation. | |
| 增加CPT1a表达是对病理应激的关键心脏保护性反应，它抑制了重塑基因程序，并使通过基因转移进行拯救成为可能。 | Carley, A. N. | N/A | Increased CPT1a expression is a critical cardioprotective response to pathological stress that suppresses gene programs for remodeling and enables rescue by gene transfer | |
| 癫痫的破伤风毒素模型中突触异质性降低：计算模型提供的见解 | Zarei Eskikabd, P. | N/A | Reduced Synaptic Heterogeneity in a Tetanus ToxinModel of Epilepsy: Insights from ComputationalModeling | |
| 在高度视觉化的动物中，通过注视远程激活地点代码 | Payne, H. L. | N/A | Remote activation of place codes by gaze in a highly visual animal | |
| 神经代谢物T1弛豫时间的年龄依赖性 | Murali-Manohar, S. | N/A | Age dependency of neurometabolite T1 relaxation times | |
| 自噬增强剂在额颞叶痴呆的干细胞模型中挽救了Tau蛋白的积累 | Mirfakhar, F. | N/A | Autophagic enhancer rescues Tau accumulation in a stem cell model of frontotemporal dementia | |
| 循环蛋白塑造小胶质细胞状态并增强吞噬作用 | Lu, N. | N/A | Circulatory proteins shape microglia state and boost phagocytosis | |
| 单细胞RNA测序揭示了小鼠和大鼠母体向合子过渡的早期转录程序 | Su, Y. | N/A | Single-cell RNA-seq Reveals Early Transcriptional Programs of the Maternal to Zygote Transition in Mice and Rats | |
| 各向异性拉伸使多细胞水螅聚集体中的肌动蛋白纤维自组织产生偏倚 | Bailles, A. | N/A | Anisotropic stretch biases the self-organization of actin fibers in multicellular Hydra aggregates | |
| 一种可持续且由蜜蜂授粉的咖啡，为你的一天拉开序幕 | Alves, D. A. | N/A | A sustainable and bee-pollinated coffee to start your day | |
| 新生代进化史掩盖了棘鳍鱼类在中生代的起源。 | Brownstein, C. D. | N/A | Cenozoic evolutionary history obscures the Mesozoic origins of acanthopterygian fishes | |
| 在极端代谢适应下的三维基因组组织表现出基因组区室化和环状结构的变化。 | Biswas, T. | N/A | 3D genome organization under extreme metabolic adaptation shows variations in genome compartmentalization and looping | |
| 一种新的古菌遗传密码的零星分布，其中所有TAG密码子均编码吡咯赖氨酸 | Kivenson, V. | N/A | Sporadic distribution of a new archaeal genetic code with all TAG codons as pyrrolysine | |
| 分析桉油精、柠檬烯和蒎烯肠溶胶囊（QIENUO）治疗肺囊性纤维化的分子机制：网络药理学研究与分子对接验证 | Tiantaixi, T. | N/A | Analyzing the Molecular Mechanism of Eucalyptol, Limonene and Pinene Enteric Capsules (QIENUO) in the Treatment of Pulmonary cystic fibrosis with Network Pharmacology and Verifying Molecular Docking | |
| 通过整合序列和结构特征，增强蛋白质功能身份的预测 | Fujita, S. | N/A | Enhanced prediction of protein functional identity through the integration of sequence and structural features | |
| 突变型IDH使p53与靶基因调控分离，从而抑制肿瘤抑制功能 | Martin, C. P. | N/A | Mutant IDH uncouples p53 from target gene regulation to disable tumor suppression | |
| 通过罗望子果实果肉乙醇提取物减轻氟化钠处理对Wistar大鼠生殖功能的抑制作用 | Usman, L. A. | N/A | Mitigation of Reproductive Function in Sodium Fluoride-administered Wistar Rats by Tamarindus indica Fruit Pulp Ethanol Extract | |
| 探索新领域：一种新型Cdk5抑制剂恢复认知功能并缓解2型糖尿病 | Paul, S. | N/A | Exploring New Horizons:A Novel Cdk5 Inhibitor Restoring Cognitive Function and Alleviating Type 2 Diabetes. | |
| 社会性塑造了支持低氧耐受性的线粒体适应 | Rossi, A. | N/A | Sociality shapes mitochondrial adaptations supporting hypoxia tolerance | |
| 内皮下钙化增加表面粗糙度，并促进脂质沉积到动脉壁中。 | Kosciuszek, N. D. | N/A | Subendothelial Calcification Increases Surface Roughness and Promotes Lipid Deposition into the Arterial Wall | |
| 后顶叶皮层调节前额眼区中的内在神经时间尺度和注意处理 | Soyuhos, O. | N/A | Posterior Parietal Cortex Regulates Intrinsic Neural Timescales and Attentional Processing in Frontal Eye Field | |
| SARM1的缺失可防止常染色体显性视神经萎缩中的视网膜神经节细胞退化。 | Ding, C. | N/A | Loss of SARM1 protects against retinal ganglion cell degeneration in Autosomal Dominant Optic Atrophy | |
| Galnt2神经元丢失损害O-糖基化并导致模拟GALNT2-CDG的神经行为缺陷 | Edmondson, A. C. | N/A | Neuronal loss of Galnt2 Impairs O-glycosylation and Leads to Neurobehavioral Deficits Mimicking GALNT2-CDG | |
| 前丘脑中与心率相关的活动在相位性和紧张性快速眼动睡眠期间有所不同。 | Simor, P. | N/A | Heartbeat related activity in the anterior thalamus differs between phasic and tonic REM sleep periods | |
| 双特异性磷酸酶3（Dual Specificity Phosphatase 3）的敲低促使髓系白血病细胞分化为巨噬细胞并极化。 | Farias, J. O. | N/A | Dual Specificity Phosphatase 3 knockdown drives myeloid leukemia cells to differentiate into macrophages and polarize | |
| 人胰腺导管类器官中的旋转迁移依赖于肌动蛋白和肌球蛋白的活性。 | Xie, G. | N/A | Rotational migration in human pancreatic ductal organoids depends on actin and myosin activity | |
| 评估跨平台归一化方法以进行综合微阵列和RNA测序数据分析 | Sun, X. | N/A | Evaluating Cross-Platform Normalization Methods for Integrated Microarray and RNA-seq Data Analysis | |
| 微通道内增强的细菌趋化性：在通道宽度与圆形游泳半径匹配时达到最佳性能 | Yue, C. | N/A | Enhanced bacterial chemotaxis in confined microchannels: Optimal performance in lane widths matching circular swimming radius | |
| 年龄相关性的PDE11A4蛋白表达增加会触发酶的液-液相分离（LLPS），而这种相分离可以通过PDE11A4小分子抑制剂逆转。 | Amurrio, E. | N/A | Age-related increases in PDE11A4 protein expression trigger liquid:liquid phase separation (LLPS) of the enzyme that can be reversed by PDE11A4 small molecules inhibitors | |
| 认知控制中的前摄、反应和注意动态的计算建模 | Mistry, P. K. | N/A | Computational Modeling of Proactive, Reactive, and Attentional Dynamics in Cognitive Control | |
| FB5P-seq-mAbs：从FB5P-seq库中制备单克隆抗体，用于B细胞的整合单细胞分析 | Ado, S. | N/A | FB5P-seq-mAbs: monoclonal antibody production from FB5P-seq libraries for integrative single-cell analysis of B cells | |
| Spc105-Kre28复合体通过外侧动粒招募Ipl1/Aurora B激酶促进有丝分裂错误校正 | Dudziak, A. | N/A | The Spc105-Kre28 complex promotes mitotic error correction by outer kinetochore recruitment of the Ipl1/Aurora B kinase | |
| UBR-1缺乏导致C. elegans对伊维菌素的抗性 | Li, Y. | N/A | UBR-1 deficiency leads to ivermectin resistance in C. elegans | |
| 拓扑异构酶2B和核纤层B受体协同调控基因组与核纤层相互作用 | Manzo, S. G. | N/A | Coordinated control of genome-nuclear lamina interactions by Topoisomerase 2B and Lamin B receptor | |
| IgBlend：在抗体语言模型中统一三维结构和序列 | Malherbe, C. | N/A | IgBlend: Unifying 3D Structures and Sequences in Antibody Language Models | |
| 基于模拟的推断中更优的置信区间 | Rousset, F. | N/A | Better confidence intervals in simulation-based inference | |
| 微缩图：无监督地将多重组织成像数据集的缩略图作为数据门户的预览 | Taylor, A. J. | N/A | Miniature: Unsupervised glimpses into multiplexed tissue imaging datasets as thumbnails for data portals | |
| PHLOWER - 使用Hodge拉普拉斯分解进行单细胞轨迹分析 | Cheng, M. | N/A | PHLOWER - Single cell trajectory analysis using Decomposition of the Hodge Laplacian | |
| LINE-1核糖核蛋白复合物通过与DNA结合，在有丝分裂期间促进核内进入。 | Zernia, S. | N/A | LINE-1 ribonucleoprotein complexes bind DNA to enable nuclear entry during mitosis | |
| 探究烃类交联剂对p53钉合肽结构及结合能力的影响 | Choudhury, A. R. | N/A | Exploring the effect of Hydrocarbon Cross-linkers on the Structure and Binding of Stapled p53 Peptides | |
| N-乙酰-2-氨基芴（AAF）：通过来自多周期肝致癌性喂养方案的癌前肝细胞原代培养，揭示了生长周期依赖性大分子结合常数KD的体内时间表达模式 | Koch, K. S. | N/A | N-Acetyl-2-Aminofluorene (AAF): In vivo temporal expression patterns of growth cycle-dependent macromolecular binding constants KD are revealed by primary cultures of premalignant hepatocytes derived from a multi-cyclic hepatocarcinogenic feeding regimen | |
| 通过动力学分类实现可调的配体辨别 | Dixit, P. D. | N/A | Tunable ligand discrimination via kinetic sorting | |
| 单细胞通过“异或”和“不等于”逻辑在二聚体中识别非自我与自我 | An, R. | N/A | Single Cells Signal Non-self from Self via 'XOR' and 'NOT EQUALS' Logic in a Dimer of Dimers | |
| 使用肌电图进行可泛化的手势识别 | Yun, R. | N/A | Generalizable gesture recognition usingmagnetomyography | |
| 利用肌电图进行可泛化的手势识别 | Yun, R. | N/A | Generalizable gesture recognition usingmagnetomyography | |
| 快速眼动睡眠期间θ频带活动的时空模式：一项脑磁图分析 | Provias, V. | N/A | Spatiotemporal patterns of theta-band activity during rapid-eye movement sleep: a magnetoencephalography analysis | |
| 在Dravet综合征的小鼠模型中，表达Parvalbumin的中间神经元的异位动作电位发放显著减弱。 | Hill, S. F. | N/A | Attenuated ectopic action potential firing in parvalbumin expressing interneurons in a mouse model of Dravet Syndrome | |
| 使用各向同性ADC-fMRI技术绘制人脑灰质和白质活动图 | Spencer, A. P. C. | N/A | Mapping grey and white matter activity in the human brain with isotropic ADC-fMRI | |
| 一项针对与精神分裂症相关基因的果蝇筛选研究强调了神经和胶质细胞中的基质金属蛋白酶在神经重塑中的必要性。 | Keret, S. | N/A | A Drosophila screen of schizophrenia-related genes highlights the requirement of neural and glial matrix metalloproteinases for neuronal remodeling | |
| 自适应时空框架用于自动E/MEG源成像 | Feng, Z. | N/A | STARTS: A self-adapted spatio-temporal framework for automatic E/MEG source imaging | |
| 历史偏差及其对猕猴前额叶皮层刺激表征的扰动。 | Benozzo, D. | N/A | History bias and its perturbation of the stimulus representation in the macaque prefrontal cortex. | |
| 利用牵张反射模型从肌电图（EMG）中估计快速和慢速运动中的下行激活模式 | Zhang, L. | N/A | Estimating descending activation patterns from EMG in fast and slow movements using a model of the stretch reflex | |
| 使用自动编码器生成信号和ResNet分类的脑刺激伪影鲁棒检测 | Saal, J. | N/A | Robust Detection of Brain Stimulation Artifacts in iEEG Using Autoencoder-Generated Signals and ResNet Classification | |
| 多样化的钙动力学支撑着海马CA1锥体细胞中位置场的形成 | Sumegi, M. | N/A | Diverse calcium dynamics underlie place field formation in hippocampal CA1 pyramidal cells | |
| 验证运动校正后的MPRAGE与常规MPRAGE在儿童形态学分析中的一致性 | Gal-Er, B. | N/A | Verifying the concordance between motion corrected and conventional MPRAGE for pediatric morphometric analysis | |
| 计算建模揭示了神经生物学对静态和动态功能连接模式的贡献 | Hoheisel, L. | N/A | Computational modelling reveals neurobiological contributions to static and dynamic functional connectivity patterns | |
| 稳定的Netrin-1荧光报告鸡揭示了视裂闭合过程中细胞特异性的分子特征。 | Chan, B. H. C. | N/A | A stable Netrin-1 fluorescent reporter chicken reveals cell-specific molecular signaturesduring optic fissure closure. | |
| 林地驯鹿在危险栖息地的社会促进作用：对火灾和道路的反应 | Hendrix, J. G. | N/A | Social facilitation of risky habitats in woodland caribou: responses to fire and roads | |
| 对存在采样强度偏差和删失的动物网络进行稳健贝叶斯分析 | Sosa, S. | N/A | Robust Bayesian analysis of animal networks subject to biases in sampling intensity and censoring | |
| 竞争排斥、基于经验的学习以及人类捕捞活动，对幼年及成年褐鹈鹕（Pelecanus occidentalis）的活动模式产生影响。 | Plazas-Cardona, D. | N/A | Competitive exclusion, experience-based learning, and human fishing, influence activity patterns in Juvenile and Adult Brown Pelicans (Pelecanus occidentalis) | |
| 通过异质OATP-配体相互作用图神经网络（HOLI-GNN）预测OATP1B1抑制剂 | Mardikoraem, M. | N/A | Predicting Inhibitors of OATP1B1 via Heterogeneous OATP-Ligand Interaction Graph Neural Network (HOLI-GNN) | |
| 三维微结构的快速原型制作：一种简化的灰度光刻编码方法，使用Blender软件实现 | Borghi, F. F. | N/A | Rapid Prototyping of 3D Microstructures: A Simplified Grayscale Lithography Encoding Method Using Blender | |
| 利用工程化病毒样颗粒进行活细胞转录组学 | Najia, M. A. | N/A | Live-cell transcriptomics with engineered virus-like particles | |
| ClassiCOL：通过胶原蛋白肽模糊性进行古代物种分类的LC-MS/MS分析 | Engels, I. | N/A | ClassiCOL: LC-MS/MS analysis for ancient species Classification via Collagen peptide ambiguation | |
| 关于残基D1-V185在Synechocystis 6803和Thermosynechococcus vestitus中光系统II功能中的作用的新见解。 | BOUSSAC, A. | N/A | New insights into the involvement of residue D1-V185 in Photosystem II function in Synechocystis 6803 and Thermosynechococcus vestitus. | |
| mTOR信号通过3'UTR介导的翻译控制促进T细胞中的细胞因子产生 | Jurgens, A. P. | N/A | mTOR signaling promotes cytokine production in T cells through 3UTR-mediated translation control | |
| 阴道毛滴虫胞外囊泡抑制IFNϵ介导的对宿主细胞溶解的保护作用 | Kochanowsky, J. A. | N/A | Trichomonas vaginalis extracellular vesicles suppress IFNϵ-mediated protection against host cell cytolysis | |
| 凝胶内重折叠使得在SDS-PAGE后能够对完全变性的GFP进行荧光检测。 | Shiratori, M. | N/A | In-gel refolding allows fluorescence detection of fully denatured GFPs after SDS-PAGE | |
| G4停滞的CMG的冷冻电镜结构揭示了DNA易位的尺蠖机制 | Batra, S. | N/A | Cryo-EM structures of G4-stalled CMG reveal inchworm mechanism of DNA translocation | |
| 致癌蛋白TEL-ABL的自磷酸化使其对变构ABL抑制剂阿西米尼产生耐药性。 | Muratcioglu, S. | N/A | Autophosphorylation of the oncogenic protein TEL-ABL confers resistance to the allosteric ABL inhibitor asciminib | |
| 工程化合成多价VHH抗体识别SARS-Cov-2刺突蛋白的结构基础 | Lujan Hernandez, A. G. | N/A | Structural basis of SARS-Cov-2 spike recognition by engineered synthetic multivalent VHH antibodies | |
| 一种经过工程改造的染色质蛋白，增强了其对H3K27me3相对于H3K9me3的优先结合能力 | Franklin, K. A. | N/A | An engineered chromatin protein with enhanced preferential binding of H3K27me3 over H3K9me3 | |
| 利用冈比亚按蚊密度病毒（AgDNV）内含子表达系统表达冈比亚按蚊内源性微小RNA | Johnson, R. M. | N/A | Expression of endogenous Anopheles gambiae microRNAs using an Anopheles gambiae densovirus (AgDNV) intronic expression system | |
| 软X射线断层扫描揭示了在tasA缺失后B.subtilis生物膜结构的变异 | Chatzimpinou, A. | N/A | Soft X-ray tomography reveals variations in B.subtilis biofilm structure upon tasA deletion | |
| 疟原虫运动中的牵引力生成受疟原虫粘附蛋白TLP的调节。 | Ripp, J. | N/A | Traction force generation in motile malaria parasites is modulated by the Plasmodium adhesin TLP | |
| 从太平洋牡蛎中分离得到的加利西亚单胞菌（Gallaecimonas pentaromativorans）10A株的基因组显示了其降解碳氢化合物和CRISPR-Cas防御的潜力。 | Gouin, Y. | N/A | The genome of Gallaecimonas pentaromativorans strain 10A, isolated from a Pacific oyster, reveals the potential for hydrocarbon degradation and CRISPR-Cas defense | |
| 种间系统生物学将细菌代谢途径与线虫的基因表达、行为和生存联系起来。 | Athanasouli, M. | N/A | Interspecies systems biology links bacterial metabolic pathways to nematode gene expression, behavior, and survival | |
| 刚地弓形虫PROP1在慢性感染期间对自噬和寄生虫存活至关重要 | Thaprawat, P. | N/A | Toxoplasma gondii PROP1 is critical for autophagy and parasite viability during chronic infection | |
| 土壤深度决定了高粱田中的微生物群落 | Murray, E. R. | N/A | Soil depth determines the microbial communities in Sorghum bicolor fields | |
| 核糖体蛋白的过度表达导致大肠杆菌对锌产生抗性 | Kosaki, T. | N/A | Overexpression of Ribosomal Proteins Leads to Zn Resistance in Escherichia coli | |
| 内部框架翻译产生Cas11b，这对于古菌CRISPR-Cas系统中的有效干扰至关重要。 | Sailer, A.-L. | N/A | Internal in-frame translation generates Cas11b, which is important for effective interference in an archaeal CRISPR-Cas system | |
| MukBEF SMC复合物捕获DNA的机制及其被病毒DNA模拟物抑制的机制 | Bürmann, F. | N/A | Mechanism of DNA entrapment by the MukBEF SMC complex and its inhibition by a viral DNA mimic | |
| 纳米纹理钢表面具有抗真菌活性 | Tripathi, A. | N/A | Nanotextured steel surface exhibits antifungal activity | |
| 环境中的多硫化物促进在厌氧条件下生长的微生物的蛋白质二硫键形成。 | Liu, H. | N/A | Environmental polysulfides promote protein disulfide bond formation of microorganisms growing under anaerobic condition | |
| 基因组范围内体内动态的cohesin介导的环挤压及其在转录激活中的作用 | Popay, T. M. | N/A | Genome-wide in vivo dynamics of cohesin-mediated loop extrusion and its role in transcription activation | |
| 基于转录组的全基因组范围内鉴定冈比亚按蚊的长非编码RNA（lncRNA） | Xu, J. | N/A | Transcriptome-based identification of long noncoding RNAs (lncRNAs) across the genome of Anopheles gambiae | |
| 综合多组学特征揭示了绝经后人类卵巢中阿霉素诱导的细胞衰老。 | Devrukhkar, P. R. | N/A | A comprehensive multi-omics signature of doxorubicin-induced cellular senescence in the postmenopausal human ovary. | |
| MORC-1是秀丽隐杆线虫（C. elegans）CSR-1生殖系基因许可机制的关键组成部分。 | Kirshner, J. A. | N/A | MORC-1 is a key component of the C. elegans CSR-1 germline gene licensing mechanism | |
| 早期干预使用低剂量硬化蛋白抗体治疗可减少卵巢切除大鼠初始骨丢失后由成骨细胞介导的继发性矿化 | Naqvi, S. M. | N/A | Early Intervention with Low-Dose Sclerostin Antibody Therapy can Reduce Osteocyte-mediated Secondary Mineralization after initial bone loss in Ovariectomised Rats | |
| VCP、VCPIP1 和 p47 的三元复合物形成促进了高尔基体的重新组装。 | Shah, B. | N/A | Ternary complex formation of VCP, VCPIP1 and p47 facilitates Golgi reassembly | |
| inPhase - 一种简单、准确且快速的方法来确定蛋白质凝聚相图 | Fritsch, A. W. | N/A | inPhase - A simple, accurate and fast approach to determine phase diagrams of protein condensates | |
| 西西米迪蒂斯：具有锌-四半胱氨酸模体和天冬酰胺酰化的RiPPs | Zhu, A. | N/A | Cysimiditides: RiPPs with a Zn-tetracysteine motif and aspartimidylation | |
| 从共同的前生物激活中间体中，肽和RNA的交叉催化增强 | Roy, R. | N/A | Cross-catalytic enhancement of peptides and RNA from a common prebiotic activated intermediate | |
| 丘脑室旁核中垂体腺苷酸环化酶激活多肽（PACAP）的过度表达改变了雌性大鼠的动机和情感行为 | Carpenter, B. A. | N/A | Pituitary adenylate cyclase-activating polypeptide (PACAP) overexpression in the paraventricular nucleus of the thalamus alters motivated and affective behavior in female rats | |
| 视觉特征注意控制的分层组织 | Meyyappan, S. | N/A | Hierarchical Organization of Visual Feature Attention Control | |
| 在思想的连续流动中，自发记忆回忆和未来思考的神经动力学 | Su, H. | N/A | Neural dynamics of spontaneous memory recall and future thinking in the continuous flow of thoughts | |
| 致病相关脑膜炎奈瑟菌丝状噬菌体MDA{varphi}的结构 | Boehning, J. | N/A | Structure of the virulence-associated Neisseria meningitidis filamentous bacteriophage MDA{varphi} | |
| Meru 协调纺锤体取向与细胞极性和细胞周期进程 | McLellan, M. M. | N/A | Meru co-ordinates spindle orientation with cell polarity and cell cycle progression | |
| 一种用于跨物种小脑发育比较研究的最低限度引导类器官模型 | Guglielmi, L. | N/A | A minimally guided organoid model for cross-species comparisons of cerebellar development | |
| 逐步、模块化的均一大脑类器官设计，代表神经元与胶质细胞之间动态的细胞相互作用 | Kim, E. | N/A | A stepwise, modular design of building uniform brain assembloids representing the dynamic cellular interplay between neurons and glial cells | |
| 对听觉反馈操作的敏感性和个体差异 | Ozker, M. | N/A | Susceptibility to auditory feedback manipulations and individual variability | |
| 导致智力障碍的KIF11基因突变会损害微管动力学和树突分支 | Wingfield, J. L. | N/A | Intellectual disability-causing mutations in KIF11 impair microtubule dynamics and dendritic arborization | |
| 纹状体的调节支持特定策略的强化，而非动作选择 | Hodge, A. T. | N/A | Striatal modulation supports policy-specific reinforcement and not action selection | |
| # BioRxiv 2024-10-01 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 一项miRNA筛选发现了一个调控成年干细胞命运的转录程序 | Robert, J. | N/A | A miRNA screen identifies a transcriptional program controlling the fate of adult stem cell | |
| Cul3泛素连接酶通过与Insomniac作为适配器相互作用，影响睡眠和突触稳态。 | Li, Q. | N/A | The Cul3 ubiquitin ligase engages Insomniac as an adaptor to impact sleep and synaptic homeostasis | |
| Swi6/HP1与siRNA-DNA杂交体的H3-K9-me非依赖性结合在小孢子酵母中启动了在同源dg-dh重复序列处的异染色质组装 | Singh, J. | N/A | An H3-K9-me-independent binding of Swi6/HP1 to siRNA-DNA hybrids initiates heterochromatin assembly at cognate dg-dh repeats in Fission Yeast | |
| 深度学习和跨物种分析揭示了性别和大麻素信号传导对小脑蚓部形态的影响 | Black, K. C. | N/A | Deep learning and cross-species analysis identify the influences of sex and cannabinoidsignaling on cerebellar vermis morphology | |
| SATB1通过结合到碱基不配对区域（BURs）来组织基因组，为SATB1调控的基因表达提供支架。 | Kohwi, Y. | N/A | Genome organization by SATB1 binding to base-unpairing regions (BURs) provides scaffold for SATB1-regulated gene expression | |
| 更年期男性？对果蝇进行的伴侣选择理论实验验证表明，两性都可能经历更年期 | Purohith, D. | N/A | Men in menopause? Experimental verification of the mate choice theory with Drosophila melanogaster shows both sexes can undergo menopause | |
| 高曝光度差异使得在小规模甲基汞暴露的秘鲁成年人EWAS中能够检测到候选生物标志物 | Weinhouse, C. | N/A | High exposure variance enables candidate biomarker detection in a small EWAS of methylmercury-exposed Peruvian adults | |
| 大鼠非桶状体感皮层的建模与仿真。第一部分：解剖建模 | Reimann, M. W. | N/A | Modeling and Simulation of Rat Non-Barrel Somatosensory Cortex. Part I: Modeling Anatomy | |
| 基于模型的压缩感知实现了从全息集合刺激中快速学习神经回路 | Triplett, M. A. | N/A | Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing | |
| 全脑范围的突触蛋白周转测量揭示了学习过程中局部可塑性的存在 | Mohar, B. | N/A | Brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning | |
| 有其母必有其女？孤雌生殖黄蜂体型表型可塑性、环境协变及遗传力研究 | Tovar, A. | N/A | Like mother, like daughter? Phenotypic plasticity, environmental covariation, and heritability of size in a parthenogenetic wasp | |
| 多蛋白信号复合物维持AKT和mTOR/S6K活性，这对处于压力下的癌细胞的生存是必需的。 | Teran Pumar, O. Y. | N/A | A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress | |
| PRDM16在BMP通路中作为共抑制因子，抑制神经干细胞的增殖。 | He, L. | N/A | PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation | |
| 预测内在无序蛋白质的序列依赖性骨架动力学 | Qin, S. | N/A | Predicting the Sequence-Dependent Backbone Dynamics of Intrinsically Disordered Proteins | |
| 单核细胞毒素引起破坏性的Sec61依赖性内皮糖萼和血管基底膜丧失：结核分枝杆菌感染中驱动组织坏死的新间接机制 | Hsieh, L. T.-H. | N/A | Mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection | |
| 全脑血容量变化驱动人类宏观脑脊液流动 | Zimmermann, J. | N/A | Total cerebral blood volume changes drive macroscopic cerebrospinal fluid flux in humans | |
| Detect+Track：用于改进鱼类跟踪和行为分析的稳健且灵活的软件工具 | Dutta, A. | N/A | Detect+Track: Robust and flexible software tools for improved tracking and behavioural analysis of fish | |
| 通过从整体到单细胞的反卷积方法，分析白血病干细胞的药物敏感性 | Alexandre, C. | N/A | Profiling drug sensitivity of leukemic stem cells via bulk-to-single-cell deconvolution | |
| 代谢网络中切换节点的计算机模拟识别 | Mairet, F. | N/A | In silico identification of switching nodes in metabolic networks | |
| 肌动蛋白-TFII-IΔ通过形态力学调节ERK的调谐，调控细胞身份 | Wu, Q. | N/A | Morphomechanic tuning of ERK by actin-TFII-IΔ regulates cell identity | |
| 在有限时间内进行高效的数量估计 | Heng, J. A. | N/A | Efficient numerosity estimation under limited time | |
| 系统比较了用于表达预测的计算方法 | Kernfeld, E. | N/A | A systematic comparison of computational methods for expression forecasting | |
| 结合视频遥测和可穿戴式MEG进行自然主义成像 | O'Neill, G. C. | N/A | Combining video telemetry and wearable MEG for naturalistic imaging | |
| 长期光生物调节对小鼠衰老的治疗效果 | Ahmet, I. | N/A | The Therapeutic Effects of Long-term Photobiomodulation on Aging in Mice | |
| 推进蛋白质-DNA结合位点预测：整合序列模型与机器学习分类器 | Murad, T. | N/A | Advancing Protein-DNA Binding Site Prediction: Integrating Sequence Models and Machine Learning Classifiers | |
| 孕酮通过两个具有PLA2活性的必需共受体诱导减数分裂 | Nader, N. | N/A | Progesterone induces meiosis through two obligate co-receptors with PLA2 activity | |
| Kdm6a和Kdm6b在调节哺乳动物神经再生中的作用 | Yang, S.-G. | N/A | Roles of Kdm6a and Kdm6b in regulation of mammalian neural regeneration | |
| 通过依赖泛素化的TEAD降解靶向癌症中的Hippo通路 | Pham, T. H. | N/A | Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation | |
| SARS-CoV-2刺突抗体与登革病毒发生交叉反应，并在体外和体内增强感染 | Jakhar, K. | N/A | SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection in-vitro and in-vivo | |
| STING 通过 HOIP 介导的 M1 泛素链合成来刺激 NFkB 信号传导 | Fischer, T. D. | N/A | STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NFkB signaling | |
| 互助主义者提供的资源增加了对寄生虫的易感性 | Yi, E. | N/A | Mutualist-Provided Resources Increase Susceptibility to Parasites | |
| 人类第二视觉区域中颜色、视差和自然纹理的中尺度功能组织与连接性 | Ai, H. | N/A | Mesoscale functional organization and connectivity of color, disparity, and naturalistic texture in human second visual area | |
| 优化Niosome制剂以增强细胞应用：与L-α-卵磷脂脂质体的比较案例研究 | Cakir, N. | N/A | Optimizing Niosome Formulations for Enhanced Cellular Applications: A Comparative Case Study with L-α-lecithin Liposomes | |
| 一种高效的计算方法，用于生成具有常染色体三体的阳性NIPT样本 | Nguyen Huy, T. | N/A | An Efficient Computational Method to Create Positive NIPT Samples with Autosomal Trisomy | |
| 量化分层肌肉相互作用对运动功能的多样化贡献 | O'Reilly, D. | N/A | Quantifying the diverse contributions of hierarchical muscle interactions to motor function | |
| 在站立平衡过程中皮质对姿势摇摆的追踪。 | Legrand, T. | N/A | Cortical tracking of postural sways during standing balance. | |
| 利用scATAC-seq在不同免疫细胞类型和背景下对eQTL和哮喘风险位点进行功能性表征 | Wei, J. | N/A | Functional characterization of eQTLs and asthma risk loci with scATAC-seq across immune cell types and contexts | |
| 诱导后的幂律行为短暂存在，这有助于区分竞争性随机基因表达模型之间的差异。 | Nicoll, A. G. | N/A | Transient power-law behaviour following induction distinguishes between competing models of stochastic gene expression | |
| 在密集混合神经培养物中无偏倚地鉴定细胞身份 | De Beuckeleer, S. | N/A | Unbiased identification of cell identity in dense mixed neural cultures | |
| 通过选择性注意动态调节表征轨迹 | Zhou, Y. | N/A | Dynamic Modulation of Representational Trajectories Through Selective Attention | |
| 有机大分子在输送珍珠层形成所需钙前体的过程中占据了相当大的比例。 | Macias-Sanchez, E. | N/A | Organic macromolecules transport a significant proportion of the calcium precursor for nacre formation. | |
| 基于相关自然统计的高效编码解释的重量错觉 | Bays, P. | N/A | Weight illusions explained by efficient coding based on correlated natural statistics | |
| 鸣禽听觉前脑中用于声音交流信号的预测和错误编码 | Rudraraju, S. | N/A | Predictive and error coding for vocal communication signals in the songbird auditory forebrain | |
| 基因表达在富含调控基序的基因组区域中的出现与演化 | Fuqua, T. | N/A | The emergence and evolution of gene expression in genome regions replete with regulatory motifs | |
| 与阿片类药物使用障碍的大鼠行为模型中的个体差异相关的前额叶皮质中的差异基因表达和染色质可及性 | Liu, S. X. | N/A | Differential gene expression and chromatin accessibility in the medial prefrontal cortex associated with individual differences in rat behavioral models of opioid use disorder | |
| 自闭症相关的PTCHD1错义变异体能与SNARE相关蛋白SNAPIN结合，但表现出细胞内运输障碍。 | Pastore, S. F. | N/A | Autism-associated PTCHD1 missense variants bind to the SNARE-associated protein, SNAPIN, but exhibit impaired subcellular trafficking | |
| 一种用于评估生物化学领域模型分布外表现的新框架 | Fernandez-Diaz, R. | N/A | A new framework for evaluating model out-of-distribution for the biochemical domain | |
| MixtureFinder：用于系统发育分析的DNA混合模型估计 | Ren, H. | N/A | MixtureFinder: Estimating DNA mixture models for phylogenetic analyses | |
| 新兴细菌性植物病原体的多样化；从全球蔓延的穿孔黄单胞菌中获得的见解 | Timilsina, S. | N/A | Diversification of an emerging bacterial plant pathogen; insights from the global spread of Xanthomonas euvesicatoria pv. perforans | |
| 饮食调控背外侧纹状体中的沉默突触 | Meyers, A. M. | N/A | Dietary regulation of silent synapses in the dorsolateral striatum | |
| 解析轴突转录组图谱：从诱导多能干细胞衍生的皮层神经元中获得的见解及其对运动神经元退化的意义 | Xu, J. | N/A | Unraveling Axonal Transcriptional Landscapes: Insights from iPSC-Derived Cortical Neurons and Implications for Motor Neuron Degeneration | |
| BindCompare：一种新颖的蛋白质-核酸结合分析综合平台 | Mahableshwarkar, P. | N/A | BindCompare: A Novel Integrated protein-nucleic Acid Binding Analysis Platform | |
| CCDC113稳定精子轴丝和头尾耦合装置，以确保男性生育能力 | Wu, B. | N/A | CCDC113 stabilizes sperm axoneme and head-tail coupling apparatus to ensure male fertility | |
| 基于定向进化的配体体内再刺激CAR-T细胞的发现 | Grzywa, T. | N/A | Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells | |
| 猕猴V1中上下文调制的依赖性对层间信号流动的影响 | Zhu, S. | N/A | Dependence of Contextual Modulation in Macaque V1 on Interlaminar Signal Flow | |
| 高加索侏儒虾虎鱼（Knipowitschia cf. caucasica）染色体水平基因组参考，这是一种新入侵莱茵河的虾虎鱼科外来物种 | Schoenle, A. | N/A | Chromosome level genome reference of the Caucasian dwarf goby Knipowitschia cf. caucasica, a new alien Gobiidae invadingthe River Rhine | |
| 社会地位对非洲慈鲷后续求偶和交配活动的影响 | Martashvili, A. | N/A | Effects of social position on subsequent courtship and mating activity in an African cichlid | |
| 对500个人类蛋白质域进行定点饱和诱变，揭示了蛋白质失稳对遗传疾病的贡献 | Beltran, T. | N/A | Site saturation mutagenesis of 500 human protein domains reveals the contribution of protein destabilization to genetic disease | |
| 利用贝叶斯参数估计与条件变分自编码器识别肌肉中的机制与治疗靶点 | Tune, T. C. | N/A | Identifying mechanisms and therapeutic targets in muscle using Bayesian parameter estimation with conditional variational autoencoders | |
| 特定的有丝分裂事件驱动细胞骨架重塑，这是左右器官发育所必需的。 | Wu, Y. | N/A | Specific Mitotic Events Drive Cytoskeletal Remodeling Required for Left-Right Organizer Development | |
| 单细胞基因型-表型映射识别VEXAS综合征的治疗脆弱性 | Ganesan, S. | N/A | Single-cell genotype-phenotype mapping identifies therapeutic vulnerabilities in VEXAS syndrome | |
| 瞳孔流形：揭示瞳孔大小相位变化背后的潜在几何结构 | Blini, E. | N/A | Pupillary manifolds: uncovering the latent geometrical structures behind phasic changes in pupil size | |
| 植物质外体中的枯草杆菌蛋白酶SBT5.2能灭活鞭毛蛋白的免疫原性 | Buscaill, P. | N/A | Subtilase SBT5.2 inactivates flagellin immunogenicity in the plant apoplast | |
| 通过活益生菌细菌刺激，对源自健康人结肠类器官的上皮组织和癌细胞系进行全面的基因表达分析 | Sen, A. | N/A | Comprehensive gene expression analysis of organoid-derived healthy human colonic epithelium and cancer cell line by stimulated with live probiotic bacteria | |
| 通过Talin激活β2整合素的分子基础揭示了整合素信号传导的物种特异性机制 | Wu, J. | N/A | Molecular Basis of β2 Integrin Activation by Talin Unveils Species-Specific Mechanisms of Integrin Signaling | |
| 进化视角下的观赏金鱼双尾肌肉纤维分布研究 | Ota, K. | N/A | Evolutionary Insights into Muscle Fiber Distribution in the Twin Tails of Ornamental Goldfish | |
| 视网膜祖细胞中TET家族基因的遗传缺失会损害光感受器发育并导致失明 | Dvoriantchikova, G. | N/A | Genetic ablation of the TET family in retinal progenitor cells impairs photoreceptor development and leads to blindness | |
| 链霉菌天蓝色菌收缩注射系统的功能和激发需要膜蛋白CisA | Casu, B. | N/A | Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA | |
| 小脑作为强化学习机器的尖峰神经网络模型 | Kuriyama, R. | N/A | Spiking network model of the cerebellum as a reinforcement learning machine | |
| 利用Coronin 1作为模板，开发基于肽的融合抑制剂作为抗病毒策略 | Panda, M. S. | N/A | Developing peptide-based fusion inhibitors as an antiviral strategy utilizing Coronin 1 as a template | |
| 传染性喉气管炎病毒基因组编码一种功能性白细胞介素-4同源物：揭示一种新型毒力因子 | Volkening, J. D. | N/A | A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: unveiling a novel virulence factor | |
| 牙源性和牙周膜间充质中NFATc1+/PDGFR-alpha+细胞的包容性、排他性和层级性图谱 | Yang, X. | N/A | Inclusive, Exclusive and Hierarchical Atlas of NFATc1+/PDGFR-alpha+ Cells in Dental and Periodontal Mesenchyme | |
| 疱疹折叠：一种全蛋白质组结构系统方法揭示了所有九种人类疱疹病毒的蛋白质家族和活性 | Soh, T. K. | N/A | HerpesFolds: A proteome-wide structural systems approach reveals insights into protein families and activities of all nine human herpesviruses | |
| 大规模实验量化淀粉样核形成使得蛋白质聚集的深度学习可解释 | Thompson, M. | N/A | Massive experimental quantification of amyloid nucleation allows interpretable deep learning of protein aggregation | |
| 利用基本再生数量化传播并识别野生动物出血热病毒的数据缺口 | Gubbins, S. | N/A | Using the basic reproduction ratio to quantify transmission and identify data gaps for epizootic haemorrhagic disease virus | |
| 用于深入表征纳米颗粒的流式细胞术程序 | Tirelli, V. | N/A | FLOW CYTOMETRIC PROCEDURES FOR DEEP CHARACTERIZATION OF NANOPARTICLES | |
| 在IAA16中插入的可转座元件破坏了剪接过程，导致Bassia scoparia对草甘膦产生抗性。 | Montgomery, J. S. | N/A | A transposable element insertion in IAA16 disrupts splicing and causes dicamba resistance in Bassia scoparia | |
| 多物种全基因组CRISPR筛选鉴定出冷诱导细胞死亡的保守抑制因子 | Lam, B. | N/A | Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death | |
| 单亲和多倍体胚细胞的起源与发展 | Zhao, Y. | N/A | Origin and development of uniparental and polyploid blastomeres | |
| 双工CeTEAM药物生物传感器揭示了PARP抑制剂选择性的决定因素 | Pires, M. J. | N/A | Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity | |
| 多感官诱发电位用于成功分类遗忘型轻度认知障碍的神经机制 | Zhang, L. | N/A | Neural Mechanism Underlying Successful Classification of Amnestic Mild Cognitive Impairment Using Multi-Sensory-Evoked Potentials | |
| 利用病毒RNA基因组中的功能区域作为可药物作用的靶点 | Luo, D. | N/A | Exploiting functional regions in the viral RNA genome as druggable entities | |
| 利用病毒RNA基因组中的功能区域作为可药物作用的靶点 | Luo, D. | N/A | Exploiting functional regions in the viral RNA genome as druggable entities | |
| 在隐球菌中失去RNA干扰后的独特进化轨迹 | Huang, J. | N/A | Distinct evolutionary trajectories following loss of RNA interference in Cryptococcus neoformans | |
| OMG数据集：一个用于混合模态基因组语言建模的开源元基因组语料库 | Cornman, A. | N/A | The OMG dataset: An Open MetaGenomic corpus for mixed-modality genomic language modeling | |
| 光微生境中的互利共生关系推动了拟态蝴蝶群落中的感觉趋同 | Wainwright, J. B. | N/A | Mutualisms within light microhabitats drive sensory convergence in a mimetic butterfly community | |
| 动作意识的神经营机制 | Jin, D. S. | N/A | Neural mechanisms of awareness of action | |
| 一个模块化的免疫反应模型作为计算平台，用于研究感染性疾病的发病机制 | Miroshnichenko, M. | N/A | A modular model of immune response as a computational platform to investigate a pathogenesis of infection disease | |
| GM2神经节苷脂病中的质膜重塑驱动突触功能障碍 | Nicholson, A. S. | N/A | Plasma Membrane Remodelling in GM2 Gangliosidoses Drives Synaptic Dysfunction | |
| DeepPWM-BindingNet：结合序列和PWM特征，释放结合预测能力 | Ali, S. | N/A | DeepPWM-BindingNet: Unleashing Binding Predictionwith Combined Sequence and PWM Features | |
| DNA甲基化保护癌细胞免于衰老。 | Chen, X. | N/A | DNA methylation protects cancer cells against senescence | |
| 甲醇趋化受体MtpA和鞭毛蛋白FliC依赖的甲醇趋化性决定了PPFM在叶际中的时空定殖 | Katayama, S. | N/A | Methanol chemoreceptor MtpA- and flagellin protein FliC-dependent methylotaxis determines the spaciotemporal colonization of PPFM in the phyllosphere | |
| 基因内适应性景观上上位性的变异与可预测性。 | Baheti, S. | N/A | Variations and predictability of epistasis on an intragenic fitness landscape. | |
| 使用脂质锚定控制影响外源货物蛋白与细胞外囊泡结合的物理和生化参数，实现高载量和有效的细胞内递送 | Marquant, A. | N/A | Control of Physical and Biochemical Parameters Influencing Exogeneous Cargo Protein association to Extracellular Vesicle using Lipid Anchors Enables High Loading and Effective Intracellular Delivery | |
| 实体瘤局部给药后肿瘤-CAR T细胞相互作用的时空动力学 | Owens, K. | N/A | Spatiotemporal dynamics of tumor-CAR T-cell interaction following local administration in solid cancers | |
| 棉子糖诱导自噬以促进植物生长 | Magen, S. | N/A | Raffinose induces autophagy to promote plant growth | |
| SMARTER数据库：一种用于整合绵羊和山羊品种SNP阵列数据集的工具 | Cozzi, P. | N/A | SMARTER-database: a tool to integrate SNP arraydatasets for sheep and goat breeds | |
| 牙龈卟啉单胞菌外膜囊泡改变了胚胎小鼠大脑中的神经元结构和Tau磷酸化 | Bradley, A. | N/A | Porphyromonas gingivalis outer membrane vesicles alter neuronal architecture and Tau phosphorylation in the embryonic mouse brain | |
| 蝾螈的表观遗传时钟为揭示极少衰老现象的本质提供了洞见。 | Haluza, Y. | N/A | Axolotl epigenetic clocks offer insights into the nature of negligible senescence | |
| 小脑如何协调运动输出？过去的教训 | Gilbert, M. | N/A | How does the cerebellum coordinate motor outputs? Lessons from the past | |
| 在注意力短暂调节过程中，跨感觉模式的共享皮层下觉醒系统 | Khalaf, A. | N/A | Shared subcortical arousal systems across sensory modalities during transient modulation of attention | |
| 拟南芥在昼夜和发育时间尺度上的稳定和动态基因表达模式 | Redmond, E. J. | N/A | Stable and dynamic gene expression patterns over diurnal and developmental timescales in Arabidopsis thaliana | |
| 基于SENP2的α-突触核蛋白N端截断在路易体病理传播中的作用 | Taguchi, K. | N/A | SENP2-based N-terminal truncation of α-synuclein in Lewy pathology propagation | |
| 基于深度学习的基因扰动效应预测尚未超越简单的线性方法。 | Ahlmann-Eltze, C. | N/A | Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods | |
| 聚焦镓离子束的生物体积电子显微镜依赖于在断面形成辐射抗性富镓层 | Yang, Z. | N/A | Biological volume EM with focused Ga ion beam depends on formation of radiation-resistant Ga-rich layer at block face | |
| 高风险神经精神性拷贝数变异与人类脑细胞中趋同的转录组变化相关 | Dugan, G. | N/A | High-risk neuropsychiatric copy number variants are associated with convergent transcriptomic changes in human brain cells | |
| 基于SATAY的化学基因组筛选揭示了抗真菌抗性机制及ATI-2307和壳聚糖敏感性的关键决定因素 | Karadzas, M. T. | N/A | SATAY-Based Chemogenomic Screening uncovers Antifungal Resistance Mechanisms and Key Determinants of ATI-2307 and Chitosan Sensitivity | |
| 通过使用具有均一N-连接糖基的抗原，利用HDX-MS实现糖蛋白的表位分析 | Ota, T. | N/A | Enabling Epitope Analysis of Glycoproteins via HDX-MS Using Antigens with Uni-formed N-linked Glycans | |
| 持续性的细菌Regiella在鸟樱桃-燕麦蚜虫Rhopalosiphum padi中的转染，增加了宿主的适应性并减少了植物病毒的传播。 | Yu, W. | N/A | A persistent bacterial Regiella transinfection in the bird cherry-oat aphid Rhopalosiphum padi increasing host fitness and decreasing plant virus transmission | |
| 两种特异性纤毛细胞骨架系统在驱动Hedgehog应答转录因子运输中的协同作用 | Ku, P.-i. | N/A | Collaborative role of two distinct cilium-specific cytoskeletal systems in driving Hedgehog-responsive transcription factor trafficking | |
| 慢性淀粉样β寡聚体注射入海马后神经元活动和神经递质释放同时评估的协议 | Herve, V. | N/A | Protocol for simultaneous evaluation of neuronal activity and neurotransmitter release following chronic amyloid-beta oligomer injections into the hippocampus | |
| CLYBL通过修复丙二酰辅酶A，避免了甲基丙二酰辅酶A变位酶的抑制和维生素B12的流失。 | Griffith, C. M. | N/A | CLYBL averts methylmalonyl-CoA mutase inhibition and loss of vitamin B12 by repairing malyl-CoA | |
| 持续注意状态的振荡动力学 | Solis-Vivanco, R. | N/A | Oscillatory dynamics of sustained attention states | |
| 一种用于筛选异构化介导酶药物靶点的差分离子迁移声波喷射质谱系统 | Bazargan, S. | N/A | A Differential Ion Mobility Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets | |
| 区间删失对生物高通量筛选中数据准确性和机器学习性能的影响 | Doffini, V. | N/A | Impact of Interval Censoring on Data Accuracy and Machine Learning Performance in Biological High-Throughput Screening | |
| 脊髓投射的5-羟色胺能神经元对活跃运动状态的增强作用 | Fenstermacher, S. | N/A | Potentiation of active locomotor state by spinal-projecting serotonergic neurons | |
| 利用工程化受体实现合成mRNA的胞外配体响应性翻译调控 | Nakanishi, H. | N/A | Extracellular ligand-responsive translational regulation of synthetic mRNAs using engineered receptors | |
| 斑马鱼Pol-Theta和人Pol-Theta，具有同源功能的直系同源物 | Thomas, C. | N/A | Zebrafish Pol-Theta and Human Pol-Theta, Orthologues with Homologous Function | |
| 鉴定药物/代谢物转运蛋白1作为NF54xCam3.II恶性疟原虫遗传杂交中奎宁耐药性的标志物。 | Kanai, M. | N/A | Identification of the drug/metabolite transporter 1 as a marker of quinine resistance in a NF54xCam3.II P. falciparum genetic cross. | |
| 时间变化刺激延长IKK激活促进核重塑和NF-κB动力学的机制转换 | Smeal, S. W. | N/A | Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics | |
| 分子与神经回路机制：果蝇性经验依赖的长时记忆 | Sun, D. | N/A | Molecular and Neural Circuit Mechanisms Underlying Sexual Experience-dependent Long-Term Memory in Drosophila. | |
| GoldPolish-目标：定向长读长基因组组装抛光 | Zhang, E. | N/A | GoldPolish-Target: Targeted long-read genome assembly polishing | |
| 中缝背核中的血清素能神经元调控视觉注意力 | Lehnert, J. | N/A | Serotonergic neurons in the dorsal raphe regulate visual attention | |
| 概率模型提高了从基因系统发育中进行相对年代测定的效果。 | Bernabeu, M. | N/A | Probabilistic modelling improves relative dating from gene phylogenies | |
| 隐性致病变异携带者的生殖和认知影响 | Fridman, H. | N/A | Reproductive and cognitive effects in carriers of recessive pathogenic variants | |
| 通过结构学习捕捉代理的最佳和次优行为 | Moongathottathil James, A. | N/A | Capturing Optimal and Suboptimal behavior Of Agents Via Structure Learning Of Their Internal Model | |
| 模块化表征在训练用于执行依赖上下文任务的神经网络中出现 | Johnston, W. J. | N/A | Modular representations emerge in neural networks trained to perform context-dependent tasks | |
| 不规律的光照时间表会导致小鼠的日常节律和基因表达发生改变。 | Berbegal-Saez, P. | N/A | Irregular light schedules induce alterations on daily rhythms and gene expression in mice | |
| 邻近蛋白质组学揭示了一个与中心体相关的LRRK2调控网络的共同进化 | Eckert, M. | N/A | Proximity proteomics reveals a co-evolved LRRK2-regulatory network linked to centrosomes | |
| UBE3A的重新激活恢复了印记缺陷的安格曼综合征小鼠模型中的行为和蛋白质组 | Milazzo, C. | N/A | UBE3A reinstatement restores behavior and proteome in an Angelman Syndrome mouse model of Imprinting Defects | |
| 预测误差的层次结构塑造了依赖于情境的感官表征的学习 | Tsai, M. C. | N/A | Hierarchy of prediction errors shapes the learning of context-dependent sensory representations | |
| 用于在体外模拟大脑皮层发育和顺式调控进化的鼠源类器官平台 | Medina-Cano, D. | N/A | A mouse organoid platform for modeling cerebral cortex development and cis-regulatory evolution in vitro | |
| Lgl在有丝分裂退出时重置Par复合物膜加载，以极化神经干细胞 | LaFoya, B. | N/A | Lgl resets Par complex membrane loading at mitotic exit to polarize neural stem cells | |
| 去神经骨骼肌的多模态转录反应涉及胆固醇稳态的改变，影响肌肉大小。 | Calvo, C. | N/A | The multimodal transcriptional response of denervated skeletal muscle involves alterations in cholesterol homeostasis impacting muscle size | |
| 核孔蛋白Nup153将剪接机器锚定在核孔上，以实现高效的mRNA加工。 | De Castro, I. | N/A | Nucleoporin Nup153 docks the splicing machinery to the nuclear pore for efficient mRNA processing | |
| 细胞导航过程中的机械中心体断裂 | Schmitt, M. T. | N/A | Mechanical Centrosome Fracturing during Cell Navigation | |
| 快速无标记活体成像揭示了流体动力学和CD44-HA相互作用在癌细胞滞留于内皮单层中的关键作用 | Follain, G. | N/A | Fast label-free live imaging reveals key roles of flow dynamics and CD44-HA interaction in cancer cell arrest on endothelial monolayers | |
| TET2参与葡萄糖异生并影响2型糖尿病的病理过程。 | Zhang, X. | N/A | TET2 contributes to gluconeogenesis and pathology of type 2 diabetes | |
| 肝窦内皮细胞和层粘连蛋白在慢性肝病中决定胆管细胞的命运 | Manco, R. | N/A | Liver Sinusoidal Endothelial Cells and Laminin dictate cholangiocytes fate in chronic liver disease | |
| 肌动蛋白-肌球蛋白收缩力是人类多能干细胞诱导中胚层形成的有力抑制因素 | Fort, L. | N/A | Actomyosin Contractility is a Potent Suppressor of Mesoderm Induction by Human Pluripotent Stem Cells | |
| 动粒-中心体反馈连接CENP-E和Aurora激酶控制染色体排列 | Vukusic, K. | N/A | Kinetochore-centrosome feedback linking CENP-E and Aurora kinases controls chromosome congression | |
| 去泛素化酶Otub2调节胰腺β细胞功能和存活 | Oshry, M. | N/A | The Deubiquitinating Enzyme Otub2 Modulates Pancreatic Beta-Cells Function and Survival | |
| 肌联蛋白依赖的生物力学反馈使昆虫的肌节适应其特殊的肌肉功能 | Loreau, V. | N/A | Titin-dependent biomechanical feedback tailors sarcomeres to specialised muscle functions in insects | |
| 在海鞘Ciona中，特异性于被囊动物的蛋白质Epi-1对于赋予幼虫被囊亲水性是必不可少的。 | Kuroiwa, K. | N/A | Tunicate-specific protein Epi-1 is essential for conferring hydrophilicity to the larval tunic in the ascidian Ciona | |
| 极体在蜘蛛前后轴形成过程中起到地标作用 | Wang, R. | N/A | Polar bodies serve as a landmark for anteroposterior axis formation in spiders | |
| 分支肌动蛋白聚合驱动侵入性突起的形成，以促进骨骼肌再生过程中肌纤维母细胞的融合。 | Lu, Y. | N/A | Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration | |
| 早期合子工程促进靶向性大型转基因整合及全转基因动物的直接生产 | Gupta, K. | N/A | Early zygotic engineering promotes targeted large transgene integration and direct production of fully transgenic animals | |
| 母体高脂高蔗糖饮食引起的过度肥胖与妊娠晚期胎盘缺氧及胎盘免疫稳态紊乱有关。 | Bellissimo, C. J. | N/A | Maternal high-fat, high-sucrose diet-induced excess adiposity is linked to placental hypoxia and disruption of fetoplacental immune homeostasis in late gestation | |
| RO8191是一种用于在小鼠中启动胚胎植入的新化合物。 | Shu, J. | N/A | RO8191, a new compound for initiating embryoimplantation in mice | |
| 胞质增强型基于暗Epac的FRET传感器用于通过FLIM在活细胞中检测细胞内cAMP | Zanetti, G. | N/A | Cytosolic Enhanced Dark Epac-Based FRET Sensors for Intracellular cAMP detection in live cells via FLIM | |
| SC-MAMBA2：利用状态空间模型实现高效单细胞超长转录组建模 | Zhao, Y. | N/A | SC-MAMBA2: Leveraging State-Space Models for Efficient Single-Cell Ultra-Long Transcriptome Modeling | |
| 菊芋提取物调节脂肪酸生物合成中关键酶的基因表达 | Bunch, H. | N/A | Jerusalem artichoke extracts regulate the gene expression of key enzymes involved in fatty acid biosynthesis | |
| 低表达的NOTCH1改变了左心发育不良综合征中心肌细胞的细胞结构 | Lewis, J. | N/A | Hypomorphic NOTCH1 Expression Alters Cardiomyocyte Cellular Architecture in Hypoplastic Left Heart Syndrome | |
| 钙稳态调节剂2在线粒体中构成一个ATP调控孔 | GUO, Q. | N/A | Calcium Homeostasis Modulator 2 Constitutes an ATP-regulation Pore in Mitochondria | |
| S1PR1调节淋巴管瓣膜发育并防止非肠炎依赖的淋巴样器官形成 | Geng, X. | N/A | S1PR1 Regulates Lymphatic Valve Development And Prevents Ileitis-Independent Tertiary Lymphoid Organ Formation | |
| 在拟南芥中，PRESSED FLOWER 通过下游作用于 ASYMMETRIC LEAVES 2 来影响萼片的扁平度。 | Liu, R. | N/A | PRESSED FLOWER works downstream of ASYMMETRIC LEAVES 2 to affect sepal flatness in Arabidopsis | |
| 量化生化途径中的癌症药物靶向性 | Hagler, S. | N/A | Quantifying Cancer Drug Targetability across Biochemical Pathways | |
| 细菌中脉冲基础基因表达作为适应性决定因素 | Jain, K. | N/A | Pulsatile basal gene expression as a fitness determinant in bacteria | |
| 可解释人工智能在MRI分析中的应用：将模型预测与老化大脑的神经影像特征相关联 | Hofmann, S. M. | N/A | The utility of explainable A.I. for MRI analysis: Relating model predictions to neuroimaging features of the aging brain | |
| 对具有广谱抗病毒能力的木薯（Manihot esculenta）品系COL40进行单倍体型解析组装，揭示了位于12号染色体上含有大量重复元件的区域，这些病毒是导致木薯褐条病的原因。 | Thoben, C. | N/A | The haplotype-resolved assembly of COL40 a cassava (Manihot esculenta) line with broad-spectrum resistance against viruses causing Cassava brown streak disease unveils a region of highly repeated elements on chromosome 12 | |
| 使用张量分解的AI驱动计算方法可以在整合多个Hi-C数据集时发现共同的优化bin大小。 | Taguchi, Y.-h. | N/A | Novel AI-powered computational method using tensor decomposition can discover the common optimal bin sizes when integrating multiple Hi-C datasets | |
| 基于mRNA的RSV preF疫苗在临床前研究中的疗效和安全性 | bai, h. | N/A | Efficacy and safety of an mRNA-based RSV preF vaccine in preclinical studies | |
| 温带森林林下草本植物和禾草类植物对干旱胁迫的形态和生理反应比较 | Petek-Petrik, A. | N/A | Comparison of morphological and physiological response to drought stress among temperate forest understory forbs and graminoids | |
| IQD2招募KLCR1到膜-微管连接处，促进叶表皮铺路细胞的细胞骨架力学响应性 | Buhl, J. | N/A | IQD2 recruits KLCR1 to the membrane-microtubule nexus to promote cytoskeletal mechano-responsiveness in leaf epidermis pavement cells | |
| 植物免疫受体广谱识别病原效应蛋白的定向进化 | Rim, E. Y. | N/A | Directed evolution of a plant immune receptor for broad spectrum recognition of pathogen effectors | |
| 墨西哥酸橙基因组二倍体组装揭示了广泛的杂合性 | Leichty, A. | N/A | Diploid assembly of the Mexican lime genome reveals extensive heterozygosity | |
| 叶片气腔中的不饱和与近似同位素均质性 | Collaviti, S. E. | N/A | Unsaturation and Approximate Isotopic Homogeneity in Leaf Air Spaces | |
| 自闭症患者在观察触摸时的动态功能适应：连接强度与对社交触摸的态度和社会反应性有关 | Masson, H. L. | N/A | Dynamic functional adaptations during touch observation in autism: Connectivity strength is linked to attitudes towards social touch and social responsiveness | |
| 多种转录因子调控阿氏肠杆菌中易错DNA聚合酶基因的表达 | Nguyen, B. H. | N/A | Multiple transcription factors regulate the expression of genes for error prone DNA polymerases in Acinetobacter baumannii | |
| 群体感应和DNA甲基化在临床伯克霍尔德菌的相变中起着积极作用。 | Coulon, P. M. L. . | N/A | Quorum sensing and DNA methylation play active roles in clinical Burkholderia phase variation | |
| 双单倍体溪红点鲑（Salvelinus fontinalis）的染色体水平基因组组装 | Lecomte, L. | N/A | Chromosome-level genome assembly of a doubled haploid brook trout (Salvelinus fontinalis) | |
| 一种用于缓解晕车的可穿戴正念脑机接口 | Zhu, J. | N/A | A Wearable Mindfulness Brain-Computer Interface for Alleviating Car Sickness | |
| 针对嗅觉受体可通过肌动蛋白细胞骨架解聚减轻高残余血小板反应性和动脉血栓形成 | Aggarwal, A. | N/A | Targeting an Olfactory Receptor Mitigates High Residual Platelet Reactivity and Arterial Thrombosis Through Actin Cytoskeleton Depolymerization | |
| 特定种子特异性过表达改良的小麦Or基因可提高水稻和小麦籽粒中的β-胡萝卜素含量。 | Sirohi, P. | N/A | Seed specific overexpression of a modified wheat Or gene leads to enhanced β-carotene in rice and wheat grains | |
| 数据猎人：连接生物信息学教育和微生物组研究 | Fumagalli, S. | N/A | Data Hunters: bridging bioinformatics education and microbiome research | |
| 通过完全自主的HABITS系统实现新颖且优化的鼠标行为：家庭笼辅助行为创新与测试系统 | Yu, B. | N/A | Novel and optimized mouse behavior enabled by fully autonomous HABITS: Home-cage Assisted Behavioral Innovation and Testing System | |
| 一个模仿大肠杆菌膜生物物理特性的极简模型脂质系统 | Tormena, N. | N/A | A minimalist model lipid system mimicking the biophysical properties of Escherichia coli membrane | |
| R405W desmin敲入小鼠的综合数据显示，肌纤维病初期阶段线粒体功能、蛋白质质量控制和肌纤维结构的改变。 | Batonnet-Pichon, S. | N/A | Integrated data from R405W desmin knock-in mice highlight alterations of mitochondrial function, protein quality control, and myofibrillar structure in the initial stages of myofibrillar myopathy | |
| 宿主树木叶片对昆虫病原体多态性的影响 | Freedman, A. S. | N/A | Effects of Host-Tree Foliage on Polymorphism in an Insect Pathogen | |
| 宿主树木叶片对昆虫病原体多态性的影响 | Freedman, A. S. | N/A | Effects of Host-Tree Foliage on Polymorphism in an Insect Pathogen | |
| 流体流动影响血管炎症纤维化模型中的内皮细胞-单核细胞相互作用 | Linares, I. | N/A | Fluid Flow Impacts Endothelial-Monocyte Interactions in a Model of Vascular Inflammatory Fibrosis | |
| STIX：基于长读长测序的群体规模结构变异精准注释 | Zheng, X. | N/A | STIX: Long-reads based Accurate Structural Variation Annotation at Population Scale | |
| 以患者为中心的知识图谱方法，用于优先筛选突变体以进行选择性抗癌靶向治疗 | Gorostiola Gonzalez, M. | N/A | A patient-centric knowledge graph approach to prioritize mutants for selective anti-cancer targeting | |
| 负责胸腺功能的基本相互作用解释了复杂的髓质形状 | Muramatsu, D. | N/A | Basic interactions responsible for thymus function explain convoluted medulla shape | |
| 从遗传学定义的小鼠肝母细胞瘤中高效衍生出永生化、同基因细胞系 | Wang, H. | N/A | Efficient Derivation of Immortalized, Isogenic Cell Lines from Genetically Defined Murine Hepatoblastomas | |
| 早期青少年期第二代抗精神病药物暴露对体重、热量摄入及代谢相关基因表达的长期影响 | Soto, P. | N/A | Long-Term Effects of Early Adolescent Second-Generation Antipsychotic Exposure on Body Weight, Caloric Intake, and Metabolism-Associated Gene Expression | |
| 吞噬作用通过PGE2的形成和EP4信号在M1型和M2型巨噬细胞中受到LPS的不同调控。 | Kirchhoff, R. | N/A | Phagocytosis is differentially regulated by LPS in M1- and M2-like macrophages via PGE2 formation and EP4 signaling | |
| 印度东部喜马拉雅季节性热带森林中的叶、花和果实物候模式及其与环境的关系 | Datta, A. | N/A | Patterns of leaf, flower and fruit phenology and environmental relationships in a seasonal tropical forest in the Indian Eastern Himalaya | |
| 药用植物对南方根结线虫（Meloidogyne javanica）的植物化学分析和杀线虫活性研究 | Maher, S. | N/A | Phytochemical Analysis and Nematicidal Activity of Medicinal Plants Against Meloidogyne javanica | |
| 配体结合对人类内皮细胞中VEGFR1、VEGFR2和NRP1定位的影响 | Sarabipour, S. | N/A | Impact of ligand binding on VEGFR1, VEGFR2, and NRP1 localization in human endothelial cells | |
| 成年雄性大鼠扣带区（下边缘区和前扣带区，背侧部分）与间脑（间脑）之间的双向连接的地形组织 | Negishi, K. | N/A | Topographic organization of bidirectional connections between the cingulate region (infralimbic area and anterior cingulate area, dorsal part) and the interbrain (diencephalon) of the adult male rat | |
| 环境无关物体识别的硬连线视觉滤波器 | Kang, M. | N/A | Hard-wired visual filters for environment-agnostic object recognition | |
| 生理因素对静息态和任务态功能连接影响的调查 | Askarinejad, S. E. | N/A | Investigation of the effect of physiological factors on resting-state and task-based functional connectivity | |
| 淀粉样β病理加速了5xFAD小鼠视觉通路的改变 | McCool, S. | N/A | Amyloid Beta Pathology Accelerates Alterations in the Visual Pathway of the 5xFAD Mouse | |
| 复杂运动轨迹由蝗虫中多个运动敏感的下行中间神经元的总体活动所形成的人口编码来表示。 | Zhang, S. | N/A | Complex motion trajectories are represented by a population code from the ensemble activity of multiple motion-sensitive descending interneurons in locusts | |
| 使用鼠尾草酸治疗可减轻IL-33激活后促炎性肥大细胞介质的分泌 | Crozier, R. W. E. | N/A | Treatment with carnosic acid attenuates the secretion of pro-inflammatory mast cell mediators following IL-33 activation | |
| 在赫拉克勒斯蚁中，节俭的超个体表型作为一种可塑性反应，出现在极端环境中。 | Plante, E. | N/A | Thrifty superorganism phenotypes emerge as a plastic response to extreme environments in the Hercules ant | |
| 珊瑚礁修复的人口基因组学——密克罗尼西亚鹿角珊瑚的案例研究 | Rios, D. | N/A | Population genomics for coral reef restoration - a case study of staghorn corals in Micronesia | |
| 加拉帕戈斯群岛Scalesia适应性辐射中的基因组稳定性：尽管存在杂交和生态位转变，转座元件的积累依然一致 | Cerca, J. | N/A | Genomic stability in the Galapagos Scalesia adaptive radiation: Consistent transposable element accumulation despite hybridization and ecological niche shifts | |
| 在果蝇中，心脏性能的衰老自然变化揭示了PAR域bZIP转录因子Pdp1/dHLF在心脏衰老中的核心功能 | Audouin, K. | N/A | Natural variations of aging of cardiac performance in Drosophila identifies a central function for the PAR domain bZIP transcription factor Pdp1/dHLF in cardiac senescence | |
| 巨大的染色体外元素“Inocle”可能潜在地扩展了人类口腔微生物群的适应能力 | Kiguchi, Y. | N/A | Giant extrachromosomal element "Inocle" potentially expands the adaptive capacity of the human oral microbiome | |
| GeTMoR：同时进行基因组、转录组和形态学的稀有单细胞分析 | Prabakar, R. K. | N/A | GeTMoR: Simultaneous genomic, transcriptomic, andmorphological profiling of rare single cells | |
| 在小鼠中对可口糖的暴饮暴食进行情境增强 | Matsui, H. | N/A | Contextual enhancement on binge-like overconsumption of palatable sugar in mice | |
| 迭代牺牲三维打印与聚合物铸造技术用于制造复杂血管移植物及多腔室生物人工器官 | Brassard, J. A. | N/A | Iterative sacrificial 3D printing and polymer casting to create complex vascular grafts and multi-compartment bioartificial organs | |
| 电阻抗光谱作为一种检测前列腺癌细胞上皮间质转化的工具 | Crowell, L. L. | N/A | Electrical Impedance Spectroscopy as a Tool to Detect the Epithelial to Mesenchymal Transition in Prostate Cancer Cells | |
| 一种新型工程化U7小核RNA支架在体外和体内显著增加了ADAR介导的可编程RNA碱基编辑 | Byrne, S. M. | N/A | A Novel Engineered U7 Small Nuclear RNA Scaffold Greatly Increases in vitro and in vivo ADAR-Mediated Programmable RNA Base Editing | |
| 一种新型工程化U7小核RNA支架在体外和体内显著增强了ADAR介导的可编程RNA碱基编辑 | Byrne, S. M. | N/A | A Novel Engineered U7 Small Nuclear RNA Scaffold Greatly Increases in vitro and in vivo ADAR-Mediated Programmable RNA Base Editing | |
| PlasmidGPT：一个用于质粒设计和注释的生成框架 | SHAO, B. | N/A | PlasmidGPT: a generative framework for plasmid design and annotation | |
| 公民科学家在远足期间未检测到的现象，可以建模为天气、季节、清单长度和个人偏好的函数。 | Jacobusse, G. W. | N/A | Non-detection during excursions by citizen scientists modeled as a function of weather, season, list length, and individual preferences | |
| 解锁低质量总RNA-seq数据的潜力：一种逐步映射方法以改进定量分析 | Lee, J. | N/A | Unlocking the Potential of Low Quality Total RNA-seq Data: A Stepwise Mapping Approach for Improved Quantitative Analyses | |
| Eps15 EH结构域与内在无序蛋白质之间的竞争性相互作用形成了一个复杂的相互作用网络。 | Papagiannoula, A. | N/A | Competitive interactions between Eps15 EH domains and intrinsically disordered proteins generate a complex interaction network | |
| 弹簧加载的DNA折纸阵列作为模块化纳米机器人的能量供应硬件 | Pfeiffer, M. | N/A | Spring-loaded DNA origami arrays as energy-supplied hardware for modular nanorobots | |
| 非整倍体上位性图谱揭示了与癌症中多余染色体相关的代谢脆弱性 | Magesh, R. Y. | N/A | An aneuploidy epistasis map reveals metabolic vulnerabilities associated with supernumerary chromosomes in cancer | |
| 基于深度学习的母体心电图推断子宫收缩 | Tanaka, S. | N/A | Deep Learning-Based Inference of Uterine Contractions from Maternal ECG | |
| BMP信号调节控制原条的形成 | Simon, G. | N/A | BMP signaling modulations control primitive streak patterning | |
| 鸣禽红眉金丝雀（Neochmia temporalis temporalis）中非典型精子形态的独立进化 | Rowe, M. | N/A | Independent evolution of atypical sperm morphology in a passerine bird, the red-browed finch (Neochmia temporalis temporalis) | |
| 在平均任务中，观察结果的不精确计数预测了首因效应和近因效应 | Prat-Carrabin, A. | N/A | Imprecise counting of observations in averaging tasks predicts primacy and recency effects | |
| 探索无偿献血者中红细胞参数与血小板指数之间的关联 | De, R. | N/A | Exploring the link between extended red blood cell parameters and platelet indices in voluntary blood donors | |
| 层粘连蛋白调控核力学与形态，以控制胶质母细胞瘤细胞的增殖、迁移和侵袭。 | Wang, X. | N/A | Lamins regulate nuclear mechanics and shape to control glioblastoma cell proliferation, migration and invasion | |
| 多模态大语言模型实现药物机制和性质的全方位预测 | Liang, Y. | N/A | Multi-Modal Large Language Model Enables All-Purpose Prediction of Drug Mechanisms and Properties | |
| 首次完成昆虫眼睛的三维重建与形态功能图谱绘制 | Makarova, A. A. | N/A | The first complete 3D reconstruction and morphofunctional mapping of an insect eye | |
| 电磁刺激微丝化水凝胶用于引导神经元形态发生 | Jensen, B. N. | N/A | Electromagnetic Stimulated Microfillamented Hydrogels for Guided Neuronal Morphogenesis | |
| 通过将EM算法应用于改进的广义线性模型，将生物学变异与噪声分离 | Lee, T.-W. | N/A | Separating biological variance from noise by applying EM algorithm to modified General Linear Model | |
| 利用bond-boost超动力学方法研究蛋白质路径的加速分子动力学研究 | Park, S. W. | N/A | An accelerated molecular dynamics study for investigating protein pathways using the bond-boost hyperdynamics method | |
| 巨核细胞构建了一个细胞外基质笼，控制其成熟和锚定于血管壁龛。 | Masson, C. | N/A | Megakaryocytes build a cage of extracellular matrix that controls their maturation and anchoring to the vascular niche | |
| 维持神经元中TDP-43的表达需要轴突溶酶体的运输 | Ryan, V. H. | N/A | Maintenance of neuronal TDP-43 expression requires axonal lysosome transport | |
| 调节秀丽隐杆线虫进入持久化状态决策的神经元活动 | Prakash, S. J. | N/A | Neuronal activity regulating the dauer entry decision in Caenorhabditis elegans | |
| 在实时fMRI神经反馈中引入触觉反馈：一种调节初级运动皮层活动的新方法 | Fleury, M. | N/A | Introducing Haptic Feedback in Real-Time fMRI Neurofeedback: A Novel Approach to Modulate Primary Motor Cortex Activity | |
| 鉴定与中国仓鼠卵巢（CHO）细胞适应性相关的细胞特征，以分泌抗体 | Bai, Y. | N/A | Identification of Cellular Signatures Associated with Chinese Hamster Ovary (CHO) Cell Adaptation for Secretion of Antibodies | |
| UniGEN-DDI：利用统一图嵌入网络计算药物-药物相互作用 | Mondal, S. | N/A | UniGEN-DDI: Computing drug-drug interactions using a unified graph embedding network | |
| 人类Toll样受体中的亮氨酸重复结构域中个体差异的重复出现解释了它们的多样性和功能适应性。 | Takkouche, A. | N/A | Divergence of the Individual repeats in the leucine-rich repeat domains of human Toll-like receptors explain their diversity and functional adaptations. | |
| RAPDOR：利用Jensen-Shannon距离进行复杂蛋白质组学数据集的计算分析 | Hemm, L. | N/A | RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets | |
| 武士：使用可重复且集成的生物信息学管道对拷贝数变异进行浅层分析 | Potente, S. | N/A | SAMURAI: Shallow Analysis of Copy nuMber alterations Using a Reproducible And Integrated bioinformatics pipeline | |
| 捕捉哺乳动物细胞的层次分类蛋白质相互作用模块 | Dai, S. | N/A | Capturing the Hierarchically Assorted Protein-protein Interaction Modules of Mammalian Cell | |
| 锌离子介导的胱天蛋白酶-3非竞争性抑制的计算分析 | Tian, X. E. | N/A | Computational Analysis of Zn2+ Mediated Non-Competitive Inhibition to Caspase-3 | |
| GPCR结构域与功能的关系：受体螺旋束和C端对GRK特异性功能和β-arrestin介导的调控有不同的影响 | Matthees, E. S. | N/A | Relating GPCR domains with functionality: receptor helix-bundle and C-terminus differentially influence GRK-specific functions and β-arrestin-mediated regulation | |
| 基准测试用于后扰动RNAseq预测的基础细胞模型 | Csendes, G. | N/A | Benchmarking a foundational cell model for post-perturbation RNAseq prediction | |
| 溶质载体超家族互作网络 | Frommelt, F. | N/A | The solute carrier superfamily interactome | |
| VPS35(D620N)敲入小鼠中出现的谷氨酸和多巴胺功能障碍及LRRK2抑制剂的快速逆转 | Kamesh, A. | N/A | Emergent glutamate & dopamine dysfunction in VPS35(D620N) knock-in mice and rapid reversal by LRRK2 inhibition | |
| 心理努力和反事实情境对语言理解的影响：老年人ERP证据 | Salas-Herrera, J. L. | N/A | Mental Effort and Counterfactuals Modulate Language Understanding: ERP Evidence in Older Adults | |
| 一种无需使用仿真体即可实现PET图像空间分辨率校正的新方法 | Carbonell, F. | N/A | A novel method for harmonization of PET image spatial resolution without phantoms | |
| 将显微镜与扩散磁共振成像通过退化的生物物理模型相连接：贝叶斯变化估计（BENCH）框架的应用 | Kor, D. Z. L. | N/A | Linking microscopy to diffusion MRI with degenerate biophysical models: an application of the Bayesian EstimatioN of CHange (BENCH) framework | |
| tau病变的分类揭示了原丝核心残基的作用。 | Vaquer-Alicea, J. | N/A | Functional classification of tauopathy strains reveals the role of protofilament core residues. | |
| 奇怪的异常反应反映了小鼠初级视觉皮层中复杂且依赖于情境的预期 | Knudstrup, S. G. | N/A | Oddball evoked deviant responses reflect complex context dependent expectations in mouse V1 | |
| CXXC指蛋白1与FOXP3相互作用，以稳定调节性T细胞的稳态和抑制功能 | Meng, X. | N/A | CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells | |
| 改变游戏规则的突变 | Edhan, O. | N/A | Game Changing Mutation | |
| 甲基组揭示了两种植物物种群体中最近的进化变化 | Korfmann, K. | N/A | Methylomes reveal recent evolutionary changes in populations of two plant species | |
| 脂肪组织中瘦素上游增强子表观遗传修饰的性别特异性作用 | Mueller, L. | N/A | Sex-specific role of epigenetic modification of a leptin upstream enhancer in the adipose tissue | |
| 基因组关联研究的谱系蒸馏 | Christ, R. | N/A | Clade Distillation for Genome-wide Association Studies | |
| 现场采集的蜱虫中存在Powassan病毒缺失和缺陷RNA的证据 | Langsjoen, R. M. | N/A | Evidence for Powassan virus deletions and defective RNA in field collected ticks | |
| 通过动态结构学习推断代理的时间变化内部模型 | Moongathottathil James, A. | N/A | Inferring Time-Varying Internal Models of Agents Through Dynamic Structure Learning | |
| 同位素标记在MaxQuant中的更新 | Ferretti, D. | N/A | Isobaric labeling update in MaxQuant | |
| 在成像质谱数据降维中保留全光谱信息 | Moens, R. A. R. | N/A | Preserving Full Spectrum Information in ImagingMass Spectrometry Data Reduction | |
| BindCraft：功能性蛋白质结合剂的一步设计 | Pacesa, M. | N/A | BindCraft: one-shot design of functional protein binders | |
| 瞬时蛋白质结构指导膜超复合物中电子传递的表面扩散路径 | Chan, C. K. | N/A | Transient protein structure guides surface diffusion pathways for electron transport in membrane supercomplexes | |
| 在唐氏综合症B细胞急性淋巴母细胞白血病中，可以通过使用Venetoclax靶向代谢脆弱性。 | Jones, D. | N/A | Metabolic vulnerabilities in Down syndrome B-cell acute lymphoblastic leukemia can be targeted using Venetoclax | |
| 脑转移中三级淋巴结构的鉴定与特征分析 | Mughal, S. S. | N/A | Identification and characterization of tertiary lymphoid structures in brain metastases | |
| 使用性别特异性的心脏模拟器实时预测药物引起的致心律失常风险 | Dominguez-Gomez, P. | N/A | Real-time prediction of drug-induced proarrhythmic risk with sex-specific cardiac emulators | |
| 草酸钙结石形成者的酸排泄受损 | Silva, P. H. I. | N/A | Acid excretion is impaired in calcium oxalate stone formers | |
| 陆地植物免疫稳态模块的保守性 | Dou, R. | N/A | Conservation of an immune homeostasis module in land plants | |
| 小型化实验室设备作为在基础设施有限的西非国家实施保护遗传学工具和教育的解决方案：以几内亚比绍非法野生动物贸易研究为例 | da Silva, M. J. F. | N/A | Miniaturised laboratorial equipment as a solution to implement conservation genetics tools and education in West African countries with limited infrastructures: an application to the study of illegal wildlife trade in Guinea-Bissau | |
| 9.4 T下人脑中代谢物和大分子的定量二维J分辨代谢物循环半LASER光谱学 | Murali-Manohar, S. | N/A | Quantitative 2D J-resolved metabolite-cycled semiLASER spectroscopy of metabolites and macromolecules in the human brain at 9.4 T | |
| 基于生物学的芯片上脑模型识别出在高度兴奋的神经网络中选择性的地形重组 | Poinsot, M. | N/A | Biologically grounded brain-on-chip model identifies selective topographic reorganization within hyperexcitable neural networks | |
| 多巴胺活动在条件性味觉厌恶范式中编码同一刺激的情感变化 | Loh, M. | N/A | Dopamine activity encodes the changing valence of the same stimulus in conditioned taste aversion paradigms | |
| 亲社会行为的可分离后效：努力对他人的代价高，但对自己有价值 | Zheng, Y. | N/A | Dissociable after-effects of prosocial acts: Effort is costly for others but valued for self | |
| 独特的表达谱揭示了三叉神经系统中胶质细胞的参与，这与创伤后头痛有关。 | Nagarajan, G. | N/A | Distinct expression profile reveals glia involvement in the trigeminal system attributing to post-traumatic headache | |
| 传粉者是否在塑造花蜜中必需氨基酸方面发挥作用？ | Parkinson, R. H. | N/A | Do pollinators play a role in shaping the essential amino acids found in nectar? | |
| 检测金黄色葡萄球菌核心基因组中推动抗生素抗性的正向选择 | Rimmer, C. O. | N/A | Detection of positive selection driving antimicrobial resistance in the core genome of Staphylococcus epidermidis | |
| 具备开发人类基因组标准E701的经验 | Vasiliadis, I. | N/A | Experience in developing the human genome standard E701 | |
| scGNN+：将ChatGPT适配于无缝教程与代码优化 | Jiang, Y. | N/A | scGNN+: Adapting ChatGPT for Seamless Tutorial and Code Optimization | |
| 小鼠前列腺腺体中的核苷酸酶和嘌呤能受体 | Yu, J. | N/A | Ectonucleotidases and Purinergic Receptors in Mouse Prostate Gland | |
| CalTrig：一种基于图形用户界面的机器学习方法，用于解码自由活动啮齿动物中的神经元钙瞬变 | Lange, M. A. | N/A | CalTrig: A GUI-Based Machine Learning Approach for Decoding Neuronal Calcium Transients in Freely Moving Rodents | |
| 通过罗望子果实乙醇提取物改善氟化钠处理的大鼠氧化应激 | Usman, L. A. | N/A | Amelioration of Oxidative Stress in Sodium Fluoride-administered Wistar Rats by Tamarindus indica Fruit Pulp Ethanolic Extract | |
| 利用分子模拟和机器学习辅助的CDR移植技术设计靶向SARS-CoV-2刺突糖蛋白的纳米抗体 | Ferraz, M. V. F. | N/A | Design of nanobody targeting SARS-CoV-2 spike glycoprotein using CDR-grafting assisted by molecular simulation and machine learning | |
| 多样化的、微型化的和祖先的部件用于哺乳动物基因组工程和分子记录 | McDiarmid, T. A. | N/A | Diversified, miniaturized and ancestral parts for mammalian genome engineering and molecular recording | |
| Cxcl10在小鼠SARS-CoV-2感染期间对生存至关重要 | Majumdar, S. | N/A | Cxcl10 is required for survival during SARS-CoV-2 infection in mice | |
| 一个独特的细菌家族再次出击！ | Shukla, G. | N/A | A unique bacterial family strikes again! | |
| 隐孢子虫微粒体中替代性电子传递链的功能 | Deng, S. | N/A | Function of the alternative electron transport chain in the Cryptosporidium parvum mitosome | |
| MutRS群体感应系统控制人类病原体变异链球菌中的细菌素变菌素生产。 | Wyllie, R. M. | N/A | The MutRS quorum sensing system controls lantibiotic mutacin production in the human pathogen Streptococcus mutans | |
| 克鲁兹锥虫细胞图谱；理解寄生虫种群异质性和分化的单细胞资源。 | Laidlaw, R. | N/A | The Trypanosoma cruzi cell atlas; a single-cell resource for understanding parasite population heterogeneity and differentiation. | |
| 临床收集的细菌性阴道病诊断样本中阴道微生物群的特征分析 | Brochu, H. N. | N/A | Characterization of vaginal microbiomes in clinician-collected bacterial vaginosis diagnosed samples | |
| 从rocaglates/aglains库筛选中体外发现手足口病的治疗先导 | Oo, A. | N/A | In vitro discovery of a therapeutic lead for HFMD from a library screen of rocaglates/aglains | |
| PfPPM2信号传导调控人类疟原虫恶性疟原虫的无性分裂和有性转换 | Rawat, A. | N/A | PfPPM2 signalling regulates asexual division and sexual conversion of human malaria parasite Plasmodium falciparum | |
| B组链球菌通过裂解内皮细胞感染大脑，在斑马鱼脑膜炎模型中 | Ravishankar, S. | N/A | Group B streptococci lyse endothelial cells to infect the brain in a zebrafish meningitis model | |
| 替考拉宁在体外可减轻RNA病毒感染 | Espano, E. | N/A | Teicoplanin attenuates RNA virus infection in vitro | |
| 依赖于Rho的终止和RNase E介导的切割：多顺反子mRNA 3'端加工的双重途径 | Jeon, H. J. | N/A | Rho-dependent termination and RNase E-mediated cleavage: Dual pathways for RNA 3' end processing in polycistronic mRNA | |
| 一种新型重组聚羟基丁酸（PHB）生产平台，在丝状蓝藻中避免氮饥饿的同时保持细胞活力 | Fink, P. | N/A | A novel recombinant PHB production platform in filamentous cyanobacteria avoiding nitrogen starvation while preserving cell viability | |
| 骨细胞树突中mRNA的转运与翻译 | Mazur, C. M. | N/A | Trafficking and translation of mRNA in osteocyte dendrites | |
| 晚年短期饮食限制改善了肠道干细胞功能，并影响了肠道干细胞的DNA甲基化。 | Kurup, K. | N/A | Late-life short-term dietary restriction ameliorates intestinal stem cell function and impacts intestinal stem cell DNA methylation | |
| 可扩展制造用于自动化室温X射线蛋白质晶体学的阵列型固定靶装置 | Saha, S. | N/A | Scalable Fabrication of an Array-Type Fixed-Target Device for Automated Room Temperature X-ray Protein Crystallography | |
| 长角甲虫利用磷酸钙生物矿物形成结构色 | Chang, Y. | N/A | Longhorn Beetles form Structural Colour Using Calcium Phosphate Biominerals | |
| 利用计算机模拟和表征爱泼斯坦-巴尔病毒的LMP1蛋白 | Abdul Salam, D. S. | N/A | In silico modelling and characterization of Epstein Barr virus LMP1 protein | |
| HRS的二维凝聚体驱动扁平网格蛋白笼在内涵体上的组装 | Hakala, M. | N/A | Two-dimensional condensates of HRS drive the assembly of flat clathrin lattices on endosomes | |
| 开发高效且选择性的CK1α分子胶降解剂 | Geng, Q. | N/A | Development of potent and selective CK1α Molecular Glue Degraders | |
| 计算人类相互作用组 | Zhang, J. | N/A | Computing the Human Interactome | |
| 塑造哺乳动物PRPS酶复合体的进化起源与创新 | Karki, B. | N/A | Evolutionary origins and innovations sculpting the mammalian PRPS enzyme complex | |
| 一种具有共同参考框架的分子表示系统，用于天然产物途径发现和结构多样性任务。 | Babineau, N. | N/A | A molecular representation system with a common reference frame for natural products pathway discovery and structural diversity tasks. | |
| 新世界哺乳动物沙粒病毒刺突复合物抗原糖蛋白构建块的结构与稳定化 | Paesen, G. C. | N/A | Structure and stabilization of the antigenic glycoprotein building blocks of the New World mammarenavirus spike complex | |
| c-di-GMP效应蛋白FleQ通过抑制Azotobacter vinelandii中algD基因的转录来控制海藻酸盐的产生。 | BARRIOS-RAFAEL, V. V. | N/A | The c-di-GMP effector FleQ controls alginate production by repressing transcription of the algD gene in Azotobacter vinelandii | |
| 肺炎球菌素B是一种链球菌素B，作为早期感受态级联反应的一部分产生，并促进种内竞争。 | Richardson, J. D. | N/A | The pneumococcal bacteriocin streptococcin B is produced as part of the early competence cascade and promotes intraspecies competition. | |
| 来自阴沟肠杆菌的一种岩藻糖结合超凝集素，具有高度的Lewis和ABO血型抗原特异性。 | Beshr, G. | N/A | A fucose-binding superlectin from Enterobacter cloacae with high Lewis and ABO blood group antigen specificity | |
| 多组学分析揭示了BnC07MYB3a在甘蓝型油菜种皮颜色中的作用机制。 | Hu, R. | N/A | Multi-omics analysis reveals the mechanism of BnC07MYB3a is involved in seed coat color in Brassica napus L. | |
| CK1α、FAM83H和FAM83B参与神经丝的捆绑，并在ARSACS的细胞和小鼠模型中被隔离。 | Atkinson, C. S. | N/A | CK1α, FAM83H, and FAM83B contribute to bundling of neurofilaments and are sequestered in cellular and mice models of ARSACS | |
| 细胞色素c在人类卵母细胞线粒体代谢中的作用 | Surmacki, J. M. | N/A | The role of cytochrome c in mitochondrial metabolism of human oocytes | |
| 使用可解释的机器学习理解TCR T细胞敲除行为 | Blennemann, M. | N/A | Understanding TCR T cell knockout behavior using interpretable machine learning | |
| THEMIS的CABIT2结构域的结构揭示了一种新型蛋白质折叠，其中插入了一个类似SH3的结构域 | Beyett, T. S. | N/A | Structure of the CABIT2 domain of THEMIS reveals a novel protein fold with an inserted SH3-like domain | |
| 超分辨率轴向成像用于量化活细胞中的皮牛顿牵引力 | Wang, D.-X. | N/A | Super-Resolution Axial Imaging for Quantifying Piconewton Traction Forces in Live-cells | |
| 从头设计与萘二酰亚胺结合的蛋白质，萘二酰亚胺是一种具有可调光物理性质的强效光氧化剂 | Mann, S. I. | N/A | De novo design of proteins that bind naphthalenediimides, powerful photooxidants with tunable photophysical properties | |
| 通过信息瓶颈，褶皱的睫状丛在无神经动物中塑造了展开动力学 | Brannon, C. M. | N/A | Creased ciliary flocks shape unfolding dynamics via information bottlenecks in an aneural animal | |
| 超声机械基因肿瘤预处理联合SynNotch CAR-T疗法 | Yoon, C. W. | N/A | Tumor Priming by Ultrasound Mechanogenetics for with SynNotch CAR T Therapy | |
| 水杨酸、过氧化氢酶2和AtSAP5的精细调节激发植物免疫 | Chang, L. | N/A | Delicate tuning of H2O2 by salicylic acid, catalase 2, and AtSAP5 incites plant immunity | |
| 德克萨斯A&M国际大学两个不同干扰水平地点的节肢动物多样性 | Siller, E. | N/A | Arthropod Diversity at Two Sites with Different Disturbance Levels at the Texas A&M International University | |
| 植物SCAR/WAVE功能分化的分子基础 | Brumm, S. | N/A | A molecular basis for plant SCAR/WAVE functional divergence | |
| # BioRxiv 2024-09-30 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 利用双滴定微点测定法对血清抗体反应进行深度物化表征 | Kovacs, A. | N/A | Deep physico-chemical characterization of the serum antibody response using a dual-titration microspot assay | |
| TMPRSS2对Omicron谱系Spike糖蛋白的激活受到ACE2的Collectrin样域的调控 | Aggarwal, A. | N/A | TMPRSS2 activation of Omicron lineage Spike glycoprotein is regulated by Collectrin-like domain of ACE2 | |
| 端粒通过非端粒TRF2控制人类端粒酶（hTERT）的表达。 | Sengupta, A. | N/A | Telomeres control human telomerase (hTERT) expression through non-telomeric TRF2 | |
| 测序、Ludwigia叶绿体基因组的从头组装以及在Onagraceae科内的比较分析 | Barloy-Hubler, F. | N/A | Sequencing, de novo assembly of Ludwigia plastomes, and comparative analysis within the Onagraceae family | |
| INSTINCT：通过随机域转换实现空间染色质可及性测序数据的多样本整合 | Liu, Y. | N/A | INSTINCT: Multi-sample integration of spatial chromatin accessibility sequencing data via stochastic domain translation | |
| MTALTCO1：一种由线粒体DNA编码的259个氨基酸长的替代蛋白，挑战了传统线粒体基因组学的理解。 | Robitaille, F. | N/A | MTALTCO1: a 259 amino-acid long mtDNA-encoded alternative protein that challenges conventional understandings of mitochondrial genomics | |
| 基于视频的生物力学分析捕捉到了不同神经肌肉疾病的疾病特异性运动特征。 | Ruth, P. | N/A | Video-based biomechanical analysis captures disease-specific movement signatures of different neuromuscular diseases | |
| 在稻珊瑚（Montipora capitata）中，存在一种进化上保守的Hox-Gbx分节代码 | He, S. | N/A | An evolutionarily conserved Hox-Gbx segmentation code in the rice coral Montipora capitata | |
| 慢性使用氟西汀会下调前额叶皮质中小清蛋白中间神经元的线粒体活性。 | Jetsonen, E. | N/A | Chronic treatment with fluoxetine downregulates mitochondrial activity in parvalbumin interneurons of prefrontal cortex | |
| 从结构MRI图像生成合成TSPO PET图谱 | Ferrante, M. | N/A | Generation of synthetic TSPO PET maps from structural MRI images | |
| 黑质外路易体病的模型中能量代谢改变和昼夜节律紊乱的分子特征。 | Lin, L. | N/A | Molecular signatures of altered energy metabolism and circadian rhythm perturbations in a model of extra-nigral Synucleinopathy. | |
| 成骨细胞衍生的红细胞生成素调节应激性红细胞生成过程中的肝脏铁调素 | Myneni, V. D. | N/A | Osteocyte-derived erythroferrone regulates liver hepcidin during stress erythropoiesis | |
| 芽殖酵母亚门中朊毒素样杀伤毒素的古老起源与高度多样性 | Heneghan, P. G. | N/A | Ancient origin and high diversity of zymocin-like killer toxins in the budding yeast subphylum | |
| 心肌内皮素调节心肌细胞增殖与心脏再生 | Sorensen, D. W. | N/A | Myocardial Endoglin Regulates Cardiomyocyte Proliferation and Cardiac Regeneration | |
| 在突变热点驱动的克隆性造血中未发现免疫监视的证据 | Walkowiak, B. | N/A | No evidence of immunosurveillance in mutation-hotspot driven clonal haematopoiesis | |
| UPR诱导的细胞内C5aR1通过调节肿瘤细胞命运，促进对低氧肿瘤微环境的适应。 | Suwa, T. | N/A | UPR-induced intracellular C5aR1 promotes adaptation to the hypoxic tumour microenvironment by regulating tumour cell fate | |
| 人类肺癌恶病质的新型临床前模型 | Snoke, D. B. | N/A | Novel preclinical model of human lung cancer cachexia | |
| 长非编码RNA UCA1通过含SMARCA2的SWI/SNF复合物影响人类结直肠癌中的染色质重塑。 | Neve, B. | N/A | Long non-coding RNA UCA1 affects chromatin remodeling via SMARCA2-containing SWI/SNF complex in human colorectal cancer. | |
| 打破循环：如何通过靶向CD44v6/MET信号通路破坏结直肠癌细胞的可塑性 | Sonnentag, S. J. | N/A | Breaking the cycle: How targeting CD44v6/MET signaling disrupts colorectal cancer cell plasticity | |
| 斑马鱼胶质-血管相互作用在脑发育过程中逐渐扩展 | Gall, L. G. | N/A | Zebrafish glial-vascular interactions progressively expand over the course of brain development | |
| 父母照顾会改变早期体型和生长在塑造未来生理机能中的作用 | Laubach, Z. M. | N/A | Parental care modifies the role of early-life size and growth in shaping future physiology | |
| 细菌运动模式能够平滑地适应空间限制和无序环境。 | Zhang, H. | N/A | Bacterial motility patterns adapt smoothly in response to spatial confinement and disorder | |
| 鉴定SLC45A4为编码神经元多胺转运体的疼痛基因。 | Middleton, S. J. | N/A | Identification of SLC45A4 as a pain gene encoding a neuronal polyamine transporter. | |
| 基于将听觉伪词声音映射到多个意义域的声学参数组合：一种机器学习方法 | Kumar, G. V. | N/A | Acoustic parameter combinations underlying mapping of auditory pseudoword sounds to multiple domains of meaning: a machine learning approach | |
| 当前人类神经科学研究中的报告实践 | Gard, A. M. S. | N/A | Current Reporting Practices in Human Neuroscience Research | |
| 探索儿童非感染性葡萄膜炎中的微小RNA特征：患者样本的荟萃分析与分子谱分析 | Wawrzyniak, O. | N/A | Exploring MicroRNA Signatures in Pediatric Non-infectious Uveitis: Meta-Analysis and Molecular Profiling of Patient Samples | |
| 小鼠胚胎植入前单细胞蛋白质组学揭示早期卵裂球中某些蛋白质的显著不对称性 | Yuan, Y. | N/A | Single-cell proteomics of pre-implantation mouse embryos uncovers distinct asymmetry of certain proteins among early blastomeres | |
| 代谢重编程调控斑马鱼尾鳍再生过程中的组蛋白乳酸化 | Borbinha, J. | N/A | Metabolic reprogramming regulates histone lactylation during zebrafish caudal fin regeneration | |
| GoldPolish-目标：针对长读长基因组组装的靶向抛光 | Zhang, E. | N/A | GoldPolish-Target: Targeted long-read genome assembly polishing | |
| 全血转录组分析揭示了运动神经元疾病（MND）的RNA生物标志物特征 | Koks, S. | N/A | Whole blood transcriptome profile identifies motor neurone disease (MND) RNA biomarker signatures | |
| 鉴定出利什曼原虫中一种位于基体的新型ε-微管蛋白 | Seth, A. | N/A | Identification of a novel basal body-localized epsilon-tubulin in Leishmania | |
| AFG3L2介导的蛋白水解作用在低氧条件下限制了线粒体生物合成和基因表达。 | Chandragiri, S. | N/A | AFG3L2-mediated proteolysis restricts mitochondrial biogenesis and gene expression in hypoxia | |
| 一个MEF2C转录因子网络调控糖尿病肾病中肾小球内皮细胞的增殖 | Melo Ferreira, R. | N/A | A MEF2C transcripton factor network regulates proliferation of glomerular endothelial cells in diabetic kidney disease | |
| 听觉毛细胞的静纤毛膜力学特性的动态调节通过机械转导复合体的混乱实现 | Sam George, S. | N/A | Dynamic modulation of auditory hair cell stereocilia membrane mechanics by the scrambling mechanotransduction complex | |
| ALG-1，一种微RNA的Argonaute蛋白，促进了秀丽隐杆线虫的阴门诱导过程。 | Zhen, S. | N/A | ALG-1, a microRNA argonaute, promotes vulva induction in C. elegans | |
| 从精子在卵母细胞中的运动轨迹推断，透明带和卵周间隙在促进配子融合和多精受精快速阻断中起关键作用。 | Dubois, Y. | N/A | Key roles of the zona pellucida and perivitelline space in promoting gamete fusion and fast block to polyspermy inferred from the choreography of spermatozoa in mice oocytes | |
| p24家族成员TMED9通过快速内质网应激诱导的出口途径，将错误折叠的GPI锚定蛋白从内质网清除到高尔基体。 | Ronzier, E. | N/A | The p24-family member, TMED9, clears misfolded GPI-anchored proteins from theER to the Golgi via the Rapid ER Stress-Induced Export pathway | |
| 人神经细胞图谱在发育中人脑组织中的寨卡感染：病毒发病机制、先天免疫和谱系重编程 | Stokes, C. | N/A | The Human Neural Cell Atlas of Zika Infection in developing human brain tissue: viralpathogenesis, innate immunity, and lineage reprogramming | |
| 硫化叶菌属中基于社区的DNA修复机制的新组分 | Recalde, A. | N/A | New components of the community based DNA-repair mechanism in Sulfolobales | |
| 分化方案依赖性变异性在人诱导多能干细胞衍生的内皮祖细胞功能中的表现 | Stern, B. | N/A | Differentiation Protocol-Dependent Variability in hiPSC-Derived Endothelial Progenitor Functionality | |
| 久坐生活方式导致大鼠骨骼肌氧化应激和萎缩 | Gungor, I. | N/A | Sedentary lifestyle induces oxidative stress and atrophy in rat skeletal muscle | |
| 大麻表达图谱：一个综合资源，用于大麻（Cannabis sativa L.）基因表达的整合分析 | Barbosa-Xavier, K. | N/A | Cannabis Expression Atlas: a comprehensive resource for integrative analysis of Cannabis sativa L. gene expression | |
| 神经任务状态的主动重构 | Ritz, H. | N/A | Active reconfiguration of neural task states | |
| 蜜蜂血脑屏障的超微结构组织及其与年龄的比较 | Quigley, T. | N/A | Ultrastructural Organization of the Honeybee Blood-Brain Barrier and Comparison with Age | |
| 使用统一流程对多中心大鼠感觉诱发功能磁共振成像数据集进行激活图谱绘制。 | Galteau, M. E. | N/A | Activation mapping in multi-center rat sensory-evoked functional MRI datasets using a unified pipeline. | |
| 裸盖菇素可防止小鼠初级听觉皮层对熟悉刺激的习惯化，并在反复刺激后保持对声音的敏感性。 | Lane, C. P. | N/A | Psilocybin prevents habituation to familiar stimuli and preserves sensitivity to sound following repeated stimulation in mouse primary auditory cortex. | |
| 针对神经纤毛蛋白-1以增强黑色素瘤免疫治疗：减少肿瘤进展及外周Treg介导的免疫抑制 | Khamaru, S. | N/A | Targeting Neuropilin-1 to Enhance Immunotherapy in Melanoma: Reducing Tumour Progression and Peripheral Treg-Mediated Immunosuppression | |
| 颗粒溶素抗菌活性促进结核分枝杆菌进入休眠状态 | Schmidiger, S. | N/A | Granulysin antimicrobial activity promotes dormancy in Mycobacterium tuberculosis | |
| 路杀是迁徙性帝王蝶数量下降的关键因素 | Momeni-Dehaghi, I. | N/A | Roadkill is a crucial factor in the population decline of migratory monarch butterflies | |
| 河流网络中的多种压力源：对淡水大型无脊椎动物的局部及下游影响 | Burgazzi, G. | N/A | Multiple stressors in river networks: local and downstream effects on freshwater macroinvertebrates | |
| 蝴蝶花蜜知识的三重量子飞跃：全面研究革新保护策略 | Dunlap, S. C. | N/A | Three Fold Quantum Leap in Butterfly Nectar Knowledge: A Comprehensive Study Revolutionizing Conservation Strategies | |
| 通过原生短暂低氧成像技术观察组织损伤、水肿区域及前哨淋巴结的淋巴动态。 | Mendoza, M. I. O. | N/A | Lymphatic dynamics visualized by native transient hypoxia imaging in areas of tissue damage, edema and in sentinel lymph nodes. | |
| 曲霉菌细胞壁完整性激酶MpkA影响改变菌丝材料力学性能的细胞表型 | Gray, K. | N/A | Aspergillus nidulans cell wall integrity kinase, MpkA, impacts cellular phenotypes that alter mycelial-material mechanical properties | |
| 预测透析器选择和透析液流速对胆红素清除的影响 | Novokhodko, A. | N/A | Predicting the Impact of Dialyzer Choice and Binder Dialysate Flow Rate on Bilirubin Removal | |
| 通过加权TREE-QMC方法，提高了对基因树不完整性、估计误差和系统性同源错误（homology errors）的鲁棒性。 | Han, Y. | N/A | Improved robustness to gene tree incompleteness, estimation errors, and systematic homology errors with weighted TREE-QMC | |
| 基于线粒体功能和细胞死亡模式的肝细胞癌患者MPCD指数 | Wang, L.-X. | N/A | MPCD Index for Hepatocellular Carcinoma Patients Based on Mitochondrial Function and Cell Death Patterns | |
| 通过透析环境中环糊精实现膜甾醇水平的可逆调节 | Alsayyah, C. | N/A | Reversible tuning of membrane sterol levels by cyclodextrin in a dialysis setting | |
| LC8通过异质性桥接53BP1寡聚体来增强53BP1焦点 | Howe, J. | N/A | LC8 enhances 53BP1 foci through heterogeneous bridging of 53BP1 oligomers | |
| 用于单分子显微镜的可重复使用微流控室 | Alfehaid, J. | N/A | Reusable Microfluidic Chambers for Single-Molecule Microscopy | |
| 细胞在受限迁移过程中牵引力的测量 | Hockenberry, M. A. | N/A | Measurement of cellular traction forces during confined migration | |
| 衰老和瓦螨寄生对蜜蜂血脑屏障的细胞旁通透性和跨细胞通透性的影响 | Quigley, T. P. | N/A | Effect of aging and Varroa parasitism on the paracellular and transcellular permeability of the honeybee blood-brain barrier | |
| 同步化的染色质组织作为基于麻醉的植物意识中的强效生物标志物 | Chandra, S. | N/A | Synchronized Chromatin Organization Serves as Potent Biomarker in Anaesthesia-based Plant Consciousness | |
| 通过结合免疫荧光和RNA原位杂交技术，在细胞核内同时观察到Pol II和马铃薯纺锤块茎类病毒RNA。 | Ma, J. | N/A | Simultaneous observation of Pol II and potato spindle tuber viroid RNA in the nucleus by combining immunofluorescence and RNA in situ hybridization | |
| 番茄中辣椒红素/辣椒玉红素合酶的表达改变了果实类胡萝卜素库，并增强了维生素A原的风味挥发性物质 | Fu, J. | N/A | Expression of Capsanthin/Capsorubin Synthase in Tomato Alters Fruit Carotenoid Pools, and Flavor Volatiles Enhancing Provitamin A | |
| 虚拟植物实验室：一个基于Julia的现代化植物建模框架 | Morales, A. | N/A | The Virtual Plant Laboratory: a modern plant modeling framework in Julia | |
| 在帕金森病小鼠模型中，恢复多巴胺能神经元中的Fbxo7表达可恢复酪氨酸羟化酶 | Laman, H. | N/A | Restoration of Fbxo7 expression in dopaminergic neurons restores tyrosine hydroxylase in a mouse model of Parkinson's disease | |
| LPS诱导的小鼠类谵妄行为和微胶质激活与双谱脑电图（BSEEG）相关 | Nishiguchi, T. | N/A | LPS-induced delirium-like behavior and microglial activation in mice correlate with bispectral electroencephalography (BSEEG) | |
| 当注意力受到伤害：rTMS对时间知觉神经相关性的影响 | Conto, F. | N/A | When Attention Hurts: The Effect Of rTMS On Neural Correlates Of Time Perception | |
| 蓝斑核磁共振完整性与结构体积的逆向关联及其对个体注意力不集中的影响 | Neal, J. | N/A | Inversed association of locus coeruleus MRI integrity with structural volume and its impact on individual's inattentiveness | |
| 时间压力下目标导向控制与习惯性控制之间的情境依赖性交互作用 | Froelich, S. | N/A | Context-Dependent Interaction Between Goal-Directed and Habitual Control Under Time Pressure | |
| 非侵入性大脑刺激前额极皮质可促进在类似觅食的序列选择任务中付出认知努力的意愿 | Bogdanov, M. | N/A | Non-invasive brain stimulation over the Frontopolar Cortex promotes willingness to exert cognitive effort in a foraging-like sequential choice task | |
| 全皮层θ振荡的时空模式与自由移动行为相耦合 | Sattler, N. J. | N/A | Cortex-wide spatiotemporal motifs of theta oscillations are coupled to freely moving behavior | |
| 年龄和地区特异性代谢物浓度校正的水放松图谱 | Simegn, G. L. | N/A | A Water Relaxation Atlas for Age and Region specific Metabolite Concentration Correction | |
| 通过在神经元中删除质子激活的氯离子通道，导致内体过度酸化，从而损害AMPA受体的内吞作用和长时程抑制（LTD）。 | Chen, K. | N/A | Endosomal hyper-acidification via proton-activated chloride channel deletion in neurons impairs AMPA receptor endocytosis and LTD | |
| 致幻剂假说：通过依赖回放的可塑性机制来模拟经典致幻剂的幻觉效应 | Bredenberg, C. | N/A | The oneirogen hypothesis: modeling the hallucinatory effects of classical psychedelics in terms of replay-dependent plasticity mechanisms | |
| ACE1不影响5XFAD小鼠大脑中Aβ降解或淀粉样斑块的积累 | Jeon, S. | N/A | ACE1 Does Not Influence Cerebral Aβ Degradation or Amyloid Plaque Accumulation in 5XFAD Mice | |
| 内质网应激调节因子IRE1α的激活会损害肺部宿主防御功能。 | Sharma, A. | N/A | Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses | |
| 环境机械异质性对T细胞功能的影响 | Pandit, J. J. | N/A | Effect of the Environmental Mechanical Heterogeneity on T Cell Function | |
| 损伤诱导的IL-18刺激胸腺NK细胞，限制内源性组织再生 | Granadier, D. | N/A | Damage-induced IL-18 stimulates thymic NK Cells limiting endogenous tissue regeneration | |
| 衰老的僵硬交响曲：衰老的骨细胞如何失去它们的弹性节奏 | Tilton, M. | N/A | Stiffening Symphony of Aging: How Senescent Osteocytes Lose Their Elastic Rhythm | |
| PA2G4、MCRS1和SOBP对SIX1+EYA转录活性的直接和间接调控 | Jourdeuil, K. | N/A | Direct and Indirect Regulation of SIX1+EYA Transcriptional Activity by PA2G4, MCRS1, and SOBP | |
| 在农业土壤中，线虫拮抗物的多样性及其受根结线虫密度和覆盖作物影响的可调控性 | Cazzaniga, S. G. | N/A | On the diversity of nematode antagonists in an agricultural soil, and their steerability by root-knot nematode density and cover crops | |
| 一种用于两栖动物、龟类和鱼类eDNA元条形码的新型简并引物组 | Rodgers, T. W. | N/A | A novel degenerate primer set for eDNA metabarcoding of amphibians, turtles and fish | |
| 缺氧威胁珊瑚和海葵的早期生命阶段 | Glass, B. H. | N/A | Hypoxia threatens coral and sea anemone early life stages | |
| 在中国，多样化措施减轻了农药对蜜蜂的影响，但未能减轻微塑料的影响，同时并未影响油菜籽产量。 | Lin, W. | N/A | Diversification mitigates pesticide but not microplastic effects on bees without compromising rapeseed yield in China | |
| 在近期经历过多倍体化和基因渐渗的植物属中，基因树拓扑空间的地形 | Landis, J. | N/A | The topography of gene tree topology space in a plant genus with a legacy of recent polyploidy and introgression | |
| CAYSS：用于酵母孢子分离自动流式细胞分析的软件包 | Raffoux, X. | N/A | CAYSS: package for automatic Cytometry Analysis of Yeast Spore Segregation | |
| 光合共生塑造了巨蛤的基因组结构与基因进化 | Li, R. | N/A | Photosymbiosis Shaped Animal Genome Architecture and Gene Evolution as Revealed in Giant Clams | |
| 追踪串联重复序列：一种可定制的识别和跨物种比较的管道 | de Lima Adam, C. | N/A | TRACKing Tandem Repeats: a customizable pipeline for identification and cross-species comparisons | |
| 昼行性啮齿动物——白尾黄鼠（Ammospermophilus leucurus）中，昼夜节律的同步化缺失及对周期性厌恶刺激的夜间可塑性有限 | Zhang, V. | N/A | Lack of circadian entrainment and limited nocturnal plasticity in response to a cyclic aversive stimulus in a diurnal rodent, the antelope ground squirrel (Ammospermophilus leucurus) | |
| 随着年龄增长，小鼠子宫的生物力学和组成变化 | Domingo, M. J. E. | N/A | Biomechanical and Compositional Changes in the Murine Uterus with Age | |
| 电休克疗法和磁休克疗法诱发癫痫的最佳频率 | Peterchev, A. V. | N/A | Optimal Frequency for Seizure Induction with Electroconvulsive Therapy and Magnetic Seizure Therapy | |
| 使用混合融合Transformer从CT中精炼心肌分割 | Qin, S. | N/A | Refined Myocardium Segmentation from CT Using a Hybrid-Fusion Transformer | |
| 基于模型的强化学习用于超声驱动的自主微型机器人 | Medany, M. | N/A | Model-Based Reinforcement Learning for Ultrasound-Driven Autonomous Microrobots | |
| 不同的基因调控网络调控造血干细胞和白血病干细胞 | Zhang, B. | N/A | Distinct gene regulatory networks govern hematopoietic and leukemia stem cells | |
| FragLlama：分子设计的下一个片段预测 | Che, X. | N/A | FragLlama: Next-fragment prediction for molecular design | |
| 五物种进化空间循环博弈中存在缺失和非缺失优势网络的长期物种共存 | Cliff, D. | N/A | On Long-Term Species Coexistence in Five-Species Evolutionary Spatial Cyclic Games with Ablated and Non-Ablated Dominance Networks | |
| 《你好，你好》：高效预测变构位点的数据驱动方法 | Dong, T. | N/A | Allo-Allo: Data-efficient prediction of allosteric sites | |
| LightMed：一种轻量级且基于FFT的鲁棒模型，用于对抗性弹性的医学图像分割 | Pham, V. T. | N/A | LightMed: A Light-weight and Robust FFT-Based Model for Adversarially Resilient Medical Image Segmentation | |
| 利用荧光相关光谱技术对体外裂解液中合成的蛋白质进行实时亲和力测量的方法 | Liu, C. | N/A | Real-time affinity measurements of proteins synthesized in cell-free lysate using fluorescence correlation spectroscopy | |
| 单克隆抗体与两亲性聚合物在气-水界面上的竞争吸附 | Hingst, E. J. | N/A | Competitive Adsorption of a Monoclonal Antibody and Amphiphilic Polymers to the Air-Water Interface | |
| RapA 打开 RNA 聚合酶夹，以破坏终止后复合物并防止形成细胞毒性 R 环。 | Brewer, J. J. | N/A | RapA opens the RNA polymerase clamp to disrupt post-termination complexes and prevent cytotoxic R-loop formation | |
| 细胞内细胞器在运输途径中的主动形态动力学 | Rautu, S. A. | N/A | Active morphodynamics of intracellular organelles in the trafficking pathway | |
| 冷冻电镜展示了驱动蛋白激活途径的多个步骤 | Kendrick, A. | N/A | Cryo-EM visualizes multiple steps of dynein activation pathway | |
| 纳米团簇介导的巨噬细胞炎症反应中FcγR与TLR4之间的信号交叉对话 | Lee, S. | N/A | Nanocluster-Mediated Signaling Crosstalk between FcγR and TLR4 in Macrophage Inflammatory Responses | |
| 潜在的TGF-β具有一种域交换的结构。 | Jin, M. | N/A | Latent-TGF-β has a domain swapped architecture | |
| 不同的神经内分泌亚型预测治疗诱导的神经内分泌前列腺癌预后，并为个性化治疗提供线索 | Hong, Y.-C. | N/A | Distinct neuroendocrine subtypes predict treatment-induced neuroendocrine prostate cancer prognosis and provide clues for personalized treatment | |
| 茎水含量对于在地中海气候下热浪期间支持果树功能至关重要。 | Rez, L. | N/A | Stem water content is crucial to support fruit tree functioning during heatwaves in a Mediterranean climate | |
| 野生葡萄品种对气候变化的适应动态有助于培育具有气候适应性的葡萄及其砧木。 | Zhang, M. | N/A | The dynamics of wild Vitis species in response to climate change facilitate the breeding of grapevine and its rootstocks with climate resilience | |
| 整合耐寒性和抗去驯化能力表明葡萄藤对寒冷积累的保守反应。 | Londo, J. P. | N/A | Integrating cold hardiness and deacclimation resistance demonstrates a conserved response to chilling accumulation in grapevines. | |
| 利用自然低氧应答因子设计的反馈机制增强了合成低氧生物传感器 | Dreyer, K. S. | N/A | Engineered Feedback Employing Natural Hypoxia-Responsive Factors Enhances Synthetic Hypoxia Biosensors | |
| 氧化还原信号在脂肪组织分泌组中炎症细胞因子诱导的脂肪前体细胞分化中起介导作用 | Wager, J. L. | N/A | Redox Signaling Mediates Differentiation of Adipose Progenitors in Response to Inflammatory Cytokines in the Adipose Tissue Secretome | |
| 艾森侧抑制任务中行为和电生理标记的重测信度和重复性 | Bogdanov, M. | N/A | Test-Retest Reliability and repeatability of Behavioral and Electrophysiological Markers in an Eriksen Flanker Task | |
| 评估基于头皮的DLPFC定位方法用于TMS治疗：EEG帽F3、光束F3、CPC F3及调整后的光束F3 | Jiang, Y. | N/A | Evaluation of scalp-based targeting methods of DLPFC for TMS therapy: EEG cap F3, Beam F3, CPC F3, and adjusted Beam F3 | |
| 系统性催产素和β3受体激动剂（CL 316243）治疗对雄性饮食诱导肥胖大鼠体重和脂肪含量的影响 | Slattery, J. D. | N/A | Effects of systemic oxytocin and beta-3 receptor agonist (CL 316243) treatment on body weight and adiposity in male diet-induced obese rats | |
| 利用扩散磁共振成像技术在体内绘制人脑皮层微观结构图 | Sadikov, A. | N/A | Mapping the Microstructure of Human Cerebral Cortex In Vivo with Diffusion MRI | |
| 状态和特质血清素变化相互作用，塑造了大脑的内在连接性和梯度结构：一项结合TPH2遗传学和色氨酸耗竭的研究 | Wang, L. | N/A | State and trait serotonin variations interact to shape the intrinsic connectivity and gradient architecture of the brain: a combined TPH2 genetics and tryptophan depletion study | |
| 元控制状态的神经生理动力学：脑电图对冲突调节的洞察 | Wang, X. | N/A | Neurophysiological Dynamics of Metacontrol States: EEG Insights into Conflict Regulation | |
| 雄性小鼠在寻求奖励过程中伏隔核神经元的时序动力学 | Schall, T. A. | N/A | Temporal Dynamics of Nucleus Accumbens Neurons in Male Mice During Reward Seeking | |
| 左旋多巴在体外损害感觉神经元的溶酶体功能 | Olaoye, O. J. | N/A | Levodopa impairs lysosomal function in sensory neurons in vitro | |
| 人类CaV2.1通道的可用性背后隐藏着丰富的构象多样性。 | Wang, K. | N/A | A rich conformational palette underlies human CaV2.1-channel availability | |
| 靶向组织的初免/加强/维持治疗性单纯疱疹病毒疫苗保护HLA-A*0201转基因兔免受复发性眼部疱疹疾病的侵害 | Chentoufi, A. | N/A | Tissue-Targeted Prime/Pull/Keep Therapeutic Herpes Simplex Virus Vaccine Protect Against Recurrent Ocular Herpes Diseases in HLA-A*0201 Transgenic Rabbits | |
| 探索UVB敏感性与系统性红斑狼疮活动性之间的关联：深入了解紫外线B驱动的红斑狼疮发病机制 | He, J. | N/A | Exploring the Correlation Between UVB Sensitivity and SLE Activity: Insights into UVB-Driven Pathogenesis in Lupus Erythematosus | |
| 缺氧条件下的效应T细胞具有与非应答性黑色素瘤患者中发现的肿瘤应激T细胞相似的转录组改变。 | Nagy, M. Z. | N/A | Effector T Cells under Hypoxia have an Altered Transcriptome Similar to Tumor-Stressed T Cells Found in Non-Responsive Melanoma Patients | |
| 体内T细胞共调节因子B7-H4的成像揭示了前列腺癌中的促肿瘤巨噬细胞状态 | Kumar, M. | N/A | In vivo imaging of T-cell coregulator B7-H4 reveals protumor macrophage status in prostate cancer | |
| 利用新型自噬体分离方法对饥饿和运动期间自噬货物谱的表征 | Liu, Y. | N/A | Characterization of Autophagy Cargo Profiles during Starvation and Exercise with a Novel Autophagosome Isolation Method | |
| 结肠炎症的性别差异是由上皮特异性表达的雌激素受体α驱动的。 | Pereda, G. A. | N/A | Sex differences in colonic inflammation are driven by epithelial-specific expression of estrogen receptor alpha | |
| 利用cardiodeleter系统优化快速且稳健地生成斑马鱼心肌细胞特异性crispr的方法 | Keeley, S. | N/A | Optimization of methods for rapid and robust generation of cardiomyocyte-specific crispants in zebrafish using the cardiodeleter system | |
| 全球模式、驱动因素及羊膜动物代谢特征的影响 | Yang, Q. | N/A | Global patterns, drivers and impacts of metabolic traits across amniotes | |
| 早期人属生物进入东南亚地区引发了主要人类疟疾病媒的进化。 | Singh, U. S. | N/A | Early hominin arrival in Southeast Asia triggered the evolution of major human malaria vectors | |
| 高吞吐量靶向扩增子筛选工具，用于直接从样本中表征金黄色葡萄球菌宿主内多样性 | Furstenau, T. N. | N/A | High-throughput targeted amplicon screening tool for characterizing intrahost diversity in Staphylococcus aureus directly from sample | |
| 微流体法制备的超薄、可操作胶原蛋白片材表现出趾跟拉伸行为 | Zhang, Y. | N/A | Microfluidic Formation of Ultrathin, Handleable Collagen Sheets Exhibiting Toe-heel Tensile Behavior | |
| 依赖于浓度的CsrA对uxuB转录本的调控导致转录后BANDPASS滤波器的形成 | Rojano-Nisimura, A. M. | N/A | Concentration dependent CsrA regulation of the uxuB transcript leads to development of post-transcriptional BANDPASS Filter | |
| 追踪骨细胞衰老：骨细胞细胞骨架力学和形态的时变变化 | Liao, J. | N/A | Tracing Cellular Senescence in Bone: Time-Dependent Changes in Osteocyte Cytoskeleton Mechanics and Morphology | |
| 环氧合酶-2的破坏易导致保留射血分数的心力衰竭 | Ricciotti, E. | N/A | Cyclooxygenase-2 disruption predisposes to heart failure with preserved ejection fraction | |
| 以非蛋白质氨基酸为测试案例，采用一种新的化学分类学方法 | Gibson, M. | N/A | A new spin on chemotaxonomy using non-proteogenic amino acids as a test case | |
| 成年创伤性脑损伤后，使用脂多糖进行免疫挑战会迅速改变神经炎症和肠道微生物群，但对慢性结果影响甚微。 | Rewell, S. S. J. | N/A | A post-injury immune challenge with lipopolysaccharide following adult traumatic brain injury alters neuroinflammation and the gut microbiome acutely, but has little effect on chronic outcomes | |
| 初级视觉皮层中视觉空间的深度图 | He, Y. | N/A | A depth map of visual space in the primary visual cortex | |
| 在循环网络中，序列神经活动的自发涌现与漂移 | Shao, S. | N/A | Spontaneous emergence and drifting of sequential neural activity in recurrent networks | |
| 解读激活和共刺激抗体在纳米尺度聚集对T细胞激活的作用 | Le Saux, G. | N/A | Deciphering the role of the nanoscale clustering of activating and costimulatory antibodies on T cell activation | |
| 利用CRISPR激活技术快速评估人类多能干细胞中的基因编辑产物 | Wu, Y. | N/A | Leveraging CRISPR activation for rapid assessment of gene editing products in human pluripotent stem cells | |
| 利用时间动力学的定量相位成像预测造血干细胞的多样性 | Yogo, T. | N/A | Quantitative phase imaging with temporal kinetics predicts hematopoietic stem cell diversity | |
| 多用途动态体积生物成像的多功能光场显微平台 | Bai, Y. | N/A | A Versatile Light Field Microscopy Platform for Multi-purpose Dynamic Volumetric Bio-imaging | |
| 冠蜥（Correlophus ciliatus）染色体水平基因组组装与注释：一种无法再生尾巴的蜥蜴 | Gumangan, M. | N/A | Chromosome-level genome assembly and annotation of the crested gecko, Correlophus ciliatus, a lizard incapable of tail regeneration | |
| 改善土壤中病毒的可视化 | Parvate, A. D. | N/A | Improving the visualization of viruses in soil | |
| 铜绿微囊藻暴露于大薸和水葫芦水提液的生理响应 | Silva, L. d. O. | N/A | Physiological response of Microcystis aeruginosa exposed to aqueous extracts of Pistia stratiotes and Pontederia crassipes | |
| 一种前所未有的微小RNA-核开关相互作用控制着一种双功能泵的表达，这种泵对金黄色葡萄球菌感染至关重要。 | Gonzalez-Espinoza, G. | N/A | An unprecedented small RNA-riboswitch interaction controls expression of a bifunctional pump that is essential for Staphylococcus aureus infection | |
| 嗜热绿弯菌外膜小泡可能是生物硫运输的重要途径。 | Noundou, V. L. | N/A | Chlorobaculum tepidum Outer Membrane Vesicles Are Likely a Significant Route for Biogenic Sulfur Transport. | |
| 饮食中的L-3,4-二羟基苯丙氨酸（L-DOPA）增强了按蚊外骨骼的黑色素化，同时缩短了它们的寿命并减少了疟原虫的负担。 | Camacho, E. | N/A | Dietary L-3,4-dihydroxyphenylalanine (L-DOPA) augments cuticular melanization in Anopheles mosquitos while reducing their lifespan and malaria parasite burden | |
| 普拉梭菌调节C57BL/6小鼠肠道微生物群的碳水化合物代谢功能 | Geng, P. | N/A | Faecalibacterium prausnitzii regulates carbohydrate metabolic functions of the gut microbiome in C57BL/6 mice | |
| 长读宏基因组学能够精确追踪细菌菌株及其在粪菌移植后的基因组变化。 | Fan, Y. | N/A | Long-read metagenomics empowers precise tracking of bacterial strains and their genomic changes after fecal microbiota transplantation | |
| 新型抗碳青霉烯类肺炎克雷伯菌噬菌体的特性分析 | Kim, B. | N/A | Characterization of newly isolated bacteriophages targeting carbapenem-resistant Klebsiella pneumoniae | |
| 在2019年至2021年间，法国诺曼底地区解剖的马科动物中，艰难梭菌的感染情况：产毒菌株的普遍携带及新兴的017型菌株的毒力 | Petry, S. | N/A | Clostridioides difficile in Equidae necropsied in Normandie, France from 2019 to 2021: common carriage of toxigenic strains and virulence of emerging ribotype 017 | |
| Typhi Mykrobe：直接从序列读取中快速且准确地识别伤寒沙门氏菌的谱系及抗菌药物耐药性基因分型 | Ingle, D. J. | N/A | Typhi Mykrobe: fast and accurate lineage identification and antimicrobial resistance genotyping directly from sequence reads for the typhoid fever agent Salmonella Typhi | |
| 两个跨膜转录调节因子协同作用，激活了霍乱弧菌中由几丁质诱导的自然转化过程。 | Hullinger, A. C. | N/A | Two transmembrane transcriptional regulators coordinate to activate chitin-induced natural transformation in Vibrio cholerae | |
| 二萜类植物抗毒素塑造了水稻根系微生物群及其与根寄生线虫的关联 | Kudjordjie, E. N. | N/A | Diterpenoid phytoalexins shape rice root microbiomes and their associations with root parasitic nematodes | |
| 一项针对多种土壤类型和地理区域抗生素抗性的宏基因组研究 | Pillay, S. | N/A | A Metagenomic Study of Antibiotic Resistance Across Diverse Soil Types and Geographical Locations | |
| 一种宿主导向的佐剂可复苏并增强抗生素对胞内细菌持留菌的敏感性。 | Lu, K.-Y. | N/A | A host-directed adjuvant resuscitates and sensitizes intracellular bacterial persisters to antibiotics | |
| NPC1L1介导的27-羟基胆固醇代谢在骨质疏松发生发展中的机制 | Li, B. | N/A | Mechanism of NPC1L1 mediated 27-hydroxycholesterol metabolisms in the occurrence and development of osteoporosis | |
| 生物固体改良对土壤抗性组和微生物组的影响 - 温室研究 | Ste.Marie, J. P. | N/A | Impact of biosolids amendment on the soil resistome and microbiome - a greenhouse study | |
| 一种用于心脏特异性基因沉默的腺嘌呤碱基编辑器的多功能AAV载体 | Liu, Z. | N/A | An all-in-one AAV vector for cardiac-specific gene silencing by an adenine base editor | |
| 伏隔核电刺激后脑分子景观的变化 | Cai, C. | N/A | Change in brain molecular landscapes following electrical stimulation of the nucleus accumbens | |
| 马洛：利用从头肽段鉴定技术对法医学中的未知样本进行分类表征 | Jenson, S. C. | N/A | MARLOWE: Taxonomic Characterization of Unknown Samples for Forensics Using De Novo Peptide Identification | |
| 高通量多样化蛋白质-配体表面以发现化学诱导接近剂 | Shaum, J. B. | N/A | High-throughput diversification of protein-ligand surfaces to discover chemical inducers of proximity | |
| 体内碘代酪氨酸尿代谢物的鉴定与测定 | Ji, C. X. | N/A | Identification and determination of the urinary metabolite of iodotyrosine in vivo | |
| 甲烷产生古菌Methanococcus maripaludis中的糖原磷酸化酶：一种不依赖吡哆醛5'-磷酸的磷酸化酶的独特调节特性 | Gonzalez-Ordenes, F. | N/A | Glycogen phosphorylase from the methanogenic archaeon Methanococcus maripaludis: Unique regulatory properties of a pyridoxal 5'-phosphate independent phosphorylase | |
| 持续性和爆发性电微刺激对皮层兴奋性和抑制性神经元激活的时空特性 | Hughes, C. | N/A | Spatiotemporal properties of cortical excitatory and inhibitory neuron activation by sustained and bursting electrical microstimulation | |
| 基于核酶的生物传感器用于植物基因表达成像 | Liu, Y. | N/A | Ribozyme-based biosensor for imaging gene expression in plants | |
| 以线粒体为中心的包涵体肌炎代谢组图谱：中心碳代谢的性别特异性改变 | Naddaf, E. | N/A | Mitochondria-centered metabolomic map of inclusion body myositis: sex-specific alterations in central carbon metabolism | |
| 将地理空间工具整合于绘制坦桑尼亚鲁索托西乌桑巴拉山森林火灾严重程度和烧毁区域图 | Mkiwa, B. P. | N/A | Integrating geospatial tools in mapping forest fire severity and burned areas in the Western Usambara Mountain Forests, Lushoto, Tanzania | |
| FIGL1限制了拟南芥中减数分裂非交叉事件的形成 | Charif, D. | N/A | FIGL1 limits the formation of meiotic non crossover events in Arabidopsis thaliana | |
| 一种导致常染色体显性肥厚型心肌病的ALPK3截短变异体通过马瓦卡姆汀部分得到挽救 | Leinhos, L. | N/A | An ALPK3 truncation variant causing autosomal dominant hypertrophic cardiomyopathy is partially rescued by mavacamten | |
| 通过多巴胺交联稳定模拟胶原蛋白三螺旋及其组装结构 | Cole, C. C. | N/A | Covalent Stabilization of Collagen Mimetic Triple Helices and Assemblies by Dopa Crosslinking | |
| 组织特异性和空间依赖性的代谢特征在骨骼成熟的雄性和雌性C57Bl/6J小鼠中因损伤而受到干扰 | Welhaven, H. D. | N/A | Tissue-specific and spatially dependent metabolic signatures perturbed by injury in skeletally mature male and female C57Bl/6J mice | |
| 恶性疟原虫NCR1膜蛋白是一种新型抗疟疾靶点，负责将胆固醇输出以维持膜稳态。 | Zhang, Z. | N/A | The Plasmodium falciparum NCR1 membrane protein is a novel antimalarial target that exports cholesterol to maintain membrane homeostasis | |
| 选择性波段红外脉冲回波光谱（Band-selective IR PRESS）用于脑肿瘤光谱分析，能够稳健地检测乳酸。 | Kishimoto, S. | N/A | Band-selective IR PRESS for brain tumor spectroscopy allows robust detection of lactate | |
| R2DT：一个用于可视化RNA二级结构的全面平台 | McCann, H. | N/A | R2DT: a comprehensive platform for visualising RNA secondary structure | |
| 早期呼吸道合胞病毒感染对特定细胞类型气道DNA甲基化的影响 | McKennan, C. | N/A | Impact of early-life respiratory syncytial virus infection on cell type-specific airway DNA methylation | |
| # BioRxiv 2024-09-29 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 后顶叶皮层中的分隔树突可塑性整合了跨越时间的记忆 | Sehgal, M. | N/A | Compartmentalized dendritic plasticity in the retrosplenial cortex integrates memories across time | |
| 呼叫模式在狨猴中编码和传递情感 | Huang, J. | N/A | Call patterns encode and transmit emotion in marmoset monkeys | |
| 活跃的树突能够在时间抖动的情况下实现鲁棒的尖峰计算 | Burger, T. S. | N/A | Active Dendrites Enable Robust Spiking Computations despite Timing Jitter | |
| AAA+蛋白Msp1通过疏水性错配识别底物。 | Fresenius, H. L. | N/A | The AAA+ protein Msp1 recognizes substrates by a hydrophobic mismatch | |
| 氯霉素和庆大霉素通过抑制大肠杆菌C LPS突变体的一个子集，减少了噬菌体{Phi}X174的抗性进化。 | Parab, L. | N/A | Chloramphenicol and gentamicin reduce resistance evolution to phage {Phi}X174 by suppressing a subset of E. coli C LPS mutants | |
| KaryoTap 实现数千个单个人类细胞的非整倍体检测 | Mays, J. C. | N/A | KaryoTap Enables Aneuploidy Detection in Thousands of Single Human Cells | |
| 将恐惧重新引入边际价值理论：风险-边际价值理论与最佳胆量 | Calcagno, V. | N/A | Taking fear back into the Marginal Value Theorem: the risk-MVT and optimal boldness | |
| 定量全基因组模型揭示可解释的全基因组关联 | Ruzickova, N. | N/A | Quantitative omnigenic model discovers interpretable genome-wide associations | |
| 上皮力学的贝叶斯参数推断 | Yan, X. | N/A | Bayesian parameter inference for epithelial mechanics | |
| 特定的有丝分裂事件驱动细胞骨架重塑，这是左右器官发育所必需的 | Wu, Y. | N/A | Specific Mitotic Events Drive Cytoskeletal Remodeling Required for Left-Right Organizer Development | |
| 级联反向积分反馈基序用于提高鲁棒稳定性和性能 | M. Zand, A. | N/A | Cascaded Antithetic Integral Feedback Motifs for Robust Stability and Performance Improvement | |
| Lphn1敲除抑制结直肠癌机制的研究 | wang, Y. | N/A | Research on the Mechanism of Lphn1 Knockout in Inhibiting Colorectal Cancer | |
| 果蝇母体向合子转变过程中先锋因子结合动力学的批量级图谱 | Dima, S. S. | N/A | Bulk-level maps of pioneer factor binding dynamics during Drosophila maternal-to-zygotic transition | |
| 猴子预测美国大选 | Jiang, Y. | N/A | Monkeys Predict US Elections | |
| 波兰乳牛中分离出的多杀性巴氏杆菌和溶血性曼海姆菌的抗菌药物抗性和毒力相关基因，这些乳牛表现出牛呼吸道疾病的症状 | Lachowicz-Wolak, A. | N/A | Antimicrobial Resistance and Virulence-Associated Genes of Pasteurella multocida and Mannheimia haemolytica Isolated from Polish Dairy Calves with Symptoms of Bovine Respiratory Disease | |
| 视觉雪花综合征患者的定向运动敏感性受到拖尾型后像存在的影响而发生调节。 | Obukhova, T. S. | N/A | Directional motion sensitivity in people with Visual Snow Syndrome is modulated by the presence of trailing-type palinopsia | |
| 在人为影响下的农产品中发现了“不为人知”的抗生素抗性 | Davidovich, C. | N/A | Occurrence of "under-the-radar" antibiotic resistance in anthropogenically affected produce | |
| CCR5拮抗剂作为神经保护和卒中恢复增强剂：一项临床前系统评价和荟萃分析 | Sharif, A. | N/A | CCR5 antagonists as neuroprotective and stroke recovery enhancing agents: a preclinical systematic review and meta-analysis | |
| 解开睫状衣：睫状糖萼的高分辨率结构与功能 | Hoepfner, L. M. | N/A | Unwrapping the ciliary coat: high-resolution structure and function of the ciliary glycocalyx | |
| 连接酶介导的可编程基因组整合（L-PGI）：一种克服逆转录酶为基础的编辑系统局限性的高效位点特异性基因编辑系统 | Nan, A. X. | N/A | Ligase-mediated programmable genomic integration (L-PGI): an efficient site-specific gene editing system that overcomes the limitations of reverse transcriptase-based editing systems | |
| 母亲行为的自然变化会影响后代特质焦虑和海马神经发生 | Grieco, F. | N/A | Natural variations in maternal behaviour shape trait anxiety and hippocampal neurogenesis in offspring | |
| Dnmt1在腹侧苍白球中间神经元中的缺失会改变皮层回路功能，并导致类似抑郁的行为。 | Linde, J. | N/A | Dnmt1-deficiency in PV interneurons alters cortical circuit function and leads to depression-like behavior | |
| 评估美国模拟非洲猪瘟疫情中的采样和实验室能力 | Galvis, J. A. | N/A | Estimating sampling and laboratory capacity for a simulated African swine fever outbreak in the United States | |
| 利用金属诱导能量转移成像/光谱技术测量活细胞中膜的三维动力学 | Chen, T. | N/A | Measuring 3-dimensional dynamics of membrane in living cell with metal-induced energy transfer imaging/spectroscopy | |
| 安非他命通过破坏前额叶的渐进活动来增加时间变异性。 | Weber, M. A. | N/A | Amphetamine increases timing variability by degrading prefrontal ramping activity | |
| HIV感染和治疗中免疫细胞的代谢重编程 | Wu, D. | N/A | Metabolic reprogramming of immune cells in HIV infection and treatment | |
| 结核分枝杆菌在病原体特异性免疫下生存的遗传需求 | James, K. S. | N/A | Genetic requirements of Mycobacterium tuberculosis for survival under pathogen-specific immunity | |
| 跨王国互动与环境对重度低龄儿童龋齿口腔微生物群的影响 | Weng, L. | N/A | Inter-Kingdom Interactions and Environmental Influences on the Oral Microbiome in Severe Early Childhood Caries | |
| 功能性状预测了在气候变暖条件下当前和新颖竞争的结果 | Lyu, S. | N/A | Functional traits predict outcomes of current and novel competition under warmer climate | |
| mTORC1和STAT3信号通路对于体外TGFβ1依赖的三维（3D）肌腱构建体的形成是不可或缺的。 | Koo, B. | N/A | mTORC1 and STAT3 signalings are indispensable for in vitro TGFβ1-dependent Three-Dimensional (3D) tendon construct. | |
| p53Y217C的致癌和致畸效应，这是一种模拟人类热点突变p53Y220C的小鼠模型 | Jaber, S. | N/A | Oncogenic and teratogenic effects of p53Y217C, a mouse model of the human hotspot mutant p53Y220C | |
| 透明细胞肾细胞癌肿瘤血栓相关mRNA可变剪接的特征分析 | Cohen, Z. | N/A | Characterization of alternative mRNA splicing associated with tumor thrombus in clear-cell renal cell carcinoma | |
| 癌症中热力学失稳酪氨酸磷酸化的快速预测 | Woodard, J. C. | N/A | Rapid prediction of thermodynamically destabilizing tyrosine phosphorylations in cancers | |
| 大麻烟雾和口服Δ9THC能增强老年受试者的工作记忆，但对年轻成年受试者则无此效果。 | Zequeira, S. | N/A | Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects | |
| 洞穴适应有利于墨西哥脂鲤的衰老韧性 | Cobham, A. E. | N/A | Cave Adaptation Favors Aging Resilience in the Mexican Tetra | |
| 敲除SfVipR1基因可使甜菜夜蛾对苏云金芽孢杆菌Vip3Aa毒素产生高水平抗性。 | Zhang, Z. | N/A | Knockout of the SfVipR1 gene confers high-level resistance to Bacillus thuringiensis Vip3Aa toxin in Spodoptera frugiperda | |
| 衰老的食管上皮细胞中，先前的NOTCH1突变改变了体细胞突变的选择。 | Jones, P. H. | N/A | Somatic mutant selection is altered by prior NOTCH1 mutation in aging esophageal epithelium | |
| 软骨下骨髓脂肪组织脂解作用调控手骨关节炎中的骨形成 | Maniglio, M. | N/A | Subchondral bone marrow adipose tissue lipolysis regulates bone formation in hand osteoarthritis | |
| 代谢应激加速了骨关节炎中失调的滑膜巨噬细胞-成纤维细胞通讯及Htra1的过度产生 | Blackler, G. | N/A | Metabolic Stress Accelerates Dysregulated Synovial Macrophage-Fibroblast Communication and Htra1 Overproduction in Osteoarthritis | |
| 延长IKK激活的时间变化刺激促进了核重塑和NF-κB动力学的机制转换 | Smeal, S. W. | N/A | Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics | |
| 旁系同源蛋白补偿在癌症中基因丢失后维持蛋白质相互作用网络 | Venkatesh, A. | N/A | Paralog protein compensation preserves protein-protein interaction networks following gene loss in cancer | |
| 增强型AAV工具箱，用于访问和扰动纹状体细胞类型及回路 | Hunker, A. C. | N/A | Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits | |
| 分子与神经回路机制：果蝇性经验依赖的长时记忆 | Sun, D. | N/A | Molecular and Neural Circuit Mechanisms Underlying Sexual Experience-dependent Long-Term Memory in Drosophila. | |
| 青年时期个性化功能网络地形中可重复的性别差异 | Keller, A. S. | N/A | Reproducible Sex Differences in Personalized Functional Network Topography in Youth | |
| 用于评估啮齿动物前肢功能的运动偏差指数（KDI） | Espin, A. T. | N/A | A Kinematic Deviation Index (KDI) for Evaluation of Forelimb Function in Rodents | |
| 同源异型结构域蛋白编码在果蝇视觉系统的第一神经节中规定了神经元的多样性 | Xu, C. | N/A | Homeodomain protein codes specify neuronal diversity in the first ganglion of the Drosophila visual system | |
| 人类乳腺癌中转座元件的可变剪接 | Nesta, A. V. | N/A | Alternative splicing of transposable elements in human breast cancer | |
| EmbedSimScore：通过结构和上下文嵌入推进蛋白质相似性分析 | Saha, G. | N/A | EmbedSimScore: Advancing Protein Similarity Analysis with Structural and Contextual Embeddings | |
| 果蝇在特征贫乏环境中的空间学习 | Chen, Y. | N/A | Spatial learning in feature-impoverished environments in Drosophila | |
| 绘制并构建多相核仁的RNA调控结构 | Quinodoz, S. A. | N/A | Mapping and engineering RNA-controlled architecture of the multiphase nucleolus | |
| 微流控调节显微解剖肿瘤中的微血管 | Nguyen, T. N. H. | N/A | Microfluidic Modulation of Microvasculature in Microdissected Tumors | |
| 柠檬黄不能使活体组织变得透明 | Inagaki, S. | N/A | Tartrazine cannot make live tissues transparent | |
| ABA调控的JAZ1蛋白通过结合NAC42转录因子抑制植物中植保素生物合成的激活 | Lin, J. | N/A | ABA-regulated JAZ1 Proteins Bind NAC42 Transcription Factors to Suppress the Activation of Phytoalexin Biosynthesis in Plants | |
| 生物学启发的皮层模型预测光遗传学扰动 | Sourmpis, C. | N/A | Biologically informed cortical models predict optogenetic perturbations | |
| 运动检测任务中的目标与干扰项的节奏采样与竞争 | Xiong, C. | N/A | Rhythmic Sampling and Competition of Target and Distractor in a Motion Detection Task | |
| 病毒性流行病的潜在风险在蝙蝠的系统发育树上并非均匀分布 | Cummings, C. A. | N/A | Viral epidemic potential is not uniformly distributed across the bat phylogeny | |
| 无目标的CUT&Tag和BG4 CUT&Tag均在G四链体和可接近的染色质区域富集。 | Thompson, M. D. | N/A | Untargeted CUT&Tag and BG4 CUT&Tag are both enriched at G-quadruplexes and accessible chromatin | |
| 用于引导组织组织和再生的具有微观形貌的多尺度支架的3D打印 | Fu, R. | N/A | 3D Printing of Multiscale Scaffolds with Microtopography for Guiding Tissue Organization and Regeneration | |
| 使用从人脑死后组织中分离的微血管构建的解剖学和生理学上准确的工程化神经血管单元和血脑屏障模型 | O'Grady, B. | N/A | Anatomically and Physiologically Accurate Engineered Neurovascular Unit and Blood-Brain Barrier Model Using Microvessels Isolated from Postmortem Human Brain Tissue | |
| 使用单细胞多组学数据集对拷贝数畸变推断工具进行基准测试 | Song, M. | N/A | Benchmarking copy number aberrations inference tools using single-cell multi-omics datasets | |
| 研究超声驱动激励微泡产生的复杂微流场中剪切应力下的细胞活力 | Bakhtiari, A. | N/A | Investigating Cell Viability under Shear Stress in Complex Microstreaming Flows Generated by Ultrasound-Driven Actuated Microbubbles | |
| 异常血管系统减少了肿瘤计算模型中药物与氧气的重叠：对治疗效果的影响 | Enjalbert, R. | N/A | Abnormal vasculature reduces overlap between drugs and oxygen in a tumour computational model: implications for therapeutic efficacy | |
| 没有超螺旋扭曲的胶原蛋白三螺旋 | Kreutzberger, M. A. B. | N/A | A Collagen Triple Helix without the Super Helical Twist | |
| 经过田间试验的HaHB11和HaHB4大豆品种表现出增加的籽粒数量和在生殖阶段增强的耐热性。 | Raineri, J. | N/A | Field-tested HaHB11 and HaHB4 soybean exhibit increased grain number and heat tolerance at the reproductive stage | |
| 通过比较不同行为群体的雄性和雌性个体，高估了性差异在精神兴奋剂活性中的作用。 | Tigano, A. M. | N/A | Overestimation of sex differences in psychostimulant activity via comparisons of males and females from different behavioral groups. | |
| AMPK激动剂优化了嵌合抗原受体T细胞在体内的持久性和抗白血病疗效。 | Braverman, E. | N/A | AMPK agonism optimizes the in vivo persistence and anti-leukemia efficacy of chimeric antigen receptor T cells | |
| 用于昆虫运动中肢体运动学本体感觉的尖峰神经网络模型 | van der Veen, T. | N/A | A spiking neural network model for proprioception of limb kinematics in insect locomotion | |
| 在存在竞争性细菌病原体的情况下进行噬菌体引导 | Gurney, J. | N/A | Phage Steering in the Presence of a Competing Bacterial Pathogen | |
| 硝唑酮通过DNA损伤和应激反应途径对棘阿米巴卡氏虫具有杀阿米巴活性 | Chen, L. | N/A | Nitroxoline evidence Amoebicidal Activity against Acanthamoeba castellanii through DNA damage and the stress response pathways | |
| 流感病毒感染细胞的病毒液滴中，段间相互作用的形成依赖于浓度 | Takizawa, N. | N/A | Concentration-dependent formation of intersegment interactions in viral droplets of influenza A virus infected cells | |
| 体外研究洛雷斯坦特有植物阿月浑子叶水醇提取物的化学成分及抗龋齿细菌的抗菌活性 | Rahimi, M. | N/A | In vitro study of chemical compositions and antibacterial activity of Lorestan endemic plant, Pistacia atlantica leaf hydroalcoholic extract against cariogenic bacteria | |
| 组蛋白残基H3K56与错配修复蛋白MutSβ之间的相互作用驱动CAG重复序列的扩展 | Guo, J. | N/A | Interaction between histone residue H3K56 and mismatch repair protein MutSβ drives CAG repeat expansion | |
| VirtualIce: 半合成冷冻电镜显微图生成器 | Noble, A. J. | N/A | VirtualIce: Half-synthetic CryoEM Micrograph Generator | |
| H3K9甲基化非依赖性活性在异染色质焦点、基因抑制和器官发生中的HPL-2/HP1作用 | Delaney, C. E. | N/A | H3K9 methylation-independent activity for HPL-2/HP1 in heterochromatin foci, gene repression, and organogenesis | |
| 近端H3K14泛素化对组蛋白H3K9甲基转移酶Clr4的刺激机制探究 | Du, Y. | N/A | Mechanistic Insights into the Stimulation of the Histone H3K9 Methyltransferase Clr4 by Proximal H3K14 Ubiquitination | |
| 拟南芥减数分裂中MutL复合体的遗传解剖 | Kbiri, N. | N/A | Genetic dissection of MutL complexes in Arabidopsis meiosis | |
| 对跨越生命树的118,065个基因组中的发夹环和十字形结构进行特征分析 | Chantzi, N. | N/A | Characterization of hairpin loops and cruciforms across 118,065 genomes spanning the tree of life | |
| Sirtuin 6是一种组蛋白去乙酰化酶。 | Nickel, G. A. | N/A | Sirtuin 6 is a histone delactylase | |
| FID与否：在HPC中应用GANs进行MRI图像生成 | Cepa, B. | N/A | To FID or not to FID: Applying GANs for MRI Image Generation in HPC | |
| 计算机模拟识别和建模针对T型钙通道的FDA批准药物 | Pedro, F. | N/A | In Silico identification and modelling of FDA-approved drugs targeting T-type calcium channels | |
| 谷氨酸盐转运蛋白和代谢酶是浸润性乳腺小叶癌的不良预后因素 | Young, T. A. | N/A | Glutamate Transport Proteins and Metabolic Enzymes are Poor Prognostic Factors in Invasive Lobular Carcinoma | |
| GERMIN3在马铃薯中通过调节质膜孔门的开关，参与调控与块茎形成、块茎休眠释放及茎分枝相关的分生组织激活过程。 | Campbell, R. | N/A | GERMIN3 plays a role in plasmodesmatal gating to regulate meristem activation related to tuberisation, tuber dormancy release and stem branching in potato | |
| 比较组织特异性转录组学揭示了两个独立进化的稻属杂草谱系中种子脱粒进化趋同的遗传基础 | Li, X. | N/A | Comparative tissue-specific transcriptomics reveal the genetic bases underlying evolutionary convergence of seed shattering in two independently evolved weedy rice lineages | |
| 鉴定孤儿作物Gynandropsis gynandra中的农艺、营养和叶脉数量性状位点 | Simpson, C. J. C. | N/A | Identifying Agronomic, Nutrition and Leaf Vein Quantitative Trait Loci in the Orphan Crop Gynandropsis gynandra | |
| 碳源-汇反馈对植物生长对环境因素响应的影响 | Friend, A. D. | N/A | Implications of carbon source-sink feedbacks for plant growth responses to environmental factors | |
| 微胶质细胞中肌动蛋白解聚因子ADF/Cfl1的缺乏会降低其迁移能力并损害记忆功能。 | Crux, S. | N/A | Deficiency of actin depolymerizing factors ADF/Cfl1 in microglia decreases motility and impairs memory | |
| 星形胶质细胞衍生的PEA116增强了成年海马神经发生，并赋予了抗压能力 | Carron, C. | N/A | Astrocyte-derived PEA116 increases adult hippocampal neurogenesis and confers stress resilience | |
| 由CD28或4-1BB共刺激驱动的平衡CAR-T细胞代谢与淋巴瘤患者的临床成功相关 | Cook, M. | N/A | A balanced CAR-T cell metabolism driven by CD28 or 4-1BB co-stimulation correlates with clinical success in lymphoma patients | |
| 在囊性纤维化儿童新发感染中分离出的铜绿假单胞菌菌株中，逃避中性粒细胞介导的细菌清除 | Kwong, K. | N/A | Evasion of neutrophil-mediated bacterial clearance in Pseudomonas aeruginosa isolates from new-onset infections in cystic fibrosis children | |
| 古代环境DNA显示，在工业化前的冰岛，人类对海洋生物多样性的影响有限。 | Holman, L. E. | N/A | Ancient environmental DNA indicates limited human impact on marine biodiversity in pre-industrial Iceland | |
| 哺乳动物全血中的激进蛋白质足迹分析 | Tobin, L. | N/A | Radical Protein Footprinting in Mammalian Whole Blood | |
| 在不进行数据整合的情况下，识别独立单细胞研究中的相似群体 | Gonzalez-Velasco, O. | N/A | Identifying similar populations across independent single cell studies without data integration | |
| 质粒接合驱动患者内部质粒多样性 | Grayson, F. | N/A | Plasmid conjugation drives within-patient plasmid diversity | |
| gLinDA：微生物群的全球差异丰度分析 | Fehse, L. | N/A | gLinDA: global differential abundance analysis ofmicrobiomes | |
| stFormer：一种用于空间转录组学的基础模型 | Cao, S. | N/A | stFormer: a foundation model for spatial transcriptomics | |
| 核纤层网络通过被动响应主动或被动的细胞运动来适应限制环境。 | Amiri, S. | N/A | The nuclear lamin network passively responds to both active or passive cell movement through confinements | |
| Pexidartinib联合FLT3定向CAR-巨噬细胞在FLT3-ITD突变急性髓系白血病临床前模型中的治疗研究 | Chen, F. | N/A | Pexidartinib plus FLT3-directed CAR-Macrophage for the treatment of FLT3-ITD-mutated acute myeloid leukemia in preclinical model | |
| CPK3介导的bHLH107胞质-核转位招募HY5以调节Cu2+触发的ACS8上调 | Yu, Y. | N/A | CPK3-mediated cytosolic-nuclear translocation of bHLH107 recruits HY5 to regulate the Cu2+-triggered upregulation of ACS8 | |
| 通过分布式本体感受实现行走和攀爬昆虫的运动原语和身体姿态编码 | van der Veen, T. | N/A | Encoding of movement primitives and body posture through distributed proprioception in walking and climbing insects | |
| FASER：一种用于模拟STED显微镜中点扩散函数畸变的工具 | Bancelin, S. | N/A | FASER: A TOOL TO SIMULATE PSF DISTORTIONS IN STEDMICROSCOPY | |
| 新西兰及其亚南极群岛的禽流感病毒监测在迁徙的海鸟中检测到了H1N9病毒，但未发现2.3.4.4b高致病性H5N1禽流感病毒。 | Waller, S. J. | N/A | Avian influenza virus surveillance across New Zealand and its subantarctic islands detects H1N9 in migratory shorebirds, but not 2.3.4.4b HPAI H5N1 | |
| 枕叶皮层的功能重组导致视觉注意信息在后顶叶皮层中的功能重组。 | Yang, F. | N/A | Pulvinar perturbation causes functional reorganization of visual attentional information in posterior parietal cortex | |
| Hurst指数作为发育中大脑抑制作用的标志 | Nishio, M. | N/A | The Hurst exponent as a marker of inhibition in the developing brain | |
| 杏仁核中间神经元在联想学习和消退中的异质可塑性 | Favila, N. | N/A | Heterogeneous plasticity of amygdala interneurons in associative learning and extinction | |
| # BioRxiv 2024-09-28 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 协调口手食物操作的皮层回路 | An, X. | N/A | A cortical circuit for orchestrating oromanual food manipulation | |
| 针对β冠状病毒的嵌合免疫原的结构预测，以诱导靶向抗体 | Simpson, J. | N/A | Structural prediction of chimeric immunogens to elicit targeted antibodies against betacoronaviruses | |
| 利用分布式光学传感器自动化昆虫生物多样性指标：在美国堪萨斯州农业系统中的评估 | Rydhmer, K. | N/A | Automating an insect biodiversity metric using distributed optical sensors: an evaluation across Kansas, USA cropping systems | |
| 一个标准化、在线交付、临床适用的神经认知评估平台：WebNeuro | Williams, L. M. | N/A | A platform for standardized, online delivered, clinically applicable neurocognitive assessment: WebNeuro | |
| SIMVI揭示了空间组学数据中的内在状态和空间诱导状态 | Dong, M. | N/A | SIMVI reveals intrinsic and spatial-induced states in spatial omics data | |
| 有丝分裂染色质标记控制DNA损伤的不对称分离 | Ferrand, J. | N/A | Mitotic chromatin marking governs asymmetric segregation of DNA damage | |
| 人类骨骼肌纤维异质性超越肌球蛋白重链 | Moreno-Justicia, R. | N/A | Human skeletal muscle fiber heterogeneity beyond myosin heavy chains | |
| NeuroMechFly v2，模拟成年果蝇的具身感觉运动控制 | Wang-Chen, S. | N/A | NeuroMechFly v2, simulating embodied sensorimotor control in adult Drosophila | |
| 解释老年人舌尖现象：大脑功能、结构和灌注对老年人心肺健康的影响 | Rahman, F. | N/A | Explaining tip-of-the-tongue experiences in older adults: contributions of brain function, structure, and perfusion in relation to older adults cardiorespiratory fitness | |
| 果蝇幼虫肠道中病原菌的高效清除需要Duox/TrpA1/Dh31和IMD途径的空间和时间协调。 | Tleiss, F. | N/A | Spatial and temporal coordination of Duox/TrpA1/Dh31 and IMD pathways is required for the efficient elimination of pathogenic bacteria in the intestine of Drosophila larvae | |
| CD44 在空气介导的细胞间信号传导中促进粘附相互作用。 | Bowman, R. L. | N/A | CD44 facilitates adhesive interactions in airineme-mediated intercellular signaling | |
| 视听音乐会表演能够同步观众的心率。 | Czepiel, A. M. | N/A | Audio-visual concert performances synchronize an audience's heart rates | |
| 微眼跳选择性作为对象解码的判别特征 | Nouri, S. | N/A | Microsaccade Selectivity as Discriminative Feature for Object Decoding | |
| 硫酸乙酰肝素结合调控HpARI蛋白家族在体内的半衰期 | Colomb, F. | N/A | Heparan sulphate binding controls in vivo half-life of the HpARI protein family | |
| 哺乳动物腹侧苍白球在单细胞分辨率下的转录组图谱 | Yang, L. | N/A | Transcriptomic landscape of mammalian ventral pallidum at single-cell resolution | |
| 在稀疏数据中对排名列表富集评分进行分析，揭示了算法的权衡 | Wenzel, A. T. | N/A | Profiling ranked list enrichment scoring in sparse data elucidates algorithmic tradeoffs | |
| 毛首鞭形线虫未知的系统发育定位、全基因组组装及基因组范围关联研究：一种引起鞭虫病的新型人感染物种，对阿苯达唑-伊维菌素敏感性较低 | Baer, M. A. | N/A | Phylogenetic placement, whole genome assembly, and genome-wide association study of Trichuris incognita: a novel human-infecting species causing trichuriasis, with low sensitivity to albendazole-ivermectin | |
| 具有保形保证的功能蛋白质挖掘 | Boger, R. S. | N/A | Functional protein mining with conformal guarantees | |
| 沙尘暴驱动的潜在病原体和抗生素抗性基因在东地中海地区的扩散 | Erkorkmaz, B. A. | N/A | Dust storm-driven dispersal of potential pathogens and antibiotic resistance genes in the Eastern Mediterranean | |
| DNA甲基化分析工具中Infinium MethylationEPIC v2.0与v1.0读数差异的影响及对人类群体表观遗传学研究的考量 | Zhuang, B. C. | N/A | Discrepancies in readouts between Infinium MethylationEPIC v2.0 and v1.0 reflected in DNA methylation-based tools: implications and considerations for human population epigenetic studies | |
| 在启动子和增强子内的成簇κB位点之间的协同作用决定了NF-κB RelA的转录特异性，同时还有特定的共因子参与。 | Shahabi, S. | N/A | Cooperativity among clustered κB sites within promoters and enhancers dictates transcriptional specificity of NF-κB RelA along with specific cofactors | |
| 一种能够穿越血脑屏障的神经肽-神经降压素偶联物，在小鼠癫痫持续状态后诱导了具有抗惊厥、神经保护和抗炎特性的药理性低体温。 | Ferhat, L. | N/A | A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice | |
| 急性全身照射对胸腺上皮细胞的第二次影响 | Namiki, K. | N/A | Second impact of an acute total body irradiation on thymic epithelial cells | |
| 掌握神经影像分析中的伪影校正：回顾性方法 | Oliveira, A. | N/A | Mastering Artifact Correction in Neuroimaging Analysis: A Retrospective Approach | |
| 内源性逆转录病毒位点及在日本本土鸡中诱导的基因表达变化 | Ishihara, S. | N/A | Endogenous Retrovirus Loci and Induced Changes in Gene Expression in Japanese Indigenous Chickens | |
| 丰富的活跃社区成员响应温泉光合垫的昼夜周期 | Shelton, A. N. | N/A | Abundant and active community members respond to the diel cycle in hot spring phototrophic mats | |
| 楚科奇海环斑海豹和髯海豹的丰度和分布：未来趋势的参考 | Boveng, P. L. | N/A | Abundance and distribution of ringed and bearded seals in the Chukchi Sea: a reference for future trends | |
| 整合酶复合体亚基12敲除克服了逆转HIV潜伏性的转录阻滞 | Gray, C. N. | N/A | Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal | |
| 像姐妹而非双胞胎——加压素和催产素通过细胞类型特异性表达的催产素受体激活BNST神经元，从而减少焦虑性觉醒。 | Francesconi, W. | N/A | Like sisters but not twins - vasopressin and oxytocin excite BNST neurons via cell type-specific expression of oxytocin receptor to reduce anxious arousal | |
| 在心脏形成过程中，心包膜作为一个独立的结构形成。 | Moran, H. R. | N/A | The pericardium forms as a distinct structure during heart formation | |
| 在加利福尼亚中部城市环境中越冬的穴居猫头鹰（Athene cunicularia hypugaea）到达较晚，离开较早，偏好有遮蔽的微生境，能够忍受雨水，并与多种捕食者竞争。 | Nicolaus, M. A. | N/A | Athene cunicularia hypugaea wintering in a central California urban setting arrive later, leave earlier, prefer sheltered micro-habitat, tolerate rain, and contend with diverse predators | |
| 视网膜母细胞瘤蛋白（Rb）口袋结构域中与癌症相关的错义变异的结构和功能分析 | Castro, A. | N/A | Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein (Rb) pocket domain | |
| 瞬态Notch激活促使多能干细胞衍生的心肌细胞向浦肯野纤维命运转变 | Gonzalez, D. M. | N/A | Transient Notch Activation Converts Pluripotent Stem Cell-Derived Cardiomyocytes towards a Purkinje Fiber Fate | |
| 一种用于筛选异构化介导酶药物靶点的差分离子迁移声波喷射质谱仪系统 | bazargan, s. | N/A | A Differential Ion Mobility Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets | |
| 解码mEos4b的日间成熟过程及工程化快速成熟变体 | Maity, A. | N/A | Decoding mEos4b Day-Long Maturation and Engineering Fast Maturing Variants | |
| 缺血损伤后猪肾脏在常温机械灌注保存结束时，尽管功能未变，但代谢重编程并诱导移植后纤维化：来自肾脏蛋白质组的见解。 | Mulvey, J. F. | N/A | End of preservation normothermic machine perfusion of porcine kidneys after ischaemic injury reprograms metabolism and induces fibrosis after transplant despite unchanged function: insights from the renal proteome. | |
| 系统发育基因组学和代谢工程揭示茄科植物中存在一个保守的甾体生物合成基因簇 | Hakim, S. E. | N/A | Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis | |
| 组织驻留记忆CD4+ T细胞的维持依赖于特定部位的自我更新水平以及来自前体的补充。 | Chandler, J. | N/A | Tissue resident memory CD4+ T cells are sustained by site-specific levels of self-renewal and replacement from precursors | |
| 通过味觉受体检测细菌可启动细胞免疫反应 | Mazariegos, A. N. | N/A | Detection of bacteria through taste receptors primes the cellular immune response | |
| 活体秀丽隐杆线虫的器官特异性亲电应答图谱绘制 | Liu, J. | N/A | Organ-specific electrophile responsivity mappingin live C. elegans | |
| 基于细胞的检测技术评分SARS-CoV-2核衣壳蛋白药物诱导凝聚的比较评估 | Quek, R. T. | N/A | Comparative evaluation of cell-based assay technologies for scoring drug-induced condensation of SARS-CoV-2 nucleocapsid protein | |
| 通过电子断层扫描技术对核糖体数量进行原位定量 | El Hankouri, M. | N/A | In situ quantification of ribosome number by electron tomography | |
| 不同保护制度对西高止山脉木本植物多样性和组成的影响 | Shigwan, B. K. | N/A | Effect of differential protection regimes on the diversity and composition of woody plants in the Western Ghats | |
| 描述与真菌病原体球孢子菌（Coccidioides immitis）相关的土壤微生物群落 | Radosevich, M. T. | N/A | Characterizing the soil microbial community associated with the fungal pathogen Coccidioides immitis | |
| 陆地食草动物通过间接效应推动水生群落的适应性进化 | Schaefer, M. | N/A | Terrestrial herbivory drives adaptive evolution in an aquatic community via indirect effects | |
| 四种酵母物种及其杂交种在极端温度条件下的长期进化潜力 | Pinto, J. | N/A | The long-term evolutionary potential of four yeast species and their hybrids in extreme temperature conditions | |
| 反复的基因渐渗和地理分层塑造了新热带地区的酿酒酵母 | Avelar-Rivas, J. A. | N/A | Recurrent introgression and geographical stratification shape Saccharomyces cerevisiae in the Neotropics | |
| 通过纳米孔长读长测序技术分析天然CpG甲基化，精细定位调控变异 | Tian, Y. | N/A | Fine Mapping Regulatory Variants by Characterizing Native CpG Methylation with Nanopore Long Read Sequencing | |
| 核型I肌球蛋白对生命和基因组组织至关重要 | Peng, A. Y. T. | N/A | Nuclear Type I Myosins are Essential for Life and Genome Organization | |
| Integral-Omics：利用活检组织进行连续提取与代谢组、脂质组、基因组、转录组、全蛋白质组及磷酸化蛋白质组的分析与表征 | Li, W. | N/A | Integral-Omics: serial extraction and profiling of metabolome, lipidome, genome, transcriptome, whole proteome and phosphoproteome using biopsy tissue | |
| 使用ROS/RNS条件蛋白质组学分析参与过氧亚硝酸盐稳态的蛋白质 | Zhu, H. | N/A | Profiling proteins involved in peroxynitrite homeostasis using ROS/RNS conditional proteomics | |
| 生成机器学习用于ADAR底物的精准高效RNA编辑 | Jiang, Y. | N/A | Generative machine learning of ADAR substrates for precise and efficient RNA editing | |
| 统一采样与排序用于蛋白质对接的DFMDock方法 | Chu, L.-S. | N/A | Unified Sampling and Ranking for Protein Docking with DFMDock | |
| CAMDA 2023：在城市微生物群中寻找模式 | Contreras-Peruyero, H. | N/A | CAMDA 2023: finding patterns in urban microbiomes | |
| ConoDL：一种用于快速生成和预测芋螺毒素的深度学习框架 | Guo, M. | N/A | ConoDL: A Deep Learning Framework for Rapid Generation and Prediction of Conotoxins | |
| 通过动力学蒙特卡罗模拟合理化蛋白质-蛋白质相互作用在靶向蛋白质降解中的功能角色 | Su, Z. | N/A | Rationalize the Functional Roles of Protein-Protein Interactions in Targeted Protein Degradation by Kinetic Monte-Carlo Simulations | |
| 肿瘤细胞空间组织通过YAP信号传导指导EGFR/RAS/RAF通路主要治疗抵抗 | Nakagawa, R. | N/A | Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling | |
| 抑制FOXM1与BCL2抑制剂Venetoclax协同作用，通过抑制MYC通路杀死非t(11;14)多发性骨髓瘤细胞。 | Wen, Z. | N/A | Inhibition of FOXM1 synergizes with BCL2 inhibitor Venetoclax in killing non-t(11;14) multiple myeloma cells via repressing MYC pathway | |
| MKK4和MKK7在青光眼相关损伤后控制视网膜神经节细胞体和轴突的退化。 | Marola, O. J. | N/A | MKK4 and MKK7 control degeneration of retinal ganglion cell somas and axons after glaucoma-relevant injury. | |
| ERFVIIs在陆地植物对低氧胁迫响应的进化过程中扮演着氧气感知传感器的角色 | Dalle Carbonare, L. | N/A | The role of ERFVIIs as oxygen-sensing transducers in the evolution of land plant response to hypoxia | |
| 小麦NLR蛋白PM3b定位于内质网-质膜接触位点，并通过其LRR结构域与AVRPM3b2/c2相互作用。 | Isaksson, J. | N/A | The wheat NLR protein PM3b localizes to endoplasmic reticulum-plasma membrane contact sites and interacts with AVRPM3b2/c2 through its LRR domain. | |
| 植物移动域蛋白-DNA基序模块通过对抗Polycomb沉默来稳定基因表达 | Pelissier, T. | N/A | Plant Mobile Domain protein-DNA motif modules counteract Polycomb silencing to stabilize gene expression | |
| 转录记忆介导硫化物胁迫响应的可塑性，以促进单带海神鳗的适应性 | Zhang, W. | N/A | Transcriptional memories mediate the plasticity of sulfide stress responses to enable acclimation in Urechis unicinctus | |
| 一种新型小鼠模型展示了在急性消融成功后中枢神经系统周细胞的在体补充 | Atak, D. | N/A | A Novel Mouse Model Demonstrates In Vivo Replenishment of Central Nervous System Pericytes After Successful Acute Ablation | |
| 生长抑素中间神经元选择初始学习阶段背内侧纹状体的表征 | Rotariu, S. | N/A | Somatostatin interneurons select dorsomedial striatal representations of the initial learning phase | |
| HEXIM1与阿尔茨海默病病理相关，并调控神经元中即刻早期基因的动态变化。 | Htet, M. | N/A | HEXIM1 is correlated with Alzheimer's disease pathology and regulates immediate early gene dynamics in neurons | |
| 利用吉布斯振铃衰减的T1w/T2w-FLAIR髓鞘MRI绘制皮层特定区域边界图 | Autio, J. A. | N/A | Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI | |
| 在患者来源的小鼠模型中，绘制疱疹病毒驱动对卡波西肉瘤细胞微环境和转录组特征的影响 | Li, X. | N/A | Mapping herpesvirus-driven impacts on the cellular milieu and transcriptional profile of Kaposi sarcoma in patient-derived mouse models | |
| 跨完整浮游植物开花周期的微生物宏基因组：在22天内每4小时进行一次高分辨率采样 | Nunn, B. L. | N/A | Microbial Metagenomes Across a Complete Phytoplankton Bloom Cycle:High-Resolution Sampling Every 4 Hours Over 22 Days | |
| 从朋友到敌人，再回到朋友——共生-对抗连续体中的协同进化转变 | Jäger, F. | N/A | From friend to foe and back - Coevolutionary transitions in the mutualism-antagonism continuum | |
| 基因组揭示了禽类吸血蝇（Philornis downsi）在加拉帕戈斯群岛成功入侵的奥秘 | Basnet, A. | N/A | Genomic insights into the successful invasion of the avian vampire fly (Philornis downsi) in the Galapagos Islands | |
| 代谢物对人糖酵解异构酶的弱调节作用：一项筛选研究 | Jonatansdottir, Y. Y. | N/A | Weak Modulation of Human Glycolysis Isomerases by Metabolites: A Screening Study | |
| MetaLab平台支持全面的DDA和DIA元蛋白质组学分析 | Cheng, K. | N/A | MetaLab Platform Enables Comprehensive DDA and DIA Metaproteomics Analysis | |
| 异二硫化物还原酶A（HdrA）的分子进化与功能分化 | Banerjee, M. | N/A | Molecular Evolution and Functional Divergence of Heterodisulfide Reductase A (HdrA) | |
| 酒精对体外原肠胚形成的人类胚胎细胞的转录组、甲基组和代谢组的影响 | Wallen, E. | N/A | Effects of alcohol on the transcriptome, methylome, and metabolome of in vitro gastrulating human embryonic cells | |
| 酶促蛋白质融合，产物收率达100% | Fuchs, A. C. D. | N/A | Enzymatic Protein Fusions with 100% Product Yield | |
| 膜蛋白取向排列诱导的囊泡形状变化 | Feng, M. | N/A | Shape transformation of vesicles induced by orientational arrangement of membrane proteins | |
| 内在无序蛋白质在其构象集合中可以表现出不同的聚合物行为。 | Chakraborty, S. | N/A | Intrinsically disordered proteins can behave as different polymers across their conformational ensemble | |
| 脊髓投射的5-羟色胺能神经元对活跃运动状态的增强作用 | Dasen, J. | N/A | Potentiation of active locomotor state by spinal-projecting serotonergic neurons | |
| 在存在内源性无药物脂质纳米颗粒的情况下，mRNA脂质纳米颗粒的结构表征 | Chen, X. | N/A | Structural Characterization of mRNA Lipid Nanoparticles in the Presence of Intrinsic Drug-free Lipid Nanoparticles | |
| 一个分层贝叶斯模型揭示了随着内感受训练的进行，传入心脏信号的精确度权重增加，同时焦虑感降低。 | Suksasilp, C. | N/A | A hierarchical Bayesian model reveals increased precision weighting for afferent cardiac signals, and reduced anxiety, as a function of interoceptive training | |
| 动作视频游戏玩家的背侧视觉流中的连接性增强 | Cahill, K. | N/A | Connectivity in the Dorsal Visual Stream is Enhanced in Action Video Game Players | |
| Lrrk2和Snca缺陷变异不会改变新生小鼠因神经亲嗜性呼肠孤病毒T3D引起的原发性脑炎的病程。 | Lunn, M. O. | N/A | Variants in Lrrk2 and Snca deficiency do not alter the course of primary encephalitis due to neurotropic reovirus T3D in newborn mice | |
| 桥联脂质转移蛋白3A（BLTP3A）与晚期内吞途径的膜相关，并作为CASM的效应器。 | Hanna, M. G. | N/A | Bridge-like lipid transfer protein 3A (BLTP3A) is associated with membranes of the late endocytic pathway and is an effector of CASM | |
| 我们能从遗留物中发现什么：半水生昆虫蜕皮的DNA代谢条形码研究 | Dworatzek, S. | N/A | What we can find in what's left behind: DNA metabarcoding of semi-aquatic insect exuviae | |
| tRNA池的进化塑造了Saccharomycotina亚门中密码子使用选择的变化 | Cope, A. L. | N/A | Evolution of tRNA pool shapes variation in selection on codon usage across the Saccharomycotina subphylu | |
| 通过X染色体筛选和基因编辑获得的Ogden综合征（NAA10）和NAA15患者来源的诱导多能干细胞系及其同源配对库。 | Wesely, J. | N/A | A repository of Ogden syndrome (NAA10) and NAA15 patient derived iPSC lines and isogenic pairs by X-chromosome screening and genome-editing. | |
| 选择促进线粒体基因组的年龄依赖性退化 | Korotkevich, E. | N/A | Selection promotes age-dependent degeneration of the mitochondrial genome | |
| 量化影响拟南芥基因RNA二级结构的SNP的进化 | Martin, G. T. | N/A | Quantifying evolution of SNPs that affect RNA secondary structure in Arabidopsis thaliana genes | |
| 一种经过计算设计的多样且选择性强的过氧化酶面板，用于萜类化合物的氧功能化 | Munch, J. | N/A | A computationally designed panel of diverse and selective peroxygenases for terpene oxyfunctionalization | |
| 少即是多：慢密码子窗口增强eGFP mRNA对RNA干扰的抵抗力 | Mueller, J. A. | N/A | Less is more: Slow-codon windows enhance eGFP mRNA resilience against RNA interference | |
| 时间分辨的单个葡萄果实转录组：膜运输作为双S型生长的开关 | Savoi, S. | N/A | Time-resolved transcriptomic of single V. vinifera fruits: membrane transports as switches of the double sigmoidal growth | |
| MirGeneDB 3.0：改进的分类学采样，统一命名新发现的保守微RNA家族，以及更新的协方差模型。 | Clarke, A. W. | N/A | MirGeneDB 3.0: Improved taxonomic sampling, uniform nomenclature of novel conserved microRNA families, and updated covariance models. | |
| irCLIP-RNP和Re-CLIP揭示了RNA上动态蛋白质关联的模式 | DUCOLI, L. | N/A | irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein associations on RNA | |
| 人类线粒体ClpP蛋白酶的变构激活机制 | Goncalves, M. M. | N/A | Mechanism of allosteric activation in human mitochondrial ClpP protease | |
| 一种用于胞内检测丙二酰辅酶A的基因编码荧光生物传感器 | Ranzau, B. L. | N/A | A Genetically Encoded Fluorescent Biosensor for Intracellular Measurement of Malonyl-CoA | |
| 酶活性通过调节拥挤环境中的粘度来调控底物扩散 | Bevilacqua, A. | N/A | Enzyme Activity Regulates Substrate Diffusion by Modulating Viscosity in Crowded Milieu | |
| 溶血磷脂酰基团大小、酰基链长度及饱和度对液泡酸化、Ca²⁺转运及融合具有不同的影响。 | Zhang, C. | N/A | Lysophospholipid headgroup size, and acyl chain length and saturation differentially affect vacuole acidification, Ca2+ transport, and fusion | |
| Tris通过线性混合抑制机制抑制GH1 β-葡萄糖苷酶。 | Chagas, R. S. | N/A | Tris inhibits a GH1 β-glucosidase by a linear mixed inhibition mechanism | |
| 利用工程化受体实现合成mRNA的胞外配体响应性翻译调控 | Nakanishi, H. | N/A | Extracellular ligand-responsive translational regulation of synthetic mRNAs using engineered receptors | |
| novoStoic2.0：一个综合框架，用于路径合成、热力学评估和酶选择 | Upadhyay, V. | N/A | novoStoic2.0: An integrated framework for pathway synthesis, thermodynamic evaluation, and enzyme selection | |
| PEG调整使利用丝状支原体受体进行基因组移植成为可能 | Karas, B. J. | N/A | PEG Adjustment Enables Genome Transplantation Using Mycoplasma Mycoides Recipient | |
| AAV血清型转导嗅觉感觉神经元的比较分析 | Belfort, B. D. | N/A | Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons | |
| 一种双调蛋白报告基因小鼠能够实现修复性肺部调节性T细胞的转录和克隆扩增分析。 | Loffredo, L. F. | N/A | An amphiregulin reporter mouse enables transcriptional and clonal expansion analysis of reparative lung Treg cells | |
| 米诺环素增强了未极化巨噬细胞对鲍曼不动杆菌的抗菌活性，同时减少了炎症反应。 | Guerra, A. D. | N/A | Minocycline enhances antimicrobial activity of unpolarized macrophages against Acinetobacter baumannii while reducing the inflammatory response | |
| 克罗恩病最早的病变——口腔溃疡的转录组学特征表明，细菌侵袭性挑战而非整体菌群失调是引发因素。 | Whiley, P. J. | N/A | Transcriptomic signatures of host immune responses in aphthous ulcers, the earliest lesions of Crohn's disease, suggest that a bacterial invasive challenge, rather than global dysbiosis, is the initiating factor. | |
| 基因组导向研究揭示了一组磷脂酶，并突显了沙门氏菌T6SS效应蛋白的多样性。 | Nicastro, G. G. | N/A | Genome-directed study uncovers a family of phospholipases and highlights the diversity of Salmonella T6SS effectors. | |
| Tailocin介导的软腐病欧氏杆菌属细菌间的相互作用 | Borowicz, M. | N/A | Tailocin-mediated interactions in Soft Rot Pectobacteriaceae | |
| 弓形虫速殖子和缓殖子中的运动依赖性过程：相同却又不同 | Kent, R. S. | N/A | Motility-dependent processes in Toxoplasma gondii tachyzoites and bradyzoites: same same but different | |
| 通过深度测序结合平衡核苷酸合成内参法，对低生物量样本抗生素处理后16S基因拷贝进行精确定量 | Chang, C.-C. | N/A | Accurate quantitation of 16S gene copies in low biomass samples post-antibiotic treatment through deep sequencing with a balanced nucleotide synthetic spike-in approach | |
| Ing4缺失增强了多能祖细胞中的造血再生 | Anderson, G. A. | N/A | Loss of Ing4 enhances hematopoietic regeneration in multipotent progenitor cells | |
| 斑马鱼Pol-Theta和人Pol-Theta，具有同源功能的直系同源物 | Thomas, C. | N/A | Zebrafish Pol-Theta and Human Pol-Theta, Orthologues with Homologous Function | |
| 由CRISPR-Cas9 DNA双链断裂引发的兆碱基级杂合性缺失 | Regan, S. B. | N/A | Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks | |
| 强效且选择性的SETDB1共价负变构调节剂可降低细胞中的甲基转移酶活性 | Uguen, M. | N/A | Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells | |
| AAV9介导的针对天然反义转录本的靶向治疗作为一种新型治疗手段用于Dravet综合征 | Antinao Diaz, J. F. | N/A | AAV9-mediated targeting of natural antisense transcript as a novel treatment for Dravet Syndrome | |
| 外膜变化使细菌能够逃避捕食者的进化 | Mridha, S. | N/A | Outer membrane changes enable evolutionary escape from bacterial predation | |
| 鉴定药物/代谢物转运蛋白1作为NF54xCam3.II恶性疟原虫遗传杂交中奎宁抗性的标志物。 | Kanai, M. | N/A | Identification of the drug/metabolite transporter 1 as a marker of quinine resistance in a NF54xCam3.II P. falciparum genetic cross. | |
| 早期内体逃逸可提高所递送酶类货物的催化活性 | Vazquez Maldonado, A. L. | N/A | Earlier endosomal escape improves the catalytic activity of delivered enzyme cargo | |
| 通过在水相中使用角质酶或脂肪酶，实现含有酯键的氧化聚乙烯的高效降解 | Kong, D. | N/A | Efficient degradation of oxidized polyethylene containing ester bonds by cutinase or lipase in aqueous phase | |
| DNA聚合酶Zeta是一种强健的逆转录酶。 | Mayle, R. | N/A | DNA polymerase Zeta is a robust reverse transcriptase | |
| 建模锥虫运动 | Overberg, F. A. | N/A | Modelling trypanosome motility | |
| 秀丽隐杆线虫体细胞中核Argonaute蛋白HRDE-1和NRDE-3的独特调控机制。 | Mendoza, H. | N/A | Distinct regulatory mechanisms by the nuclear Argonautes HRDE-1 and NRDE-3 in the soma of Caenorhabditis elegans. | |
| 2型糖尿病和肥胖症中增加的骨炎症与Wnt信号下调和骨强度降低相关 | Leanza, G. | N/A | Increased bone inflammation in type 2 diabetes and obesity correlates with Wnt signaling downregulation and reduced bone strength | |
| 深度学习有助于植物抗病基因的精准鉴定 | Liu, Z. | N/A | Deep learning facilitates precise identification of disease-resistance genes in plants | |
| 在自然阅读过程中，对正字法和语义旁中央凹信息的快速层次处理 | Wang, L. | N/A | Fast hierarchical processing of orthographic and semantic parafoveal information during natural reading | |
| AIM2对HNSCC发展的影响 | Reinartz, D. M. | N/A | Impact of AIM2 on HNSCC Development | |
| PRMT1 Modulates Alternative Splicing to Enhance HPV18 mRNA Stability and Promote the Establishment of Infection | Williams, D. E. | N/A | PRMT1 Modulates Alternative Splicing to Enhance HPV18 mRNA Stability and Promote the Establishment of Infection | |
| 军团菌自诱导物LAI-1的跨界信号传递涉及抗微生物鸟苷酸结合蛋白GBP。 | Solger, F. | N/A | Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP | |
| 鉴定和表征链球菌性猪病完全毒力所需的ugpE基因 | Yang, Q. | N/A | Identification and characterization of ugpE required for the full virulence of Streptococcus suis | |
| 在易患坏死性小肠结肠炎期间，对产后小肠转录组进行编目 | Oliveria, L. F. S. | N/A | Cataloguing the postnatal small intestinal transcriptome during the period of susceptibility to necrotizing enterocolitis | |
| 嗜热菌G. icigianus细胞对太赫兹辐射的转录组响应 | Bryanskaya, A. | N/A | The transcriptomic response of cells of the thermophilic bacterium G. icigianus to THz irradiation | |
| 社交孤立压力对基于空间学习任务中涉及热威胁的安全学习和防御行为结构的影响 | Villalon, S. A. | N/A | Impact of social isolation stress on safety learning and the structure of defensive behavior during a spatial-based learning task involving thermal threat | |
| # BioRxiv 2024-09-27 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| V1中的离散化表示预测了次优的方向辨别能力 | Corbo, J. | N/A | Discretized representations in V1 predictsuboptimal orientation discrimination | |
| 不同训练方案下小鼠白色和棕色脂肪组织自噬变化的差异 | Tamargo-Gomez, I. | N/A | Autophagy alterations in white and brown adipose tissues of mice exercised under different training protocols | |
| 不同的抑制性神经元以不同的方式塑造听觉皮层中声音强度的神经编码 | Tobin, M. | N/A | Distinct inhibitory neurons differently shape neuronal codes for sound intensity in the auditory cortex | |
| 淀粉样β单体扩散性对老年斑形成的影响 | Kuznetsov, A. V. | N/A | Effect of diffusivity of amyloid beta monomers on the formation of senile plaques | |
| Syngap1通过调节皮层感觉运动动力学促进认知功能 | Vaissiere, T. | N/A | Syngap1 Promotes Cognitive Function through Regulation of Cortical Sensorimotor Dynamics | |
| 通过干预措施使生存曲线变陡，从而压缩发病率 | Yang, Y. | N/A | Compression of morbidity by interventions that steepen the survival curve | |
| 可预测的顺序结构增强了听觉在阈值处的敏感性。 | Marin, N. | N/A | Predictable sequential structure augments auditory sensitivity at threshold | |
| 可预测性和个体阿尔法频率如何塑造记忆：来自事件相关电位研究的启示 | Jano, S. L. | N/A | How predictability and individual alpha frequency shape memory: insights from an event-related potential investigation | |
| 物种内花的进化揭示了在初始传粉者转变过程中适应性行走的趋同现象 | Wenzell, K. E. | N/A | Within-species floral evolution reveals convergence in adaptive walks during incipient pollinator shift | |
| 单细胞多组学和空间图谱揭示了B细胞淋巴瘤的肿瘤内异质性由分化驱动 | Fitzgerald, D. | N/A | A single-cell multi-omic and spatial atlas of B cell lymphomas reveals differentiation drives intratumor heterogeneity | |
| 在群体放电中分离神经振荡的单个周期 | Sabri, E. | N/A | Isolating Single Cycles of Neural Oscillations in Population Spiking | |
| 蓝斑核对前额叶动态的调节及对灵活规则切换的编码 | Nigro, M. | N/A | Locus coeruleus modulation of prefrontal dynamics and encoding of flexible rule switching | |
| 使用新型空间DNA芯片对小鼠肝脏进行2微米分辨率的空间转录组测序 | Ding, X. | N/A | Spatial Transcriptomics Sequencing of Mouse Liver at 2 Micron Resolution Using a Novel Spatial DNA Chip | |
| 全氟和多氟烷基物质在分化神经细胞中的转录组效应 | Running, L. | N/A | Transcriptomics effects of per- and polyfluorinated alkyl substances in differentiated neuronal cells | |
| 周期蛋白依赖性激酶5（Cdk5）的活性受光调节，并调控昼夜节律钟的快速相位转变。 | Brenna, A. | N/A | Cyclin-dependent kinase 5 (Cdk5) activity is modulated by light and gates rapid phase shifts of the circadian clock | |
| 一种用于调控哺乳动物细胞命运的温度诱导蛋白模块 | Benman, W. | N/A | A temperature-inducible protein module for control of mammalian cell fate | |
| 功能性磁共振成像数据集上的伸缩式独立成分分析 | Mirzaeian, S. | N/A | A Telescopic Independent Component Analysis on Functional Magnetic Resonance Imaging Data Set | |
| 揭示白细胞介素-12药代动力学脱敏机制及其后果的数学建模研究 | DeBonis, J. | N/A | Uncovering the Interleukin-12 Pharmacokinetic Desensitization Mechanism and Its Consequences with Mathematical Modeling | |
| 在递归网络中将神经流形与电路结构相连接 | Pezon, L. | N/A | Linking Neural Manifolds to Circuit Structure in Recurrent Networks | |
| 长读长测序与自然历史收藏样本及复杂样本的基因组组装 | Bein, B. | N/A | Long-read sequencing and genome assembly of natural history collection samples and challenging specimens | |
| T细胞极化和NFAT易位依赖于硬度，并且受到Piezo1和Orai1的不同调控。 | Zhao, R. | N/A | T cell polarization and NFAT translocation are stiffness-dependent and are differentially regulated by Piezo1 and Orai1 | |
| 利用生理状况标记揭示自然啮齿动物种群中轻度干旱条件的负面影响 | Keilani, H. S. | N/A | Negative impact of mild arid conditions in natural rodent populations revealed using markers of physiological condition in natura | |
| 蛋白质进化中上位性的突发时间尺度 | Di Bari, L. | N/A | Emergent time scales of epistasis in protein evolution | |
| B细胞α(v)整合素调控流感病毒感染后生发中心来源的肺驻留IgA B细胞反应 | Montiel-Armendariz, A. | N/A | B cell alpha(v) integrin regulates germinal center derived lung-resident IgA B cell responses following influenza virus infection | |
| 为了改进全长核糖体密度预测，通过连接序列和基于图的表示方法 | Nallapareddy, M. V. | N/A | Towards improving full-length ribosome density prediction by bridging sequence and graph-based representations | |
| 蜘蛛社会性的基因组后果及持久性 | Ma, J. | N/A | The genomic consequences and persistence of sociality in spiders | |
| 肾近端小管细胞特异性Megalin缺失不影响小鼠高脂饮食诱导的动脉粥样硬化，但可诱发小管间质性肾炎 | Amioka, N. | N/A | Renal Proximal Tubule Cell-specific Megalin Deletion Does Not Affect Atherosclerosis But Induces Tubulointerstitial Nephritis in Mice Fed Western Diet | |
| 肾近端小管细胞特异性Megalin缺失不影响小鼠高脂饮食诱导的动脉粥样硬化，但可诱发小管间质性肾炎 | Amioka, N. | N/A | Renal Proximal Tubule Cell-specific Megalin Deletion Does Not Affect Atherosclerosis But Induces Tubulointerstitial Nephritis in Mice Fed Western Diet | |
| 结合物理与药物的骨质疏松症治疗方案能够协同增强骨骼反应及局部力学调控 | Schulte, F. A. | N/A | Combined physical and pharmaceutical anabolic osteoporosis therapies synergistically increase bone response and local mechanoregulation | |
| 通过Shielded DNA-PAINT标记协议减少超分辨率DNA-PAINT标记的非特异性结合 | Lucinskaite, E. | N/A | Reduced non-specific binding of super-resolution DNA-PAINT markers by Shielded DNA-PAINT labeling protocols | |
| 一系列增强型AAV和转基因小鼠品系，用于遗传访问皮质细胞类型 | Ben-Simon, Y. | N/A | A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types | |
| 生物医学文献中的生活方式因素：本体论与全面的命名实体识别资源 | Nourani, E. | N/A | Lifestyle factors in the biomedical literature: An ontology and comprehensive resources for named entity recognition | |
| 在休息和手臂运动期间，猕猴的辅助运动区和初级运动皮层的微观钙成像 | Martel, A.-C. | N/A | MICROENDOSCOPIC CALCIUM IMAGING IN SUPPLEMENTARY MOTOR AREA AND PRIMARY MOTOR CORTEX OF RHESUS MACAQUES AT REST AND DURING ARM MOVEMENT | |
| 相同特征，不同基因：阿尔伯塔省三个溪流刺鱼群体的盆骨脊椎缺失 | Mee, J. A. | N/A | Same trait, different genes: pelvic spine loss in three brook stickleback populations in Alberta | |
| 急性全身照射对胸腺上皮细胞的第二次影响 | Namiki, K. | N/A | Second impact of an acute total body irradiation on thymic epithelial cells | |
| 利用OptFed优化生物加工效率：动态非线性建模提升产品与生物量产率 | Schloegel, G. | N/A | Optimizing Bioprocessing Efficiency with OptFed: Dynamic Nonlinear Modeling Improves Product-to-Biomass Yield | |
| 基于纳米孔的分析揭示了科特迪瓦、坦桑尼亚、乌干达和老挝人类感染的鞭虫物种的遗传景观和系统发育位置。 | Rahman, N. | N/A | Nanopore-based analysis unravels the genetic landscape and phylogenetic placement of human-infecting Trichuris species in Cote d'Ivoire, Tanzania, Uganda, and Laos | |
| 氯氰菊酯在小丑鱼变态过程中产生的多层次影响 | Reynaud, M. | N/A | The multi-level effect of chlorpyrifos during clownfish metamorphosis | |
| 鞘氨醇-1-磷酸信号调节穆勒胶质细胞转变为具有神经发生能力、增殖性前体样细胞的能力 | Taylor, O. | N/A | Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells | |
| PTEN的neddylation加剧了乳腺癌中CDK4/6抑制剂的耐药性 | Liu, F. | N/A | PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer | |
| 联会复合体通过湿润作用使减数分裂染色体排列。 | Gordon, S. | N/A | The synaptonemal complex aligns meiotic chromosomes by wetting | |
| 同时对选择和信心程度的深思熟虑的神经基础 | Vivar-Lazo, M. | N/A | Neural basis of concurrent deliberation toward a choice and degree of confidence | |
| 工作记忆处理增强了长期记忆的神经表征 | Sabo, M. | N/A | Working memory processing boosts the neural representation of long-term memories | |
| 乙醇培养下耶氏酵母的生理定量与生物量组成 | Vieira-Lara, M. A. | N/A | Quantitative physiology and biomass composition of Cyberlindnera jadinii in ethanol-grown cultures | |
| 具身视角：角回和楔前叶在自然事件记忆中解码自我身份 | Iriye, H. | N/A | An embodied perspective: angular gyrus and precuneus decode selfhood in memories of naturalistic events | |
| Ki-67和CDK1调控核脂质与有丝分裂染色体的动态结合 | Hu, H.-T. | N/A | Ki-67 and CDK1 Control the Dynamic Association of Nuclear Lipids with Mitotic Chromosomes | |
| 人类重复SRGAP2的斑马鱼模型揭示了其在小胶质细胞和视觉系统发育中的新功能 | Uribe-Salazar, J. M. | N/A | Zebrafish models of human-duplicated SRGAP2 reveal novel functions in microglia and visual system development | |
| 利用直接胶原纤维模型捕捉巩膜各向异性。将微观结构与宏观力学性能联系起来。 | Ji, F. | N/A | Capturing sclera anisotropy using direct collagen fiber models. Linking microstructure to macroscopic mechanical properties. | |
| BirdNET在欧洲城市进行鸟类声学监测方面与专家一样出色。 | Fairbairn, A. J. | N/A | BirdNET is as good as experts for acoustic bird monitoring in a European city | |
| 在青蛙变态发育过程中，脊髓神经元的多样性随着从游泳到四肢运动的转变呈指数级增长。 | Vijatovic, D. | N/A | Spinal neuron diversity scales exponentially with swim-to-limb transformation during frog metamorphosis | |
| 气道应用的IVT mRNA疫苗需要特定的序列设计和高标准的纯化，以去除具有破坏性的双链RNA污染物。 | Zhang, J. | N/A | Airway applied IVT mRNA vaccine needs specific sequence design and high standard purification that removes devastating dsRNA contaminant | |
| 利用动态核极化增强的固态核磁共振技术对天然细菌生物膜进行高灵敏度分析 | Byeon, C.-H. | N/A | High-Sensitivity Analysis of Native Bacterial Biofilms Using Dynamic Nuclear Polarization-Enhanced Solid-State NMR | |
| 平衡生长：GROOT基因在拟南芥中连接植物生物量与温度适应性 | Razzaque, S. | N/A | Balancing Growth: GROOT Genes Link Plant Biomass and Temperature Adaptation in Arabidopsis | |
| 将工程化的人类ARMMs作为治疗性非病毒载体用于体内递送基因编辑有效载荷 | Wang, Q. | N/A | Engineering Human ARMMs as Therapeutic Non-Viral Vehicles for in vivo Delivery of Genome Editing Payloads | |
| LOCAS：基于监督对比学习的mRNA多标签定位 | Abir, A. R. | N/A | LOCAS: Multi-label mRNA Localization with Supervised Contrastive Learning | |
| 酶法合成稀有的ΔUA（1->4）Glc 3, 6, N-硫酸化肝素二糖，对肝素质量控制的意义 | Kandola, T. K. | N/A | Enzymatic access to the rare ΔUA (1->4) Glc 3, 6, N-sulfated heparin disaccharide, implications for heparin quality control | |
| 翻译结果： |
转化性慢性变量应激程序中的样本量报告与合理性：一项系统性综述 | Jordan, C. | PDF | N/A | Reporting and justification of sample size in translational chronic variable stress procedures: A systematic review | | 慢性β淀粉样蛋白寡聚体注射入海马后神经元活动和神经递质释放同时评估的协议 | Herve, V. | PDF | N/A | Protocol for simultaneous evaluation of neuronal activity and neurotransmitter release following chronic amyloid-beta oligomer injections into the hippocampus | | 新生儿缺氧缺血性脑病的鼻内治疗：系统综述、综合分析及对全球护理可及性的影响 | Cavanagh, A. S. | PDF | N/A | Intranasal therapies for neonatal hypoxic-ischemic encephalopathy: Systematic review, synthesis, and implications for global accessibility to care | | 消除常见的神经选择信号并不会使它们成为人工产物。对Frömer等人（2024，《自然·人类行为》）的评论。 | O'Connell, R. G. | PDF | N/A | Regressing Away Common Neural Choice Signals does not make them Artifacts. Comment on Frömer et al (2024, Nature Human Behaviour) | | 消除常见的神经选择信号并不会使它们成为人工产物。对Frömer等人（2024年，《自然·人类行为》）的评论。 | O'Connell, R. G. | PDF | N/A | Regressing Away Common Neural Choice Signals does not make them Artifacts. Comment on Frömer et al (2024, Nature Human Behaviour) | | p97-UBXD8复合体通过抑制过氧化物酶体自噬来维持过氧化物酶体的丰度。 | Montes, I. D. | PDF | N/A | The p97-UBXD8 complex maintains peroxisome abundance by suppressing pexophagy | | 阿维巴坦广谱直接抗菌活性的耐药性迅速出现 | Nägeli, M. | PDF | N/A | Rapid Emergence of Resistance to Broad-Spectrum Direct Antimicrobial Activity of Avibactam | | 菲氏家族成员协同调控军团菌肺炎的毒力 | Andrea, C. | PDF | N/A | Fis family members synergistically control the virulence of Legionella pneumophila | | 全基因组甲基化测序在轻度认知障碍和阿尔茨海默病所致痴呆患者的血液样本中识别认知状态 | Madrid, A. | PDF | N/A | Whole genome methylation sequencing in blood from persons with mild cognitive impairment and dementia due to Alzheimer's disease identifies cognitive status | | HuBMAPR：一个用于HuBMAP数据门户的R客户端 | Hou, C. | PDF | N/A | HuBMAPR: an R Client for the HuBMAP Data Portal | | 用于评估癌症进展和患者病程的组合随机模型 | Wieland, V. | PDF | N/A | Combined Stochastic Models for the Evaluation of Cancer Progression and Patient Trajectories | | 一种通过深度卷积神经网络进行特征选择以编码非线性功能网络连接性的方法及其在精神障碍分类中的应用 | Vo, D. M. | PDF | N/A | A Method of Feature Selection via Deep Convolution Neural Networks For Encoding Nonlinear Functional Network Connectivity and Its Application To The Classification of Mental Disorders | | 创新性的血小板来源外泌体药物递送系统用于治疗角膜新生血管 | Liu, G.-S. | PDF | N/A | Innovative platelet-derived extracellular vesicle drug delivery system for the treatment of corneal neovascularization | | WIMOAD：阿尔茨海默病（AD）诊断的多组学数据加权整合 | Xiao, H. | PDF | N/A | WIMOAD: Weighted Integration of Multi-omics data for Alzheimer's Disease (AD) Diagnosis | | 利用拉曼光谱探索循环外泌体中与乳腺癌相关的生化变化 | Bonizzi, A. | PDF | N/A | Exploring Breast Cancer-Related Biochemical Changes in Circulating Extracellular Vesicles Using Raman Spectroscopy | | 伊米普利酮ONC201或ONC206与替莫唑胺及放疗的三重ITR疗法联合应用，可降低原位野生型IDH胶质母细胞瘤小鼠模型的颅内肿瘤负荷并延长生存期。 | Zhou, L. | PDF | N/A | Combination of Imipridone ONC201 or ONC206 with Temozolomide and Radiotherapy in triple ITR therapy reduces intracranial tumor burden and prolongs survival in an orthotopic wild-type IDH GBM mouse model | | 肿瘤相关巨噬细胞重编程的免疫景观 | Duval, F. | PDF | N/A | The Immune Landscape of Tumor-Associated Macrophage Reprogramming | | 单细胞元分析揭示了T细胞对检查点免疫疗法反应的克隆动力学 | Shorer, O. | PDF | N/A | Single-cell meta-analysis of T cells reveals clonal dynamics of response to checkpoint immunotherapy | | 在部分肌肉去激活期间进行束状伸展，并不会增强人类胫骨前肌随后的神经肌肉输出。 | Raiteri, B. J. | PDF | N/A | Fascicle stretch during partial muscle deactivation does not enhance the human tibialis anterior's subsequent neuromechanical output | | 对全球羽扇豆遗传资源进行遗传和表型特征分析，以开发核心收集品 | Tanwar, U. K. | PDF | N/A | Genetic and phenotypic characterization of global Lupinus albus genetic resources for the development of a CORE collection | | 测定达尔林-锡金喜马拉雅地区特有的多倍体辣椒品种Dalle Khursani中的辣椒素含量及辣度水平 | Ghimiray, T. S. | PDF | N/A | Determination of Capsaicin content and pungency levels in Dalle Khursani accessions, a polyploid Capsicum species specific to Darjeeling-Sikkim Himalaya, India | | 精神分裂症中的自发脑活动与突触密度：一项结合UCB-J PET和fMRI的研究 | Shatalina, E. | PDF | N/A | Spontaneous brain activity and synaptic density in schizophrenia: a combined UCB-J PET and fMRI study | | 健康人体认知功能期间脑激活与线粒体复合物I蛋白水平之间的关系：一项基于BCPP-EF PET和功能性MRI的任务切换研究 | Shatalina, E. | PDF | N/A | The relationship between brain activation and mitochondrial complex I protein levels during cognitive function in healthy humans: an BCPP-EF PET and functional MRI study of task switching | | 竞争下的进化通过减少净能量通量和生长的密度依赖性来增加浮游植物的生产力。 | Briddon, C. L. | PDF | N/A | Evolution under competition increases phytoplankton production by reducing the density-dependence of net energy fluxes and growth | | 用于约会并具有置信度的混合模型 | Darlim, G. | PDF | N/A | Mixture Models for Dating with Confidence | | 独特的可及性与选择性相互作用塑造了结直肠癌腹膜转移的发展过程 | Wassenaar, E. C. | PDF | N/A | A unique interplay of access and selection shapes peritoneal metastasis evolution in colorectal cancer | | 基于表达的选择鉴定出一种对小胶质细胞具有亲和力的AAV衣壳，适用于小鼠的直接和脑脊液途径给药 | Maguire, C. | PDF | N/A | Expression-based selection identifies a microglia-tropic AAV capsid for direct and CSF routes of administration in mice | | 斑马鱼的多行为表型分析揭示了一种新型非联想学习干扰因子，具有环境和人类相关性 | Leuthold, D. | PDF | N/A | Multi-behavioral phenotyping in zebrafish identifies a novel disruptor of non-associative learning with environmental and human relevance | | 线粒体orf125影响马铃薯（+）S. commersonii体细胞杂交的雄性生育力，并参与“Tuberosum”型细胞质雄性不育的启动及普通马铃薯的进化。 | Tamburino, R. | PDF | N/A | The mitochondrial orf125 affects male fertility of Solanum tuberosum (+) S. commersonii somatic hybrids and participates in the onset of ''Tuberosum''-Type CMS and evolution of common potato | | CCR5拮抗剂作为神经保护和增强中风恢复的药物：一项临床前系统综述和荟萃分析 | Sharif, A. | PDF | N/A | CCR5 antagonists as neuroprotective and stroke recovery enhancing agents: a preclinical systematic review and meta-analysis | | 使用静息状态功能性磁共振成像的因果关系映射揭示了精神分裂症患者的高活动性和低连接性 | Tahir, A. | PDF | N/A | Causality Mapping Using Resting-state fMRI Reveals Hyperactivity and Hypoconnectivity in Schizophrenia Patients | | 预测气候变化下雌雄异株植物物种的分布范围变化 | Moutouama, J. K. | PDF | N/A | Forecasting range shifts of a dioecious plant species under climate change | | 三维摄影测量作为一种低成本、便携且非侵入性的方法，用于听觉声学建模。 | Vesterholm, K. K. | PDF | N/A | 3D photogrammetry as a low cost, portable and noninvasive method for acoustic modeling of hearing | | 体外工程化稳定siRNA脂质纳米颗粒：探索可电离脂质浓度对增强制剂稳定性的影响 | Biswal, M. R. | PDF | N/A | In Silico Engineering of Stable siRNA Lipid Nanoparticles: Exploring the Impact of Ionizable Lipid Concentrations for Enhanced Formulation Stability | | TbRGG2 RRM中结合位点灵活性促进RNA扫描的分子动力学模拟研究 | Lemmens, T. | PDF | N/A | How Binding Site Flexibility Promotes RNA Scanning in TbRGG2 RRM: A Molecular Dynamics Simulation Study | | 重复低强度聚焦超声在TgF344-AD大鼠中长期导致小胶质细胞谱系变化 | Abjean, L. | PDF | N/A | Repeated low-intensity focused ultrasound led to microglial profile changes at long term in TgF344-AD rats | | CLYBL通过消除丙二酰辅酶A，避免了甲基丙二酰辅酶A变位酶的抑制和维生素B12的损失。 | Griffith, C. M. | PDF | N/A | CLYBL averts methylmalonyl-CoA mutase inhibition and loss of vitamin B12 by eliminating malyl-CoA | | PfSir2A的生化特性及抑制剂发现——老酶新用 | Donu, D. | PDF | N/A | Biochemical Characterization and Inhibitor Discovery for PfSir2A -- New Tricks for An Old Enzyme | | 丙烯酸改性聚乙二醇微粒用于神经应用中胰岛素样生长因子-1的亲和释放 | Ramos Ferrer, P. | PDF | N/A | Acrylic Acid Modified Poly-ethylene Glycol Microparticles for Affinity-Based release of Insulin-Like Growth Factor-1 in Neural Applications | | AnalyzAIRR：一个用户友好的指导性工作流程，用于AIRR数据分析 | Mhanna, V. | PDF | N/A | AnalyzAIRR: A user-friendly guided workflow for AIRR data analysis | | 可调椭圆柱体用于单DNA分子旋转力学研究 | Hong, Y. | PDF | N/A | Tunable Elliptical Cylinders for Rotational Mechanical Studies of Single DNA Molecules | | 靶向耐药黑色素瘤中异常真核翻译起始因子4E（eIF4E）活性的第二代Cap类似物前药 | Cardenas, E. L. | PDF | N/A | Second-Generation Cap Analogue Prodrugs for Targeting Aberrant Eukaryotic Translation Initiation Factor 4E (eIF4E) Activity in Drug-Resistant Melanoma | | 早晨激活肝胰岛素受体可改善下午的肝糖处理和储存 | Waterman, H. L. | PDF | N/A | Morning Engagement of Hepatic Insulin Receptors Improves Afternoon Hepatic Glucose Disposal and Storage | | 利用快速眼动睡眠期间的靶向记忆再激活来解除情感记忆 | Greco, V. | PDF | N/A | Disarming emotional memories using Targeted Memory Reactivation during Rapid Eye Movement sleep | | 孤立皮层网络中的时间信息编码 | Ferdous, Z. I. | PDF | N/A | Temporal Information Encoding in Isolated Cortical Networks | | 用于光刺激和电生理记录的铸造双色纳米光子神经探针 | Roszko, D. A. | PDF | N/A | Foundry-fabricated dual-color nanophotonic neural probes for photostimulation and electrophysiological recording | | 通过质谱法对衰老小鼠大脑进行多平台脂质分析 | Panda, P. | PDF | N/A | Multiplatform lipid analysis of the brain of aging mice by mass spectrometry | | 持续注意状态的振荡动力学 | Solis-Vivanco, R. | PDF | N/A | Oscillatory dynamics of sustained attention states | | 用于在脑脊液中检测亨廷顿蛋白的挑战与进展：支持相对定量 | Harding, R. J. | PDF | N/A | Challenges and advances for huntingtin detection in cerebrospinal fluid: in support of relative quantification | | 斑马鱼后连合核中视觉运动和地标位置的表征与航向方向一致。 | Lavian, H. | PDF | N/A | The representation of visual motion and landmark position aligns with heading direction in the zebrafish interpeduncular nucleus | | 通过突触蛋白消除的负反馈维持突触可塑性：KIBRA-PKMζ相互作用在长时程增强和记忆中的动态建模 | Shouval, H. | PDF | N/A | Maintenance of synaptic plasticity by negative-feedback of synaptic protein elimination: Dynamic modeling of KIBRA-PKMζ interactions in LTP and memory | | 疟原虫查氏感染后造血干细胞群体的不同反应及恢复动力学。 | Bruno, F. | PDF | N/A | Differential responses and recovery dynamics of HSPC populations following Plasmodium chabaudi infection. | | 巨杉的水分利用效率在山坡生境中高于河岸生境 | Liu, M. | PDF | N/A | Water use efficiency of Cupressus gigantea is higher in mountain slope habitats compared to riverside habitats | | 检测从“狗衰老项目”参与者处收集的饮用水中的重金属含量 | Sexton, C. | PDF | N/A | Testing for heavy metals in drinking water collected from Dog Aging Project participants | | 生态动力学解释了海洋中的模块化反硝化作用 | Sun, X. | PDF | N/A | Ecological dynamics explain modular denitrification in the ocean | | 探索基于环境-代理模型的五大湖管嘴鹬风险评估方法 | Edwards, B. P. | PDF | N/A | Exploring the use of environment-agent-based models for risk assessment of Great Lakes piping plovers | | 滑坡效应：通过气候避难所的视角评估两栖动物灭绝危机 | Andersen, D. K. | PDF | N/A | A slippery slope: assessing the amphibian extinction crisis through the lens of climate refugia | | 博物馆分析揭示了南极冰鱼物种的多样性。 | Garmann-Aarhus, B. | PDF | N/A | Museomics analyses inform about Channichthys icefish species diversity | | 使用基于R的地理信息系统工具定义环境宏基因组学研究的目标人群 | Cruz, D. D. | PDF | N/A | Defining Target Population of Environments to Enviromics Studies Using R-based GIS Tools | | 野化改变小鼠的表观遗传衰老 | Zipple, M. N. | PDF | N/A | Rewilding alters mouse epigenetic aging | | 用于筛选异构化介导酶药物靶点的差分离子迁移声波喷射质谱系统 | bazargan, s. | PDF | N/A | A Differential Ion Mobility Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets | | 工程化活体材料中有序释放微生物 | Kalairaj, M. S. | PDF | N/A | Controlled release of microorganisms from engineered living materials | | 森林中的骷髅：在贝叶斯系统发育树分布上使用基于熵的恶意检测 | Klawitter, J. | PDF | N/A | Skeletons in the Forest: Using Entropy-Based Rogue Detection on Bayesian Phylogenetic Tree Distributions | | 区间删失对生物高通量筛选中数据准确性和机器学习性能的影响 | Doffini, V. | PDF | N/A | Impact of Interval Censoring on Data Accuracy and Machine Learning Performance in Biological High-Throughput Screening | | 利用细胞类型特异性进行单细胞转录组基因集分析 | Frost, H. R. | PDF | N/A | Leveraging cell type-specificity for gene set analysis of single cell transcriptomics | | TMEM16蛋白的稳健脂质翻转需要开放的沟槽和薄膜 | Stephens, C. A. | PDF | N/A | Robust lipid scrambling by TMEM16 proteins requires an open groove and thin membrane | | 亲脂性分子转子用于评估纳米乳液液滴中油核的粘度 | Elhassan, M. | PDF | N/A | Lipophilic molecular rotor to assess the viscosity of oil core in nano-emulsion droplets | | 一种基因编码的荧光传感器能够实现对IDH突变相关肿瘤代谢物D-2-羟基戊二酸的灵敏和特异性检测。 | Choate, K. A. | PDF | N/A | A genetically encoded fluorescent sensor enables sensitive and specific detection of IDH mutant associated oncometabolite D-2-hydroxyglutarate | | Trem2缺乏会减弱瘦小鼠的乳腺癌肿瘤生长，但对肥胖或体重减轻的小鼠则无此效果，并且与克隆T细胞群体的改变相关。 | Pierro, E. W. | PDF | N/A | Trem2 deficiency attenuates breast cancer tumor growth in lean, but not obese or weight loss, mice and is associated with alterations of clonal T cell populations | | 多模态空间分析揭示了输卵管高级别浆液性卵巢癌前体中的免疫抑制和微环境重塑 | Kader, T. | PDF | N/A | Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma | | 体细胞线粒体DNA突变负荷塑造白血病发生中的代谢可塑性 | Li-Harms, X. | PDF | N/A | Somatic mtDNA Mutation Burden Shapes Metabolic Plasticity in Leukemogenesis | | 妊娠期砷暴露改变了母体产后心脏大小，并诱导心肌细胞钙处理失调 | Taube, N. | PDF | N/A | Gestational arsenite exposure alters maternal postpartum heart size and induces Ca2+ handling dysregulation in cardiomyocytes | | 阐明多重反馈回路在调节干细胞决策中的作用 | Shaikh, R. | PDF | N/A | Elucidating the role of multiple feedback loops in regulating stem cell decisions | | 视网膜拓扑编码组织了内部和外部导向脑网络之间的对抗动态。 | Steel, A. | PDF | N/A | Retinotopic coding organizes the opponent dynamic between internally and externally oriented brain networks | | 利用多模态磁共振成像绘制白质通路的总体g-比率图 | Lu, W. D. | PDF | N/A | Mapping the aggregate g-ratio of white matter tracts using multi-modal MRI | | 最大化异构网络中的内存容量 | Zhang, K. | PDF | N/A | Maximizing memory capacity in heterogeneous networks | | JAK抑制剂撤药引发短暂性促炎级联反应：重大心脏不良事件的潜在机制 | Gurevic, I. | PDF | N/A | JAK Inhibitor Withdrawal Causes a Transient Proinflammatory Cascade: A Potential Mechanism for Major Adverse Cardiac Events | | 开发多物种qPCR检测方法用于应激转录谱（STP）芯片，以评估鲑科鱼类对环境变化的适应能力 | Islam, S. S. | PDF | N/A | Development of multi-species qPCR assays for a stress transcriptional profiling (STP) Chip to assess the resilience of salmonids to changing environments | | 环境富集减少adgrl3.1相关焦虑和注意力缺陷，但不影响冲动性 | Fontana, B. D. | PDF | N/A | Environmental Enrichment Reduces adgrl3.1-Related Anxiety and Attention Deficits but Not Impulsivity | | 翻译抑制剂春日霉素、依地因和GE81112在30S起始复合物形成过程中分别作用于不同的步骤。 | Safdari, H. A. | PDF | N/A | The translation inhibitors kasugamycin, edeine and GE81112 target distinct steps during 30S initiation complex formation | | Seed2LP：代谢网络中用于逆生态学应用的种子推断 | Ghassemi Nedjad, C. | PDF | N/A | Seed2LP: seed inference in metabolic networks for reverse ecology applications | | 四环状RNA片段的金属离子感应：非天然金属离子-RNA内壳接触的紧凑中间体的作用 | Habibullah, S. | PDF | N/A | Metal Ion Sensing by Tetraloop-Like RNA Fragment: Role of Compact Intermediates with Non-Native Metal Ion-RNA Inner Shell Contacts | | 前列腺癌骨转移的增强与EphA2非经典信号激活及配体缺乏的骨微环境有关 | Wang, B. | PDF | N/A | Skeletal Metastasis of Prostate Cancer Is Augmented by Activation of EphA2 Noncanonical Signaling and Ligand-Deficient Bone Microenvironment | | 多不饱和脂肪酸及其内源性大麻素相关代谢物在人源TRPV1和TRPA1离子通道上的活性，这些通道在HEK-293细胞中表达。 | Abate, A. A. | PDF | N/A | Polyunsaturated fatty acids and their endocannabinoid-related metabolites activity at human TRPV1 and TRPA1 ion channels expressed in HEK-293 cells. | | 皮层表征漂移的重尾统计特性对稳定下游读数具有优势。 | Micou, C. | PDF | N/A | Heavy-tailed statistics of cortical representational drift are advantageous for stabilised downstream readouts | | 衰老导致的体液稳态系统失调 | Jang, H. | PDF | N/A | Dysregulation of the fluid homeostasis system by aging | | 通过神经对比学习解读睡眠活动 | Chen, Z. | PDF | N/A | Interpreting Sleep Activity Through Neural Contrastive Learning | | 在7T磁共振成像（fMRI）单次扫描中同时测量反相编码EPI：亚毫米级fMRI中几何畸变校正的定量和定性评估 | Yun, S. D. | PDF | N/A | The Simultaneous Measurement of Reversed Phase-Encoding EPI in a Single fMRI Session at 7T: Quantitative and Qualitative Evaluation of Geometric Distortion Correction in Submillimetre fMRI | | 一种关于能量高效神经编码的响应稀疏性和变异性统一理论 | Huang, M. | PDF | N/A | A Unified Theory of Response Sparsity and Variability for Energy-Efficient Neural Coding | | 下丘脑连接性与年轻成人自我评估的攻击性 | Yao, Y. J. | PDF | N/A | Hypothalamic connectivities and self-evaluated aggression in young adults | | 在唐氏综合症模型中，成人补充胆碱可减少共病并改善认知能力 | Tallino, S. | PDF | N/A | Adult choline supplementation in a Down syndrome model reduces co-morbidities and improves cognition | | 执行功能障碍与雄性3xTg阿尔茨海默病模型小鼠海马-前额叶功能连接的改变有关 | Cunliffe, G. | PDF | N/A | Executive dysfunction is associated with altered hippocampal-prefrontal functional connectivity in male 3xTg Alzheimer's model mice | | 视网膜辨别力对自然场景的适应性 | Ding, X. | PDF | N/A | Adaptation of retinal discriminability to natural scenes | | 目标单细胞表达谱分析鉴定出睡眠和代谢状态的整合者 | Shih, M.-F. M. | PDF | N/A | Targeted single cell expression profiling identifies integrators of sleep and metabolic state | | JZL184在体内慢性上调内源性大麻素信号对YAC128亨廷顿病小鼠纹状体突触可塑性和运动学习的影响 | Sepers, M. D. | PDF | N/A | Effect of chronic upregulation of endocannabinoid signaling in vivo with JZL184 on striatal synaptic plasticity and motor learning in YAC128 Huntington disease mice | | PKC eta 和 theta 对信号的不同解释控制着 T 细胞的功能和耗竭。 | Mann, T. H. | PDF | N/A | Different signaling interpretations by PKC eta and theta control T cell function and exhaustion | | 北极极端气候事件的增加与当地生物群落的负面适应性影响有关。 | Lemaire, M. C. | PDF | N/A | Increases in Arctic extreme climatic events are linked to negative fitness effects on the local biota | | 北极红点鲑（Salvelinus alpinus）小型孤立种群中依赖体型的生长率的时空变化 | Mittell, E. | PDF | N/A | Spatiotemporal variation in size-dependent growth rates in small isolated populations of Arctic charr (Salvelinus alpinus) | | 使《昆明-蒙特利尔全球生物多样性框架》的监测框架切实可行。 | Affinito, F. | PDF | N/A | Making the Monitoring Framework of the Kunming-Montreal Global Biodiversity Framework fit for purpose. | | 一个大规模的社区科学花卉颜色数据集揭示了北美红花植物中开花物候的趋同进化 | McKenzie, P. F. | PDF | N/A | A massive community-science flower color dataset reveals convergent evolution of delayed flowering phenology in North American red-flowering plants | | 性选择假说"解释警戒色的起源 | Maisonneuve, L. | PDF | N/A | The 'sexual selection hypothesis' for the origin of aposematism | | 伪毛滴虫属基氏伪毛滴虫的转录组与进化分析，这是一种自由生活的厌氧真核生物 | Abu-Elmakarem, H. | PDF | N/A | Transcriptome and evolutionary analysis of Pseudotrichomonas keilini, a free-living anaerobic eukaryote | | 不像其他针叶树：对英国普通刺柏（Juniperus communis）表型多样性的评估表明，残存种群之间存在遗传隔离和局部适应性。 | Baker, J. P. | PDF | N/A | Not like other conifers: evaluation of phenotypic diversity in British common juniper, Juniperus communis, indicates genetic isolation and local adaptations among remnant populations | | 利用镜像正向遗传学方法鉴定作用于核非编码RNA的人类通路 | Che, R. | PDF | N/A | Identification of Human Pathways Acting on Nuclear Non-Coding RNAs Using the Mirror Forward Genetic Approach | | α-D-甘露糖苷酶抑制剂（-）-苦马豆素的生物合成 | Liu, S. | PDF | N/A | Biosynthesis of the alpha-D-Mannosidase Inhibitor (-)-Swainsonine | | 发现利用SNAr化学的亲电降解剂 | Zhuang, Z. | PDF | N/A | Discovery of electrophilic degraders that exploit SNAr chemistry | | 利用成像质谱技术研究水凝胶扩张的小鼠脑组织中的脂质分布 | Samuel, J. M. | PDF | N/A | Examination of Lipid Distributions in Hydrogel-Expanded Mouse Brain Tissue Using Imaging Mass Spectrometry | | 确定特定肩部功能运动的最佳抗重力辅助水平：一项模拟研究 | Asgari, M. | PDF | N/A | Identifying an optimal anti-gravity assistance level for select functional shoulder movements: A simulation study | | 对牛津纳米孔测序数据集进行RNA修饰的定性回顾 | Pahar, M. | PDF | N/A | A qualitative review of Oxford Nanopore Sequencing datasets for RNA modifications | | FishCODE：一个基于网络的信息平台，用于全面探索鱼类研究中的组学数据 | Li, H. | PDF | N/A | FishCODE: a web-based information platform for comprehensive omics data exploration in fish research | | 多视角综合方法用于填补短链脂肪酸并识别预测血液SCFA的关键因素 | Liu, A. | PDF | N/A | Multi-View Integrative Approach For Imputing Short-Chain Fatty Acids and Identifying Key factors predicting Blood SCFA | | Unipept 6.0：扩展元蛋白质组学分析，支持漏切、半胰蛋白酶和非胰蛋白酶肽 | Vande Moortele, T. | PDF | N/A | Unipept 6.0: Expanding metaproteomics analysis with support for missed cleavages, semi-tryptic and non-tryptic peptides | | 扭转是机械敏感离子通道NOMPC门控的关键 | Duan, J. | PDF | N/A | Twist is the key to the gating of mechanosensitive ion channel NOMPC | | 双峰细胞质量分布将CD8+ T细胞分为两种不同类型，其分化动力学截然不同。 | Yu, J. | PDF | N/A | Bimodal cell mass distribution separates CD8+ T cells into two distinct types with divergentdifferentiation dynamics | | 流明电荷控制β-桶纳米孔中的离子传输 | Mayer, S. F. | PDF | N/A | Lumen charge governs ion transport in β-barrel nanopores | | 弱的、特定的化学相互作用决定了巴纳西在不同细胞环境中的稳定性 | Tahir, U. | PDF | N/A | Weak, specific chemical interactions dictate barnase stability in diverse cellular environments | | ER+乳腺癌中的内分泌持续伴随着氧化磷酸化中的代谢脆弱性 | Tau, S. | PDF | N/A | Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation | | 过度表达白细胞介素6的胰腺癌细胞可引发T细胞介导的肿瘤清除及持久的抗肿瘤免疫反应。 | Arneson-Wissink, P. C. | PDF | N/A | Pancreatic cancer cells overexpressing interleukin 6 induce T-cell-mediated tumor clearance and durable anti-tumor immune response | | 单细胞转录组分析：治疗后和未治疗结直肠癌的潜在耐药机制探究 | Puzanov, G. A. | PDF | N/A | Single-cell Transcriptome Profiling of Post-treatment and Treatment-naive Colorectal Cancer: Insights into Putative Mechanisms of Chemoresistance | | FRMD8调控tmTNF-α在三阴性乳腺癌转移中的加工：对分子通路动态的洞察 | Xu, J. | PDF | N/A | Regulation of tmTNF-α Processing by FRMD8 in Triple-Negative Breast Cancer Metastasis: Insights into Molecular Pathway Dynamics | | MALT1蛋白酶抑制通过逆转肿瘤相关巨噬细胞依赖的免疫抑制，抑制胶质母细胞瘤的进展。 | Hofstatter Azambuja, J. | PDF | N/A | MALT1 protease inhibition restrains glioblastoma progression by reversing tumor-associated macrophage-dependent immunosuppression | | 联合PARP14抑制与PD-1阻断可促进细胞毒性T细胞静息，并调节复发性黑色素瘤中的巨噬细胞极化 | Leshem, R. | PDF | N/A | Combined PARP14 Inhibition and PD-1 Blockade Promotes Cytotoxic T Cell Quiescence and Modulates Macrophage Polarisation in Relapsed Melanoma | | 2023年生长季节澳大利亚燕麦冠锈菌致病性特征分析 | Nguyen, D. T. | PDF | N/A | Characterisation of virulence of Puccinia coronata f. sp. avenae in Australia in the 2023 growing season | | 萌发前温度条件对温带草原物种萌发特性的影响 | Kiss, R. | PDF | N/A | Effect of pre-germination temperature conditions on germination characteristics of temperate grassland species | | 从肿瘤微环境到实体瘤的免疫治疗结果：一种系统理论方法 | Bhattacharya, P. | PDF | N/A | From tumor microenvironment to immuno-therapeutic outcomes for solid tumors: A systems theoretic approach | | 大肠杆菌I类和II类氨酰tRNA合成酶的氨酰化动力学经验模型 | Dykeman, E. C. | PDF | N/A | An empirical model of aminoacylation kinetics for E. coli class I and II aminoacyl tRNA synthetases | | 抑郁症中的异质性食欲模式：营养内感受、奖赏处理与决策制定的计算建模 | Uchida, Y. | PDF | N/A | Heterogeneous Appetite Patterns in Depression: Computational Modeling of Nutritional Interoception, Reward Processing, and Decision-Making | | 超快速多器官蛋白质组学揭示了药物疗效和毒性的组织特异性机制 | Xiong, Y. | PDF | N/A | Ultra-Fast Multi-Organ Proteomics Unveils Tissue-Specific Mechanisms of Drug Efficacy and Toxicity | | 评估高密度表面肌电图描述符对解剖和神经特性随年龄变化的敏感性：一项模拟研究 | Douania, I. | PDF | N/A | Evaluation of HD-sEMG descriptor sensitivity to changes of anatomical and neural properties with aging : A simulation study | | 在任务学习过程中，新皮质各区域之间协调的多层次适应 | Han, S. | PDF | N/A | Coordinated multi-level adaptations across neocortical areas during task learning | | 睡眠调节人脑皮层中的神经时间尺度和时空整合 | Cusinato, R. | PDF | N/A | Sleep modulates neural timescales and spatiotemporal integration in the human cortex | | 解开发放率适应性使得群体编码保持不变 | Brandao, S. C. | PDF | N/A | Undoing of firing rate adaptation enables invariant population codes | | 在假体视觉下最小化物体识别所需的视网膜光幻视数量 | Scialom, E. | PDF | N/A | Minimizing the number of phosphenes required for object recognition under prosthetic vision | | 自然场景中大小恒常性的神经时间进程 | Yeh, L.-C. | PDF | N/A | The neural time course of size constancy in natural scenes | | 结核分枝杆菌MutT1 Nudix水解酶结构域的非典型活性作为蛋白磷酸酶调控核苷二磷酸激酶（NDK）功能 | Emam, E. A. F. | PDF | N/A | An unusual activity of mycobacterial MutT1 Nudix hydrolase domain as a protein phosphatase regulates nucleoside diphosphate kinase (NDK) function | | 小型真核浮游植物在铁限制区域中对碳输出的作用可能远超其规模。 | Meyer, M. G. | PDF | N/A | Small eukaryotic phytoplankton can play an outsized role in carbon export in iron-limited regions | | 来自海洋基因监测计划ARMS-MBON 2018-2020的长期生态研究数据集 | Daraghmeh, N. | PDF | N/A | A long-term ecological research data set from the marine genetic monitoring programme ARMS-MBON 2018-2020 | | 影响南美洲金蝇（双翅目：丽蝇科）种群结构的人口统计和历史过程 | Souza, K. | PDF | N/A | Demographic and Historical Processes Influencing Cochliomyia hominivorax (Diptera: Calliphoridae) Population Structure across South America | | 具有高远端遗传力的转录本介导了遗传因素对复杂代谢性状的影响。 | Tyler, A. L. | PDF | N/A | Transcripts with high distal heritability mediate genetic effects on complex metabolic traits | | 历史性破碎的英国普通刺柏（Juniperus communis L.）种群之间遗传隔离和分化的证据 | Baker, J. P. | PDF | N/A | Evidence of genetic isolation and differentiation among historically fragmented British populations of common juniper, Juniperus communis L. | | 通过比较基因组分析鉴定马拉色菌属物种中假定的端粒酶RNA亚基编码基因 | Sanpedro-Luna, J. A. | PDF | N/A | Identification of the putative gene encoding the RNA subunit of telomerase in Malassezia clade species through comparative genomic analysis | | 结合基因表达和环境因素可提高小麦性状的基因组预测 | Liu, J. | PDF | N/A | Incorporating gene expression and environment improves genomic prediction of wheat traits | | 激光散斑粒度仪（SPARSE）揭示了组织颗粒度的大小分布 | Hajjarian, Z. | PDF | N/A | Laser Speckle Particle Sizer (SPARSE) Informs the Size Distribution of Tissue Granularities | | 重新评估一些结构相似但机制不同的流行CRAC通道抑制剂？ | Gokce, Y. | PDF | N/A | Re-evaluation of some popular CRAC channel inhibitors structurally similar but mechanistically different? | | 小说色彩视觉评估工具：AIM 色彩检测与辨别 | He, J. | PDF | N/A | Novel color vision assessment tool: AIM Color Detection and Discrimination | | RNA结合蛋白敲低后iNeurons中mRNA转运和局部翻译的改变 | Dargan, R. L. | PDF | N/A | Altered mRNA transport and local translation in iNeurons with RNA binding protein knockdown | | 新型神经启发式控制器通过内部模型在较低的肢体任务中推广模块化 | Munoz, D. | PDF | N/A | New neural-inspired controller generalises modularity over lower limb tasks through internal models | | 以乙醇为唯一碳源和能源的条件下，酵母菌的特定生长速率和生长化学计量学 | Warmerdam, M. | PDF | N/A | Specific growth rates and growth stoichiometries of Saccharomycotina yeasts on ethanol as sole carbon and energy substrate | | 肿瘤微环境调控头颈部鳞状细胞癌免疫治疗预后格局：基于计算模型的分析 | Bhattacharya, P. | PDF | N/A | Tumor microenvironment governs the prognostic landscape of immunotherapy for head and neck squamous cell carcinoma: A computational model-guided analysis | | 通过体内超突变进行的氨酰-tRNA合成酶的定向进化 | Furuhata, Y. | PDF | N/A | Directed evolution of aminoacyl-tRNA synthetases through in vivo hypermutation | | 通过工程改造从宏基因组中发现的新型Cas12a同源蛋白，扩展CRISPR工具箱 | Tao, D. | PDF | N/A | Expanding the CRISPR toolbox by engineering Cas12a orthologs of metagenomic discovery | | HU促进高阶染色体组织，并影响肺炎链球菌中的DNA复制速率。 | Mazzuoli, M.-V. | PDF | N/A | HU promotes higher-order chromosome organisation and influences DNA replication rates in Streptococcus pneumoniae | | 多糖生物合成中的耐受机制：对大肠杆菌和福氏志贺菌中十一碳烯醇磷酸回收的启示 | Qin, J. | PDF | N/A | Tolerance Mechanisms in Polysaccharide Biosynthesis: Implications for Undecaprenol Phosphate Recycling in Escherichia coli and Shigella flexneri | | 通过sdiA突变揭示的肺炎克雷伯菌毒力和噬菌体敏感性的调控作用 | Silva-Bea, S. | PDF | N/A | Regulatory effects on virulence and phage susceptibility revealed by sdiA mutation in Klebsiella pneumoniae | | 肠致病性大肠杆菌通过减少牵引力，在富含纤连蛋白的基质上诱导溶组织内阿米巴的Levy样运动 | Guo, Y. | PDF | N/A | Enteropathogenic Escherichia coli induces Entamoeba histolytica Levy-like movement on fibronectin-rich substrate by reducing traction forces | | 关键激酶TgGSK调控弓形虫中心体分裂和内二分裂 | Krueger, A. | PDF | N/A | The essential kinase TgGSK regulates centrosome division and endodyogeny in Toxoplasma gondii | | 霍乱弧菌CsrA通过增加toxR mRNA的稳定性和翻译来控制ToxR的水平。 | Mey, A. R. | PDF | N/A | Vibrio cholerae CsrA controls ToxR levels by increasing the stability and translation of toxR mRNA | | 将荧光蛋白插入MotB的塞域附近可生成功能性定子复合体。 | Gurung, J. P. | PDF | N/A | Insertion of fluorescent proteins near the plug domain of MotB generates functional stator complex. | | 气候波动调节了与病原体动态相关的生态进化过程，并继续加剧番茄细菌性斑点病害的流行。 | Bhandari, R. | PDF | N/A | Climatic fluctuations modulate eco-evolutionary processes associated with pathogen dynamics and continue to fuel bacterial spot epidemics in tomato | | 单细胞变异与细胞系中表型异质性的快速出现——CRISPR-Cas9忠实追随者的一则警示故事。 | Bradley, H. | PDF | N/A | Single cell variation and rapid emergence of phenotypic heterogeneity in cell lines- a cautionary tale for devotees of CRISPR-Cas9. | | 鉴定Saccharolobus islandicus REY15A中Ced和Ups系统的新组分 | Shen, Y. | PDF | N/A | Identification of novel components of the Ced and Ups systems in Saccharolobus islandicus REY15A | | 植物、土壤和商业生物制品中致病性和非致病性木霉菌株的系统发育分析 简称：木霉菌株的系统发育分析 | Pfordt, A. | PDF | N/A | Phylogenetic analysis of pathogenic and non-pathogenic Trichoderma isolates from plants, soil and commercial bio products Short titel: Phylogenetic analysis of pathogenic and non-pathogenic Trichoderma isolates | | 关于鳐类中细菌和寄生虫的元分析综述揭示了研究空白 | Modzelesky, A. | PDF | N/A | Meta-analytic Review of Bacteria and Parasites in Elasmobranchs Provides Insight into Research Gaps | | 阴道毛滴虫中的TvAP65通过与宿主分子相互作用促进HPV感染 | Mei, X. | PDF | N/A | TvAP65 in Trichomonas vaginalis Promotes HPV Infection by Interacting with Host Molecules | | 结核分枝杆菌通过大量改造其脂质组，使用无磷脂质，从而克服磷酸盐饥饿。 | Gray, R. M. | PDF | N/A | Mycobacterium tuberculosis overcomes phosphate starvation by extensively remodelling its lipidome with phosphorus-free lipids | | 硫酸盐还原菌代谢和应激反应中硫氧还蛋白的常见与非常见功能 | Majumder, E. L.- W. | PDF | N/A | The usual and unusual functions of thioredoxins in the metabolism and stress-response of sulfate-reducing bacteria | | 不同个体的人类肠道微生物组样本中，大肠杆菌生态成功的驱动因素各异。 | Boumasmoud, M. | PDF | N/A | Drivers of ecological success for Escherichia coli vary among human gut microbiome samples from different individuals | | 评估金盏花（Tagetes erecta）酒精提取物对临床重要细菌和真菌的抗菌活性。 | Martinez Gonzalez, G. | PDF | N/A | Evaluation of the antimicrobial activity of the alcoholic extract of Tagetes erecta against bacteria and fungi of clinical importance. | | 目前，源自牛的H5N1流感病毒的血凝素基因仍保留着禽流感病毒的表型。 | Yang, J. | PDF | N/A | The Haemagglutinin Gene of Bovine Origin H5N1 Influenza Viruses Currently Retains an Avian Influenza Virus phenotype. | | 评估Ruta chalepensis、Hippocratea excelsa、Litsea glaucescens和Waltheria americana的乙醇提取物对耐甲氧西林金黄色葡萄球菌的抗菌活性 | Martinez Gonzalez, G. | PDF | N/A | Evaluation of antibacterial activity of ethanolic extracts of Ruta chalepensis, Hippocratea excelsa, Litsea glaucescens and Waltheria americana against methicillin-resistant Staphylococcus aureus | | 结构导向设计、合成及表征C22和C32修饰的FK520类似物，其对人致病真菌的活性增强 | Dome, P. A. | PDF | N/A | Structure-guided design, synthesis, and characterization of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi | | 对新型竞争性诱导的链球菌肽聚糖水解酶的自免疫由一种类似Fem转移酶的蛋白质介导 | Marli, M. T. | PDF | N/A | Self-immunity towards a novel competence-induced streptococcal murein hydrolase is mediated by a Fem-transferase-like protein | | 使用高斯混合模型和深度神经网络从异质性冷冻电镜结构中构建分子模型系列 | Chen, M. | PDF | N/A | Building molecular model series from heterogeneous CryoEM structures using Gaussian mixture models and deep neural networks | | snoRNP分子伴侣snR190与Npa1复合体共同形成了一个大分子装配体，该装配体对于60S核糖体亚基的成熟是必需的。 | Hamze, H. | PDF | N/A | The snoRNP chaperone snR190 and the Npa1 complex form a macromomecular assembly required for 60S ribosomal subunit maturation | | 压力易感性的神经蓝图：与压力后果相关的大脑广泛神经活动 | Dirven, B. C. J. | PDF | N/A | The Neural Blueprint of Stress Susceptibility: Brain-wide neuronal activity associated with the consequences of stress | | 内在注意力和外在注意力之间的动态认知差异与抑郁和焦虑障碍有关。 | Oka, T. | PDF | N/A | Dynamic cognitive differences between internal and external attention are associated with depressive and anxiety disorders | | 记忆编码的预测性影响：研究振荡与N400事件相关电位成分 | Jano, S. L. | PDF | N/A | Predictive influences on memory encoding: investigating oscillations and the N400 event-related potential component | | 在记忆形成过程中，内嗅皮层对视觉空间的网格状编码 | Graichen, L. P. | PDF | N/A | Entorhinal grid-like codes for visual space during memory formation | | 丰度测量揭示了人类肠道微生物群中裂解与溶原之间的平衡 | Lopez, J. | PDF | N/A | Abundance measurements reveal the balance between lysis and lysogeny in the human gut microbiome | | 描绘社会行为的图景 | Klibaite, U. | PDF | N/A | Mapping the landscape of social behavior | | 通过调节前额叶皮层的反应性，屏状核增强了神经变异性。 | Atilgan, H. | PDF | N/A | The claustrum enhances neural variability by modulating the responsiveness of the prefrontal cortex | | 在斑胸草雀中，毫秒级别的运动控制先于感觉运动学习 | Pascual, L. M. | PDF | N/A | Millisecond-scale motor control precedes sensorimotor learning in Bengalese finches | | 激活I组代谢型谷氨酸受体对于小鼠海马中异突触性长期增强的预备是必需的。 | Koek, L. A. | PDF | N/A | Activation of group I mGluRs is required for heterosynaptic priming of long-term potentiation in mouse hippocampus | | 浦肯野细胞的内在活动塑造了小脑的发育和功能 | Osorio, C. | PDF | N/A | Purkinje cell intrinsic activity shapes cerebellar development and function | | KCNC1癫痫性脑病新型小鼠模型中快速放电神经元兴奋性受损 | Wengert, E. R. | PDF | N/A | Impaired excitability of fast-spiking neurons in a novel mouse model of KCNC1 epileptic encephalopathy | | 人海马体中的正负视网膜拓扑编码 | Angeli, P. A. | PDF | N/A | Positive and Negative Retinotopic Codes in the Human Hippocampus | | 抑制性可塑性调控的时间精度与效应幅度之间的权衡决定了学习表征的可分离性。 | Rubisch, P. | PDF | N/A | The trade-off between temporal precision and effect amplitude of inhibitory plasticity regulation determines separability of learned representations | | 斯里兰卡蝙蝠中发现致病性钩端螺旋体：潜在的宿主风险首次报告 | Perera, T. | PDF | N/A | First report of pathogenic Leptospira in Sri Lankan bats: A potential reservoir risk | | 在H5N1疫情爆发后，共域海鸟物种之间的无症状感染和同时发生的禽流感病毒抗体流行率存在显著差异。 | Greco, F. | PDF | N/A | Asymptomatic infection and antibody prevalence to co-occurring avian influenza viruses vary substantially between sympatric seabird species following H5N1 outbreaks |
BioRxiv 2024-09-25 Papers
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 从发育到成年，整合的肢骨单细胞图谱 | Herpelinck, T. | N/A | An integrated single-cell atlas of the limb skeleton from development through adulthood | |
| 人类语言中的一个伴随放电回路 | Khalilian-Gourtani, A. | N/A | A Corollary Discharge Circuit in Human Speech | |
| 冬季体重变化在狍（Capreolus capreolus）种群中始终表现出性别特异性。 | Hewison, A. J. M. | N/A | Body mass change over winter is consistently sex-specific across roe deer (Capreolus capreolus) populations | |
| 优化和基准测试基于全基因组关联研究（GWAS）摘要统计的复杂疾病风险评分 | Zhao, Z. | N/A | Optimizing and benchmarking polygenic risk scores with GWAS summary statistics | |
| 依赖于价值的突触可塑性在社交情境中驱动接近和回避行为 | Espinosa, P. | N/A | Valence-dependent synaptic plasticity drives approach and avoidance behavior in social context | |
| 二聚化热力学调控生物相分离 | Dubach, M. | N/A | Dimerization thermodynamics govern biological phase separation | |
| 利用单细胞RNA测序数据对批量组织中细胞丰度进行独立于聚类的估计 | Aubin, R. G. | N/A | Clustering-independent estimation of cell abundances in bulk tissues using single-cell RNA-seq data | |
| HiExM：高通量扩展显微技术实现可扩展的超分辨率成像 | Day, J. H. | N/A | HiExM: high-throughput expansion microscopy enables scalable super-resolution imaging | |
| 急性应激后内啡肽动态变化的高度灵敏体内检测 | Mikati, M. O. | N/A | Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress | |
| 通过单一类别的中间神经元实现的分层行为控制 | Huo, J. | N/A | Hierarchical behavior control by a single class of interneurons | |
| 视神经损伤后，ATF4协调激活轴突再生和神经退行性转录程序 | Somasundaram, P. | N/A | Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by ATF4 following optic nerve injury | |
| 泛组织转录组分析揭示了人类衰老的性别二态性 | Wang, S. | N/A | Pan-tissue Transcriptome Analysis Reveals Sex-dimorphic Human Aging | |
| 使用视觉悬崖和杆下降实验检测小鼠的双眼干扰 | De Jesus-Cortes, H. | N/A | Using the visual cliff and pole descent assays to detect binocular disruption in mice | |
| 老年PANX3敲除小鼠的严重骨关节炎：对新型原发性骨关节炎模型的启示 | Wakefield, B. | N/A | Severe Osteoarthritis in Aged PANX3 Knockout Mice: Implications for a Novel Primary Osteoarthritis Model | |
| 通过相位图和模糊递归图探索大脑功能的非线性动力学 | Li, Q. | N/A | Exploring Nonlinear Dynamics In Brain Functionality Through Phase Portraits And Fuzzy Recurrence Plots | |
| 小脑将输入数据转换成超低分辨率的3D像素。谁知道呢？ | Gilbert, M. | N/A | THE CEREBELLUM CONVERTS INPUT DATA INTO HYPER LOW-RESOLUTION 3-D PIXELS. WHO KNEW? | |
| 超快功率多普勒超声能够纵向追踪血管变化，这些变化与放射治疗后的免疫反应相关。 | Martello, S. E. | N/A | Ultrafast Power Doppler Ultrasound Enables Longitudinal Tracking of Vascular Changes that Correlate with Immune Response After Radiotherapy | |
| 癫痫传播在海马局部卒中期间主要在自由活动的雌性小鼠中触发了对侧病灶的扩散性去极化保护反应。 | Boyce, A. K. | N/A | Seizure propagation triggers a protective contralesional spreading depolarization during focal hippocampal stroke predominantly in freely behaving female mice | |
| 凝聚素在秀丽隐杆线虫中组织围绕活性增强子的三维DNA接触 | Kim, J. | N/A | Cohesin organizes 3D DNA contacts surrounding active enhancers in C. elegans | |
| 元认知体验的时间动态与任务表现中的理性适应相吻合。 | Vermeylen, L. | N/A | The Temporal Dynamics of Metacognitive Experiences Track Rational Adaptations in Task Performance | |
| 迷幻剂的协同、多层次理解：对其药理学、神经影像学和现象学的三次系统综述与元分析 | Shinozuka, K. | N/A | Synergistic, Multi-level Understanding of Psychedelics: Three Systematic Reviews and Meta-analyses of Their Pharmacology, Neuroimaging and Phenomenology | |
| 乳腺导管原位癌的单细胞表达分析揭示了上皮完整性的改变 | Qin, X. | N/A | Single Cell Expression Analysis of Ductal Carcinoma in Situ Identifies Alterations in Epithelial Integrity | |
| 自闭症候选基因rbm-26（RBM26/27）通过调控MALS-1在神经发育过程中保护线粒体功能和轴突免受退化。 | Chowdhury, T. A. | N/A | Autism candidate gene rbm-26(RBM26/27) regulates MALS-1 to protect against mitochondrial dysfunction and axon degeneration during neurodevelopment. | |
| 将人口和扩散的时空变化对集合种群增长率的影响进行分区 | Schreiber, S. | N/A | Partitioning the Impacts of Spatial-Temporal Variation in Demography and Dispersal on Metapopulation Growth Rates | |
| 家麻雀（Passer domesticus）全基因组测序与组装 | Kumar, V. | N/A | Whole Genome Sequencing and Assembly of the House Sparrow, Passer domesticus | |
| 磷酸蛋白质组学分析鉴定REPS1为骨骼肌中胰岛素和运动应答的葡萄糖摄取信号转导器 | Kjaergaard, J. | N/A | Phosphoproteomic Analysis Identifies REPS1 as an Insulin- and Exercise-Responsive Signal Transducer to Glucose Uptake in Skeletal Muscle | |
| 一种重要抗寒油菜种质的全基因组组装与基因组结构 | Wu, Z. | N/A | Genome assembly and genomic architecture of a prominent cold-resistant rapeseed germplasm | |
| 非破坏性X射线断层扫描技术对脑组织超微结构的分析 | Bosch, C. | N/A | Non-destructive X-ray tomography of brain tissue ultrastructure | |
| 使用Recomb-Mix进行快速准确的本地祖先推断 | Wei, Y. | N/A | Fast and accurate local ancestry inference with Recomb-Mix | |
| 肿瘤内氯气二氧化物递送利用其类ROS特性：一种有效癌症治疗的新范式 | Liu, X. | N/A | Intratumoral Delivery of Chlorine Dioxide Exploits its ROS-like Properties: A Novel Paradigm for Effective Cancer Therapy | |
| 高粱基因组-表型关联的GWAS后优先级排序 | Pal, D. | N/A | Post-GWAS Prioritization of Genome-Phenome Associations in Sorghum | |
| 雌激素对奖赏预测误差和强化学习的影响 | Golden, C. E. M. | N/A | Estrogenic control of reward prediction errors and reinforcement learning | |
| Sinorhizobium fredii USDA257 的 VI 型分泌系统对于与大豆 Pekin 品种的成功共生是必需的。 | Reyes-Perez, P. | N/A | The type VI secretion system of Sinorhizobium fredii USDA257 is required for a successful symbiosis with Glycine max cv Pekin | |
| 成年雌性大鼠的嗅鞘细胞是一种混合胶质细胞，能够促进神经修复。 | Phelps, P. E. | N/A | Olfactory ensheathing cells from adult female rats are hybrid glia that promote neural repair | |
| 运动记忆形成的核心：双手适应中的时间泛化 | Howard, I. S. | N/A | Kernels of Motor Memory Formation: Temporal Generalization in Bimanual Adaptation | |
| 脑癌相关结合域突变揭示了CTCF与染色质的关系及其对基因调控的贡献 | Do, C. | N/A | Brain and cancer associated binding domain mutations provide insight into CTCF's relationship with chromatin and its contribution to gene regulation | |
| 在Pol II触发环单倍型内的高阶上位性 | Duan, B. | N/A | Higher-order epistasis within Pol II trigger loop haplotypes | |
| 分布式皮层区域在工作记忆存储中具有不同的表征角色 | Chopurian, V. | N/A | Distinct representational roles of distributed cortical regions for working memory storage | |
| 海洋微生物之间嘌呤和嘧啶交叉喂养的全球生态位划分 | Braakman, R. | N/A | Global niche partitioning of purine and pyrimidine cross-feeding among ocean microbes | |
| 单核多组学揭示了小鼠原始生殖细胞性别决定背后的基因调控网络 | Alexander, A. K. | N/A | Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cells | |
| 通过序列过滤，反复出现的皮质网络编码了自然感官统计数据。 | Deveau, C. | N/A | Recurrent cortical networks encode natural sensory statistics via sequence filtering | |
| 评估预训练的DNA语言模型在调控基因组学中的表征能力 | Tang, Z. | N/A | Evaluating the representational power of pre-trained DNA language models for regulatory genomics | |
| PPFlow：基于扭转流匹配的目标感知肽设计 | Lin, H. | N/A | PPFlow: Target-aware Peptide Design with Torsional Flow Matching | |
| 脂质过氧化与I型干扰素的耦合作用促进了致病性巨噬细胞的激活，导致结核病易感性增加。 | Yabaji, S. M. | N/A | Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis Susceptibility | |
| 从表面和深度电极信号进行主题无关的基于Transformer的神经语音解码 | Chen, J. | N/A | Subject-Agnostic Transformer-Based Neural Speech Decoding from Surface and Depth Electrode Signals | |
| 赋能未来科学家：导师们采用多种策略，引导学生参与专业科学学科素养实践 | Minocha, T. | N/A | Empowering future scientists: Mentors employ various strategies to engage students in professional science disciplinary literacy practices | |
| MOSAIC：一种高效、一步到位的重组工程方法，用于质粒编辑与多样化 | van den Brink, M. | N/A | MOSAIC: a highly efficient, one-step recombineering approach to plasmid editing and diversification | |
| 在开花期间，甘蓝型油菜（Brassica napus）长期受到热应激会负面影响产量，并改变硫代葡萄糖苷和糖类的代谢。 | Kourani, M. | N/A | Prolonged heat stress in Brassica napus during flowering negatively impacts yield and alters glucosinolate and sugars metabolism | |
| Fmo5在杯状细胞成熟和粘液屏障形成中发挥性别特异性作用 | Schaller, M. L. | N/A | Fmo5 plays a sex-specific role in goblet cell maturation and mucus barrier formation | |
| WHIRLY1 调控拟南芥早期幼苗发育中的脂肪族硫代葡萄糖苷生物合成 | Nguyen, L. T. | N/A | WHIRLY1 regulates aliphatic glucosinolate biosynthesis in early seedling development of Arabidopsis | |
| 内在单位：识别系统因果关系的颗粒度。 | Marshall, W. | N/A | Intrinsic Units: Identifying a system's causal grain. | |
| 结肠癌的转移需要Dickkopf-2来生成具有潘氏细胞特性的癌细胞。 | Shin, J. H. | N/A | Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties | |
| 蜘蛛社会性的基因组后果及持久性 | Ma, J. | N/A | The genomic consequences and persistence of sociality in spiders | |
| 品尝硬度？植物肉和动物肉的机械特征 | St. Pierre, S. R. | N/A | Tasting stiffness? The mechanical signature of plant-based and animal meat | |
| 发育中的少突胶质细胞通过调节同步自发活动来调控大脑功能。 | Masumura, R. | N/A | Developmental oligodendrocytes regulate brain function through the mediation of synchronized spontaneous activity | |
| 颈动脉体血管紧张素信号的表观遗传上调增加了血压 | Zhu, F. | N/A | Epigenetic upregulation of carotid body angiotensin signaling increases blood pressure | |
| GeoAB：迈向现实抗体设计与可靠亲和力成熟 | LIN, H. | N/A | GeoAB: Towards Realistic Antibody Design and Reliable Affinity Maturation | |
| 靶向抗癌前乙烯砜碳酸酐酶IX共价抑制剂 | Vaskevicius, A. | N/A | Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX | |
| Oxydifficidin是一种强效的淋病奈瑟菌抗生素，其作用机制涉及DedA辅助摄取和核糖体蛋白RplL的敏感性。 | Kan, J. | N/A | Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA assisted uptake and ribosomal protein RplL sensitivity | |
| 多组学分析揭示了亚麻荠（Camelina sativa）和其他十字花科植物种子中特化代谢物的组成和空间分布的对比情况。 | Barreda, L. | N/A | Multi-omic analyses unveil contrasting composition and spatial distribution of specialized metabolites in seeds of Camelina sativa and other Brassicaceae | |
| 分子和空间转录组学分类中脑多巴胺神经元及其在帕金森病LRRK2G2019S模型中的改变 | Gaertner, Z. | N/A | Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson's disease | |
| IGF2BP3通过靶向FBXO32激活cGMP-PKG信号通路，从而促进胃癌的进展。 | Si, Y. | N/A | IGF2BP3 promotes the progression of gastric cancer by activating cGMP-PKG signaling pathway via targeting FBXO32 | |
| 一种可微分的Gillespie算法，用于模拟化学动力学、参数估计和设计合成生物电路 | Rijal, K. | N/A | A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits | |
| NR2F2在胚胎睾丸中对胎儿间质细胞的发育是必需的。 | Perea-Gomez, A. | N/A | NR2F2 is required in the embryonic testis for Fetal Leydig Cell development | |
| 通过圆二色谱和分子建模解析TMPRSS2信使RNA中的鸟嘌呤四链体结构 | D'Anna, L. | N/A | Resolving the Structure of a Guanine Quadruplex in TMPRSS2 Messenger RNA by Circular Dichroism and Molecular Modeling | |
| 利用大型语言模型解码EB病毒相关疾病的关键靶点和信号通路 | Yu, J. | N/A | Decoding critical targets and signaling pathways in EBV-mediated diseases using large language models | |
| 7K和11K SomaScan血浆蛋白质组学检测的变异性 | Candia, J. | N/A | Variability of 7K and 11K SomaScan plasma proteomics assays | |
| 食欲素神经元群体活动精确地反映了在行为和代谢状态下净身体运动的变化。 | Tesmer, A. L. | N/A | Orexin population activity precisely reflects net body movement across behavioral and metabolic states | |
| 小檗碱是一种新型线粒体钙单向转运体（MCU）抑制剂，能够破坏MCU-EMRE复合体的组装。 | Zhao, H. | N/A | Berberine is a novel mitochondrial calcium uniporter (MCU) inhibitor that disrupts MCU-EMRE assembly | |
| 通过脑转移性黑色素瘤模型揭示的免疫疗法反应的免疫和分子相关性。 | Daugherty-Lopes, A. | N/A | IMMUNE AND MOLECULAR CORRELATES OF RESPONSE TO IMMUNOTHERAPY REVEALED BY BRAIN-METASTATIC MELANOMA MODELS. | |
| 果蝇属物种间雌性攻击性的差异是否与繁殖潜力相关？ | Bath, E. | N/A | Is variation in female aggressiveness across Drosophila species associated with reproductive potential? | |
| 肠道菌群是ALS相关TDP43小鼠性二态性的决定因素 | Beraldi, E. J. | N/A | The gut microbiota is a determinant of sexual dimorphism in ALS-linked TDP43 mice | |
| 红细胞生成素依赖的CD235a-早期红系祖细胞中CD71hiCD105hi表型的获得 | Schippel, N. | N/A | Erythropoietin-dependent Acquisition of CD71hiCD105hi Phenotype within CD235a- Early Erythroid Progenitors | |
| 引入白三叶草（Trifolium repens L.）后抗旱策略的演变 | Hendrickson, B. T. | N/A | Evolution of drought resistance strategies following the introduction of white clover (Trifolium repens L.) | |
| 优化后的扩展显微技术揭示了非洲爪蟾卵提取物中物种特异性的纺锤体微管组织 | Guilloux, G. | N/A | Optimized expansion microscopy reveals species-specific spindle microtubule organization in Xenopus egg extracts | |
| 适应性觉醒调节：通过儿茶酚胺增强觉醒来药理学地改变耶克斯-多德森曲线的峰值 | Beerendonk, L. | N/A | Adaptive arousal regulation: Pharmacologically shifting the peak of the Yerkes-Dodson curve by catecholaminergic enhancement of arousal | |
| 横断面脑龄评估在预测未来脑变化方面存在局限性。 | Korbmacher, M. | N/A | Cross-sectional brain age assessments are limited in predicting future brain change | |
| 识别生长分化因子-15作为代谢功能障碍相关脂肪性肝炎的早期预测生物标志物：基于英国生物样本库蛋白质组数据的嵌套病例对照研究 | Wang, H. | N/A | Identification of Growth Differentiation Factor-15 as An Early Predictive Biomarker for Metabolic Dysfunction-Associated Steatohepatitis: A Nested Case-control Study of UK Biobank Proteomic Data | |
| 肌醇六磷酸（InsP6）通过激活HDAC1/3表观遗传轴来维持肠道屏障功能 | Chatterjee, S. | N/A | Inositol Hexaphosphate (InsP6) Activates the HDAC1/3 Epigenetic Axis to Maintain Intestinal Barrier Function | |
| ArchMap：基于参考的单细胞数据集分析的网络平台 | Lotfollahi, M. | N/A | ArchMap: A web-based platform for reference-based analysis of single-cell datasets | |
| 使用整合和抗CRISPR（IntAC）技术在果蝇细胞中进行高分辨率的全基因组CRISPR敲除筛选 | Viswanatha, R. | N/A | Higher resolution pooled genome-wide CRISPR knockout screening in Drosophila cells using integration and anti-CRISPR (IntAC) | |
| BrainUnit：将物理单位融入高性能AI驱动的科学计算 | Wang, C. | N/A | BrainUnit: Integrating Physical Units into High-Performance AI-Driven Scientific Computing | |
| 亚洲狼的复杂基因组祖先及其在南方的分布，以及推动大陆层面遗传多样性的因素 | Hennelly, L. | N/A | Complex genomic ancestry in southern regions and drivers of continental-level genetic diversity in the wolves of Asia | |
| 造血干细胞来源的脂肪细胞的消融减少了同基因小鼠高级别浆液性癌模型中的肿瘤负担 | Woodruff, E. R. | N/A | Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma | |
| 苜蓿（Medicago truncatula）中的CORYNE基因调控花序分生组织分支、营养信号传递以及丛枝菌根共生关系 | Orosz, J. | N/A | Medicago truncatula CORYNE regulates inflorescence meristem branching, nutrient signaling, and arbuscular mycorrhizal symbiosis | |
| CHAMP1复合物指导异染色质组装并促进同源定向DNA修复 | Li, F. | N/A | CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair | |
| 在单细胞RNA测序中，利用scPCA联合建模细胞异质性和条件效应 | Vohringer, H. S. | N/A | Joint Modeling of Cellular Heterogeneity and Condition Effects with scPCA in Single-Cell RNA-Seq | |
| 超级增强子分析揭示了ThPOK/ZBTB7B，作为CD4+细胞谱系承诺因子，是一个主调控因子，限制乳腺癌细胞呈现腔内非迁移表型。 | Arcuschin, C. D. | N/A | Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4+ cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype | |
| 丙戊酸对髓母细胞瘤中干细胞性和分化调节因子的调控 | Freire, N. H. | N/A | Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma | |
| 脂肪细胞代谢状态调节神经胶质细胞的吞噬功能 | Alassaf, M. | N/A | Adipocyte metabolic state regulates glial phagocytic function | |
| 组成型活性硝酸还原酶的表达增加了尼古丁拟南芥叶片中SARS-CoV-2刺突蛋白的产量，这些叶片原本表现出衰老的特征。 | Hamel, L.-P. | N/A | Expression of a constitutively active nitrate reductase increases SARS-CoV-2 Spike protein production in Nicotiana benthamiana leaves that otherwise show traits of senescence | |
| 一种基于酵母的反向遗传系统，用于生成编码第八个sgRNA的HCoV-OC43报告病毒 | Duguay, B. | N/A | A yeast-based reverse genetics system to generate HCoV-OC43 reporter viruses encoding an eighth sgRNA | |
| 五年间关注的新冠病毒变种中，针对刺突蛋白的中和抗体动态变化揭示了保护免受严重COVID-19的保守表位 | Zayou, L. | N/A | Dynamics of Spike-Specific Neutralizing Antibodies Across Five-Year Emerging SARS-CoV-2 Variants of Concern Reveal Conserved Epitopes that Protect Against Severe COVID-19 | |
| 探索老年人重症COVID-19的生物学机制：来自老年小鼠模型的见解 | Ma, L. | N/A | Exploring the Biological Mechanisms of Severe COVID-19 in the Elderly: Insights from an Aged Mouse Model | |
| 进化独特的N-糖基依赖性蛋白质质量控制系统在新生隐球菌的细胞适应性和细胞外囊泡运输中发挥着关键作用 | Mota, C. | N/A | Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans | |
| 金黄色葡萄球菌酚溶性调节素介导与上呼吸道共生菌的种间竞争 | Huffines, J. T. | N/A | Staphylococcus aureus Phenol-Soluble Modulins Mediate Interspecies Competition with Upper Respiratory Commensal Bacteria | |
| 细菌细胞大小沿着生长曲线在不同营养条件下进行调节 | Nieto, C. | N/A | Bacterial cell size modulation along the growth curve across nutrient conditions | |
| 应用hsp60扩增子测序技术来表征与幼年及成年Euprymna scolopes乌贼相关的微生物群落 | Smith, S. | N/A | Application of hsp60 amplicon sequencing to characterize microbial communities associated with juvenile and adult Euprymna scolopes squid | |
| 对近期出现的猴痘病毒分支的基因组分析揭示了与病毒毒力和传播能力改变相关的基因缺失和单核苷酸多态性。 | Kumar, A. | N/A | Genomic analyses of recently emerging clades of mpox virus reveal gene deletion and single nucleotide polymorphisms that correlate with altered virulence and transmission | |
| 双转座子测序（Dual Tn-seq）用于探测全基因组范围内的遗传相互作用 | Zik, J. J. | N/A | Dual transposon sequencing (Dual Tn-seq) to probe genome-wide genetic interactions | |
| 在模拟生理流动的临界摇动速度下培养疟原虫，揭示了入侵配体的新表型 | Kals, E. | N/A | Growing Malaria Parasites at a Critical Shaking Speed Mimicking Physiological Flow Reveals New Phenotypes for Invasion Ligands | |
| 印度西南海岸孔卡尼人群的母系遗传亲缘关系 | Sequeira, J. J. | N/A | Maternal genetic affinities of Konkani population in the southwest coast of India | |
| 使用ChemNet建模蛋白质-小分子构象集合 | Anishchenko, I. | N/A | Modeling protein-small molecule conformational ensembles with ChemNet | |
| Abdala COVID-19疫苗的结构性和功能性糖基化 | Burnap, S. A. | N/A | Structural and Functional Glycosylation of the Abdala COVID-19 Vaccine | |
| 基于无监督神经网络的膀胱内窥镜图像拼接方法 | Zixing, Y. | N/A | Unsupervised Neural Network-Based Image Stitching Method for Bladder Endoscopy | |
| 高通量细菌聚集分析在液滴中进行 | Saar-Abroi, M. | N/A | High-throughput bacterial aggregation analysis in droplets | |
| 在表达沉默抑制因子P19和冠状病毒样颗粒的烟草本塞姆氏烟叶片中发生的分子变化 | Hamel, L.-P. | N/A | Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus-like particles | |
| 成群的细菌表现出发育阶段转变，以在新区域建立分散的菌落。 | Zdimal, A. M. | N/A | Swarming bacteria exhibit developmental phase transitions to establish scattered colonies in new regions | |
| 通过铜绿假单胞菌对新兴污染物在污水处理厂中的微生物降解 | Lyu, B. | N/A | Microbial Degradation of Contaminants of Emerging Concern by Pseudomonas putida in Wastewater Treatment Plants | |
| 耐药菌携带者口腔微生物群的改变表现出对革兰氏阴性病原体抑制作用的受损 | Zelasko, S. | N/A | Altered oral microbiota of drug-resistant organism carriers exhibit impaired gram-negative pathogen inhibition | |
| 感染性SARS-CoV-2 Omicron XBB.1.41.1谱系在圈养的白尾鹿中通过呼吸道排出，且进化速率增加 | Ferreira, F. C. | N/A | Respiratory shedding of infectious SARS-CoV-2 Omicron XBB.1.41.1 lineage with increased evolutionary rate among captive white-tailed deer | |
| 蛋白质语言模型是否学习了系统发育？ | Tule, S. | N/A | Do Protein Language Models Learn Phylogeny? | |
| 芳香烃受体在平滑肌细胞中的作用可保护免受二恶英诱导的动脉粥样硬化不良重塑的影响 | Qin, G. | N/A | Aryl-hydrocarbon receptor in smooth muscle cells protect against dioxin induced adverse remodeling of atherosclerosis | |
| 赫布诱导在发育中的海马体中，向CA3-CA1突触添加了AMPA不稳定的信号单元。 | Hanse, E. | N/A | Hebbian induction adds AMPA-labile signaling units to CA3-CA1 synapses in the developing hippocampus | |
| 一种稳健且高效的转化方法，适用于最小的支原体细胞 | Mizutani, M. | N/A | Robust and highly efficient transformation method for a minimal Mycoplasma cell | |
| prfB中程序性核糖体移码的进化与功能意义 | Prince, C. R. | N/A | The evolution and functional significance of the programmed ribosomal frameshift in prfB | |
| 囊性纤维化痰液中金黄色葡萄球菌生长的遗传需求和营养可用性分析 | Shull, L. M. | N/A | Analysis of genetic requirements and nutrient availability for Staphylococcus aureus growth in cystic fibrosis sputum | |
| AQP1- 与棕色脂肪组织沉默相关的调节因子 | Cheng, C. | N/A | AQP1- A regulatory factor associated with brown adipose tissue silencing | |
| 参与蛋白质折叠和染色质组织的基因能够缓冲遗传变异。 | Frickel, J. | N/A | Genes involved in protein folding and chromatin organization buffer genetic variation | |
| 尼安德特人衍生的变异影响人类疾病位点的颅面增强子活性 | Uttley, K. | N/A | Neanderthal-derived variants shape craniofacial enhancer activity at a human disease locus | |
| 巨噬细胞在吞噬作用后重新部署功能性癌细胞表面蛋白 | Volk, R. F. | N/A | Macrophages redeploy functional cancer cell surface proteins following phagocytosis | |
| 适应高压环境：从一种进化出的耐压性增强的大肠杆菌菌株的基因组中获得的见解 | Allemann, M. N. | N/A | Adaptation to high pressure; insights from the genome of an evolved Escherichia coli strain with increased piezotolerance | |
| 组蛋白去甲基化酶KDM5A和KDM5B通过抑制内源性逆转录病毒元素的转录来调节免疫反应。 | Chen, H. | N/A | Histone demethylase enzymes KDM5A and KDM5B modulate immune response by suppressing transcription of endogenous retroviral elements | |
| 几乎完整的人类基因组中复杂的基因变异 | Logsdon, G. A. | N/A | Complex genetic variation in nearly complete human genomes | |
| 微胶质细胞与胶质母细胞瘤在远端浸润区的相互作用动力学 | Nebeling, F. C. | N/A | Dynamics of microglia-glioblastoma crosstalk at the far infiltration zone | |
| 益生菌声学生物传感器用于非侵入性肠道炎症成像 | Buss, M. T. | N/A | Probiotic acoustic biosensors for noninvasive imaging of gut inflammation | |
| MedGraphNet：利用多关系图神经网络和文本知识进行生物医学预测 | Macaulay, O. | N/A | MedGraphNet: Leveraging Multi-Relational Graph Neural Networks and Text Knowledge for Biomedical Predictions | |
| 吐根生物碱生物合成的独立进化 | Colinas, M. | N/A | Independent evolution of ipecac alkaloid biosynthesis | |
| 从同质性到异质性：优化基因调控的随机模拟 | Chae, S. J. | N/A | From Homogeneity to Heterogeneity: Refining Stochastic Simulations of Gene Regulation | |
| 神经成熟提供了表征的稳定性以及理解复杂概念的解决方案 | Watanabe, H. | N/A | Neural Maturation Provides the Stability of Representation and the Solution for Understanding Complex Concepts | |
| 对小鼠端脑神经上皮顶端核迁移的定量整体活体成像分析 | Shimamura, T. | N/A | Quantitative in toto live imaging analysis of apical nuclear migration in the mouse telencephalic neuroepithelium | |
| Caveolin-1调控Ewing肉瘤中依赖于环境的信号传导和生存。 | Segal, D. | N/A | Caveolin-1 regulates context-dependent signaling and survival in Ewing Sarcoma. | |
| GDF3通过改变染色质可及性，促进脂肪组织巨噬细胞介导的炎症反应，这一过程在衰老期间尤为显著。 | Jang, I. H. | N/A | GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility during aging | |
| ECOLOPES植物模型：一种高分辨率模型，用于模拟城市及其他人为主导和管理环境中的植物群落动态 | Joschinski, J. | N/A | The ECOLOPES PLANT MODEL : a high-resolution model to simulate plant community dynamics in cities and other human-dominated and managed environments | |
| 易受伤害的驯鹿和驼鹿种群对山松甲虫爆发和管理的反应截然不同。 | Griffin, L. L. | N/A | Vulnerable caribou and moose populations display contrasting responses to mountain pine beetle outbreaks and management. | |
| 古代多倍体化和染色体丢失率低解释了同型孢子蕨类植物高染色体数的原因。 | Li, Z. | N/A | Ancient polyploidy and low rate of chromosome loss explain the high chromosome numbers of homosporous ferns | |
| 资源呈现方式决定了酵母的基因和表型适应性。 | Ahlawat, N. | N/A | Resource presentation dictates genetic and phenotypic adaptation in yeast. | |
| 大规模死亡事件后珊瑚适应与恢复的基因组特征 | Fifer, J. E. | N/A | Genomic signatures of coral adaptation and recovery following a mass mortality event | |
| 蚊子物种Culex tarsalis的气候适应与遗传分化 | Liao, Y. | N/A | Climate Adaptation and Genetic Differentiation in the Mosquito Species Culex tarsalis | |
| 体外分析T7 RNA聚合酶生物传感器竞争性抑制模型的研究 | Delaney, R. M. | N/A | in vitro analysis of a competitive inhibition model for T7 RNA polymerase biosensors | |
| INSPIRE：可解释、灵活且具有空间感知能力的多种来源空间转录组数据集整合 | Zhao, J. | N/A | INSPIRE: interpretable, flexible and spatially-aware integration of multiple spatial transcriptomics datasets from diverse sources | |
| 使用INMTD进行个体聚类：一种集成组学和影像数据的新型多功能多视角嵌入框架 | Li, Z. | N/A | Clustering individuals using INMTD: a novel versatile multi-view embedding framework integrating omics and imaging data | |
| RGD-含配体对整合素αVβ3分子识别的结构见解：特异性决定环（SDL）的作用 | Mariasoosai, C. | N/A | Structural insights into the molecular recognition of integrin αVβ3 by RGD-containing ligands: The role of the specificity-determining loop (SDL) | |
| 类A G蛋白偶联受体（FPR2/ALX）中resolvins D1（RvD1）的进入和结合的结构基础 | Mun, B. | N/A | Structural basis for the access and binding of resolvin D1 (RvD1) to formyl peptide receptor 2 (FPR2/ALX), a class A GPCR | |
| 胞外相分离介导了甲状腺球蛋白在甲状腺滤泡腔内的储存与释放 | Knowles, T. | N/A | Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen | |
| IGF2BP3通过依赖M6A、独立于帽结构的c-Met翻译促进自噬介导的TNBC转移 | Wang, Z. | N/A | IGF2BP3 Promotes Autophagy-Mediated TNBC Metastasis via M6A-Dependent, Cap-Independent c-Met Translation | |
| 一个优化的高通量批量RNA-Seq反卷积流程展示了肥胖和体重减轻对人类脂肪组织细胞组成的影响 | Ahn, C. | N/A | An optimized pipeline for high-throughput bulk RNA-Seq deconvolution illustrates the impact of obesity and weight loss on cell composition of human adipose tissue | |
| 在小鼠骨骼肌中可诱导且可逆的SOD2敲低导致丙酮酸氧化受损和代谢灵活性降低 | Ostrom, E. L. | N/A | Inducible and reversible SOD2 knockdown in mouse skeletal muscle drives impaired pyruvate oxidation and reduced metabolic flexibility | |
| 高粱、水稻和玉米中GRAS家族转录因子结合行为的比较研究 | Gladman, N. P. | N/A | GRAS Family Transcription Factor Binding Behaviors in Sorghum bicolor, Oyrza, and Maize | |
| 靶向CCRL2增强结核病小鼠模型的治疗效果 | Wang, T. | N/A | Targeting CCRL2 enhances therapeutic outcomes in a tuberculosis mouse model | |
| 穿孔素-2在宿主防御烟曲霉和白色念珠菌方面并非必需。 | Aufiero, M. | N/A | Perforin-2 is dispensable for host defense against Aspergillus fumigatus and Candida albicans | |
| 从波兰患有牛呼吸道疾病症状的奶牛犊中分离出的多杀性巴氏杆菌和溶血性曼海姆菌的抗菌药物抗性及毒力相关基因 | Lachowicz-Wolak, A. | N/A | Antimicrobial Resistance and Virulence-Associated Genes of Pasteurella multocida and Mannheimia haemolytica Isolated from Polish Dairy Calves with Symptoms of Bovine Respiratory Disease | |
| 对日本青鳉在不同大小片段中的环境RNA进行全面测序，并与皮肤RNA进行比较 | Hiki, K. | N/A | Comprehensive Sequencing of Environmental RNA from Japanese Medaka at Various Size Fractions and Comparison with Skin RNA | |
| 对日本青鳉不同大小片段的环境RNA进行全面测序，并与皮肤RNA进行比较 | Hiki, K. | N/A | Comprehensive Sequencing of Environmental RNA from Japanese Medaka at Various Size Fractions and Comparison with Skin RNA | |
| 景观分区的模式表明，几内亚狒狒（Papio papio）群体之间存在较低的资源竞争水平。 | Ohrndorf, L. | N/A | Patterns of landscape partitioning indicate low levels of resource competition among neighbouring Guinea baboon(Papio papio) parties | |
| 在个人基因组和转录组数据上微调序列到表达模型 | Rastogi, R. | N/A | Fine-tuning sequence-to-expression models onpersonal genome and transcriptome data | |
| ELLA：在高分辨率空间转录组学中建模细胞内基因表达的亚细胞空间变异。 | Wang, J. | N/A | ELLA: Modeling Subcellular Spatial Variation of Gene Expression within Cells in High-Resolution Spatial Transcriptomics. | |
| 机器人可见光光学相干断层扫描技术可视化了段状施莱姆管的解剖结构及段状毛果芸香碱反应 | Fang, R. | N/A | Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemms Canal Anatomy and Segmental Pilocarpine Response | |
| 海月：基于语言模型的分子运动预测 | Lombard, V. | N/A | SeaMoon: Prediction of molecular motions based on language models | |
| 评估帕金森病中α-突触核蛋白寡聚体累积神经毒性的标准 | Kuznetsov, A. V. | N/A | Criterion for assessing accumulated neurotoxicity of alpha-synuclein oligomers in Parkinson's disease | |
| 使用靶向CRISPR基因编辑技术生成对PARPi敏感的纯合BRCA1甲基化OVCAR8细胞系 | Nesic, K. | N/A | Generation of a PARPi-sensitive homozygous BRCA1-methylated OVCAR8 cell line using targeted CRISPR gene editing | |
| 利用转录调控网络预测结核分枝杆菌中的细菌适应性：可解释的机器学习方法 | Bustad, E. | N/A | Predicting bacterial fitness in Mycobacterium tuberculosis with transcriptional regulatory network-informed interpretable machine learning | |
| RNA-DCGen：基于LLM-Attack的双重约束RNA序列生成 | Shahgir, H. S. | N/A | RNA-DCGen: Dual Constrained RNA Sequence Generation with LLM-Attack | |
| 妊娠期SARS-CoV-2感染的胎盘中显示出氧化应激和DNA损伤的焦点。 | Nobrega, G. | N/A | Placentas from SARS-CoV-2 infection during pregnancy exhibit foci of oxidative stress and DNA damage | |
| 对来自欧洲和南美洲的四种羊口疮病毒株的全基因组分析。 | Cacciabue, M. | N/A | The whole genome analysis of four Orf virus strains from Europe and South America. | |
| 新型高质量阿米巴虫基因组揭示巨型病毒与其宿主之间普遍存在的密码子使用不匹配现象 | Willemsen, A. | N/A | Novel high-quality amoeba genomes reveal widespread codon usage mismatch between giant viruses and their hosts | |
| 果蝇X连锁肾上腺脑白质营养不良ABCD1基因的遗传分析揭示了其在过氧化物酶体动力学中的作用 | Manor, J. | N/A | Genetic analysis of the X-linked Adrenoleukodystrophy ABCD1 gene in Drosophila uncovers a role in Peroxisomal dynamics | |
| 在基因组学时代计算和解释FST | de Jong, M. J. | N/A | Calculating and interpreting FST in the genomics era | |
| 从与果蝇相关的三种螺原体（Citri 支系）菌株的草图基因组组装中推断出其毒素库多样但代谢能力有限 | Ramirez, P. | N/A | Diverse toxin repertoire but limited metabolic capacities inferred from the draft genome assemblies of three Spiroplasma (Citri clade) strains associated with Drosophila | |
| 利用界面张力分选法（SIFT）逐步分离多种代谢细胞群体 | Shulman, M. | N/A | Stepwise Isolation of Diverse Metabolic Cell Populations Using Sorting by Interfacial Tension (SIFT) | |
| p53motifDB：整合基因组信息与肿瘤抑制因子p53结合基序 | Baniulyte, G. | N/A | p53motifDB: integration of genomic information and tumor suppressor p53 binding motifs | |
| SARS CoV 2核衣壳蛋白的二聚化结构域在单体状态下部分无序，并形成高亲和力的动态复合物。 | Cubuk, J. | N/A | The dimerization domain of SARS CoV 2 Nucleocapsid protein is partially disordered as a monomer and forms a high affinity dynamic complex. | |
| 铜绿假单胞菌外膜胞外多糖转运蛋白PelBC的组装与动力学 | Benedens, M. | N/A | Assembly and dynamics of the outer membrane exopolysaccharide transporter PelBC of Pseudomonas aeruginosa | |
| SUMO2抑制逆转了由滑膜肉瘤融合癌蛋白驱动的异常表观遗传重编程，并损害了肉瘤发生 | Iyer, R. | N/A | SUMO2 Inhibition Reverses Aberrant Epigenetic Rewiring Driven by Synovial Sarcoma Fusion Oncoproteins and Impairs Sarcomagenesis | |
| 利用深度学习技术对化石禾本科花粉的超分辨率图像进行分析，重构古草原的多样性动态变化 | Adaime, M.-E. | N/A | Reconstructing the diversity dynamics of paleo-grasslands using deep learning on superresolution images of fossil Poaceae pollen | |
| XXX和XXY三倍体大麻的性表达、生物量、大麻素含量及种子产量的比较 | Paul, N. | N/A | A Comparison of the Sexual Expression, Biomass, Cannabinoid Content, and Seed Production in XXX and XXY Triploid Cannabis | |
| 用于测试抗SARS-CoV-2炎症化合物的炎症细胞平台（INCEPLAT） | LOPEZ-AYLLON, B. D. | N/A | Inflammation cellular platform (INCEPLAT) for testing anti-inflammatory compounds for SARS-CoV-2 | |
| SARS-CoV-2 ORF3a蛋白损害合胞体滋养层细胞的成熟，改变ZO-1的定位，并在滋养层细胞和三维类器官中改变自噬途径 | Kumar, D. | N/A | SARS-CoV-2 ORF3a Protein Impairs Syncytiotrophoblast Maturation, Alters ZO-1 Localization, and Shifts Autophagic Pathways in Trophoblast Cells and 3D Organoids | |
| 由丙酮酸脱氢酶驱动的碳水化合物燃料的线粒体氧化作用显著增强了老年和老年期肠干细胞的干性。 | Ahmed, S. | N/A | Mitochondrial oxidation of the carbohydrate fuel driven by pyruvate dehydrogenase robustly enhances stemness of older and geriatric Intestinal Stem Cells | |
| GATA2缺乏综合征中的血液学表型源于继发性损伤和对增殖的适应不良。 | Fernandez-Orth, J. | N/A | Hematological phenotypes in GATA2 deficiency syndrome arise from secondary injuries and maladaptation to proliferation | |
| 感染负荷的均值和方差揭示了未被察觉的宿主进化 | Walsman, J. C. | N/A | The mean and variance of infection load reveal unseen host evolution | |
| 昆虫神经性别决定系统的演化：蟋蟀中的doublesex同源基因作为X连锁的雄性化因子，调节形态学上的性别二型性，但不影响行为上的性别二型性。 | Watanabe, T. | N/A | Evolution of the neural sex-determination system in insects: The doublesex homolog in crickets functions as an X-linked masculinizing factor to regulate morphological but not behavioral sexual dimorphism | |
| 钙黏蛋白16通过斯塔尼乌斯内分泌小体促进感觉门控 | Schloss, S. S. | N/A | Cadherin 16 promotes sensory gating via the endocrine corpuscles of Stannius | |
| 基于长读长全基因组测序的单细胞同时单倍型分型与非整倍体分析 | Zhao, Y. | N/A | Long-read whole-genome sequencing-based concurrent haplotyping and aneuploidy profiling of single cells | |
| 伤口闭合过程中EDA纤连蛋白微结构与YAP易位的关系 | Patten, J. | N/A | EDA Fibronectin Microarchitecture and YAP Translocation During Wound Closure | |
| 不同前列腺癌模型中的氧化磷酸化抑制及其与雄激素受体信号的相互作用 | Sakellakis, M. | N/A | Oxidative Phosphorylation Inhibition in Different Prostate Cancer Models and the Interplay with Androgen Receptor Signaling | |
| 高维中介分析与网络中介：应用于儿童急性淋巴细胞白血病 | Wang, J. | N/A | High-Dimensional Mediation Analysis with Network Mediators: Applications to Pediatric Acute Lymphoblastic Leukemia. | |
| 视觉雪花症患者的方向运动敏感性受到拖尾型视物残留存在的影响而发生调节。 | Obukhova, T. S. | N/A | Directional motion sensitivity in people with Visual Snow Syndrome is modulated by the presence of trailing-type palinopsia | |
| 自闭症谱系障碍中社会视觉通路的破坏 | Li, C. | N/A | Disruption of the Social Visual Pathway in Autism Spectrum Disorder | |
| 自身抗体针对干扰素在慢性乙型肝炎病毒感染者中较为常见，并与聚乙二醇干扰素治疗无应答相关。 | Fink, D. L. | N/A | Auto-antibodies against interferons are common in people living with chronic hepatitis B virus infection and associate with PegIFN non-response | |
| 通用感受系统作为金黄色葡萄球菌转录组活动的新型调节器 | Tetz, G. | N/A | Universal Receptive System as a novel regulator of transcriptomic activity of Staphylococcus aureus | |
| 阿尔伯塔首次记录库蚊（双翅目：蚊科）：加拿大西部省份分布范围扩大及生态型模式 | Soghigian, J. | N/A | First record of Culex pipiens (Diptera: Culicidae) in Alberta: Expanding distributions and ecotype patterns in a western Canadian province | |
| 隐形人群：探究遥感数据集如何揭示森林周边人口的分布情况 | Rakotoarisoa, M. | N/A | Invisible people: Exploring how well remote-sensed datasets reveal the distribution of forest-proximate populations | |
| 萤火虫Photinus pyralis中色素在光色变化中的作用 | Popecki, M. S. | N/A | The role of pigments in light color variation of the firefly Photinus pyralis | |
| 通过ATAC-seq定义的足迹QTLs鉴定与转录因子结合相关的非编码变异的特征，在肝脏中的研究 | Dudek, M. F. | N/A | Characterization of non-coding variants associated with transcription factor binding through ATAC-seq-defined footprint QTLs in liver | |
| 物种间连锁不平衡图谱 | Zhu, T.-N. | N/A | An Atlas of Linkage Disequilibrium Across Species | |
| Sost mRNA和Sclerostin在体内机械负荷下的三维空间分布 | Meslier, Q. A. | N/A | 3D spatial distribution of Sost mRNA and Sclerostin expression in response to in vivo mechanical loading | |
| 发芽糙米研究：进展、热点与趋势的文献计量分析 | Zhang, W. | N/A | Germinated brown rice research: bibliometric analysis of progress, hotspots and trends | |
| 利用神经网络校正FoldX自由能估算 | Barnes, J. E. | N/A | Leveraging neural networks to correct FoldX free energy estimates | |
| nSMase2介导的外泌体分泌塑造了肿瘤微环境，以免疫学方式支持胰腺癌 | Hendley, A. M. | N/A | nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer | |
| 糖饮食对蚊子湿度偏好、存活率及宿主降落的影响 | Chen, S.-C. | N/A | The impact of sugar diet on humidity preference, survival, and host landing in mosquitoes | |
| 从头设计平行和反平行A3B3异源六聚体α螺旋桶 | Chubb, J. J. | N/A | De novo design of parallel and antiparallel A3B3 heterohexameric alpha-helical barrels | |
| 生物系统中反馈调节的鲁棒性基本权衡 | Tran, N. H. N. | N/A | Fundamental trade-offs in the robustness of biological systems with feedback regulation | |
| 分裂RNA开关：通过预翻译和翻译后调控的集合实现基因表达的可编程和精确控制 | Abe, I. | N/A | Split RNA switch: Programmable and precise control of gene expression by ensemble of pre- and post-translational regulation | |
| 通过亚洲乳腺癌转录组测序检测肿瘤内微生物群 | Yeo, L.-F. | N/A | Detection of intra-tumoral microbiota from transcriptomic sequencing of Asian breast cancer | |
| 肠道微生物群移植后定植失败加剧了DSS诱导的结肠炎 | Gustafson, K. L. | N/A | Failure of colonization following gut microbiota transfer exacerbates DSS-induced colitis | |
| 甲型流感病毒通过细胞凋亡的启动诱导形成类似隧道纳米管的结构。 | Weir, D. | N/A | Influenza A viruses induce tunnelling nanotube-like structures through the onset of apoptosis | |
| 人α-防御素中和AAV2的机制 | Porter, J. M. | N/A | Mechanisms of AAV2 neutralization by human alpha-defensins | |
| 非光学、无标记的微生物电容成像技术 | Incandela, J. T. | N/A | Non-Optical, Label-free Electrical Capacitance Imaging of Microorganisms | |
| 掌握纯细菌菌株对微污染物完全分解的限制：一项蛋白质组学和动力学研究 | Gordillo, A. P. L. | N/A | Grasping the constraints of pure bacterial strains for the complete catabolism of micropollutants: a proteomic and kinetic study | |
| 铜绿假单胞菌LasR缺陷型突变体由于细胞内谷胱甘肽水平较低，表现出对甲基乙二醛和过氧化氢的敏感性增加。 | Ruzic, M. | N/A | Pseudomonas aeruginosa LasR-deficient mutants have increased methylglyoxal and hydrogen peroxide sensitivity due to low intracellular glutathione | |
| 河流至湖泊连续体中的异养固氮作用：生活方式及其对氮气固定的贡献 | Geisler, E. | N/A | Heterotrophic diazotrophy along a river to lake continuum: lifestyle and contribution to N2 fixation | |
| 耐碳青霉烯类肠杆菌霍氏菌利用黏液代谢促进胃肠道定殖 | Sinha, R. | N/A | Carbapenem-Resistant Enterobacter hormaechei Uses Mucus Metabolism to Facilitate Gastrointestinal Colonization | |
| 利用动态核极化增强的固态核磁共振技术对天然细菌生物膜进行高灵敏度分析 | Byeon, C.-H. | N/A | High-Sensitivity Analysis of Native Bacterial Biofilms Using Dynamic Nuclear Polarization-Enhanced Solid-State NMR | |
| 在公共蛋白质数据库中的未表征序列中，发现了数百种外源性和内源性RNA病毒RdRp序列。 | Brown, K. | N/A | Uncovering hundreds of exogenous and endogenous RNA viral RdRp sequences amongst uncharacterised sequences in public protein databases | |
| 白色念珠菌和金黄色葡萄球菌相互促进致病因素的分泌。 | Pasman, R. | N/A | Candida albicans and Staphylococcus aureus reciprocally promote secretion of virulence factors | |
| 鉴定出一种属于“flexivirus”相关家族的新型真菌病毒，其病毒粒子呈二十面体结构 | Wu, C.-F. | N/A | Identification of a novel mycovirus belonging to the ''flexivirus''-related family with icosahedral virion | |
| 鼻腔微生物群在人类鼻腔上皮类器官中差异定植并诱导细胞因子产生 | Boyd, A. I. | N/A | Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids | |
| 在虾生长的早期阶段施用钼酸盐可抑制虾池底部模型中硫化物的形成 | Torun, F. | N/A | Molybdate application in the early stages of shrimp growth suppresses sulphide formation in a shrimp pond bottom model | |
| 一种用于评估正布尼亚病毒神经疾病遗传决定因素的混合搭配反向遗传系统 | Miettinen, H. M. | N/A | A mix-and-match reverse genetics system for evaluating genetic determinants of orthobunyavirus neurological disease | |
| 重新审视氧毒性：超氧化物在缺乏SOD的细菌病原体中的进化与适应 | Huete, S. G. | N/A | Revisiting oxygen toxicity: evolution and adaptation to superoxide in a SOD-deficient bacterial pathogen | |
| 内生真菌枝孢菌BRN05的α-葡萄糖苷酶抑制活性和基于UHPLC-ESI-QTOF-MS的代谢谱分析，该菌株分离自大叶桃花心木的种子。 | Kumar, P. | N/A | Elucidation of α-glucosidase inhibitory activity and UHPLC-ESI-QTOF-MS based metabolic profiling of endophytic fungi Alternaria sp. BRN05. isolated from seeds of Swietenia macrophylla King. | |
| DNA甲基化和去甲基化驱动的脓毒症调控 | Saini, A. K. | N/A | DNA methylation and demethylation driven regulation of sepsis | |
| 一个赋能基因通路发现和基因表达辅助疾病分类的图谱引导框架 | Wang, Y. | N/A | A Graph Informed Framework Empowering Gene Pathway Discovery and Gene Expression-Assisted Disease Classification | |
| 通过使用具有一致N-连接糖基化抗原的HDX-MS实现糖蛋白的表位分析 | Ota, T. | N/A | Enabling Epitope Analysis of Glycoproteins via HDX-MS Using Antigens with Uni-formed N-linked Glycans | |
| 肌肉协同作用在神经肌肉骨骼建模中减少肌电图通道数量的初步研究 | Romanato, M. | N/A | Muscle synergies to reduce the number of electromyography channels in neuromusculoskeletal modelling: a pilot study | |
| varCADD：大量现有的遗传变异数据能够实现全基因组致病性预测 | Nazaretyan, L. | N/A | varCADD: large sets of standing genetic variation enable genome-wide pathogenicity prediction | |
| III型CRISPR-Cas位点中的环状核酸酶的多样性和丰度 | Hoikkala, V. | N/A | Diversity and abundance of ring nucleases in type III CRISPR-Cas loci | |
| 乳腺癌球体偏好活化的巨噬细胞作为共犯：一项体外研究 | Teli, A. | N/A | Breast cancer spheroids prefer activated macrophages as an accomplice: An in vitro study | |
| 多发性硬化症皮质中β淀粉样蛋白减少和神经原纤维缠结减少的神经病理学证据 | Pansieri, J. | N/A | Neuropathological evidence of reduced amyloid beta and neurofibrillary tangles in multiple sclerosis cortex | |
| 利用工程环境细菌降解PET塑料 | Banks, A. M. | N/A | Degradation of PET plastic with engineered environmental bacteria | |
| 真核生物可编程基因表达的正交转录引擎的定向进化 | Kar, S. | N/A | Directed evolution of an orthogonal transcription engine for programmable gene expression in eukaryotes | |
| 信号序列将酶和结构蛋白靶向细菌微区室，对微区室的形成至关重要。 | Johnson, E. R. | N/A | Signal sequences target enzymes and structural proteins to bacterial microcompartments and are critical for microcompartment formation | |
| 鸟类干扰素调节因子（IRF）家族团聚：IRF3与IRF9相聚 | Ungrova, L. | N/A | Avian interferon regulatory factor (IRF) family reunion: IRF3 and IRF9 found | |
| SbcB 以不依赖核酸外切酶的方式促进霍乱弧菌的自然转化 | Dalia, T. N. | N/A | SbcB facilitates natural transformation in Vibrio cholerae in an exonuclease-independent manner | |
| 完整细菌鞭毛的细胞外结构揭示了鞭毛蛋白插入的机制 | Einenkel, R. | N/A | Structure of the complete extracellular bacterial flagellum reveals mechanism for flagellin incorporation | |
| 培养的肺泡基底细胞显示出与气道基底细胞相似的特征和功能特性。 | Blumer, S. | N/A | Cultured alveolar basal cells display similar characteristics and functional properties to airway basal cells | |
| 人类GPR155的冷冻电镜结构揭示了其调控和转运机制 | Sharma, M. | N/A | Cryo-EM structures of human GPR155 elucidate its regulatory and transport mechanisms | |
| # BioRxiv 2024-09-24 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 内吞循环在昼夜节律性胶原蛋白纤维形成中起核心作用，并在纤维化过程中受到破坏。 | CHANG, J. | N/A | Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis | |
| Rab10失活促进AMPAR插入和树突棘增大在长时程增强过程中 | Wang, J. | N/A | Rab10 inactivation promotes AMPAR insertion and spine enlargement during long-term potentiation | |
| 基于CRISPR-Cas的微同源介导的末端连接用于植物中精确基因替换 | Vu, T. V. | N/A | CRISPR-Cas-based Microhomology-Mediated End Joining for Precise Gene Replacement in Plant | |
| 已撤回：拟南芥三羧酸循环中涉及的调控蛋白质的计算机分析及通过Alphafold和其他软件进行的结构分析 | Nayab, H. | N/A | WITHDRAWN: In-silico analysis of regulatory proteins involved in tricarboxylic acid cycle of Arabidopsis thaliana and structural analysis by Alphafold and other software | |
| 热循环-高温下调了脂多糖诱导的人血炎症，并有助于清除单纯疱疹病毒1型 | Kuo, Y.-Y. | N/A | Thermal cycling-hyperthermia down-regulates liposaccharide-induced inflammation in human blood and helps with clearance of herpes simplex virus type 1 | |
| 脑细胞外基质中的硫酸化糖胺聚糖取代了细胞外氯离子 | Normoyle, K. P. | N/A | Displacement of extracellular chloride by sulfated glycosaminoglycans of the brain extracellular matrix | |
| 中度元基因组学：一种从环境样本中无需培养即可重建微生物基因组的新方法 | Vollmers, J. | N/A | Midi-metagenomics: A novel approach for cultivation independent microbial genome reconstruction from environmental samples | |
| Hsf1-sHsp级联在蚊子细胞中具有广谱抗病毒活性 | Qu, J. | N/A | The Hsf1-sHsp cascade has pan-antiviral activity in mosquito cells | |
| 鞭毛开关反向重复序列影响鞭毛的可逆性，并因梭状芽孢杆菌RT027/MLST1的毒力而异。 | Nhu, N. T. Q. | N/A | Flagellar switch inverted repeat impacts flagellar invertibility and varies Clostridioides difficile RT027/MLST1 virulence. | |
| 对费氏弧菌中环二鸟苷酸调节蛋白的功能分析 | Isenberg, R. Y. | N/A | Functional analysis of cyclic diguanylate-modulating proteins in Vibrio fischeri | |
| 突变顺序和上位性决定了FBXW7突变在结直肠癌进化中的后果 | Chan, D. K. H. | N/A | Mutational order and epistasis determine the consequences of FBXW7 mutations during colorectal cancer evolution | |
| 双路径架构使慢性压力能够破坏自主性并促进习惯的形成。 | Giovanniello, J. R. | N/A | A dual-pathway architecture enables chronic stress to disrupt agency and promote habit formation | |
| 硅藻CO2固定器官的蛋白质蓝图 | Nam, O. | N/A | A Protein Blueprint of the Diatom CO2-Fixing Organelle | |
| 在剪接泛基因组图上对选择性剪接事件进行差异定量 | Ciccolella, S. | N/A | Differential quantification of alternative splicing events on spliced pangenome graphs | |
| 心脏交感和副交感指数的稳健且时间分辨的估计 | Candia-Rivera, D. | N/A | Robust and time-resolved estimation of cardiac sympathetic and parasympathetic indices | |
| 水平转移的无细胞染色质颗粒在宿主细胞内作为自主捕食性基因组和转座元件的载体发挥作用。 | Banerjee, S. | N/A | Horizontally transferred cell-free chromatin particles function as autonomous predatory genomes and vehicles for transposable elements within host cells | |
| RomX是一种新型原核调节因子，它将RomR的响应接收域与GTP结合的MglA连接起来，以建立Myxococcus xanthus的极性。 | Chakraborty, S. | N/A | RomX, a novel prokaryotic regulator, links the response receiver domain of RomR with GTP-bound MglA for establishing Myxococcus xanthus polarity | |
| 大声朗读与默读过程中信息权重的差异：基于fMRI数据表征相似性分析的证据 | Bailey, L. M. | N/A | Differential weighting of information during aloud and silent reading: Evidence from representational similarity analysis of fMRI data | |
| CPT1A在结直肠癌中调节辐射敏感性 | Chen, Z. | N/A | CPT1A Mediates Radiation Sensitivity in Colorectal Cancer | |
| 盐诱导的根冠比自然变异揭示SR3G为拟南芥根栓化及盐韧性的负调控因子 | Ishka, M. R. | N/A | Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis | |
| 学习从快速手动点注释中精确分割神经纤维缠结 | Ghandian, S. | N/A | Learning precise segmentation of neurofibrillary tangles from rapid manual point annotations | |
| 在生长表面上超无序的细胞排列 | Ross, R. J. H. | N/A | Hyperdisordered cell packing on a growing surface | |
| 利用基因组数据预测的气候适宜性比较加利福尼亚海峡群岛橡树（Quercus tomentella）的保护策略 | Mead, A. | N/A | Comparison of conservation strategies for California Channel Island Oak (Quercus tomentella) using climate suitability predicted from genomic data | |
| 定义肺癌细胞对表观遗传抑制反应的异质分子图谱 | Lin, C. | N/A | Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition | |
| 在铜绿假单胞菌临床分离株中，前噬菌体与抗生素耐药性的关联并不常见。 | Chang, T. H. | N/A | Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates | |
| 在铜绿假单胞菌临床分离株中，前噬菌体与抗生素耐药性的关联并不常见。 | Chang, T. H. | N/A | Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates | |
| 清洁死者：优化的去污方法提升更新世骨骼材料的古蛋白质组学分析效果 | Fagernäs, Z. | N/A | Cleaning the Dead: Optimized decontamination enhances palaeoproteomic analyses of Pleistocene skeletal material | |
| 空间转录组学鉴定出新型铜绿假单胞菌毒力因子 | Zhou, H. | N/A | Spatial transcriptomics identifies novel Pseudomonas aeruginosa virulence factors | |
| 遗传逻辑电路的能量感知技术映射 | Kubaczka, E. | N/A | Energy Aware Technology Mapping of Genetic Logic Circuits | |
| 小鼠GnRH神经元在体内的多维振荡活动 | Han, S. Y. | N/A | Multi-dimensional oscillatory activity of mouse GnRH neurons in vivo | |
| 斑马鱼HoxA和HoxD相关簇在胸鳍发育中的功能作用 | Ishizaka, M. | N/A | The functional roles of zebrafish HoxA- and HoxD-related clusters in the pectoral fin development | |
| 质粒病毒维持能够使细菌种群从感染中恢复，并实现病毒与细菌的共存。 | Sanchez-Martinez, R. | N/A | Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence | |
| 有毒的蓝光通过驱动肠道微生物介导的脂质积累，在果蝇中建立耐受性 | Takada, Y. | N/A | Toxic blue light drives the gut microbiota-mediated lipid accumulation to build tolerance in Drosophila | |
| 功能成像和连接组分析揭示了果蝇味觉回路的组织原理 | Li, J. | N/A | Functional imaging and connectome analyses reveal organizing principles of taste circuits in Drosophila | |
| 评估生理指标在通过比较问题测试（CQT）检测欺骗和诚实性中的应用 | Rashid, A. M. S. | N/A | Evaluating Physiological Indicators in Detecting Deception and Truthfulness using theComparison Question Test (CQT) | |
| 评估生理指标在通过比较问题测试（CQT）检测欺骗和真实性中的应用 | Rashid, A. M. S. | N/A | Evaluating Physiological Indicators in Detecting Deception and Truthfulness using the Comparison Question Test (CQT) | |
| 一种生理学启发的混合CPG/反射控制器，用于自行车模拟，并可推广至步行 | Severini, G. | N/A | A physiologically inspired hybrid CPG/Reflex controller for cycling simulations that generalizes to walking | |
| 癌症-免疫共进化由抗原突变积累所决定 | Wang, L. | N/A | Cancer-immune coevolution dictated by antigenic mutation accumulation | |
| 豆科植物共生基因的突变在多菌株接种过程中为根瘤菌的自然遗传变异创造了一个复杂的选择性环境。 | Guha, S. | N/A | Mutations in legume symbiosis genes create a complex selective landscape for natural genetic variation in rhizobia during multi-strain inoculations | |
| AyurPhenoClusters 定义了罕见疾病的共同分子根源，并揭示了综合征条件下纤毛功能障碍。 | Joshi, A. | N/A | AyurPhenoClusters define common molecular roots for rare diseases and uncover ciliary dysfunctions in syndromic conditions | |
| 灵长类新皮层中是否存在普遍的局部场电位功率频谱层状模式？ | Mackey, C. A. | N/A | Is there a ubiquitous spectrolaminar motif of local field potential power across primate neocortex? | |
| 通过基于CRISPR/Cas9 RNP的植物体内基因编辑技术培育出的长保质期甜瓜 | Sasaki, K. | N/A | A long shelf-life melon created via CRISPR/Cas9 RNP-based in planta genome editing | |
| 液滴测序揭示口腔生物膜外泌体中的毒力基因簇 | Takano, S. | N/A | Droplet Sequencing Reveals Virulence Gene Clusters in Oral Biofilm Extracellular Vesicles | |
| GWA-X：一个可扩展的GPU加速包，用于全基因组关联研究中的排列检验 | Agung, M. | N/A | GWA-X: An Extensible GPU Accelerated Package for Permutation Testing in Genome-Wide Association Studies | |
| 泛基因组启发的语言模型用于隐私保护的合成基因组序列生成 | Huang, P. | N/A | Pangenome-Informed Language Models for Privacy-Preserving Synthetic Genome Sequence Generation | |
| 海马体γCaMKII的多巴胺化促进突触到核的信号传递及记忆形成 | Stewart, A. F. | N/A | Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation | |
| 外生菌根真菌松乳菇（Suillus luteus）在原生和引入种群中的生物合成基因簇多样性 | Allen, B. M. | N/A | Biosynthetic Gene Cluster Diversity Across Native and Introduced Populations of an Ectomycorrhizal Fungus, Suillus luteus | |
| GCK-MODY中独特的持续时间和饮食依赖性脂质谱及肾并发症 | Huang, Y. | N/A | Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY | |
| 造血干细胞来源的脂肪细胞消融减少了同基因小鼠高级别浆液性癌模型中的肿瘤负荷 | Woodruff, E. R. | N/A | Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma | |
| 利用光遗传学技术快速可逆地调控出芽酵母细胞周期的进展 | Koutsoumpa, A. | N/A | Rapid and reversible regulation of cell cycle progression in budding yeast using optogenetics | |
| 胆碱能神经元活性通过毒蕈碱信号传导促进弥漫性中线胶质瘤的生长 | Drexler, R. | N/A | Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling | |
| 膜相关传送带控制细菌第9型分泌系统的旋转方向 | Trivedi, A. | N/A | A membrane-associated conveyor belt controls the rotational direction of the bacterial type 9 secretion system | |
| 量化生物研究中条形图的数据失真 | Lin, T.-J. | N/A | Quantifying Data Distortion in Bar Graphs in Biological Research | |
| 人类肺部先天性和适应性免疫细胞的动态反应突显了哮喘风险位点基因的作用 | Tian, F. | N/A | Dynamic responses of human lung innate and adaptive immune cells highlight the roles of genes at asthma risk loci | |
| 在受控的人类流感病毒感染后，先天免疫的表观基因组景观 | Thistlethwaite, W. | N/A | Innate immune epigenomic landscape following controlled human influenza virus infection | |
| 加尔瓦宁是一种用于定向细胞迁移的电场传感器。 | Belliveau, N. M. | N/A | Galvanin is an electric-field sensor for directed cell migration | |
| 果蝇发育翅膀中立方上皮向扁平上皮转变的机械调控 | Harmansa, S. | N/A | Mechanical regulation of cuboidal-to-squamous epithelial transition in the Drosophila developing wing | |
| Elavl1对于附肢骨骼发育并非必需。 | Parsha, R. | N/A | Elavl1 is dispensable for appendicular skeletal development | |
| PAEP、KRT10和BMP7基因SNPs与克莱猪繁殖性状的关联分析 | Zhao, Y. | N/A | Association analysis of PAEP, KRT10 and BMP7 Genes SNPs with reproductive traits in Kele pigs | |
| 保护基因组研究中的隐私：作者全面框架 | Ghasemian, M. | N/A | Safeguarding Privacy in Genome Research: A Comprehensive Framework for Authors | |
| 基于网络药理学、分子对接及细胞实验探讨滋癸益冲方减轻卵巢早衰中卵泡颗粒细胞凋亡的机制 | Zhang, X. | N/A | Explore the mechanism of Zigui Yichong Formula in reducing the apoptosis of ovarian granulosa cells in premature ovarian insufficiency based on network pharmacology, molecular docking and cell experiments | |
| 构建儿童科学绘画的规范：基于大语言模型语义相似性的分布特征 | Zhang, Y. | N/A | Constructing a Norm for Children's Scientific Drawing: Distribution Features Based on Semantic Similarity of Large Language Models | |
| 探究视觉素养技能揭示了学生对染色体尺度与抽象概念的理解。 | Uminski, C. | N/A | Probing visual literacy skills reveals student conceptions of scale and abstraction with respect to chromosomes | |
| 丙酮酸的命运通过调节细胞的氧化还原电位来决定细胞的生长。 | Toshniwal, A. G. | N/A | The fate of pyruvate dictates cell growth by modulating cellular redox potential | |
| 表面递送定量揭示了成簇的protocadherin异构体之间不同的运输效率 | May, E. J. | N/A | Surface delivery quantification reveals distinct trafficking efficiencies among clustered protocadherin isoforms | |
| 振动幅度在红眼树蛙胚胎逃逸孵化反应中的作用 | Jung, J. | N/A | The role of vibration amplitude in the escape hatching response of red-eyed treefrog embryos | |
| erm-1的本地化翻译有助于ERM-1在秀丽隐杆线虫胚胎中的功能 | Salm, E. v. d. | N/A | Localized translation of erm-1 contributes to ERM-1 function in the C. elegans embryo | |
| 高WEE1表达与多发性骨髓瘤患者的不良生存率独立相关。 | Simhal, A. K. | N/A | High WEE1 expression is independently linked to poor survival in multiple myeloma | |
| 早期阿尔茨海默病中突触密度与代谢型谷氨酸受体之间关系的评估：一项多示踪剂PET研究 | Salardini, E. | N/A | Assessment of the relationship between synaptic density and metabotropic glutamate receptors in early Alzheimer's disease: a multi-tracer PET study | |
| 发酵底物的分解代谢性质影响无氧生长下大肠杆菌的蛋白质组重构 | Momin, H. | N/A | The catabolic nature of fermentative substrates influence proteomic rewiring in Escherichia coli under anoxic growth | |
| 通过表征VGLUT1mEos2敲低的新型小鼠模型，揭示了VGLUT1表达水平对量子大小的一个微小影响。 | Zhang, X. M. | N/A | A minor impact of VGLUT1 expression level on quantal size revealed through the characterization of VGLUT1mEos2 knock-down new mouse model | |
| 脊髓损伤引起的脑部炎症和认知能力下降可以通过脊髓细胞移植得到逆转。 | Delarue, Q. | N/A | Brain inflammation and cognitive decline induced by spinal cord injury can be reversed by spinal cord cell transplants | |
| 小鼠上丘视觉表征的扫视调制神经基质 | Hunt, J. | N/A | Neural substrates for saccadic modulation of visual representations in mouse superior colliculus | |
| 绿色合成氧化铁/石墨烯磁性纳米复合材料作为新型抗菌材料的制备 | Kazazi, M. | N/A | Production of green synthesized iron oxide/graphene magnetic nanocomposite as a novel antibacterial material | |
| 环境泥炭藓相关真菌通过靶向硫醇稳态与结核分枝杆菌竞争。 | Malhotra, N. | N/A | Environmental sphagnum-associated fungi target thiol homeostasis to compete with Mycobacterium tuberculosis. | |
| 利用背腹侧亨廷顿病类器官和亨廷顿病小鼠胚胎鉴定幼年亨廷顿病细胞群体的神经发育组织 | Switonska-Kurkowska, K. | N/A | Identification of neurodevelopmental organization of the cell populations of juvenile Huntington's disease using dorso-ventral HD organoids and HD mouse embryos | |
| 埃及伊蚊中肠提取物的全面蛋白水解分析：揭示血液餐蛋白消化系统 | O'Donoghue, A. J. | N/A | Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system | |
| 胎儿特异性基因LIN28B对人类胎儿B淋巴细胞生成至关重要，并参与KMT2A::AFF1婴儿白血病的启动。 | Ling, R. E. | N/A | The fetal specific gene LIN28B is essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia | |
| H9c2分化的优化导致无需添加视黄酸即可形成钙活性及横纹肌心脏细胞。 | Brock, J. | N/A | Optimization of H9c2 differentiation leads to calcium-active and striated cardiac cells without addition of retinoic acid. | |
| habtools：一个用于计算表面和物体三维指标的R包 | Schiettekatte, N. M. | N/A | habtools: an R package to calculate 3D metrics for surfaces and objects | |
| 一种用于检测陆地动物环境DNA的地面表面滚动方法 | Kakita, M. | N/A | A ground surface rolling method for detecting environmental DNA of terrestrial animals | |
| 在考虑父亲精子储存的情况下，没有证据表明父亲的年龄对儿子或女儿有影响。 | Sanghvi, K. | N/A | No evidence for paternal age effects on sons or daughters, when accounting for paternal sperm storage | |
| 野外采集的伊蚊中自然存在的沃尔巴克氏菌的全球流行率：一项系统综述和荟萃分析 | Gebremariam, T. T. | N/A | Global prevalence of naturally occurring Wolbachia in field-collected Aedes mosquitoes: a systematic review and meta-analysis | |
| 与心血管疾病相关的非编码变异破坏了GATA4-DNA结合及其调控功能 | Pena-Martinez, E. G. | N/A | Cardiovascular Disease-Associated Non-Coding Variants Disrupt GATA4-DNA Binding and Regulatory Functions | |
| 原位通用正交网络（UNION）生物墨水沉积技术用于直接输送角膜基质干细胞至角膜伤口 | Brunel, L. G. | N/A | In Situ UNIversal Orthogonal Network (UNION) Bioink Deposition for Direct Delivery of Corneal Stromal Stem Cells to Corneal Wounds | |
| 将3D打印机用作绘图仪，为进行二维迁移分析开辟了一个全新的领域。 | Köppe, H. | N/A | The use of 3D-printers as plotters opens up a new world in performing 2D migration analyses | |
| 假马齿苋植物化学物质作为阿尔茨海默病治疗中有前景的BACE1抑制剂 | Sangeet, S. | N/A | Bacopa monnieri phytochemicals as promising BACE1 inhibitors for Alzheimers Disease Therapy | |
| 对于脊椎动物胚胎发育而言，基因表达谱的PCA（主成分分析）解释性不如慷慨性。 | Ogata, N. | N/A | Liberality is More Explainable than PCA of Transcriptome for Vertebrate Embryo Development | |
| IκBζ的组成性表达促进黑色素瘤的生长并导致免疫疗法抵抗 | Kolb, A. | N/A | Constitutive expression of IκBζ promotes tumor growth and immunotherapy resistance in melanoma | |
| 使用DARPin选择性靶向TBXT可识别脊索瘤中的调控网络和治疗脆弱性 | Umbaugh, C. S. | N/A | Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma | |
| miR-21：一种在高脂饮食小鼠中延缓重度肝病和肝细胞癌的治疗靶点 | Jagtap, U. | N/A | miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice | |
| Rho/MRTF抑制诱导的黑色素瘤细胞凋亡事件及其对药物耐药性的预防机制探讨：涉及pirin的潜在作用 | Foda, B. | N/A | Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: Implications for the involvement of pirin | |
| C57BL/6J小鼠在家庭笼中的乙醇饮用和操作性自我给药中的性别差异，但由谷氨酸AMPAR活性进行的调节是等效的。 | Faccidomo, S. | N/A | Sex Differences in Home-Cage Ethanol Drinking and Operant Self-Administration in C57BL/6J Mice but Equivalent Regulation by Glutamate AMPAR Activity | |
| 在阿尔茨海默病3xTg小鼠模型中，许多热量限制的好处需要禁食才能实现。 | Babygirija, R. | N/A | Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer&aposs disease | |
| 不同浓度吲哚乙酸（IAA）对不同李（Prunus domestica L.）栽培品种形态特征的响应 | Ullah, K. | N/A | Response of Various Concentrations of Indole Acetic Acid (IAA) to Morphological Attributes in Different Plum (Prunus domestica L.) Curltivars | |
| 肝脏中一种矛盾的肿瘤抗原特异性反应 | Trehan, R. S. | N/A | A Paradoxical Tumor Antigen Specific Response in the Liver | |
| 用于评估恒河猴支气管肺泡灌洗液中白细胞的细胞和功能表型的42参数质谱流式细胞术面板 | Makatsa, M. S. | N/A | 42-parameter mass cytometry panel to assess cellular and functional phenotypes of leukocytes in bronchoalveolar lavage of Rhesus macaque | |
| 可变大小群体中一般家谱的TMRCA | Wemces, A. H. | N/A | The TMRCA of general genealogies in populations of variable size | |
| 下一代雪豹种群评估工具：用于从粪便中个体识别的多重PCR SNP面板 | Solari, K. A. | N/A | Next-generation snow leopard population assessment tool: multiplex-PCR SNP panel for individual identification from feces | |
| 桥本甲状腺炎背景下甲状腺乳头状癌的蛋白质组学分析 | Zhou, H. | N/A | Proteomic analysis of papillary thyroid carcinoma in the context of Hashimoto's thyroiditis | |
| 学习增强型草图绘制技术在保护隐私和安全的基因组关联分析（GWAS）中提供了改进的性能。 | Xu, J. | N/A | Learning-Augmented Sketching Offers Improved Performance for Privacy Preserving and Secure GWAS | |
| 结构解析：脯氨酸富集区域在Tau功能中的作用 | Acosta, K. | N/A | Structural Insights into the Role of the Proline Rich Region in Tau Function | |
| 基于机器学习的癌症及转移中整合素表达模式研究 | Shadman, H. | N/A | A Machine Learning-Based Investigation of Integrin Expression Patterns in Cancer and Metastasis | |
| 在衰老的狒狒中，前额叶皮层线粒体生物能量学的性别特异性下降与行走速度相关 | Adekunbi, D. A. | N/A | Sex-specific decline in prefrontal cortex mitochondrial bioenergetics in aging baboons correlates with walking speed | |
| 成纤维细胞的空间编程通过排除免疫细胞促进组织炎症的消退 | Reis Nisa, P. | N/A | Spatial programming of fibroblasts promotes resolution of tissue inflammation through immune cell exclusion | |
| MDA5 ISGylation 对免疫信号传导至关重要，可调控病毒复制和发病机制 | Sarkar, L. | N/A | MDA5 ISGylation is crucial for immune signaling to control viral replication and pathogenesis | |
| 胞外cGAMP及其类似物对T细胞的毒性是由于SLC7A1介导的导入所致。 | Sudaryo, V. | N/A | Toxicity of extracellular cGAMP and its analogs to T cells is due to SLC7A1-mediated import | |
| 独立的鸟类表观遗传时钟用于衰老和发育 | Haller, A. | N/A | Independent avian epigenetic clocks for aging and development | |
| 切尔诺贝利啮齿动物中代谢率与放射性剂量率的协变关系 | Boratynski, Z. | N/A | Covariation between metabolic and radioactive dose rates in Chornobyl rodents | |
| 森林转化为农业用地降低了我国西南岩溶石漠化地区土壤黑碳组分含量。 | Zhang, D. | N/A | The conversion of forests to agricultural land reduced the content of soil black carbon fractions in a karst rocky desertification area of Southwest China | |
| 拟除虫菊酯类杀虫剂是否会影响敏捷蛙（Rana dalmatina）的性别比例？ | Balogh, E. | N/A | Do pyrethroid insecticides influence sex ratios in agile frogs (Rana dalmatina)? | |
| 热带森林中相邻生境的真菌群落时空动态和组装过程存在差异 | Lin, C.-P. | N/A | Spatiotemporal dynamics and assembly process differ in fungal communities across contiguous habitats in tropical forests | |
| 蚜虫宿主转换的触发因素及决定机制解析 | Etier, A. | N/A | Insights into the triggering factors and determination mechanisms of host alternation in aphids | |
| 有限种群结构但存在近期选择信号：引入北美洲的非洲无花果蝇（Zaprionus indianus） | Erickson, P. A. | N/A | Limited population structure but signals of recent selection in introduced African Fig Fly (Zaprionus indianus) in North America | |
| 南美慈鲷鳍骨的可塑性受觅食方式改变的影响 | Gilbert, M. | N/A | Plasticity in the pectoral fin skeleton is induced by altered foraging regime in a South American cichlid | |
| 建立一个全球地下动物条形码参考库 | Guzik, M. T. | N/A | Towards a global barcode reference library for subterranean fauna | |
| 同义突变和单核苷酸变化有助于水平转移基因的适应性。 | Venkataraman, P. | N/A | Synonymous and single nucleotide changes facilitate the adaptation of a horizontally transferred gene. | |
| 古老的倒位多态性在一种广泛分布的蝴蝶物种中具有局部适应性。 | Seixas, F. A. | N/A | Ancient inversion polymorphisms are locally adaptive in a widespread butterfly species | |
| 性状依赖的生物地理学为梅桂（番荔枝科）在澳大拉西亚-太平洋地区的扩散提供了见解 | Liu, M.-F. | N/A | Trait-dependent biogeography offers insights on the dispersal of Meiogyne (Annonaceae) across the Australasia-Pacific region | |
| 在按蚊细胞中进行的全基因组CRISPR筛选鉴定了必需基因和氯膦酸盐脂质体功能所需的成分 | Mameli, E. | N/A | A genome-wide CRISPR screen in Anopheles mosquito cells identifies essential genes and required components of clodronate liposome function | |
| 种系丢失减少了体细胞线粒体，但在衰老和低温过程中保留了呼吸功能。 | Hwang, H. | N/A | Germline loss diminishes somatic mitochondria but confers preservation of respiratory function during aging and hypothermia | |
| 生物银行规模和分布式数据集中SNP遗传力的分析和计算解决方案 | Qi, G.-A. | N/A | Analytical and computational solution for the estimation of SNP-heritability in biobank-scale and distributed datasets | |
| 精心挑选的转录组数据集，用于研究病毒呼吸道接种和疫苗接种后血液和鼻样本的转录反应 | Lan, Z. | N/A | A curated collection of transcriptome datasets to study the transcriptional response in blood and nasal samples following viral respiratory inoculation and vaccination | |
| 高拷贝数子宫内膜癌中超倍体基因型的功能影响 | Florio, A. | N/A | Functional impact of the hyperduplication genomophenotype in high copy number endometrial cancer | |
| 从头组装和注释飞虱线粒体基因组 | Molligan, J. | N/A | De novo assembly and annotation of the Empoasca fabae mitochondrial genome | |
| 从斑点到细胞：使用BOMS在空间转录组学中进行细胞分割 | Kamboj, O. | N/A | From spots to cells: Cell segmentation in spatial transcriptomics with BOMS | |
| 面对不断变化的海域，关键沿海生物扰动者Hediste diversicolor的分子武器库 | Beine, K. | N/A | The molecular arsenal of the key coastal bioturbator Hediste diversicolor faced with changing oceans | |
| 机器学习优化的选择性剪接靶向检测 | Yang, K. | N/A | Machine learning-optimized targeted detection of alternative splicing | |
| 转座元件在自然界中普遍作为跨代表观遗传继承的载体 | Baduel, P. | N/A | Transposable elements are prevalent vectors of transgenerational epigenetic inheritance in nature | |
| 在严格一夫多妻制的木蚁物种中，超级基因的丧失 | Sigeman, H. | N/A | The loss of a supergene in obligately polygynous Formica wood ant species | |
| 已建立的硫肽串联质谱行为和硫酸转移酶测定法否定了酪氨酸硫酸化作为组蛋白标记的可能性 | Youssef, M. M. | N/A | Established Sulfopeptide Tandem Mass Spectrometry Behavior and Sulfotransferase Assays Refute Tyrosine Sulfation as a Histone Mark | |
| 直接且超灵敏的生物发光检测完整呼吸道病毒 | Grawe, A. | N/A | Direct and ultrasensitive bioluminescent detection of intact respiratory viruses | |
| AlphaFold3在抗体和纳米抗体对接方面学到了什么，还有哪些问题尚未解决？ | Hitawala, F. N. | N/A | What has AlphaFold3 learned about antibody and nanobody docking, and what remains unsolved? | |
| snCED-seq：用于FFPE组织单核RNA测序的高保真冷冻酶解离核技术 | yunxia, G. | N/A | snCED-seq: High-fidelity cryogenic enzymatic dissociation of nuclei for single-nucleus RNA-seq of FFPE tissues | |
| 通过海洋甲烷氧化菌-微藻共培养生产依克多因，实现了生物气的完全价值化。 | Ruiz-Ruiz, P. | N/A | Ectoine production through a marine methanotroph-microalgae culture allows complete biogas valorization | |
| 细菌谱系中脯氨酰寡肽酶及相关序列的鉴定与研究 | Nayak, S. D. | N/A | Identification and study of Prolyl Oligopeptidases and related sequences in bacterial lineages | |
| 通过结合与对称性相关的分子来提高姿态预测的准确性 | Vijayan, D. | N/A | Improving the accuracy of pose prediction by incorporating symmetry-related molecules | |
| 子宫内膜异位症中焦亡相关基因的鉴定与诊断潜力：一项新颖的生物信息学分析 | Teng, P. | N/A | Identification and Diagnostic Potential of Pyroptosis-Related Genes in Endometriosis: A Novel Bioinformatics Analysis | |
| 通过综合计算机方法鉴定隐孢子虫肌苷5'-单磷酸脱氢酶的潜在抑制剂 | Al-Mamun, A. | N/A | Identification of potential inhibitors against Inosine 5'-Monophosphate Dehydrogenase of Cryptosporidium parvum through an integrated in silico approach | |
| 在单细胞RNA测序中，利用scPCA联合建模细胞异质性和条件效应 | Vohringer, H. S. | N/A | Joint Modeling of Cellular Heterogeneity and Condition Effects with scPCA in Single-Cell RNA-Seq | |
| 设计具有所需熔化温度的热稳定蛋白质 | Tijare, P. | N/A | Designing of thermostable proteins with a desired melting temperature | |
| 探索中肠表达动力学：成年雌性美洲钝眼蜱中肠的纵向转录组分析及与其他硬蜱物种的比较见解 | Lu, S. | N/A | Exploring midgut expression dynamics: longitudinal transcriptomic analysis of adult female Amblyomma americanum midgut and comparative insights with other hard tick species | |
| 解码蛋白质动力学：ProFlex作为正常模式分析中的语言桥梁 | Magill, D. | N/A | Decoding Protein Dynamics: ProFlex as a Linguistic Bridge in Normal Mode Analysis | |
| 代谢建模揭示了拟南芥热生长反应的决定因素 | Wendering, P. | N/A | Metabolic modeling identifies determinants of thermal growth responses in Arabidopsis thaliana | |
| MolAR：用Rust编写的MD模拟分析内存安全库 | Yesylevskyy, S. | N/A | MolAR: memory-safe library for analysis of MD simulations written in Rust | |
| 基于Martini的酶粗粒化模型的框架：模型开发与实验验证 | Hooten, M. | N/A | Framework for Martini-based Coarse-grained Model of Enzymes: Model Development and Experimental Validation | |
| 老化大鼠模型中与认知相关的蛋白质结构变化与减少的重折叠能力有关 | Tarbox, H. E. | N/A | Cognition-Associated Protein Structural Changes in a Rat Model of Aging are Related to Reduced Refolding Capacity | |
| 纤维蛋白凝块的介观模拟：凝胶点处流变学与微观结构的相互作用 | Zohravi, E. | N/A | Mesoscale Modelling of Fibrin Clots: The Interplay between Rheology and Microstructure at the Gel Point | |
| 流动状态下二元混合物中的主动分离 | Di Dio, G. | N/A | Active segregation in binary mixtures under flow | |
| 一种开放量子系统方法用于Bicoid梯度动力学 | Lone, I. | N/A | An Open Quantum System Approach to Bicoid Gradient Dynamics | |
| ATP合酶亚基e（ATP5I）在介导双胍类药物的代谢和抗增殖效应中的作用 | Lefrancois, G. | N/A | The Role of ATP Synthase Subunit e (ATP5I) in Mediating the Metabolic and Antiproliferative Effects of Biguanides | |
| 食管腺癌与正常邻近组织间蛋白质表达的比较分析 | Nicholas, B. | N/A | Comparative analysis of protein expression between oesophageal adenocarcinoma and normal adjacent tissue | |
| 北美野生河狸（Castor canadensis）的尸检结果揭示了对加利福尼亚淡水生态系统的潜在威胁 | Gonzales-Viera, O. A. | N/A | Postmortem findings of free-ranging North American beavers (Castor canadensis) reveal potential threats to California freshwater ecosystems | |
| 通过疾病相关微生物群重新审视葡萄藤酸腐病：三重共感染？ | Hevin, S. | N/A | Revisiting sour rot of grapevine through disease-associated microbiomes: a tripartite co-infection? | |
| 通过行为分析进行毒性测试，观察有机溶剂对秀丽隐杆线虫的普遍和特定不良影响 | Tomioka, M. | N/A | Observation of general and specific adverse effects of organic solvents on Caenorhabditis elegans by toxicity testing using behavioral analysis | |
| 刺激调制稳态法：事件相关功能磁共振成像的新范式。 | Mathew, R. | N/A | Stimulus-modulated approach to steady-state: A new paradigm for event-related fMRI. | |
| 肿瘤诱导的内皮细胞RhoA激活介导肿瘤细胞跨内皮迁移和转移 | Sajib, M. S. | N/A | Tumor-induced endothelial RhoA activation mediates tumor cell transendothelial migration and metastasis | |
| 在Cyp17a1敲除大鼠中，从内脏脂肪向皮下脂肪的转变阻止了代谢综合征的进展 | Jeon, B.-J. | N/A | Shift from visceral to subcutaneous fat in Cyp17a1 knockout rats prevent the progression of metabolic syndrome | |
| ALMS1 KO大鼠：一种具有自发性高血压的新型代谢综合征模型 | Jaykumar, A. B. | N/A | ALMS1 KO rat: a new model of metabolic syndrome with spontaneous hypertension | |
| 小鼠在二氧化碳挑战下的血管反应 | Yang, X. | N/A | Vascular responses of hypercapnia challenge in mice | |
| 高光谱成像在遥感山毛榉树皮病初期方面能力有限。 | Tougas, G. | N/A | Hyperspectral imaging has a limited ability to remotely sense the onset of beech bark disease | |
| 高阶和分布式协同功能相互作用在目标导向学习中编码信息增益 | Combrisson, E. | N/A | Higher-order and distributed synergistic functional interactions encode information gain in goal-directed learning | |
| 人类和小鼠神经元皮层可分离性的内在特征识别 | Yun, Z. | N/A | Identification of Intrinsic Features for Cortical Separability of Human and Mouse Neurons | |
| 前额叶皮层中视觉运动神经元的贝叶斯推理 | Langlois, T. | N/A | Bayesian inference by visuomotor neurons in prefrontal cortex | |
| 永久性噪音引起的听力损失后的听觉决策缺陷 | Berns, M. P. | N/A | Auditory decision-making deficits after permanent noise-induced hearing loss | |
| 先天失明个体腹侧视觉流中对物体镜像的重复抑制，而非对盲文字母的重复抑制 | Korczyk, M. | N/A | Repetition suppression for mirror images of objects and not Braille letters in the ventral visual stream of congenitally blind individuals | |
| 多效营养因子缺失可预防高脂饮食引起的认知功能障碍、神经胶质反应及海马区周围神经网的变化。 | Caneque-Rufo, H. | N/A | Pleiotrophin deletion prevents high-fat diet-induced cognitive impairment, glial responses, and alterations of the perineuronal nets in the hippocampus | |
| 低强度脉冲超声波激活培养的海马神经元中的兴奋性突触网络 | Li, F. | N/A | Low intensity pulsed ultrasound activates excitatory synaptic networks in cultured hippocampal neurons | |
| 体感皮层与身体表征：在视觉-本体感觉线索冲突期间更新运动系统 | Mirdamadi, J. L. | N/A | Somatosensory cortex and body representation: Updating the motor system during a visuo-proprioceptive cue conflict | |
| BDNF增强逆转了颅脑放射治疗引起的认知功能下降和神经退行性后果 | El-Khatib, S. M. | N/A | BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences | |
| 神经网络结构如何改变大脑的自组织临界性 | Sugimoto, Y. A. | N/A | How neural network structure alters the brain's self-organized criticality | |
| 不同类别的抗抑郁药物通常会改变小鼠苍白球的结构和功能 | Abe, Y. | N/A | Distinct classes of antidepressants commonly act to shape pallidal structure and function in mice | |
| 被盗的未来：异常的海马神经发生导致癫痫中产生胶质细胞 | Segasby, T. | N/A | A stolen future: aberrant hippocampal neurogenesis produces glial cells in epilepsy | |
| 缺失但未受糖皮质激素调节的促肾上腺皮质激素释放激素（Crh）调控小鼠的焦虑样行为 | Friedman, H. R. | N/A | Absent, but not glucocorticoid-modulated, corticotropin-releasing hormone (Crh) regulates anxiety-like behaviors in mice | |
| 用于消融兴奋性和抑制性突触的工具箱 | Bareghamyan, A. | N/A | A toolbox for ablating excitatory and inhibitory synapses | |
| 在活体细胞内成像显示，癫痫发作后皮质扩散性去极化期间，内质网钙离子出现耗竭。 | Stern, M. A. | N/A | Organellular imaging in vivo reveals a depletion of endoplasmic reticular calcium during post-ictal cortical spreading depolarization | |
| 高速三维成像与25相机多焦点显微镜 | Hirata-Miyasaki, E. | N/A | High-speed 3D Imaging with 25-Camera Multifocus Microscope | |
| 年龄对静息状态下皮层网络的影响 | Gohil, C. | N/A | Effects of age on resting-state cortical networks | |
| 评估白尾鹿（Odocoileus virginianus）中蜱唾液和中肠细胞外囊泡作为抗蜱疫苗的效果 | Gonzalez Gonzalez, J. | N/A | Evaluation of tick salivary and midgut extracellular vesicles as anti-tick vaccines in White-tailed deer (Odocoileus virginianus) | |
| 鼻内接种CPAF联合环二腺苷酸可诱导记忆性CD4 T细胞反应，并在经阴道感染鼠衣原体后减轻细菌负荷 | Poston, T. B. | N/A | Intranasal immunization with CPAF combined with cyclic-di-AMP induces a memory CD4 T cell response and reduces bacterial burden following intravaginal infection with Chlamydia muridarum | |
| 感知到的压力会加重人体皮肤中的银屑病：来自人源化银屑病小鼠模型的见解 | Zeltzer, A. | N/A | Perceived stress exacerbates psoriasis in human skin in vivo: Insights from a humanized psoriasis mouse model | |
| 啮齿动物PD1的进化指纹使其活性减弱，但增强了对肿瘤的免疫力，相较于人类PD1。 | Masubuchi, T. | N/A | Evolutionary fingerprint in rodent PD1 confers weakened activity and enhanced tumor immunity compared to human PD1 | |
| 鉴定出一种关键的INO2等位基因，可增强工业发酵酵母菌株Saccharomyces cerevisiae的乙醇抗性 | Albillos-Arenal, S. | N/A | Identification of a crucial INO2 allele for enhancing ethanol resistance in an industrial fermentation strain of Saccharomyces cerevisiae | |
| 志贺氏菌通过IpaH1.4介导的RNF213降解逃避LPS泛素化 | Naydenova, K. | N/A | Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213 | |
| 选择性保留北大西洋海洋中的岩藻糖丰富低聚糖 | Bligh, M. | N/A | Selective preservation of fucose-rich oligosaccharides in the North Atlantic Ocean | |
| 时空、环境和行为因素对管理蜜蜂蜂群中瓦螨密度的预测作用 | Boehm Vock, L. | N/A | Spatiotemporal, environmental, and behavioral predictors of Varroa mite intensity in managed honey bee apiaries | |
| 传粉者访问模式和差异性繁殖相容性维持了印度西高止山脉一种夜间开花的姜科植物的苞片颜色多态性 | Shrotri, S. | N/A | Pollinator visitation pattern and differential reproductive compatibilities maintain bract colour polymorphism in a nocturnal ginger from Western Ghats, India | |
| 在孟加拉国亚热带季风气候下的半农村地区，果蝇（双翅目：实蝇科）的种群动态 | Momen, M. | N/A | Population dynamics of fruit flies (Diptera: Tephritidae) in a semirural area under subtropical monsoon climate of Bangladesh | |
| 海洋碳输出可以通过基于海洋颜色的浮游植物群落来预测。 | Kramer, S. J. | N/A | Ocean carbon export can be predicted from ocean color-based phytoplankton communities | |
| 蜂后餐桌上的农民？：蜜蜂（Apis mellifera）在准备蜂群过程中微生物群的动态变化 | Kolasa, M. R. | N/A | Peasants at the queen's table?: The microbiome's dynamics throughout swarming preparation in honey bees (Apis mellifera) | |
| 季节性和年际稳定性在胶状绒紫菜（红藻门）种群遗传结构中的表现 | Shainker-Connelly, S. J. | N/A | Seasonality and inter-annual stability in the population genetic structure of Batrachospermum gelatinosum (Rhodophyta) | |
| 细胞色素P450的自然变异独立于β-微管蛋白，改变了噻菌灵的反应。 | Collins, J. | N/A | Naturally occurring variation in a cytochrome P450 modifies thiabendazole responses independent of beta-tubulin | |
| 利用单细胞eQTL分析鉴定导致代谢功能障碍相关脂肪性肝炎的个体水平变异基因 | Hong, S. E. | N/A | Identification of genes conferring individual-level variation responsible for metabolic dysfunction-associated steatohepatitis using single-cell eQTL analysis | |
| 高阶上位性在大规模蛋白质序列-功能关系中的重要性 | Sethi, P. | N/A | Importance of higher-order epistasis in large protein sequence-function relationships | |
| 单细胞多组学分析揭示了胚胎发育过程中转录与染色质相互作用的原则 | Bhardwaj, V. | N/A | Single-cell multi-omic analysis reveals principles of transcription-chromatin interaction during embryogenesis | |
| 补充膳食纳米锌可通过调节铜锌超氧化物歧化酶表达来赋予更高的抗氧化状态 | Tah, A. | N/A | Supplemental Dietary Nano Zinc Can Impart Higher Antioxidant Status by Modulating Cu-Zn SOD Expression | |
| 细胞收缩力驱动四维生物打印活体构建物的时空形态变化 | Cleveland, D. S. | N/A | Cell Contractile Forces Drive Spatiotemporal Morphing in 4D Bioprinted Living Constructs | |
| 去细胞化细胞外基质（dECM）及其衍生墨水的成分的比较蛋白质组学分析与天然组织相比 | Irastorza, A. | N/A | Comparative proteomic analysis of the composition of decellularized extracellular matrix (dECM) and dECM-based inks as compared to the native tissue | |
| 基于柔性石墨烯的神经技术用于帕金森病大鼠的高精度深脑映射和神经调控 | Ria, N. | N/A | Flexible graphene-based neurotechnology for high-precision deep brain mapping and neuromodulation in Parkinsonian rats | |
| 探索使用贝塔过程先验对贝叶斯生存分析中的基线危险进行灵活惩罚 | Dauda, K. A. | N/A | Exploring the Flexible Penalization of Bayesian Survival Analysis Using Beta Process Prior for Baseline Hazard | |
| 实现单细胞声学定位与去激活超分辨率 | Smith, C. A. B. | N/A | Achieving Single Cell Acoustic Localisation with Deactivation Super Resolution | |
| PhysiofUS：一种基于组织运动的心率和呼吸率评估方法，用于神经功能超声成像 | ZUCKER, N. | N/A | PhysiofUS : a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging | |
| 通过生物树脂分子量调节和多波长光学技术实现的多材料体积生物打印与即插即用悬浮浴生物制造 | Ribezzi, D. | N/A | Multi-material volumetric bioprinting and plug-and-play suspension bath biofabrication via bioresin molecular weight tuning and multiwavelength optics | |
| 超越静态脑图谱：基于人工智能的开放数据库构建与全脑神经形态学动态挖掘 | Jiang, S. | N/A | Beyond Static Brain Atlases: AI-Powered Open Databasing and Dynamic Mining of Brain-Wide Neuron Morphometry | |
| AlphaMut：一种用于建议螺旋破坏性突变的深度强化学习模型 | Bhargav, P. | N/A | AlphaMut: a deep reinforcement learning model to suggest helix-disrupting mutations | |
| 使用高光谱图像和机器学习对虾青素含量进行准确的无创定量 | Calderini, M. | N/A | Accurate non-invasive quantification of astaxanthin content using hyperspectral images and machine learning | |
| 构建面向透明生物医学人工智能的文献知识库 | Huang, Y. | N/A | Building a literature knowledge base towards transparent biomedical AI | |
| AsaruSim：单细胞与空间RNA-Seq纳米孔长读长模拟工作流程 | Hamraoui, A. | N/A | AsaruSim: a single-cell and spatial RNA-Seq Nanopore long-reads simulation workflow | |
| 磷酸化调控的无序核受体的构象多样性与拓扑动力学 | Akulov, V. | N/A | Phosphorylation regulated conformational diversity and topological dynamics of an intrinsically disordered nuclear receptor | |
| RNA G-四链体中肌苷、2'-O-甲基化和N6-甲基腺苷修饰的结构和动态后果：一项分子动力学研究 | Dutta, N. | N/A | Structural and dynamic consequences of inosine, 2'-O-methylation, and N6-methyladenosine modifications in RNA G-quadruplex: A molecular dynamics study | |
| 甲基-CpG结合域蛋白维持表观遗传的机制模型 | Dai, L. | N/A | Mechanistic model for epigenetic maintenance by methyl-CpG-binding domain proteins | |
| 线粒体泛素连接酶MARCHF5与MCL1合作抑制KSHV转化的原发性渗出性淋巴瘤细胞系的凋亡 | Viswanathan, P. | N/A | The Mitochondrial Ubiquitin Ligase MARCHF5 Cooperates with MCL1 to Inhibit Apoptosis in KSHV-Transformed Primary Effusion Lymphoma Cell Lines | |
| 超级增强子分析揭示了ThPOK/ZBTB7B，一种CD4+细胞谱系承诺因子，作为主调控因子，限制乳腺癌细胞呈现管腔非迁移表型。 | Arcuschin, C. D. | N/A | Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4+ cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype | |
| MAX失活会扰乱MYC网络，并在多种组织中诱导神经内分泌肿瘤的形成。 | Freie, B. | N/A | MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues | |
| 肺腺癌对顺铂和培美曲塞化疗耐药现象中Orai3通道和ABC型转运蛋白的特征及意义。 | Daoudi, R. | N/A | Characterization and implication of the Orai3 channel and ABC type transporters in the phenomenon of chemoresistance to cisplatin and pemetrexed in lung cancer. | |
| 头颈部癌症中纳米气泡超声造影剂的异质动力学与血管生成信号传导 | Van Court, B. | N/A | Heterogeneous Kinetics of Nanobubble Ultrasound Contrast Agent and Angiogenic Signaling in Head and Neck Cancer | |
| 血小板中密集但不包含α颗粒的成分对于胰腺β细胞分泌胰岛素是必需的。 | Kolczynska-Matysiak, K. | N/A | Dense but not alpha granules of platelets are required for insulin secretion from pancreatic beta cells | |
| 评估SUBI和DRO1渗入系在不同生长阶段下对淹水和干旱条件的耐受性 | Soe, I. | N/A | Assessing Stress Tolerance of SUBI and DRO1 Introgression lines Under Flooding and Drought Conditions at Different Growth Stages | |
| 过氧化物酶2介导了人类骨骼肌肌管中由收缩活动诱导的氧化磷酸化过程中对氧化还原刺激的适应性变化。 | Heaton, R. A. | N/A | Peroxiredoxin 2 mediates redox-stimulated adaptations to oxidative phosphorylation induced by contractile activity in human skeletal muscle myotubes | |
| 多器官转录组图谱揭示了分娩的特征 | Ni, D. | N/A | Multi-organ transcriptomic atlas reveals hallmarks of labor | |
| 四吡咯生物合成酶的自然变异及其调控机制改变了叶绿素突变体Oy1-N1989的特性。 | Kaur, A. | N/A | Natural variation in tetrapyrrole biosynthetic enzymes and their regulation modify the chlorophyll mutant Oy1-N1989 | |
| 对七种开花植物中选择性剪接、长链非编码RNA和环状RNA的综合注释 | Gabel, A. | N/A | Comprehensive annotations of alternative splicing, lncRNAs, and circRNAs in seven species of flowering plants | |
| 从基因到通路：一种精选基因方法在硬骨鱼转录组学中准确重建通路的应用 | Herrera, M. | N/A | From Genes to Pathways: A Curated Gene Approach to Accurate Pathway Reconstruction in Teleost Fish Transcriptomics | |
| DrugTar通过整合大型语言模型和基因本体论，提升了药物预测能力。 | Borhani, N. | N/A | DrugTar Improves Druggability Prediction by Integrating Large Language Models and Gene Ontologies | |
| 鸡蛋辐照对野生型和沃尔巴克氏体转染的埃及伊蚊蚊媒发育和致育性的影响 | Kittayapong, P. | N/A | Effect of egg irradiation on development and sterility of wild-type and Wolbachia trans-infected Aedes aegypti mosquito vectors | |
| 运动准备在时间决策中追踪决策边界交叉 | Ofir, N. | N/A | Motor preparation tracks decision boundary crossing in temporal decision-making | |
| 淀粉样β蛋白诱导的培养星形胶质细胞中快速局部钙升高的改变 | Nakata, K. | N/A | Amyloid-β-induced Alteration of Fast and Localized Calcium Elevations in Cultured Astrocytes | |
| 为什么我们有这么多兴奋性神经元？ | Wang, Q. | N/A | Why do we have so many excitatory neurons? | |
| CX3CR1 调节常驻小胶质细胞向脑损伤部位的迁移 | Wagner, J. | N/A | CX3CR1 modulates migration of resident microglia towards brain injury | |
| 内源性大麻素2-花生四烯酰甘油通过细胞外微泡按需释放和运输 | Straub, V. M. | N/A | The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles | |
| 阿尔茨海默病小鼠模型中CA1和CA3区位细胞功能的明显紊乱 | Park, S. | N/A | Distinct Disruptions in CA1 and CA3 Place Cell Function in Alzheimer's Disease Mice | |
| 在自由活动的小鼠进行探索行为期间，胡须体感皮层的具身处理 | Gantar, L. | N/A | Embodied processing in whisker somatosensory cortex during exploratory behaviour in freely moving mice | |
| 触须剥夺引发了一种特殊的皮层稳态可塑性，但在Fmr1 KO中这种可塑性受损。 | Lakhani, A. | N/A | Whisker deprivation triggers a distinct form of cortical homeostatic plasticity that is impaired in the Fmr1 KO | |
| 白细胞介素37抗炎复合物的计算建模 | Sardag, I. | N/A | Computational Modeling of the Anti-Inflammatory Complexes of IL37 | |
| A2.CAR Treg与抗CD154联合治疗在小鼠同种异体不匹配心脏移植模型中的疗效及局限性 | Durgam, S. S. | N/A | Efficacy and limitations of combined A2.CAR Treg and anti-CD154 therapy in a mouse model of haplo-mismatched heart transplantation | |
| 母体免疫保护后代免受肠道病毒感染，同时不会对体液免疫记忆产生负面影响。 | Muleta, K. G. | N/A | Maternal immunity protects offspring from enteric viral infection without negatively affecting humoral immune memory | |
| 利用内质网滞留信号工程化CD3亚基促进异基因CAR T细胞生产 | Ebrahimiyan, H. | N/A | Engineering CD3 Subunits with Endoplasmic Reticulum Retention Signal Facilitates Allogeneic CAR T Cell Production | |
| BiMultiNetPlot：一个用于可视化生态二分多层网络的R包 | Li, H.-D. | N/A | BiMultiNetPlot: An R package for visualizing ecological bipartite multilayer networks | |
| 小型哺乳动物及其洞穴塑造了球孢子菌在土壤中的分布：一项长期的生态实验 | Head, J. R. | N/A | Small mammals and their burrows shape the distribution of Coccidioides in soils: a long-term ecological experiment | |
| 趋异选择和可塑性在物种形成初期塑造了生殖隔离 | Jarrett, B. J. M. | N/A | Divergent selection and plasticity shape reproductive isolation at the onset of speciation | |
| 饮食特化推动了雁形目（Anseriformes）在头骨和附肢骨骼上的适应、趋同和整合。 | Chatterji, R. M. | N/A | Dietary specialization drives adaptation, convergence, and integration across the cranial and appendicular skeleton in Waterfowl (Anseriformes). | |
| 古代生物分子表明已灭绝的洞熊具有学习觅食策略 | Meleg, I. N. | N/A | Ancient biomolecules suggest learned foraging strategy in extinct cave bears | |
| 在野生酵母模型中非整倍体回复的速率 | Gasch, A. P. | N/A | On the rate of aneuploidy reversion in a wild yeast model | |
| 全球土壤传播蠕虫的多样性揭示了影响诊断目标的群体偏向性遗传变异 | Papaiakovou, M. | N/A | Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets | |
| Rfam 15：2025年的RNA家族数据库 | Ontiveros-Palacios, N. | N/A | Rfam 15: RNA families database in 2025 | |
| 大规模突变扫描和深度学习的转录抑制域预测与设计 | Valbuena, R. | N/A | Prediction and design of transcriptional repressor domains with large-scale mutational scans and deep learning | |
| 巴巴利猕猴社交信息的化学特征 | Weiss, B. M. | N/A | Chemical signatures of social information in Barbary macaques | |
| 可操控的弹簧带针用于在组织中自主急转弯 | Abdoun, O. | N/A | Steerable Tape-Spring Needle for Autonomous Sharp Turns Through Tissue | |
| STANCE：一种统一的统计模型，用于在空间转录组学中检测细胞类型特异的空间变异基因 | Su, H. | N/A | STANCE: a unified statistical model to detect cell-type-specific spatially variable genes in spatial transcriptomics | |
| 基于OPLS的多类分类与数据驱动的类间关系发现 | Forsgren, E. | N/A | OPLS-based Multiclass Classification and Data-Driven Inter-Class Relationship Discovery | |
| 药物化学中的AI增强R基团探索 | Zhao, H. | N/A | AI-Augmented R-Group Exploration in Medicinal Chemistry | |
| 隐神经刺激对两种不同膀胱状态（活动不足和活动过度）的兴奋和抑制作用 | li, C. | N/A | Excitatory and Inhibitory Effects of Saphenous Nerve Stimulation on Two Different Bladder Conditons: Underactivity and Overactivity | |
| 睡眠期间心率变异性受损：REM睡眠行为障碍、创伤性脑损伤及创伤后应激障碍退伍军人中自主神经功能障碍的早期潜在窗口？ | Cunningham, H. A. | N/A | Heart rate variability impairment during sleep in Veterans with REM sleep behavior disorder, traumatic brain injury, and posttraumatic stress disorder: An early potential window into autonomic dysfunction? | |
| 健康数据科学教育洞察：定性内容分析 | Rohani, N. | N/A | Insights into Health Data Science Education: A Qualitative Content Analysis | |
| 人类溶质载体超家族的代谢图谱 | Wiedmer, T. | N/A | Metabolic mapping of the human solute carrier superfamily | |
| 需要腿部顺应性来解释不同步态中的地面反作用力模式和速度范围。 | Safa, A. T. | N/A | Leg compliance is required to explain the ground reaction force patterns and speed ranges in different gaits | |
| 人类听觉皮层中的时间整合主要与绝对时间相关，而非结构持续时间。 | Norman-Haignere, S. V. | N/A | Temporal integration in human auditory cortex is predominantly yoked to absolute time, not structure duration | |
| Na+/K+-ATPase的生电性给高度活跃的尖峰细胞的计算带来了挑战。 | Weerdmeester, L. | N/A | The electrogenicity of the Na+/K+-ATPase poses challenges for computation in highly active spiking cells | |
| 心脏对听觉不规则性的反应揭示了睡眠期间的分层信息处理 | Koroma, M. | N/A | Cardiac responses to auditory irregularities reveal hierarchical information processing during sleep | |
| microRNA-138-5p在小脑输入层抑制兴奋性突触强度 | Delvendahl, I. | N/A | microRNA-138-5p suppresses excitatory synaptic strength at the cerebellar input layer | |
| TMX1是一种二硫键氧化还原酶，通过调节CD3zeta对T细胞功能至关重要。 | Chai, T. | N/A | TMX1, a disulfide oxidoreductase, is necessary for T cell function through regulation of CD3zeta | |
| CXCL16-CXCR6的进化多样性：爬行动物中的趋同替代和反复基因丢失 | Salve, B. G. | N/A | Evolutionary diversity of CXCL16-CXCR6: Convergent Substitutions and Recurrent Gene Loss in Sauropsids | |
| EGO-1和RRF-1在调控秀丽隐杆线虫生殖系外源RNAi效率中的双重作用 | Dejima, K. | N/A | Dual roles of EGO-1 and RRF-1 in regulating germline exo-RNAi efficiency in Caenorhabditis elegans | |
| 一个支持法国淡水环境中水生大型无脊椎动物DNA条形码分析的注释参考库 | Gauvin, P. | N/A | An annotated reference library for supporting DNA metabarcoding analysis of aquatic macroinvertebrates in French freshwater environments | |
| 对111个鲽形目线粒体基因组的全面分析：结构、保守性、变异及进化的见解 | Tan, S. | N/A | Comprehensive analysis of 111 Pleuronectiformes mitochondrial genomes: insights into structure, conservation, variation and evolution | |
| 利用长读长测序和基因组组装鉴定出Aspergillus wentii的萜类合成酶武器库 | Olumakaiye, R. | N/A | Identification of a terpene synthase arsenal using long-read sequencing and genome assembly of Aspergillus wentii | |
| 人类长非编码RNA的基因组生物学：虚拟核型 | Palma, A. | N/A | Genome biology of long non-coding RNAs in humans: a virtual karyotype | |
| Jaeger：一种准确且快速的深度学习工具，用于检测噬菌体序列 | Wijesekara, Y. | N/A | Jaeger: an accurate and fast deep-learning tool to detect bacteriophage sequences | |
| 通过厚组织的空间转录组学在空间和时间上解卷积器官发生 | Asami, S. | N/A | Deconvolving organogenesis in space and time via spatial transcriptomics in thick tissues | |
| 哺乳动物启动子具有RNA聚合酶II低占用率和高周转率的特点。 | Chatsirisupachai, K. | N/A | Mammalian promoters are characterised by low occupancy and high turnover of RNA polymerase II | |
| 双歧杆菌假链状菌的胶囊性胞外多糖增强了临床前乳腺癌中的全身抗肿瘤免疫 | Price, C. A. | N/A | Bifidobacterium pseudocatenulatum capsular exopolysaccharide enhances systemic anti-tumour immunity in pre-clinical breast cancer | |
| 同时分析克罗恩病和有症状对照组的血液和肠道T细胞和B细胞库，揭示了克罗恩病患者免疫库的组织特异性改变 | Mahdy, A. K. H. | N/A | Simultaneous Profiling of the Blood and Gut T and B Cell Repertoires in Crohn's Disease and Symptomatic Controls Illustrates Tissue-specific Alterations in the Immune Repertoire of Crohn's Disease Patients | |
| 偷听食草动物：使用接触式麦克风量化植物-昆虫相互作用 | Mehrotra, D. | N/A | Eavesdropping on Herbivores: Using contact microphones to quantify Plant-Insect Interactions | |
| 绘制与小麦病原菌Zymoseptoria tritici温度胁迫相关的基因组区域图谱 | Stapley, J. | N/A | Mapping genomic regions associated with temperature stress in the wheat pathogen Zymoseptoria tritici | |
| BRCA1、BRCA2和PALB2变异分类中共同分离分析的综合且易获取模型 | Moghadasi, S. | N/A | A Comprehensive and Accessible Model for Co-Segregation Analysis in BRCA1, BRCA2, and PALB2 Variant Classification | |
| dScaff - 一个基于参考基因组数据，用于自动搭建从头组装草图的生物信息学框架 | Constantin, N. D. | N/A | dScaff - an automatic bioinformatics framework for scaffolding draft de novo assemblies based on reference genome data | |
| 艺术X的相机路径、建模及图像处理工具 | Ermel, U. H. | N/A | Camera Paths, Modeling, and Image Processing Tools for ArtiaX | |
| 肝细胞中线粒体复合体III功能的恢复突显了肝脏作为独立于棕色脂肪细胞激活的关键产热器官的作用。 | Banerjee, R. | N/A | Restoration of mitochondrial complex III function in hepatocytes highlights the liver as a key thermogenic organ independent of brown adipocyte activation | |
| 探索记忆性景观：双曲几何揭示物体概念记忆中的层次结构 | Lee, F. M. | N/A | Navigating Memorability Landscapes: Hyperbolic Geometry Reveals Hierarchical Structures in Object Concept Memory | |
| 来自ADHD诱导的多能干细胞（iPSC）模型的多巴胺能神经元的转录组分析 | Namipashaki, A. | N/A | Transcriptome profiling of dopaminergic neurons derived from an ADHD induced pluripotent stem cell (iPSC) model | |
| 评估秘鲁塔克纳地区土壤中潜在有毒元素及其由环境责任引发的潜在生态风险 | Caceda Quiroz, C. J. | N/A | Evaluation of Potentially Toxic Elements in Soil and Potential Ecological Risks Generated by Environmental Liabilities in Tacna, Peru | |
| 对用于人口控制的自我限制遗传控制策略的比较评估 | Han, Y. | N/A | A comparative assessment of self-limiting genetic control strategies for population suppression | |
| 通过基于针的腔扩张方法捕获的生物材料演化特性 | Varner, H. M. | N/A | Evolving properties of biological materials captured via needle-based cavity expansion method | |
| 模仿机制：肉类与肉类替代品的比较 | St. Pierre, S. R. | N/A | Mimicking mechanics: A comparison of meat and meat analogs | |
| 高通量实证与虚拟筛选发现乳腺癌中多倍体巨型癌细胞的新型抑制剂 | Ma, Y. | N/A | High-Throughput Empirical and Virtual Screening to Discover Novel Inhibitors of Polyploid Giant Cancer Cells in Breast Cancer | |
| 具有独立调控粘附配体迁移率和粘弹性的水凝胶可增强细胞粘附和扩展 | Moghaddam, A. S. | N/A | Hydrogels with Independently Controlled Adhesion Ligand Mobility and Viscoelasticity Increase Cell Adhesion and Spreading | |
| 通过氧化苯酚偶联在细胞上共价结合生物材料，通过细胞内生物物理编程调节干细胞命运 | Johnbosco, C. | N/A | Covalent on-cell conjugation of biomaterials through oxidative phenolic coupling regulates stem cell fate via intracellular biophysical programming | |
| scParadise：可调节的高精度多任务细胞类型注释与表面蛋白丰度预测 | Chechekhina, E. | N/A | scParadise: Tunable highly accurate multi-task cell type annotation and surface protein abundance prediction | |
| 残留物替代对蛋白质细胞丰度的影响 | Schulze, T. K. | N/A | Effects of residue substitutions on the cellular abundance of proteins | |
| 核小体定位和聚合物力学解释了100千碱基尺度的基因组接触 | Corrette, J. | N/A | Nucleosome placement and polymer mechanics explain genomic contacts on 100kbp scales | |
| 丙戊酸对髓母细胞瘤中干细胞和分化调节因子的调控 | Freire, N. H. | N/A | Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma | |
| 破表者：基于微孔阵列的微型胸腺类器官模型的建立，适用于高通量应用。 | Major, V. | N/A | Watch-breaker: establishment of a microwell array-based miniaturized thymic organoid model suitable for high throughput applications. | |
| 通过在三维培养中使用倾向神经转录因子刺激人类视网膜的再生能力 | Wohlschlegel, J. | N/A | Stimulating the regenerative capacity of the human retina with proneural transcription factors in 3D cultures | |
| 空间结构对崎岖适应性景观中早期和长期适应的影响 | Servajean, R. | N/A | Impact of spatial structure on early and long-term adaptation in rugged fitness landscapes | |
| 斑胸草雀距离呼叫声学特征的依赖于情境的调制：来自一种新颖的目标导向发声范式的见解 | Safarcharati, Z. | N/A | Context-Dependent Modulations in Acoustic Features of Zebra Finch Distance Calls: Insights from a Novel Goal-Directed Vocalization Paradigm | |
| 斑马鱼视锥视蛋白光谱位移的分子机制 | Chi, L. A. | N/A | Molecular Mechanisms Underlying the Spectral Shift in Zebrafish Cone Opsins | |
| 在多稳态知觉过程中，观察者会经历哪些感知类别？ | Skerswetat, J. | N/A | Which perceptual categories do observers experience during multistable perception? | |
| 通过DynamicNeuronTracker揭示了单个化学感觉神经元对外部刺激的小鼠组织切片组合反应性 | Noh, J. | N/A | Combinatorial responsiveness of single chemosensory neurons to external stimulation of mouse explants revealed by DynamicNeuronTracker | |
| Akap11 突变小鼠（一种精神分裂症和双相情感障碍的遗传模型）中，突触PKA活性升高以及纹状体多巴胺信号传导异常。 | Song, B. J. | N/A | Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder | |
| 人背根神经节中端细胞的转录组学和组织学特征 | Haberberger, R. V. | N/A | Transcriptomic and histological characterization of telocytes in the human dorsal root ganglion | |
| 睡眠剥夺小鼠大脑皮层细胞特异性转录组和核蛋白组的整合分析 | Jha, P. K. | N/A | An integrative analysis of cell-specific transcriptomics and nuclear proteomics of sleep-deprived mouse cerebral cortex | |
| 从诱导多能干细胞发展而来的内皮向造血转变的发育调控 | Wellington, R. | N/A | Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells | |
| 动态转录和表观遗传变化定义了出生后肌腱的生长 | Dingwall, H. L. | N/A | Dynamic transcriptional and epigenetic changes define postnatal tendon growth | |
| 动态BMP信号调节斑马鱼中生骨节的诱导和谱系多样化 | Xie, L. | N/A | Dynamic BMP signaling regulates sclerotome induction and lineage diversification in zebrafish | |
| 一种优化用于生长和发育的果蝇全营养饮食 | Sorge, S. | N/A | A Drosophila holidic diet optimised for growthand development | |
| Api-TRACE：一种用于在受限环境中追踪蜜蜂的系统，旨在研究蜜蜂学习过程及锂对学习的影响 | Erdem, B. | N/A | Api-TRACE: A System for Honey Bee Tracking in a Constrained Environment to Study Bee Learning Process and the Effect of Lithium on Learning | |
| 语音解码能力与左侧弓状束的纤维密度在阅读发展的纵向过程中存在关联。 | Perdue, M. V. | N/A | Phonological decoding ability is associated with fiber density of the left arcuate fasciculus longitudinally across reading development | |
| 脂肪细胞代谢状态调节胶质细胞吞噬功能 | Rajan, A. | N/A | Adipocyte metabolic state regulates glial phagocytic function | |
| 在一种可调控TDP-43的小鼠模型中，超兴奋性先于CA3海马神经退行性变，该模型模拟了ALS-FTD（肌萎缩侧索硬化-额颞叶痴呆）。 | Rodemer, W. | N/A | Hyperexcitability precedes CA3 hippocampal neurodegeneration in a dox-regulatable TDP-43 mouse model of ALS-FTD. | |
| BrainScale：在脉冲神经网络中实现可扩展的在线学习 | Wang, C. | N/A | BrainScale: Enabling Scalable Online Learning in Spiking Neural Networks | |
| Pdgfab/Pdgfra介导的趋化作用引导了来自肌节衍生的成纤维细胞前体在斑马鱼中的迁移 | Mendez-Olivos, E. E. | N/A | Pdgfab/Pdgfra-mediated chemoattraction guides the migration of sclerotome-derived fibroblast precursors in zebrafish | |
| # BioRxiv 2024-09-23 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 多感官序列预测背后的振荡多时间尺度机制 | Wang, P. | N/A | Oscillatory multi-timescale mechanisms underlying multisensory sequence prediction | |
| 使用“AngioTag”斑马鱼在体内分析内皮翻译组 | Miller, M. F. | N/A | Profiling the endothelial translatome in vivo using 'AngioTag' zebrafish | |
| 基于探索的学习稳定控制器预测运动适应 | Seethapathi, N. | N/A | Exploration-based learning of a stabilizing controller predicts locomotor adaptation | |
| 损伤后存活的DA SN神经元中Kv4.3介导的节律性可塑性与全内源性放电范围的恢复相关 | Kovacheva, L. | N/A | Recovery of the full in vivo firing range in post-lesion surviving DA SN neurons associated with Kv4.3-mediated pacemaker plasticity | |
| 超越梯度：干扰和泛化的分解、几何控制 | Scott, D. N. | N/A | Beyond gradients: Factorized, geometric control of interference and generalization | |
| 微卫星密度图谱展示了完整参考人类基因组中的短串联重复聚集情况 | Xia, Y. | N/A | Microsatellite Density Landscapes Illustrate Short Tandem Repeats Aggregation in The Complete Reference Human Genome | |
| 通过多步行者监督分子动力学（mwSuMD）解决的隐藏GPCR结构转变 | Deganutti, G. | N/A | Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD) | |
| 快速解聚和纤毛蛋白的力学敏感性支持在网格蛋白介导的内吞作用中快速周转 | Mousavi, S. I. | N/A | Fast actin disassembly and fimbrin mechanosensitivity support rapid turnover during clathrin-mediated endocytosis | |
| 等压交联质谱技术用于研究蛋白质及其复合物的构象和结构变化 | Ranish, J. | N/A | Isobaric crosslinking mass spectrometry technology for studying conformational and structural changes in proteins and complexes | |
| 铁死亡整合线粒体功能障碍和病理性炎症以促进肺动脉高压 | Kazmirczak, F. | N/A | Ferroptosis Integrates Mitochondrial Derangements and Pathological Inflammation to Promote Pulmonary Hypertension | |
| 改进的排列检验方法能够在非平稳时间序列的重复次数有限的情况下，检测出它们之间的依赖关系。 | Yuan, A. E. | N/A | Improved permutation tests enable detection of dependence between nonstationary time series despite limited numbers of replicates | |
| 改进的排列检验方法能够在非平稳时间序列之间检测到依赖关系，即使重复次数有限。 | Yuan, A. E. | N/A | Improved permutation tests enable detection of dependence between nonstationary time series despite limited numbers of replicates | |
| NEURD 提供连接组学的自动校对和特征提取功能。 | Celii, B. | N/A | NEURD offers automated proofreading and feature extraction for connectomics | |
| mosna揭示了不同类型的细胞相互作用，这些相互作用可预测对免疫疗法的反应和癌症中的生存情况。 | Coullomb, A. | N/A | mosna reveals different types of cellular interactions predictive of response to immunotherapies and survival in cancer | |
| PAPET：从PacBio SequelII数据中识别5-甲基胞嘧啶的高效算法集合 | Groux, R. | N/A | PAPET: a collection of performant algorithms to identify 5-methyl cytosine from PacBio SequelII data | |
| 皮质回路中实时学习的神经最小作用原理 | Senn, W. | N/A | A neuronal least-action principle for real-time learning in cortical circuits | |
| 将生物相互作用纳入生态位分析中，揭示了小丑鱼群落组成的模式 | Garcia, A. | N/A | Integrating Biotic Interactions In Niche Analyses Unravels Patterns Of Community Composition in Clownfishes | |
| 逆转弱碱性药物的质子化作用极大地增强了其细胞内扩散，并减少了溶酶体的隔离。 | DEY, D. | N/A | Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration | |
| METASPACE-ML：利用机器学习进行成像质谱的特定背景代谢物注释 | Wadie, B. | N/A | METASPACE-ML: Context-specific metabolite annotation for imaging mass spectrometry using machine learning | |
| 睡眠依赖性记忆过程中RNA加工基因的调控 | Li, Y. | N/A | Modulation of RNA processing genes during sleep-dependent memory | |
| 肌纤维特异性敲除TGF-β I型受体可引发肌肉肥大，并促进肌肉收缩和氧化代谢。 | Shi, A. | N/A | Myofibre-specific knockout of TGF-β type I receptors triggers muscle hypertrophy and promotes contraction and oxidative metabolism | |
| 人的知识在独立的大脑系统中分别通过外向参照系和内向参照系进行独立编码。 | Chavez, R. S. | N/A | Person knowledge is independently encoded by allocentric and egocentric reference frames within separate brain systems | |
| 物体、面孔和空间：个体行为差异所体现的视觉物体知觉的组织原则 | Sigurdardottir, H. M. | N/A | Objects, faces, and spaces: Organizational principles of visual object perception as evidenced by individual differences in behavior | |
| CENP-E通过对抗Aurora激酶来促进端对端附着，从而启动染色体排列。 | Vukusic, K. | N/A | CENP-E initiates chromosome congression by opposing Aurora kinases to promote end-on attachments | |
| BioMANIA：通过对话简化生物信息学数据分析 | Dong, Z. | N/A | BioMANIA: Simplifying bioinformatics data analysis through conversation | |
| 锌指同源盒-3（ZFHX3）调控视交叉上核中全基因组的每日基因表达 | Bafna, A. | N/A | Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus | |
| Epiregulon：推断单细胞转录因子活性以预测药物反应和细胞状态的驱动因素 | Wlodarczyk, T. | N/A | Epiregulon: Inference of single-cell transcription factor activity to predict drug response and drivers of cell state | |
| 药物输送的动力学决定了细菌对抗生素反应的进化过程 | Crow, J. C. | N/A | Dynamics of drug delivery determines course of evolution of antibiotic responses in bacteria | |
| 在14特斯拉场强下进行高分辨率清醒小鼠功能性磁共振成像 | Hike, D. | N/A | High-resolution awake mouse fMRI at 14 Tesla | |
| eMOSAIC：多模态分布外不确定性量化简化了大规模多药理学研究 | Badkul, A. | N/A | eMOSAIC: Multi-modal Out-of-distribution Uncertainty Quantification Streamlines Large-scale Polypharmacology | |
| 昼夜节律神经肽PDF对活动节律具有性别二态性效应 | Iyer, A. R. | N/A | The Circadian Neuropeptide PDF has Sexually Dimorphic Effects on Activity Rhythms | |
| 模拟安大略湖近岸与离岸水交换 | Hlevca, B. | N/A | Modeling nearshore-offshore water exchange in Lake Ontario | |
| 灵长类大脑尺寸/身体尺寸关系中进化滞后的重要性 | Dunbar, R. I. M. | N/A | Significance of Evolutionary Lags in the Primate Brain Size/Body Size Relationship | |
| 一种通用且有效的去条纹变分方法：应用于光片显微镜、聚焦离子束扫描电镜和遥感图像 | Rottmayer, N. | N/A | A universal and effective variational method for destriping: application to light-sheet microscopy, FIB-SEM and remote sensing images | |
| Hill-Robertson干扰可能会影响对高度自交物种中新突变适应性效应的推断 | Daigle, A. | N/A | Hill-Robertson interference may bias the inference of fitness effects of new mutations in highly selfing species | |
| 在视觉受损的大脑中，从感官到知觉的盲文字母表征的转变 | Haupt, M. | N/A | The transformation of sensory to perceptual braille letter representations in the visually deprived brain | |
| 保护计划下小种群基因组多样性的趋势：以两种法国鸡品种为例的研究 | Bortoluzzi, C. | N/A | Trends in genome diversity of small populations under a conservation program: a case study of two French chicken breeds | |
| 高效生成蛋白质口袋的工具——PocketGen | Zhang, Z. | N/A | Efficient Generation of Protein Pockets with PocketGen | |
| 在情景记忆的形成和回忆过程中，显著网络、默认模式网络和前顶叶网络的电生理动力学：一项多实验的iEEG重复研究 | Das, A. | N/A | Electrophysiological dynamics of salience, default mode, and frontoparietal networks during episodic memory formation and recall: A multi-experiment iEEG replication | |
| 基因背景和发育状态对胶质母细胞瘤患者来源细胞信号通路及治疗反应的影响 | Berezovsky, A. D. | N/A | Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells | |
| 使用TREAT和otter分析长读长测序平台上的串联重复复杂性 | Tesi, N. | N/A | Characterising tandem repeat complexities across long-read sequencing platforms with TREAT and otter | |
| 转录组学和跨细胞器互补揭示了12-cis-oxo-植物二烯酸在受伤的拟南芥中有限的信号传导能力 | Mekkaoui, K. | N/A | Transcriptomics and trans-organellar complementation reveal a limited signaling capacity of 12-cis-oxo-phytodienoic acid in wounded Arabidopsis | |
| 从背外侧前额叶皮质的转录组和表观组数据推断女性阿尔茨海默病患者的多种疾病进展路径的可能性 | Honda, K. | N/A | Possibilities of multiple disease progression pathways in female Alzheimer's disease patients inferred from transcriptome and epigenome data of the dorsolateral prefrontal cortex | |
| 专家导航员采用基于合理复杂性的决策优先级排序，用于大规模现实世界规划 | Fernandez Velasco, P. | N/A | Expert Navigators Deploy Rational Complexity-Based Decision Prioritization for Large-Scale Real-World Planning | |
| 寄生在非洲慈鲷鱼上的桡足类寄生虫Ergasilus kandti的线粒体基因组、系统发育位置及分布更新 | Jansen, D. | N/A | Mitogenomics, phylogenetic position, and updated distribution of Ergasilus kandti, an ergasilid copepod parasitizing African cichlid fishes | |
| 活细胞荧光显微镜 - 高通量图像与数据分析的端到端工作流程 | Zahumensky, J. | N/A | Live Cell Fluorescence Microscopy - An End-to-End Workflow for High-Throughput Image and Data Analysis | |
| MRAP2 修饰黑皮质素-4受体的信号传导和寡聚化状态。 | Sohail, I. | N/A | MRAP2 modifies signaling and oligomerization state of the melanocortin-4 receptor | |
| G蛋白偶联受体激酶2（GRK2）调控毛囊稳态 | Asensio, A. | N/A | The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis | |
| 定义表观遗传抑制对肺癌细胞反应的异质分子图谱 | Lin, C. | N/A | Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition | |
| 预测肺移植后原发性移植物功能障碍：基于机器学习的生物标志物发现 | Nord, D. | N/A | Predicting Primary Graft Dysfunction in Lung Transplantation: Machine Learning-Guided Biomarker Discovery | |
| 在已发现的癌症驱动核苷酸（CDNs）中——基因、癌症类型和患者之间的分布情况 | Zhang, L. | N/A | On the discovered Cancer Driving Nucleotides (CDNs)-Distributions across genes, cancer types and patients | |
| 大规模重复进化与癌症驱动核苷酸（CDNs）完全鉴定的理论 | Zhang, L. | N/A | The theory of massively repeated evolution and full identifications of Cancer Driving Nucleotides (CDNs) | |
| PhyloFunc：作为元蛋白质组数据分析中一种新型生态学指标的系统发育功能距离 | Wang, L. | N/A | PhyloFunc: Phylogeny-informed Functional Distance as a New Ecological Metric for Metaproteomic Data Analysis | |
| 原噬菌体与铜绿假单胞菌临床分离株的抗生素耐药性关联不频繁 | Chang, T. H. | N/A | Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates | |
| 大麻二酚与益生菌的协同作用可以抑制血糖指标，增强胰岛素分泌，并缓解2型糖尿病的症状。 | Naeini, S. E. | N/A | The synergy between cannabidiol and probiotics curtails the glycemic indicators, enhances insulin production, and alleviates the symptoms of type 2 diabetes. | |
| 多囊卵巢综合征小鼠模型中的GnRH脉冲发生器活性 | Zhou, Z. | N/A | GnRH pulse generator activity in mouse models of polycystic ovary syndrome | |
| 一种类人轮廓整合的前馈机制 | Doshi, F. R. | N/A | A feedforward mechanism for human-like contour integration | |
| 多发性硬化进展中的性别差异单细胞图谱 | Soler-Saez, I. | N/A | Single cell landscape of sex differences in the progression of multiple sclerosis | |
| 选择针对不同手性RNA元件的氟化适配体 | Dantsu, Y. | N/A | Selection of Fluorinated Aptamer Targeting RNA Element with Different Chirality | |
| 巨蜂鸟（Patagona spp.）（鸟类：蜂鸟科）的分类学、命名法及鉴定 | Williamson, J. L. | N/A | Taxonomy, nomenclature, and identification of the giant hummingbirds (Patagona spp.) (Aves: Trochilidae) | |
| 构建镜像RNA纳米结构以增强生物稳定性和药物递送效率 | Zhang, Y. | N/A | Construction of mirror-image RNA nanostructure for enhanced biostability and drug delivery efficiency | |
| 基因功能在随机基因沉默的瞬间被揭示 | Gupta, S. | N/A | Gene Function Revealed at the Moment of Stochastic Gene Silencing | |
| 桡足类化学信号对两种拟菱形藻细胞内和细胞外毒素的影响 | Pourdanandeh, M. | N/A | Effects of copepod chemical cues on intra- and extracellular toxins in two species of Dinophysis | |
| 最近的研究表明，气味体验能够有选择性地调节小鼠嗅球中嗅觉敏感度，这种调节作用跨越了嗅球中的小球输出层。 | Subramanian, N. | N/A | Recent odor experience selectively modulates olfactory sensitivity across the glomerular output in the mouse olfactory bulb | |
| 线粒体叶酸代谢紊乱会导致线粒体DNA泄漏，并激活细胞凋亡或炎症通路。 | Hwang, S. | N/A | Disruption of mitochondrial folate metabolism leads to mitochondrial DNA leakage and activation of apoptotic or inflammatory pathways | |
| 质粒病毒维持使细菌种群从感染中恢复并实现病毒-细菌共存 | Sanchez-Martinez, R. | N/A | Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence | |
| 大肠杆菌细胞中DnaA和DNA的相对分布及其表型变异性的因素 | Namboodiri, S. K. | N/A | Relative Distribution of DnaA and DNA in Escherichia coli Cells as a Factor of Their Phenotypic Variability | |
| 在肢体发育过程中，En1的时间表达错误会导致不同的表型。 | Ringel, A. R. | N/A | Temporal misexpression of En1 during limb development causes distinct phenotypes | |
| 一类新的受体：脂质通过其膜锚定物调节哺乳动物Gsα刺激的腺苷酸环化酶活性 | Landau, M. | N/A | A new class of receptors: Lipids regulate mammalian Gsalpha-stimulated adenylyl cyclase activities via their membrane anchors | |
| 通过一种具有可解释注意力单元的新型深度学习模型探索核定位信号宇宙 | Li, Y. | N/A | Discovering nuclear localization signal universe through a novel deep learning model with interpretable attention units | |
| 网格蛋白介导的内吞作用中的囊泡化途径 | Wang, X. | N/A | Vesiculation pathways in clathrin-mediated endocytosis | |
| 乳腺癌上皮-间充质转化及器官特异性转移中三维基因组结构的重新排列 | Das, P. | N/A | Rearrangement of 3D genome organization in breast cancer epithelial - mesenchymal transition and metastasis organotropism | |
| 人类从腹侧壳核到运动皮层区域的假定开环电路的解离研究 I：高分辨率连接组学 | Rizor, E. J. | N/A | Dissociation of putative open loop circuit from ventral putamen to motor cortical areas in humans I: high-resolution connectomics | |
| 评估生理指标在通过比较问题测试（CQT）检测欺骗和真实性中的应用 | Rashid, A. M. S. | N/A | Evaluating Physiological Indicators in Detecting Deception and Truthfulness using theComparison Question Test (CQT) | |
| DNMT1介导的抑制性中间神经元迁移调控影响皮层结构和功能 | Reichard, J. | N/A | DNMT1-Mediated Regulation of Inhibitory Interneuron Migration Impacts Cortical Architecture and Function | |
| 转录调控因子HcpR的全长结构及其与血红素的结合 | Belvin, B. R. | N/A | Full-length structure and heme binding in the transcriptional regulator HcpR | |
| 肌动蛋白丝切割和封端的机制：凝溶胶蛋白的作用 | Barrie, K. R. | N/A | Mechanism of Actin Filament Severing and Capping by Gelsolin | |
| 神经内分泌通过果蝇血管壁龛调控肠道再生 | Medina, A. | N/A | Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila. | |
| 神经营养因子artemin及其受体GFRα3通过离子通道TRPM8介导偏头痛样疼痛。 | Yang, C. | N/A | The neurotrophic factor artemin and its receptor GFRα3 mediate migraine-like pain via the ion channel TRPM8 | |
| 通过考虑树突计算来克服运动传感器模型的局限性 | Luna, R. | N/A | Overcoming the limitations of motion sensor models by considering dendritic computations | |
| 海马体中人口活动的稀疏性在三突触回路和背腹轴上与任务无关。 | Lee, J. Q. | N/A | Sparsity of population activity in the hippocampus is task-invariant across the trisynaptic circuit and dorsoventral axis | |
| 在斑马鱼胚胎中，快肌纤维的生长与Mylpf剂量的增加成比例 | Adekeye, T. E. | N/A | Fast-twitch myofibrils grow in proportion to Mylpf dosage in the zebrafish embryo | |
| 机器学习时代的整合建模：HADDOCK策略在CAPRI第47至55轮中的总结 | Reys, V. | N/A | Integrative modeling in the age of machine learning: a summary of HADDOCK strategies in CAPRI rounds 47-55 | |
| 用于结构系统发育学的通用替换矩阵。 | Garg, S. G. | N/A | A general substitution matrix for structural phylogenetics. | |
| 探索同步的边缘：在行为中的猴子中，皮层活动短暂地滑入慢波 | Pazienti, A. | N/A | Probing The Edge Of Synchronization: Cortical Activity Transiently Slips Into Slow Waves In Behaving Monkeys | |
| 从DNA序列预测和功能解析染色体间基因组结构的双胞胎方法 | Jha, A. | N/A | Prediction and functional interpretation of inter-chromosomal genome architecture from DNA sequence with TwinC | |
| 来自精神分裂症个体的hiPSC衍生的星形胶质细胞促进了类似小胶质细胞的吞噬作用和趋化性的改变 | Cardozo, P. L. | N/A | hiPSC-derived astrocytes from individuals with schizophrenia promote alterations in phagocytosis and chemotaxis of microglial-like cells | |
| 使用神经网络解决巴布亚新几内亚人口的非洲起源事件 | Mondal, M. | N/A | Resolving out of Africa event for Papua New Guinean population using neural network | |
| BCR交联有选择性地抑制IgE类别转换重组 | Wade-Vallance, A. K. | N/A | BCR ligation selectively inhibits IgE class switch recombination | |
| 寄生传播时间选择塑造了宿主冈比亚按蚊的转录反应，并提示免疫逃避 | Silva, L. M. | N/A | Selection on time to parasite transmission shapes the host Anopheles gambiae transcriptional response and suggests immune evasion | |
| scooby：在单细胞分辨率下从DNA序列建模多模态基因组特征 | Hingerl, J. C. | N/A | scooby: Modeling multi-modal genomic profiles from DNA sequence at single-cell resolution | |
| 环节动物组蛋白基染色质调控的演化与发展动力 | Martin-Zamora, F. M. | N/A | The evolution and developmental dynamics of histone-based chromatin regulation in Annelida | |
| 地下动物的隐花色素-1（Cryptochrome-1）中反复出现的突变，改变了行为和分子层面的昼夜节律。 | Swaminathan, A. | N/A | A repeatedly evolved mutation in Cryptochrome-1 of subterranean animals alters behavioral and molecular circadian rhythms | |
| 苜蓿（Medicago truncatula）中的CORYNE基因调控花序分生组织分支、营养信号传递以及丛枝菌根共生关系 | Orosz, J. | N/A | Medicago truncatula CORYNE regulates inflorescence meristem branching, nutrient signaling, and arbuscular mycorrhizal symbiosis | |
| 田间作物转录组模型通过在系统控制的环境中的测量得到了增强 | Hashida, Y. | N/A | Field-crop transcriptome models are enhanced by measurements in systematically controlled environments | |
| 多病虫抗性番茄品系对白粉虱传播病毒TYLCV积累的响应 | Prabhakar, S. S. | N/A | The response of multi-disease and insect-resistant tomato lines to the accumulation of TYLCV, a whitefly-transmitted virus | |
| PEBP1 增强线粒体功能障碍引发的整合应激反应 | Cheng, L. | N/A | PEBP1 amplifies mitochondrial dysfunction induced integrated stress response | |
| 定义不同代谢条件下人类脂肪组织的血管龛 | AlZaim, I. | N/A | Defining the Vascular Niche of Human Adipose Tissue Across Metabolic Conditions | |
| LINE1促进核内区室化以抑制胚胎干细胞中的8细胞状态 | Zhang, J. | N/A | LINE1 promotes nuclear compartmentalization to repress the 8-cell state in embryonic stem cells | |
| BEDMS：一种基因组区域属性元数据标准化工具 | Tambe, S. | N/A | BEDMS: A metadata standardizer for genomic regionattributes | |
| 矮牵牛杂交种的染色体水平基因组组装与注释 | Saei, A. | N/A | Chromosome-level Genome Assembly and Annotation of Petunia hybrida | |
| 早期生活不可预测性对青少年海马和杏仁核对新奇刺激反应的性别特异性影响 | Davis, E. P. | N/A | Sex-specific effects of early life unpredictability on hippocampal and amygdala responses to novelty in adolescents | |
| 不饱和脂质作为控制穴样内陷形成和解体的关键因素 | Wu, Y. | N/A | Unsaturated lipids as key control points for caveola formation and disassembly | |
| 瞬时Notch激活将多能干细胞衍生的心肌细胞转化为浦肯野纤维命运 | Gonzalez, D. M. | N/A | Transient Notch Activation Converts Pluripotent Stem Cell-Derived Cardiomyocytes towards a Purkinje Fiber Fate | |
| 动态系统理论指导下的细胞分化景观学习 | Howe, A. E. S. | N/A | Dynamical systems theory informed learning of cellular differentiation landscapes | |
| 物种共现模型的样本量考虑。 | Cowans, A. | N/A | Sample size considerations for species co-occurrence models. | |
| 温度与资源之间的相互作用如何从种群扩展到群落 | Kremer, C. T. | N/A | How interactions between temperature and resources scale from populations to communities | |
| 严格（在）验证生态模型 | Song, C. | N/A | Rigorous (in)validation of ecological models | |
| 杂合缺失对拟南芥表型变化及剂量补偿的影响 | Ikoma, T. | N/A | Effect of heterozygous deletions on phenotypic changes and dosage compensation in Arabidopsis thaliana | |
| 比较泛基因组学揭示了临床相关成员在镰刀菌属物种复合体中的不同适应性 | Brassington, P. J. | N/A | Comparative pan-genomics reveals divergent adaptations in clinically-relevant members of the Fusarium solani species complex | |
| 探索单细胞数据中的群体特异性技术变异模式 | Zhou, Y. | N/A | Exploring group-specific technical variation patterns of single-cell data | |
| PoreVision：一种用于提升扫描电镜孔隙分析效率和准确性的程序 | Olevsky, L. M. | N/A | PoreVision: A Program for Enhancing Efficiency and Accuracy in SEM Pore Analyses | |
| DiffPaSS - 使用软分数进行高性能可微蛋白质序列配对 | Lupo, U. | N/A | DiffPaSS - High-performance differentiable pairing of protein sequences using soft scores | |
| 通过表征学习和稀疏模型发现探索生物系统的控制方程 | Sadria, M. | N/A | Discovering Governing Equations of Biological Systems through Representation Learning and Sparse Model Discovery | |
| GuaCAMOLE：GC偏倚感知估计提高了宏基因组物种丰度的准确性 | Holcik, L. | N/A | GuaCAMOLE: GC-bias aware estimation improves the accuracy of metagenomic species abundances | |
| 揭示半乳糖凝集素-1与脂质膜结合的GM1特异性 | Scollo, F. | N/A | Unraveling the GM1 specificity of Galectin-1 binding to lipid membranes | |
| 扩展自动化多构象配体建模至大环化合物和片段 | Flowers, J. | N/A | Expanding Automated Multiconformer Ligand Modeling to Macrocycles and Fragments | |
| 没有基因振荡器或外部驱动的生物振荡 | Vandenbroucke, V. | N/A | Biological oscillations without genetic oscillator or external forcing | |
| 一种新型方法用于在单细胞分辨率下表征细胞间相互作用，揭示了感染期间血液T细胞-单核细胞复合物的独特特征 | Kang, N. | N/A | A novel method for characterizing cell-cell interactions at single-cell resolution reveals unique signatures in blood T cell-monocyte complexes during infection | |
| FcγR和CD9依赖的丘脑突触吞噬小胶质细胞驱动皮层脑损伤后的认知障碍 | Matoba, K. | N/A | FcγR- and CD9-dependent synapse engulfing microglia in the thalamus drives cognitive impairment following cortical brain injury | |
| 溶酶体LRRC8复合物调节溶酶体pH值、形态及全身葡萄糖代谢 | Kumar, A. | N/A | Lysosomal LRRC8 complex regulates lysosomal pH, morphology and systemic glucose metabolism | |
| 磷脂酶D的辅助域调控其在果蝇光感受器中的定位和活性 | Naik, A. | N/A | The accessory domains of Phospholipase D regulate its localization and activity in Drosophila photoreceptors | |
| 线粒体移植：适应性生物增强 | Lu, X. | N/A | Mitochondrial Transplantation: Adaptive Bio-enhancement | |
| 在裂殖酵母中，细胞质内的扩散随着细胞大小的增加而增加。 | Tan, C. | N/A | Intracellular diffusion in the cytoplasm increases with cell size in fission yeast | |
| 幼稚多能性退出包含一个由脂质代谢引发的基因组完整性检查点。 | de Souza, R. A. | N/A | The exit of naïve pluripotency contains a lipid metabolism-induced checkpoint for genome integrity. | |
| 内共生体以温度依赖的方式影响瓢虫对蚜虫的捕食率 | Thomsen, K. B. | N/A | Endosymbionts impact ladybird predation rates of aphids in a temperature-dependent manner | |
| 日均温度可以比速率累加更好地预测疟疾传播的热限。 | Shocket, M. S. | N/A | Mean daily temperatures can predict the thermal limits of malaria transmission better than rate summation | |
| 传统品种环境数据在气候适应型玉米育种中的应用 | Li, F. | N/A | The utility of environmental data from traditionalvarieties for climate-adaptive maize breeding | |
| 不同衬纸材料和浸液对埃及伊蚊（双翅目：蚊科）雌蚊产卵偏好的影响 | Momen, M. | N/A | Effect of different lining paper materials and infusions on oviposition preference of Aedes aegypti (Diptera: Culicidae) gravid mosquitoes | |
| Msp1介导的脂质双层中底物提取的能量需求和机制可塑性 | Smith, B. | N/A | Energetic requirements and mechanistic plasticity in Msp1-mediated substrate extraction from lipid bilayers | |
| SMART MRS：一种用于GABA编辑磁共振波谱（MRS）的模拟MEGA-PRESS伪影工具箱 | Bugler, H. | N/A | SMART MRS: A Simulated MEGA-PRESS Artifacts Toolbox for GABA-edited MRS | |
| 人类NDPK六聚体结构、稳定性和相互作用的动态建模 | Lim, Y. Y. | N/A | Modelling dynamics of human NDPK hexamer structure, stability and interactions | |
| 用于监测Cas9核酸内切酶活性的固态纳米孔实时检测 | Chau, C. C. | N/A | Solid-State Nanopore Real Time Assay for Monitoring Cas9 Endonuclease Reactivity | |
| 浓缩LiCl水溶液中DNA的性质表明向C-DNA的转变 | Mazur, A. | N/A | Properties of DNA in concentrated aqueous solutions of LiCl suggest transition to C-DNA | |
| 宫内生长受限对发育中的胰腺免疫系统的影响 | Golden, T. N. | N/A | The effect of intrauterine growth restriction on the developing pancreatic immune system | |
| CanDrivR-CS：一种用于区分复发性和罕见变异的癌症特异性机器学习框架 | Francis, A. | N/A | CanDrivR-CS: A Cancer-Specific Machine Learning Framework for Distinguishing Recurrent and Rare Variants | |
| TBX15调控脂肪组织中免疫应答基因网络，并改变杂合敲除小鼠的脂肪质量和脂肪库重量 | Zolkiewski, L. | N/A | TBX15 regulates a network of immune response genes in adipose tissue and alters fat mass and depot weight in heterozygous knockout mice | |
| 一种一步法协议，用于制备适用于原位活细胞应用和超分辨率成像的不透光荧光HaloTag底物 | Rossmann, K. | N/A | A one-step protocol to generate impermeable fluorescent HaloTag substrates for in situ live cell application and super-resolution imaging | |
| PointTree：单神经元长程轴突投射的自动精确重建 | Cai, L. | N/A | PointTree: Automatic and accurate reconstruction of long-range axonal projections of single-neuron | |
| 弥合秀丽隐杆线虫的连接组与全脑活动之间的差距 | Creamer, M. S. | N/A | Bridging the gap between the connectome and whole-brain activity in C. elegans | |
| 构建小鼠大脑树突微环境的图谱有助于发现解剖布局、投射目标和神经元转录组特征之间的潜在关联。 | Liu, Y. | N/A | Constructing a Mouse Brain Atlas of Dendritic Microenvironments Helps Discover Hidden Associations Between Anatomical Layout, Projection Targets and Transcriptomic Profiles of Neurons | |
| Tau P301S转基因小鼠出现步态和眼球运动障碍，类似于进行性核上性麻痹 | Creed, R. B. | N/A | Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy | |
| 低强度聚焦超声参数在人类神经调控中的研究 | Ennasr, A. | N/A | Examination of low-intensity focused ultrasound parameters for human neuromodulation | |
| 视觉体验评估工具：一种用于量化视觉体验的近视研究仪器 | Sullivan, D. | N/A | The Visual Experience Evaluation Tool: A Myopia Research Instrument for Quantifying Visual Experience | |
| SAPAP3小鼠模型在强迫症发病前的特征：行为、神经可塑性及裸盖菇素治疗 | Lazar, M. | N/A | Premorbid Characteristics of the SAPAP3-Mouse Model of Obsessive-Compulsive Disorder: Behavior, Neuroplasticity, and Psilocybin Treatment | |
| TWINKLE：一款用于教学和研究的开源双光子显微镜 | Schottdorf, M. | N/A | TWINKLE: An open-source two-photon microscope for teaching and research | |
| 鼠标爪：逆转翻译FINGER多模态生活方式干预增强了成年野生型雌性小鼠的突触可塑性和认知能力 | Alanko, V. | N/A | Mouse PAW: reverse-translating the FINGER multimodal lifestyle intervention enhances synaptic plasticity and cognition in adult wild type female mice | |
| 成年神经发生和焦虑的自然变异预测近交系小鼠的等级地位 | Grieco, F. | N/A | Natural variations of adult neurogenesis and anxiety predict hierarchical status of inbred mice | |
| PHluorin-偶联的次级纳米抗体作为测量突触小泡胞外和胞内吞吐的工具 | Georgiev, S. V. | N/A | PHluorin-conjugated secondary nanobodies as a tool for measuring synaptic vesicle exo- and endocytosis | |
| 不同体型动物的前馈和反馈控制性能受感觉运动延迟和肌肉力量能力限制的影响 | Mohamed Thangal, S. N. | N/A | Effects of sensorimotor delays and muscle force capacity limits on the performance of feedforward and feedback control in animals of different sizes | |
| 嗅觉和三叉神经途径的HSV-1中枢神经系统感染与区域性小胶质细胞异质性 | Niemeyer, C. | N/A | Olfactory and Trigeminal Routes of HSV-1 CNS Infection with Regional Microglial Heterogeneity | |
| 在语言产生和理解过程中，额叶-颞叶皮层中与语音声音特异性一致的脑信号。 | Dmitrieva, X. | N/A | Congruent brain signatures specific to speech sounds in fronto-temporal cortex during language production and understanding. | |
| 女性一生中的全脑动态与激素变化：从生殖阶段到更年期过渡及之后 | Escrichs, A. | N/A | Whole-brain dynamics and hormonal shifts throughout women's lifespan: From reproductive stages to menopausal transition and beyond | |
| 新生小鼠在出现觅食和饮水行为之前，饥饿和口渴的神经表征具有显著差异 | Wang, D. C. | N/A | Distinct Neural Representations of Hunger and Thirst in Neonatal Mice before the Emergence of Food- and Water-seeking Behaviors | |
| 创伤性脑损伤加剧了酒精摄入和神经炎症，同时伴随着认知功能和胆碱能活性的下降。 | Gangal, H. | N/A | Traumatic Brain Injury Exacerbates Alcohol Consumption and Neuroinflammation with Decline in Cognition and Cholinergic Activity | |
| 音乐才能调节皮层（而非脑干）对音乐三和弦处理中注意力的影响 | MacLean, J. | N/A | Musicianship modulates cortical (but not brainstem) effects of attention on processing musical triads | |
| 广泛的大脑活动增加与意识受损的额叶癫痫发作有关 | Salardini, E. | N/A | Widespread brain activity increases in frontal lobe seizures with impaired consciousness | |
| 神经几何学有效地表示了灵长类基底神经节中价值和模态的抽象形式。 | Kim, H. F. | N/A | Neural geometry efficiently representing abstract form of value and modality in the primate basal ganglia | |
| 神经几何学有效地表示了灵长类基底神经节中价值和模态的抽象形式。 | Hwang, S.-H. | N/A | Neural geometry efficiently representing abstract form of value and modality in the primate basal ganglia | |
| 经济选择中神经编码的理性注意力不足 | Fine, J. M. | N/A | Rational inattention in neural coding for economic choice | |
| 人类胚胎类器官形态空间的可解释图谱揭示了原肠胚形成失败模式并预测了致畸物 | Rufo, J. | N/A | An explainable map of human gastruloid morphospace reveals gastrulation failure modes and predicts teratogens | |
| 访客对灵长类动物救助中心黑猩猩（Pan troglodyte）行为的影响 | Maurer, S. | N/A | Visitor effect on the behavior of chimpanzees (pan troglodyte) at a primate rescue center | |
| 内质网应激转录因子Luman/CREB3通过激活未折叠蛋白反应和胆固醇生物合成途径，是施万细胞存活和髓鞘形成能力的新型调控因子。 | Verge, V. M. K. | N/A | The ER stress transcription factor Luman/CREB3 is a novel regulator of Schwann cell survival and myelinating capacity through the activation of the unfolded protein response and cholesterol biosynthesis pathways | |
| 胆碱能神经元活动通过毒蕈碱信号传导促进弥漫性中线胶质瘤的生长 | Monje, M. | N/A | Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling | |
| 神经选择性的系统性变化反映了类别诊断维度所获得的重要性。 | Luthra, S. | N/A | Systematic changes in neural selectivity reflect the acquired salience of category-diagnostic dimensions | |
| 产后环境富集可纠正成年小鼠早期逆境暴露导致的神经周围网形成缺陷及反转学习障碍 | Jamwal, S. | N/A | Postnatal Enrichment Corrects Deficits in Perineuronal Net Formation and Reversal Learning in Adult Mice Exposed to Early Adversity | |
| 利用连续时间转移熵估计器推断脉冲神经元的有效网络 | Shorten, D. | N/A | Inferring Effective Networks of Spiking Neurons Using a Continuous-Time Estimator of Transfer Entropy | |
| AKT介导的TSC2磷酸化调控刺激和组织特异性mTORC1信号传导及器官生长 | Cormerais, Y. | N/A | AKT-mediated phosphorylation of TSC2 controls stimulus and tissue-specific mTORC1 signaling and organ growth | |
| Bnip3lb驱动的线粒体自噬维持了胚胎造血干细胞池的扩增 | Meader, E. | N/A | Bnip3lb-driven mitophagy sustains expansion of the embryonic hematopoietic stem cell pool | |
| 间充质-上皮转变减少了肿瘤球体的增殖，但增加了免疫逃逸 | Dimari, G. | N/A | Mesenchymal-epithelial transition reduces proliferation but increases immune evasion in tumor spheroids | |
| 脱嘧啶/脱嘌呤核酸内切酶2（APEX2/APE2）在人胚胎干细胞中对TERT的高效表达是必需的。 | Stern, J. L. | N/A | Apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2/APE2) is required for efficient expression of TERT in human embryonic stem cells. | |
| 内核膜磷酸酶复合物对TGF-β/SMAD信号的抑制作用 | Ji, Z. | N/A | Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex | |
| 细胞信号通过Rac和WAVE介导的机制，将Arp2/3复合物从基底侧招募到顶端，从而促进顶端收缩。 | Zhang, P. | N/A | Cell signaling facilitates apical constriction by basolaterally recruiting Arp2/3 via Rac and WAVE | |
| 空间多组学揭示胰腺癌免疫治疗病理反应者中与三级淋巴结构相关的肿瘤内体液免疫微环境 | Sidiropoulos, D. N. | N/A | Spatial multi-omics reveal intratumoral humoral immunity niches associated with tertiary lymphoid structures in pancreatic cancer immunotherapy pathologic responders | |
| 机器学习驱动的SARS-CoV-2适应性景观模拟 | Durumeric, A. E. P. | N/A | Machine Learning Driven Simulations of SARS-CoV-2 Fitness Landscape | |
| 肠道微生物群昼夜振荡节律的丧失与动脉粥样硬化的进展相关 | Zhang, H. | N/A | Loss of Diurnal Oscillatory Rhythms in Gut Microbiota Correlates with Progression of Atherosclerosis | |
| 在植物体内转座子测序用于鉴定Xylella fastidiosa中的毒力基因 | Burbank, L. P. | N/A | In planta transposon sequencing for virulence gene identification in Xylella fastidiosa | |
| 肠球菌属粪肠球菌菌株中β-内酰胺耐药性的进化轨迹 | Ugalde-Silva, P. | N/A | Evolutionary trajectories of β-lactam resistance in Enterococcus faecalis strains | |
| 在考古牙齿结石中鉴定古代抗生素抗性基因 | Standeven, F. | N/A | Identifying ancient antibiotic resistance genes in archaeological dental calculus | |
| 在铜绿假单胞菌拮抗作用下，脓肿分枝杆菌的持续存在 | Gupta, R. | N/A | Mycobacterium abscessus persistence in the face of Pseudomonas aeruginosa antagonism | |
| 胞外多糖聚N-乙酰葡萄糖胺（PNAG）在体内覆盖肺炎克雷伯菌。 | Bradshaw, J. | N/A | The exopolysaccharide Poly-N-Acetyl-Glucosamine (PNAG) coats Klebsiella pneumoniae in vivo | |
| 一种膜结合的传送带控制着细菌第9型分泌系统的旋转方向 | Shrivastava, A. | N/A | A membrane-associated conveyor belt controls the rotational direction of the bacterial type 9 secretion system | |
| 与炎症性肠病相关的肠埃希菌菌株侵袭性的遗传和微生物分析 | Kim, J. | N/A | Genetic and microbial analysis of invasiveness for Escherichia coli strains associated with inflammatory bowel disease | |
| 群体感应通过依赖和不依赖于第六型分泌系统的机制调控霍乱弧菌中的平行细胞死亡途径 | Mashruwala, A. A. | N/A | Quorum sensing orchestrates parallel cell death pathways in Vibrio cholerae via Type 6 secretion dependent and independent mechanisms | |
| 粪便滤液转移对坏死性小肠结肠炎的防护作用需要供体活病毒组的存在 | Spiegelhauer, M. R. | N/A | Protection against necrotizing enterocolitis by fecal filtrate transfer requires an active donor virome | |
| 鼻内接种的雪貂在急性期和急性后期阶段，SARS-CoV-2的神经侵袭性和神经毒力潜能 | Benavides, F. F. W. | N/A | Neuroinvasive and neurovirulent potential of SARS-CoV-2 in the acute and post-acute phase of intranasally inoculated ferrets | |
| 利用工程改造的甲烷嗜甲基菌（Methanosarcina acetivorans）从一碳化合物中生产倍半萜类化合物巴索贝内烯（bisabolene） | Mentrup, A. | N/A | Production of the sesquiterpene bisabolene from one-carbon compounds in an engineered Methanosarcina acetivorans | |
| Pythia：非随机DNA修复使得CRISPR/Cas9整合和基因编辑具有可预测性 | Naert, T. | N/A | Pythia: Non-random DNA repair allows predictable CRISPR/Cas9 integration and gene editing | |
| TNFSF13 不足会破坏人类结肠上皮细胞介导的 B 细胞分化 | Ma, X. | N/A | TNFSF13 insufficiency disrupts human colonic epithelial cell-mediated B cell differentiation | |
| SGLT2抑制剂通过非CaMKII依赖的机制，对糖尿病心肌病和心房颤动具有保护作用。 | Severino, A. | N/A | SGLT2 inhibitors protect against diabetic cardiomyopathy and atrial fibrillation through a CaMKII independent mechanism | |
| MTALTCO1：一种由线粒体DNA编码的259个氨基酸长的替代蛋白，挑战了传统线粒体基因组学的理解。 | Robitaille, F. | N/A | MTALTCO1: a 259 amino acid long mtDNA-encoded alternative protein that challenges conventional understandings of mitochondrial genomics. | |
| 蛋白质语言模型：规模化是必要的吗？ | Fournier, Q. | N/A | Protein Language Models: Is Scaling Necessary? | |
| 百日咳毒素抗体中和作用的结构基础 | Goldsmith, J. A. | N/A | Structural Basis for Antibody Neutralization of Pertussis Toxin | |
| 在阿尔茨海默病中，Tau蛋白及其他聚集蛋白中发现脱水氨基酸及其交联结构 | Markovich, S. W. | N/A | Discovery of dehydroamino acids and their crosslinks in Tau and other aggregating proteins of Alzheimers disease | |
| 一种综合建模方法用于线粒体嵴 | Brown, C. M. | N/A | An integrative modelling approach to the mitochondrial cristae | |
| 肠道微生物组时代的人类非靶向代谢组学：乙醇与甲醇 | Zuffa, S. | N/A | Human untargeted metabolomics in the gut microbiome era: ethanol vs methanol | |
| 肝源性醛糖还原酶驱动类似Warburg效应的代谢重编程，促进胰岛素抵抗、脂肪肝和肥胖 | Song, D. | N/A | Hepatic aldose reductase drives a Warburg effect-like metabolic reprogramming to promote insulin resistance, fatty liver and obesity | |
| 一种用于Caldimonas thermodepolymerans的初始基因编辑工具集，这是首个嗜热聚羟基烷酸生产模型的代表。 | Grybchuk-Ieremenko, A. | N/A | An initial genome editing toolset for Caldimonas thermodepolymerans, the first model of thermophilic polyhydroxyalkanoates producer | |
| 准确的超大规模基因组集多序列比对 | Lai, X. | N/A | Accurate Multiple Sequence Alignment of Ultramassive Genome Sets | |
| 设计一种基于细胞内适配体的荧光生物传感器，用于追踪大肠杆菌的负担 | Grob, A. | N/A | Design of an intracellular aptamer-based fluorescent biosensor to track burden in E. coli | |
| 建筑给排水系统影响饮用水微生物群的微多样性和群落构建。 | He, H. | N/A | Building plumbing influences the microdiversity and community assembly of the drinking water microbiome. | |
| 针对宿主转录因子HSF1可阻止人巨细胞病毒在体外和体内的复制 | Biswas, J. | N/A | Targeting the host transcription factor HSF1 prevents human cytomegalovirus replication in vitro and in vivo | |
| CLCC1促进疱疹病毒核输出过程中的膜融合。 | Dai, B. | N/A | CLCC1 promotes membrane fusion during herpesvirus nuclear egress. | |
| 间歇性高频有氧-缺氧循环扰动提高废水处理过程中N2O还原酶活性 | Zhou, X. | N/A | Intermittent Perturbation with High-Frequency Aerobic-Anoxic Cycling Enhances N2O Reductase Activity during Wastewater Treatment | |
| 铜绿假单胞菌PAO1的b型鞭毛蛋白糖基结构解析 | Hensbergen, P. J. | N/A | Elucidation of the glycan structure of the b-type flagellin of Pseudomonas aeruginosa PAO1 | |
| 百日咳博德特氏菌的一种新型粘附素是其侵入上皮细胞的关键 | Gollan, M. | N/A | A Novel Adhesin of B. pertussis is Key to Colonisation of Epithelial Cells | |
| CHAMP1复合体指导异染色质组装并促进同源定向DNA修复。 | D'Andrea, A. D. | N/A | CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair | |
| 基于CRISPR的转录激活系统中激活子表达的细胞毒性 | Maddineni, A. | N/A | Cytotoxicity of Activator Expression in CRISPR-based Transcriptional Activation Systems | |
| 适用于原代干细胞多模式CRISPR基因编辑的多功能细胞穿透肽 | Graham, J. P. | N/A | Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells | |
| PDZ介导的底物招募是PP1-Neurabin特异性去磷酸化4E-BP1的主要决定因素。 | Fedoryshchak, R. O. | N/A | PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1dephosphorylation by PP1-Neurabin | |
| 海马体对替代可能性的表征是灵活生成的，以满足认知需求。 | Comrie, A. E. | N/A | Hippocampal representations of alternative possibilities are flexibly generated to meet cognitive demands | |
| 母子二元互动塑造了儿童的社会大脑和心智理论 | Li, L. | N/A | Mother-child dyadic interactions shape children's social brain and theory of mind | |
| 肾上腺素能信号调控星形胶质细胞对神经递质的反应性及对神经活动的控制 | Guttenplan, K. A. | N/A | Adrenergic signaling gates astrocyte responsiveness to neurotransmitters and control of neuronal activity | |
| 主要精神疾病的人类神经发育模型中GABA能神经元失调 | Guo, Z. | N/A | GABAergic neuron dysregulation in a human neurodevelopmental model for major psychiatric disorders | |
| 罗马殖民与迁徙时期对伊比利亚半岛人口的差异性影响。 | Carrion, P. | N/A | Disparate demographic impacts of the Roman Colonization and the Migration Period in the Iberian Peninsula. | |
| # BioRxiv 2024-09-22 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 传导机制在冷温度下对不同外周器官的鼠三叉神经和迷走神经节神经元的影响 | Gers-Barlag, K. | N/A | Transduction mechanisms for cold temperature in mouse trigeminal and vagal ganglion neurons innervating different peripheral organs | |
| 从组学数据集中数据驱动的提取人类激酶-底物关系 | Maier, B. D. | N/A | Data-driven extraction of human kinase-substrate relationships from omics datasets | |
| 利用合成聚合物探究脂质力机制 | Jacobs, M. L. | N/A | Probing the force-from-lipid mechanism with synthetic polymers | |
| 自我信念的力量：成长型思维通过中皮层功能共激活和动态重构促进认知发展 | Zhao, Y. | N/A | Power of self-belief: Growth mindset fosters cognitive development via mesocortical functional coactivation and dynamic reconfiguration | |
| 多巴胺神经元在果蝇嗅觉记忆中具有不同的、急性的功能，驱动吸引和厌恶 | Mohammad, F. | N/A | Dopamine neurons that inform Drosophila olfactory memory have distinct, acute functions driving attraction and aversion | |
| 有齿鲸基因的分子进化揭示了在不同环境中回声定位的适应性 | Magpali, L. | N/A | Molecular evolution of toothed whale genes reveals adaptations to echolocating in different environments | |
| 植物乳杆菌和八角提取物抑制单纯疱疹病毒和水疱性口炎病毒增殖与诱导MX基因表达相关 | Elebeedy, D. | N/A | Inhibition of Herpes simplex virus and Vesicular stomatitis virus Proliferation by Lactiplantibacillus planterum and star anise Extract Is Associated with Induction of MX gene expression | |
| Spanve：一种用于在大规模空间转录组数据中检测下游友好型空间变异基因的统计方法 | Cai, G. | N/A | Spanve: A Statistical Method for Detecting Downstream-Friendly Spatially Variable Genes in Large-Scale Spatial Transcriptomic Data | |
| 自噬体膜连接的重构揭示了Atg11结合膜的能力对线粒体自噬的重要性。 | Andhare, D. | N/A | Reconstitution of autophagosomal membrane tethering reveals that the ability of Atg11 to bind membranes is important for mitophagy. | |
| 所有CDKN2A错义变体的功能表征及其与致病性计算机模型的比较 | Kimura, H. | N/A | Functional characterization of all CDKN2A missense variants and comparison to in silico models of pathogenicity | |
| 使用Neuropixels探针在猕猴初级视觉皮层中进行高分辨率层级识别 | Zhang, L. A. | N/A | High-Resolution Laminar Identification in Macaque Primary Visual Cortex Using Neuropixels Probes | |
| 加压素1a受体拮抗剂破坏了大嘴乌鸦通过三重共居形成的雄性间亲和关系 | Seguchi, A. | N/A | Vasopressin 1a receptor antagonist disrupts male-male affiliative relationships formed by triadic cohabitation in large-billed crows | |
| 磁共振经济学：在全脑关联研究中平衡样本量与扫描时长 | Ooi, L. Q. R. | N/A | MRI economics: Balancing sample size and scan duration in brain wide association studies | |
| 线粒体呼吸图谱揭示了线粒体功能在性别和年龄上的差异变化 | Sarver, D. C. | N/A | Mitochondrial respiration atlas reveals differential changes in mitochondrial function across sex and age | |
| 内源性过氧化氢正向调节肠道衍生肽的分泌，在秀丽隐杆线虫的氧化应激反应中增强神经内分泌作用 | Jia, Q. | N/A | Endogenous hydrogen peroxide positively regulates secretion of a gut-derived peptide in neuroendocrine potentiation of the oxidative stress response in C. elegans | |
| 使用单细胞转录组学对细胞周期状态和类似静止的G0状态进行分类 | O'Connor, S. A. | N/A | Classifying cell cycle states and a quiescent-like G0 state using single-cell transcriptomics | |
| 空间转录组学在骨力学生物学中的应用：探索空间组学时代骨折愈合的力学调控。 | Mathavan, N. | N/A | Spatial Transcriptomics in Bone Mechanomics: Exploring the Mechanoregulation of Fracture Healing in the Era of Spatial Omics. | |
| 人类侧隔核神经元的转录组特征分析揭示了跨物种保守和分化的标记基因 | Phillips, R. A. | N/A | Transcriptomic characterization of human lateral septum neurons reveals conserved and divergent marker genes across species | |
| 将代谢建模与成像结合用于筛选结直肠癌的治疗靶点 | Tavakoli, N. | N/A | Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer | |
| 系统性遗传表征人类PKR激酶结构域突显其功能可塑性，以逃避痘病毒底物模拟 | Chambers, M. J. | N/A | Systematic genetic characterization of the human PKR kinase domain highlights its functional malleability to escape a poxvirus substrate mimic | |
| 由于Vsx2位点上的LacZ敲入/敲出等位基因，导致小眼症和视网膜发育紊乱 | Napoli, F. R. | N/A | Microphthalmia and disrupted retinal development due to a LacZ knock-in/knock-out allele at the Vsx2 locus | |
| 去卷积化的甲基化图谱可区分密切相关的黑色素细胞痣 | Aldea, D. | N/A | Deconvoluted methylation profiles discriminate between closely related melanocytic nevi | |
| 植物交配系统的进化动力学：研究“有趣”植物繁殖系统的偏见可能会适得其反 | Meyer, E. M. | N/A | The evolutionary dynamics of plant mating systems: how bias for studying 'interesting' plant reproductive systems could backfire | |
| 人类尿液微生物群的短期和中期时间变异性：一项观察性队列研究 | Tlaskal, V. | N/A | Short- and mid-term temporal variability of the human urinary microbiota: an observational cohort study | |
| 通过超结构扩展显微镜技术，绘制犬视网膜感光细胞纤毛和杯状突起的蛋白质分布图 | Takahashi, K. | N/A | Mapping protein distribution in the canine photoreceptor sensory cilium and calyceal processes by ultrastructure expansion microscopy | |
| VirID：超越病毒发现——综合平台助力全面RNA病毒特征研究 | Yang, Z. | N/A | VirID: Beyond Virus Discovery - An Integrated Platform for Comprehensive RNA Virus Characterization | |
| cGAS-STING通路在急性缺血诱导的骨髓中性粒细胞生成和中性粒细胞激活中起关键作用 | Zhu, J. | N/A | The cGAS-STING Pathway Is Essential in Acute Ischemia-Induced Neutropoiesis and Neutrophil Priming in the Bone Marrow | |
| 通过巨胞饮作用减少顶端大小可缓解组织拥挤 | Bresteau, E. | N/A | Apical Size Reduction by Macropinocytosis Alleviates Tissue Crowding | |
| 生长率驱动的建模揭示了表型适应如何驱动BRAFV600E突变型黑色素瘤的药物抗性 | Hamis, S. | N/A | Growth rate-driven modelling reveals how phenotypic adaptation drives drug resistance in BRAFV600E-mutant melanoma | |
| 由RhoA特异性GEF ARHGEF17介导的反馈调节调控肌动肌球蛋白网络的解聚 | Rao, V. | N/A | Feedback regulation by the RhoA-specific GEF ARHGEF17 regulates actomyosin network disassembly | |
| 微生物种群几乎从未按逻辑增长，也从未按次线性增长。 | Camacho-Mateu, J. | N/A | Microbial populations hardly ever grow logistically and never sublinearly | |
| 将条形码测序技术应用于提高恶性疟原虫遗传筛选的通量和复杂性 | Muhwezi, A. | N/A | Application of barcode sequencing to increase the throughput and complexity of Plasmodium falciparum genetic screening | |
| 通过血管壁龛的神经内分泌调控果蝇肠道再生。 | Medina, A. | N/A | Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila. | |
| 通过SpaHDmap对空间转录组数据进行可解释的高分辨率降维 | Tang, J. | N/A | Interpretable high-resolution dimension reduction of spatial transcriptomics data by SpaHDmap | |
| 针对癌症相关糖基化进行胃肠道和妇科癌症的过继T细胞治疗 | Zingg, A. | N/A | Targeting cancer-associated glycosylation for adoptive T cell therapy of gastro-intestinal and gynecological cancers | |
| 利用活体叶片切片成像技术分析C4植物叶肉细胞中依赖于束鞘细胞的叶绿体运动 | Kato, Y. | N/A | Bundle sheath cell-dependent chloroplast movement in mesophyll cells of C4 plants analyzed using live leaf-section imaging | |
| 使用质粒分析服务进行高效且成本效益高的长读长扩增子测序：应用于日本牵牛花中的转座子插入等位基因 | Nakagawa, S. | N/A | Labor- and cost-effective long-read amplicon sequencing using a plasmid analysis service: Application to transposon-inserted alleles in Japanese morning glory | |
| 聚焦镓离子束的生物体积电子显微镜依赖于在断面形成辐射抗性富镓层。 | Yang, Z. | N/A | Biological volume EM with focused Ga ion beam depends on formation of radiation-resistant Ga-rich layer at block face | |
| BrainUnit：将物理单位融入高性能AI驱动的科学计算 | Wang, C. | N/A | BrainUnit: Integrating Physical Units into High-Performance AI-Driven Scientific Computing | |
| 出生后前六个月大脑网络的空间发展 | Seraji, M. | N/A | Spatial Development of Brain Networks During The First Six Postnatal Months | |
| 白腿虾养殖生产力的微生物组决定因素 | Shan, X. | N/A | Microbiome determinants of productivity in whiteleg shrimp aquaculture | |
| 授粉者Eristalis tenax中固有花卉偏好的消失 | Rajan, D. H. | N/A | Extinction of innate floral preferences in the pollinator Eristalis tenax | |
| 从头设计的别构可调蛋白纤维的成核限制组装与极性生长 | Shen, H. | N/A | Nucleation limited assembly and polarized growth of a de novo-designed allosterically modulatable protein filament | |
| 使用神经网络解决巴布亚新几内亚人口的“走出非洲”事件 | Mondal, M. | N/A | Resolving out of Africa event for Papua New Guinean population using neural network | |
| 高风险神经精神性拷贝数变异与人类脑细胞中趋同的转录组变化相关 | Dugan, G. | N/A | High-risk neuropsychiatric copy number variants are associated with convergent transcriptomic changes in human brain cells | |
| miR-92a目标RBFOX2的过早上调劫持了PTBP剪接并损害了皮层神经元的分化。 | Weissbach, S. | N/A | Premature upregulation of miR-92a's target RBFOX2 hijacks PTBP splicing and impairs cortical neuronal differentiation. | |
| 从一百万个单倍体基因组中估算人口统计学和突变率 | Schraiber, J. G. | N/A | Estimation of demography and mutation rates from one million haploid genomes | |
| 在恒定条件下实验室小鼠发情周期的季节性变化 | Reichard, T. M. | N/A | Seasonality of the estrus cycle in laboratory mice under constant conditions | |
| 在编码稀疏基因组的物种中，使用两步法从群体基因组数据推断人口统计和选择历史：以人类数据为例的应用 | Soni, V. | N/A | Inferring demographic and selective histories from population genomic data using a two-step approach in species with coding-sparse genomes: an application to human data | |
| 第15组苗前除草剂对除草剂抗性和非抗性黑麦草的生长、表皮蜡质成分及脂肪酸代谢产生不同影响 | Blyth, H. R. | N/A | Group 15 Pre-emergent Herbicides Differentially Effect Plant Growth, Cuticular Wax Composition, and Fatty Acid Metabolism in Herbicide-Resistant and Herbicide-naïve Blackgrass | |
| 调节β-连环蛋白对促进巨噬细胞中WNT表达和减轻肠道损伤具有重要意义。 | Chugh, R. M. | N/A | Modulation of β-Catenin is important to promote WNT expression in macrophages and mitigate intestinal injury | |
| 表观遗传调控网络的扩展和多样化奠定了陆地植物进化过程中重大转变的基础 | Petroll, R. | N/A | The expansion and diversification of epigenetic regulatory networks underpins major transitions in the evolution of land plants | |
| 广谱反应性抗VHH抗体用于表征、阻断或激活基于纳米抗体的CAR-T细胞 | McComb, S. | N/A | Broadly Reactive Anti-VHH Antibodies for Characterizing, Blocking, or Activating Nanobody-Based CAR-T Cells | |
| 自然杀伤细胞功能在妊娠和肿瘤进展过程中受TGF-β信号通路的调控。 | Yalin, A. | N/A | Natural killer cell function is regulated by TGF-β signaling in pregnancy and tumor progression | |
| TSTA：基于线程和SIMD的梯形成对/多序列比对方法 | Peiyu, Z. | N/A | TSTA: Thread and SIMD-Based Trapezoidal Pairwise/Multiple Sequence Alignment Method | |
| 乳腺癌细胞系中非组蛋白赖氨酸甲基化位点及赖氨酸去甲基化酶的定量分析 | Berryhill, C. A. | N/A | Quantitative analysis of non-histone lysine methylation sites and lysine demethylases in breast cancer cell lines | |
| 单核细胞衍生的细胞而非小胶质细胞在神经炎症中引起氧化组织损伤 | Villar-Vesga, J. | N/A | Monocyte-derived cells but not Microglia cause Oxidative Tissue Damage in Neuroinflammation | |
| 发育期和成年期饮食的加性和情境依赖性效应及其在杂交果蝇群体中对生活史特征及其关联的影响 | Chandrakanth, M. | N/A | Additive and context-dependent effects of developmental and adult diet on life-history traits and their associations in outbred Drosophila melanogaster population | |
| 用于研究药物载体和细菌通过活体黏膜屏障传输的人体中流体肠道模型 | Wang, C.-M. | N/A | Human Mesofluidic Intestinal Model for Studying Transport of Drug Carriers and Bacteria Through a Live Mucosal Barrier | |
| 可及的染色质区域和DNA甲基化调控基因表达，导致芸苔属异源三倍体杂种的农艺性状发生变化 | Cheng, D. | N/A | Accessible chromatin regions and DNA methylation regulate gene expression leading to changes in agronomic traits in Brassica allotriploid hybrids | |
| 聚合溶酶体靶向嵌合体：无需共用溶酶体靶向受体的胞外靶向蛋白降解 | Lu, R. H.-H. | N/A | Polymeric Lysosomal-Targeting Chimeras: Extracellular Targeted Protein Degradation Without Co-opting Lysosome-Targeting Receptors | |
| 在常染色体隐性多囊肾病中，升高Gli3的逆转并未改变囊肿的形成。 | Russell, L. G. | N/A | Reversal of elevated Gli3 in Autosomal Recessive Polycystic Kidney Disease does not alter cystogenesis | |
| 与摄食、先天免疫和行为调节相关的扁形动物分泌细胞类型 | Mayorova, T. D. | N/A | Placozoan secretory cell types implicated in feeding, innate immunity and regulation of behavior | |
| 微妙平衡的导航：点突变作弊病毒破坏病毒复制周期 | Meir, M. | N/A | Navigating a fine balance: point-mutant cheater viruses disrupt the viral replication cycle | |
| Tbx4缺失影响出生后肺发育并易导致肺动脉高压。 | Maldonado-Velez, G. | N/A | Loss of Tbx4 Affects Postnatal Lung Development and Predisposes to Pulmonary Hypertension. | |
| MutLgamma 在拟南芥中强制执行减数分裂交叉。 | Durand, S. | N/A | MutLgamma enforces meiotic crossovers in Arabidopsis thaliana | |
| 开发并广泛测序了一个广泛认可的“瓶中基因组”匹配的肿瘤-正常配对样本，用于体细胞基准测试。 | McDaniel, J. H. | N/A | Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair for somatic benchmarks | |
| 叉头框F1在肺动脉高压病理生物学中的作用 | Gomez-Arroyo, J. | N/A | Role of Forkhead box F1 in the Pathobiology of Pulmonary Arterial Hypertension | |
| 开发一种小分子表观遗传再生疗法。通过皮下注射含有高剂量塞布他汀和视黄酸的海藻酸盐制剂，可促进组织生长、血管化和神经支配，并诱导广泛的表观遗传重编程。 | Slonimska, P. | N/A | Development of a small-molecule epigenetic regenerative therapy. Subcutaneous administration of alginate formulations with high loads of zebularine and retinoic acid promotes tissue growth, vascularization and innervation and induces extensive epigenetic repatterning | |
| 统一表型本体（uPheno）：一个跨物种整合表型学的框架 | Matentzoglu, N. | N/A | The Unified Phenotype Ontology (uPheno): A framework for cross-species integrative phenomics | |
| 局部方法计算蛋白质构象中立体化学的影响 | da Rocha, W. | N/A | Influence of stereochemistry in a local approach for calculating protein conformations | |
| 卤化胆固醇改变了三元脂质膜的相行为 | Mehta, D. | N/A | Halogenated cholesterol alters the phase behavior of ternary lipid membranes | |
| 研究新型血液处理方法以增强非小细胞肺癌生物标志物的鉴定 | Karsten, E. | N/A | Investigating the use of novel blood processing methods to boost the identification of biomarkers of non-small cell lung cancer | |
| Gli2 过表达改变了去分化脂肪肉瘤细胞的分化状态，并在原位肿瘤中导致免疫抑制性髓系表型 | Bennett, N. E. | N/A | Gli2 Overexpression Alters the Differentiation Status of Dedifferentiated Liposarcoma Cells and Results in an Immunosuppressive Myeloid Phenotype in Orthotopic Tumors | |
| SMARCB1的丧失在上皮样肉瘤中引发可靶向的表观遗传脆弱性 | Jin, J. X. | N/A | Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in Epithelioid Sarcoma | |
| 药理学SOS1抑制剂BI-3406在体内显示出与KRAS突变肿瘤中SOS1基因敲除相当的抗肿瘤活性。 | BALTANAS, F. C. | N/A | Pharmacological SOS1 inhibitor BI-3406 demonstrates in vivo anti-tumor activity comparable to SOS1 genetic ablation in KRAS mutant tumors | |
| 独立推导预测药物诱发尖端扭转型室性心动过速的心律失常轴 | Heitmann, S. | N/A | Independent derivations of the axis of arrhythmia for predicting drug-induced torsades de pointes | |
| 增加cGMP可改善微血管运动训练的适应性，与内皮一氧化氮合酶无关。 | Winn, N. C. | N/A | Increased cGMP improves microvascular exercise training adaptations independent of endothelial nitric oxide synthase | |
| 急性簇细胞缺失导致小肠吸收不良及分泌细胞和免疫细胞谱系的改变 | Momoh, M. | N/A | Acute tuft cell ablation induces malabsorption and alterations in secretory and immune cell lineages in small intestine | |
| 隔离生长激素对寿命和代谢的直接影响 | Lasher, A. T. | N/A | Isolating the Direct Effects of Growth Hormone on Lifespan and Metabolism | |
| 数据独立采集质谱法作为元蛋白质组学的工具：使用模型微生物组进行实验室间比较 | Rajczewski, A. T. | N/A | Data-Independent Acquisition Mass Spectrometry as a Tool for Metaproteomics: Interlaboratory Comparison Using a Model Microbiome | |
| SMoRe GloS：一种高效且灵活的框架，用于推断基于代理模型参数的全局敏感性 | Bergman, D. R. | N/A | SMoRe GloS: An efficient and flexible framework for inferring global sensitivity of agent-based model parameters | |
| 基于机器学习的空间代谢谱预测揭示了形态学对星形胶质细胞能量代谢的影响 | Papavasileiou, P. | N/A | Machine Learning-based Predictions of Spatial Metabolic Profiles Demonstrate the Impact of Morphology on Astrocytic Energy Metabolism | |
| 肽-MHC靶向的逆转录病毒能够实现肿瘤特异性T细胞的体内扩增及基因传递。 | Xu, E. J. | N/A | Peptide-MHC-targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells | |
| BCR连接特异性地抑制IgE类别转换重组 | Wade-Vallance, A. K. | N/A | BCR ligation selectively inhibits IgE class switch recombination | |
| 克服突变KRAS表位翻译后修饰引起的免疫逃逸，实现TCR工程化T细胞介导的抗肿瘤活性 | Lee, J. W. | N/A | Overcoming immune evasion from post-translational modification of a mutant KRAS epitope to achieve TCR-engineered T cell-mediated antitumor activity | |
| 凝聚素介导的染色质重塑调控传统树突状细胞的分化和功能 | Adams, N. M. | N/A | Cohesin-mediated chromatin remodeling controls the differentiation and function of conventional dendritic cells | |
| 基于SATAY的化学基因组筛选揭示了抗真菌抗性机制及ATI-2307和壳聚糖敏感性的关键决定因素 | Karadzas, M. T. | N/A | SATAY-Based Chemogenomic Screening uncovers Antifungal Resistance Mechanisms and Key Determinants of ATI-2307 and Chitosan Sensitivity | |
| 沙漠生态区中暗色岩燕的适应性筑巢策略：对保护和仿生创新的启示 | Mukherjee, M. | N/A | Adaptive Nesting Strategies of Dusky Crag Martins in desert ecoregions: Implications for Conservation and Bioinspired Innovations | |
| 评估水电大坝梯度下的水禽生物多样性：了解库里楚大坝引起的河流碎片化对库里楚河流域的影响 | Nidup, T. | N/A | Assessing Aquatic Avian Biodiversity along Hydropower Dam Gradient: Understanding Impacts of Kurichhu Dam-Induced River Fragmentation in Kurrichu River Basin | |
| 亚洲狼的复杂基因组祖先及其在南方的分布，以及驱动大陆层面遗传多样性的因素 | Hennelly, L. | N/A | Complex genomic ancestry in southern regions and drivers of continental-level genetic diversity in the wolves of Asia | |
| 在杂交的Mimulus猴面花精细镶嵌体中，繁殖隔离的波动与稳定的祖先结构并存 | Farnitano, M. C. | N/A | Fluctuating reproductive isolation and stable ancestry structure in a fine-scaled mosaic of hybridizing Mimulus monkeyflowers | |
| 现代铁氧化菌支系的近期起源及其铁代谢支系忠诚度较低 | Tamre, E. | N/A | Recent origin of modern clades of iron oxidizers and low clade fidelity of iron metabolisms | |
| gReLU：一种用于DNA序列建模和设计的综合框架 | Lal, A. | N/A | gReLU: A comprehensive framework for DNA sequence modeling and design | |
| 苋菜（Amaranthus palmeri）、反枝苋（Amaranthus retroflexus）和杂交苋（Amaranthus hybridus）的染色体级别基因组组装使得进行基因组比较和鉴定性别决定区域成为可能。 | Raiyemo, D. A. | N/A | Chromosome-level assemblies of Amaranthus palmeri, Amaranthus retroflexus, and Amaranthus hybridus allow for genomic comparisons and identification of a sex-determining region | |
| MoEFold2D：结合深度学习和基于物理的专家混合，保障RNA二级结构预测 | Qiu, X. | N/A | MoEFold2D: Safeguarding RNA Secondary Structure Prediction with a Mixture of Deep Learning and Physics-based Experts | |
| 对葡萄膜黑色素瘤中INPP5A的研究揭示了新的钙瞬变现象 | Onken, M. D. | N/A | Examination of INPP5A in uveal melanoma uncovers novel calcium transients | |
| 突出力和细胞间粘附在肿瘤团簇集体迁移中起着关键作用。 | Wang, H. | N/A | Protrusion force and cell-cell adhesion play a critical role in collective tumor cluster migration | |
| 癌症中整合素蛋白社交网络的全家福光近邻分析 | Carlos, A. J. | N/A | Family-Wide Photoproximity Profiling of Integrin Protein Social Networks in Cancer | |
| 在缺乏调节性T细胞（Tregs）的情况下，IL15/IL15Rα复合物在放射治疗后能够诱导抗肿瘤免疫反应，但无法诱导祖细胞TCF1+ CD8 T细胞的扩增。 | Piper, M. | N/A | IL15/IL15Rα complex induces an anti-tumor immune response following radiation therapy only in the absence of Tregs and fails to induce expansion of progenitor TCF1+ CD8 T cells | |
| PARP7的丧失增加了I型干扰素信号传导，并通过增强免疫细胞浸润来阻止胰腺肿瘤生长。 | Kannen, V. | N/A | Loss of PARP7 increases type I interferon signalling and prevents pancreatic tumour growth by enhancing immune cell infiltration | |
| 蓝贻贝（Mytilus edulis）中首次发现六鞭毛虫（Hexamita nelsoni）：形态学、系统发育及宿主-寄生虫相互作用 | Alfjorden, A. | N/A | First report of Hexamita nelsoni in blue mussel (Mytilus edulis): morphology, phylogeny, and host-parasite interaction | |
| 不同的疟原虫蛋白激酶在雄性配子发生过程中驱动着微管组织中心、动粒和轴丝的组织结构。 | Yanase, R. | N/A | Divergent Plasmodium protein kinases drive MTOC, kinetochore and axoneme organisation in male gametogenesis | |
| 在成年心肌细胞的肌质网/内质网中蛋白质合成网络的发展 | Sandmann, C. | N/A | Development of a protein synthesis network at the sarco/endoplasmic reticulum in adult cardiac myocytes | |
| 脑-体线粒体分布模式缺乏一致性，表明存在组织特异性和个体化的调控机制 | Devine, J. | N/A | Brain-body mitochondrial distribution patterns lack coherence and point to tissue-specific and individualized regulatory mechanisms | |
| 在乳腺癌连续模型中，有丝分裂和中心体缺陷的特征 | Elowe, S. | N/A | A characterization of mitotic and centrosomal defects in a continuum model of Breast Cancer | |
| 豚草（Ambrosia artemisiifolia）在不同入侵地快速并行适应的驱动力是大型效应结构变异 | Battlay, P. | N/A | Rapid parallel adaptation in distinct invasions of Ambrosia artemisiifolia is driven by large-effect structural variants | |
| 欧洲森林和城市绿色空间中宿主-病原体群落组成的驱动因素 | Sluydts, V. | N/A | Drivers of host-pathogen community assemblies in European forests and urban green spaces | |
| 温度依赖性捕食预示着更爬行动物化的未来 | Grady, J. M. | N/A | Temperature-dependent predation predicts a more reptilian future | |
| 多代生物胁迫以ROS1依赖的方式增加了自发表观突变的发生率 | Zhang, Z. | N/A | Multi-generational biotic stress increases the rate of spontaneous epimutations in a ROS1-dependent manner | |
| 稳定性裕度计算的协调与足长、足宽、步速和体质量影响的探究 | Dussault-Picard, C. | N/A | Harmonization of Margin of Stability Calculations and Investigation of the Impact of Foot Length, Foot Width, Gait Speed, and Body Mass | |
| IgGM：一种用于功能性抗体和纳米抗体设计的生成模型 | Wang, R. | N/A | IgGM: A Generative Model for Functional Antibody and Nanobody Design | |
| 半管道（Halfpipe）：一种用于分析代谢标记RNA-seq数据以量化RNA半衰期的工具 | Mueller, J. M. | N/A | Halfpipe: a tool for analyzing metabolic labeling RNA-seq data to quantify RNA half-lives | |
| 利用生物系统中的代谢探针进行光热红外成像 | Shuster, S. O. | N/A | Optical photothermal infrared imaging using metabolic probes in biological systems | |
| 肺腺癌中Y染色体的选择性丢失通过癌/睾丸抗原调节肿瘤免疫环境 | Fischer, J. | N/A | Selective loss of Y chromosomes in lung adenocarcinoma modulates the tumor immune environment through cancer/testis antigens | |
| 造血干细胞来源的脂肪细胞消融可减轻同基因小鼠高级别浆液性癌模型中的肿瘤负担 | Woodruff, E. R. | N/A | Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma | |
| 一种辅助性NLR能够靶向细胞器膜以触发免疫反应。 | Ibrahim, T. | N/A | A helper NLR targets organellar membranes to trigger immunity | |
| 淋巴组织趋化因子检查点可防止CD8+ T细胞功能丧失 | Altenburger, L. M. | N/A | A lymphoid tissue chemokine checkpoint prevents loss of CD8+ T cell functionality | |
| 适应性免疫通过在稳态期间抑制先天淋巴细胞中的持续性IFN-γ，塑造了先天性和上皮细胞的景观。 | Mejri, O. | N/A | Adaptive immunity shapes innate and epithelial cell landscapes by silencing tonic IFN-gamma in innate lymphoid cells during homeostasis. | |
| 真菌感染的米氏琼楠花朵为三方育幼传粉系统中的甲虫传粉者提供了育幼场所。 | Liu, M.-F. | N/A | Fungus-infected Meiogyne flowers offer a brood site for beetle pollinators in a tripartite nursery pollination system | |
| 采自甜椒的桃蚜对杀虫剂的抗性 | Beekman, M. M. | N/A | Insecticide resistance in Myzus persicae collected from sweet pepper | |
| 一种新型荧光寿命层析成像技术 | Nizam, N. I. | N/A | A Novel Technique for Fluorescence Lifetime Tomography | |
| BioBrigit：一种结合深度学习和基于知识的混合方法，用于蛋白质中金属通路的建模：应用于双铜酪氨酸酶的应用 | Marechal, J.-D. | N/A | BioBrigit, A Hybrid Deep Learning and Knowledge-based Approach to Model Metal Pathways in Proteins: Application to a Di-Copper Tyrosinase | |
| HIV-1核输出复合体揭示了RNA在Crm1货物识别中的作用 | Smith, A. M. | N/A | The HIV-1 Nuclear Export Complex Reveals the Role of RNA in Crm1 Cargo Recognition | |
| 视网膜母细胞瘤蛋白（Rb）口袋结构域中与癌症相关的错义变异的结构和功能分析 | Castro, A. | N/A | Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein (Rb) pocket domain | |
| 定制基于CRISPR/Cas的表观基因组编辑器以实现可编程染色质乙酰化及降低细胞毒性 | Goell, J. H. | N/A | Tailoring a CRISPR/Cas-based Epigenome Editor for Programmable Chromatin Acylation and Decreased Cytotoxicity | |
| 尿液微生物组与糖尿病及糖尿病肾病的关系：一项系统综述 | Graells, T. | N/A | The urinary microbiome in association with diabetes and diabetic kidney disease: A systematic review | |
| 次黄嘌呤-5'-单磷酸脱氢酶（IMPDH/GuaB）抑制剂对伯氏疏螺旋体在标准及改良培养条件下生长的影响 | Siegel, E. L. | N/A | Effects of Inosine-5'-Monophosphate Dehydrogenase (IMPDH/GuaB) Inhibitors on Borrelia burgdorferi Growth in Standard and Modified Culture Conditions | |
| 常见调控突变提高了铜绿假单胞菌在抗生素暴露下的单细胞存活率。 | Ritz, D. | N/A | Common regulatory mutation increases single-cell survival to antibiotic exposures in Pseudomonas aeruginosa. | |
| 关闭差距：测试碳青霉烯和头孢菌素在治疗晚期炭疽中的疗效 | Sittner, A. | N/A | Closing the gaps: testing the efficacy of carbapenem and cephalosporins in treating late-stage anthrax | |
| 评估氧扰动和过度曝气对活性污泥系统中可溶性微生物产物（SMP）生成和释放的影响 | Zhou, X. | N/A | Assessing Oxygen Perturbation and Over-Aeration Impacts on Soluble Microbial Products (SMP) Production and Release in Activated Sludge Systems | |
| 禽类和牛场作为产ESBL大肠杆菌储库的一体化健康评估 | Malik, H. | N/A | One Health assessment of poultry and cattle farms as reservoirs for ESBL-producing Escherichia coli | |
| 探究氧气扰动下潜在的微生物对代谢物产量增强的贡献：一种整合的宏基因组学和代谢组学方法 | Zhou, X. | N/A | Investigating Potential Microbial Contributors to Enhanced Metabolite Production under Oxygen Perturbations: An Integrated Metagenomic and Metabolomic Approach | |
| 截留末端未脱磷酸的十一碳酰磷酸连接的寡糖中间体 | Hong, Y. | N/A | Sequestration of dead-end undecaprenyl phosphate-linked oligosaccharide intermediate | |
| 通过引导微生物代谢生产高附加值生物化学品，实现废水资源回收 | Zhou, X. | N/A | Resource Recovery from Wastewater By Directing Microbial Metabolism Toward Production of Value-added Biochemicals | |
| 早期生命牛奶饮食塑造婴儿肠道微生物群：关于微生物对母乳和配方奶的适应性证据。 | Lawson, M. A. E. | N/A | Early life milk diets shape infant gut microbiota: evidence of microbial plasticity in response to breast and formula milk. | |
| 水杨酸衍生物的抗结核潜力及其pH驱动的抗菌机制 | Laudouze, J. | N/A | Anti-tubercular potential and pH-driven mode of action of salicylic acid derivatives | |
| 燕麦（Avena sativa L.）对干旱胁迫的蛋白质组响应 | Chen, C. | N/A | Proteomic responses of oat (Avena sativa L.) to drought stress | |
| TDRD3作为一种选择性自噬受体，在自噬过程中具有双重功能，既参与自噬作用，又调节应激颗粒的稳定性。 | Lloyd, R. E. | N/A | TDRD3 functions as a selective autophagy receptor with dual roles in autophagy and modulation of stress granule stability | |
| 寄生传播时间选择塑造了宿主冈比亚按蚊的转录反应，并提示免疫逃避 | Silva, L. M. | N/A | Selection on time to parasite transmission shapes the host Anopheles gambiae transcriptional response and suggests immune evasion | |
| 评估辐射敏感性指数及12种趋化因子基因表达特征在CLIA实验室中的临床应用 | Berglund, A. | N/A | Evaluating the Radiation Sensitivity Index and 12-chemokine gene expression signature for clinical use in a CLIA laboratory | |
| scooby: 在单细胞分辨率下从DNA序列建模多模态基因组特征 | Gagneur, J. | N/A | scooby: Modeling multi-modal genomic profiles from DNA sequence at single-cell resolution | |
| 嵌合去泛素化酶工程揭示了USP30特异性抑制的结构基础及DUB配体结合的框架 | Kazi, N. H. | N/A | Chimeric deubiquitinase engineering reveals structural basis for specific inhibition of USP30 and a framework for DUB ligandability | |
| 鉴定孤儿GPR25为趋化因子CXCL17的受体 | Hu, W.-F. | N/A | Identification of the orphan GPR25 as a receptor of the chemokine CXCL17 | |
| 通过贝叶斯模型选择整合蛋白质-多肽复合物的建模，使用AlphaFold和NMR化学位移扰动数据 | Benavides, T. L. | N/A | Integrative Modeling of Protein-Polypeptide Complexes by Bayesian Model Selection using AlphaFold and NMR Chemical Shift Perturbation Data | |
| 气道应用的IVT mRNA疫苗需要特定的序列设计和高标准的纯化，以去除具有破坏性的双链RNA污染物。 | Zhang, J. | N/A | Airway applied IVT mRNA vaccine needs specific sequence design and high standard purification that removes devastating dsRNA contaminant | |
| 利用光遗传学技术快速可逆地调控出芽酵母细胞周期进程 | Koutsoumpa, A. | N/A | Rapid and reversible regulation of cell cycle progression in budding yeast using optogenetics | |
| 病毒RNA kaposin促进的核体重组促进了卡波西肉瘤相关疱疹病毒基因表达 | Kleer, M. | N/A | Nuclear body reorganization by the viral RNA kaposin promotes Kaposi's sarcoma-associated herpesvirus gene expression | |
| 评估非洲豆蔻（Aframomum melegueta）和几内亚胡椒（Piper guineense）提取物对黄瓜果实腐烂病原菌的抗菌活性 | Akpan, P. S. | N/A | Assessing the antimicrobial activity of Aframomum melegueta and Piper guineense extract on pathogens of rot diseases of cucumber fruit | |
| BRCA2 C端夹结构重构RAD51二聚体以结合B型DNA，从而维持复制叉的稳定性 | Longo, M. A. | N/A | BRCA2 C-terminal clamp restructures RAD51 dimers to bind B-DNA for replication fork stability | |
| 一个新颖的OsIAA3-OsARF16-OsBUL1模块调控水稻的粒型 | Xian, F. | N/A | A novel OsIAA3-OsARF16-OsBUL1 module regulates grain size in rice | |
| 基因组大小与非转录区域大小之间的线性相关性 | Chen, Z.-R. | N/A | The linear correlation between genome size and the size of the non-transcribing region | |
| BTFBS：基于深度学习的细菌转录因子与结合位点预测 | Jin, B. | N/A | BTFBS: binding-prediction of bacterial transcription factors and binding sites based on deep learning | |
| # BioRxiv 2024-09-21 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 无监督机器学习揭示了HeLa细胞在细胞周期阻滞解除后基因表达的时间成分 | Maimon, T. | N/A | Unsupervised machine learning reveals temporal components of gene expression in HeLa cells following release from cell cycle arrest | |
| SARS-CoV-2和HSV-1诱导人脑脊液中淀粉样蛋白聚集，导致可溶性蛋白质急剧减少。 | Christ, W. | N/A | SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion | |
| 冷适应性鲑科鱼类在世代内和跨世代环境变暖中的转录组响应 | Penney, C. M. | N/A | Transcriptomic responses to within- and transgenerational environmental warming in a cold-adapted salmonid | |
| 通过交叉拟合加速基于R2的高维中介效应区间估计 | Xu, Z. | N/A | Speeding up interval estimation for R2-based mediation effect of high-dimensional mediators via cross-fitting | |
| 活体中皮层下磁性物质的非指数横向弛豫衰减特性 | Oliveira, R. | N/A | In-vivo characterization of magnetic inclusions in the subcortex from non-exponential transverse relaxation decay | |
| 肌动蛋白介导的细胞核形变调控多纤毛室管膜细胞的分化。 | Basso, M. | N/A | Actin-based deformations of the nucleus control multiciliated ependymal cell differentiation. | |
| mbctools：一个用户友好的宏条形码分析和跨平台管道，用于分析多种生物的大量多样性扩增子测序数据。 | Barnabe, C. | N/A | mbctools: A User-Friendly Metabarcoding and Cross-Platform Pipeline for Analyzing Multiple Amplicon Sequencing Data across a Large Diversity of Organisms | |
| 超低场儿科MRI在低收入和中等收入国家：使用多方向U-Net的超分辨率技术 | Baljer, L. | N/A | Ultra-low-field paediatric MRI in low- and middle-income countries: super-resolution using a multi-orientation U-Net | |
| 丁香酚通过NRF2介导的氧化应激途径对1型糖尿病的保护作用 | Jiang, Y. | N/A | The protective roles of Eugenol on type 1 diabetes mellitus through NRF2 mediated oxidative stress pathway | |
| 基于免疫受体分析和多克隆应答细胞的单细胞RNA表达的TCR转基因克隆筛选 | Debeuf, N. | N/A | TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders | |
| 星形胶质细胞在海马体-内嗅皮层突触中介导两种形式的峰时依赖性抑制。 | Martinez-Gallego, I. | N/A | Astrocytes mediate two forms of spike timing-dependent depression at entorhinal cortex-hippocampal synapses | |
| 胎盘纳米颗粒介导的IGF1基因治疗在豚鼠模型中纠正了胎儿生长受限 | Davenport, B. | N/A | Placental Nanoparticle-mediated IGF1 Gene Therapy Corrects Fetal Growth Restriction in a Guinea Pig Model | |
| 目标学习而非反向传播解释了哺乳动物新皮层中的学习过程 | Aceituno, P. V. | N/A | Target Learning rather than Backpropagation Explains Learning in the Mammalian Neocortex | |
| 氨基酸与葡萄糖发酵维持小鼠及人类恶性胶质瘤细胞的ATP含量 | Lee, D. C. | N/A | Amino Acid and Glucose Fermentation Maintain ATP Content in Mouse and Human Malignant Glioma Cells | |
| 用于研究疟原虫主要毒力因子功能的一个系统 | Cronshagen, J. | N/A | A system for functional studies of the major virulence factor of malaria parasites | |
| 线粒体输入蛋白TIMM50缺乏的生化和神经生理学效应 | Paz, E. | N/A | Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50 | |
| 珊瑚宿主积极积累无机碳以维持与共生藻的共生关系 | Zhang, B. | N/A | Coral hosts actively accumulate inorganic carbon for Symbiodiniaceae to maintain symbiotic relationships | |
| 丘脑皮层对分层认知控制的贡献 | Chen, X. | N/A | Thalamocortical contributions to hierarchical cognitive control | |
| β-1,6-葡聚糖在双层真菌细胞壁的结构和重塑中起着核心作用。 | Bekirian, C. | N/A | Beta-1,6-glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall | |
| 植物系统中的Mobius组装强调了基因调控中的启动子-编码序列-终止子相互作用 | Kocaoglan, E. G. | N/A | Mobius Assembly for Plant Systems highlights promoter-coding sequence terminator interaction in gene regulation | |
| 参考基因组的纬度梯度 | Linck, E. B. | N/A | A latitudinal gradient of reference genomes | |
| 通过折叠和稳定性的全面指南，揭示细胞色素c与疾病的关联 | Yousaf, M. A. | N/A | A comprehensive guide through the fold and stability of cytochrome c with implications for disease | |
| 下颌关节假体在完整咀嚼周期中的生物力学评估 | Ghosh, R. | N/A | Biomechanical Evaluation of Temporomandibular Joint Implants Under Complete Mastication Cycle | |
| 单倍型解析组装提供了对新疆最古老葡萄品种（木纳格）基因组组成的深入了解。 | Zhong, H. | N/A | Haplotype-resolved assemblies provide insights into genomic makeup of the oldest grapevine cultivar (Munage) in Xinjiang | |
| 基于深度学习的基因扰动效应预测尚未超越简单的线性方法。 | Ahlmann-Eltze, C. | N/A | Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods | |
| 将全长FLT1表达重定向至其可溶性异构体可促进缺血后血管生成。 | Bundalo, M. | N/A | Redirecting full-length FLT1 expression towards its soluble isoform promotes postischemic angiogenesis | |
| 定性脑电图异常表明大脑网络向抑制主导型转变。来自EU-AIMS LEAP研究的结果显示 | Juarez-Martinez, E. L. | N/A | Qualitative EEG abnormalities signal a shift towards inhibition-dominated brain networks. Results from the EU-AIMS LEAP studies | |
| 通过个性化抗原无关筛选方法识别的T细胞受体靶向共享的新抗原KRAS Q61H | Lennerz, V. | N/A | T-cell receptors identified by a personalized antigen-agnostic screening approach target shared neoantigen KRAS Q61H | |
| TBC1D24调控线粒体与内质网-线粒体接触位点 | Benhammouda, S. | N/A | TBC1D24 regulates mitochondria and endoplasmic reticulum-mitochondria contact sites | |
| 在妊娠中期，母体血浆中apelin水平较低与重度、早发型胎儿生长受限的不良妊娠结局相关。 | Braun, N. | N/A | Low maternal plasma apelin in the second trimester is associated with adverse pregnancy outcome in severe, early-onset fetal growth restriction | |
| 通过ERECTA的触发开关机制预防配体感知前后的不当信号传递 | Chen, L. | N/A | Preventing Inappropriate Signals Pre- and Post-Ligand Perception by a Toggle-Switch Mechanism of ERECTA | |
| 主要镰刀菌物种在温度和水活性约束组合下的生理生态行为 | Foulongne-Oriol, M. | N/A | Ecophysiological Behaviour Of Major Fusarium Species In Response To Combinations Of Temperature And Water Activity Constraints | |
| Sox9可防止视网膜退化，并在成年小鼠眼中对角膜缘干细胞的分化起着必要作用。 | Hurtado, A. | N/A | Sox9 prevents retinal degeneration and is required for limbal stem cell differentiation in the adult mouse eye | |
| 亲缘关系密切的叶蝉亚科中微生物群落的显著差异：Typhlocybinae和Eurymelinae（叶蝉科，半翅目） | Kobiałka, M. | N/A | Extremely distinct microbial communities in closely related leafhopper subfamilies: Typhlocybinae and Eurymelinae (Cicadellidae, Hemiptera) | |
| HuR对稳态B细胞信号转录后调控对于先天性B细胞的维持和功能是必需的。 | Capitan-Sobrino, D. | N/A | Post-transcriptional control of homeostatic B- cell signalling by HuR is required for innate B cell maintenance and function. | |
| TIRTL-seq：深度、定量且经济实惠的配对TCR受体组测序 | Pogorelyy, M. V. | N/A | TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing | |
| 物种间生长特征的差异正在推动谷物-豆类间作产量：基于聚合数据集的统计学习方法 | Mahmoud, R. | N/A | Differences in growth features between species are driving cereal-legume intercrop yield: a statistical learning approach based on aggregated dataset | |
| BirdNET在欧洲城市声学鸟类监测方面与专家一样出色。 | Fairbairn, A. J. | N/A | BirdNET is as good as experts for acoustic bird monitoring in a European city | |
| 蒸气压亏缺主导了生态系统光合量子产量的时空变化。 | Yu, L. | N/A | Vapor pressure deficit dominates the spatiotemporal variations in ecosystem photosynthetic quantum yield | |
| 伊利诺伊州西尼罗病毒传播媒介（库蚊和淡色库蚊）中广泛存在的杀虫剂抗性机制证据 | Noel, K. | N/A | Mechanistic evidence of widespread insecticide resistance among Illinois West Nile virus vectors (Culex pipiens and Culex restuans) | |
| 灵长类动物（包括人类）大脑进化与手部灵巧性的协同演化 | Baker, J. | N/A | The coevolution of encephalization and manual dexterity in hominins and other primates | |
| 纤毛虫细胞衰老的起源 | Mitteldorf, J. | N/A | Origin of Cellular Senescence in Ciliates | |
| 基因组和表型预测在苹果育种中应用的评估 | Jung, M. | N/A | Evaluation of genomic and phenomic prediction for application in apple breeding | |
| 通过解决合成环状RNA中的污染物来缓解细胞功能障碍 | Zhang, Z. | N/A | Mitigating Cellular Dysfunction by Addressing Contaminants in Synthetic circRNA | |
| 胶质母细胞瘤对溶瘤HSV1反应的纵向分析指导PLX3397联合用药以增强病毒易感性 | Ito, H. | N/A | Longitudinal analysis of glioblastoma response to oncolytic HSV1 guides PLX3397 combination for enhanced viral permissiveness | |
| MAASWERP研究：一项关于测量老年小鼠主动脉生物力学的国际比较案例研究 | Neutel, C. H. G. | N/A | The MAASWERP study: An international, comparative case study on measuring biomechanics of the aged murine aorta | |
| 跨表达分析揭示了空间转录组学中协调基因表达的模式 | Sarwar, A. | N/A | Cross-expression analysis reveals patterns of coordinated gene expression in spatial transcriptomics | |
| 通过使用扭曲分子的属性条件训练来提高3D分子生成的结构合理性 | Vost, L. | N/A | Improving Structural Plausibility in 3D Molecule Generation via Property-Conditioned Training with Distorted Molecules | |
| 利用MELISSA模型进行安全评估的整合位点数据建模 | Lin, T.-Y. | N/A | Modeling integration site data for safety assessment with MELISSA | |
| BrainSTEM：一种多分辨率胎儿脑图谱，用于评估人中脑培养的保真度 | Toh, H. | N/A | BrainSTEM: A multi-resolution fetal brain atlas to assess the fidelity of human midbrain cultures | |
| 校准额外的计算工具扩展了ClinGen在PP3/BP4标准下对变异分类的推荐选项 | Bergquist, T. | N/A | Calibration of additional computational tools expands ClinGen recommendation options for variant classification with PP3/BP4 criteria | |
| 整合多种实验信息以辅助GRASP进行蛋白质复合物结构预测 | Xie, Y. | N/A | Integrating various Experimental Information to Assist Protein Complex Structure Prediction by GRASP | |
| 从多种RNA-DNA连接数据中检测统计学上稳健的相互作用 | Zehr, S. | N/A | Detection of statistically robust interactions from diverse RNA-DNA ligation data | |
| Bolero：一种专门的工作流程，用于从结合5RACE扩增转录本的长读长测序方法中解析乙型肝炎病毒转录组 | Grand, X. | N/A | Bolero: a dedicated workflow to decipher Hepatitis B virus transcriptome from long-reads sequencing method coupled to 5RACE amplification of transcripts | |
| 从DNA序列预测和功能解析染色体间基因组架构的TwinC方法 | Jha, A. | N/A | Prediction and functional interpretation of inter-chromosomal genome architecture from DNA sequence with TwinC | |
| 肌纤维特异性FoxP1敲除可保护雄性小鼠免受胰腺癌引起的肌肉萎缩，但对雌性小鼠无效。 | Schonk, M. M. | N/A | Myofiber-specific FoxP1 knockout protects against pancreatic cancer-induced muscle wasting in male but not female mice. | |
| 成纤维细胞调节人乳头瘤病毒阳性角质形成细胞的转化潜能 | James, C. D. | N/A | Fibroblasts Regulate the Transformation Potential of Human Papillomavirus-positive Keratinocytes | |
| 视网膜神经节细胞对阿尔茨海默病中致病性tau的易感性 | Davis, M. R. | N/A | Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease | |
| 一种动力学筛选方法加速了靶向蛋白质降解剂的开发 | Fan, A. T. | N/A | A Kinetic Scout Approach Accelerates Targeted Protein Degrader Development | |
| 选择性Rho激酶2抑制剂KD025在精神分裂症的遗传和药理学小鼠模型中表现出类似抗精神病药物的效果。 | Tanaka, R. | N/A | Antipsychotic-like effects of the selective Rho-kinase 2 inhibitor KD025 in genetic and pharmacological mouse models of schizophrenia | |
| 不活动介导的分子适应：从一种新的临床前体力活动减少模型中获得的见解 | Meyer, A. | N/A | Inactivity-mediated molecular adaptations: insights from a novel pre-clinical model of physical activity reduction | |
| 体外补充DHA可抑制人原代巨噬细胞中前列腺素E2的形成 | Kirchhoff, R. | N/A | Ex vivo DHA supplementation suppresses prostaglandin E2 formation in primary human macrophages | |
| 银屑病血液和皮肤中免疫细胞的单细胞图谱 | Deng, J. | N/A | Single-cell Landscape of Immune Cells in Blood and Skin in Psoriasis | |
| 听音乐在双眼竞争期间调节对绘画的视觉感知 | Jiang, X. | N/A | Listening to music modulates visual perception of paintings during binocular rivalry | |
| 跨功能模块的生物衰老高维表征 | Ying, K. | N/A | High-dimensional Ageome Representations of Biological Aging across Functional Modules | |
| 定量蛋白质组学揭示了M1和M2单核细胞来源的人类巨噬细胞外泌体货物的差异 | Pantazi, P. | N/A | Quantitative proteomics reveals differential extracellular vesicle cargo from M1 and M2 monocyte-derived human macrophages | |
| 谷氨酰胺的可用性调节组织中树突状细胞亚群 | Lobel, G. P. | N/A | Glutamine availability regulates cDC subsets in tissue | |
| CCR2限制了CD8 TRM细胞的炎症功能，这些功能在从WNV脑炎恢复期间损害了识别记忆 | Ai, S. | N/A | CCR2 limits inflammatory functions of CD8 TRM cells that impair recognition memory during recovery from WNV encephalitis | |
| 通过性状-环境关系揭示的环境适应微生物策略 | Ren, M. | N/A | Microbial strategies of environmental adaptation revealed by trait-environmental relationships | |
| 基于生理学的人口模型/非洲十三个入侵物种的GIS分析：为何生物学至关重要 | Gutierrez, A. P. | N/A | Physiologically based demographic model/GIS analyses of thirteen invasive species in Africa: why the biology matters | |
| 纠缠进化模型：应用于自适应突变 | Ross, P. | N/A | Entangled Evolution Model: Application to Adaptive Mutation | |
| 水蓼（Amaranthus tuberculatus）中性的进化、多样性和遗传结构 | Kreiner, J. M. | N/A | The evolution, diversity, and genetic architecture of sex in waterhemp (Amaranthus tuberculatus) | |
| 个体间不同的重组景观是由多态的可移动元件驱动的。 | Huang, Y. | N/A | Varying recombination landscapes between individuals are driven by polymorphic transposable elements | |
| 小鼠造血系统的克隆动态与体细胞演化 | Kapadia, C. D. | N/A | Clonal dynamics and somatic evolution of haematopoiesis in mouse | |
| 禾谷镰刀菌假基因的鉴定与结构表征。 | Rau, D. | N/A | Identification and structural characterization of pseudogenes in Fusarium graminearum. | |
| 利用多层单细胞组学技术表征人巨细胞病毒特异性CD8+ T细胞 | Gemuend, I. | N/A | Characterizing human CMV-specific CD8+ T cells using multi-layer single-cell omics | |
| 具有触发阀的开敞式水渠系统中毛细流动的动力学特性 | Tokihiro, J. C. | N/A | The dynamics of capillary flow in an open-channel system featuring trigger valves | |
| 一个新的用于估计同义替换选择作用的比较框架。 | Verdonk, H. | N/A | A new comparative framework for estimating selection on synonymous substitutions. | |
| 超越关联性：疾病致病基因因果关系抽取基准数据集（CRED）、其比较评估、解读与应用 | Bansal, N. | N/A | Beyond associations: A benchmark Causal Relation Extraction Dataset (CRED) of disease-causing genes, its comparative evaluation, interpretation and application | |
| 早期肺癌肿瘤微环境中存在的Tenascin-C通过整合素激活和FAK促进肿瘤进展。 | Mendoza, M. C. | N/A | Tenascin-C in the early lung cancer tumor microenvironment promotes progression through integrin activation and FAK | |
| 大麻二酚（CBD）对人胶质母细胞瘤细胞核心区和浸润边界区的差异性抗增殖作用 | Abassi-Rana, G. | N/A | DIFFERENTIAL ANTIPROLIFERATIVE EFFECTS OF CANNABIDIOL (CBD) IN THE CORE AND INFILTRATIVE BOUNDARY OF HUMAN GLIOBLASTOMA CELLS | |
| CDK4失活平衡了三阴性乳腺癌细胞对凋亡的抵抗与代谢敏感性的增强 | Ziegler, D. V. | N/A | CDK4 inactivation balances resistance to apoptosis with heightened metabolic sensitivity in triple negative breast cancer cells | |
| 截短的补体因子H Y402基因疗法治愈C3肾小球肾炎 | Chew, L. A. | N/A | Truncated Complement Factor H Y402 Gene Therapy Cures C3 Glomerulonephritis | |
| 室温气溶胶脱水绿色荧光蛋白 | Pan, Z. | N/A | Room Temperature Aerosol Dehydration of Green Fluorescence Protein | |
| 代谢组学和转录组学分析的整合揭示了ChREBP转录因子在能量代谢中的新调控功能 | An, J. | N/A | Integration of metabolomic and transcriptomic analyses reveals novel regulatory functions of the ChREBP transcription factor in energy metabolism | |
| GCK-MODY中独特的持续时间与饮食依赖性脂质谱及肾脏并发症 | Huang, Y. | N/A | Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY | |
| 牛淋巴和非淋巴组织中的树突状细胞亚群：正在进行的工作 | Talker, S. C. | N/A | Bovine dendritic-cell subsets in lymphoid and non-lymphoid tissues: work in progress | |
| 一种人类同源的SIR2抗病毒蛋白通过TLR途径介导免疫 | Bonhomme, D. | N/A | A human homolog of SIR2 antiphage proteins mediates immunity via the TLR pathway | |
| 一种用于重建性社会学习演化的神经网络模型 | Chisausky, J. | N/A | A neural network model for the evolution of reconstructive social learning | |
| 优化冷冻保存遗传资源在动物种群选择和保护中的应用 | Jacques, A. | N/A | Optimizing the use of cryopreserved genetic resources for the selection and conservation of animal populations | |
| 使用自回归生成模型重建祖先蛋白质序列 | De Leonardis, M. | N/A | Reconstruction of ancestral protein sequences using autoregressive generative models | |
| 推进对抗胶质母细胞瘤的临床反应：评估SHP1705 CRY2激活剂在临床前模型中的疗效及在I期试验中的安全性 | Chan, P. | N/A | Advancing Clinical Response Against Glioblastoma: Evaluating SHP1705 CRY2 Activator Efficacy in Preclinical Models and Safety in Phase I Trials | |
| 苯甲酸钠通过SKN-1/Nrf2信号通路促进脂肪积累和衰老：来自秀丽隐杆线虫模型的证据 | Lee, J. D. | N/A | Sodium Benzoate Promotes Fat Accumulation and Aging via the SKN-1/Nrf2 Signaling Pathway: Evidence from the Caenorhabditis elegans Model | |
| 比较多系统萎缩与帕金森病中的α-突触核蛋白相互作用组，揭示了独特的和共有的病理特征。 | Killinger, B. A. | N/A | Comparing alpha-synuclein-interactomes between multiple systems atrophy and Parkinsons disease reveals unique and shared pathological features. | |
| 用于从多通道音频中定位啮齿动物发声的Vocal Call Locator基准（VCL） | Peterson, R. E. | N/A | Vocal Call Locator Benchmark (VCL) for localizing rodent vocalizations from multi-channel audio | |
| 来自精神分裂症个体的hiPSC衍生星形胶质细胞促进类似小胶质细胞的吞噬作用和趋化性改变 | Cardozo, P. L. | N/A | hiPSC-derived astrocytes from individuals with schizophrenia promote alterations in phagocytosis and chemotaxis of microglial-like cells | |
| 下肢指向评估不完全脊髓损伤后节段间动力学及其与本体感觉障碍的关联作用。 | Malik, R. N. | N/A | Lower limb pointing to assess intersegmental dynamics after incomplete spinal cord injury and the associated role of proprioceptive impairments. | |
| 在青蛙变态发育过程中，脊髓神经元的多样性随着从游泳到四肢运动的转变呈指数级增长。 | Vijatovic, D. | N/A | Spinal neuron diversity scales exponentially with swim-to-limb transformation during frog metamorphosis | |
| 在情绪面孔匹配任务中并发的大规模脑动态及其与行为和心理健康的关系 | Korponay, C. | N/A | Concurrent large-scale brain dynamics during the emotional face matching task and their relation to behavior and mental health | |
| 人类内侧丘脑枕核参与面部和触觉处理，并根据当前的刺激动态调整其皮质连接性。 | Gaudet, M. | N/A | Human medial pulvinar is involved in face and tactile processing and dynamically adjusts its cortical connectivity based on ongoing stimulation | |
| 在声学听力听者和耳蜗植入使用者中，高呈现声级下听觉努力增加和言语辨别能力下降 | Huang, C. G. | N/A | Increased listening effort and decreased speech discrimination at high presentation sound levels in acoustic hearing listeners and cochlear implant users | |
| 脂联素在母体肥胖暴露的成年后代中，恢复了阻力血管的胆碱能舒张作用。 | Murphy, M. | N/A | Adiponectin restores cholinergic vasodilation in resistance vessels from adult offspring exposed to maternal obesity in utero | |
| 终身健身优势：繁殖地忠诚度和近亲繁殖成本低，使得一种鸟类合作繁殖者能够容忍近亲繁殖。 | Shah, S. | N/A | Lifetime fitness benefits of breeding site fidelity and low costs of inbreeding permit inbreeding tolerance in an avian cooperative breeder | |
| 纹状体和海马中奖励的情感和信息成分的差异表征 | Shen, X. | N/A | Differential representations for affective and informative components of reward in the striatum and hippocampus | |
| 前扣带回前额叶皮层中的组蛋白去乙酰化酶5限制与情境相关的可卡因寻求行为 | Barry, S. M. | N/A | Histone deacetylase 5 in prelimbic prefrontal cortex limits context-associated cocaine seeking | |
| 乙酰胆碱在不确定性下的强化学习和决策中的作用 | Kurtenbach, H. | N/A | A role for acetylcholine in reinforcement learning and decision making under uncertainty | |
| 一项大规模队列研究（n = 591）探讨了丘脑间粘连的存在与否对认知、神经影像学和遗传结果的影响。 | Vidal, J. P. | N/A | A large cohort study (n = 591) on the impact of the presence or absence of the interthalamic adhesion: cognitive, neuroimaging, and genetic results | |
| 可卡因自我戒断促进了小胶质细胞对星形胶质细胞的修剪，从而推动了可卡因的觅药行为。 | Testen, A. | N/A | Abstinence from cocaine self-administration promotes microglia pruning of astrocytes which drives cocaine-seeking behavior | |
| 刺激椭圆囊不规则纤维会在前庭核复合体（VNC）中产生从前到后的活动梯度，但不会在前庭小脑（VeCb）中产生。 | Holt, A. G. | N/A | Stimulation of otolith irregular fibers produces a rostro-caudal gradient in activity in the vestibular nuclear complex (VNC), but not the vestibulocerebellum (VeCb) | |
| SETα和SETβ在早期细胞命运决定中具有不同的作用 | Lim, P. S. L. | N/A | Distinct Roles for SETα and SETβ in Early Cell Fate Decisions | |
| 传粉者Eristalis tenax中固有花卉偏好的消失 | Mishra, A. | N/A | Extinction of innate floral preferences in the pollinator Eristalis tenax | |
| 椎间盘髓核细胞网络建模 | Tseranidou, S. | N/A | Nucleus Pulposus Cell Network Modelling in the Intervertebral Disc | |
| 统一大模型：一种全新整体建模范式，用于在完整和谐的尺度上研究生物系统 | Aucello, R. | N/A | UnifiedGreatMod: A New Holistic Modeling Paradigm for Studying Biological Systems on a Complete and Harmonious Scale | |
| 单细胞网络方法解析妇科及乳腺癌中的代谢调控 | Srivastava, A. | N/A | A Single-Cell Network Approach to Decode Metabolic Regulation in Gynecologic and Breast Cancers | |
| 小胶质细胞决定免疫挑战环境，并促进布洛芬在人视网膜类器官中的作用。 | Schmied, V. | N/A | Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids. | |
| 疱疹病毒膜融合激活的变构机制 | Gonzalez-Del Pino, G. L. | N/A | Allosteric mechanism of membrane fusion activation in a herpesvirus | |
| 通过Sideroxydans lithotrophicus ES-1中的MtoAB孔蛋白-多血红素细胞色素复合物进行的微生物磁铁矿氧化 | Keffer, J. L. | N/A | Microbial magnetite oxidation via MtoAB porin-multiheme cytochrome complex in Sideroxydans lithotrophicus ES-1 | |
| 大肠杆菌中rRNA操纵子的聚集被σH破坏。 | Ho, K. | N/A | Clustering of rRNA operons in E. coli is disrupted by σH | |
| 生牛奶中甲型H5N1流感病毒的热灭活谱 | Nooruzzaman, M. | N/A | Thermal inactivation spectrum of influenza A H5N1 virus in raw milk | |
| 巨型转座子推动了热厌氧杆菌（Thermoanaerobacter kivui）对一氧化碳的适应 | Hocq, R. | N/A | A megatransposon drives the adaptation of Thermoanaerobacter kivui to carbon monoxide | |
| 在受限条件下细菌的生长需要转录适应以抵抗代谢物引起的膨压增加 | Le Blanc, L. | N/A | Bacterial growth under confinement requires transcriptional adaptation to resist metabolite-induced turgor pressure build-up | |
| 一种隐秘的噬菌体转录因子通过宿主基因调控驱动表型变化 | Lally, P. | N/A | A Cryptic Prophage Transcription Factor Drives Phenotypic Changes via Host Gene Regulation | |
| 饮食诱导的Rad51c突变小鼠线粒体DNA复制不稳定性驱动炎症性贫血的性别偏向 | Tomaszowski, K.-H. | N/A | Diet induced mitochondrial DNA replication instability in Rad51c mutant mice drives sex-bias in anemia of inflammation | |
| 神经化样蛋白差异性激活Notch配体 | Airich, A. | N/A | Neuralized-like proteins differentially activate Notch ligands | |
| 一个依赖于气候和人口的扩散模型预测了白纹伊蚊在欧洲的传播情况。 | Barman, S. | N/A | A climate and population dependent diffusion model forecasts the spread of Aedes Albopictus mosquitoes in Europe | |
| 使用SomaScan和Olink检测方法进行蛋白质丰度定量时，体外溶血和反复冻融循环的影响 | Candia, J. | N/A | Effects of in vitro hemolysis and repeated freeze-thaw cycles in protein abundance quantification using the SomaScan and Olink assays | |
| 藻胆蛋白使海洋硅藻表现出社会行为 | Font-Munoz, J. S. | N/A | Phytochromes Enable Social Behavior in Marine Diatoms | |
| 保守非编码元件的剧烈进化变化伴随着Caenorhabditis inopinata的非凡特征 | Tamagawa, K. | N/A | Dramatic evolutionary changes of conserved noncoding elements accompanied by extraordinary features of Caenorhabditis inopinata | |
| 揭示氨基糖苷类药物与假尿苷在IRES翻译中的分子相互作用 | Zhao, Y. | N/A | Unveil the Molecular Interplay between Aminoglycosides and Pseudouridine in IRES Translation | |
| ERAP1活性不仅调节免疫肽组，还影响癌细胞的蛋白质组、代谢和应激反应。 | Nikopaschou, M. | N/A | ERAP1 activity modulates the immunopeptidome but also affects the proteome, metabolism and stress responses in cancer cells | |
| 特定C2H2锌指结构域中的构象动力学使锌响应基因抑制在S. pombe中得以实现 | Wadhwa, V. | N/A | Conformational dynamics in specialized C2H2 zinc finger domains enable zinc-responsive gene repression in S. pombe | |
| Rubisco包装及天然β-羧酶体的化学计量组成 | Sun, Y. | N/A | Rubisco packaging and stoichiometric composition of a native β-carboxysome | |
| 从头设计的别构可调蛋白纤维的成核限制组装和极性生长 | Shen, H. | N/A | Nucleation limited assembly and polarized growth of a de novo-designed allosterically modulatable protein filament | |
| AlphaFold2和AlphaFold3在人类与寄生虫相互作用预测中导致显著不同的结果 | Ozden, B. | N/A | AlphaFold2 and AlphaFold3 leads to significantly different results in human-parasite interaction prediction | |
| 基因组中的基序分布提供了关于基因簇集和协同调控的见解。 | Chakraborty, A. | N/A | Motif distribution in genomes gives insights into gene clustering and co-regulation | |
| BioPAX-Explorer：一个面向对象的Python框架，用于克服查询生物网络的复杂性 | Moreews, F. | N/A | BioPAX-Explorer: a Python Object-Oriented framework for overcoming the complexity of querying biological networks | |
| 一种环状多肽通过结合异常暴露的SNAP25靶向胶质母细胞瘤 | Arias, A. G. | N/A | A CYCLIC PEPTIDE TARGETS GLIOBLASTOMA BY BINDING TO ABERRANTLY EXPOSED SNAP25 | |
| 利什曼原虫墨西哥亚种中N-乙酰转移酶10（NAT10）的功能表征 | Rodrigues Maran, S. | N/A | Functional characterization of N-acetyltransferase 10 (NAT10) in Leishmania mexicana | |
| 水生哺乳动物中普遍存在的选择放松 | Farina, B. M. | N/A | Widespread selection relaxation in aquatic mammals | |
| 胚胎干细胞中TF-DNA识别的双峰特异性 | Povolotskii, M. | N/A | Bimodal Specificity of TF-DNA Recognition in Embryonic Stem Cells | |
| 通过嵌合eCLIP方法在RNA结合蛋白依赖的方式下映射snoRNA与目标RNA的相互作用 | Song, Z. | N/A | Mapping snoRNA-target RNA interactions in an RNA binding protein-dependent manner with chimeric eCLIP | |
| # BioRxiv 2024-09-20 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| PPARγ域间通讯的结构基础 | Mosure, S. A. | N/A | Structural basis of interdomain communication in PPARγ | |
| 灵长类前额叶皮层中对扫视运动的预期性和回顾性表征 | Calangiu, I. | N/A | Prospective and retrospective representations of saccadic movements in primate prefrontal cortex | |
| 用于分析和估计随机生化反应网络的滤波有限状态投影方法。 | D'Ambrosio, E. S. | N/A | Filtered finite state projection method for the analysis and estimation of stochastic biochemical reaction networks. | |
| 膜嵌入的人类T细胞受体-CD3复合物在静息状态和配体结合状态下的结构 | Notti, R. Q. | N/A | The resting and ligand-bound states of the membrane-embedded human T-cell receptor-CD3 complex | |
| UGGT1介导的N-糖基化与不稳定的和错误折叠的糖蛋白的ER相关降解相竞争 | Ninagawa, S. | N/A | UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins | |
| 在不同啮齿动物杂交中，不同的复杂调控表型是导致杂交雄性不育的根源。 | Hunnicutt, K. E. | N/A | Different complex regulatory phenotypes underlie hybrid male sterility in divergent rodent crosses | |
| 在人类大脑进化和疾病过程中，KRAB锌指基因和转座子的调控网络发生了变化。 | Chen, Y.-C. | N/A | Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease | |
| 利用信息几何对细胞表型过渡流形进行几何量化 | Huang, M. | N/A | Geometric Quantification of Cell Phenotype Transition Manifolds with Information Geometry | |
| 在蛋白质结构约束下的基因重复功能多样化 | Guo, K. | N/A | Functional Diversification of Gene Duplicates under the Constraint of Protein Structure | |
| 比较单细胞分析揭示了胎儿-母体界面细胞类型和细胞信号创新的复杂模式 | Stadtmauer, D. J. | N/A | Comparative single cell analysis reveals complex patterns of cell type and cell signaling innovations at the fetal-maternal interface | |
| 伏隔核内侧壳中的胃泌素释放肽信号调节神经元兴奋性和动机 | Aisenberg, E. E. | N/A | Gastrin-releasing peptide signaling in the nucleus accumbens medial shell regulates neuronal excitability and motivation | |
| 药物诱导的p53激活限制了胰腺癌的启动 | Twardowski, J. J. | N/A | Drug-Induced p53 Activation Limits Pancreatic Cancer Initiation | |
| 加拉帕戈斯黄莺在应对交通噪音的行为可塑性方面，因与道路的距离不同而有所差异。 | Hohl, L. | N/A | Galapagos yellow warblers differ in behavioural plasticity in response to traffic noise depending on proximity to road. | |
| 开发辣椒素衍生物作为抑制素配体，以调节癌细胞中的Aurora激酶A/PHB2相互作用 | Djehal, A. | N/A | Development of capsaicin derivatives as prohibitin ligands to modulate the Aurora kinase A/PHB2 interaction in cancer cells | |
| 单等位基因表观遗传调控布氏锥虫中RNA聚合酶II多顺反子转录起始的双向沉默。 | Kieft, R. | N/A | Mono-allelic epigenetic regulation of bi-directional silencing of RNA Polymerase II polycistronic transcription initiation in Trypanosoma brucei. | |
| 单核RNA测序揭示了纹状体小胶质细胞中急性应激和慢性运动的持久特征 | Connolly, M. G. | N/A | Single-nucleus RNA sequencing reveals enduring signatures of acute stress and chronic exercise in striatal microglia | |
| 从人类多能干细胞可扩展地分化出下丘脑弓状核神经元，适用于代谢和生殖障碍的模型构建 | Jovanovic, V. M. | N/A | Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders | |
| 鲁棒的结合能力和端粒结合蛋白的丧失是端粒重复基序进化的基础 | Song, H. | N/A | Robust Binding Capability and Loss of Telomere-Binding Proteins Underlying the Evolution of Telomeric Repeat Motifs | |
| 一种即时语音合成神经假体 | Wairagkar, M. | N/A | An instantaneous voice synthesis neuroprosthesis | |
| 评估预测哺乳动物皮层细胞类型特异性增强子的方法 | Johansen, N. J. | N/A | Evaluating Methods for the Prediction of Cell Type-Specific Enhancers in the Mammalian Cortex | |
| 高通量无监督量化模式在狨猴自然行为中的应用 | Menegas, W. | N/A | High-throughput unsupervised quantification of patterns in the natural behavior of marmosets | |
| 外来入侵物种的灭绝潜力 | Philippe-Lesaffre, M. | N/A | Extinction potential from invasive alien species | |
| 促性腺激素细胞具有双重起源，其中大多数在微青春期期间由垂体干细胞分化而来。 | Sheridan, D. | N/A | Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty. | |
| 肌梭为运动序列提供灵活的感觉反馈。 | Olson, W. P. | N/A | Muscle spindles provide flexible sensory feedback for movement sequences | |
| RCoxNet：一种集成随机游走重启与突变及临床数据的癌症生存预测深度学习框架 | Kumari, S. | N/A | RCoxNet: deep learning framework for enhanced cancer survival prediction integrating random walk with restart with mutation and clinical data | |
| metagWGS，一个利用Illumina或PacBio HiFi读取数据进行宏基因组数据分析的综合工作流程 | Mainguy, J. | N/A | metagWGS, a comprehensive workflow to analyze metagenomic data using Illumina or PacBio HiFi reads | |
| 在反思室和VR头戴设备环境中，对比呼吸练习与自然主义刺激对认知、行为和生理反应的影响：随机对照研究 | Simonian, N. | N/A | Contrasting Cognitive, Behavioral, and Physiological Responses to Breathwork vs. Naturalistic Stimuli in Reflective Chamber and VR Headset Environments: Randomized Control Study | |
| 通过ER-Hoxb8条件性永生化巨噬细胞替代小胶质细胞，为深入了解Aicardi-Goutieres综合征的神经病理学提供了新的视角。 | Nemec, K. M. | N/A | Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutieres Syndrome neuropathology | |
| 制造感知的生成模型架构能够实现生物序列的设计和合成，规模达到千万亿级 | Weinstein, E. N. | N/A | Manufacturing-Aware Generative Model Architectures Enable Biological Sequence Design and Synthesis at Petascale | |
| 氧化应激的隔离是必要的，但不足以得出姜黄素对多巴胺能神经的保护作用：来自ALSS果蝇帕金森病模型的见解 | Phom, L. | N/A | Sequestration of oxidative is necessary but not sufficient enough to conclude dopaminergic neuroprotective efficacy of curcumin: Insights from ALSS Drosophila Parkinson disease model | |
| 结构系统发育学的一般替代矩阵。 | Garg, S. G. | N/A | A general substitution matrix for structural phylogenetics. | |
| 使用质粒分析服务进行高效且经济的长时间读取扩增子测序：应用于日本牵牛花中的转座子插入等位基因 | Nakagawa, S. | N/A | Labor- and cost-effective long-read amplicon sequencing using a plasmid analysis service: Application to transposon-inserted alleles in Japanese morning glory | |
| 对CLAP数据的重新分析证实了PRC2是一种RNA结合蛋白。 | Lee, Y. | N/A | Re-analysis of CLAP data affirms PRC2 as an RNA binding protein | |
| 泛基因组启发的语言模型用于隐私保护的合成基因组序列生成 | Huang, P. | N/A | Pangenome-Informed Language Models for Privacy-Preserving Synthetic Genome Sequence Generation | |
| SoyOD：一个综合的大豆多组学数据库，用于挖掘基因和生物学研究 | Li, J. | N/A | SoyOD: An Integrated Soybean Multi-omics Database for Mining Genes and Biological Research | |
| 功能连接主要由非周期性的耦合，而非振荡性的耦合所主导。 | Monchy, N. | N/A | Functional connectivity is dominated by aperiodic, rather than oscillatory, coupling | |
| InTraSeq：一种揭示新型单细胞生物学和调控机制的多模态分析方法 | Ariss, M. M. | N/A | InTraSeq: A Multimodal Assay that Uncovers New Single-Cell Biology and Regulatory Mechanisms | |
| 磷酸化诱导的SUMO化促进Ulk4在纤毛尖端的凝聚，以转导Hedgehog信号 | Zhou, M. | N/A | Phosphorylation-induced SUMOylation promotes Ulk4 condensation at ciliary tip to transduce Hedgehog signal | |
| 细胞器向内运输推动纺锤体在秀丽隐杆线虫减数分裂期间向外迁移 | Peraza, A. A. | N/A | Inward transport of organelles drives outward migration of the spindle during C. elegans meiosis | |
| 如何构建eDNA定制条形码参考库的最佳实践？以澳大利亚地下动物为例的研究。 | Guzik, M. | N/A | What are the best practices for curating eDNA custom barcode reference libraries? A case study using Australian subterranean fauna. | |
| 对“蛋白质序列景观并不那么简单：关于无参考与基于参考推断”的回应 | Park, Y. | N/A | Response to "Protein sequence landscapes are not so simple: on reference-free versus reference-based inference" | |
| 染色体外DNA与核凝聚物相关联，并通过重组染色质结构来增强致癌转录 | Taghbalout, A. | N/A | Extrachromosomal DNA Associates with Nuclear Condensates and Reorganizes Chromatin Structures to Enhance Oncogenic Transcription | |
| 将全长FLT1表达重定向至其可溶性异构体可促进缺血后血管生成 | Bundalo, M. | N/A | Redirecting full-length FLT1 expression towards its soluble isoform promotes postischemic angiogenesis | |
| 用泛扩张显微镜可视化核孔复合体的可塑性 | Morgan, K. J. | N/A | Visualizing nuclear pore complex plasticity with Pan-Expansion Microscopy | |
| 二硫键介导的TRAP1四聚化促进了其抗氧化和促肿瘤活性。 | Faienza, F. | N/A | Disulfide-mediated tetramerization of TRAP1 fosters its antioxidant and pro-neoplastic activities. | |
| 通过地理信息学捕捉盐沼地下生物量的时空变化，这是关键的恢复力指标。 | Runion, K. D. | N/A | Capturing spatiotemporal variation in salt marsh belowground biomass, a key resilience metric, through geoinformatics | |
| 不仅仅是果香：十二种番荔枝科植物的花部生物学、香气与光谱反射率 | Liu, M.-F. | N/A | More than fruity scents: floral biology, scent and spectral reflectance of twelve Annonaceae species | |
| 揭示西尼罗病毒传播的温度敏感性：蚊媒病原体性状响应的新型计算方法 | Heidecke, J. | N/A | Disclosing temperature sensitivity of West Nile virus transmission: novel computational approaches to mosquito-pathogen trait responses | |
| AusAMF：澳大利亚丛枝菌根真菌群落数据库 | Frew, A. | N/A | AusAMF: database of arbuscular mycorrhizal fungal communities in Australia | |
| 宿主异质性对流行病动态的影响取决于宿主传染性是如何确定的。 | Cohen, J. A. | N/A | Effects of host heterogeneity on epidemiological dynamics are mediated by how host infectiousness is determined | |
| 树种多样性降低温带森林病原体损害：一项系统综述与元分析 | Field, E. | N/A | Tree diversity reduces pathogen damage in temperate forests: a systematic review and meta-analysis | |
| 鱼类环境RNA测序通过短期水族箱采样灵敏地捕捉累积应激反应 | Miyata, K. | N/A | Fish environmental RNA sequencing sensitively captures accumulative stress responses through short-term aquarium sampling | |
| 转录后调控IFI16促进在肺动脉高压中观察到的炎症性内皮病理表型 | Rao, R. J. | N/A | Post-transcriptional regulation of IFI16 promotes inflammatory endothelial pathophenotypes observed in pulmonary arterial hypertension | |
| 大麻哈鱼虱（Lepeoptheirus salmonis）在斑点鲽（Cyclopterus lumpus）体内的消化时间与新鲜度、发育阶段及温度相关。 | Eliasen, K. | N/A | The digestion time for salmon louse (Lepeoptheirus salmonis) in lumpfish (Cyclopterus lumpus) in relation to freshness, developmental stage, and temperature | |
| 全球基因型与环境预测竞赛揭示出，多样化的建模策略能够提供令人满意的玉米产量估算 | Washburn, J. D. | N/A | Global Genotype by Environment Prediction Competition Reveals That Diverse Modeling Strategies Can Deliver Satisfactory Maize Yield Estimates | |
| 两种海蛄虾物种Echinogammarus marinus和Gammarus pulex在夜间光照水平逐渐增加下的行为节律 | Underwood, C. N. | N/A | Behavioural rhythms of two gammarid species Echinogammarus marinus and Gammarus pulex under increasing levels of light at night | |
| 用于低剂量率瘤内放射治疗的掺钇-90金属有机框架（MOFs） | Qi, X. | N/A | Yttrium-90-doped metal-organic frameworks (MOFs) for low-dose rate intratumoral radiotherapy | |
| 通过在玻片上使用Mucinase StcE进行消化，对MUC2糖肽进行糖基位点映射和原位质谱成像 | Lowery, S. C. | N/A | Glycosite Mapping and in situ Mass Spectrometry Imaging of MUC2 Glycopeptides via On-slide Digestion with Mucinase StcE | |
| 在拟南芥中，双酰胺的形成需要与DPH1相互作用的DPH2，以实现对光和氧化应激的抗性。 | Kraemer, U. | N/A | Diphthamide formation in Arabidopsis requires DPH1-interacting DPH2 for light and oxidative stress resistance | |
| 新型调节因子Fpr2通过依赖于CCL4的中性粒细胞控制免疫稳态 | Mei, S. | N/A | Novel regulator Fpr2 controls immune homeostasis via CCL4-dependent neutrophils | |
| 单纯疱疹病毒在感染小鼠皮肤后的组装与扩散 | Richardo, T. | N/A | Herpes Simplex Virus Assembly and Spread in murine skin after infection from the outside | |
| 通过3,034个基因组的视角概述酿酒酵母的种群结构 | Loegler, V. | N/A | Overview of the Saccharomyces cerevisiae population structure through the lens of 3,034 genomes | |
| 细菌和酵母表达系统中植物类病毒颗粒形成的研究 | Balke, I. | N/A | Investigation of plant virus-like particle formation in bacterial and yeast expression systems | |
| 中枢突触前末梢通过限制再循环池密度来调节自发突触囊泡胞吐速率 | Wilson, P. | N/A | Central Presynapses Regulate Spontaneous Synaptic Vesicle Exocytosis Rate by Constraining Recycling Pool Density | |
| Cytoophidium复合物与细胞命运产生共鸣 | Li, Y.-L. | N/A | Cytoophidium complexes resonate with cell fates | |
| 通过数学建模理解组织金属蛋白酶抑制剂对慢性伤口调节的作用 | Dari, S. | N/A | Understanding the regulation of chronic wounds by tissue inhibitors of matrix metalloproteinases through mathematical modelling | |
| 关键物种对全球引入的强毒病原体的快速适应 | Cassin-Sackett, L. | N/A | Rapid adaptation to a globally introduced virulent pathogen in a keystone species | |
| 葡甘露聚糖工程突显了半乳糖基化修饰在微调拟南芥细胞壁中纤维素-葡甘露聚糖相互作用中的作用。 | Yoshimi, Y. | N/A | Glucomannan engineering highlights the role of galactosyl modification in fine-tuning cellulose-glucomannan interaction in Arabidopsis cell walls | |
| 聚集的巨噬细胞通过协调的入侵泡合作消除肿瘤。 | Dooling, L. J. | N/A | Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia | |
| 网络驱动的不可苏拉姆新底物识别，用于靶向蛋白质降解 | Jarnuczak, A. F. | N/A | Network-driven identification of indisulam neo-substrates for targeted protein degradation | |
| Fusobacterium nucleatum通过三聚自转运粘附素CbpF与免疫细胞结合的结构基础 | Marongiu, G. L. | N/A | Structural basis for immune cell binding of Fusobacterium nucleatum via the trimeric autotransporter adhesin CbpF | |
| 一种用于生理条件下适冷物种生物学研究的高分辨率显微系统 | Marty, A.-P. M. | N/A | A high-resolution microscopy system for biological studies of cold-adapted species under physiological conditions | |
| 单分子多重寿命成像与门控单光子相机 | Ronceray, N. | N/A | Multiplexed lifetime imaging of single molecules with a gated single-photon camera | |
| 聚焦镓离子束的生物体积电子显微镜依赖于在断面形成抗辐射的富镓层。 | Yang, Z. | N/A | Biological volume EM with focused Ga ion beam depends on formation of radiation-resistant Ga-rich layer at block face | |
| 通过HLA I类分子识别儿童脑瘤细胞表面呈现的天然寨卡病毒肽段 | Sherwood, M. | N/A | Identification of natural Zika virus peptides presented on the surface of paediatric brain tumour cells by HLA classI | |
| 利用先验生物学知识推断和聚类突变特征的贝叶斯框架。 | Buscaroli, E. | N/A | A Bayesian framework to infer and cluster mutational signatures leveraging prior biological knowledge. | |
| 急性髓系白血病中的PTPN11突变克隆层次结构 | Fobare, S. | N/A | PTPN11 Mutation Clonal Hierarchy in Acute Myeloid Leukemia | |
| 15q11.2缺失相关神经发育障碍的人类神经元模型中的发育改变和网络连接性变化 | Habela, C. W. | N/A | Altered development and network connectivity in a human neuronal model of 15q11.2 deletion-related neurodevelopmental disorders | |
| O-GlcNAc糖基化水平升高对齿状回中线粒体自噬和小胶质细胞的影响 | Kramer, J. | N/A | Impact of O-GlcNAcylation elevation on mitophagy and glia in the dentate gyrus | |
| 小鼠中蛋白质O-GlcNAc糖基化的急性增加导致大脑转录组变化，这与在阿尔茨海默病中观察到的相反。 | Bell, M. | N/A | Acute increase of protein O-GlcNAcylation in mice leads to transcriptome changes in the brain opposite to what is observed in Alzheimer Disease | |
| Sca-1表达描绘了在稳态和病理条件下的小鼠中性粒细胞的促炎状态。 | Nahiyera, M. | N/A | Sca-1 expression depicts pro-inflammatory murine neutrophils under steady state and pathological conditions | |
| DNA-PK 调控环二核苷酸相关的一型干扰素反应 | taffoni, c. | N/A | DNA-PK controls cyclic dinucleotide-associated type I Interferon responses | |
| 一项邻近连接分析筛选出SNAT2作为MARCH1 E3泛素连接酶的新型靶标 | Balthazard, R. | N/A | A proximity ligation screen identifies SNAT2 as a novel target of the MARCH1 E3 ubiquitin ligase | |
| 植物逆转了养分添加对土壤多功能性抗旱性的积极影响 | Piton, G. | N/A | Plants reverse the positive effect of nutrient addition on the drought resistance of soil multifunctionality | |
| 高通量氨基酸水平分析纤溶酶原激活剂抑制剂-1与不同变异蛋白酶相互作用的研究 | Haynes, L. M. | N/A | High-throughput amino acid-level characterization of the interactions of plasminogen activator inhibitor-1 with variably divergent proteases | |
| 对一种极度濒危软体动物的突变率及其进化后果的直接测量 | Wooldridge, B. | N/A | Direct measurement of the mutation rate and its evolutionary consequences in a critically endangered mollusk | |
| 酵母基因组数据库：基因组注释的进展、扩展的生化途径以及其他关键增强功能 | Engel, S. R. | N/A | Saccharomyces Genome Database: Advances in Genome Annotation, Expanded Biochemical Pathways, and Other Key Enhancements | |
| 肝细胞癌的表观基因组分析揭示了异常的顺式调控变化和失调的逆转录转座子，这些变化具有预后潜力。 | Cheng, C. C. Y. | N/A | Epigenomic analysis of hepatocellular carcinoma reveals aberrant cis-regulatory changes and dysregulated retrotransposons with prognostic potentials | |
| 一种新型高特异性和可溶性蛋白酶，用于精确去除N端纯化标签 | Shams, R. | N/A | A new highly specific and soluble protease for precise removal of N-terminal purification tags | |
| Palmatine与DNA的主要结合模式 | Gentile, M. | N/A | The predominant binding mode of Palmatine to DNA | |
| 先天免疫受体NLRX1：胶质母细胞瘤病理生理学的潜在调节因子 | Meena, D. | N/A | Innate Immune Receptor NLRX1: Potential Modulator of Glioblastoma Pathophysiology | |
| 引发剂对橡树幼苗防御白粉病的特异性机制 | Sanchez-Lucas, R. | N/A | Elicitor specific mechanisms of defence priming in oak seedlings against powdery mildew | |
| 优化小鼠血脑屏障血管的富集，重点聚焦于采集后分析中的网络层次结构 | Abdelazim, H. | N/A | Optimized Enrichment of Murine Blood-Brain Barrier Vessels with a Critical Focus on Network Hierarchy in Post-Collection Analysis | |
| 牛血液树突状细胞和单核细胞亚群中XCR1、CX3CR1、CSF1R和ADGRE1的表达 | Talker, S. C. | N/A | Expression of XCR1, CX3CR1, CSF1R and ADGRE1 on subsets of bovine blood dendritic cells and monocytes | |
| 极端微生物固定化核苷2'-脱氧核糖基转移酶用于核苷生物催化 | Hernandez Martinez, S. A. | N/A | Immobilized Nucleoside 2'-Deoxyribosyltransferases from Extremophiles for Nucleoside Biocatalysis | |
| 潜在的癌症生物标志物：有丝分裂期DNA损伤检查点基因 | Agarwal, K. | N/A | Potential Cancer Biomarkers: Mitotic Intra-S DNA Damage Checkpoint Genes | |
| scaLR：一个基于低资源深度神经网络的单细胞分析与生物标志物发现平台 | Jogani, S. | N/A | scaLR: a low-resource deep neural network-based platform for single cell analysis and biomarker discovery | |
| 基于花序逆转的日中性大麻（Cannabis sativa L.）微繁殖技术 | Tabatabaei, D. S. | N/A | Floral Reversion based micropropagation of Day-Neutral Cannabis sativa L. | |
| 专业学会支持的生物学教育DEI研究的系统综述：该领域的研究群体、研究方法及分析层次 | Idlebird, C. | N/A | A systematic review of professional society-backed biology education DEI research: The groups, research methods, and levels of analyses comprising the field | |
| 随机獾扑杀试验缺乏主动獾扑杀对牛结核病影响的证据：对Mills等人2024年研究（第一部分与第二部分）的评论 | Torgerson, P. | N/A | Randomised Badger Culling Trial lacks evidence for proactive badger culling effect on tuberculosis in cattle: comment on Mills et al. 2024, Parts I & II | |
| 血管性认知障碍机制及相互作用的一个以炎症为中心的视角 | Zeylan, M. E. | N/A | An Inflammation Centered Perspective to the Mechanisms and Interactions Related to Vascular Cognitive Impairment | |
| BrainUnit：将物理单位融入高性能AI驱动的科学计算 | Wang, C. | N/A | BrainUnit: Integrating Physical Units into High-Performance AI-Driven Scientific Computing | |
| 早期精神分裂症中的静息态超连接和低连接：我们应该关注冰山的哪一角？ | Tomecek, D. | N/A | Resting-state hyper- and hypo-connectivity in early schizophrenia: which tip of the iceberg should we focus on? | |
| 器官特异性交感神经支配定义了内脏功能 | Wang, T. | N/A | Organ-specific Sympathetic Innervation Defines Visceral Functions | |
| 从功能性磁共振成像数据解码参数化抓握力预期 | Caccialupi, G. | N/A | Decoding Parametric Grip-Force Anticipation from fMRI-Data | |
| 特征基因揭示了小鼠和鱼类大脑发育过程中不变的全球空间模式 | Kerstjens, S. | N/A | Eigengene reveals invariant global spatial patterns across mouse and fish brain development | |
| 增加早期内体适配器APPL1的神经元表达会导致内体和突触功能障碍，伴随胆碱能神经退化。 | Jiang, Y. | N/A | Increased neuronal expression of the early endosomal adaptor APPL1 leads to endosomal and synaptic dysfunction with cholinergic neurodegeneration | |
| 社会结构对和尚鹦鹉发声灵活性的影响 | Smeele, S. Q. | N/A | The effect of social structure on vocal flexibility in monk parakeets | |
| 传入感觉噪声对连续吸引子网络模型中网格状放电和路径整合的双重影响 | Nagaraj, H. | N/A | Dichotomous impact of afferent sensory noise on grid-patterned firing and path integration in a continuous attractor network model | |
| 哺乳动物视网膜双极细胞：兔视网膜的形态学鉴定与系统分类，并进行比较视角的探讨 | Famiglietti, E. V. | N/A | Mammalian Retinal Bipolar Cells: Morphological Identification and Systematic Classification in Rabbit Retina, with a Comparative Perspective | |
| 证据表明Dmrta2在小鼠皮层祖细胞中作为Pax6的转录抑制因子，并鉴定出与人类小头畸形相关的关键DNA识别突变 | Shen, X. | N/A | Evidence that Dmrta2 acts as a transcriptional repressor of Pax6 in murine cortical progenitors and identification of a mutation crucial for DNA recognition associated with microcephaly in human | |
| 毛细血管尺度的微血管成像：高频超声定位显微镜在小鼠大脑中的应用 | Lowerison, M. | N/A | Capillary-scale Microvessel Imaging with High-frequency Ultrasound Localization Microscopy in Mouse Brain | |
| 模式化的无线经颅光遗传学技术能够产生人工感知 | Wu, M. | N/A | Patterned wireless transcranial optogenetics generates artificial perception | |
| 猕猴腹侧顶内皮层的功能连接模式揭示了一种前-后向的特化，类似于人类腹侧顶内皮层区域所描述的特征。 | Sheng, W.-A. | N/A | The macaque ventral intraparietal functional connectivity patterns reveal an anterio-posterior specialization mirroring that described in human ventral intraparietal area | |
| 出生后前六个月大脑网络的空间发展 | Seraji, M. | N/A | Spatial Development of Brain Networks During The First Six Postnatal Months | |
| 活体脑片中模拟缺血通过打开Na+/K+泵来模拟：对扩散性去极化生成的线索。 | Kim, D. | N/A | Simulated ischemia in live cerebral slices is mimicked by opening the Na+/K+ pump: clues to the generation of spreading depolarization. | |
| T1234：一种针对高分辨率fMRI数据配准错误的畸变匹配结构扫描解决方案 | Kan, C. | N/A | T1234: A distortion-matched structural scan solution to misregistration of high resolution fMRI data | |
| 探索同步的边缘：慢波侵蚀了行为猴子的静息活动 | Pazienti, A. | N/A | Probing the edge of synchronization: Slow waves erode resting activity in behaving monkeys | |
| 动脉自旋标记灌注磁共振成像分析用于人类连接组项目生命周期老化与发展研究 | Kirk, T. F. | N/A | Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies | |
| 神经元脂滴在维持全身能量稳态中发挥着保守且性别偏向的作用。 | Manceau, R. | N/A | Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis | |
| 僵直性清醒巩固：10赫兹重复视觉刺激增强视觉学习的离线增益 | Yang, X.-Y. | N/A | Tetanizing wakeful consolidation: ten-hertz repetitive visual stimulation enhances the offline gain of visual learning | |
| 人类多巴胺能神经元携带LRRK2 G2019S突变的细胞内和细胞外蛋白质组特征 | Knab, F. | N/A | The Cellular and Extra-Cellular Proteomic Signature of Human Dopaminergic Neurons Carrying the LRRK2 G2019S Mutation | |
| 在人类多巴胺能神经元中的形态学分析表明，线粒体解偶联具有神经保护作用。 | Gorgogietas, V. | N/A | Morphological profiling in human dopaminergic neurons identifies mitochondrial uncoupling as a neuroprotective effect | |
| 在皮质发育过程中对Emx2和Dmrta2合作的新见解以及Dmrta2在脉络丛功能中的证据 | Anirudhan, J. | N/A | Novel insights into Emx2 and Dmrta2 cooperation during cortex development and evidence for Dmrta2 function in choroid plexus | |
| 通过融合远端肾单位与输尿管芽，将收集系统整合入肾脏类器官。 | Shi, M. | N/A | Integrating collecting systems in kidney organoids through fusion of distal nephron to ureteric bud. | |
| 调节DNA Polα可增强跨物种细胞重编程 | Ranjan, R. | N/A | Modulating DNA Polα Enhances Cell Reprogramming Across Species | |
| 社交隔离加剧斑马鱼中adgrl3.1相关的外化和内化行为 | Fontana, B. D. | N/A | Social Isolation Intensifies adgrl3.1-Related Externalizing and Internalizing Behaviors in Zebrafish | |
| 一种基于沙漠蚂蚁（Melophorus bagoti）导航行为的心理物理学视觉方法 | deeti, s. | N/A | A Method for Visual Psychophysics based on the Navigational Behaviour of Desert Ants (Melophorus bagoti) | |
| 人类结构组合泛化的一种神经机制 | Luettgau, L. | N/A | A neural mechanism for compositional generalization of structure in humans | |
| 在少数活跃神经元的情况下，群体编码中的偏差 | Keemink, S. W. | N/A | Biases in population codes with a few active neurons | |
| 运动诱导的保留运动表现不伴有神经保护作用的小鼠帕金森病模型 | Skelton, H. M. | N/A | Exercise Evokes Retained Motor Performance without Neuroprotection in a Mouse Model of Parkinson's Disease | |
| 人类视觉运动区域FST的功能定位 | Wen, P. | N/A | Functional localization of visual motion area FST in humans | |
| 染色质重塑因子BRG1招募亨廷顿蛋白修复神经元中的DNA双链断裂 | Pradhan, S. | N/A | Chromatin remodeler BRG1 recruits huntingtin to repair DNA double-strand breaks in neurons | |
| 一个统一的啮齿动物图谱揭示了背侧迷走复合体的细胞复杂性和进化分歧 | Hes, C. | N/A | A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex | |
| 海马体中的γCaMKII多巴胺化促进了突触到核的信号传导和记忆形成 | Stewart, A. F. | N/A | Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation | |
| IGF-1和胰岛素受体在LepRb神经元中共同调节身体生长、骨质量、生殖和代谢。 | Wang, M. | N/A | IGF-1 and insulin receptors in LepRb neurons jointly regulate body growth, bone mass, reproduction, and metabolism | |
| 米诺环素和N-乙酰半胱氨酸增加蛋白激酶Mζ表达，恢复小鼠闭合性脑损伤后的晚期长时程增强效应和空间学习能力 | Nikulina, E. | N/A | Increased protein kinase Mζ expression by Minocycline and N-acetylcysteine restoreslate-phase long-term potentiation and spatial learning after closed head injury in mice | |
| 脊髓横断与运动速度对猫后肢肌肉协同作用的影响 | Klishko, A. | N/A | EFFECTS OF SPINAL TRANSECTION AND LOCOMOTOR SPEED ON MUSCLE SYNERGIES OF THE CAT HINDLIMB | |
| 通过无监督分割和聚类惯性信号对啮齿动物行为进行精细分解 | Fayat, R. | N/A | Fine decomposition of rodent behavior via unsupervised segmentation and clustering of inertial signals | |
| 工作记忆预测听觉序列的长期识别：已验证预测与预测误差之间的分离 | Bonetti, L. | N/A | Working memory predicts long-term recognition of auditory sequences: Dissociation between confirmed predictions and prediction errors | |
| 血红蛋白α是一种氧化还原敏感的线粒体相关蛋白，存在于T淋巴细胞中。 | Reed, E. C. | N/A | Hemoglobin alpha is a redox-sensitive mitochondrial-related protein in T-lymphocytes | |
| ICOS限制了耗竭PD-1+ CD8 T细胞的记忆样特性和功能 | Humblin, E. | N/A | ICOS limits memory-like properties and function of exhausted PD-1+ CD8 T cells | |
| 从摄取膨胀聚苯乙烯的黄粉虫幼虫（鞘翅目：拟步甲科）肠道中分离出的肺炎克雷伯菌 | Caruajulca-Marin, L. | N/A | Klebsiella pneumoniae isolated from the intestines of Tenebrio molitor larvae (Coleoptera: Tenebrionidae) that consume expanded polystyrene | |
| 揭示铜绿假单胞菌对亚胺培南耐药性的蛋白质组学图谱：临床菌株与对照菌株的比较研究 | Eidsaa, M. | N/A | Unravelling the Proteomic Landscape of Imipenem Resistance in Pseudomonas aeruginosa: A Comparative Investigation between Clinical and Control Strains | |
| 1 白腿虾养殖中生产力的微生物组决定因素 | Shan, X. | N/A | 1 Microbiome determinants of productivity in whiteleg shrimp aquaculture | |
| 猴痘病毒蛋白质组的全面突变景观分析 | Ozaktas, T. | N/A | Comprehensive Mutational Landscape Analysis of Monkeypox Virus Proteome | |
| Mpox mRNA-1769疫苗抑制正痘病毒在鼻内、直肠和皮内接种部位的复制 | Cotter, C. A. | N/A | Mpox mRNA-1769 Vaccine Inhibits Orthopoxvirus Replication at Intranasal, Intrarectal, and Cutaneous Sites of Inoculation | |
| 5'和3' UTRs在SARS-CoV-2基因组包装中的作用 | Zhang, Z. | N/A | Involvement of 5' and 3' UTRs on SARS-CoV-2 Genome Packaging | |
| 化学修饰核苷类似物对SARS-CoV-2 RNA聚合酶的链终止效应 | Yang, L. | N/A | Chain Termination Effects of Chemically Modified Nucleoside Analogs on SARS-CoV-2 RNA Polymerase | |
| MdLRR-RLK1-MdATG3模块通过自噬增强苹果对非生物胁迫的抗性 | Chen, W.-J. | N/A | MdLRR-RLK1-MdATG3 module enhances the resistance of apples to abiotic stress via autophagy | |
| 深度学习揭示了多模板PCR中序列特异性扩增偏倚 | Gimpel, A. L. | N/A | Deep learning uncovers sequence-specific amplification bias in multi-template PCR | |
| 尿液蛋白质组中的病毒片段：发热病因的新线索 | Gao, Y. | N/A | Viral fragments in the urine proteome: New clues to the cause of fever | |
| 外生菌根真菌黄孢乳牛肝菌（Suillus luteus）在原生和引入种群中的生物合成基因簇多样性 | Allen, B. M. | N/A | Biosynthetic Gene Cluster Diversity Across Native and Introduced Populations of an Ectomycorrhizal Fungus, Suillus luteus | |
| 野生环境中个体和群体社会行为的分级选择 | Philson, C. S. | N/A | Multilevel selection on individual and group social behaviour in the wild | |
| 来自木质纤维素影响环境的高质量Bathyarchaeia宏基因组组装基因组揭示了代谢和进化机制。 | Nesbo, c. L. | N/A | High quality Bathyarchaeia MAGs from lignocellulose-impacted environments elucidate metabolism and evolutionary mechanisms. | |
| 谷氨酸激酶的纤维化及脯氨酸抑制作用 | Zhang, T. | N/A | Filamentation and proline inhibition of glutamate kinase | |
| 动态金属配位调控自由基卤化酶的化学选择性 | Kissman, E. N. | N/A | Dynamic metal coordination controls chemoselectivity in radical halogenases | |
| 从大肠杆菌中高效生产功能性前溶菌素 | Pham, Q. | N/A | Efficient production of functional proaerolysin from E.coli | |
| 一个内在无序的RNA结合区域提供了局部目标选择性，并且对LARP6的功能至关重要。 | Capraro, F. | N/A | An intrinsically disordered RNA-binding region provides local target selectivity and is essential for LARP6 function. | |
| 鉴定出胱氨酸代谢调控因子（CymR）衍生的五肽作为金黄色葡萄球菌O-乙酰-ʟ-丝氨酸硫醇酶（CysK）的纳摩尔抑制剂 | Pederick, J. L. | N/A | Identification of cysteine metabolism regulator (CymR)-derived pentapeptides as nanomolar inhibitors of Staphylococcus aureus O-acetyl-ʟ-serine sulfhydrylase (CysK) | |
| 羊双心室心力衰竭中的三尖瓣不适应：后叶和间隔叶 | Kostelnik, C. J. | N/A | Tricuspid valve maladaptation in sheep with biventricular heart failure: The posterior and septal leaflets | |
| 设计和生物工程改造CDR，使其对SARS-CoV-2 Omicron变体的受体结合域（RBD）具有更高的亲和力 | Singh, V. | N/A | Designing and bioengineering of CDRs with higher affinity against receptor-binding domain (RBD) of SARS-CoV-2 Omicron variant | |
| TX-Phase：在可信执行环境中对私有基因组进行安全分阶段处理 | Dokmai, N. | N/A | TX-Phase: Secure Phasing of Private Genomes in a Trusted Execution Environment | |
| 通过调节ROCK克服癌细胞对OXPHOS抑制的代谢适应，并驱动协同的抗肿瘤活性 | Blazanin, N. | N/A | Therapeutic modulation of ROCK overcomes metabolic adaptation of cancer cells to OXPHOS inhibition and drives synergistic anti-tumor activity | |
| 长期饮食暴露于邻苯二甲酸盐混合物会增强雌激素和β-连环蛋白信号通路，导致小鼠子宫内膜增生。 | Shukla, R. | N/A | Long-term dietary exposure to a mixture of phthalates enhances estrogen and beta-catenin signaling pathways, leading to endometrial hyperplasia in mice | |
| 特定情境下基因组规模代谢模型的修改与分析：以甲烷利用微生物底盘为例 | Kulyashov, M. A. | N/A | Modification and Analysis of Context-Specific Genome-Scale Metabolic Models: Methane-Utilizing Microbial Chassis as a Case Study | |
| # BioRxiv 2024-09-19 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 一种由光触发的非经典平面细胞极性通路 | Housset, M. | N/A | A non-canonical planar cell polarity pathway triggered by light | |
| 一种宿主内感染模型，用于探究耐受性和抗性 | Duneau, D. | N/A | A within-host infection model to explore tolerance andresistance | |
| 一种探究宿主体内耐受性和抵抗力的感染模型 | Duneau, D. | N/A | A within-host infection model to explore tolerance andresistance | |
| 在恶性疟原虫感染的红细胞中，一个不寻常的MSRP6转运域定义了一个复杂结构，该结构对于Maurer裂隙的锚定和维持是必需的。 | Blancke Soares, A. | N/A | An unusual trafficking domain in MSRP6 defines a complex needed for Maurer's clefts anchoring and maintenance in P. falciparum infected red blood cells | |
| iTRVZ：用于整合细胞膜信号的纳米液态平台 | Tsunoyama, T. A. | N/A | iTRVZ: liquid nano-platform for signal integration on the plasma membrane | |
| 通过人类心室电机械建模和模拟解释急性与慢性梗塞的临床表型 | Zhou, X. | N/A | Clinical phenotypes in acute and chronic infarction explained through human ventricular electromechanical modelling and simulations | |
| 新型猪模型揭示肺发育和稳态过程中存在两种不同的LGR5细胞类型 | Polkoff, K. | N/A | Novel porcine model reveals two distinct LGR5 cell types during lung development and homeostasis | |
| 使用深度学习预测代谢物对饮食干预的反应 | Wang, T. | N/A | Predicting metabolite response to dietary intervention using deep learning | |
| 全基因组DNA修复蛋白的分析揭示了单细胞中更高层次的协调 | de Luca, K. L. | N/A | Genome-wide profiling of DNA repair proteins identifies higher-order coordination in single cells | |
| 视觉皮层中多个移动刺激的神经表征中双眼视差和注意力的作用 | Chakrala, A. S. | N/A | The role of binocular disparity and attention in the neural representation of multiple moving stimuli in the visual cortex | |
| 联想学习和非联想学习对防御行为动态的贡献 | Le, Q.-S. E. | N/A | Contributions of associative and non-associative learning to the dynamics of defensive ethograms | |
| 在巨型基因组植物黑种草（Nigella damascena L.）的异染色质复制过程中，全球核重组。 | Arifulin, E. | N/A | Global nuclear reorganization during heterochromatin replication in the giant-genome plant Nigella damascena L. | |
| 电影揭示了婴儿视觉皮层的精细结构 | Ellis, C. T. | N/A | Movies reveal the fine-grained organization of infant visual cortex | |
| 认知努力增加了奖励的强度。 | Wahab, M. | N/A | Cognitive effort increases the intensity of rewards | |
| 胎儿和成人胸腺中T细胞受体（TCR）基因片段的使用和MHC限制性存在明显差异。 | Rowell, J. | N/A | Distinct T Cell Receptor (TCR) gene segment usage and MHC-restriction between foetal and adult thymus | |
| 一种从延迟的消化后反馈中学习的神经机制 | Zimmerman, C. A. | N/A | A neural mechanism for learning from delayed postingestive feedback | |
| 鳞头松鸡和北鹑的关键繁殖行为受温度变化和平均温度的影响。 | Kirkpatrick, W. | N/A | Critical reproductive behaviors in Scaled Quail and Northern Bobwhite are affected by thermal variability and mean temperature | |
| p53通过关联基因组完整性和衰老相关炎症的相互调控 | Miller, K. N. | N/A | Linked regulation of genome integrity and senescence-associated inflammation by p53 | |
| 基于微生物组的随机误差校正方法，用于从自我报告的饮食评估中得出的营养素谱 | Wang, T. | N/A | Microbiome-based correction for random errors in nutrient profiles derived from self-reported dietary assessments | |
| 人类理性地适应对不确定性的近似估计。 | Pulcu, E. | N/A | Humans adapt rationally to approximate estimates of uncertainty | |
| 基准测试单个降解蛋白质的鉴定，以探索古代蛋白质的最佳搜索策略 | Rodriguez Palomo, I. | N/A | Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins | |
| 利用AlphaFold进行高通量发现抑制性蛋白质片段 | Savinov, A. | N/A | High-throughput discovery of inhibitory protein fragments with AlphaFold | |
| 基于假设的可解释神经网络用于基因间相互作用 | Wang, S. | N/A | Hypothesis-driven interpretable neural network for interactions between genes | |
| 基于假设的可解释神经网络，用于基因间相互作用 | Wang, S. | N/A | Hypothesis-driven interpretable neural network for interactions between genes | |
| 撒哈拉以南非洲地区疟原虫卵形体种群的基因组学研究 | Carey-Ewend, K. | N/A | Population genomics of Plasmodium ovale species in sub-Saharan Africa | |
| 一种用于研究疟原虫主要毒力因子功能研究的系统 | Cronshagen, J. | N/A | A system for functional studies of the major virulence factor of malaria parasites | |
| 细菌受体而非抗噬菌体防御机制决定了一对铜绿假单胞菌裂解噬菌体的宿主范围 | Mueller, D. M. | N/A | Bacterial Receptors but Not Anti-Phage Defence Mechanisms Determine Host Range for a Pair of Pseudomonas aeruginosa Lytic Phages | |
| 人类膀胱癌中自然杀伤细胞功能障碍是由组织特异性抑制SLAMF6信号传导引起的 | Farkas, A. M. | N/A | Natural Killer Cell Dysfunction In Human Bladder Cancer Is Caused By Tissue-Specific Suppression of SLAMF6 Signaling | |
| 与发育滞育的丧失相关的趋同进化可能会促进蜜蜂的寿命延长。 | Ferreira Santos, P. K. | N/A | Convergent evolution associated with the loss of developmental diapause may promote extended lifespan in bees | |
| 胎儿期接触酒精的幼儿，其大脑代谢和兴奋性的改变标志物与执行功能相关。 | Perdue, M. V. | N/A | Altered markers of brain metabolism and excitability are associated with executive functioning in young children exposed to alcohol in utero | |
| 纵向弯曲刚度和中底泡沫对跑步能量学的影响 | Perry, D. | N/A | Effects of longitudinal bending stiffness and midsole foam on running energetics | |
| 人类出生组织产品作为非阿片类药物抑制术后疼痛 | Zhang, C. | N/A | Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain | |
| 评估3xTg-AD小鼠海马中胶质细胞与神经元之间细胞间通讯在两个时间点的改变情况 | Soelter, T. M. | N/A | Evaluation of altered cell-cell communication between glia and neurons in the hippocampus of 3xTg-AD mice at two time points | |
| 人类诺如病毒在人类肠道类器官中培养的见解 | Ettayebi, K. | N/A | Insights into Human Norovirus Cultivation in Human Intestinal Enteroids | |
| 人类血液中携带有噬菌体组，其在克罗恩病中有所不同。 | Lamy-Besnier, Q. | N/A | The human blood harbors a phageome which differs in Crohn's disease | |
| 当环境发生变化时，候鸟会通过观察社会上的收益差异来学习。 | Chimento, M. | N/A | Immigrant birds learn from socially observed differences in payoffs when their environment changes | |
| 一种新型单体淀粉样β激活的信号通路通过抑制小胶质细胞调节大脑发育 | Kwon, H. | N/A | A novel monomeric amyloid β-activated signaling pathway regulates brain development via inhibition of microglia | |
| GeneSpectra：一种跨物种细胞类型基因表达的上下文感知比较方法 | Song, Y. | N/A | GeneSpectra: a method for context-aware comparison of cell type gene expression across species | |
| 贝叶斯系统发育自举法，应用于短树和分支 | Lemoine, F. | N/A | The Bayesian Phylogenetic Bootstrap, Application to Short Trees and Branches | |
| 在小鼠中对SV2A PET配体UCB-J的临床前验证和动力学建模 | Everix, L. | N/A | Preclinical validation and kinetic modelling of the SV2A PET ligand UCB-J in mice | |
| 社会气味促使海马CA2区位置细胞对社会刺激产生反应 | Robson, E. | N/A | Social odors drive hippocampal CA2 place cell responses to social stimuli | |
| 一个表示紧张动作电位尖峰列的数学序列 | Keum, D. | N/A | A Mathematical Sequence Representing Tonic Action Potential Spike Trains | |
| 距离预测的神经表征精度与算术表现相关 | Zhao, H. | N/A | Neural Representation Precision of Distance Predicts Arithmetic Performance | |
| 腹侧视觉通路中细粒度图像和类别信息的范围与限制 | Badwal, M. W. | N/A | The scope and limits of fine-grained image and category information in the ventral visual pathway | |
| 一种用于绘制活体人脑中微观水群和组织弛豫率的定量磁共振成像方法。 | Filo, S. | N/A | A qMRI approach for mapping microscopic water populations and tissue relaxivity in the in vivo human brain. | |
| 生物信息学家、计算机科学家和遗传学家领导生物信息工具开发 - 哪一个更好？ | Gardner, P. P. | N/A | A Bioinformatician, Computer Scientist, and Geneticist lead bioinformatic tool development - which one is better? | |
| "大分化者"属的系统基因组学揭示了岛屿系统中普遍存在的谱系不完全排序、基因流和线粒体捕获现象 | McCullough, J. | N/A | Phylogenomics of a genus of "Great Speciators" reveals rampant incomplete lineage sorting, gene flow, and mitochondrial capture in island systems | |
| 宿主与抗生素共同筛选出金黄色葡萄球菌更强的毒力 | Su, M. | N/A | Host and antibiotic jointly select for greater virulence in Staphylococcus aureus | |
| 临界性是大脑功能的统一设定点吗？ | Hengen, K. B. | N/A | Is criticality a unified set-point of brain function? | |
| 组胺干扰了小鼠的早期视觉处理 | Tripodi, M. | N/A | Histamine interferes with the early visual processing in mice | |
| 特定特征的除法归一化改进了深度感知中自然图像的编码 | Ni, L. | N/A | Feature-specific divisive normalization improves natural image encoding for depth perception | |
| 肩胛间棕色脂肪组织的交感神经支配并不是雄性饮食诱导的肥胖大鼠中OT引发的身体重量增加和脂肪减少的主要介质。 | Edwards, M. M. | N/A | Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats | |
| 对手在记忆回忆和视觉感知过程中，其视觉空间编码结构在中颞顶叶皮层中响应。 | Scrivener, C. L. | N/A | Opponent visuospatial coding structures responses during memory recall and visual perception in medial parietal cortex | |
| 功能性磁共振成像显示，在大鼠大脑进行五天的局部高密度θ波爆发刺激（hdTBS）后，脑部活动的区域性变化。 | Li, Q. | N/A | Functional MRI reveals regional changes of brain activity after five days of focal high-density theta burst stimulation (hdTBS) of the rat brain | |
| 通过DeepFuseNMF实现空间转录组学数据的可解释高分辨率降维 | Tang, J. | N/A | Interpretable high-resolution dimension reduction of spatial transcriptomics data by DeepFuseNMF | |
| pytom-match-pick：模板匹配中用于自动化分类的tophat-transform约束 | Chaillet, M. L. | N/A | pytom-match-pick: a tophat-transform constraint for automated classification in template matching | |
| 利用高分辨率基因表达谱揭示了被子植物中全基因组加倍后的保守进化响应 | Leal, J. L. | N/A | Conserved Evolutionary Response to Whole Genome Duplication in Angiosperms Revealed Using High Resolution Gene Expression Profiling | |
| 胞质CRISPR RNA用于RNA靶向CRISPR-Cas系统 | Cheng, E. C. K. | N/A | Cytosolic CRISPR RNA for RNA-targeting CRISPR-Cas systems | |
| 基于转录程序的MET外显子14跳跃调控网络解析 | Truong, M.-J. | N/A | Transcriptional program-based deciphering of the MET exon 14 skipping regulation network | |
| 一个从古代口腔微生物群中创建宏基因组组装基因组的高效流程 | Standeven, F. J. | N/A | An efficient pipeline for creating metagenomic-assembled genomes from ancient oral microbiomes | |
| 揭示细胞内Raf抑制剂敏感性的机制基础，揭示协同联合治疗策略 | Stoddard, E. G. | N/A | Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies | |
| 揭示细胞内Raf抑制剂敏感性的机制基础揭示了协同联合治疗策略 | Stoddard, E. G. | N/A | Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies | |
| 贾第鞭毛虫蛋白酶体盖的二元蛋白质相互作用图谱揭示了GlRpn11的额外蛋白酶体功能 | Das, A. | N/A | The binary protein interactome mapping of the Giardia lamblia proteasome lid reveals extra proteasomal functions of GlRpn11 | |
| 从头设计主动旋转和摆动的球形微泡 | Kaur, V. | N/A | De-novo design of actively spinning and gyrating spherical micro-vesicles | |
| 通过声波捕获进行生物聚合物凝聚物的机械表征 | Nakajima, K. | N/A | Mechanical Profiling of Biopolymer Condensates through Acoustic Trapping | |
| 在肾脏中，通过相关超分辨率光学和电子显微镜技术对白蛋白进行定位 | Birtasu, A. N. | N/A | Localization of Albumin with Correlative Super Resolution Light- and Electron Microscopy in the Kidney | |
| Hcm1的动态磷酸化在慢性应激中促进适应性 | Conti, M. M. | N/A | Dynamic phosphorylation of Hcm1 promotes fitness in chronic stress | |
| 细菌噬菌体在健康和克罗恩病中跨肠屏障的差异性易位 | Douadi, C. | N/A | Differential translocation of bacteriophages across the intestinal barrier in health and Crohn's disease | |
| 开发一种细胞通透性强的生物素-HaloTag配体，以探究蛋白质变体在细胞代际间的功能差异 | Yadav, A. K. | N/A | Development of a cell-permeable Biotin-HaloTag ligand to explore functional differences between protein variants across cellular generations | |
| 疾病状态在限制性迁移中的作用 | Meid, A. | N/A | The role of disease state in confined migration | |
| G蛋白偶联受体对mTORC1活性的底物特异性调控 | Atkinson, S. J. | N/A | Substrate-specific regulation of mTORC1 activity by G protein-coupled receptors | |
| RIPK1对于人类细胞中单纯疱疹病毒触发的依赖于ZBP1的坏死性凋亡是必不可少的。 | Amusan, O. T. | N/A | RIPK1 is essential for Herpes Simplex Virus-triggered ZBP1-dependent necroptosis in human cells | |
| CMK-1/CaMKI和TAX-6/Calcineurin在秀丽隐杆线虫的热回避回路中的拮抗作用，共同调控痛觉习惯化过程。 | Rudgalvyte, M. | N/A | Antagonist actions of CMK-1/CaMKI and TAX-6/Calcineurin along the C. elegans thermal avoidance circuit orchestrate nociceptive habituation | |
| 通过定量和行为学研究，揭示了秀丽隐杆线虫觅食过程中的接受-拒绝决策机制。 | Haley, J. A. | N/A | Accept-reject decision-making revealed via a quantitative and ethological study of C. elegans foraging | |
| 鼻内锂氯化物纳米颗粒抑制大脑炎症性细胞焦亡并改善5xFAD小鼠的记忆丧失和抑郁行为 | Bhuiyan, P. | N/A | Intranasal Lithium Chloride Nanoparticles Inhibit Inflammatory Pyroptosis in Brains and Ameliorate Memory Loss and Depression Behavior in 5xFAD mice | |
| 伏隔核星形胶质细胞双向调节社会行为 | VanRyzin, J. W. | N/A | Nucleus accumbens astrocytes bidirectionally modulate social behavior | |
| 皮层-海马相互作用是老年人基于图式的记忆编码的基础 | Huang, S. | N/A | Cortico-hippocampal interactions underlie schema-supported memory encoding in older adults | |
| 猕猴的前侧额叶皮层在不同的学习情境中引导决策 | Fujimoto, A. | N/A | Ventrolateral prefrontal cortex in macaques guides decisions in different learning contexts | |
| 神经元培养基中星形胶质细胞Nrf2的基础激活：神经元-星形胶质细胞建模的挑战与意义 | Elsharkasi, M. M. O. | N/A | Basal activation of astrocytic Nrf2 in neuronal culture media: challenges and implications for neuron-astrocyte modelling | |
| 光遗传学刺激背侧纹状体双向控制癫痫发作 | Hyder, S. K. | N/A | Optogenetic stimulation of dorsal striatum bidirectionally controls seizures | |
| 病毒介导的Oct4过表达与Notch信号通路的抑制协同作用，诱导哺乳动物Müller胶质细胞的神经发生能力。 | Le, N. | N/A | Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Muller glia. | |
| 结合颊部质量平面力学和解剖特征，可以改进海兔摄食行为的神经力学建模。 | Bennington, M. J. | N/A | Incorporating buccal mass planar mechanics and anatomical features improves neuromechanical modeling of Aplysia feeding behavior | |
| 淀粉样β调节小胶质细胞中硫胺素焦磷酸激酶-1表达的机制与后果 | Cheng, X. | N/A | The mechanism and consequences of amyloid-β modulating thiamine pyrophosphokinase-1 expression in microglia | |
| 侧化的小脑连接在小回声定位鲸和非回声定位鲸的听觉通路中有所区别。 | Flem, S. A. | N/A | Lateralized cerebellar connectivity differentiates auditory pathways in echolocating and non-echolocating whales | |
| 脊髓V1中间神经元的转录组图谱揭示了En1在运动输出特定元素中的作用 | Trevisan, A. J. | N/A | The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output | |
| 人类黄斑的形成涉及通过CYP26A1调控的两波视黄酸信号抑制，这调节了细胞周期退出和视锥细胞的特化。 | Harding, P. | N/A | Human macula formation involves two waves of retinoic acid signaling suppression via CYP26A1 regulating cell cycle exit and cone specification | |
| Mylpf 剂量与斑马鱼胚胎中快肌纤维的大小成比例。 | Adekeye, T. E. | N/A | Mylpf dosage is proportionate to fast-twitch myofibril size in the zebrafish embryo | |
| Gα亚单位Gq/11家族对于下颌骨的发育是必要且充分的。 | Kanai, S. M. | N/A | The Gq/11 family of Gα subunits is necessary and sufficient for lower jaw development | |
| 情感背景影响有蹄类动物的声纹特征 | Osiecka, A. N. | N/A | Emotional contexts influence vocal individuality in ungulates | |
| 单个神经元电生理记录和计算模型可以预测章鱼手臂的运动。 | Gedela, N. S. S. | N/A | Single unit electrophysiology recordings and computational modeling can predict octopus arm movement | |
| 黑色素瘤表面的陨石坑有助于肿瘤与免疫系统的相互作用，并在人类中显示出对检查点阻断的病理反应。 | Ludin, A. | N/A | Craters on the melanoma surface facilitate tumor-immune interactions and demonstrate pathologic response to checkpoint blockade in humans | |
| 使用整骨颅骶疗法手动触发自主神经系统反应的特异性研究 | Keller, M. | N/A | On the specificity of manual triggers of autonomic nervous system responses using osteopathic cranial manipulative medicine | |
| FUS通过液-液相分离介导的MEF2和ETV5招募来控制肌肉分化和结构 | Picchiarelli, G. | N/A | FUS controls muscle differentiation and structure through LLPS mediated recruitment of MEF2 and ETV5 | |
| 环境挑战期间集体社会行为的神经基础 | Raam, T. | N/A | Neural basis of collective social behavior during environmental challenge | |
| 对比认知、行为和生理反应：在反思室和VR头戴设备环境中，呼吸练习与自然主义刺激的效果 | Simonian, N. | N/A | Contrasting Cognitive, Behavioral, and Physiological Responses to Breathwork vs. Naturalistic Stimuli in Reflective Chamber and VR Headset Environments | |
| 人类神经类器官微生理系统展示了基本学习和记忆所需的构建模块 | Alam El Din, D.-M. | N/A | Human Neural Organoid Microphysiological Systems Show the Building Blocks Necessary for Basic Learning and Memory | |
| α-突触核蛋白预形成纤维诱导的聚集和多巴胺能细胞死亡在组织蛋白酶D过表达和ZKSCAN3敲除小鼠中的研究 | Mueller, T. | N/A | Alpha-synuclein preformed fibril-induced aggregation and dopaminergic cell death in cathepsin D overexpression and ZKSCAN3 knockout mice | |
| 光学神经影像工作室（OptiNiSt）：一个直观、可扩展、可扩展的光学神经影像数据分析框架 | Yamane, Y. | N/A | Optical Neuroimage Studio (OptiNiSt): intuitive, scalable, extendable framework for optical neuroimage data analysis | |
| 母鼠催产素神经元活动的灵活调节通过微型内窥镜技术揭示 | Yaguchi, K. | N/A | Flexible Adjustment of Oxytocin Neuron Activity in Mother Mice Revealed by Microendoscopy | |
| 网格细胞信息几何中的速度调制 | Ye, Z. | N/A | Speed modulations in grid cell information geometry | |
| 删除PTEN（而不是SOCS3或髓鞘抑制因子）显著增强了BRAF诱导的外周感觉轴突脊髓内再生。 | Kim, H. | N/A | Deleting PTEN, but not SOCS3 or myelin inhibitors, robustly boosts BRAF-elicited intraspinal regeneration of peripheral sensory axons | |
| 下丘脑内神经回路调控雄性小鼠交配射精后β-内啡肽的释放 | Zha, X. | N/A | Intra-hypothalamic circuit orchestrates β-endorphin release following coital ejaculation in male mice | |
| 在小胶质细胞炎症中的铜的作用 | Craciun, L. | N/A | Role of copper during microglial inflammation | |
| 黑质多巴胺能神经元动作电位形状及树突形态的产后发育 | Moubarak, E. M. | N/A | Postnatal Development Of Dendritic Morphology And Action Potential Shape In Rat Substantia Nigra Dopaminergic Neurons | |
| 眼压升高会损害视神经乳头中的轴突运输，导致神经退行性变，这是在一种新型Cre诱导的肌动蛋白青光眼小鼠模型中发现的。 | Kaipa, B. R. | N/A | Ocular hypertension impairs axonal transport in the optic nerve head leading to neurodegeneration in a novel Cre-inducible mouse model of myocilin glaucoma. | |
| 无监督对齐揭示了自然场景神经表征在个体和脑区之间的结构共性和差异 | Takeda, K. | N/A | Unsupervised alignment reveals structural commonalities and differences in neural representations of natural scenes across individuals and brain areas | |
| 通过ER-Hoxb8条件性永生化巨噬细胞替代小胶质细胞，为深入了解Aicardi-Goutieres综合征的神经病理学提供了新的视角。 | Nemec, K. M. | N/A | Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutieres Syndrome neuropathology | |
| 在经典条件反射过程中，小鼠纹状体纹状体成分中的多巴胺释放对奖励和厌恶结果的反应 | Yoshizawa, T. | N/A | Dopamine release in striatal striosome compartments in response to rewards and aversive outcomes during classical conditioning in mice | |
| 利用经皮脊髓刺激开发和评估一种非侵入式脑-脊接口 | Atkinson, C. J. | N/A | Development and evaluation of a non-invasive brain-spine interface using transcutaneous spinal cord stimulation | |
| 视觉词汇的大脑可塑性：小学教师可以在几周内推动的变化，与那些需要数年时间形成的变化相当。 | Wang, F. | N/A | Brain plasticity for visual words: Elementary school teachers can drive changes in weeks that rival those formed over years | |
| 在心脏形成过程中，心包膜作为一个独特的结构形成。 | Moran, H. R. | N/A | The pericardium forms as a distinct structure during heart formation | |
| 在心脏形成过程中，心包膜作为一个独立的结构形成。 | Moran, H. R. | N/A | The pericardium forms as a distinct structure during heart formation | |
| RFX3对于从多能干细胞衍生的人胰腺胰岛的发育和成熟至关重要。 | Memon, B. | N/A | RFX3 is essential for the development and maturation of human pancreatic islets derived from pluripotent stem cells | |
| RFX3对于从多能干细胞衍生的人胰腺胰岛的发育和成熟至关重要。 | Memon, B. | N/A | RFX3 is essential for the development and maturation of human pancreatic islets derived from pluripotent stem cells | |
| 中央纺锤体促进秀丽隐杆线虫锚定细胞的特化、外阴诱导及形态发生。 | Kato, T. | N/A | Centralspindlin promotes C. elegans anchor cell specification, vulva induction and morphogenesis | |
| Sox10Dom/+ 先天性巨结肠小鼠模型中的单细胞分析揭示了 Hoxa6 在肠神经元谱系分配中的作用 | Avila, J. A. | N/A | Single Cell Profiling in the Sox10Dom/+ Hirschsprung Mouse Implicates Hoxa6 in Enteric Neuron Lineage Allocation | |
| Sox10Dom/+ 先天性巨结肠小鼠中单一细胞分析揭示 Hoxa6 在肠神经元谱系分配中的作用 | Avila, J. A. | N/A | Single Cell Profiling in the Sox10Dom/+ Hirschsprung Mouse Implicates Hoxa6 in Enteric Neuron Lineage Allocation | |
| 在加利福尼亚中部城市环境中越冬的穴居猫头鹰（Athene cunicularia hypugaea）到达时间较晚，离开时间较早，偏好有遮蔽的微生境，能耐受雨水，并与多种捕食者竞争。 | Nicolaus, M. A. | N/A | Athene cunicularia hypugaea wintering in a central California urban setting arrive later, leave earlier, prefer sheltered micro-habitat, tolerate rain, and contend with diverse predators | |
| ECSFinder：从基因组序列中优化预测进化保守的RNA二级结构 | Gaonac'h-Lovejoy, V. A. | N/A | ECSFinder: Optimized prediction of evolutionarily conserved RNA secondary structures from genome sequences | |
| 一项关于外生菌根真菌松乳菇（Suillus luteus）本地种群和引入种群局部适应性的实验测试 | Allen, B. M. | N/A | An Experimental Test of Local Adaptation in Native and Introduced Populations of an Ectomycorrhizal Fungus, Suillus luteus | |
| 从头组装自私t超级基因揭示了有害的进化轨迹 | Runge, J.-N. | N/A | De novo assembly of the selfish t supergene reveals a deleterious evolutionary trajectory | |
| 植物根部的细胞间定向运输 | Jacquier, L. | N/A | Directional Cell-to-cell Transport in Plant Roots | |
| 欧洲凤尾鱼生态型形成由不同起源的结构变异和与南方谱系的遗传相互作用驱动 | Meyer, L. | N/A | Ecotype formation in the European anchovy fuelled by structural variants of different origins and genetic interactions with a southern lineage | |
| AyurPhenoClusters确定了罕见疾病的共同分子根源，并揭示了综合征条件下纤毛功能障碍。 | Joshi, A. | N/A | AyurPhenoClusters define common molecular roots for rare diseases and uncover ciliary dysfunctions in syndromic conditions | |
| DNFE：用于检测生物过程中临界点的有向网络流熵 | Peng, X. | N/A | DNFE: Directed-network flow entropy for detecting the tipping points during biological processes | |
| 白垩纪-古近纪大规模灭绝事件中的四足动物物种-面积关系 | Close, R. A. | N/A | Tetrapod species-area relationships across the Cretaceous-Paleogene mass extinction | |
| 综合转录组和代谢组分析揭示了中华蹄盖蕨鳞芽启动和发育的调控机制 | Yu, A. | N/A | Integrated Transcriptome and Metabolome Analyses Reveal the Mechanism Regulating Bulbil Initiation and Development in Cystopteris chinensis | |
| 灵长类新皮层中是否存在普遍的局部场电位功率的光谱层级模式？ | Mackey, C. A. | N/A | Is there a ubiquitous spectrolaminar motif of local field potential power across primate neocortex? | |
| 灵长类新皮层中是否存在普遍的局部场电位功率光谱层级模式？ | Mackey, C. A. | N/A | Is there a ubiquitous spectrolaminar motif of local field potential power across primate neocortex? | |
| β细胞外囊泡PD-L1作为1型糖尿病进展过程中CD8+ T细胞活性的新型调节因子及生物标志物 | Rao, C. | N/A | Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of Type 1 Diabetes | |
| 番茄斑萎病毒促进了非媒介性蜘蛛螨种类（Tetranychus urticae 和 Tetranychus evansi）在整个番茄植株上的活动。 | Gupta, V. | N/A | Tomato spotted wilt virus facilitates non-vector spider mite species (Tetranychus urticae and Tetranychus evansi) on whole tomato plants | |
| 不同农业混配助剂的生态毒性 | Bonn, D. | N/A | Eco-toxicity of different agricultural tank-mix adjuvants | |
| 一种世界性植物在其原产地和引入地的气候适应性 | Albano, L. J. | N/A | Adaptation to climate in the native and introduced ranges of a cosmopolitan plant | |
| 大多数野牛牛没有可检测到的野牛遗传祖先。 | Shapiro, B. | N/A | Most Beefalo cattle have no detectable bison genetic ancestry | |
| 线粒体超氧阴离子在肠道中发挥作用，以延长寿命 | Liontis, T. | N/A | Mitochondrial superoxide acts in the intestine to extend longevity | |
| 多重空间映射组织中的染色质特征、转录组和蛋白质 | Guo, P. | N/A | Multiplexed spatial mapping of chromatin features, transcriptome, and proteins in tissues | |
| 基因组分析表明，菌株VE202-06不存在万古霉素耐药性转移的风险。 | Watson, A. R. | N/A | Genomic Analyses Suggest No Risk of Vancomycin Resistance Transfer by Strain VE202-06 | |
| 猴子预测美国大选 | Jiang, Y. | N/A | Monkeys Predict US Elections | |
| 从有限数据预测蛋白质生物物理特性：通过NanoMelt研究纳米抗体热稳定性的案例 | Ramon, A. E. | N/A | Prediction of protein biophysical traits from limited data: a case study on nanobody thermostability through NanoMelt | |
| 从有限数据预测蛋白质生物物理特性：通过NanoMelt研究纳米抗体热稳定性的案例分析 | Ramon, A. E. | N/A | Prediction of protein biophysical traits from limited data: a case study on nanobody thermostability through NanoMelt | |
| 制造意识生成模型架构能够实现生物序列设计与合成达到千万亿次规模 | Weinstein, E. N. | N/A | Manufacturing-Aware Generative Model Architectures Enable Biological Sequence Design and Synthesis at Petascale | |
| 在植物中既充当隔离子又充当沉默子的小型DNA元件 | Jores, T. | N/A | Small DNA elements that act as both insulators and silencers in plants | |
| Th17细胞需要DNA修复传感器XPC来控制氧化性DNA损伤。 | Leite, J. A. | N/A | Th17 cells require the DNA repair sensor XPC to control oxidative DNA damage | |
| 抗原漂移过程中H3流感血凝素蛋白的结构和免疫学特性分析 | de Paiva Froes Rocha, R. | N/A | Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift | |
| 皮下脂肪组织中肥胖和2型糖尿病性别差异的转录组图谱 | Moldovan, R. A. | N/A | Transcriptomic landscape of sex differences in obesity and type 2 diabetes in subcutaneous adipose tissue | |
| 基于硫醇-烯点击反应的策略，用于定制可注射聚合物-纳米颗粒水凝胶的性质，以实现治疗性递送 | Bailey, S. J. | N/A | A thiol--ene click-based strategy to customize injectable polymer--nanoparticle hydrogel properties for therapeutic delivery | |
| 荧光pH敏感纳米传感器能够在高通量生物工艺制造中实现低体积的精确监测。 | Besenyei, G. C. | N/A | Fluorescent pH-sensitive nanosensors enable precise low-volume monitoring in high-throughput bioprocess manufacturing | |
| 无标记完整硫酸乙酰肝素寡糖的糖组学分析 | Maciej-Hulme, M. L. | N/A | Glycoinformatic profiling of label-free intact heparan sulfate oligosaccharides | |
| 通过原子级模拟探索生物分子凝聚物中的RNA不稳定机制 | Boccalini, M. | N/A | Exploring RNA destabilization mechanisms in biomolecular condensates through atomistic Simulations | |
| 在治疗错误折叠疾病的潜在纳米抗体中，构象稳定性和结合亲和力之间缺乏权衡 | Gomez-Mulas, A. | N/A | The lack of trade-off between conformational stability and binding affinity in a nanobody with therapeutic potential for a misfolding disease | |
| 利用人工神经网络实现分子动力学模拟轨迹的最优存储与便捷共享 | Wasim, A. | N/A | Employing Artificial Neural Networks for Optimal Storage and Facile Sharing of Molecular Dynamics Simulation Trajectories | |
| 炎症增加以及内质网应激和翻译减少区分了1型糖尿病前症状期胰腺胰岛与非糖尿病病例 | Swensen, A. C. | N/A | Increased Inflammation as well as Decreased Endoplasmic Reticulum Stress and Translation Differentiate Pancreatic Islets of Pre-symptomatic Stage 1 Type 1 Diabetes and Non-diabetic Cases | |
| 弓形虫慢性感染通过外周阿片受体信号传导降低内脏痛觉 | Audibert, A. | N/A | Toxoplasma gondii chronic infection decreases visceral nociception through peripheral opioid receptor signaling | |
| 含LOTUS结构域的蛋白PpLDCP3调控藓类植物小立碗藓的生殖细胞及散布单位的形成 | Kermanov, A. | N/A | The LOTUS-domain containing protein PpLDCP3 controls germline and dispersal unit formation in the moss Physcomitrium patens | |
| 基于光纤布拉格光栅的非破坏性根系表型分析系统，采用ResNet预测 | Binder, S. | N/A | Fiber Bragg grating based sensing system for non-destructive root phenotyping using ResNet prediction | |
| 早期分化被子植物中的基因组印记揭示了开花植物种子起始的古老机制 | Florez-Rueda, A. M. | N/A | Genomic imprinting in an early-diverging angiosperm reveals ancient mechanisms for seed initiation in flowering plants | |
| 肌醇多磷酸盐调控绿藻莱茵衣藻中的弹性机制，以适应极端营养条件。 | Bedera-Garcia, R. | N/A | Inositol polyphosphates regulate resilient mechanisms in the green alga Chlamydomonas reinhardtii to adapt to extreme nutrient conditions | |
| 植物对小麦瘿螨和小麦条锈病毒（WSMV）的反应：小麦对病毒耐受性的首次证据 | Pingault, L. | N/A | Plant responses to wheat curl mites and wheat streak mosaic virus (WSMV): first evidence of virus tolerance in wheat | |
| 双链RNA对埃及列当（Phelipanche aegyptiaca）种子萌发的非特异性效应 | Zainali, N. | N/A | Non-specific effect of double-stranded RNAs on Egyptian broomrape (Phelipanche aegyptiaca) seed germination | |
| 通过基于CRISPR/Cas9 RNP的植物体内基因编辑技术培育出的长保质期甜瓜 | Sasaki, K. | N/A | A long shelf-life melon created via CRISPR/Cas9 RNP-based in planta genome editing | |
| PGR5促进依赖能量的非光化学淬灭，以在波动光照下实现高效的C4光合作用。 | Woodford, R. | N/A | PGR5 promotes energy-dependent non-photochemical quenching to enable efficient C4 photosynthesis under fluctuating light | |
| 在拟南芥中，昼夜和发育时间尺度上的稳定且动态的基因表达模式 | Redmond, E. J. | N/A | Stable and dynamic gene expression patterns over diurnal and developmental timescales in Arabidopsis thaliana | |
| 通过基因组编辑调控下游保守非编码序列，优化TAWAWA1介导的水稻穗型结构 | Kuroha, T. | N/A | Fine-Tuning TAWAWA1-Mediated Panicle Architecture by Genome Editing of a Downstream Conserved Noncoding Sequence in Rice | |
| 遮荫通过SPL16/SPL23介导的细胞分裂素途径抑制杨树茎的形成层活动 | Wei, H. | N/A | Shade Inhibits Cambial Activity in Populus Stems by the SPL16/SPL23-Mediated Cytokinin Pathway | |
| 植物BCL-Domain同源物在SWI/SNF复合体的稳定性中发挥着保守的作用。 | Candela-Ferre, J. | N/A | Plant BCL-Domain Homologues play a conserved role in SWI/SNF complex stability | |
| 绿色藻类在适应有限二氧化碳环境时，二氧化碳浓缩机制与光呼吸的联合运作 | Dao, O. | N/A | Joint operation of the CO2 concentrating mechanism and photorespiration in green algae during acclimation to limiting CO2 | |
| 拟南芥AtGELP53通过寡糖介导的信号调节多糖乙酰化和防御反应 | Rastogi, L. | N/A | Arabidopsis AtGELP53 modulates polysaccharide acetylation and defense response through oligosaccharide-mediated signaling | |
| 在叶绿体中工程化Rubisco凝聚以调控植物光合作用 | Chen, T. | N/A | Engineering Rubisco Condensation in Chloroplasts to Manipulate Plant Photosynthesis | |
| 利用番茄相关细菌群落进行细菌性枯萎病的生物防治 | Tanaka, E. | N/A | Biocontrol of bacterial wilt disease using plant-associated bacterial communities in tomato | |
| M2巨噬细胞来源的外泌体通过抑制髓系细胞中的I型干扰素信号，逆转了饮食诱导心肌梗死小鼠的心脏功能下降。 | Ng, M. | N/A | M2 Macrophage Exosomes Reverse Cardiac Functional Decline in Mice with Diet-Induced Myocardial Infarction by Suppressing Type 1 Interferon Signaling in Myeloid Cells | |
| 多种平台稳定化的HIV-1 C亚型儿童包膜糖蛋白的设计与免疫原性研究 | Kumar, S. | N/A | Design and immunogenicity of an HIV-1 clade C pediatric envelope glycoprotein stabilized by multiple platforms | |
| 脑内AAV给药后诱导的针对衣壳的抗体以剂量依赖的方式限制了第二次给药 | Xu, Y.-G. | N/A | Antibodies against the capsid induced after intracranial AAV administration limits second administration in a dose dependent manner | |
| TREM2-p53信号轴活动中的遗传变异决定了氧气诱导的肺损伤 | Abe, Y. | N/A | Genetic variation in the activity of a TREM2-p53 signaling axis determines oxygen-inducedlung injury | |
| 古DNA揭示了大西洋蓝鳍金枪鱼的历史人口下降和遗传侵蚀 | Andrews, A. J. | N/A | Ancient DNA reveals historical demographic decline and genetic erosion in the Atlantic bluefin tuna | |
| 微气候传感器网络的工作流程：整合地理工具、统计数据和地方知识 | Klinges, D. H. | N/A | A workflow for microclimate sensor networks: integrating geographic tools, statistics, and local knowledge | |
| 剖析热带雨林中的蚯蚓多样性 | Goulpeau, A. | N/A | Dissecting earthworm diversity in tropical rainforests | |
| 软壳蛤（Mya arenaria）可传播癌症中的基因表达揭示了其在宿主感染和海水转移过程中的生存机制 | Hart, S. F. M. | N/A | Gene expression in soft-shell clam (Mya arenaria) transmissible cancer reveals survival mechanisms during host infection and seawater transfer | |
| 革兰氏阴性细菌中肽聚糖O-乙酰化的机制典型地体现了细菌MBOAT-SGNH酰基转移酶的作用方式。 | Anderson, A. C. | N/A | The mechanism of peptidoglycan O-acetylation in Gram-negative bacteria typifies bacterial MBOAT-SGNH acyltransferases | |
| LiverMap 管道用于人体肝脏的三维成像，揭示了肝硬化血管胆道结构的体积空间失调。 | Fabyan, W. B. | N/A | LiverMap pipeline for 3D imaging of human liver reveals volumetric spatial dysregulation of cirrhotic vasculobiliary architecture | |
| 通过可编程熵在平衡态下的分子计算 | Wang, B. | N/A | Molecular computation at equilibrium via programmable entropy | |
| 基于聚丙烯酰胺的抗菌共聚物，能够抵御典型抗药性机制，用于替代或挽救抗生素 | Williams, S. C. | N/A | Polyacrylamide-based Antimicrobial Copolymers Immune to Typical Resistance Mechanisms to Replace or Rescue Antibiotics | |
| QuickEd：基于边界与对齐的高性能精确序列比对 | Doblas, M. | N/A | QuickEd: High-performance exact sequence alignment based on bound-and-align | |
| 对大规模生物医学数据进行聚类，以建模疾病进展和抗微生物药物抗性进化中的动态积累过程 | Dauda, K. A. | N/A | Clustering large-scale biomedical data to model dynamic accumulation processes in disease progression and anti-microbial resistance evolution | |
| 全面绘制左旋多巴与帕金森病中铁代谢相互作用图谱 | Wang, J. | N/A | Comprehensive mapping of the Interaction of levodopa and iron metabolism in Parkinson's disease | |
| 利用大型语言模型提升基于生物标志物的肿瘤学试验匹配 | Al Khoury, N. | N/A | Enhancing Biomarker-Based Oncology Trial Matching Using Large Language Models | |
| 侧链化学编码的凝聚物固/液相变 | Chen, F. | N/A | Sidechain chemistry-encoded solid/liquid phase transitions of condensates | |
| 蠕动泵触发的淀粉样蛋白形成表明剪切应力是淀粉样蛋白成核的在体风险因素 | Goto, Y. | N/A | Peristaltic pump-triggered amyloid formation suggests shear stresses are in vivo risk factors of amyloid nucleation | |
| 负电荷，而非必需的磷酸化，是14-3-3蛋白识别配体所必需的 | Kamayirese, S. | N/A | Negative Charges, Not Necessary Phosphorylation, are Required for Ligand Recognition by 14-3-3 Proteins | |
| α-突触核蛋白高分辨率冷冻电镜结构测定 - 一种典型的淀粉样纤维 | Sanchez, J. C. | N/A | High-Resolution Cryo-EM Structure Determination of α-Synuclein - A Prototypical Amyloid Fibril | |
| 张力诱导的变构构象变化抑制解释了动力蛋白-1的协调步进 | Makino, T. | N/A | Tension-induced suppression of allosteric conformational changes explains coordinated stepping of kinesin-1 | |
| 驱动蛋白的两个马达结构域的动力学调控协调其在微管上的步进运动 | Niitani, Y. | N/A | Kinetic regulation of kinesin's two motor domains coordinates its stepping along microtubules | |
| 来自2型糖尿病患者的血浆外泌体可促进乳腺癌在患者来源的类器官中的侵袭性 | Ennis, C. S. | N/A | Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids | |
| 通过阻断FoxO3a的Neddylation，Epac1的药理学抑制对肺纤维化具有保护作用 | Jankowski, K. | N/A | Pharmacological Inhibition of Epac1 Protects against Pulmonary Fibrosis by Blocking FoxO3a Neddylation | |
| 一种无需灌胃的小鼠口服葡萄糖耐量测试精细方案的验证 | Pye, K. R. | N/A | Validation of a refined protocol for mouse oral glucose tolerance testing without gavage | |
| RFdiffusion在预测真菌病原体与谷类作物间蛋白质相互作用中的应用 | Haley, O. C. | N/A | Application of RFdiffusion to predict interspecies protein-protein interactions between fungal pathogens and cereal crops | |
| 细胞大小稳态的广义加法机制：对克隆增殖随机动力学的启示 | Nieto, C. | N/A | A Generalized Adder mechanism for Cell Size Homeostasis: Implications for Stochastic Dynamics of Clonal Proliferation | |
| 合并逻辑模型：在急性髓系白血病建模中的应用 | Li, L. X. | N/A | Merging logical models: An application in Acute Myeloid Leukemia modeling | |
| WEE1抑制剂延缓了雌激素受体阳性乳腺癌对CDK4/6抑制剂和抗雌激素治疗的耐药性 | He, W. | N/A | WEE1 inhibition delays resistance to CDK4/6 inhibitor and antiestrogen treatment in estrogen receptor-positive breast cancer | |
| 实验室条件下饲养智利小植绥螨的优化 | Nguyen, H. | N/A | Optimization of rearing Transeius montdorensis under laboratory conditions | |
| 第三型分泌系统诱导的液泡膜机械穿孔 | SWISTAK, L. | N/A | TYPE THREE SECRETION SYSTEM-INDUCED MECHANOPORATION OF VACUOLAR MEMBRANES | |
| T6SS DNase效应因子通过激活cGAS-STING-TNF轴引发核DNA损伤，从而触发细胞凋亡。 | Song, L. | N/A | A T6SS DNase effector induces nuclear DNA Damage to trigger apoptosis via activation of the cGAS-STING-TNF axis | |
| 不同生活方式在真菌界中的生物合成基因簇变异 | Allen, B. M. | N/A | Variation in Biosynthetic Gene Clusters Among Lifestyles Across Kingdom Fungi | |
| 常见膳食蛋白质成分的N-糖组谱的鉴定与比较 | Bolino, M. | N/A | Identification and comparison of N-glycome profiles from common dietary protein ingredients | |
| 高通量元分析抗菌肽以鉴定类别特异性治疗候选者：一种计算机方法 | Agrawal, P. | N/A | High Throughput Meta-analysis of Antimicrobial Peptides for Characterizing Class Specific Therapeutic Candidates: An in-silico Approach | |
| FLIMPA：一种适用于荧光寿命成像显微镜相量分析的多功能软件 | Kapsiani, S. | N/A | FLIMPA: A versatile software for Fluorescence Lifetime Imaging Microscopy Phasor Analysis | |
| 染色体不稳定性增加辐射敏感性 | Cosper, P. F. | N/A | Chromosomal instability increases radiation sensitivity | |
| 一种综合的超高效液相色谱-串联质谱（UHPLC-MS/MS）和提取方法，用于菠菜（Spinacia oleracea）中的黄酮类化合物 | Dzakovich, M. P. | N/A | A Comprehensive UHPLC-MS/MS and Extraction Method for Spinach (Spinacia oleracea) Flavonoids | |
| 铬还原细菌Bacillus tropicus的特性及分子机制研究 | Tuli, S. R. | N/A | Characterization and molecular insights of a chromium-reducing bacterium Bacillus tropicus | |
| 金黄色葡萄球菌噬菌体phi812的细胞附着与尾部收缩 | Binovsky, J. | N/A | Cell attachment and tail contraction of S. aureus phage phi812 | |
| 一种珊瑚肽对全球海洋病原体——溶珊瑚弧菌具有杀菌活性。 | Aoyama, K. | N/A | A coral peptide has bactericidal activity against a global marine pathogen, Vibrio coralliilyticus | |
| 多通道游戏中复式网络上的合作演化 | Basak, A. | N/A | Evolution of cooperation in multichannel games on multiplex networks | |
| 机器学习时代的整合建模：HADDOCK策略在CAPRI第47至55轮中的总结 | Reys, V. | N/A | Integrative modeling in the age of machine learning: a summary of HADDOCK strategies in CAPRI rounds 47-55 | |
| 新鲜人视网膜单细胞RNA测序图谱揭示了一种新型视锥细胞亚型及细胞多样性 | Yang, L. | N/A | Fresh Human Retinal scRNA-seq Atlas Reveals a Novel Cone Subtype and Cellular Diversity | |
| 固定剂灌注前后神经组织制备质量的比较研究 | Meyer-Dilhet, G. | N/A | Comparative study of pre- and post-mortem perfusion of fixative for the quality of neuronal tissue preparation | |
| 零回波时间成像实现了在小鼠中进行全脑活动图谱绘制，同时避免了腹侧信号的损失。 | Imamura, A. | N/A | Zero-echo time imaging achieves whole brain activity mapping without ventral signal loss in mice | |
| 果蝇中的神经元同步 | Fernandez-Chiappe, F. | N/A | Neuronal synchronization in Drosophila | |
| 色素分散因子对蚊子宿主搜寻持久性的昼夜调节影响每日叮咬模式 | Dong, L. | N/A | Circadian modulation of mosquito host-seeking persistence by Pigment-Dispersing Factor impacts daily biting patterns | |
| 生成一种可诱导的不稳定结构域Cre小鼠品系，以靶向疾病相关的小胶质细胞 | Henningfield, C. M. | N/A | Generation of an inducible destabilized-domain Cre mouse line to target disease associated microglia | |
| 氧化应激的隔离是必要的，但不足以得出姜黄素对多巴胺能神经的保护作用：来自ALSS果蝇帕金森病模型的见解 | Phom, L. | N/A | Sequestration of oxidative is necessary but not sufficient enough to conclude dopaminergic neuroprotective efficacy of curcumin: Insights from ALSS Drosophila Parkinson disease model | |
| 视觉引导伸手过程中参考框架间方向和距离的神经编码 | Harris Caceres, A. | N/A | Neural Encoding of Direction and Distance across Reference Frames in Visually Guided Reaching | |
| 基于SENP2的α-突触核蛋白N端截短在路易体病理传播中的作用 | Taguchi, K. | N/A | SENP2-based N-terminal truncation of α-synuclein in Lewy pathology propagation | |
| PARP1对ADP-核糖基化的全球重塑抑制了甲型流感病毒感染 | Zhang, Z. | N/A | Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection | |
| 微生物硫氧化菌和氨氧化菌在沿海海底生态状态中的关键作用 | Nilsen, T. | N/A | Key roles of microbial sulfur and ammonium oxidizers for the coastal seafloor ecological state | |
| 液滴测序揭示口腔生物膜外泌体中的毒力基因簇 | Takano, S. | N/A | Droplet Sequencing Reveals Virulence Gene Clusters in Oral Biofilm Extracellular Vesicles | |
| 通过lncRNA T-UCstem1依赖于DKK1调控WNT信号通路，实现对胚胎发育的非细胞自主性控制 | Coppola, A. | N/A | Non-cell-autonomous control of gastruloid development by the lncRNA T-UCstem1 through DKK1-dependent modulation of WNT signalling | |
| 从基因到模式：一个建模胚胎发育从转录调控中涌现的框架 | Garcia-Guillen, J. | N/A | From Genes to Patterns: A Framework for Modeling the Emergence of Embryonic Development from Transcriptional Regulation | |
| 利用基因组和线粒体数据揭示的濒危物种西伯利亚鼯鼠（Pteromys volans）的种群结构 | Ito dos Santos, F. | N/A | Population structure of the endangered Siberian flying squirrel (Pteromys volans) revealed by genomic and mitochondrial data | |
| 短期抗生素、诱导磁场与迁徙鸣禽的磁感应能力 | Sherf, G. | N/A | Short-term antibiotics, induced magnetic field, and magnetic sensitivity in a migratory songbird | |
| 一种快速、廉价、无培养、普适性的细菌鉴定系统，采用内部转录间隔区靶向引物：一项原理验证研究 | Asthana, V. | N/A | A rapid, inexpensive, culture-free, universal bacterial identification system using internal transcribed spacer targeting primers: a proof-of-principle study | |
| DuReS：一个用于去噪基于实验性串联质谱代谢组学数据的R包 | Banerjee, S. | N/A | DuReS: An R package for denoising experimental tandem mass spectrometry-based metabolomics data | |
| 晚发性阿尔茨海默病中内嗅皮层和海马基因的差异调控 | Biswas, M. | N/A | DIFFERENTIAL REGULATION OF GENES IN ENTORHINAL CORTEX AND HIPPOCAMPUS IN LATE ONSET AD | |
| CelloType：一种用于组织图像分割与分类的统一模型 | Pang, M. | N/A | CelloType: A Unified Model for Segmentation and Classification of Tissue Images | |
| 单细胞多模态组学整合方法的多任务基准测试 | Liu, C. | N/A | Multi-task benchmarking of single-cell multimodal omics integration methods | |
| 利用加权四联体分布增强全基因组数据物种树推断 | Hasan, N. B. | N/A | Leveraging weighted quartet distributions for enhanced species tree inference from genome-wide data | |
| 轨迹引导的降维方法用于多样本单细胞RNA测序数据，揭示了具有生物学意义的样本间异质性 | Zhuang, H. | N/A | Trajectory-guided dimensionality reduction for multi-sample single-cell RNA-seq data reveals biologically relevant sample-level heterogeneity | |
| STAG2-PAXIP1/PAGR1轴抑制肺肿瘤发生 | Ashkin, E. L. | N/A | A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis | |
| 分子磁共振成像检测锌分泌失调可早期发现胰腺导管腺癌病变及对KRASG12D抑制剂治疗的反应 | Jordan, V. C. | N/A | Molecular Magnetic Resonance Imaging of Dysregulated Zinc Secretion Detects Early Pancreatic Ductal Adenocarcinoma Lesions and Response to KRASG12D Inhibitor Treatment | |
| 黑皮质素-4受体拮抗剂TCMCB07缓解化疗引起的厌食和体重下降 | Zhu, X. | N/A | Melanocortin-4 receptor antagonist TCMCB07 alleviates chemotherapy-induced anorexia and weight loss | |
| 低强度电肌肉刺激对废用一周后大腿和小腿肌肉基因表达和表型的多向效应 | Borzykh, A. A. | N/A | Multidirectional effect of low-intensity electrical myostimulation on gene expression and phenotype in thigh and calf muscles after one week of disuse | |
| PMR4胼胝质合酶的缺失导致拟南芥和油菜对根肿病的抗性不依赖于水杨酸且具有广谱性 | Luo, B. | N/A | Loss of PMR4 callose synthase results in salicylic acid-independent and broad-spectrum resistance to clubroot in Arabidopsis and Brassica napus | |
| 密度依赖性彩色扫描电子显微镜（DDC-SEM）。在钙化组织研究中的应用及视觉影响。 | Tsolaki, E. | N/A | Density-Dependent Colour Scanning Electron Microscopy (DDC-SEM). Applications in the study of calcified tissues and visual impact. | |
| 体内酶选择系统的代谢生长耦合策略 | Alter, T. B. | N/A | Metabolic growth coupling strategies for in vivo enzyme selection systems | |
| 通过建模评估植物生长与防御之间的权衡关系，探讨初级代谢与次级代谢之间的相互作用 | Zrimec, J. | N/A | Evaluating plant growth-defence trade-offs by modelling the interaction between primary and secondary metabolism | |
| Cnes2b 调控宿主对隐球菌感染的抵抗力、炎症反应及组织损伤 | Angers, I. | N/A | Cnes2b Regulates Host Resistance, Inflammatory Responses and Tissue Damage Following Cryptococcus deneoformans Infection | |
| 缺氧介导的TLR7/9触发的人类浆细胞样树突状细胞（PDC）衍生的IFN-α反应的精细调控是通过细胞内和可溶性IFN调节因子的联合作用实现的。 | Lenkewitz, A. | N/A | Hypoxia-mediated fine-tuning of the TLR7/9-triggered human PDC-derived IFN-α response is mediated by combined cellular and soluble IFN-regulators | |
| 在斑马鱼神经杆内局部光遗传激活NMYII会导致长距离、不对称的力传播 | Crellin, H. A. | N/A | Local optogenetic NMYII activation within the zebrafish neural rod results in long-range, asymmetric force propagation | |
| 意外的是，一种多蚁后超级基因单倍型在蚁群超群体的Formica蚂蚁种群中缺失。 | Lagunas-Robles, G. | N/A | Unexpected absence of a multiple-queen supergene haplotype from supercolonial populations of Formica ants | |
| 性别、发育和营养依赖的北大西洋鲑鱼主要成熟年龄基因表达 | Asheim, E. R. | N/A | Sex-, development-, and nutrition-dependent expression of a major age-at-maturity gene in Atlantic salmon | |
| 番木瓜（番木瓜科）性别决定相关单核苷酸变异效应的预测 | Spelta, J. V. V. B. | N/A | PREDICTION OF SINGLE NUCLEOTIDE VARIANT EFFECTS RELATED TO SEX DETERMINATION IN Carica papaya (Caricaceae) | |
| 在存在胞嘧啶转换错误的情况下进行亚硫酸氢盐测序 | Ellis, T. J. | N/A | Bisulphite sequencing in the presence of cytosine-conversion errors | |
| 抗菌潜力与圣罗勒提取物合成银纳米粒子的表征 | Sulaiman, M. | N/A | Antimicrobial Potential and Characterization of Silver Nanoparticles Synthesized from Ocimum Sanctum Extract | |
| 滤波器组公共空间模式与基于包络的特征在多模态EEG-fTCD脑机接口中的应用 | Khalaf, A. | N/A | Filter bank common spatial pattern and envelope-based features in multimodal EEG-fTCD brain-computer interfaces | |
| 管道奥运会：针对DNA甲基化测序数据的计算工作流程的可连续基准测试，与实验金标准进行对比 | Lin, Y.-Y. | N/A | Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold-standard | |
| 低级别胶质瘤中IDH1状态和1p/19q共缺失分类的放射组学与连接组学方法比较研究 | Paradkar, R. V. | N/A | A Comparative Study of Radiomic and Connectomic Approaches to Classification of IDH1 Status and 1p/19q Co-deletion in Lower Grade Gliomas | |
| GWA-X：一个可扩展的GPU加速包，用于全基因组关联研究中的排列检验 | Agung, M. | N/A | GWA-X: An Extensible GPU Accelerated Package for Permutation Testing in Genome-Wide Association Studies | |
| 利用公开的数据非依赖性采集数据集对人类组织中基线蛋白质表达的综合视图 | Prakash, A. | N/A | Integrated View of Baseline Protein Expression in Human Tissues using public Data Independent Acquisition datasets | |
| Humatch - 快速、基因特异性抗体重链和轻链联合人源化 | Chinery, L. | N/A | Humatch - fast, gene-specific joint humanisation of antibody heavy and light chains | |
| 利用HetSIREN在实空间中对CryoEM构象状态进行异质性重构、精炼与解耦 | Herreros, D. | N/A | Real-space heterogeneous reconstruction, refinement, and disentanglement of CryoEM conformational states with HetSIREN | |
| SIRPalpha+ PD-L1+ 骨髓巨噬细胞通过调节T细胞功能促进AML生长 | Birch, F. | N/A | SIRPalpha+ PD-L1+ bone marrow macrophages aid AML growth by modulating T cell function | |
| 水通道蛋白-4的表达水平和定位异常与不同侵袭性胶质瘤的瘤周水肿呈负相关。 | Valente, O. | N/A | Aquaporin-4 expression levels and mis-localization are inversely linked to peritumoral edema in gliomas of varying aggressiveness | |
| DNA聚合酶θ介导的DNA修复是DNMT3A缺陷型白血病细胞的功能依赖性和治疗脆弱性 | Le, B. V. | N/A | DNA polymerase theta-mediated DNA repair is a functional dependency and therapeutic vulnerability in DNMT3A deficient leukemia cells | |
| 小鼠中PI3K持续激活和Pten缺失导致的睾丸性索间质肿瘤 | Dinevska, M. | N/A | Testicular sex cord stromal tumors in mice with constitutive activation of PI3K and loss of Pten | |
| TAU 20成功刺激心肌神经节丛，且未造成心脏损伤 | Li, S. | N/A | Successful stimulation of myocardial ganglionic plexuses by TAU 20 in the absence of cardiac damage | |
| 代谢建模揭示了IBD中宿主-微生物组代谢网络的多层次失调 | Taubenheim, J. | N/A | Metabolic modeling reveals a multi-level deregulation of host-microbiome metabolic networks in IBD | |
| 心脏-肿瘤模型中免疫检查点抑制剂治疗的最优控制 | van der Vegt, S. | N/A | Optimal control of immune checkpoint inhibitor therapy in a heart-tumour model | |
| 阐明早期肠道干细胞对细菌感染的反应 | Lebon, S. | N/A | Elucidating early intestinal stem cell response to bacterial infection | |
| 预测蛋白质靶向嵌合体的降解潜力 | Petrou, A. | N/A | Predicting Degradation Potential of Protein Targeting Chimeras | |
| BayesAge 2.0：一种用于预测转录组年龄的最大似然算法 | Pellegrini, M. | N/A | BayesAge 2.0: A Maximum Likelihood Algorithm To Predict Transcriptomic Age | |
| 变体评分在不同选择体制下的表现取决于变体与基因以及基因与疾病之间的关系。 | Finucane, H. K. | N/A | Variant scoring performance across selection regimes depends on variant-to-gene and gene-to-disease components | |
| 基于深度学习的基因扰动效应预测尚未超越简单的线性方法。 | Ahlmann-Eltze, C. | N/A | Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods | |
| 用于结构系统发育学的一般替代矩阵。 | Garg, S. G. | N/A | A general substitution matrix for structural phylogenetics. | |
| ArchMap：一个基于网络的平台，用于基于参考的单细胞数据集分析 | Lotfollahi, M. | N/A | ArchMap: A web-based platform for reference-based analysis of single-cell datasets | |
| 基准测试酶中运输通道研究中的粗粒度模拟方法 | Mandal, N. | N/A | Benchmarking coarse-grained simulation methods for investigation of transport tunnels in enzymes | |
| 细菌基因型预测的深度视频分析 | Dabouei, A. | N/A | Deep Video Analysis for Bacteria Genotype Prediction | |
| 嘌呤相互作用在生物矿物晶体形状决定中的作用 | Rothkegel, J. | N/A | The Role of Purine Interactions in Biogenic Crystal Shape Determination | |
| 肌肉纤维蛋白质组学揭示了性别和纤维类型特异性对阻力训练的适应 | Moesgaard, L. | N/A | Muscle fiber proteomics reveals sex- and fiber type-specific adaptations to resistance training | |
| 共享选择和遗传结构共同驱动了长期实验杂交种群中显著可重复的进化 | Owens, G. L. | N/A | Shared selection and genetic architecture drive strikingly repeatable evolution in long-term experimental hybrid populations | |
| 优化的CRISPR抑制和激活为斑马鱼系统生物学探索开辟了关键途径。 | Barrientos, N. B. | N/A | Optimized CRISPR inhibition and activation opens key avenues for systematic biological exploration in zebrafish. | |
| 染色质折叠模式定义了单等位基因中TAD结构的基本语法 | Messina, O. | N/A | Chromatin folding motifs define the basic grammar of TAD architecture in single alleles | |
| 人类4D核组结构与功能的综合视角 | The 4D Nucleome Consortium, | N/A | An integrated view of the structure and function of the human 4D nucleome | |
| 一个可访问的平台，用于量化载细胞水凝胶中的氧气扩散，并将其应用于海藻酸盐固定的胰腺β细胞 | Champion, K. | N/A | An accessible platform to quantify oxygen diffusion in cell-laden hydrogels and its application to alginate-immobilized pancreatic beta cells | |
| 稳健的CRISPR/dCas13 RNA阻断器能够特异性地干扰miRNA与其靶标的相互作用，并能拯救1型肌强直性营养不良病理 | Hanifi, M. | N/A | Robust CRISPR/dCas13 RNA blockers specifically perturb miRNA-target interactions and rescue type 1 myotonic dystrophy pathology | |
| 蛋白质pKa的精确快速预测：蛋白质语言模型揭示序列-pKa关系 | Xu, S. | N/A | Accurate and Rapid Prediction of Protein pKa: Protein Language Models Reveal the Sequence-pKa Relationship | |
| 一种战略性混合稳定聚合物，用于控制颗粒表面电荷，以增强粘液传输和细胞结合 | Stevens, C. A. | N/A | A Strategic Blend of Stabilizing Polymers to Control Particle Surface Charge for Enhanced Mucus Transport and Cell Binding | |
| 降低硫化氢生物利用度有助于保留射血分数的心脏代谢性心力衰竭 | Doiron, J. | N/A | Reduced Hydrogen Sulfide Bioavailability Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction | |
| 外周阿片受体拮抗作用可缓解芬太尼引起的心血管呼吸抑制，且无厌恶效应。 | Ruyle, B. | N/A | Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive effects | |
| SARS-CoV-2在皮肤上的存活及其从污染表面的转移 | Pitol Garcia, A. K. | N/A | SARS-CoV-2 Survival on Skin and its Transfer from Contaminated Surfaces | |
| Maf家族bZIP转录因子NRL与视网膜光感受器中的RNA结合蛋白及R环相互作用 | Corso Diaz, X. | N/A | Maf-family bZIP transcription factor NRL interacts with RNA-binding proteins and R-loops in retinal photoreceptors | |
| 利用计算分子网络工具对亨特利亚伞形叶甲醇和生物碱提取物中的次生代谢物进行研究 | Adedeji, R. A. | N/A | INVESTIGATION OF SECONDARY METABOLITES PRESENT IN METHANOLIC AND ALKALOIDAL EXTRACTS OF HUNTERIA UMBELLATA LEAVES USING COMPUTATIONAL MOLECULAR NETWORKING TOOL | |
| 唑类与非唑类药物激活白色念珠菌Pdr1调控通路的异同 | Conway, T. P. | N/A | Similarities and distinctions in the activation of the Candida glabrata Pdr1 regulatory pathway by azole and non-azole drugs | |
| 结构导向的工程改造：针对人类细胞靶向基因插入的I-F型CASTs | Lampe, G. D. | N/A | Structure-guided engineering of type I-F CASTs for targeted gene insertion in human cells | |
| 与导致人类疟疾的动物源病原体疟原虫（Plasmodium knowlesi）相关的病毒属于一个多样且未分类的病毒分类单元。 | Petrone, M. E. | N/A | A virus associated with the zoonotic pathogen Plasmodium knowlesi causing human malaria is a member of a diverse and unclassified viral taxon | |
| 在免疫细胞命运转换过程中，IRF8和FOS增强子对的协同和拮抗作用 | Klonizakis, A. | N/A | Synergistic and antagonistic activities of IRF8 and FOS enhancer pairs during an immune cell fate switch | |
| 亚塔霉素生物合成需要两种脱氧核糖核酸酶来实现毒素自我抗性。 | Dorival, J. | N/A | Yatakemycin biosynthesis requires two deoxyribonucleases for toxin self-resistance | |
| 分子水平解析电梯型金属转运蛋白中的底物转运机制 | Jafari, M. | N/A | Molecular insights into substrate translocation in an elevator-type metal transporter | |
| HDgraphiX：一种用于可视化氢氘交换质谱数据的基于网络的工具 | Vosper, K. R. | N/A | HDgraphiX: A web-based tool for visualization of hydrogen deuterium exchange mass spectrometry data | |
| 使用高分辨率质谱法进行小肠和粪便代谢组学分析的无靶向和半靶向代谢组学方法 | TRONEL, a. | N/A | Untargeted and Semi-Targeted Metabolomics Approach for Profiling Small Intestinal and Fecal Metabolome Using High-Resolution Mass Spectrometry | |
| 构象灵活性是设计广谱人诺如病毒蛋白酶抑制剂的关键因素。 | Pham, S. H. | N/A | Conformational flexibility is a critical factor in designing broad-spectrum human norovirus protease inhibitors | |
| 克莱兰免疫印迹揭示了意想不到的半胱氨酸氧化蛋白质形式 | Cobley, J. N. | N/A | Cleland Immunoblotting Unmasks Unexpected Cysteine Redox Proteoforms | |
| SCA5突变在β-III-血影蛋白的血影蛋白重复域中的分子后果 | Denha, S. | N/A | Molecular consequences of SCA5 mutations in the spectrin-repeat domains of beta-III-spectrin | |
| 人类核糖体通过延迟共翻译域对接来调节多结构域蛋白的生物合成。 | Pellowe, G. A. | N/A | The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking | |
| 微晶电子衍射（MicroED）结构揭示了氟替卡松糠酸酯和氟替卡松丙酸酯的新功能见解 | Lin, J. | N/A | MicroED Structures of Fluticasone Furoate and Fluticasone Propionate Provide New Insights to Their Function | |
| 人类半胱氨酸氧化还原蛋白质组型的计算分析揭示了新的见解 | Cobley, J. N. | N/A | Computational Analysis of Human Cysteine Redox Proteoforms Reveals Novel Insights | |
| 在ATP依赖性转位酶SMARCAL1、ZRANB3和HLTF的作用下，DNA复制叉反转过程中DNA损伤的链依赖性旁路机制 | Adolph, M. B. | N/A | Strand dependent bypass of DNA lesions during fork reversal by ATP-dependent translocases SMARCAL1, ZRANB3, and HLTF | |
| 高通量机器人分离人类iPS细胞克隆揭示了CRISPR-Cas9介导的相同遗传操作常导致同源纯合诱导 | Takahashi, G. | N/A | High-throughput robotic isolation of human iPS cell clones reveals frequent homozygous induction of identical genetic manipulations by CRISPR-Cas9 | |
| 高精度组装抛光与DeepPolisher | Mastoras, M. | N/A | Highly accurate assembly polishing with DeepPolisher | |
| 重新定义P环NTP酶早期进化中的功能连续性界限 | Demkiv, A. O. | N/A | Redefining the Limits of Functional Continuity in the Early Evolution of P-Loop NTPases | |
| 红细胞内恶性疟原虫寄生虫消耗血红蛋白的噪音：起源及可能的影响 | Perko, J. R. | N/A | Noisy hemoglobin consumption by erythrocytic Plasmodium falciparum parasites: origins and possible implications | |
| 对两种锰氧化酶的种群水平控制扩展了细菌锰生物矿化的生态位 | Gehin, G. | N/A | Population-level control of two manganese oxidases expands the niche for bacterial manganese biomineralization | |
| 胶质细胞源性神经营养因子家族受体α样蛋白（GFRAL）的表达仅限于尾部脑干。 | Hes, C. | N/A | GDNF family receptor alpha-like (GFRAL) expression is restricted to the caudal brainstem | |
| 一种基于草甘膦的除草剂在保留淡水细菌浮游生物群落内物种多样性的同时，选择性地促进了遗传变异。 | Derrick, E. | N/A | A glyphosate-based herbicide selects for genetic changes while retaining within-species diversity in a freshwater bacterioplankton community | |
| 在果蝇细胞中使用整合和抗CRISPR（IntAC）技术进行的高分辨率全基因组CRISPR敲除筛选 | Viswanatha, R. | N/A | Higher resolution pooled genome-wide CRISPR knockout screening in Drosophila cells using integration and anti-CRISPR (IntAC) | |
| 东非的“同一个健康”：产ESBL大肠杆菌的传播或独立抗菌素耐药基因在生态区间流动无障碍 | Musicha, P. | N/A | One Health in Eastern Africa: No barriers for ESBL producing E. coli transmission or independent antimicrobial resistance gene flow across ecological compartments | |
| 隐形荧光蛋白渲染：基因编码的4-氰色氨酸保留其结构并实现配体结合位点的检测 | Qianzhu, H. | N/A | Rendering Proteins Fluorescent Inconspicuously: Genetically Encoded 4-Cyanotryptophan Conserves Their Structure and Enables the Detection of Ligand Binding Sites | |
| 细胞内处理技术能够对低输入量的秀丽隐杆线虫进行快速且深入的蛋白质组分析。 | Elsayyid, M. | N/A | In-cell processing enables rapid and in-depth proteome analysis of low-input Caenorhabditis elegans | |
| # BioRxiv 2024-09-18 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 囊泡和非囊泡外泌体小RNA在植物相互作用细菌中指导基因沉默 | RAVET, A. | N/A | Vesicular and non-vesicular extracellular small RNAs direct gene silencing in a plant-interacting bacterium | |
| 解开皮质电路中多类中间神经元的稳定性和增益调制 | Bos, H. | N/A | Untangling stability and gain modulation in cortical circuits with multiple interneuron classes | |
| 自体受精脊椎动物中基因型和个体发育阶段的自体可育性变异 | Gresham, J. D. | N/A | Variation in self-compatibility among genotypes and across ontogeny in a self-fertilizing vertebrate | |
| 基于细胞外基质的简单代理建模框架 | Metzcar, J. | N/A | A simple framework for agent-based modeling with extracellular matrix | |
| 多组学图谱辅助发现选择性T细胞状态编程的转录因子 | Chung, H. K. | N/A | Multi-Omics Atlas-Assisted Discovery of Transcription Factors for Selective T Cell State Programming | |
| IL-13促进哮喘中感觉神经与交感神经的相互作用 | Crosson, T. | N/A | IL-13 promotes sensory-sympathetic neurons crosstalk in asthma | |
| 单一感觉的视觉和听觉对象在嗅觉皮层中得到处理，与气味关联无关。 | Thunell, E. | N/A | Unisensory visual and auditory objects are processed in olfactory cortex, independently of odor association | |
| DGRPool：一种利用协调的果蝇遗传参考面板表型数据研究复杂性状的网络工具 | Gardeux, V. | N/A | DGRPool: A web tool leveraging harmonized Drosophila Genetic Reference Panel phenotyping data for the study of complex traits | |
| 进化基因组学预测了高山森林关键树种对气候变化的适应性遗传和可塑性基因表达反应 | Long, Z. | N/A | Evolutionary genomics predicts adaptive genetic and plastic gene expression responses to climate change in a key alpine forest tree species | |
| 未来的抗生素在革兰氏阴性病原体中容易产生抗药性。 | Daruka, L. | N/A | Antibiotics of the future are prone to resistance in Gram-negative pathogens | |
| 主要人类诺如病毒的依赖RNA的RNA聚合酶会形成液-液相分离凝聚体，作为病毒复制工厂。 | Kaundal, S. | N/A | RNA-dependent RNA polymerase of predominant human norovirus forms liquid-liquid phase condensates as viral replication factories | |
| 膜脂质纳米域调节伤害感受器背根神经节神经元中的HCN起搏通道 | Handlin, L. J. | N/A | Membrane Lipid Nanodomains Modulate HCN Pacemaker Channels in Nociceptor DRG Neurons | |
| 行为上无关的特征匹配增加了神经和行为工作记忆的读出 | Karabay, A. | N/A | Behaviorally irrelevant feature matching increases neural and behavioral working memory readout | |
| HybriSeq：基于探针的无设备单细胞RNA分析 | Foyt, D. | N/A | HybriSeq: Probe-based Device-free Single-cell RNA Profiling | |
| 蜱虫的胞外囊泡在吸血过程中破坏表皮伤口愈合 | Marnin, L. | N/A | Tick extracellular vesicles undermine epidermal wound healing during hematophagy | |
| 三种RING蛋白的不同且相互依赖的功能调控哺乳动物减数分裂中的重组 | Ito, M. | N/A | Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis | |
| 人类RAD52的双环结构重塑复制叉，限制叉反转 | Honda, M. | N/A | A double-ring of human RAD52 remodels replication forks restricting fork reversal | |
| 图神经网络在人类大脑网络中结构-功能耦合的群体共性和个体特异性效应 | Chen, P. | N/A | Group-common and individual-specific effects of structure-function coupling in human brain networks with graph neural networks | |
| 骨骼肌卫星细胞利用肌腱生成基因Scleraxis指导再生 | Bai, Y. | N/A | Skeletal Muscle Satellite Cells Co-Opt the Tenogenic Gene Scleraxis to Instruct Regeneration | |
| 使用HaloTag技术在hiPSC衍生的单细胞和类器官中可视化PIEZO1的定位和活性 | Bertaccini, G. A. | N/A | Visualizing PIEZO1 Localization and Activity in hiPSC-Derived Single Cells and Organoids with HaloTag Technology | |
| 计算加速的P-糖蛋白抑制剂识别 | McCormick, L. A. | N/A | Computationally accelerated identification of P-glycoprotein inhibitors | |
| 利用生物电化学电池从甜菜汁中发电 | Shlosberg, Y. | N/A | Photoelectricity generation from beet juice in a bio-electrochemical cell | |
| 基于假设的可解释神经网络用于基因间相互作用 | Wang, S. | N/A | Hypothesis-driven interpretable neural network for interactions between genes | |
| 蛋白质-配体结合亲和力预测：是否需要三维结合构象？ | Wu, M.-H. | N/A | Protein-ligand binding affinity prediction: Is 3D binding pose needed? | |
| 内质网接触点促进含沙门氏菌液泡（SCV）的协调分裂 | Chopra, U. | N/A | Endoplasmic Reticulum contact sites facilitate the coordinated division of Salmonella-containing vacuole (SCV) | |
| 肿瘤微环境噪声诱导的极化：巨噬细胞癌症免疫治疗的主要挑战。 | Sierra, J. | N/A | Tumor microenvironment noise-induced polarization: the main challenge in macrophages' immunotherapy for cancer. | |
| 蛋白质组学和脂质组学血浆评估揭示加州海狮的软骨藻酸中毒生物标志物 | Solosky, A. M. | N/A | Proteomic and Lipidomic Plasma Evaluations Reveal Biomarkers for Domoic Acid Toxicosis in California Sea Lions | |
| 分子媒人：植原体效应因子SAP54通过靶向MADS-box因子SVP，通过调节叶片对雄性存在的反应，增强了对多产雌性媒介的吸引力 | Orlovskis, Z. | N/A | Molecular Matchmakers: Phytoplasma Effector SAP54 Targets MADS-Box Factor SVP to Enhance Attraction of Fecund Female Vectors by Modulating Leaf Responses to Male Presence | |
| 使用Sentence-BERT从预测数据库中提炼疾病相关的蛋白质水平微RNA靶标相互作用 | Chen, B. | N/A | Refining Protein-Level MicroRNA Target Interactions in Disease from Prediction Databases Using Sentence-BERT | |
| 利用无人机系统和计算机视觉对涉禽进行近实时监测 | White, E. P. | N/A | Near real-time monitoring of wading birds using uncrewed aircraft systems and computer vision | |
| 探索选择的多元信心 | Solopchuk, O. | N/A | Multifaceted confidence in exploratory choice | |
| 恐惧记忆合作与竞争的时间规则 | Madeira, N. | N/A | Temporal rules of fear memory cooperation and competition | |
| 同型相分离的直接和间接盐效应 | MacAinsh, M. | N/A | Direct and Indirect Salt Effects on Homotypic Phase Separation | |
| 基于模型的浮萍生物发光报告基因活动昼夜节律生成分析 | Horikawa, Y. | N/A | Model-based analysis of the circadian rhythm generation of bioluminescence reporter activity in duckweed | |
| 按蚊种群空间结构在冈比亚按蚊复合体中的变异 | McCann, R. S. | N/A | Variation in spatial population structure in the Anopheles gambiae species complex | |
| 一年内皮层厚度、表面积和脑体积的个体内部稳定性 | Wang, M.-Y. | N/A | The within-subject stability of cortical thickness, surface area, and brain volumes across one year | |
| 在许多研究中，可避免的假PSMC种群规模峰值时有发生。 | Hilgers, L. | N/A | Avoidable false PSMC population size peaks occur across numerous studies | |
| 基因型与环境相互作用在基因调控中的作用，揭示了模式草本植物短柄草（Brachypodium distachyon）对土壤干燥的响应机制。 | Yun, J. | N/A | Genotype by environment interactions in gene regulation underlie the response to soil drying in the model grass Brachypodium distachyon | |
| 突变扩展规律揭示，通过基因扩增实现加速进化需要空间结构化的种群增长。 | Komarova, N. | N/A | Mutant scaling laws reveal that accelerated evolution via gene amplification requires spatially structured population growth | |
| 免疫检查点抑制后的细胞动力学 | Lin, Z. | N/A | Cellular Dynamics Upon Immune Checkpoint Inhibition | |
| 从单一序列到进化轨迹：蛋白质语言模型捕捉SARS-CoV-2蛋白质序列的进化潜力 | Lamb, K. D. | N/A | From a single sequence to evolutionary trajectories: protein language models capture the evolutionary potential of SARS-CoV-2 protein sequences | |
| ANASFV：一种用于非洲猪瘟病毒全基因组测序、组装和评估的工作流程 | Li, K. | N/A | ANASFV: a workflow for ASFV whole genome sequencing, assembly, and evaluation | |
| bam转录本的失稳终止了果蝇雌性生殖系分化的有丝分裂阶段 | Samuels, T. J. | N/A | Destabilisation of bam transcripts terminates the mitotic phase of Drosophila female germline differentiation | |
| 使用全原子模拟对错误建模的冷冻电镜RNA结构进行集合细化 | Posani, E. | N/A | Ensemble Refinement of mismodeled cryo-EM RNA Structures Using All-Atom Simulations | |
| 撤回：木薯褐条病致病病毒间的种间重组 | Astacio-Berrios, K. | N/A | WITHDRAWN: Interspecies recombination between cassava brown streak disease-causing viruses | |
| 蓝藻中m4C DNA甲基化对四吡咯生物合成的表观遗传调控 | Schmidt, N. | N/A | Epigenetic control of tetrapyrrole biosynthesis by m4C DNA methylation in a cyanobacterium | |
| 分离的基底神经节输出通路与基因上不同的神经元亚类相对应。 | Mendelsohn, A. | N/A | Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses | |
| 安第斯叶耳鼠（Phyllotis）的物种界限与杂交现象 | Quiroga-Carmona, M. | N/A | Species limits and hybridization in Andean leaf-eared mice (Phyllotis) | |
| 泛基因组学用于理解Pectobacterium属中的原噬菌体动力学以及P. brasiliense辐射谱系的演化 | Pardeshi, L. A. | N/A | Pangenomics to understand prophage dynamics in the Pectobacterium genus and the radiating lineages of P. brasiliense | |
| 丝虫精子发生过程中重组、X染色体失活及着丝粒蛋白的动态变化 | Toubiana, W. | N/A | Dynamics of recombination, X inactivation and centromere proteins during stick insect spermatogenesis | |
| 梅克尔细胞癌衍生的巨噬细胞移动抑制因子（MIF）可能促进慢性淋巴细胞白血病的持续存在。 | Alencar, G. F. | N/A | Merkel cell carcinoma-derived macrophage migration inhibitory factor (MIF) may promote persistence of Chronic Lymphocytic Leukemia | |
| 在海马体的循环网络模型中，条形码活动能够实现高效的记忆绑定。 | Fang, C. | N/A | Barcode activity in a recurrent network model of the hippocampus enables efficient memory binding | |
| Mouse-Geneformer：一种用于小鼠单细胞转录组的深度学习模型及其跨物种应用 | Ito, K. | N/A | Mouse-Geneformer: A Deep Learning Model for Mouse Single-Cell Transcriptome and Its Cross-Species Utility | |
| 物体非刚性的各向异性：皮层各向异性的高层次感知结果 | Maruya, A. | N/A | Anisotropy of object non-rigidity: High-level perceptual consequences of cortical anisotropy | |
| LncRNA TAAL是糖尿病视网膜病变中通过Tie1介导的血管功能的调节因子 | Ranjan, G. | N/A | LncRNA TAAL is a Modulator of Tie1-Mediated Vascular Function in Diabetic Retinopathy | |
| MEK1/2激酶与c-Myc:MAX协同作用，防止人类多能干细胞中TERT受到多梳蛋白的抑制。 | Kotian, S. T. | N/A | MEK1/2 kinases cooperate with c-Myc:MAX to prevent polycomb repression of TERT in human pluripotent stem cells | |
| MAPK/ERK信号通路在胶质瘤中调控干扰素反应、T细胞招募，增强肿瘤-小胶质细胞间的相互作用，并推动免疫检查点阻断疗法的疗效。 | Kim, K.-S. | N/A | MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, enhances tumor-microglia crosstalk, and drives immune checkpoint blockade efficacy. | |
| MAPK/ERK信号通路在胶质瘤中调节干扰素反应、T细胞招募，增强肿瘤与小胶质细胞的相互作用，并推动免疫检查点阻断疗法的疗效。 | Kim, K.-S. | N/A | MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, enhances tumor-microglia crosstalk, and drives immune checkpoint blockade efficacy. | |
| 蜱虫中单一的 ANP32 祖先位点创造了多种蛋白质变体，这些变体均支持 Thogoto 病毒聚合酶的功能。 | Zhang, Z. | N/A | A single ancestral ANP32 locus in ticks creates multiple protein variants that all support the Thogoto virus polymerase | |
| 海马体中人口活动的稀疏性在三突触回路和背腹轴上是任务不变的。 | Lee, J. Q. | N/A | Sparsity of population activity in the hippocampus is task-invariant across the trisynaptic circuit and dorsoventral axis | |
| 从前馈到反馈节奏的表征转变，在自然视觉中标志着现象学整合的指标。 | Chen, L. | N/A | Representational shifts from feedforward to feedback rhythms index phenomenological integration in naturalistic vision | |
| 面部表情与颜色在调节ERP P3中的相互作用 | Hasegawa, Y. | N/A | Interaction between facial expression and color in modulating ERP P3 | |
| 一个涵盖5000年历史的考古牙结石数据集，用于古代人类口腔微生物组研究 | Standeven, F. J. | N/A | An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research | |
| 一种慢性小鼠肺部鲍曼不动杆菌感染模型，可用于研究晚期毒力因子、长期抗生素治疗和多微生物感染。 | Jackson-Litteken, C. D. | N/A | A chronic murine model of pulmonary Acinetobacter baumannii infection enabling the investigation of late virulence factors, long-term antibiotic treatments, and polymicrobial infections | |
| 无细胞人乳头瘤病毒DNA在转移性或复发性宫颈癌中的监测：临床意义与治疗启示 | Yin, Z. | N/A | Monitoring of Cell-free Human Papillomavirus DNA in Metastatic or Recurrent Cervical Cancer: Clinical Significance and Treatment Implications | |
| 肢体上的学习：一个旨在吸引高中生参与骨科的推广模块 | Panebianco, C. J. | N/A | Learning on a Limb: An outreach module to engage high school students in orthopaedics | |
| 药物难治性癫痫中的性别特异性补体和细胞因子失衡：免疫脆弱性的生物标志物 | Pinzon-Hoyos, N. | N/A | Sex-Specific Complement and Cytokine Imbalances in Drug-Resistant Epilepsy: Biomarkers of Immune Vulnerability | |
| 非平衡涨落-耗散定理为阿尔茨海默病研究铺平道路 | Patow, G. A. | N/A | Off-Equilibrium Fluctuation-Dissipation Theorem Paves the Way in Alzheimer's Disease Research | |
| 阿尔茨海默病中默认模式网络功能障碍和认知衰退的神经生理学特征。 | Ozdemir, R. A. | N/A | Neurophysiological signatures of default mode network dysfunction and cognitive decline in Alzheimer disease. | |
| 相机类型、高度及图像增强对浑浊海洋环境中摄影测量成功率的影响。 | Savill, K. L. | N/A | Influence of camera type, height and image enhancement on photogrammetry success in turbid marine environments. | |
| 系统性CD8+ T细胞效应器特征预测肺癌免疫治疗预后 | Sim, H. | N/A | Systemic CD8+ T cell effector signature predicts prognosis of lung cancer immunotherapy | |
| 支气管和鼻腔粘液的比较表征揭示了流感A病毒抑制的关键决定因素 | Pohl, M. O. | N/A | Comparative Characterization of Bronchial and Nasal Mucus Reveals Key Determinants of Influenza A Virus Inhibition | |
| Medin诱导人脑血管平滑肌细胞的促炎激活 | Karamanova, N. | N/A | Medin Induces Pro-Inflammatory Activation of Human Brain Vascular Smooth Muscle Cells | |
| CRISPR/Cas9诱导的断裂不足以打破番茄（Solanum lycopersicum）中烟草花叶病毒（ToMV）位点周围的连锁拖曳。 | Grubben, J. | N/A | CRISPR/Cas9-induced breaks are insufficient to break linkage drag surrounding the ToMV locus of Solanum lycopersicum | |
| 豆科（Legume）安麦斯米亚族（Amherstieae）中的生态位保守性：来自热带柏林尼亚支系（Berlinia）和布劳恩尼亚支系（Brownea）的启示 | Romero, I. C. | N/A | Niche conservatism in the Legume Amherstieae tribe: Insights from the tropical Berlinia and Brownea clades | |
| 非重组种群中选择性清除过程中的遗传多样性 | Kaushik, S. | N/A | Genetic diversity during selective sweeps in non-recombining populations | |
| 一种用于治疗性RNA质量控制的纳米孔测序碱基识别的迭代优化方法 | Wang, Z. | N/A | An Iterative Approach to Polish the Nanopore Sequencing Basecalling for Therapeutic RNA Quality Control | |
| 按蚊中分子Toll通路的多样性 | Rhodes, V. L. | N/A | The molecular Toll pathway repertoire in anopheline mosquitoes | |
| 一种红色荧光Lifeact标记物用于研究足细胞中的肌动蛋白形态 | Wiesner, E. | N/A | A Red Fluorescent Lifeact Marker to Study Actin Morphology in Podocytes | |
| 选择常染色体显性DFNA11耳聋突变激活上皮细胞中的Myo7A | Acharya, P. | N/A | Select autosomal dominant DFNA11 deafness mutations activate Myo7A in epithelial cells | |
| 靶向与帕金森病相关的LRRK2的II型激酶抑制剂 | Raig, N. D. | N/A | Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2 | |
| Seipin调控了Caveolin-1的运输以及细胞器间的交流 | Carpentier, M. | N/A | Seipin Regulates Caveolin-1 Trafficking and Organelle Crosstalk | |
| 甲醛在用于哺乳动物细胞培养时对信号通路的影响 | Ostmann, K. | N/A | Influence of formaldehyde on signaling pathways when used in mammalian cell culture | |
| A型和B型核纤层蛋白的详细共定位分析：使用超分辨率STED显微镜和去卷积的工作流程 | Stiekema, M. | N/A | Detailed Colocalization Analysis of A- and B-type Nuclear Lamins: a Workflow Using Super-Resolution STED Microscopy and Deconvolution | |
| 溶酶体膜蛋白LAMP2B介导微脂质吞噬作用，以针对与肥胖相关疾病 | Sakai, R. | N/A | The lysosomal membrane protein LAMP2B mediates microlipophagy to target obesity-related disorders | |
| 通过等离子体超表面实现活细胞的中红外化学成像 | Huang, S. H. | N/A | Mid-infrared chemical imaging of living cells enabled by plasmonic metasurfaces | |
| 降低氧化应激改善了基于聚合物的体外人类造血干细胞和祖细胞培养及基因编辑 | Bozhilov, Y. | N/A | Reducing oxidative stress improves ex vivo polymer-based human haematopoietic stem and progenitor cell culture and gene editing | |
| 后负荷诱导的脂肪酸氧化减少独立于葡萄糖利用增加而发展 | Piristine, H. | N/A | Afterload-induced Decreases in Fatty Acid Oxidation Develop Independently of Increased Glucose Utilization | |
| 解锁精准：角膜细胞面积分析如何革新移植后干细胞监测 | Parkinson, P. | N/A | Unlocking precision: How corneal cell area analysis revolutionises post-transplant stem cell monitoring | |
| 体外评估挪威云杉（Picea abies）树脂提取物在口腔护理应用中的抗炎、抗牙菌斑功效及生物相容性 | Yamileva, K. | N/A | In Vitro Evaluation of Anti-Inflammatory, Anti-Plaque Efficacy, and Biocompatibility of Norway Spruce (Picea abies) Resin Extract for Oral Care Applications | |
| 社会注意力取决于精确度的调节 | Gao, W. | N/A | Precision-dependent modulation of social attention | |
| 采用SynthSeg框架和规范建模方法进行多发性硬化萎缩的纵向表征 | Gordaliza, P. M. | N/A | Towards Longitudinal Characterization of Multiple Sclerosis Atrophy Employing SynthSeg Framework and Normative Modeling | |
| CRISPR筛选用于rAAV生产的基因，揭示了与感染相关的基因 | O'Driscoll, E. | N/A | CRISPR screen for rAAV production implicates genes associated with infection | |
| 每月对大型藻类的调查揭示了城市潮间带中一个多样且动态的生物群落。 | Schenk, S. | N/A | Monthly macroalgal surveys reveal a diverse and dynamic community in an urban intertidal zone | |
| 针对未被关注的目标：揭示根系分泌物的化学复杂性 | Moeller, K. | N/A | Targeting the untargeted: Uncovering the chemical complexity of root exudates | |
| 在孟德尔群体中，利他主义全同胞之间的生存成本分担 | Garay, J. | N/A | Survival cost sharing among altruistic full siblings in Mendelian population | |
| 在大规模临床肺癌样本中筛选和鉴定基因表达，揭示了EZH2和SOX2的主要作用。 | Niharika, | N/A | Screening and identification of gene expression in large cohorts of clinical lung cancer samples unveils the major involvement of EZH2 and SOX2 | |
| 结核菌细胞壁阿拉伯聚糖末端阿拉伯糖基化的结构洞察 | Liu, Y. | N/A | Structural insights into terminal arabinosylation biosynthesis of the mycobacterial cell wall arabinan | |
| 通过甘露糖基转移酶PimE研究分枝杆菌糖脂生物合成的机制 | Liu, Y. | N/A | Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE | |
| 一种针对大蜡螟蛾（Galleria mellonella）的显微注射技术方案 | Pearce, J. C. | N/A | A microinjection protocol for the greater waxworm moth, Galleria mellonella | |
| 可溶性细胞间通讯的工程受体 | Piraner, D. I. | N/A | Engineered Receptors for Soluble Cell-to-Cell Communication | |
| 不同硬度聚丙烯酰胺（PAAm）水凝胶的合成及其在大批量细胞培养应用中的力学表征 | Cresens, C. | N/A | Synthesis and mechanical characterization of polyacrylamide (PAAm) hydrogels with different stiffnesses for large-batch cell culture applications | |
| UDG识别出双链DNA中翻转出来的尿嘧啶碱基的“那一刻” | Saravanan, V. | N/A | The "very moment" when UDG recognizes aflipped-out uracil base in dsDNA | |
| 基于网络的抗癌药物组合疗效和不良反应潜力评估，以优先排序 | Ghosh, A. | N/A | Network-based estimation of therapeutic efficacy and adverse reaction potential for prioritisation of anti-cancer drug combinations | |
| 一种综合方法，用于提取经历液-液相分离的球状蛋白质的旋转动力学 | Gendreizig, D. | N/A | A combined approach to extract rotational dynamics of globular proteins undergoing liquid-liquid phase separation | |
| 综合多组学方法揭示ZMAT3和p21在p53肿瘤抑制网络中作为保守枢纽的作用 | Boutelle, A. M. | N/A | Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network | |
| 鉴定针对FGFR2融合驱动的胆管癌的高效双特异性抗体。 | Chaturantabut, S. | N/A | Identification of potent biparatopic antibodies targeting FGFR2 fusion driven cholangiocarcinoma. | |
| 通过单细胞空间分析鉴定人肺组织中结核菌感染的SPP1阳性巨噬细胞 | Katano, H. | N/A | Identification of SPP1-positive macrophages by single-cell spatial analysis in human lung tissues with mycobacterial infection | |
| 内皮miR-34a缺失虽导致内皮功能障碍，但能防止动脉瘤的发展。 | Grochot-Przeczek, A. | N/A | Endothelial miR-34a deletion guards against aneurysm development despite endothelial dysfunction | |
| 胆固醇与VCAM-1结合促进血管炎症 | Kennelly, J. P. | N/A | Cholesterol binding to VCAM-1 promotes vascular inflammation | |
| 灵长类主要组织相容性复合体：基因家族进化的一个典型例证 | Fortier, A. L. | N/A | The Primate Major Histocompatibility Complex: An Illustrative Example of Gene Family Evolution | |
| 果蝇母体效应基因异常卵细胞（ao）并不抑制组蛋白基因的表达。 | Takenaka, R. | N/A | The Drosophila maternal-effect gene abnormal oocyte (ao) does not repress histone gene expression | |
| 一个驱动不可简化的分子复合物反复进化的调控模块。 | Tikanova, P. | N/A | A regulatory module driving the recurrent evolution of irreducible molecular complexes. | |
| 犬基因组组装中核线粒体插入的特征分析 | Schall, P. Z. | N/A | Characterization of nuclear mitochondrial insertions in canine genome assemblies | |
| 从单体到寡聚体：先天免疫信号传导中受体触发的MyD88组装的结构机制 | Kasai, K. | N/A | From Monomers to Oligomers: Structural Mechanism of Receptor-Triggered MyD88 Assembly in Innate Immune Signaling | |
| 突变型p53错误折叠与聚集先于高级别浆液性卵巢癌的转化 | Sartini, S. | N/A | Mutant p53 Misfolding and Aggregation Precedes Transformation into High-Grade Serous Ovarian Carcinoma | |
| 体外小鼠精准切割肿瘤切片用于肝细胞癌建模；一种适用于大规模药物筛选的3R解决方案 | Collins, A. L. | N/A | Ex-vivo mouse precision cut tumour slices for modelling hepatocellular carcinoma; A 3Rs solution for at-scale drug screening | |
| 体外和体内评估海藻对伤口愈合的作用 | Wang, C.-H. | N/A | In vitro and in vivo evaluation of Ulva lactuca for wound healing | |
| 在杂交小麦种子生产中，污点持久性并不是一个主要的限制因素。 | Millan-Blanquez, M. | N/A | Stigma longevity is not a major limiting factor in hybrid wheat seed production | |
| 评估HIV-1包膜构象可塑性背景下的广谱中和抗体效能 | Foulkes, C. | N/A | Assessing bnAb potency in the context of HIV-1 Envelope conformational plasticity | |
| 研究法洛四联症右心室血流动力学：一项计算研究 | Renzi, F. | N/A | Investigating the right heart hemodynamics in the Tetralogy of Fallot: a computational study | |
| PANOMIQ：一种统一的全基因组、外显子和微生物组数据分析方法 | Srivastava, S. | N/A | PANOMIQ: A Unified Approach to Whole-Genome, Exome, and Microbiome Data Analysis | |
| RCoxNet：结合随机游走重启与突变及临床数据的癌症生存预测深度学习框架 | Kumari, S. | N/A | RCoxNet: deep learning framework for enhanced cancer survival prediction integrating random walk with restart with mutation and clinical data | |
| 协同药物发现中的主动学习指南 | Wang, S. | N/A | A Guide for Active Learning in Synergistic Drug Discovery | |
| FunCoup 6：通过引入有向链接和提升用户体验，推进跨物种功能关联网络的发展 | Buzzao, D. | N/A | FunCoup 6: advancing functional association networks across species with directed links and improved user experience | |
| 环境和未减数配子的遗传结构如何影响同源多倍体的形成 | Cheng, Y. | N/A | How environment and genetic architecture of unreduced gametes shape the establishment of autopolyploids | |
| 动物遗传变异致病性客观评估的变异分类指南 | Boeykens, F. | N/A | Variant classification guidelines for animals to objectively evaluate genetic variant pathogenicity | |
| 侧前额叶皮层控制工作记忆与行动之间的相互作用。 | Kiyonaga, A. | N/A | Lateral prefrontal cortex controls interplay between working memory and actions | |
| 急性病毒感染加速肌萎缩侧索硬化症小鼠模型中的神经退行性变 | Marzok, A. | N/A | Acute Viral Infection Accelerates Neurodegeneration in a Mouse Model of ALS | |
| 蛋白质组学和N-糖基组学比较：合成与牛乳清蛋白及其对人类肠道微生物群的影响 | Bolino, M. | N/A | Proteomic and N-glycomic comparison of synthetic and bovine whey proteins and their effect on human gut microbiomes | |
| 分子活性调节湖泊沉积物中溶解有机质的组成和组装 | Wen, S. | N/A | Molecular activity mediates the composition and assembly of dissolved organic matter in lake sediments | |
| 胞质CRISPR RNA用于RNA靶向CRISPR-Cas系统 | Kwon, S. C. | N/A | Cytosolic CRISPR RNA for RNA-targeting CRISPR-Cas systems | |
| 基于转录程序的MET外显子14跳跃调控网络解析 | Truong, M.-J. | N/A | Transcriptional-program-based deciphering of the MET exon 14 skipping regulation network | |
| Cas9AEY（Cas9辅助的非特异性大肠杆菌酵母载体同源重组组装）构建大型DNA的方法。 | ma, x. | N/A | Cas9AEY (Cas9-facilitated Homologous Recombination Assembly of non-specific Escherichia coli yeast vector) method of constructing large-sized DNA. | |
| 肠道定居调节性T细胞（GTregs）的稳态平衡在维持绝经后骨质疏松症条件下的骨骼健康中起着关键作用。 | Bhardwaj, A. | N/A | Homeostatic balance of Gut-resident Tregs (GTregs) plays a pivotal role in maintaining bone health under post-menopausal osteoporotic conditions | |
| IL-27中和以调节肿瘤微环境并提高免疫检查点免疫治疗效果 | Papargyris, L. | N/A | IL-27 neutralization to modulate the tumor microenvironment and increase immune checkpoint immunotherapy efficacy | |
| NMI通过激活NF-kappaB通路诱导趋化因子释放并招募中性粒细胞。 | Chen, Z. | N/A | NMI induces chemokine release and recruits neutrophils through the activation of NF-kappaB pathway | |
| 疟原虫物种的DNA复制动力学与基因组组成相关 | Totanes, F. I. G. | N/A | DNA replication dynamics are associated with genome composition in Plasmodium species | |
| 一种从古代口腔微生物组创建宏基因组组装基因组的高效流程 | Standeven, F. J. | N/A | An efficient pipeline for creating metagenomic-assembled genomes from ancient oral microbiomes | |
| 一种针对泛素调节的功能性筛选鉴定出由铜绿假单胞菌分泌的E3连接酶 | Roberts, C. G. | N/A | A functional screen for ubiquitin regulation identifies an E3 ligase secreted by Pseudomonas aeruginosa | |
| 系统基因组引导下发现古菌与细菌之间的拮抗相互作用 | Strock, R. | N/A | Systematic genome-guided discovery of antagonistic interactions between archaea and bacteria | |
| APEX2 细菌中RNA的邻近标记 | Yassine, H. | N/A | APEX2 proximity labeling of RNA in bacteria | |
| 位于VIM-2活性位点附近的保守辅助残基影响其金属β-内酰胺酶活性。 | Jain, D. | N/A | Conserved ancillary residues situated proximally to the VIM-2 active site affect its metallo β-lactamase activity | |
| 接种物大小对阿维巴坦-阿奇霉素组合在小鼠腹膜炎模型中体内活性的影响，该模型由表达CTX-M-15和NDM-1的大肠杆菌引起 | Benchetrit, L. | N/A | Impact of the inoculum size on the in vivo activity of the aztreonam-avibactam combination in a murine model of peritonitis due to Escherichia coli expressing CTX-M-15 and NDM-1 | |
| 微囊藻毒素通过社群过滤和影响交叉喂养互动来塑造微囊藻的藻圈。 | Grosse, R. | N/A | Microcystin shapes the Microcystis phycosphere through community filtering and by influencing cross-feeding interactions | |
| 帽非依赖性翻译指导原生动物寄生虫刚地弓形虫应激诱导的分化 | Dey, V. | N/A | Cap-independent translation directs stress-induced differentiation of the protozoan parasite Toxoplasma gondii | |
| 痤疮丙酸杆菌适应人类生活的特性提供了一种新的痤疮丙酸杆菌感染的生物标志物。 | Shafiuddin, M. | N/A | Cutibacterium adaptation to life on humans provides a novel biomarker of C. acnes infections. | |
| U2AF调控核编码线粒体mRNA的翻译和定位 | Garcia, G. R. | N/A | U2AF regulates the translation and localization of nuclear-encoded mitochondrial mRNAs | |
| 核心剪接结构和早期剪接体识别决定了微外显子对SRRM3/4的敏感性 | Bonnal, S. | N/A | Core splicing architecture and early spliceosomal recognition determine microexon sensitivity to SRRM3/4 | |
| 利用面部侧面相似性改进人工智能驱动的海龟照片识别系统 | Adam, L. | N/A | Exploiting facial side similarities to improve AI-driven sea turtle photo-identification systems | |
| 利用PiggyBac介导的转基因技术与CRISPR/Cas9敲除技术在大蜡螟（Galleria mellonella）中的应用 | Pearce, J. C. | N/A | PiggyBac mediated transgenesis and CRISPR/Cas9 knockout in the greater waxmoth, Galleria mellonella | |
| 细胞衍生基质力学作为胶原蛋白VI相关先天性肌营养不良症的功能性读数 | White, T. | N/A | Cell-derived matrices mechanics as a functional read-out in Collagen VI-related Congenital Muscular Dystrophies | |
| 喹啉协同作用与用量减少：一项药效动力学相互作用研究 | Sadouki, Z. | N/A | Quinoline synergy and reduced use: a study of pharmacodynamic interactions | |
| 利用活体叶片切片成像技术分析C4植物叶肉细胞中依赖于维管束鞘细胞的叶绿体运动 | Kato, Y. | N/A | Bundle sheath cell-dependent chloroplast movement in mesophyll cells of C4 plants analyzed using live leaf-section imaging | |
| DNA模板空间控制蛋白水解靶向嵌合体用于CyclinD1-CDK4/6复合物蛋白降解 | Zheng, R. | N/A | DNA-templated spatially controlled proteolysis targeting chimeras for CyclinD1-CDK4/6 complex protein degradation | |
| 来自结核分枝杆菌临床分离株的MHC I类/II类限制性T细胞表位：结核病疫苗开发的潜在候选者 | Sharma, N. | N/A | MHC class I / II restricted T cell epitopes from clinical isolate of Mycobacterium tuberculosis: A potential candidate for vaccine development for Tuberculosis | |
| 光合作用由含有天线的视紫红质在浮游的Asgard古菌中进行 | Tzlil, G. | N/A | Light-harvesting by antenna-containing rhodopsins in pelagic Asgard archaea | |
| 人巨细胞病毒vGPCR UL33对于上皮细胞中高效裂解复制至关重要 | Freeman, M. R. | N/A | The Human Cytomegalovirus vGPCR UL33 is Essential for Efficient Lytic Replication in Epithelial Cells | |
| 通过多元素和锶同位素比率增强木材溯源性：来自东阿尔卑斯山的一个例子 | Aguzzoni, A. | N/A | Enhancing timber traceability via multielement and strontium isotope ratio: An example from the Eastern Alps | |
| metagWGS是一种综合工作流程，利用Illumina或PacBio HiFi读取数据来分析宏基因组数据。 | Mainguy, J. | N/A | metagWGS, a comprehensive workflow to analyze metagenomic data using Illumina or PacBio HiFi reads | |
| YTHDF1通过促进EEF1G翻译，以m6A依赖的方式促进肺腺癌进展 | Wang, L. | N/A | YTHDF1 Facilitates Lung Adenocarcinoma Progression via Promotion of EEF1G Translation in a m6A-Dependent Manner | |
| # BioRxiv 2024-09-17 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 先前的脑电图标记了跨试验的专注和心智游移心理状态 | Nakatani, C. | N/A | Prior EEG marks focused and mind-wandering mental states across trials | |
| 抑制ABCB7通过触发铁死亡增强顺铂在儿童3型髓母细胞瘤中的反应 | Kanchan, R. K. | N/A | Repressing ABCB7 Potentiates Cisplatin Response in Pediatric Group 3 Medulloblastoma by Triggering Ferroptosis | |
| 灵长类动物主要组织相容性复合体中的古老跨物种多态性 | Fortier, A. L. | N/A | Ancient Trans-Species Polymorphism at the Major Histocompatibility Complex in Primates | |
| 一种军团菌肺炎杆菌效应蛋白阻碍宿主基因沉默以促进毒力 | Toinon, J. | N/A | A Legionella pneumophila effector impedes host gene silencing to promote virulence | |
| 基于细胞外基质的一个简单建模框架 | Metzcar, J. | N/A | A simple framework for agent-based modeling with extracellular matrix | |
| 通过深度挖掘宏基因组基序来设计工程噬菌体 | Huss, P. | N/A | Engineering bacteriophages through deep mining of metagenomic motifs | |
| 在生态学中追求新奇 | Ottaviani, G. | N/A | On the quest for novelty in ecology | |
| 撤回：靶心与标准注视十字对眼球运动和从脑电图分类自然图像的影响 | Häberle, G. | N/A | WITHDRAWN: The influence of the bullseye versus standard fixation cross on eye movements and classifying natural images from EEG | |
| 天冬酰胺的供应调控B细胞的体内平衡 | Yazicioglu, Y. F. | N/A | Asparagine availability controls B cell homeostasis | |
| 拓扑异构酶3β在减轻细胞应激中的RNA靶点和功能 | Teimuri, S. | N/A | RNA Targets and Function of Topoisomerase 3β in Reducing Cellular Stress | |
| 利用基于HHpred的方法对SARS-CoV-2蛋白进行重新注释，为更深入理解这种病毒开辟了新的途径。 | Brezellec, P. | N/A | Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus | |
| 筛选人类可药物基因组确定ABHD17B为肝星状细胞中的抗纤维化靶点 | Li, W. | N/A | Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells | |
| 通过缝隙连接的细胞类型特异性核苷酸共享影响对复制应激的敏感性 | Boumard, B. | N/A | Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress | |
| 与认知控制相关的大脑活动的寿命轨迹 | Yang, G. | N/A | The Lifespan Trajectories of Brain Activities Related to Cognitive Control | |
| CNTD1在女性减数分裂的I期进展和交叉点的指定中起着关键作用，对于建立卵巢储备至关重要。 | Wood, A. | N/A | CNTD1 plays crucial roles in prophase I progression and crossover designation during female meiosis and is critical for establishing the ovarian reserve | |
| 神经生理学证据表明，感觉预测误差驱动了言语感觉运动适应。 | Kim, K. S. | N/A | Neurophysiological evidence of sensory prediction errors driving speech sensorimotor adaptation | |
| 携带包膜的内源性逆转录病毒在后生动物中的前寒武纪起源 | Chary, S. | N/A | Pre-Cambrian origin of envelope-carrying endogenous retroviruses in metazoans | |
| 前额叶皮层中不同的奖励线索表征导致了青少年和成年人在奖励动机上的差异 | Manzano Nieves, G. | N/A | Divergent reward cue representations in prefrontal cortex underlie differences in reward motivation between adolescents and adults | |
| 脊髓V1抑制性中间神经元簇在出生日期、对运动神经元的投射以及异质性方面存在差异。 | Worthy, A. E. | N/A | Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons and heterogeneity | |
| 金黄色葡萄球菌通过强大的丙氨酸消旋酶活性，抵御有机酸阴离子介导的肽聚糖交联抑制作用。 | Panda, S. | N/A | Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity | |
| 任务无关的阶段，而非对比度变化，在视觉感知学习中解锁了泛化 | Akkoyunlu, B. | N/A | Task-irrelevant phase but not contrast variability unlocks generalization in visual perceptual learning | |
| 从分子量分布的矩差推断代谢速率 | Tuobang, L. | N/A | Infer metabolic velocities from moment differences of molecular weight distributions | |
| HairSplitter：从长且有噪声的读取片段中组装单体型 | Faure, R. | N/A | HairSplitter: haplotype assembly from long, noisy reads | |
| 在感知和工作记忆内容之间转移注意力的神经动力学 | Gresch, D. | N/A | Neural dynamics of shifting attention between perception and working-memory contents | |
| 脑皮质神经元对脑震荡的转录反应揭示了损伤后的不同命运 | Alkaslasi, M. R. | N/A | The transcriptional response of cortical neurons to concussion reveals divergent fates after injury | |
| 通过单核苷酸分辨率建模解析转录起始的核心启动子语法 | He, A. Y. | N/A | Dissection of core promoter syntax through single nucleotide resolution modeling of transcription initiation | |
| 不同物种对四种细菌病原体易感性的系统发育信号变化 | Sun, H. | N/A | Varying phylogenetic signal in susceptibility to four bacterial pathogens across species of Drosophilidae | |
| 二聚体-单体转变定义了一种超耐热肽聚糖水解酶，该酶通过源自溶菌素的抗菌肽引导筛选从细菌蛋白质组中挖掘得到。 | Zhang, L. | N/A | Dimer-monomer transition defines a hyper-thermostable peptidoglycan hydrolase mined from bacterial proteome by lysin-derived antimicrobial peptide-primed screening | |
| 预测疼痛基因：利用概率分类器和交互网络进行多模态数据整合 | Zhao, N. | N/A | Predicting pain genes: multi-modal data integration using probabilistic classifiers and interaction networks | |
| 河口梯度下潮汐湿地土壤有机碳储量及其稳定机制 | Neiske, F. | N/A | Soil organic carbon stocks and stabilization mechanisms in tidal marshes along estuarine gradients | |
| 使用独特标记基因集对scRNA-seq数据进行自动细胞注释 | Truong, L. | N/A | Automated cell annotation in scRNA-seq data using unique marker gene sets | |
| 单细胞基因表达的综合分析：一种全面的数据库方法 | Truong, L. | N/A | Integrative analysis of single-cell gene expression: A comprehensive database approach | |
| 一个用于简化序列分析的进化统计工具包，支持在网页上进行客户端处理 | Karagöl, A. | N/A | An Evolutionary Statistics Toolkit for Simplified Sequence Analysis on Web with Client-Side Processing | |
| 在德国监测自由生活的蜜蜂群落：对栖息地偏好、存活率及公民科学可靠性的洞察 | Rutschmann, B. | N/A | Monitoring free-living honeybee colonies in Germany: Insights into habitat preferences, survival rates, and Citizen Science reliability | |
| 睡眠-觉醒周期中突触稳态的边界条件 | Kinoshita, F. L. | N/A | Boundary conditions for synaptic homeodynamics during the sleep-wake cycle | |
| haCCA：空间转录组和代谢组的多模块整合。 | Shen, X. | N/A | haCCA: Multi-module Integrating of spatial transcriptomes and metabolomes. | |
| 提高行为振荡检测的灵敏度：对Brookshire（2022）AR-替代方法的改进 | Harris, A. M. | N/A | Detecting behavioural oscillations with increased sensitivity: A modification of Brookshire's (2022) AR-surrogate method | |
| SQANTI-reads：一种用于多样本长读长RNA-seq实验中长读长数据质量评估的工具。 | Keil, N. | N/A | SQANTI-reads: a tool for the quality assessment of long read data in multi-sample lrRNA-seq experiments. | |
| 训练对实验性发声学习缺乏经验的斑海豹进行发声学习实验 | Duengen, D. | N/A | Training Experimentally Naive Seals for Vocal Learning Experiments | |
| 全基因组搜索鉴定可能赋予臭虫（Cimex lectularius）杀虫剂抗性的基因突变 | Toga, K. | N/A | Genome-wide Search for Gene Mutations likely Conferring Insecticide Resistance in the Common Bed Bug, Cimex lectularius | |
| 鸭子接种高致病性禽流感疫苗的积极效果，法国2023-24年 | Guinat, C. | N/A | Promising effects of duck vaccination against highly pathogenic avian influenza, France 2023-24 | |
| 评估生理指标在利用对比问题测试（CQT）检测欺骗中的应用 | Rashid, A. M. S. | N/A | Evaluating Physiological Indicators in Detecting Deception using the Comparison Question Test (CQT) | |
| 质子结合的变构调节使囊泡谷氨酸转运体具有Cl-激活和谷氨酸选择性 | Borghans, B. | N/A | Allosteric modulation of proton binding confers Cl- activation and glutamate selectivity to vesicular glutamate transporters | |
| CRISPRoff表观遗传编辑技术：在人类细胞中实现可编程基因沉默，无需DNA断裂 | Pattali, R. K. | N/A | CRISPRoff epigenetic editing for programmable gene silencing in human cells without DNA breaks | |
| 欧洲旧石器时代晚期气候变化下的人口反应 | Schmidt, I. | N/A | Demographic responses to climatic changes during the Final Palaeolithic in Europe | |
| 参考样本的表观基因组、转录组和蛋白质组特征分析 | Nepal, C. | N/A | Epigenomic, transcriptomic and proteomic characterizations of reference samples | |
| 注意力机制和状态空间基因组语言模型中标记化影响的比较 | Lindsey, L. M. | N/A | A Comparison of Tokenization Impact in AttentionBased and State Space Genomic Language Models | |
| SVbyEye：一种用于表征全基因组组装间结构变异的视觉工具 | Porubsky, D. | N/A | SVbyEye: A visual tool to characterize structural variation among whole-genome assemblies | |
| 海洋酵母对基于昆布多糖的底物的利用和降解表明它们在微生物循环动力学中具有生态位特异性的作用。 | Arslan-Gatz, B. | N/A | Utilization and degradation of laminarin-based substrates by marine yeasts suggests their niche-specific role in microbial loop dynamics. | |
| 连接组蛋白调控多能造血干细胞和祖细胞在髓系与淋巴系分化中的分支 | Karatepe, K. | N/A | Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors | |
| 朝着解释养殖北京鸭的繁殖差距迈进 | Beyts, C. H. | N/A | Towards explaining the fertility gap in farmed Pekin ducks | |
| 全球树冠结构的谱系 | Jucker, T. | N/A | The global spectrum of tree crown architecture | |
| 泛癌线粒体DNA修复基因集的遗传分析 | Dong, A. | N/A | Pan-Cancer Genetic Analysis of Mitochondrial DNA Repair Gene Set | |
| 脊髓小脑性共济失调2型（SCA2）脑萎缩的模式与分期：来自ENIGMA-共济失调研究的MRI体积测量 | Robertson, J. W. | N/A | The Pattern and Staging of Brain Atrophy in Spinocerebellar Ataxia Type 2 (SCA2): MRI Volumetrics from ENIGMA-Ataxia | |
| 蜱虫中一个单一的祖先ANP32位点产生了多种蛋白质变体，这些变体均支持Thogoto病毒聚合酶的功能。 | Zhang, Z. | N/A | A single ancestral ANP32 locus in ticks creates multiple protein variants that all support the Thogoto virus polymerase | |
| 高通量优化的基于质粒编辑的内源性蛋白质标记技术，用于蛋白质定位的池化成像 | Sanchez, H. M. | N/A | High-throughput optimized prime editing mediated endogenous protein tagging for pooled imaging of protein localization | |
| 使用蛋白质纳米笼在活细胞中定量比较单体StayGold变体 | Viola, G. | N/A | Quantitative Comparison of Monomeric StayGold Variants Using Protein Nanocages in Living Cells | |
| 人诱导多能干细胞（iPSC）衍生的脑周细胞在炎症激活方面与原代人脑周细胞表现出差异。 | McCullough, S. | N/A | Human iPSC-derived brain pericytes exhibit differences in inflammatory activation compared to primary human brain pericytes | |
| 自噬通过调控嘌呤核苷信号通路，起到抑制肥胖相关纤维化的作用。 | Piletic, K. | N/A | Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling | |
| HP1α驱动的相分离与异染色质损伤修复途径选择 | Bohra, D. | N/A | HP1α-driven Phase Separation and Repair Pathway Choice in Response to Heterochromatin Damage | |
| 重新审视肠球菌属黄褐肠球菌及相关物种的分类 | Soares de Medeiros Lima, M. M. | N/A | Revisiting the taxonomy of Enterococcus casseliflavus and related species | |
| 青络饮诱导的SIRT1抑制有助于佐剂诱导的关节炎大鼠免疫改善 | Zuo, J. | N/A | Qing-Luo-Yin-induced SIRT1 inhibition contributes to the immune improvement of adjuvant-induced arthritis rats | |
| 更新了包含撤稿数据的科学领域标准化引用指标作者数据库 | Ioannidis, J. | N/A | Updated science-wide author databases of standardized citation indicators including retraction data | |
| H3K4me3结合的ALFIN-LIKE蛋白招募SWR1以在基因体内沉积H2A.Z | Xu, L. | N/A | The H3K4me3 binding ALFIN-LIKE proteins recruit SWR1 for gene-body deposition of H2A.Z | |
| 通过休眠的进化稳定波动的人口动态 | Miller, Z. R. | N/A | Stabilization of fluctuating population dynamics via the evolution of dormancy | |
| 原发性口腔鳞状细胞癌的蛋白质基因组特征揭示了与淋巴结转移相关的细胞外基质重塑和免疫抑制微环境 | Liu, Y. | N/A | Proteogenomic Characterization of Primary Oral Squamous Cell Carcinomas Unveils the Extracellular Matrix Remodeling and Immunosuppressive Microenvironment Linked with Lymph Node Metastasis | |
| 一种统一的贝叶斯方法用于转录组关联研究 | Khan, A. K. | N/A | A unified Bayesian approach to transcriptome-wide association study | |
| 加速昆虫嗅觉受体配体的发现 | Comte, A. | N/A | Accelerating Ligand Discovery for Insect Odorant Receptors | |
| 通过DeepFuseNMF实现空间转录组学数据的可解释高分辨率降维 | Tang, J. | N/A | Interpretable high-resolution dimension reduction of spatial transcriptomics data by DeepFuseNMF | |
| 枝角类动物可保障替代急性鱼类毒性测试的生物检测方法的使用：重点关注神经毒性 | Schuer, C. | N/A | Daphnids Can Safeguard the Use of Alternative Bioassays to the Acute Fish Toxicity Test: A Focus on Neurotoxicity | |
| 在加拿大引发高发播散性淋球菌感染的分离株中，表型多样性与共享的基因组决定因素 | Binepal, G. | N/A | Phenotypic diversity and shared genomic determinants among isolates causing a large incidence of disseminated gonococcal infections in Canada | |
| 子宫肌层中PRICKLE1的缺失导致小鼠生育力下降、子宫肌层结构异常及细胞外基质沉积异常。 | Roberts, E. | N/A | Loss of PRICKLE1 in the myometrium leads to reduced fertility, abnormal myometrial architecture, and aberrant extracellular matrix deposition in mice. | |
| 在寒冷环境中发育使得鸟类线粒体更容易受到热应激的影响。 | Correia, M. | N/A | Development in the cold renders bird mitochondria more susceptible to heat stress | |
| 在计算机探索中，Amubarvimab和Romlusevimab对SARS-COV-2变种的中和机制 | Huan, X. | N/A | In computer explore The neutralization mechanism of Amubarvimab and Romlusevimab against SARS-COV-2 mutants | |
| 一种主要真菌病原体在全球收集物中的热适应性 | Minana-Posada, S. | N/A | Thermal adaptation in worldwide collections of a major fungal pathogen | |
| p53通过调节核结构来降低致癌物敏感性和突变潜能 | King, D. A. | N/A | p53 Regulates Nuclear Architecture to Reduce Carcinogen Sensitivity and Mutagenic Potential | |
| 针对癌症相关糖基化进行胃肠道和妇科癌症的过继T细胞治疗 | Zingg, A. | N/A | Targeting cancer-associated glycosylation for adoptive T cell therapy of gastro-intestinal and gynecological cancers | |
| 抑制谷氨酰胺酶可诱导治疗诱导的衰老黑色素瘤细胞的衰老消解。 | Kim, J. | N/A | Inhibition of glutaminase elicits senolysis in therapy-induced senescent melanoma cells. | |
| 在Pristionchus中，发育转录组学揭示了可塑性基因调控网络的逻辑 | Reich, S. | N/A | Developmental transcriptomics in Pristionchus reveals the logic of a plasticity gene regulatory network | |
| 纹状体中快速放电中间神经元的功能性后果 | Guo, L. | N/A | Functional consequences of fast-spiking interneurons in striatum | |
| 一种结合了树突非线性特性和反向传播动作电位的V1神经模型 | Rentzeperis, I. | N/A | A neural model for V1 that incorporates dendritic nonlinearities and back-propagating action potentials | |
| 层流功能定量磁化率成像的可行性 | Straub, S. | N/A | Feasibility of laminar functional quantitative susceptibility mapping | |
| 全脑微卒中影响海马记忆回路的稳定性 | Heiser, H. | N/A | Brain-wide microstrokes affect the stability of memory circuits in the hippocampus | |
| 使用条件性GeneSwitch驱动器扩展果蝇血细胞会影响幼虫血细胞功能，但不会调节成虫的寿命或感染后的存活率。 | Hayman, D. J. | N/A | Expansion of Drosophila haemocytes using a conditional GeneSwitch driver affects larval haemocyte function, but does not modulate adult lifespan or survival from infection | |
| 倾斜错觉源于在上下文边界处对神经编码资源的高效重新分配。 | Zhang, L.-Q. | N/A | The tilt illusion arises from an efficient reallocation of neural coding resources at the contextual boundary | |
| 通过眶额皮层自上而下的输入对感觉反应进行预测性过滤 | Tsukano, H. | N/A | Predictive filtering of sensory response via orbitofrontal top-down input | |
| 通过解剖和显微计算机断层扫描识别出的人类三叉神经和面神经分支及孔道的变异 | Grimes, H. L. | N/A | Variations in human trigeminal and facial nerve branches and foramina identified by dissection and microcomputed tomography | |
| 海马体中人口活动的稀疏性在三突触回路和背腹轴上是任务不变的。 | Lee, J. Q. | N/A | Sparsity of population activity in the hippocampus is task-invariant across the tri-synaptic circuit and dorsal-ventral axis | |
| 从前馈到反馈节奏的表征转变，标志着自然视觉中现象学整合的指标。 | Chen, L. | N/A | Representational shifts from feedforward to feedback rhythms index phenomenological integration in natural vision | |
| 单极刷状细胞接收到的真实苔藓纤维输入模式，能够引发一系列时间响应，这些响应由不同谷氨酸受体介导的成分组成。 | Huson, V. | N/A | Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate receptors | |
| 行为控制的神经递质基础 | Ballard, I. C. | N/A | A dopaminergic basis of behavioral control | |
| 皮质连接支持运动同步，以响应前额叶-颞叶网络中的听觉和视觉节奏。 | Lu, Y. | N/A | Cortical connectivity supports motoric synchronization to both auditory and visual rhythms in a frontal-temporal network | |
| 清醒大鼠内脏操作的神经影像学模型 | Cramer, S. R. | N/A | Neuroimaging model of visceral manipulation in awake rat | |
| 胎儿期暴露于四氢大麻酚（THC）后，急性应激的性别特异性适应不良反应受多巴胺介导。 | Serra, V. | N/A | Sex-specific maladaptive responses to acute stress upon in utero THC exposure are mediated by dopamine | |
| 基于MRI的阿尔茨海默病分类的可解释AI模型比较 | Chattopadhyay, T. | N/A | Comparison of Explainable AI Models for MRI-based Alzheimer's Disease Classification | |
| 背侧中缝核中的GABA能神经元调节小鼠的社会等级 | Fang, G. | N/A | GABAergic neurons in the dorsal raphe nucleus regulate social hierarchy in mice | |
| 杏仁核刺激通过前扣带皮层中非典型PKC的持续激活，将短期记忆转化为远程记忆。 | Almaguer-Melian, W. | N/A | Amygdala stimulation transforms short-term memory into remote memory by persistent activation of atypical PKC in the anterior cingulate cortex | |
| 尽管关键标记基因发生了显著变化，颗粒性后海马皮质的独特转录组细胞类型在鼠和鼠之间得以保留 | Brooks, I. A. | N/A | Unique Transcriptomic Cell Types of the Granular Retrosplenial Cortex are Preserved Across Mice and Rats Despite Dramatic Changes in Key Marker Genes | |
| 星形胶质细胞糖皮质激素受体介导应激后性特异性活动变化 | Depaauw-Holt, L. | N/A | Astrocyte glucocorticoid receptors mediate sex-specific changes in activity following stress | |
| 高分辨率活体运动学追踪与可注射荧光纳米颗粒 | Ulutas, E. Z. | N/A | High-resolution in vivo kinematic tracking with injectable fluorescent nanoparticles | |
| 在小鼠齿状回中，5-HT7受体的激活选择性地增强了GABA能抑制作用，这种抑制作用针对的是门区的苔藓细胞，而不会影响穿通路径突触的可塑性。 | Siwiec, M. | N/A | Activation of 5-HT7 receptors in the mouse dentate gyrus selectively enhances GABAergic inhibition of hilar mossy cells without affecting plasticity at the perforant path synapse | |
| 神经元中内源性大麻素过多对认知功能有害。 | Zhu, D. | N/A | Overabundant endocannabinoids in neurons are detrimental to cognitive function | |
| Notch/无毛通路对原肠胚形成前sog转录爆发的调控 | Fenelon, K. D. | N/A | Notch/Hairless Pathway Modulation of sog Transcriptional Bursting in Prelude to Gastrulation | |
| 单细胞多组学、空间转录组学和系统扰动揭示神经嵴命运决定的电路 | Hu, Z. | N/A | Single-cell multi-omics, spatial transcriptomics and systematic perturbation decode circuitry of neural crest fate decisions | |
| 肉类转移遵循几内亚狒狒多层次社会中的社会关系，但与雄性繁殖成功无关。 | O'Hearn, W. J. | N/A | Meat transfers follow social ties in the multi-level society of Guinea baboons but are not related to male reproductive success | |
| 跳蛛不会被周边漂移错觉所迷惑 | De Agro, M. | N/A | Jumping spiders are not fooled by the peripheral drift illusion | |
| 温暖水域中猎物显著性的增强缓解了浊度对捕食者的视觉限制 | Zanghi, C. | N/A | Enhanced conspicuousness of prey in warmer water mitigates the visual constraint of turbidity for predators | |
| 注意缺陷多动障碍儿童和青少年的大脑边缘系统白质：一项纵向扩散磁共振成像分析 | Connaughton, M. | N/A | Limbic System White Matter in Children and Adolescents with ADHD: A Longitudinal Diffusion MRI Analysis | |
| 阿尔茨海默病的病理学破坏了在小鼠进行风险觅食决策期间，灵活的位置细胞编码和海马-前额叶神经动力学。 | Kim, E. J. | N/A | Alzheimer's pathology disrupts flexible place cell coding and hippocampal-prefrontal neural dynamics during risky foraging decisions in mice | |
| 皮层状态对早期视觉皮层反应变异性的贡献：一种系统识别方法 | Sooriyaarachchi, J. | N/A | Cortical state contributions to response variability in the early visual cortex: A system identification approach | |
| 面部表情与颜色在调节EPR P3中的相互作用 | Hasegawa, Y. | N/A | Interaction between facial expression and color in modulating EPR P3 | |
| MPXV以I型干扰素敏感的方式感染人外周血单核细胞 | Bosquillon de Jarcy, L. | N/A | MPXV Infects Human PBMCs in a Type I Interferon-Sensitive Manner | |
| SARS-Cov-2 N蛋白的亲和标签免费纯化及其与ssDNA复合物的晶体结构 | Maiti, A. | N/A | Affinity tag free purification of SARS-Cov-2 N protein and its crystal structure in complex with ssDNA | |
| PangeBlocks：通过最大块实现泛基因组图的自定义构建 | Bonizzoni, P. | N/A | PangeBlocks: customized construction of pangenome graphs via maximal blocks | |
| 基于相分离合成细胞器的代谢物响应转录调控 | Jerez-Longres, C. | N/A | Metabolite-responsive Control of Transcription by Phase Separation-based Synthetic Organelles | |
| 一种用于编程干细胞内源基因多步骤激活的模块化系统 | Puppala, A. K. | N/A | A modular system for programming multistep activation of endogenous genes in stem cells | |
| 在聚球藻PCC 7002中实现高效转化与基因表达 | Hren, A. P. | N/A | High-efficiency transformation and gene expression in Picosynechococcus sp. PCC 7002 | |
| 合成细胞模型中膜相分离与细菌分裂蛋白动态之间的相互依赖关系 | Kanwa, N. | N/A | Mutual dependence between membrane phase separation and bacterial division protein dynamics in synthetic cell models | |
| 炎症和转移性癌症中肺淋巴管的原位成像 | Cleary, S. J. | N/A | Intravital imaging of pulmonary lymphatics in inflammation and metastatic cancer | |
| 一个涵盖5000年的古代人类口腔微生物组研究的广泛考古牙结石数据集 | Standeven, F. J. | N/A | An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research | |
| 斯里兰卡人感染的细螺旋体博氏菌株的基因组分析揭示了PF07598基因家族谱系的扩展，其整体基因组缩减程度低于牛感染的菌株。 | Senavirathna, I. | N/A | Genomic Analysis of Human-infecting Leptospira borgpetersenii isolates in Sri Lanka expanded PF07598 gene family repertoire, less overall genome reduction than bovine isolates | |
| 一种慢性小鼠肺部鲍曼不动杆菌感染模型，可用于研究晚期毒力因子、长期抗生素治疗以及多菌种感染。 | Jackson-Litteken, C. D. D. | N/A | A chronic murine model of pulmonary Acinetobacter baumannii infection enabling the investigation of late virulence factors, long-term antibiotic treatments, and polymicrobial infections | |
| 人类肠道细菌对PFAS的广泛积累 | Lindell, A. E. | N/A | Extensive PFAS accumulation by human gut bacteria | |
| 艰难梭菌的ruberythrin基因座能有效解毒活性氧物质。 | Knop, R. | N/A | A rubrerythrin locus of Clostridioides difficile efficiently detoxifies reactive oxygen species | |
| 标题：坦桑尼亚北部野生动物保护区附近牛群非洲动物锥虫病治疗失败原因的纵向观察（单队列）研究 | Richards, S. | N/A | Title Longitudinal Observational (single cohort) Study on the Causes of Trypanocide Failure in cases of African Animal Trypanosomosis in Cattle Near Wildlife Protected Areas of Northern Tanzania | |
| RNA聚合酶II在活性启动子上协调组蛋白去乙酰化 | Hoffman, J. A. | N/A | RNA Polymerase II coordinates histone deacetylation at active promoters | |
| Transportin-1介导的PPARg核运输机制的结构解析 | TOMA-FUKAI, S. | N/A | Structural insight into the nuclear transportation mechanism of PPARg by Transportin-1 | |
| 针对FUS-ALS聚集，使用蛋白酶体抑制剂进行靶向治疗 | Younis, A. | N/A | Targeting FUS-ALS aggregation with Proteasome Inhibitors | |
| 通过激活mTOR/TFEB增强溶酶体功能可减少早期年龄相关性黄斑变性中的脂褐素样颗粒 | Falcao, A. S. | N/A | Enhancing lysosome function via mTOR/TFEB activation reduces lipofuscin-like granules in early Age-related Macular Degeneration | |
| pytom-match-pick：模板匹配中用于自动化分类的tophat-transform约束 | Chaillet, M. L. | N/A | pytom-match-pick: a tophat-transform constraint for automated classification in template matching | |
| 评估埃博拉病毒在刚果民主共和国赤道省的传播：一项关于野生动物与人类互动的一体化健康调查 | van Vredendaal, R. | N/A | Assessing Ebola Virus Circulation in the Tshuapa Province (Democratic Republic of the Congo): A One Health Investigation of Wildlife and Human Interactions | |
| 将种内变异整合到种群动态中，揭示了相互作用的物种如何在互利共生群落中持续存在 | Arroyo-Correa, B. | N/A | Integrating intraspecific variation into population dynamics reveals how interacting species persist in mutualistic communities | |
| 气候适应性有助于全球入侵 | Gamba, D. | N/A | Local adaptation to climate facilitates a global invasion | |
| 过去5000年葡萄牙的遗传史 | Roca-Rada, X. | N/A | The genetic history of Portugal over the past 5,000 years | |
| 利用直接胶原纤维模型捕捉巩膜各向异性。将微观结构与宏观力学特性联系起来。 | Ji, F. | N/A | Capturing sclera anisotropy using direct collagen fiber models. Linking microstructure to macroscopic mechanical properties. | |
| 使用可调细胞外基质水凝胶系统精准修复特定区域的半月板损伤 | Lee, S.-H. | N/A | Precision Repair of Zone-Specific Meniscal Injuries Using a Tunable Extracellular Matrix-Based Hydrogel System | |
| CRAK-Velo：染色质可及性动力学整合提升RNA速度估算 | El Kazwini, N. | N/A | CRAK-Velo: Chromatin Accessibility Kinetics integration improves RNA Velocity estimation | |
| 短读长纳米孔测序的精确碱基识别 | Wang, Z. | N/A | The Precise Basecalling of Short-Read Nanopore Sequencing | |
| 尽管存档切片存在噪声，机器学习仍能收敛于黑色素细胞形态 | Tada, M. | N/A | Machine-learning convergent melanocytic morphology despite noisy archival slides | |
| 连接小管中的通路流动引起传入小动脉的血管舒张。 | Wang, H. | N/A | Luminal Flow in the Connecting Tubule induces Afferent Arteriole Vasodilation | |
| 利用分裂mVenus方法在植物系统中实施Ribo-BiFC技术的实现 | Raabe, K. | N/A | Implementation of Ribo-BiFC method to plant systems using a split mVenus approach | |
| 在鼠伤寒沙门氏菌中可逆地切除wzy位点可能有助于在噬菌体捕食后恢复 | Charity, O. J. | N/A | Reversible excision of the wzy locus in Salmonella Typhimurium may aid recovery following phage predation | |
| 利用工程化的连接选择性去泛素化酶解码多泛素化对KV7.1功能表达的调控 | Shanmugam, S. K. | N/A | Decoding polyubiquitin regulation of KV7. 1 functional expression with engineered linkage-selective deubiquitinases | |
| 利用高分辨率基因表达谱揭示被子植物中全基因组加倍后的保守进化响应 | Leal, J. L. | N/A | Conserved Evolutionary Response to Whole Genome Duplication in Angiosperms Revealed Using High Resolution Gene Expression Profiling | |
| 人类凝聚蛋白亚基的分子动力学模拟识别出DNA结合位点及其在DNA环挤出中的潜在作用 | Gu, C. | N/A | Molecular dynamics simulations of human cohesin subunits identify DNA binding sites and their potential roles in DNA loop extrusion | |
| # BioRxiv 2024-09-16 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| Tasselyzer是一种基于PlantCV的机器学习方法，用于量化玉米花药的伸展情况。 | Teng, C. | N/A | Tasselyzer, a machine learning method to quantify maize anther exertion, based on PlantCV | |
| 3'UTR介导的、激酶近端的mRNA降解通过抑制C/EBPβ的磷酸化/激活来抑制肿瘤细胞的衰老 | Salotti, J. | N/A | 3'UTR-directed, kinase proximal mRNA decay inhibits C/EBPβ phosphorylation/activation to suppress senescence in tumor cells | |
| 线粒体铁通过MFRN1的转运对于红细胞周期的进展是必需的。 | Perfetto, M. | N/A | Mitochondrial iron transport via MFRN1 is required for erythroid cell cycle progression | |
| 单粒子追踪揭示了PIEZO1扩散的异质性 | Ly, A. T. | N/A | Single-particle tracking reveals heterogeneous PIEZO1 diffusion | |
| 水模型对酶通道结构和动力学的影响 | Agrawal, N. | N/A | Impact of water models on structure and dynamics of enzyme tunnels | |
| 快速分类与对伤害意图的精细学习：血清素与种族偏见的作用 | Moutoussis, M. | N/A | Rapid classification vs. refined learning about harm intent: Roles of serotonin and racial bias | |
| 不同的大脑皮层突触前网络构成了单个皮层神经元的功能特性。 | Inacio, A. R. | N/A | Distinct brain-wide presynaptic networks underlie the functional identity of individual cortical neurons | |
| 血餐来源和季节性对尖音库蚊（双翅目：蚊科）繁殖特性的影响 | Rucci, K. A. | N/A | Effects of blood meal source and seasonality on reproductive traits of Culex quinquefasciatus (Diptera: Culicidae) | |
| 与日本脑炎病毒相关的景观反映了澳大利亚和中印度-太平洋地区水鸟物种的功能生物地理学。 | Walsh, M. | N/A | Landscapes associated with Japanese encephalitis virus reflect the functional biogeography of waterbird species across Australia and the Central Indo-Pacific region | |
| SACNet：一种具有先验神经解剖学约束的多尺度微分同胚卷积配准网络，用于回波平面成像中的灵活磁敏感伪影校正 | Zeng, Z. | N/A | SACNet: A Multiscale Diffeomorphic Convolutional Registration Network with Prior Neuroanatomical Constraints for Flexible Susceptibility Artifact Correction in Echo Planar Imaging | |
| 全细胞多目标单分子超分辨率三维成像与微流控技术和单物镜倾斜光片 | Gagliano, G. | N/A | Whole-cell multi-target single-molecule super resolution imaging in 3D with microfluidics and a single-objective tilted light sheet | |
| 打开物种箱：微观简约的物种形成模型对宏观进化的启示 | Couvert, E. | N/A | Opening the species box: What microscopic parsimonious models of speciation have to say about macroevolution | |
| 肠道微生物群相关的长链脂肪酸硬脂酸抑制结直肠癌 | Tsenkova, M. | N/A | The gut microbiome-linked long chain fatty acid stearate suppresses colorectal cancer | |
| 在整个皮层中，对于自信预测的视觉输入的能量节省 | Hechler, A. | N/A | Energy savings across the cortex for confidently predicted visual input | |
| 肌成纤维细胞增殖受损是病理性产后肺泡简化的核心特征 | Khan, I. S. | N/A | Impaired Myofibroblast Proliferation is a Central Feature of Pathologic Post-Natal Alveolar Simplification | |
| 神经动力学与癫痫发作相关性：破伤风毒素大鼠癫痫模型中神经质量模型的见解 | Zarei Eskikand, P. | N/A | Neural Dynamics and Seizure Correlations: Insights from Neural Mass Models in a Tetanus Toxin Rat Model of Epilepsy | |
| MagIC-Cryo-EM：在异质样本中对稀缺大分子进行磁珠结构测定 | Arimura, Y. | N/A | MagIC-Cryo-EM: Structural determination on magnetic beads for scarce macromolecules in heterogeneous samples | |
| NeuroCSF：一种用于测量人类视觉皮层对比敏感度函数的fMRI方法 | Goulet, L. L. | N/A | NeuroCSF: an fMRI method to measure contrast sensitivity function in human visual cortex | |
| ARX多聚丙氨酸突变在人类皮层和中间神经元发育中的双重效应 | Nieto-Estevez, V. | N/A | Dual effects of ARX poly-alanine mutations in human cortical and interneuron development | |
| 一种转录网络是线粒体生物发生双重基因组协调的基础 | Xu, H. | N/A | A transcription network underlies the dual genomic coordination of mitochondrial biogenesis | |
| 整合的WF-哈丁（WFH）模型解决了分子进化中的许多悖论 | Ruan, Y. | N/A | The integrated WF-Haldane (WFH) model of genetic drift resolving the many paradoxes of molecular evolution | |
| 新型基因编码探针用于通过偏振显微镜对细胞信号传导的功能成像 | Miclea, P. S. | N/A | Novel Genetically Encoded Probes for Functional Imaging of Cell Signaling by Polarization Microscopy | |
| 耐盐黑酵母Hortaea werneckii的异位DNA整合与无标记CRISPR/Cas9策略 | Hernandez-Rodriguez, Y. | N/A | Ectopic DNA integration and marker-free CRISPR/Cas9 strategies for the halotolerant black yeast Hortaea werneckii | |
| PDGFRα信号调控Srsf3转录本结合，影响PI3K信号传导和内体运输 | Forman, T. E. | N/A | PDGFRα signaling regulates Srsf3 transcript binding to affect PI3K signaling and endosomal trafficking | |
| RNA语言模型预测能够增强RNA功能的突变 | Shulgina, Y. | N/A | RNA language models predict mutations that improve RNA function | |
| 心脏分化路线图用于分析可塑性和平衡的谱系承诺 | Snabel, R. R. | N/A | Cardiac differentiation roadmap for analysis of plasticity and balanced lineage commitment | |
| 针对现实世界任务优化的模型揭示了听觉中任务依赖性精确时间编码的必要性。 | Saddler, M. R. | N/A | Models optimized for real-world tasks reveal the task-dependent necessity of precise temporal coding in hearing | |
| 松树、杰克松及其杂交种对真菌病原体松树小蠹菌的遗传结构响应 | Lu, M. | N/A | Genetic architecture underlying response to the fungal pathogen Dothistroma septosporum in lodgepole pine, jack pine, and their hybrids | |
| 1型糖尿病发病前后人类胰腺淋巴组织中的免疫扰动 | Golden, G. J. | N/A | Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset | |
| 在单层和双层中的脂质扩散动力学的比较，涉及脂质层间耦合的背景。 | Mandal, T. | N/A | A comparison of lipid diffusive dynamics in monolayers and bilayers in the context of interleaflet coupling | |
| 社会复杂性对白蚁中自然选择效力的影响 | Roux, C. | N/A | The impact of social complexity on the efficacy of natural selection in termites | |
| 细胞分化调控领鞭毛虫铁吸收 | Leon, F. | N/A | Cell differentiation controls iron assimilation in a choanoflagellate | |
| GLARE：利用表示学习揭示太空飞行转录组中的隐藏模式 | Seo, D. | N/A | GLARE: Discovering Hidden Patterns in Spaceflight Transcriptome Using Representation Learning | |
| 带有不平地形的分带式测力跑步机 | Kuo, A. D. | N/A | A split-belt instrumented treadmill with uneven terrain | |
| 多元化的全球植物油生产能够缓解气候变化，并实现社会与环境的共同效益。 | Zeng, S. | N/A | Diversified global vegetable oil production can mitigate climate change and achieve socio-environmental co-benefits | |
| 肠道血清素迷走神经信号作为微生物群诱发高血压的中介因素 | de Araujo, A. | N/A | Intestinal serotonergic vagal signaling as a mediator of microbiota-induced hypertension | |
| 值班爸爸：疣鼻栖鸭孵蛋首记录 | Scheiber, I. B. R. | N/A | Dads on duty: First account of nest sitting in barnacle ganders | |
| 绿色植物的染色体数目与生殖生命周期：一个系统发生-转录组学的视角 | Dhakal, R. | N/A | Chromosome Numbers and Reproductive Life Cycles in Green Plants: A phylo-transcriptomic perspective | |
| 在欧洲恢复的湿地生态系统中，野化马和牛的栖息地利用与植物群落的功能和结构组成相关 | Lovasz, L. | N/A | Habitat use of rewilded horses and cattle as related to the functional and structural composition of plant communities in a European restored wetland ecosystem | |
| SMURF1/2是WNK1稳定性的新型调控因子 | Jaykumar, A. B. | N/A | SMURF1/2 are novel regulators of WNK1 stability | |
| 通过计算重建实现可扩展的无图像空间基因组学 | Hu, C. | N/A | Scalable imaging-free spatial genomics through computational reconstruction | |
| 谱系限制的机制基础 | Wu, B. | N/A | Mechanistic basis of lineage restriction | |
| 天堂鱼（Macropodus opercularis）作为情感和认知功能的新型转化模型 | Varga, Z. K. | N/A | Paradise fish (Macropodus opercularis) as novel translational model for emotional and cognitive function | |
| 单分子脂质生物传感器减轻内源性效应蛋白的抑制作用 | Holmes, V. | N/A | Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins | |
| 单分子脂质生物传感器减轻内源性效应蛋白的抑制 | Holmes, V. | N/A | Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins | |
| 细菌基因组编码的ParM | Ali, S. | N/A | Bacterial genome encoded ParMs | |
| 鉴定出一种调节免疫反应的真菌抗菌内肽酶 | Machata, S. | N/A | Identification of a fungal antibacterial endopeptidase that modulates immune responses | |
| 应激诱导小蛋白的翻译谱分析揭示了不同信号系统之间意想不到的联系 | Vellappan, S. | N/A | Translational profiling of stress-induced small proteins uncovers an unexpected connection among distinct signaling systems | |
| 元意识、心智游移以及对“默认”外部和内部注意定向的控制 | Christian, I. R. | N/A | Meta-awareness, mind-wandering, and the control of 'default' external and internal orientations of attention | |
| 当小龙虾成为新闻时，标题虽然正确，但仍具误导性。 | Faulkes, Z. | N/A | When crayfish make news, headlines are correct but still misleading | |
| easybio：一个用于使用CellMarker2.0进行单细胞注释的R包 | Wei, C. | N/A | easybio: an R Package for Single-Cell Annotation with CellMarker2.0 | |
| 机械负荷和激素变化对容量超负荷期间离心肥大的贡献：基于逻辑网络模型的贝叶斯分析。 | Bracamonte, J. H. | N/A | Contributions of mechanical loading and hormonal changes to eccentric hypertrophy during volume overload: a Bayesian analysis using logic-based network models. | |
| 一种结构MRI标记物预测了个体在冲动性方面的差异，并将行为变异型额颞叶痴呆患者与匹配的对照组进行了分类。 | Godefroy, V. | N/A | A structural MRI marker predicts individual differences in impulsivity and classifies patients with behavioral-variant frontotemporal dementia from matched controls | |
| XbnAb 群体：304 名对 HIV-1 具有广泛中和抗体活性的人 | Pasin, C. | N/A | The XbnAb Cohort: 304 people with broadly neutralizing antibody activity to HIV-1 | |
| Bcl-xL缺陷的MDCK细胞中肿瘤发生能力降低，确保了流感疫苗生产的安全性。 | Zheng, J. | N/A | Tumorigencity decrease in Bcl-xL deficient MDCK cells ensuring the safety for influenza vaccine production | |
| 复杂群体形态发育过程中基因表达的时空模式 | Cromie, G. A. | N/A | Spatiotemporal Patterns of Gene Expression During Development of a Complex Colony Morphology | |
| rDNA阵列的表观遗传调控与遗传 | Potapova, T. A. | N/A | Epigenetic control and inheritance of rDNA arrays | |
| gsQTL：通过利用其共享变异性将遗传风险变异与基因集相关联 | Bouland, G. A. | N/A | gsQTL: Associating genetic risk variants with gene sets by exploiting their shared variability | |
| 线虫基因组中的调控逻辑与转座元件动态 | Fierst, J. L. | N/A | Regulatory logic and transposable element dynamics in nematode worm genomes | |
| 基于社区的病媒传播疾病昆虫学监测与控制：范围综述 | Eastman, P. | N/A | Community-Based Entomological Surveillance and Control of Vector-Borne Diseases: A Scoping Review | |
| 熟悉的人和地方在类别选择性皮层的视觉影像 | Scrivener, C. L. | N/A | Visual imagery of familiar people and places in category selective cortex | |
| 跨诊断症状领域与儿童多模态成像期间头部运动相关 | Hercules, K. | N/A | Transdiagnostic Symptom Domains are Associated with Head Motion During Multimodal Imaging in Children | |
| 使用重组脱氧核糖核酸酶I治疗抗髓过氧化物酶性肾小球肾炎，通过腺相关病毒基因疗法得到增强 | Cao Le, A. | N/A | Treatment of anti-myeloperoxidase glomerulonephritis using recombinant deoxyribonuclease I is enhanced by adeno-associated virus gene therapy | |
| 在人类星状病毒衣壳刺突上发现三个新的中和抗体表位，并揭示病毒中和的机制性见解 | Lanning, S. | N/A | Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization | |
| 晚发性阿尔茨海默病风险因子iRhom2/RHBDF2是微胶质细胞TREM2蛋白水解的修饰因子 | Jocher, G. | N/A | The late onset Alzheimer's disease risk factor iRhom2/RHBDF2 is a modifier of microglial TREM2 proteolysis | |
| MLPA：一种用于个性化癌症模拟和治疗优化的多尺度数字孪生框架 | Chen, J. Y. | N/A | MLPA: A Multi-scale Digital Twin Framework for Personalized Cancer Simulation and Treatment Optimization | |
| 间充质干细胞衍生的细胞外囊泡可缓解咪喹莫特诱导的小鼠疾病模型中的银屑病症状 | Yi, Y. | N/A | Mesenchymal stem cell-derived extracellular vesicles alleviate imiquimod-induced psoriasis symptoms in a mouse disease model | |
| 对制药行业和研究密集型学术机构的开放获取出版率进行基准测试 | Rees, T. J. | N/A | Benchmarking open access publication rates for the pharmaceutical industry and research-intensive academic institutions | |
| 鸟类命名马拉松：利用众包对英语鸟类名称进行分类 | Morrison, E. S. | N/A | Bird Name-a-thon: Categorizing English bird names using crowdsourcing | |
| TRPV3通道活性有助于皮层神经元在发热期间保持活跃。 | Shen, Y. | N/A | TRPV3 channel activity helps cortical neurons stay active during fever | |
| 文化定向广告牌信息的注意力和保持效果：使用沉浸式虚拟现实的眼动追踪研究 | Jeon, M. | N/A | Attention and Retention Effects of Culturally Targeted Billboard Messages: An Eye-Tracking Study Using Immersive Virtual Reality | |
| 转录组学和多尺度网络分析揭示了心血管疾病的关键驱动因素 | Tumenbayar, B.-I. | N/A | Transcriptomic and multi-scale network analyses reveal key drivers of cardiovascular disease | |
| 深度学习直接从序列预测非正常肽的FAIMS迁移率分布 | McKetney, J. | N/A | Deep Learning Predicts Non-Normal Peptide FAIMS Mobility Distributions Directly from Sequence | |
| SPL家族转录因子DNA结合特异性的多样化和保守性 | Li, M. | N/A | Diversification and conservation of DNA binding specificities of SPL family of transcription factors | |
| 高内涵显微镜与机器学习相结合，揭示了施万细胞中NF1基因型特有的细胞形态特征。 | Tomkinson, J. | N/A | High-content microscopy and machine learning characterize a cell morphology signature of NF1 genotype in Schwann cells | |
| 组织特异性代谢组特征用于减少性二态性的doublesex模型 | Coig, R. | N/A | Tissue-specific metabolomic signatures for a doublesex model of reduced sexual dimorphism | |
| 寨卡病毒NS3驱动形成类似病毒体的结构 | Sultana, T. | N/A | Zika virus NS3 drives the assembly of a viroplasm-like structure | |
| 一种结合纳米纤维和间充质细胞球体的混合生物打印-静电纺丝平台，用于定制化伤口愈合敷料。 | Hosseini, S. A. | N/A | A hybrid bioprinting-electrospinning platform integrating nanofibers and mesenchymal cell spheroids for customizable wound healing dressings | |
| 肌醇六磷酸（InsP6）通过激活HDAC1/3表观遗传轴来维持肠道屏障功能 | Chatterjee, S. | N/A | Inositol Hexaphosphate (InsP6) Activates the HDAC1/3 Epigenetic Axis toMaintain Intestinal Barrier Function | |
| 依赖于细胞周期的S-亚磺酰基蛋白质组学揭示了p21-CDK反馈中的氧化还原开关，该开关调控增殖-衰老决策 | Vorhauser, J. | N/A | Cell cycle-dependent S-sulfenyl proteomics uncover a redox switch in p21-CDK feedback governing the proliferation-senescence decision | |
| 细胞外凝聚物（ECs）是HIV转录和潜伏再激活的内源性调节因子。 | Naushad, W. | N/A | Extracellular condensates (ECs) are endogenous modulators of HIV transcription and latency reactivation | |
| 钙离子诱导的精子停止决定了哺乳动物的胚胎数量。 | Watanabe, H. | N/A | Ca2+-evoked sperm cessation determines embryo number in mammals. | |
| YAP/TAZ信号在由尿囊衍生的细胞中对于胎盘血管化是必需的。 | Gao, S. | N/A | YAP/TAZ signaling in allantois-derived cells is required for placental vascularization | |
| SOX2驱动结直肠癌中的胎儿重编程及可逆休眠 | Baulies, A. | N/A | SOX2 drives fetal reprogramming and reversible dormancy in colorectal cancer | |
| 缺氧应激通过表观基因组和转录程序失调影响胶质瘤相关髓系细胞的功能。 | Dzwigonska, M. | N/A | Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs | |
| 脂肪细胞鞘氨醇激酶1通过调节组蛋白修饰因子来破坏昼夜节律功能 | Anderson, A. | N/A | Adipocyte sphingosine kinase 1 regulates histone modifiers to disrupt circadian function | |
| 空间转录组学揭示了弥漫性大B细胞淋巴瘤中与患者生存相关的免疫细胞生态系统 | Herrero, A. D. | N/A | Spatial transcriptomics unveils immune cellular ecosystems associated with patient survival in diffuse large B-cell lymphoma | |
| 功能性磁共振成像显示，在大鼠大脑进行五天局部高密度θ波爆发刺激（hdTBS）后，脑活动出现区域性变化。 | Li, Q. | N/A | Functional MRI reveals regional changes of brain activity after five days of focal high-density theta burst stimulation (hdTBS) of the rat brain | |
| 南阿拉斯加定居型虎鲸的多样化饮食在空间和时间上不同的觅食群体中发生了变化。 | Myers, H. | N/A | The diverse diet of southern Alaska resident killer whales changes across spatiotemporally distinct foraging aggregations | |
| 澳大利亚维多利亚州中泥盆世豪威特山新种Groenlandaspis（甲胄鱼纲，节甲鱼目）独特的牙齿排列 | Fitzpatrick, A. N. | N/A | Unique dental arrangement in a new species of Groenlandaspis (Placodermi, Arthrodire) from the Middle Devonian of Mount Howitt, Victoria, Australia | |
| 转录因子ZmbZIP75促进玉米籽粒灌浆和籽粒脱水 | Long, T. | N/A | The transcription factor ZmbZIP75 promotes both grain filling and kernel dehydration in maize | |
| TRPC3抑制改善了阿尔茨海默病中的突触功能障碍和记忆缺陷。 | Liao, F.-F. | N/A | TRPC3 suppression ameliorates synaptic dysfunctions and memory deficits in Alzheimer's disease | |
| 纹状体间接通路介导犹豫 | Geramita, M. A. | N/A | Striatal indirect pathway mediates hesitation | |
| 在注意力短暂调节过程中，跨感觉模式的共享皮层下觉醒系统 | Khalaf, A. | N/A | Shared subcortical arousal systems across sensory modalities during transient modulation of attention | |
| 羧基端阻断sortilin结合可增强颗粒蛋白前体基因治疗，这可能成为治疗额颞叶痴呆的一种潜在疗法。 | Kashyap, S. N. | N/A | Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementia | |
| 少样本一致性神经解码（FALCON）基准算法 | Karpowicz, B. M. | N/A | Few-shot Algorithms for Consistent Neural Decoding (FALCON) Benchmark | |
| 在追踪眼球运动期间，对再输入方向上的光动反应的抑制 | Bachtoula, O. | N/A | Suppression of optokinesis in the reafferent direction during pursuit eye movements | |
| 闭合性头部损伤后，由少突胶质细胞前体细胞衍生的反应性星形胶质细胞形成的胶质瘢痕 | Matsuda, H. | N/A | Glial scar formation by reactive astrocytes derived from oligodendrocyte progenitor cells after closed-head injury | |
| 胚胎期暴露于丙戊酸和新烟碱类物质会损害雏鸡端脑中间内侧隔区的发育性GABA转换，并影响局部回路中的长期增强效应。 | Matsushima, T. | N/A | Embryonic exposure to valproic acid and neonicotinoid deteriorates the developmental GABA switch and impairs long-term potentiation in the local circuit of intermediate medial mesopallium of chick telencephalon | |
| 决策中的个体差异塑造了中边缘多巴胺如何调节选择信心和改变心意 | Kocharian, A. | N/A | Individual differences in decision-making shape how mesolimbic dopamine regulates choice confidence and change-of-mind | |
| 高脂和致肥胖饮食对商业可用的小鼠脂肪肝疾病模型大脑体积的影响 | Jiang, L. | N/A | The impact of high-fat and obesogenic diets on brain volume in a commercially available mouse model of fatty liver disease | |
| 果蝇幼虫运动回路的不同组成部分对胚胎关键期扰动的异质性反应 | Krick, N. | N/A | Heterogeneous responses to embryonic critical period perturbations among different components of the Drosophila larval locomotor circuit | |
| 政策复杂性抑制了多巴胺反应 | Gershman, S. J. | N/A | Policy complexity suppresses dopamine responses | |
| 人类睡眠期间，特定特征的预期处理逐渐减弱 | Topalidis, P. I. | N/A | FEATURE-SPECIFIC ANTICIPATORY PROCESSING FADES DURING HUMAN SLEEP | |
| 利用面部表情和互信息自动去除MEG数据中的语音伪影 | Tuomaala, S. | N/A | Automated speech artefact removal from MEG data utilizing facial gestures and mutual information | |
| 一种神经调质觉醒状态的Hopfield网络模型 | Osman, M. A. M. | N/A | A Hopfield network model of neuromodulatory arousal state | |
| 遗传依赖的脑部韧性特征：童年虐待、遗传风险与脑功能之间的相互作用 | Lu, H. | N/A | Genetic-Dependent Brain Signatures of Resilience: Interactions among Childhood Abuse, Genetic Risks and Brain Function | |
| 探索澳式橄榄球运动员功能连接的差异：一项关于默认模式网络的静息态fMRI研究 | Tran, M. | N/A | Exploring Differences in Functional Connectivity in Australian Rules Football Players : A Resting-State fMRI Study on the Default Mode Network | |
| 谷氨酸能调控含miRNA的外泌体前体在皮层神经元中的转运和分泌 | Bertolio, M. | N/A | Glutamatergic regulation of miRNA-containing exosome precursor trafficking and secretion from cortical neurons | |
| 电影引发的脑活动和连接性的遗传性 | Gruskin, D. C. | N/A | Heritability of movie-evoked brain activity and connectivity | |
| 人类和狨猴大脑中的发声处理网络 | Dureux, A. | N/A | Vocal processing networks in the human and marmoset brain | |
| 电压成像揭示了中缝核中与血清素介导的运动活力学习相关的电路计算 | Kawashima, T. | N/A | Voltage imaging reveals circuit computations in the raphe underlying serotonin-mediated motor vigor learning | |
| 视神经挤压不会导致对侧眼的视网膜神经节细胞丢失。 | Schoot Uiterkamp, F. E. | N/A | Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye. | |
| 探究Nogo受体同源物NgR2在建立耳蜗连接中的作用 | Karagulyan, N. | N/A | Probing the role of Nogo receptor homolog NgR2 in setting up cochlear connectivity | |
| 全球性和分隔化的血清素控制对运动适应基础的传感器运动整合的影响 | Haruvi, R. | N/A | Global and compartmentalized serotonergic control of sensorimotor integration underlying motor adaptation | |
| 调节前额叶皮层活动以缓解压力引起的工作记忆缺陷：一项经颅直流电刺激（tDCS）研究 | Roy, S. | N/A | Modulating Prefrontal Cortex Activity to Alleviate Stress-Induced Working Memory Deficits: A Transcranial Direct Current (tDCS) Study | |
| 伏隔核核心翻译组伴随可卡因渴求孵化的变化 | Kawa, A. B. | N/A | Changes in nucleus accumbens core translatome accompanying incubation of cocaine craving | |
| 猕猴大脑中功能和结构网络的年龄相关性改变 | Ouchi, K. | N/A | Age-related alterations in functional and structural networks in the brain in macaque monkeys | |
| 连接组蛋白调控多能造血干细胞和祖细胞在髓系与淋巴系分化中的分支 | Guo, S. | N/A | Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors | |
| Notch和LIM-同源域蛋白Arrowhead通过一种反馈机制相互调节，在果蝇的翅膀和神经发育中发挥作用。 | Singh, J. | N/A | Notch and LIM-homeodomain protein Arrowhead regulate each other in a feedback mechanism to play a role in wing and neuronal development in Drosophila | |
| 隔室的机械耦合驱动小鼠听觉上皮极性和模式的形成 | Prakash, A. | N/A | Mechanical coupling of compartments drives polarity and patterning of mouse auditory epithelium | |
| NR2F2对睾丸间质细胞向胎儿睾丸间质细胞分化的调控：对性别发育差异的见解 | Estermann, M. A. | N/A | NR2F2 regulation of interstitial to fetal Leydig cell differentiation in the testis: insights into differences of sex development | |
| 亚马逊蜻蜓数量预测因子：胸温与生境特征 | Calvao, L. B. | N/A | Thorax temperature and niche characteristics as predictors of abundance of Amazonian Odonata | |
| 北极植物与根际真菌之间的机会性合作选择受环境条件驱动。 | Parisy, B. | N/A | Opportunistic partner choice among arctic plants and root-associated fungi is driven by environmental conditions. | |
| 用于自主接收网络中动物运动建模的粒子算法 | Lavender, E. | N/A | Particle algorithms for animal movement modelling in autonomous receiver networks | |
| 鸣叫声表明长舌蝠的行为类型 | Schabacker, T. | N/A | Vocalisations indicate behavioural type in Glossophagine bats | |
| 基于角色共享的协同群体行为分析：从实验任务到3对3篮球比赛的实际应用作为试点研究 | Ichikawa, J. | N/A | Analysis of coordinated group behavior based on role-sharing: Practical application from an experimental task to a 3-on-3 basketball game as a pilot study | |
| 局部眼用VIAN-c4551抗血管生成肽治疗糖尿病性黄斑水肿：临床前疗效与眼部药代动力学 | Adan-Castro, E. | N/A | Topical Ophthalmic Administration of VIAN-c4551 Antiangiogenic Peptide for Diabetic Macular Edema: Preclinical Efficacy and Ocular Pharmacokinetics | |
| 多巴胺释放位点的突触特化协调高效且精确的神经调节信号传递 | Bulumulla, C. | N/A | Synaptic Specializations at Dopamine Release Sites Orchestrate Efficient and Precise Neuromodulatory Signaling | |
| 重新平衡老年人大脑的抑制系统：平衡学习对GABA能抑制和功能连接的影响 | Liu, X. | N/A | Rebalance the inhibitory system in the elderly brain: Influence of balance learning on GABAergic inhibition and functional connectivity | |
| 位置信息在转录组学识别的神经元类型中驱动不同的特征 | Shainer, I. | N/A | Positional information drives distinct traits in transcriptomically identified neuronal types | |
| 人类运动皮质中全身表征的马赛克 | Deo, D. R. | N/A | A mosaic of whole-body representations in human motor cortex | |
| 定时喂食可改善脆性X综合征小鼠模型的行为表现并减少炎症。 | Wang, H.-B. | N/A | Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome. | |
| 听觉皮层通过选择性多感官增强学习区分视听线索 | Chang, S. | N/A | Auditory Cortex Learns to Discriminate Audiovisual Cues through Selective Multisensory Enhancement | |
| 同侧刺激显示，使用高密度功能性近红外光谱技术，在左侧初级体感皮层上，拇指和肩部的耳穴具有体位分布。 | Okorie, E. | N/A | Ipsilateral stimulation shows somatotopy of thumb and shoulder auricular points on the left primary somatosensory cortex using high-density fNIRS | |
| 建立一个优化的、自动化的全脑神经元活动探测工作流程。 | CABRERA, S. | N/A | Establishment of an optimized and automated workflow for whole brain probing of neuronal activity. | |
| 操纵注意力优先级在人类视觉皮层中产生了记忆与感觉表征之间的权衡 | Rademaker, R. L. | N/A | Manipulating attentional priority creates a trade-off between memory and sensory representations in human visual cortex | |
| 微管在肌肉发育过程中协调线粒体运输与肌纤维形态发生 | Avellaneda, J. | N/A | Microtubules coordinate mitochondria transport with myofibril morphogenesis during muscle development | |
| 细菌在动态珊瑚宿主上共存，存在竞争-定殖权衡 | Gibbs, T. | N/A | Coexistence of bacteria with a competition-colonization tradeoff on a dynamic coral host | |
| 面向大规模博物馆基因组学项目：一种经济高效且高通量的方法，用于从博物馆昆虫标本中获取历史DNA | Holmquist, A. J. | N/A | Towards large-scale museomics projects: a cost-effective and high-throughput extraction method for obtaining historical DNA from museum insect specimens | |
| 高速4D荧光光场断层成像技术对自由活动生物体的整体成像 | Zhou, K. C. | N/A | High-speed 4D fluorescence light field tomography of whole freely moving organisms | |
| 纤维状和无定形胶原蛋白相互渗透的网络促进了细胞的扩散和凝胶的稳定性。 | Brunel, L. G. | N/A | Interpenetrating networks of fibrillar and amorphous collagen promote cell spreading and hydrogel stability | |
| PEARL：重组乳酸菌蛋白洗脱海藻酸盐 | Tadimarri, V. S. | N/A | PEARL: Protein Eluting Alginate with Recombinant Lactobacilli | |
| 最优传输通过基因速度估计揭示动态基因调控网络 | Zhao, W. | N/A | Optimal transport reveals dynamic gene regulatory networks via gene velocity estimation | |
| 灵活且强大的高倍数组织图像细胞类型注释 | Sun, H. | N/A | Flexible and robust cell type annotation for highly multiplexed tissue images | |
| 脑癌衍生因子对原代人脑周细胞的筛选活性 | McCullough, S. J. | N/A | Screening activity of brain cancer-derived factors on primary human brain pericytes | |
| 在伊比利亚半岛上，遗传结构化的拟南芥（Arabidopsis thaliana）中，根分泌物成分的自然变异 | Subrahmaniam, H. J. | N/A | Natural variation in root exudate composition in the genetically structured Arabidopsis thaliana in the Iberian Peninsula | |
| 模型显示，在接受奈玛特韦-利托那韦治疗后，SARS-CoV-2的反弹是由目标细胞的保留与不完全的病毒清除共同驱动的。 | Phan, T. | N/A | Modeling suggests SARS-CoV-2 rebound after nirmatrelvir-ritonavir treatment is driven by target cell preservation coupled with incomplete viral clearance | |
| 空间微环境调节果蝇幼虫脂肪体中的免疫应答动态 | Schlomann, B. H. | N/A | Spatial microenvironments tune immune response dynamics in the Drosophila larval fat body | |
| 致病相关真菌辅助染色体中的广泛染色体内重复 | Dijkstra, J. | N/A | Extensive intrachromosomal duplications in a virulence-associated fungal accessory chromosome | |
| 塑料圈：塑料时代的海洋真菌群落 | Kirstein, I. | N/A | The Plastisphere: Marine fungi communities in the plastics age | |
| 评估从烧焦土壤中分离嗜火细菌和真菌的最佳实践 | Enright, D. J. | N/A | Evaluating Best Practices for Isolating Pyrophilous Bacteria and Fungi from Burned Soil | |
| 内共生体Rickettsiella viridis增加了Diuraphis noxia的毒性，但降低了有翅个体的频率。 | Gu, X. | N/A | The endosymbiont Rickettsiella viridis increases the virulence of Diuraphis noxia but reduces alate frequency | |
| DNA损伤应答与RNA聚合酶II调节因子Def1在细胞质中具有转录后功能 | Akinniyi, O. T. | N/A | The DNA damage response and RNA Polymerase II regulator Def1 has posttranscriptional functions in the cytoplasm | |
| 扩张显微镜技术能够对血小板聚集物的结构组织进行定量表征。 | Faulkner, E. L. | N/A | Expansion microscopy allows quantitative characterisation of structural organisation of platelet aggregates | |
| 不同的H3K9me3异染色质维持动态调控多能细胞中不同的基因程序和重复序列 | Zhang, J. | N/A | Distinct H3K9me3 heterochromatin maintenance dynamics govern different gene programs and repeats in pluripotent cells | |
| L1CAM SAX-7是一种Erk信号通路的拮抗调制剂。 | Moseley-Alldredge, M. | N/A | The L1CAM SAX-7 is an antagonistic modulator of Erk signaling | |
| 间期染色体构象由特定的折叠程序决定，这些程序通过有丝分裂染色体或通过细胞质遗传。 | Schooley, A. | N/A | Interphase chromosome conformation is specified by distinct folding programs inherited via mitotic chromosomes or through the cytoplasm | |
| DeOri 10.0：实验鉴定真核生物复制起源的更新数据库 | Zeng, Y.-H. | N/A | DeOri 10.0: An Updated Database of Experimentally Identified Eukaryotic Replication Origins | |
| 使用voomCLR评估单细胞研究中的差异细胞组成 | Takele Assefa, A. | N/A | Assessing differential cell composition in single-cell studies using voomCLR | |
| 有丝分裂到G1期过渡过程中微隔室形成的动力学 | Goel, V. Y. | N/A | Dynamics of microcompartment formation at the mitosis-to-G1 transition | |
| 彩虹蟒（Epicrates cenchria）收藏中多焦点皮肤肿瘤血管增生与蟒蛇包涵体病的关系 | Broering Ferreira, A. | N/A | Multifocal cutaneous neoplastic vascular proliferations in a rainbow boa (Epicrates cenchria) collection with boid inclusion body disease | |
| 不同培养基中阴道毛滴虫的生长分析：利用大型语言模型（LLMs）预测和优化体外生长条件 | Ferguson, S. L. | N/A | Growth Analysis of Trichomonas vaginalis in Different Culture Media: Leveraging Large Language Models (LLMs) to Predict and Optimize In Vitro Growth Conditions | |
| 无染色傅里叶叠层显微术与传统组织病理学光学显微术在肾小球膜性肾病中的比较分析 | Valentino, M. | N/A | Comparative Analysis of Stain-Free Fourier Ptychographic Microscopy and Traditional Histopathological Light Microscopy in Renal Membranous Nephropathy | |
| 手术性甲状软骨复位对下颌前移和上气道塌陷性的影响 | Tannous, H. J. | N/A | Surgical hyoid bone repositioning effects on mandibular advancement and upper airway collapsibility | |
| 在植物细胞器中利用工程化的合成P型PPR编辑因子实现从头RNA碱基编辑 | Mathieu, S. | N/A | De novo RNA base editing in plant organelles with engineered synthetic P-type PPR editing factors | |
| 模块化纳米支架生物催化用于卓越的PET解聚和增值 | Zhang, Y. | N/A | Modular Nano-Scaffold Biocatalysis for Superior PET Depolymerization and Valorization | |
| 解码溃疡性结肠炎中的细胞因子网络：识别致病机制与治疗靶点 | Olbei, M. L. | N/A | Decoding Cytokine Networks in Ulcerative Colitis to Identify Pathogenic Mechanisms and Therapeutic Targets | |
| 通过ParB样BisD-CTP DNA夹钳在低频转移能力发育中实现的长距离基因激活 | Antar, H. | N/A | Orchestrated long-distance gene activation by a ParB-like BisD-CTP DNA clamp in low-frequency transfer competence development in Pseudomonas putida | |
| 微生物群与气候：与生物气候相关的斑腿泛树蛙（Anura: Rhacophoridae）皮肤微生物多样性及群落功能 | Meegaskumbura, M. | N/A | Microbiome and climate: Skin microbial diversity and community functions of Polypedates megacephalus (Anura: Rhacophoridae) associated with bioclimate | |
| 利用蚂蚁共生体制作酸奶揭示了用于食品发酵的细菌、酸和酶 | Sinotte, V. M. | N/A | Making yogurt with the ant holobiont uncovers bacteria, acids, and enzymes for food fermentation | |
| 立克次体立克次体（Rickettsia rickettsii）编码一种分泌性脂酶，该脂酶有助于其在宿主细胞胞质内的定殖。 | Sadik, M. | N/A | Rickettsia rickettsii encodes a secretory lipase that facilitates intracytosolic colonization in host cells. | |
| 结构引导的流感刺突纳米生物囊疫苗组装提供了泛H1鼻内保护 | Myers, M. L. | N/A | Structure-guided assembly of an influenza spike nanobicelle vaccine provides pan H1 intranasal protection | |
| 活性细菌SIR2-STAND丝状体的冷冻电镜结构 | Wang, Y. | N/A | Cryo-EM Structure of an Active Bacterial SIR2-STAND Filament | |
| 利用深度学习映射嗅觉受体与感知之间的组合编码 | Chithrananda, S. | N/A | Mapping the combinatorial coding between olfactory receptors and perception with deep learning | |
| 利用分子模拟和图神经网络探索潜在的肠道产甲烷抑制剂 | Aryee, R. | N/A | Exploring putative enteric methanogenesis inhibitors using molecular simulations and a graph neural network | |
| 基于探针捕获富集的全球病原体、呼吸道合胞病毒（RSV）和人诺如病毒（HuNoV）的完整基因组特征分析 | Doddapaneni, H. | N/A | Complete Genomic Characterization of Global Pathogens, Respiratory Syncytial Virus (RSV), and Human Norovirus (HuNoV) Using Probe-based Capture Enrichment. | |
| 针对Pannexin 1的萘啶酮类化合物用于炎症性肠病管理 | Hsueh, W.-Y. | N/A | Novel naphthyridones targeting Pannexin 1 for colitis management | |
| 在活细胞中进行RNA二级结构集合图谱绘制，识别出保守的RNA调控开关和温度计 | Borovska, I. | N/A | RNA secondary structure ensemble mapping in a living cell identifies conserved RNA regulatory switches and thermometers | |
| RalB 解偶联的外泌体介导内皮细胞魏贝尔-帕拉德小体的胞吐作用 | Yang, M. | N/A | RalB uncoupled exocyst mediates endothelial Weibel-Palade body exocytosis | |
| 新型3D培养装置在人网膜脂肪细胞和手术衍生的巨噬细胞中的应用 | Shimoji, M. | N/A | Application of novel 3D culture device for human omental adipocytes and macrophages derived from surgery | |
| L-氨基酸氧化酶对细胞破坏的功能分析与综合机制 | Prak, K. | N/A | Functional analyses and integrated mechanisms of cellular destruction by L-amino acid oxidase | |
| 结构重复检测器：通过显微镜技术实现分子复合物的多尺度定量映射 | Mendes, A. | N/A | Structural Repetition Detector: multi-scale quantitative mapping of molecular complexes through microscopy | |
| 细胞质分裂沟的形成需要微管和Plk1的协同作用。 | Day, C. A. | N/A | Commitment to cytokinetic furrowing requires the coordinate activity of microtubules and Plk1 | |
| MEK1/2激酶与c-Myc:MAX协同作用，防止多梳蛋白对人类多能干细胞中TERT的抑制 | Kotian, S. T. | N/A | MEK1/2 kinases cooperate with c-Myc:MAX to prevent polycomb repression of TERT in human pluripotent stem cells | |
| 跨组织协调的SLC核苷转运体在秀丽隐杆线虫生殖调控中的作用 | Guan, Y. | N/A | Cross-Tissue Coordination between SLC Nucleoside Transporters Regulates Reproduction in Caenorhabditis elegans | |
| 阳光照射的皮肤中普遍存在调控突变微克隆的诱导 | Menon, V. | N/A | Pervasive Induction of Regulatory Mutation Microclones in Sun-exposed Skin | |
| 一种利用智能手机照片进行主成分分析识别牛奶掺假和Pb(II)污染情况的可能方法 | Chandra, A. C. | N/A | A Potential Method for Identifying Milk Adulteration and Pb(II) Contamination Scenarios Using Principal Component Analysis from Smartphone Photographs | |
| PP2A:B55-Eya3和PP2A:B55-p107的冷冻电镜结构定义了PP2A:B55底物招募 | Padi, S. K. | N/A | Cryo-EM structures of PP2A:B55-Eya3 and PP2A:B55-p107 define PP2A:B55 substrate recruitment | |
| MAPK/ERK信号通路在胶质瘤中调控干扰素反应、T细胞招募，增强肿瘤-小胶质细胞间的相互作用，并推动免疫检查点阻断疗法的疗效。 | Kim, K.-S. | N/A | MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, enhances tumor-microglia crosstalk, and drives immune checkpoint blockade efficacy. | |
| # BioRxiv 2024-09-15 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 进化上多样的穴样内陷蛋白共享一个围绕两亲性圆盘构建的共同结构框架。 | Han, B. | N/A | Evolutionarily diverse caveolins share a common structural framework built around amphipathic discs | |
| 综合确定与亨廷顿病相关的突变型亨廷顿蛋白外显子1纤维的原子结构 | Bagherpoor Helabad, M. | N/A | Integrative determination of the atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington's disease | |
| 人类病原体肺炎支原体和生殖支原体粘附复合体的动力学 | Kawamoto, A. | N/A | Dynamics of the adhesion complex of the human pathogens Mycoplasma pneumoniae and Mycoplasma genitalium | |
| 细胞丝状体在细菌聚集和集群-集群组装中的作用 | Charlton, S. G. V. | N/A | The role of cellular filamentation in bacterialaggregation and cluster-cluster assembly | |
| 使用线性图像解码器和非线性噪声抑制从人类大脑活动中重建的无语义视觉图像 | Li, Q. | N/A | Visual Image Reconstructed Without Semantics from Human Brain Activity Using Linear Image Decoders and Nonlinear Noise Suppression | |
| 工程化酵母细胞模拟CD19+癌症，以控制CAR T细胞的激活 | Deichmann, M. | N/A | Engineered yeast cells simulating CD19+ cancers to control CAR T cell activation | |
| 通过竞争性蛋白质二聚化网络进行计算的原理 | Parres-Gold, J. | N/A | Principles of Computation by Competitive Protein Dimerization Networks | |
| 三种RING蛋白的不同且相互依赖的功能调控哺乳动物减数分裂中的重组过程。 | Ito, M. | N/A | Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis | |
| 普罗克拉斯提斯图（Prokrustean Graph）：一种用于快速k-mer大小分析的子串索引 | Park, A. | N/A | Prokrustean Graph: A substring index for rapid k-mer size analysis | |
| 一种动态系统方法用于最佳觅食 | Chaturvedi, S. | N/A | A Dynamical Systems Approach to Optimal Foraging | |
| 表征差异成分分析（ReDisCA） | Ossadtchi, A. | N/A | Representational dissimilarity component analysis (ReDisCA) | |
| 鉴定调控腭发育的新基因 | Bhaskar, A. | N/A | Identification of novel genes regulating the development of the palate | |
| CD4+ T细胞在急性水缺乏型干眼模型中驱动角膜神经损伤，但并不引起上皮病变 | Vereertbrugghen, A. | N/A | CD4+ T cells drive corneal nerve damage but not epitheliopathy in an acute aqueous-deficient dry eye model | |
| 改进六倍体小麦的基因组选择：亚基因组加性和上位性模型 | Tessele, A. | N/A | Improving genomic selection in hexaploid wheat with sub-genome additive and epistatic models | |
| 前庭眼动反射的成熟并不依赖于感觉输入 | Leary, P. | N/A | Sensation is Dispensable for the Maturation of the Vestibulo-ocular Reflex | |
| PGE2合成/反应通路的破坏可抑制程序性细胞死亡-1（Pd-1）缺陷的高脂血症小鼠的动脉粥样硬化形成。 | Ricciotti, E. | N/A | Disruption of the PGE2 synthesis / response pathway restrains atherogenesis in programmed cell death-1 (Pd-1) deficient hyperlipidemic mice | |
| 延长酶和去饱和酶编码基因的表达塑造了蜜蜂表皮碳氢化合物的特征 | Rodriguez-Leon, D. S. | N/A | Expression of elongase- and desaturase-encoding genes shapes the cuticular hydrocarbon profiles of honey bees | |
| GBA1 突变改变了神经元的放电和结构，调节了多巴胺神经元中的 VGLUT2 和 CRYAB | Rodriguez-Traver, E. | N/A | GBA1 mutations alter neuronal firing and structure, regulating VGLUT2 and CRYAB in dopamine neurons | |
| 神经肽催产素通过调节血流动力学和通透性，促进其从大脑到外周的摄取。 | Rajamannar, P. | N/A | Neuropeptide oxytocin facilitates its own brain-to-periphery uptake by regulating blood flow dynamics and permeability | |
| 睡眠期间，脑淋巴系统清除功能得到增强。 | Kroesbergen, E. | N/A | Glymphatic clearance is enhanced during sleep | |
| SCRATCH：一种可编程、开源硬件的台式机器人，能够自动刮擦培养的组织，以研究细胞迁移、愈合和组织塑形。 | Lin, Y. | N/A | SCRATCH: A programmable, open-hardware, benchtop robot that automatically scratches cultured tissues to investigate cell migration, healing, and tissue sculpting. | |
| 不那么自私：可移动元件助力适应气候变化 | Potapenko, E. V. | N/A | Not so selfish: transposable elements fuel adaptation to climate change | |
| 线粒体过度活跃和活性氧驱动对黄热病病毒-17D减毒活疫苗的先天免疫反应 | Muccilli, S. G. | N/A | Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine | |
| 鉴定影响CRISPR相关转座酶的蛋白质以增强基因组编辑 | Song, L. | N/A | Identification of Proteins Influencing CRISPR-Associated Transposases for Enhanced Genome Editing | |
| 有丝分裂驱动蛋白-5是轴突生长的动态制动器 | Lu, W. | N/A | 'Mitotic' kinesin-5 is a dynamic brake for axonal growth | |
| 喷墨打印的石墨烯多电极阵列：体外心脏电生理学的可及平台 | Lumpuy-Castillo, J. | N/A | Inkjet-printed graphene multielectrode arrays: an accessible platform for in vitro cardiac electrophysiology | |
| 番茄和茄子幼苗茎部软化和半透明形态学特征因感染拉尔氏假单胞菌F1C1所致 | Bhuyan, S. | N/A | Morphology of softening and translucency in the stems of tomato and eggplant seedlings due to infection by Ralstonia pseudosolanacearum F1C1 | |
| 通过明胶-弹性纤维增强水凝胶进行阴道组织工程 | Zambuto, S. G. | N/A | Vaginal Tissue Engineering via Gelatin-Elastin Fiber-Reinforced Hydrogels | |
| ARHGEF3调节毛囊形态发生 | Kalyanakrishnan, K. | N/A | ARHGEF3 Regulates Hair Follicle Morphogenesis | |
| 应激诱导小蛋白的翻译组学分析揭示了不同信号系统之间出乎意料的联系 | Vellappan, S. | N/A | Translational profiling of stress-induced small proteins uncovers an unexpected connection among distinct signaling systems | |
| 微生物群通过保护卵巢储备来延长生殖寿命 | Munyoki, S. K. | N/A | The microbiota extends the reproductive lifespan by safeguarding the ovarian reserve | |
| 人类胎儿期前颅窝形态学评估及其临床意义。 | Derkowski, W. | N/A | Morphometric evaluation of the anterior cranial fossa during the prenatal stage in humans and its clinical implications. | |
| 长末端重复序列逆转录转座子通过增强子捕获产生类似病毒的颗粒，导致发育中的肢体表型 | Glaser, J. | N/A | Enhancer adoption by an LTR retrotransposongenerates viral-like particles causingdevelopmental limb phenotypes | |
| 适度激活线粒体未折叠蛋白反应可延长寿命，但不会增加对压力的抵抗力。 | Di Pede, A. | N/A | Mild activation of the mitochondrial unfolded protein response increases lifespan without increasing resistance to stress | |
| 模拟有蹄类动物的夜间协调节律 | Ukrow, J. | N/A | Modelling coordinated nocturnal rhythms in ungulates | |
| 蓝斑的α-2受体激动作用会损害由负向预测误差驱动的学习过程。 | Lui, S. K. C. | N/A | Alpha-2 agonism of the locus coeruleus impairs learning driven by negative prediction error | |
| 使用模糊聚类对分级动物发声进行无监督分类 | Benti, B. | N/A | Unsupervised classification of graded animal vocalisations using fuzzy clustering | |
| 利用人类测序、斑马鱼筛选和蛋白质结合微阵列技术鉴定眼部先天性颅神经运动神经元疾病的基因 | Jurgens, J. A. | N/A | Gene identification for ocular congenital cranial motor neuron disorders using human sequencing, zebrafish screening, and protein binding microarrays | |
| 老年人中的优越感错觉：楔前叶的体积和功能连接性 | Shidei, Y. | N/A | Superiority illusion in older adults: volume and functional connectivity of the precuneus | |
| 前额叶皮层和循环神经网络中反转学习的神经动力学 | Kim, C. M. | N/A | Neural dynamics of reversal learningin the prefrontal cortex and recurrent neural networks | |
| Cav3.1是POMC神经元中的亮氨酸传感器，介导食欲抑制和体重减轻。 | Tsang, A. H. | N/A | Cav3.1 is a leucine sensor in POMC neurons mediating appetite suppression and weight loss | |
| 数据驱动的1H-MRS基集成分的确定 | Davies-Jenkins, C. W. | N/A | Data-driven determination of 1H-MRS basis set composition | |
| 目标记忆再激活引发了与纺锤波相关的时间压缩再激活 | Abdellahi, M. E. A. | N/A | Targeted memory reactivation elicits temporally compressed reactivation linked to spindles | |
| 元意识、心智游移以及对“默认”外部和内部注意定向的控制 | Christian, I. R. | N/A | Meta-awareness, mind-wandering, and the control of 'default' external and internal orientations of attention | |
| 在小脑的Crus I和II区域，浦肯野细胞在猴子学习基于强化的视动关联任务时，既编码视觉刺激，也编码即将做出的选择。 | Ipata, A. | N/A | Purkinje cells in Crus I and II encode the visual stimulus and the impending choice as monkeys learn a reinforcement based visuomotor association task | |
| 用于分类神经元形态的深度学习：结合拓扑数据分析与图神经网络 | Kanari, L. | N/A | Deep learning for classifying neuronal morphologies: combining topological data analysis and graph neural networks | |
| 超越脑电图起始瞬变：对模式眩光刺激的恒定呈现和消失的超兴奋性的敏感化和习惯化 | Jefferis, T. | N/A | Beyond EEG Onset Transients: Sensitisation and Habituation of Hyper-excitation to Constant Presentation and Offset ofPattern-Glare Stimuli | |
| 通过放电率适应产生交替θ波扫描的系统模型 | Ji, Z. | N/A | A systems model of alternating theta sweeps via firing rate adaptation | |
| 石榴籽油通过Keap1/Nrf2/NQO1通路对大鼠皮质短暂性大脑中动脉闭塞的预防作用 | Li, D. | N/A | Preventive Effects of Pomegranate Seed Oil on Transient Middle Cerebral Artery Occlusion via the Keap1/Nrf2/NQO1 Pathway in the rats Cortex | |
| 小胶质细胞中的BRD4表达支持T细胞招募进入中枢神经系统，并加剧实验性自身免疫性脑脊髓炎（EAE）。 | Dey, A. | N/A | BRD4 expression in microglia supports recruitment of T cells into the CNS and exacerbates EAE | |
| 反馈在应对渐进和突发视觉-本体感觉线索冲突中的作用 | Babu, R. | N/A | The role of feedback in responding to gradual and abrupt visuo-proprioceptive cue conflict | |
| 用于视觉、眼动追踪和脑电图研究的高速OLED显示器，以实现精确刺激 | Dimigen, O. | N/A | A high-speed OLED monitor for precise stimulation in vision, eye-tracking, and EEG research | |
| 发育过程中GABA水平降低导致斑马鱼幼体顶盖的连接性增加 | Liu, Y. | N/A | Decreased GABA levels during development result in increased connectivity in the larval zebrafish tectum | |
| 昼夜节律的高度明显性与男性的负面情绪特质以及对惩罚相关信息增强的神经处理有关。 | Scislewska, P. | N/A | High distinctness of circadian rhythm is related to negative emotionality and enhanced neural processing of punishment-related information in men | |
| 前扣带回（ACC）印记神经元的早期内在可塑性决定了记忆的形成和精确性 | Hadzibegovic, S. | N/A | Early intrinsic plasticity of ACC engram neurons defines memory formation and precision | |
| 经颅电刺激可调节前庭系统 | Laakso, I. | N/A | Transcranial electrical brain stimulation modulates the vestibular system | |
| AAV介导的proneural因子表达在体内刺激成年Müller胶质细胞的神经发生。 | Pavlou, M. | N/A | AAV-mediated expression of proneural factors stimulates neurogenesis from adult Müller glia in vivo. | |
| 不同行为相关的刺激在嗅觉系统中引发不同形式的适应 | Nikolaev, A. | N/A | Different behaviourally relevant stimuli evoke different forms of adaptation in the olfactory system | |
| 在拉福拉病（一种严重的进行性肌阵挛性癫痫）的小鼠模型中，谷氨酸能和GABA能信号通路中的胶质细胞改变 | Viana, R. | N/A | Glial alterations in the glutamatergic and GABAergic signaling pathways in a mouse model of Lafora disease, a severe form of progressive myoclonus epilepsy | |
| 相关和反相关双眼视差调节人脑视觉皮层中的GABA+和谷氨酸/谷氨酰胺浓度 | Matuszewski, J. | N/A | Correlated and Anticorrelated Binocular Disparity Modulate GABA+ and Glutamate/glutamine Concentrations in the Human Visual Cortex | |
| 慢性中风中异常μ节律状态相关的皮层和皮层脊髓反应 | Wischnewski, M. | N/A | Abnormal mu rhythm state-related cortical and corticospinal responses in chronic stroke | |
| 通过放电率适应动态调制海马回放序列 | Ji, Z. | N/A | Dynamical Modulation of Hippocampal Replay Sequences through Firing Rate Adaptation | |
| 在帕金森病中，人类皮层-基底神经节网络在运动序列启动期间的学习相关振荡动力学 | Presbrey, K. N. | N/A | Learning-related oscillatory dynamics in the human cortico-basal ganglia network during motor sequence initiation in Parkinson's Disease | |
| 病毒介导的传出抑制增强可减少野生型小鼠耳蜗的声损伤。 | Slika, E. | N/A | Virally-Mediated Enhancement of Efferent Inhibition Reduces Acoustic Trauma in Wild Type Murine Cochleas. | |
| Track-A-Worm 2.0：用于量化秀丽隐杆线虫运动、弯曲、睡眠及动作电位特性的软件套件 | Vedantham, K. | N/A | Track-A-Worm 2.0: A Software Suite for Quantifying Properties of C. elegans Locomotion, Bending, Sleep, and Action Potentials | |
| 量化生物物理因素对通过残余功能网络塑造大脑交流的影响 | Nakuci, J. | N/A | Quantifying the influence of biophysical factors in shaping brain communication through remnant functional networks | |
| 重复性磁刺激作用于运动皮层，通过抑制皮层内抑制的上调，损害平衡任务的巩固。 | Egger, S. | N/A | Repetitive magnetic stimuli over the motor cortex impair consolidation of a balance task by suppressing up-regulation of intracortical inhibition | |
| 皮质内注射免疫检查点抑制剂促进单核细胞/巨噬细胞浸润，并恢复AD小鼠模型中的小胶质细胞功能和神经元活动 | Park, T. | N/A | Intracortical injection of immune checkpoint inhibitor promotes monocyte/macrophage infiltration and restores microglial function and neuronal activity in an AD mouse model | |
| 用于离体和在体活细胞成像的等渗和微创光学透明介质 | Inagaki, S. | N/A | Isotonic and minimally invasive optical clearing media for live cell imaging ex vivo and in vivo | |
| 横断面脑龄评估在预测未来脑变化方面存在局限性。 | Korbmacher, M. | N/A | Cross-sectional brain age assessments are limited in predicting future brain change | |
| SMN缺乏在脊髓性肌肉萎缩症的SMN{triangleup}7小鼠模型中，引发了早期非萎缩性肌病，导致骨骼肌纤维的收缩和兴奋耦合机制发生改变。 | Berciano, M. T. | N/A | SMN deficiency induces an early non-atrophic myopathy with alterations in the contractile and excitatory coupling machinery of skeletal myofibers in the SMN{triangleup}7 mouse model of spinal muscular atrophy | |
| 在猕猴下丘中视觉诱发活动与听觉反应的变量调制 | Schmehl, M. N. | N/A | Visually-evoked activity and variable modulation of auditory responses in the macaque inferior colliculus | |
| 在谷氨酸能神经元中失活Ndufs4揭示了Leigh综合征小鼠模型中吞咽呼吸失调 | Huff, A. D. | N/A | Ndufs4 inactivation in glutamatergic neurons reveals swallow-breathing discoordination in a mouse model of Leigh Syndrome | |
| 人类NLRP3炎症小体激活导致在微管组织中心形成凝聚物 | Wang, J. | N/A | Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center | |
| 秀丽隐杆线虫中的体细胞转甲状腺素相关蛋白通过维持精子完整性和适时排卵来调控生殖寿命 | Wu, T. | N/A | Somatic Transthyretin-Related Proteins in C. elegans Govern Reproductive Longevity by Sustaining Sperm Integrity and Timely Ovulation | |
| 从胚胎鼻干细胞重建功能性嗅觉感觉组织 | Suzuki, K. | N/A | Reconstruction of functional olfactory sensory tissue from embryonic nasal stem cells | |
| 果蝇雌激素相关受体促进幼虫脂肪体内的甘油三酯储存 | Fasteen, T. D. | N/A | The Drosophila Estrogen-Related Receptor promotes triglyceride storage within the larval fat body | |
| 普遍存在的有方向性选择发现，实现了古DNA揭示人类适应性的承诺。 | Akbari, A. | N/A | Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation | |
| 肌梭为运动序列提供灵活的感觉反馈。 | Olson, W. P. | N/A | Muscle spindles provide flexible sensory feedback for movement sequences | |
| 基于正念的神经反馈：对EEG和fMRI研究的系统综述 | Treves, I. N. | N/A | Mindfulness-based Neurofeedback: A Systematic Review of EEG and fMRI studies | |
| 在自发活动期间，神经血管脉冲响应函数（IRF）在不同皮质区域差异性地反映了内在的神经调节作用。 | Rauscher, B. C. | N/A | Neurovascular Impulse Response Function (IRF) during spontaneous activity differentially reflects intrinsic neuromodulation across cortical regions | |
| 在记忆回忆和视觉感知过程中，对手的视觉空间编码结构在脑内侧顶叶皮层中进行反应。 | Scrivener, C. L. | N/A | Opponent visuospatial coding structures responses during memory recall and visual perception in medial parietal cortex | |
| 自由生活的旋毛虫（Strongyloides）物种生命阶段的温度感觉行为有助于其在热带环境中的寄生。 | Gregory, B. T. | N/A | Thermosensory behaviors of the free-living life stages of Strongyloides species support parasitism in tropical environments | |
| 自由生活的旋毛虫生命阶段的温度感应行为有助于其在热带环境中的寄生。 | Gregory, B. T. | N/A | Thermosensory behaviors of the free-living life stages of Strongyloides species support parasitism in tropical environments | |
| 根据过去的和当前的照顾经历，对依恋模式叙事的神经和言语反应有所不同。 | Lee, C. S. | N/A | Neural and verbal responses to attachment-schema narratives differ based on past and current caregiving experiences | |
| 杏仁核对不确定性下动态模型仲裁的贡献 | Woo, J. H. | N/A | Contribution of amygdala to dynamic model arbitration under uncertainty | |
| 结合转录组学、连接性和活性分析，利用高度放大的多重原位杂交技术（hamFISH）对内侧杏仁核进行研究 | Edwards, M. D. | N/A | Combined transcriptomic, connectivity, and activity profiling of the medial amygdala using highly amplified multiplexed in situ hybridization (hamFISH) | |
| 海马结构中以自我为中心的社会知识的锚定与调整 | Rodriguez Aramendia, M. | N/A | Egocentric anchoring-and-adjustment of social knowledge in the hippocampal formation | |
| SNc多巴胺能神经元中PKA-RIIβ水平的年龄相关性下降是PD发病的基础 | Zhao, Y. | N/A | Age-related decline of PKA-RIIβ level in SNc dopaminergic neurons underlies PD pathogenesis | |
| 内源性G蛋白信号调节因子14（RGS14）抑制雌性小鼠中可卡因诱导的情感动机行为 | Bramlett, S. N. | N/A | Endogenous Regulator of G protein Signaling 14 (RGS14) suppresses cocaine-induced emotionally motivated behaviors in female mice | |
| 使用物理信息神经网络建模感觉运动处理 | Perez Rotondo, A. | N/A | Modeling Sensorimotor Processing with Physics-Informed Neural Networks | |
| 大麻和精神病对多巴胺系统的汇聚效应：一项针对大麻使用障碍和首发精神分裂症的纵向神经黑色素敏感MRI研究。 | Ahrens, J. | N/A | Converging effects of cannabis and psychosis on the dopamine system: A longitudinal neuromelanin-sensitive MRI study in cannabis use disorder and first episode schizophrenia. | |
| 早期生活中接触多氯联苯的认知影响：涉及大脑多巴胺系统的性别特异性行为、激素和神经分子机制。 | Hilz, E. N. | N/A | Cognitive effects of early life exposure to PCBs: Sex-specific behavioral, hormonal and neuromolecular mechanisms involving the brain dopamine system. | |
| 实践重塑了任务特化表征的几何结构与动态特性 | Kikumoto, A. | N/A | Practice Reshapes the Geometry and Dynamics of Task-tailored Representations | |
| 海马相位依赖性刺激：一种计算建模方法 | Lee, H.-P. | N/A | Phase-Dependent Stimulation of the Hippocampus: A Computational Modeling Approach | |
| 低温电子显微镜下的磷脂酶Cϵ结构揭示了N端结构域及其在活性中的作用 | Samassekou, K. | N/A | Cryo-EM Structure of Phospholipase Cϵ Defines N-terminal Domains and their Roles in Activity | |
| 人类大脑中的注意力信息传递 | Boroujeni, K. B. | N/A | Attentional Information Routing in The Human Brain | |
| 脑干回路控制小鼠类似咳嗽的气道防御行为 | Xu, X. | N/A | A brainstem circuit controls cough-like airway defensive behaviors in mice | |
| 人类气道上皮细胞的单细胞分析揭示了细胞类型特异性对曲霉菌和球孢子菌的反应 | Harding, A. T. | N/A | Single-cell analysis of human airway epithelium identifies cell type-specific responses to Aspergillus and Coccidioides | |
| 一种新型快速宿主细胞进入途径决定金黄色葡萄球菌的胞内命运 | Rühling, M. | N/A | A Novel Rapid Host Cell Entry Pathway Determines Intracellular Fate of Staphylococcus aureus | |
| 小胶质细胞特异性NF-κB信号传导是朊病毒诱导的胶质炎症和神经元损失的关键调节因子。 | Hay, A. J. D. | N/A | Microglia-specific NF-κB signaling is a critical regulator of prion-induced glial inflammation and neuronal loss | |
| 评估咸海残留湖泊系统：盐度波动对浮游植物群落的影响 | Malashenkov, D. V. | N/A | Assessing Aral Sea residual lake system: impact of fluctuating salinity on phytoplankton communities | |
| 逃离药物偏见陷阱：利用去偏设计提升药物-靶点相互作用预测的可解释性与泛化能力 | Zhang, P.-D. | N/A | Escaping the drug-bias trap: using debiasing design to improve interpretability and generalization of drug-target interaction prediction | |
| TopBP1生物分子凝聚物：晚期结直肠癌的新治疗靶点。 | Morano, L. | N/A | TopBP1 biomolecular condensates: a new therapeutic target in advanced-stage colorectal cancer. | |
| MITF在胃肠道间质瘤中的靶点：对自噬和细胞外囊泡分泌的启示 | Proano-Perez, E. | N/A | MITF Targets in Gastrointestinal Stromal Tumors: Implication in Autophagy and Extracellular Vesicle Secretion | |
| 新型藻蓝蛋白体连接蛋白ApcI调控Synechocystis sp. PCC 6803的高光适应 | Espinoza-Corral, R. | N/A | The new phycobilisome linker protein ApcI regulates high light adaptation in Synechocystis sp. PCC 6803 | |
| 一种针对本科研究生的ChatGPT辅助阅读协议，用于参与生物物理学文献 | Sambar, M. | N/A | A ChatGPT Assisted Reading Protocol for Undergraduate Research Students Engaging with Biophysics Literature | |
| 识别生长分化因子-15作为代谢功能障碍相关脂肪性肝炎的早期预测生物标志物：一项基于英国生物银行蛋白质组数据的嵌套病例对照研究 | Wang, H. | N/A | Identification of Growth Differentiation Factor-15 as An Early Predictive Biomarker for Metabolic Dysfunction-Associated Steatohepatitis: A Nested Case-control Study of UK Biobank Proteomic Data | |
| 评估从黄芩提取物中分离出的反式肉桂酸在体内实验中的降血糖活性 | Fedorova, A. M. | N/A | Assessment of the hypoglycemic activity of trans-cinnamic acid isolated from the extract of hairy rots Scutellaria baicalensis in in vivo experiments | |
| 对黑尿酸症的解剖学研究：对软骨和骨中褐黄病的全新见解 | Hughes, J. H. | N/A | An anatomical investigation of alkaptonuria: Novel insights into ochronosis of cartilage and bone | |
| 共转录RNA加工促进合子基因激活 | Xu, J. | N/A | Co-transcriptional RNA processing boosts zygotic gene activation | |
| 免疫样糖链感知与横向获取的糖链加工在微生物共生中协同调控宿主控制 | Jenkins, B. H. | N/A | Immune-like glycan-sensing and horizontally-acquired glycan-processing orchestrate host control in a microbial endosymbiosis | |
| 在Heliconius蝴蝶中特定模态的记忆增强 | Hodge, E. | N/A | Modality specific memory enhancement in Heliconius butterflies | |
| Megabouts：一种用于斑马鱼运动分析的灵活管道 | Jouary, A. | N/A | Megabouts: a flexible pipeline for zebrafish locomotion analysis | |
| 睡眠-觉醒状态在老鼠大脑的情感调节区域中被编码 | Walder-Christensen, K. | N/A | Sleep-wake states are encoded across emotion-regulation regions of the mouse brain | |
| 评估和比较非周期性神经活动的测量方法 | Donoghue, T. | N/A | Evaluating and Comparing Measures of Aperiodic Neural Activity | |
| 利用跨试验和行为会话的相关性来改进神经解码 | Zhang, Y. | N/A | Exploiting correlations across trials and behavioral sessions to improve neural decoding | |
| 灵长类灵巧手部运动的脊髓和皮质前运动控制 | Takei, T. | N/A | Spinal and cortical premotor control of primate dexterous hand movements | |
| 多路复用推断的尖峰计数分析（SCAMPI） | Chen, Y. | N/A | Spike Count Analysis for MultiPlexing Inference (SCAMPI) | |
| 果蝇味觉回路的连接组分析 | Walker, S. R. | N/A | Connectomic analysis of taste circuits in Drosophila | |
| 不同类型急性运动对皮质醇水平和认知功能影响的比较研究 | Shao, Z. | N/A | Comparative study on the effects of different types of acute exercise on cortisol levels and cognitive functions | |
| 联会复合体在减数分裂期间保护双Holliday连接体 | Tang, S. M. | N/A | Synaptonemal complex protects double-Holliday junctions during meiosis | |
| 应激颗粒的形成使癌细胞能够在无锚定条件下生存。 | Yang, S. | N/A | Stress granule formation enables anchorage-independence survival in cancer cells | |
| 从头设计用于GPCR研究的融合蛋白工具 | Gao, K. | N/A | De novo Design of A Fusion Protein Tool for GPCR Research | |
| 脂质囊泡中膜弯曲与拉伸的耦合 | Wennerström, H. | N/A | On the coupling between membrane bending and stretching in lipid vesicles | |
| 条件定位药理学以时空精度操控细胞周期 | Deng, C. | N/A | Conditional Localization Pharmacology Manipulates the Cell Cycle with Spatiotemporal Precision | |
| PIP5K-Ras双稳态启动质膜对称性破坏，以调控细胞极性和迁移 | Deng, Y. | N/A | PIP5K-Ras bistability initiates plasma membrane symmetry breaking to regulate cell polarity and migration | |
| TAT-1是一种磷脂酰丝氨酸翻转酶，影响蜕皮过程并调控秀丽隐杆线虫表皮中的膜转运。 | Milne, S. M. | N/A | TAT-1, a phosphatidylserine flippase, affects molting and regulates membrane trafficking in the epidermis of C. elegans | |
| 变异进化图：我们能否推断SARS-CoV-2变种的演变过程？ | Das, B. | N/A | Variant Evolution Graph: Can We Infer How SARS-CoV-2 Variants are Evolving? | |
| 小乙型肝炎表面抗原的结构揭示了二聚体形成的机制 | He, X. | N/A | Structure of small HBV surface antigen reveals mechanism of dimer formation | |
| 部分修复导致尿路梗阻逆转后，乳头结构和功能出现永久性缺陷。 | Vanichapol, T. | N/A | Partial repair causes permanent defects in papillary structure and function after reversal of urinary obstruction | |
| 通过在酿酒酵母中的异源表达解码蓝细菌MysDs在类海藻氨基酸生物合成中的特异性 | Zheng, X. | N/A | Decoding Specificity of Cyanobacterial MysDs in Mycosporine-Like Amino Acid Biosynthesis through Heterologous Expression in Saccharomyces cerevisiae | |
| 光触发的蛋白酶介导的合成细胞中肌动蛋白结合货物的释放 | Akter, M. | N/A | Light-triggered protease-mediated release of actin-bound cargo from synthetic cells | |
| 肠道蠕虫通过使DC2向调节性表型发展，以对抗抗蠕虫免疫反应。 | Andrusaite, A. T. | N/A | Intestinal helminth skews DC2 development towards regulatory phenotype to counter the anti-helminth immune response. | |
| 莱姆病病原体中RpoS与BosR之间的正反馈调节 | Raghunandanan, S. | N/A | Positive feedback regulation between RpoS and BosR in the Lyme disease pathogen | |
| HIV-1融合肽在CD4诱导的包膜开放过程中的构象轨迹 | Thakur, B. | N/A | Conformational trajectory of the HIV-1 fusion peptide during CD4-induced envelope opening | |
| 两种与侵食松树的树皮甲虫相关的新物种Graphium（Microascales，子囊菌门）在中国被发现 | Li, J. | N/A | Two new species of Graphium (Microascales, Ascomycota) associated with pine-infesting bark beetles in China | |
| 双歧杆菌青春双歧杆菌CCDM 368的多糖BAP1通过抑制小鼠Th2免疫减轻卵清蛋白诱导的过敏反应 | Pacyga-Prus, K. | N/A | Polysaccharide BAP1 of Bifidobacterium adolescentis CCDM 368 attenuates ovalbumin-induced allergy through inhibition of Th2 immunity in mice | |
| 体外和体内HIV-1潜伏逆转通过Mukungulu，一种激活蛋白激酶C的非洲药用植物提取物 | Richard, K. | N/A | Ex vivo and in vivo HIV-1 latency reversal by Mukungulu, a protein kinase C-activating African medicinal plant extract | |
| 基因密码扩展揭示了活细胞中位点特异性的乳酸化，重塑了蛋白质功能 | Shao, C. | N/A | Genetic code expansion reveals site-specific lactylation in living cells reshapes protein function | |
| 细菌生长温度作为一种水平获得的聚基因性状 | Farrell, A. A. | N/A | Bacterial growth temperature as a horizontally acquired polygenic trait | |
| Tenascin C 缺失损害了肩袖修复后的肌腱愈合和功能恢复 | TASHJIAN, R. | N/A | Tenascin C Deletion Impairs Tendon Healing and Functional Recovery After Rotator Cuff Repair | |
| 全面的蛋白质基因组学和空间分析：转移性黑色素瘤对免疫检查点阻断疗法的先天性和获得性抗性的研究 | wei, s. | N/A | A Comprehensive Proteogenomic and Spatial Analysis of Innate and Acquired Resistance of Metastatic Melanoma to Immune Checkpoint Blockade Therapies | |
| H2B单泛素化在同源重组修复过程中D-loop代谢中的多方面作用 | Hung, S.-H. | N/A | Multifaceted roles of H2B mono-ubiquitylation in D-loop metabolism during homologous recombination repair | |
| Ripply3 过量使用通过在唐氏综合症模型中下调Tbx1，导致中面部缩短。 | Ahumada Saavedra, J. T. | N/A | Ripply3 overdosage induces mid-face shortening through Tbx1 downregulation in Down syndrome models. | |
| 同源多倍体杂交揭示八倍体草莓的起源 | Fan, Z. | N/A | Homoploid Hybridization Resolves the Origin of Octoploid Strawberries | |
| 发现并功能分析导致ROSAH综合征的新型ALPK1变异体 | Snelling, T. | N/A | Discovery and functional analysis of a novel ALPK1 variant causing ROSAH syndrome | |
| NuRD染色质重塑对于修复秀丽隐杆线虫生殖系中的外源性DSB是必需的。 | Ananthaswamy, D. | N/A | NuRD chromatin remodeling is required to repair exogenous DSBs in the Caenorhabditis elegans germline | |
| 酵母中携带缺失的线粒体DNA的遗传偏倚：拷贝数与细胞内选择的作用 | Kashko, N. D. | N/A | Inheritance bias of deletion-harbouring mtDNA in yeast: the role of copy number and intracellular selection | |
| 设计基于细胞的正交泛素转移级联系统以分析RBR E3 Parkin的底物 | Fang, S. | N/A | Engineering a Cell-Based Orthogonal Ubiquitin Transfer Cascade for Profiling the Substrates of RBR E3 Parkin | |
| 通过3D生物打印组织特异性高细胞密度生物墨水进行工程化组织的生物制造 | Jeon, O. | N/A | Biofabrication of engineered tissues by 3D bioprinting of tissue specific high cell-density bioinks | |
| 利用无细胞人羊膜进行小血管移植物的生物制造：一项在猪模型中的概念验证研究 | Aung, O. | N/A | Biofabrication of Small Vascular Graft with Acellular Human Amniotic Membrane: A Proof-of-Concept Study in Pig | |
| 更新的AL-Base显示，在AL淀粉样变性中，免疫球蛋白轻链可变基因存在等级富集。 | Morgan, G. J. | N/A | An updated AL-Base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis | |
| U2AF1 S34F通过与KRAS突变协同作用并改变对环境压力的反应，增强了肺细胞的肿瘤发生潜能。 | Liang, C. E. | N/A | U2AF1 S34F enhances tumorigenic potential of lung cells by exhibiting synergy with KRAS mutation and altering response to environmental stress | |
| 揭示CRBN分子胶水在化学蛋白质组学中的隐藏相互作用网络 | Baek, K. | N/A | Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics | |
| 番茄半胱氨酸蛋白酶抑制剂SlCYS8作为马铃薯干旱耐受性和块茎产量的触发因子 | Dorval, M. | N/A | Tomato cystatin SlCYS8 as a trigger of drought tolerance and tuber yield in potato | |
| 在没有联网污水处理设施的地区，对土壤传播的蠕虫和其他肠道病原体进行环境监测。 | Siko, J. E. E. | N/A | Environmental surveillance of soil-transmitted helminths and other enteric pathogens in settings without networked wastewater infrastructure | |
| SMARCAD1调控与癌症突变热点相关的活性复制叉处的R-环 | Uruci, S. | N/A | SMARCAD1 Regulates R-Loops at Active Replication Forks Linked to Cancer Mutation Hotspots | |
| # BioRxiv 2024-09-14 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 复杂非整倍体触发自噬和p53介导的凋亡，并损害人类植入前胚胎中的第二次谱系分离 | Regin, M. | N/A | Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos | |
| GEARBOCS：一种用于星形胶质细胞体内基因编辑的腺相关病毒工具 | Sivadasan Bindu, D. | N/A | GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes | |
| 肉食性有袋动物颅面发育过程中的基因调控动态 | Cook, L. E. | N/A | Gene regulatory dynamics during craniofacial development in a carnivorous marsupial | |
| 从自运动信号中抄近路：量化开放迷宫中的轨迹和主动感知 | Xu, J. | N/A | Shortcutting from self-motion signals: quantifying trajectories and active sensing in an open maze | |
| 稳态突触归一化优化了神经群体编码网络模型中的学习 | Mayzel, J. | N/A | Homeostatic synaptic normalization optimizes learning in network models of neural population codes | |
| 睾酮通过膜蛋白GPRC6A在斑马鱼胚胎中引起心脏水肿 | Zadmajid, V. | N/A | Testosterone acts through membrane protein GPRC6A to cause cardiac edema in zebrafish embryos | |
| G蛋白偶联受体TBXA2R激活ERM蛋白以调控三阴性乳腺癌细胞的迁移和侵袭。 | Leguay, K. | N/A | The G protein-coupled receptor TBXA2R activates ERMs to control cell motility and invasion of triple-negative breast cancer cells. | |
| CAMP：一个模块化的宏基因组分析系统，用于综合的多步骤数据探索 | Mak, L. | N/A | CAMP: A modular metagenomics analysis system for integrated multi-step data exploration | |
| 前额叶皮层第五层锥体神经元的特定亚型中存在特定异构体的烟碱样反应 | Patel, A. V. | N/A | Isoform-specific nicotinic responses are present in distinct subtypes of prefrontal layer V pyramidal neurons | |
| 一种毫秒级粗粒度模拟方法用于解析大麻素在甘氨酸受体α1上的别构结合 | Bartocci, A. | N/A | A millisecond coarse-grained simulation approach to decipher allosteric cannabinoid binding at the glycine receptor α1 | |
| 大型生物银行队列中随访数据的分析：方法学综述 | Kolde, A. | N/A | Analysis of follow-up data in large biobank cohorts: a review of methodology | |
| DNA修复背景与目标序列的相互作用可预测地偏向于Cas9生成的突变。 | Pallaseni, A. | N/A | The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations | |
| 溶酶体的外周定位支持黑色素瘤的侵袭性 | Jerabkova-Roda, K. | N/A | Peripheral positioning of lysosomes supports melanoma aggressiveness | |
| Fragle：利用深度学习对片段组学特征进行泛癌种循环肿瘤DNA定量 | Jacobsen Skanderup, A. | N/A | Fragle: Universal ctDNA quantification using deep learning of fragmentomic profiles | |
| 下一代杀虫剂氟吡呋喃酮与真菌病原体的协同效应 | Schlaeppi, D. | N/A | Synergistic effects of the next generation insecticide flupyradifurone with a fungalpathogen | |
| VACmap：一种用于解析复杂基因组重排的精确长读对齐工具 | Ding, H. | N/A | VACmap: An Accurate Long-Read Aligner for Unraveling Complex Genomic Rearrangements | |
| 时间和奖励的竞争性整合解释了价值敏感的觅食决策以及前额叶皮层的渐进动力学 | Bukwich, M. | N/A | Competitive integration of time and reward explains value-sensitive foraging decisions and frontal cortex ramping dynamics | |
| 亲吻素纤维及其受体分布分析表明，其在中枢感觉处理和行为状态控制中可能发挥作用。 | Zhang, L. | N/A | Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control | |
| 揭示区间通讯信号轴：线粒体至内质网应激反应（MERSR）及其对蛋白质稳态的影响 | Li, J. J. | N/A | Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response (MERSR) and its Impact on Proteostasis | |
| 健康老龄化中流体智力功能补偿的神经证据 | Knights, E. | N/A | Neural Evidence of Functional Compensation for Fluid Intelligence in Healthy Ageing | |
| 早期植入前酒精暴露后小鼠胎盘中性别特异性DNA甲基化和基因表达变化 | Legault, L.-M. | N/A | Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure | |
| 在空间解析的组学数据中，表征细胞类型在不同尺度上的空间关系 | dos Santos Peixoto, R. | N/A | Characterizing cell-type spatial relationships across length scales in spatially resolved omics data | |
| 芳香烃受体限制背根神经节神经元在损伤后的轴突再生 | Halawani, D. | N/A | Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury | |
| 视前区控制遗传性癫痫小鼠模型中与睡眠相关的癫痫发作起始 | Potesta, C. V. | N/A | Preoptic area controls sleep-related seizure onset in a genetic epilepsy mouse model | |
| 泛素特异性蛋白酶USP8的时空招募指导了内体成熟过程 | Miao, Y. | N/A | Spatiotemporal recruitment of the ubiquitin-specific protease USP8 directs endosome maturation | |
| TimberTracer：一个综合框架，用于评估森林管理和采伐木材产品替代对碳固存的影响。 | Boukhris, I. | N/A | TimberTracer: A Comprehensive Framework for the Evaluation of Carbon Sequestration by Forest Management and Substitution of Harvested Wood Products. | |
| 微管干扰后iPSC衍生模型系统中神经突延伸和核运动的测量 | Sebastien, M. | N/A | Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation | |
| 尼帕病毒融合蛋白的纳米级结构揭示了新的膜融合机制。 | Wang, Q. | N/A | The nanoscale organization of the Nipah virus fusion protein informs new membrane fusion mechanisms. | |
| MolSnapper：基于结构的药物设计中的条件扩散 | Ziv, Y. | N/A | MolSnapper: Conditioning Diffusion for Structure Based Drug Design | |
| 栖息地破碎化介导了鸟类长期气候驱动的热嗜性机制 | Liu, J. | N/A | Habitat fragmentation mediates the mechanisms underlying long-term climate-driven thermophilization in birds | |
| 催化功能不同的IDH1突变体在肿瘤模型中调节表型严重性 | Adam, M. A. A. | N/A | Catalytically distinct IDH1 mutants tune phenotype severity in tumor models | |
| 沙眼衣原体的T3SS结构基因和效应基因在不同的表型细胞形态中表达。 | Grieshaber, N. | N/A | The T3SS structural and effector genes of Chlamydia trachomatis are expressed in distinct phenotypic cell forms. | |
| 长精子优先权与果蝇（Drosophila melanogaster）中其他隐秘的雌性选择 | Peckenpaugh, B. | N/A | Long-sperm precedence and other cryptic female choices in Drosophila melanogaster | |
| SLC35G1：一种高度氯离子敏感的转运蛋白，负责肠上皮细胞基底侧膜的柠檬酸盐吸收转运。 | Mimura, Y. | N/A | SLC35G1: A highly chloride-sensitive transporter responsible for the basolateral membrane transport in intestinal citrate absorption | |
| 有丝分裂期间PI(3,5)P2不对称性对于不对称液泡遗传至关重要 | Huda, M. | N/A | PI(3,5)P2 asymmetry during mitosis is essential for asymmetric vacuolar inheritance | |
| 青少年时期大脑形态与认知功能之间的关联：基于9至15岁全面大规模分析的见解 | Yan, J. | N/A | Association between Brain Morphometry and Cognitive Function during Adolescence: Insights from a Comprehensive Large-Scale Analysis from 9 to 15 Years Old | |
| MIROSLAV：一个完整的开源硬件和软件工具包，用于啮齿动物高吞吐量昼夜节律活动测量和分析 | Virag, D. | N/A | MIROSLAV: A complete open-source hardware and software toolkit for high-throughput circadian activity measurement and analysis in rodents | |
| B细胞受体依赖性增强登革病毒感染 | Gebo, C. | N/A | B cell receptor dependent enhancement of dengue virus infection | |
| TRPML1门控通过别构突变和脂质的调节 | Gan, N. | N/A | TRPML1 gating modulation by allosteric mutations and lipids | |
| 刺胞动物XIAP激活半胱天冬酶介导的细胞死亡 | Chen, Y. | N/A | Cnidaria XIAP activates caspase-mediated cell death | |
| 直接从梨状皮层到听觉皮层的投射塑造了听觉与嗅觉的整合 | Vogler, N. W. | N/A | Direct piriform-to-auditory cortical projections shape auditory-olfactory integration | |
| 理解压力变性的物理决定因素：利用高压核磁共振技术探究Yfh1在不同温度下的展开途径 | Roumestand, C. | N/A | Understanding the physical determinants of pressure denaturation: Exploring the unfolding pathways of Yfh1 at different temperatures with High-Pressure NMR | |
| CRISPR RNA结合驱动结构有序化，为Cas7-11的靶标切割做好准备 | Lin, C. P. | N/A | CRISPR RNA binding drives structural ordering that primes Cas7-11 for target cleavage | |
| 不同表型水稻干旱和盐胁迫公共RNA测序数据的Meta分析 | Shintani, M. | N/A | Meta-analysis of public RNA-sequencing data of drought and salt stresses in different phenotypes of Oryza sativa | |
| 肾癌细胞通过吞噬作用和水平基因转移获取免疫表面蛋白 | Marcarian, H. Q. | N/A | Renal cancer cells acquire immune surface protein through trogocytosis and horizontal gene transfer | |
| 无序蛋白质及其凝聚物的酶促磷酸化分子模拟 | Zippo, E. | N/A | Molecular simulations of enzymatic phosphorylation of disordered proteins and their condensates | |
| 单胺氧化酶C（MAO C）的进化与功能分析：MAO基因家族的新成员 | Merello, G. | N/A | Evolutionary and Functional Analysis of Monoamine Oxidase C (MAO C): A Novel Member of the MAO Gene Family | |
| 原子级自由能景观揭示了蜜二糖转运蛋白的协同共转运机制 | Liang, R. | N/A | Atomic-Level Free Energy Landscape Reveals Cooperative Symport Mechanism of Melibiose Transporter | |
| 电鳗（Electrophorus）电器官中由腹侧向背侧的电细胞发育。 | Senarat, S. | N/A | Ventral-to-dorsal electrocyte development in electric organs of electric eel (Electrophorus). | |
| 评估用于跨癌症适应症比较蛋白质表达的计算方法 | Wang, J. | N/A | Evaluating computational approaches for comparison of protein expression across cancer indications | |
| AlphaFold2 SLiM筛选自噬中LC3-LIR相互作用 | Stuke, J. F. M. | N/A | AlphaFold2 SLiM screen for LC3-LIR interactions in autophagy | |
| 小鼠心脏中伴侣蛋白复合物的年龄相关变化 | Bhat, P. D. | N/A | Age-dependent Changes in a Chaperone Complex in the Mouse Heart | |
| 白色念珠菌与粪肠球菌之间的跨菌种宿主细胞协同损伤 | Kapitan, M. | N/A | Synergistic cross-kingdom host cell damage between Candida albicans and Enterococcus faecalis | |
| CNValidatron，利用计算机视觉实现CNV调用的自动化验证 | Montalbano, S. | N/A | CNValidatron, automated validation of CNV calls using computer vision | |
| 使用结构方程模型预测噪声中语音识别能力：基于静态与动态听觉图形-背景分析 | Guo, X. | N/A | Predicting speech-in-noise ability with static and dynamic auditory figure-ground analysis using structural equation modelling | |
| 在海马体的循环网络模型中，条形码活动能够实现高效的记忆绑定。 | Fang, C. | N/A | Barcode activity in a recurrent network model of the hippocampus enables efficient memory binding | |
| 番茄和茄子幼苗茎部软化和半透明形态学特征，由Ralstonia pseudosolanacearum F1C1感染引起 | Bhuyan, S. | N/A | Morphology of softening and translucency in the stems of tomato and eggplant seedlings due to infection by Ralstonia pseudosolanacearum F1C1 | |
| Colora：一个用于完成染色体规模从头基因组组装的Snakemake工作流程 | Obinu, L. | N/A | Colora: A Snakemake Workflow for Complete Chromosome-scale De Novo Genome Assembly | |
| 骨附着土壤作为目标和环境DNA及蛋白质的来源 | de Dios Martinez, T. | N/A | Bone adhered soil as a source of target and environmental DNA and proteins | |
| 解剖变异及其他血管因素对筛板低氧的影响 | Lu, Y. | N/A | Impact of anatomic variability and other vascular factors on lamina cribrosa hypoxia | |
| 使用单细胞RNA测序数据的拷贝数变异推断方法基准研究 | Chen, X. | N/A | A benchmarking study of copy number variation inference methods using single-cell RNA-sequencing data | |
| spaDesign：一种改进基于测序的空间转录组学实验设计的统计框架 | Xie, J. | N/A | spaDesign: A Statistical Framework to Improve the Design of Sequencing-based Spatial Transcriptomics Experiments | |
| Convpaint - 使用预训练神经网络进行交互式像素分类的通用框架 | Hinderling, L. | N/A | Convpaint - Universal framework for interactive pixel classification using pretrained neural networks | |
| 增强NADPH以恢复G6PD缺乏的微胶质细胞中的氧化还原稳态和溶酶体功能 | Mondal, A. | N/A | Enhancing NADPH to Restore Redox Homeostasis and Lysosomal Function in G6PD-Deficient Microglia | |
| 环境介导的相互作用导致微生物中外部化和集体记忆的形成 | Gajrani, S. | N/A | Environment-mediated interactions cause an externalized and collective memory in microbes | |
| 拟病毒、类Sputnik病毒和转拟病毒之间的寄生和共生相互作用：理论和动力系统方法。 | ORTEGA ATEHORTUA, E. | N/A | Parasitic and Commensal interactions among Mimiviruses, Sputnik-like virophages, and Transpovirons: A theoretical and dynamical systems approach. | |
| 肌因子FGF21与ALS中增强的生存率相关，并能减轻应激诱导的细胞毒性。 | Guha, A. | N/A | The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity | |
| 人类视觉皮层在准备期间的双格式注意力模板 | Chen, Y. | N/A | Dual-format attentional template during preparation in human visual cortex | |
| 人类气味辨别学习中特异性和迁移的对比模式 | Chang, X. | N/A | Contrasting patterns of specificity and transfer in human odor discrimination learning | |
| 酒精和可卡因滥用对成人海马体神经元和非神经元细胞周转的影响 | Alkass, K. | N/A | Effect of Alcohol and Cocaine Abuse on Neuronal and Non-Neuronal Cell Turnover in the Adult Human Hippocampus | |
| 缺乏皮质抑素会加重中风后的神经功能损伤，并加剧与衰老相关的神经胶质和血管功能障碍。 | Castillo Gonzalez, J. | N/A | Lack of cortistatin worsens neurological outcome and exacerbates aging-related glial and vascular dysfunction in stroke | |
| 枝角类物种的共存如何影响它们的肠道微生物群？ | Houwenhuyse, S. | N/A | How does co-occurrence of Daphnia species affect their gut microbiome? | |
| 在长期石灰性草地实验中，绵羊放牧并未增强土壤碳的持久性。 | Encarnation, D. | N/A | No enhancement of soil carbon persistence by sheep grazing in a long-term calcareous grassland experiment | |
| 扩展表型影响社会性蜘蛛的集体行为和生存 | Parthasarathy, B. | N/A | Extended Phenotype Influences Collective Behaviour and Survival in a Social Spider | |
| 比较转录组和变异分析揭示了肥胖型2型糖尿病大鼠模型胰腺胰岛中脂质运载蛋白2基因的常见分布无义突变 | Yokoi, N. | N/A | Comparative transcriptome and variant analyses of the pancreatic islets of a rat model of obese type 2 diabetes identifies a frequently distributed nonsense mutation in the lipocalin 2 gene | |
| 茄科植物的全基因组和全遗传学揭示了同源基因在作物工程中的偶然性 | Benoit, M. | N/A | Solanum pan-genomics and pan-genetics reveal paralogs as contingencies in crop engineering | |
| 提出一种以轴突为中心的分析方法，用于研究眼内压引起的机械损伤 | Bansal, M. | N/A | Proposing a methodology for axon-centric analysis of IOP-induced mechanical insult | |
| 注意力机制和状态空间基因组语言模型中标记化影响的比较 | Lindsey, L. M. | N/A | A Comparison of Tokenization Impact in AttentionBased and State Space Genomic Language Models | |
| 揭示单细胞Hi-C数据中的多尺度建筑特征：使用scCAFE方法 | Wang, F. | N/A | Unveiling multi-scale architectural features in single-cell Hi-C data using scCAFE | |
| ProtRNA：一种通过跨模态迁移学习生成的蛋白质衍生RNA语言模型 | Zhang, R. | N/A | ProtRNA: A Protein-derived RNA Language Model by Cross-Modality Transfer Learning | |
| m6AConquer：一个用于m6A检测技术统一量化与整合的数据资源 | Zhao, X. | N/A | m6AConquer: a Data Resource for Unified Quantification and Integration of m6A Detection Techniques | |
| 新皮层和海马体的θ振荡追踪视听整合及言语记忆的重播 | Biau, E. | N/A | Neocortical and hippocampal theta oscillations track audiovisual integration and replay of speech memories | |
| 聚焦超声增强抗体递送用于帕金森病的治疗 | Kwon, N. | N/A | Focused ultrasound enhanced antibody delivery for the treatment of Parkinson's Disease | |
| 视黄酸介导的稳态可塑性驱动伏隔核核心细胞类型特异性CP-AMPAR积累及可卡因渴求的孵化 | Hwang, E.-K. | N/A | Retinoic acid-mediated homeostatic plasticity drives cell type-specific CP-AMPAR accumulation in nucleus accumbens core and incubation of cocaine craving | |
| 较低的感知压力水平在自然处理过程中增强了感知和注意皮层的神经同步性。 | Craig, J. | N/A | Lower perceived stress enhances neural synchrony in perceptual and attentional cortices during naturalistic processing | |
| 在声音新奇性的进化过程中，运动皮层投射的选择性扩展 | Isko, E. C. | N/A | Selective expansion of motor cortical projections in the evolution of vocal novelty | |
| 操作性酒精自我给药方式通过调节伏隔核中含GluA2的AMPAR表达和突触活性，从而增强药物的强化特性。 | Faccidomo, S. | N/A | Operant alcohol self-administration targets GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens in a manner that drives the reinforcing properties of the drug | |
| 认知功能的调节器：小脑通过整合作用修改人类皮层网络动力学 | Bansal, K. | N/A | A modulator of cognitive function: Cerebellum modifies human cortical network dynamics via integration | |
| 不同的基底神经节决策动力学在冲突和不确定性下 | Ging-Jehli, N. R. | N/A | Distinct basal ganglia decision dynamics under conflict and uncertainty | |
| 视觉运动学习中的节省与小脑-丘脑-皮质网络内的连接性变化相关，该网络编码运动误差。 | Struber, L. | N/A | Savings in visuomotor learning is associated with connectivity changes within a cerebello-thalamo-cortical network encoding movement errors | |
| 神经肌肉骨骼建模揭示了感觉运动皮层中适应性学习的肌肉水平神经动态 | DeWolf, T. | N/A | Neuro-musculoskeletal modeling reveals muscle-level neural dynamics of adaptive learning in sensorimotor cortex | |
| CHCHD2-CHCHD10蛋白复合物受线粒体功能障碍的调节，并改变小鼠大脑中的脂质稳态。 | Gerlach, J. | N/A | The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain. | |
| 纵向多组学免疫分析揭示了健康成年人中与年龄相关的免疫细胞动态变化 | Gong, Q. | N/A | Longitudinal Multi-omic Immune Profiling Reveals Age-Related Immune Cell Dynamics in Healthy Adults | |
| 利用位点频率比区分选择性与非选择性力量 | Hey, J. | N/A | Isolating selective from non-selective forces using site frequency ratios | |
| 基于基因的适应性模型及其对遗传变异的启示 | Johri, P. | N/A | A gene-based model of fitness and its implications for genetic variation | |
| 推动单分子转录组测序的极限，以揭示人类视网膜神经中最大的疾病相关转录本异构体 | Stemerdink, M. | N/A | Pushing the limits of single molecule transcript sequencing to uncover the largest disease-associated transcript isoforms in the human neural retina | |
| 行为证据表明存在两种注意模式 | Gupta, A. | N/A | Behavioral Evidence for Two Modes of Attention | |
| 篮状细胞中的双峰树突处理驱动与记忆相关的不同振荡 | Tzilivaki, A. | N/A | Bimodal dendritic processing in basket cells drives distinct memory-related oscillations | |
| 一种应激诱导的逆行线粒体运输的分子开关 | Gladkova, C. | N/A | A molecular switch for stress-induced activation of retrograde mitochondrial transport | |
| CD11B+CD36+细胞是促进骨形成的巨噬细胞，能够限制与年龄相关的骨质流失。 | Koroth, J. | N/A | CD11B+CD36+ cells are bone anabolic macrophages that limit age-associated bone loss | |
| CD34+基质细胞/端粒细胞在中年斯普拉格-道利大鼠心肌梗死后愈合过程中表现出动态分布模式 | Schneider, D. T. | N/A | CD34+ Stromal Cell/Telocytes Demonstrate a Dynamic Pattern of Distribution During Healing of Post-Infarcted Myocardium in Middle-Aged Sprague-Dawley Rats | |
| 分析细胞中异常折叠状态蛋白质纤维化的生理影响 | Levin, T. | N/A | Profiling the physiological impact of aberrant folded-state protein filamentation in cells | |
| 神经纤维瘤蛋白丢失通过GLUT1激活诱导炎症性巨噬细胞表型转换和视网膜新生血管形成 | ZAIDI, Y. | N/A | Loss of Neurofibromin Induces Inflammatory Macrophage Phenotypic Switch and Retinal Neovascularization via GLUT1 Activation | |
| 细胞应激对SERPINA1 3'UTR中改变的多聚腺苷酸化位点使用影响A1AT蛋白表达 | Jiamutai, F. | N/A | Altered polyadenylation site usage in SERPINA1 3'UTR in response to cellular stress affects A1AT protein expression | |
| 急性西地那非给药可降低绵羊对诱发性心房颤动的易感性 | denham, N. | N/A | Acute sildenafil administration reduces susceptibility to induced atrial fibrillation in sheep | |
| 多层记忆痕迹中的任务相关表征格式 | Heinen, R. | N/A | Task-relevant representational formats in multi-layered memory traces | |
| 行为谱显示，大鼠对一种恐惧条件下的视觉线索表现出多样行为的组织能力。 | Williams, D. C. | N/A | Ethograms reveal a fear conditioned visual cue to organize diverse behaviors in rats | |
| 人微小RNA-153-3p靶向特定的神经元基因，并与阿尔茨海默病的风险相关。 | Wang, R. | N/A | Human microRNA-153-3p targets specific neuronal genes and is associated with the risk of Alzheimer's disease. | |
| 精神分裂症患者免疫细胞中IKZF1-IKZF2串联的双重打击调节特定症状 | Ballasch, I. | N/A | A double hit affecting the IKZF1-IKZF2 tandem in immune cells of schizophrenic patients regulate specific symptoms | |
| 表观遗传适应驱动单核细胞在移植入视网膜后分化为类似小胶质细胞的细胞 | Liu, J. | N/A | Epigenetic adaptation drives monocyte differentiation into microglia-like cells upon engraftment into the retina | |
| 用于可预测、精确的双水平调控哺乳动物重组蛋白表达的合成G四链体元件 | Pohle, M. | N/A | Synthetic G-quadruplex components for predictable, precise two-level control of mammalian recombinant protein expression | |
| 肽激动剂解离和粘附G蛋白偶联受体失活的机制 | Joshi, K. | N/A | Mechanisms of peptide agonist dissociation and deactivation of adhesion G-protein-coupled receptors | |
| 初级纤毛促进EMT诱导的三阴性乳腺癌肿瘤异质性和对治疗的抵抗性 | Tessier, C. | N/A | Primary cilia promote EMT-induced triple-negative breast tumor heterogeneity and resistance to therapy | |
| NEK9敲除通过诱导ERK介导的癌细胞焦亡重塑多西他赛耐药性 | Ansari, S. A. | N/A | NEK9 ablation rewires docetaxel resistance through induction of ERK-mediated cancer cell pyroptosis | |
| RAD50是一种潜在的乳腺癌诊断和预后生物标志物。 | Chhatwal, K. S. | N/A | RAD50 is a potential biomarker for breast cancer diagnosis and prognosis | |
| 通过理性受体工程解锁扩展的鞭毛蛋白感知 | Li, T. | N/A | Unlocking expanded flagellin perception through rational receptor engineering | |
| 高脂饮食对小鼠下丘脑反应的性别依赖性影响 | Dreux, V. | N/A | Sex-dependent effects of a high-fat diet on the hypothalamic response in mouse | |
| TAAR1部分激动剂诱导的觉醒通过多巴胺能神经传递介导 | Park, S. | N/A | Wakefulness induced by TAAR1 partial agonism is mediated through dopaminergic neurotransmission | |
| 通过电子断层扫描技术对脑内皮细胞的超微结构进行分析 | Kotchetkov, P. | N/A | Ultrastructural analysis of the brain endothelium by electron tomography | |
| 在正常生理条件下，基于统计稳健性的轴突髓鞘单元模型及其在疾病状态中的应用 | Gow, A. | N/A | A Statistically-Robust Model Of The Axomyelin Unit Under Normal Physiologic Conditions With Application To Disease States | |
| 分带运动适应相关的皮层-肌肉耦合的调制 | Oshima, A. | N/A | Modulation of cortico-muscular coupling associated with split-belt locomotor adaptation | |
| 刺伤伤口引发实质性星形胶质细胞中的过渡放大祖细胞样表型 | Ninkovic, J. | N/A | Stab Wound Injury Elicits Transit Amplifying Progenitor-like Phenotype in Parenchymal Astrocytes | |
| 通过蛋白质语言模型从氨基酸序列预测蛋白质半衰期 | Sagawa, T. | N/A | Prediction of Protein Half-lives from Amino Acid Sequences by Protein Language Models | |
| 一个用于SubtiWiki的新框架，SubtiWiki是模式生物枯草芽孢杆菌的数据库 | Elfmann, C. | N/A | A new framework for SubtiWiki, the database for the model organism Bacillus subtilis | |
| 识别、优先排序和可视化功能性启动子单核苷酸变异（SNVs）：使用复发无关的REMIND-Cancer管道和pSNV Hunter | Abad, N. A. B. | N/A | Identifying, Prioritizing, and Visualizing Functional Promoter SNVs with the Recurrence-agnostic REMIND-Cancer Pipeline and pSNV Hunter | |
| 针对施万细胞EP2/cAMP纳米域以阻断疼痛但不阻断炎症 | Nassini, R. | N/A | Targeting the Schwann Cell EP2/cAMP Nanodomain to Block Pain but not Inflammation | |
| 靶向细胞器中蛋白酶激活受体2信号的纳米药物提供持续镇痛效果 | Teng, S. L. | N/A | Nanomedicines targeting signaling of protease-activated receptor 2 in organelles provide sustained analgesia | |
| 单细胞实验的顺序设计以识别基因表达的离散随机模型。 | Cook, J. | N/A | Sequential design of single-cell experiments to identify discrete stochastic models for gene expression. | |
| 揭示种族间面孔感知背后的神经表征 | Shoura, M. | N/A | Revealing the neural representations underlying other-race face perception | |
| 乳腺癌中驱动下丘脑-垂体-肾上腺轴功能障碍的脑-体反馈回路 | Gomez, A. | N/A | A brain-body feedback loop driving HPA-axis dysfunction in breast cancer | |
| TAAR2-9敲除小鼠表现出觉醒度降低和快速眼动睡眠（REM睡眠）紊乱 | Park, S. | N/A | TAAR2-9 Knockout Mice Exhibit Reduced Wakefulness and Disrupted REM Sleep | |
| 心脏、呼吸和胃的节律独立地调节皮层脊髓兴奋性。 | Engelen, T. | N/A | The cardiac, respiratory and gastric rhythms independently modulate corticospinal excitability | |
| Parechovirus-3感染破坏了免疫代谢，并导致神经类器官中的谷氨酸兴奋性毒性 | Capendale, P. E. | N/A | Parechovirus-3 infection disrupts immunometabolism and leads to glutamate excitotoxicity in neural organoids | |
| 过敏原免疫后，2型常规树突状细胞中的IFN-I信号支持TH2和T滤泡辅助细胞的分化。 | Webb, G. R. | N/A | IFN-I signaling in type 2 conventional dendritic cells supports TH2 and T follicular helper differentiation after allergen immunization | |
| 用于性别鉴定的高保真遗传标记，适用于大麻（Cannabis sativa）幼苗的性别鉴定。 | Prentout, D. | N/A | High fidelity genetic markers for sexing Cannabis sativa seedlings | |
| 布朗运动数据增强：一种提升神经网络在纳米孔传感器性能的方法 | Kipen, J. | N/A | Brownian motion data augmentation: a method to push neural network performance on nanopore sensors | |
| 糖尿病视网膜病变中自噬相关基因的鉴定与验证 | Peng, W. | N/A | Identification and Validation of Mitophagy-Related Genes in Diabetic Retinopathy | |
| 量子力学预测Bicoid的解读时间不到一秒。 | Lone, I. | N/A | Quantum mechanics predicts Bicoid interpretation times of less than a second | |
| 血小板PI3Kβ调控乳腺癌转移 | Graff, R. C. | N/A | Platelet PI3Kβ regulates breast cancer metastasis | |
| RAD23A的减少可延长寿命并减轻TDP-43小鼠的病理症状 | Xueshui, G. n. | N/A | Reduction of RAD23A extends lifespan and mitigates pathology in TDP-43 mice | |
| 去蜡人脑组织的定量细胞结构表型分析 | Di Meo, D. | N/A | Quantitative cytoarchitectural phenotyping of deparaffinized human brain tissues | |
| 胆碱能反馈用于特定情境下对感觉表征的调节 | Yu, B. | N/A | Cholinergic feedback for context-specific modulation of sensory representations | |
| 在观察者的大脑中：双稳态运动揭示了V1区域中尺度反馈调制的存在 | Pizzuti, A. | N/A | In the brain of the beholder: bi-stable motion reveals mesoscopic-scale feedback modulation in V1 | |
| 早期至中期儿童非周期性脑电活动的纵向轨迹 | Sacks, D. D. | N/A | Longitudinal trajectories of aperiodic EEG activity in early to middle childhood | |
| G-CSF和IL-6在严重病毒感染期间驱动髓系失调 | Kajihara, K. | N/A | G-CSF and IL-6 drive myeloid dysregulation during severe viral infection | |
| BRUCE肝虚证通过损害肝细胞的线粒体代谢和激活肝星状细胞中的STAT3信号，在PTEN肝虚证的背景下加剧了MASLD/MASH。 | Che, L. | N/A | BRUCE liver-deficiency potentiates MASLD/MASH in PTEN liver-deficient background by impairment of mitochondrial metabolism in hepatocytes and activation of STAT3 signaling in hepatic stellate cells | |
| 中东呼吸综合征冠状病毒的持续演变，沙特阿拉伯王国，2023-2024年 | Hassan, A. M. | N/A | Ongoing evolution of Middle East Respiratory Syndrome Coronavirus, Kingdom of Saudi Arabia, 2023-2024 | |
| SCAMPI：一种可扩展的统计框架，用于利用跨性状相关性进行全基因组交互测试 | Bian, S. | N/A | SCAMPI: A scalable statistical framework for genome-wide interaction testing harnessing cross-trait correlations | |
| 亚细胞水平空间转录组学与PHOTON | Rajachandran, S. | N/A | Subcellular Level Spatial Transcriptomics with PHOTON | |
| 通过结合高通量筛选实验与非靶向代谢组学方法，探究美洲接骨木化合物在抗氧化、抗病毒和抗菌特性方面的潜力。 | Dwikarina, A. | N/A | Exploring American Elderberry Compounds for Antioxidant, Antiviral, and Antibacterial Properties Through High-Throughput Screening Assays Combined with Untargeted Metabolomics | |
| 快速生产来自类精干细胞的改良牛羊 | Yang, L. | N/A | Rapid production of modified cattle and sheep from spermatid-like stem cells | |
| 随机取向的微槽水凝胶引导细胞运动，调节运动速度，并控制细胞扩散的方向性。 | Ghosh, B. | N/A | Randomly oriented microgrooved hydrogel guides cellular motility, modulates speed, and governs directionality of cellular spread | |
| 手性组氨酸富集肽凝聚体增强抗原向T细胞的递送 | Pramanik, U. | N/A | Enantiomeric histidine-rich peptide coacervates enhance antigen delivery to T cells | |
| 动态关联（Associations on the Fly）是一项新功能，旨在促进对Open Targets平台证据的探索。 | Cruz-Castillo, C. | N/A | Associations on the Fly, a new feature aiming to facilitate exploration of the Open Targets Platform evidence | |
| 通过局部几何生成进行三维分子预训练 | Sun, Y. | N/A | 3D Molecular Pretraining via Localized Geometric Generation | |
| 不同的基质细胞群定义了B细胞急性淋巴母细胞白血病的微环境 | Blanco, M. N. F. | N/A | Distinct Stromal Cell Populations Define the B-cell Acute Lymphoblastic Leukemia Microenvironment | |
| 优化形状定义微粒的制备以实现持续药物递送：“少即是多”范式 | Murgia, D. | N/A | Optimizing The Fabrication Of Shape-Defined Microparticles For Sustained Drug Delivery: The 'Less Is More' Paradigm | |
| 缺血再灌注后外肾髓优先损伤依赖于高氧化代谢 | Arnoux, G. | N/A | The preferential injury of outer renal medulla after ischemia-reperfusion relies on high oxidative metabolism | |
| 高剂量大麻二酚预处理对抗阿片类药物引起的持续性呼吸暂停的概念验证 | Wiese, B. M. | N/A | Proof of Concept for High-Dose Cannabidiol Pretreatment to Antagonize Opioid Induced Persistent Apnea | |
| 全身麻醉激活的中央杏仁核神经元在神经病理性疼痛的急性期和晚期阶段的不同作用 | Zhao, J. | N/A | Distinct roles of general anesthesia activated CeA neurons in acute versus late phase of neuropathic pain | |
| 物体非刚性的各向异性：皮层各向异性的高级知觉后果 | Maruya, A. | N/A | Anisotropy of object non-rigidity: High-level perceptual consequences of cortical anisotropy | |
| 致病性微生物群通过改变能量代谢破坏脑类器官的完整结构 | Isik, M. | N/A | Pathogenic microbiota disrupts the intact structure of cerebral organoids by altering energy metabolism | |
| 糖脂质系统对α-突触核蛋白传播的影响：水通道蛋白-4和肌营养不良蛋白相关蛋白复合物的作用 | Lopes, D. M. | N/A | Influence of the Glymphatic System on α-Synuclein Propagation: Role of Aquaporin-4 and the Dystrophin-Associated Protein Complex | |
| 使用即兴演讲（IMPRO）的新压力诱发协议的有效性 | Saskovets, M. | N/A | Validity of a New Stress Induction Protocol using Speech Improvisation (IMPRO) | |
| 通过脑机接口对皮层波进行操作性条件反射 | Dogadov, A. | N/A | Operant conditioning of cortical waves through a brain-machine interface | |
| PLCγ2的保护性变体通过增强有益的微胶质细胞功能，减轻了与阿尔茨海默病相关的病理。 | Takalo, M. | N/A | Protective variant in PLCgamma2 mitigates Alzheimer's disease associated pathology via enhancing beneficial microglia functions | |
| 成年少突胶质细胞生成通过ADAMTS4重塑血脑屏障来调控弓状核神经元的葡萄糖感应 | Buller, S. | N/A | Adult oligodendrogenesis gates arcuate neuronal glucose sensing through remodelling of the blood-hypothalamus barrier via ADAMTS4 | |
| 胰岛淀粉样蛋白破坏MHC II类抗原呈递，并保护NOD小鼠免受自身免疫性糖尿病的影响。 | Denroche, H. C. | N/A | Islet amyloid disrupts MHC Class II antigen presentation and protects NOD mice from autoimmune diabetes. | |
| 单细胞和时空转录组分析揭示委内瑞拉马脑炎病毒感染后脑部免疫浸润情况 | Rangel, M. | N/A | Single-cell and spatiotemporal transcriptomic profiling of brain immune infiltration following Venezuelan equine encephalitis virus infection | |
| SARS-CoV-2蛋白ORF3a诱导溶酶体膜的Atg8化 | Ajnar, D. | N/A | SARS-CoV-2 protein ORF3a induces Atg8ylation of lysosomal membranes | |
| 利用相关性和机制性物种分布模型预测当前和未来环境及气候变化下的虫媒疾病风险：以英国西尼罗河病毒为例的研究。 | Withers, A. J. | N/A | Using correlative and mechanistic species distribution models to predict vector-borne disease risk for the current and future environmental and climatic change: a case study of West Nile Virus in the UK. | |
| 评估高致病性禽流感H5病毒在法国肉鸡和蛋鸡生产网络中传播的风险 | Hautefeuille, C. | N/A | Assessing the risk of highly pathogenic avian influenza H5 viruses spread within French broiler and layer production networks | |
| 苔藓藻基因组：绿色植物多细胞化和陆地化的替代机制 | Caisova, L. | N/A | The Draparnaldia genome: alternative mechanisms for multicellularity and terrestrialization in green plants | |
| EBAX-1/ZSWIM8 破坏 miRNA，导致捕食特征的跨代记忆 | Quiobe, S. P. | N/A | EBAX-1/ZSWIM8 destabilizes miRNAs resulting in transgenerational memory of a predatory trait | |
| 长链非编码RNA TAAL是糖尿病视网膜病变中Tie1介导的血管功能的调节因子 | Ranjan, G. | N/A | LncRNA TAAL is a Modulator of Tie1-Mediated Vascular Function in Diabetic Retinopathy | |
| 单倍型解析的基因组组装为新疆最古老的葡萄品种（木纳格）的基因组构成提供了深入见解。 | Zhong, H. | N/A | Haplotype-resolved assemblies provide insights into genomic makeup of the oldest grapevine cultivar (Munage) in Xingjiang | |
| DiatOmicBase是一个以基因为中心的平台，用于挖掘硅藻基因组间的功能组学数据。 | Villar, E. | N/A | DiatOmicBase, a gene-centered platform to mine functional omics data across diatom genomes | |
| 内皮糖萼的成熟度水平调节其与带电纳米材料的相互作用 | Bridges, C. | N/A | The level of endothelial glycocalyx maturity modulates interactions with charged nano-materials | |
| 蛋白质冠组成因果分析：磷脂酰胆碱通过蛋白质组学增强血浆蛋白质组谱分析 | Rafieioskouei, A. | N/A | Causality Analysis of Protein Corona Composition: Phosphatidylcholine-Enhances Plasma Proteome Profiling by Proteomics | |
| ScReNI：通过整合scRNA-seq和scATAC-seq数据进行单细胞调控网络推断 | Xu, X. | N/A | ScReNI: single-cell regulatory network inference through integrating scRNA-seq and scATAC-seq data | |
| LoVis4u：用于比较基因组的位点可视化工具 | Egorov, A. A. | N/A | LoVis4u: Locus Visualisation tool for comparative genomics | |
| SVbyEye：一种用于描述全基因组组装间结构变异的视觉工具 | Porubsky, D. | N/A | SVbyEye: A visual tool to characterize structural variation among whole genome assemblies | |
| 一种高通量表型筛选结合基于超大规模深度学习的虚拟筛选揭示了新型抗菌化合物骨架 | Scalia, G. | N/A | A high-throughput phenotypic screen combined with an ultra-large-scale deep learning-based virtual screening reveals novel scaffolds of antibacterial compounds | |
| 考古记录中β-乳球蛋白肽的存续性：脆弱性与序列变异 | Fonseca, B. | N/A | The Survival of β-lactoglobulin Peptides in the Archaeological Record: Vulnerability vs. Sequence Variation | |
| 光惰性气体对脂质过氧化引起的化学发光可能的作用机制 | Oliynyk, I. | N/A | Possible Mechanisms Of Action Of Light Inert Gases On Chemiluminescence Arising As A Result Of Lipid Peroxidation | |
| BST2在癌症进展过程中诱导血管平滑肌细胞的可塑性和表型转换 | Bell, C. | N/A | BST2 induces vascular smooth muscle cell plasticity and phenotype switching during cancer progression | |
| 癌症适应性治疗周期设计与稳定性：确定性与随机性模型 | Vilela, Y. G. | N/A | On the design and stability of cancer adaptive therapy cycles: deterministic and stochastic models | |
| 骨髓中的转移性肿瘤细胞与配对的神经母细胞瘤肿瘤不同，并包含具有治疗抵抗特性的亚群。 | Hochheuser, C. | N/A | Metastatic tumor cells in bone marrow differ from paired neuroblastoma tumor and contain subsets with therapy-resistant characteristics | |
| 使用深度学习从静息状态功能连接预测任务激活图 | Madsen, S. J. | N/A | Predicting Task Activation Maps from Resting-State Functional Connectivity using Deep Learning | |
| 增强初级视觉皮层与身体选择性皮层之间的前向连接，减少任务无关维度对身体判断的干扰 | Gandolfo, M. | N/A | Boosting forward connectivity between primary visual and body selective cortex reduces interference of task irrelevant dimensions on body judgements | |
| ARHGEF3调控毛囊形态发生 | Laurin, M. | N/A | ARHGEF3 Regulates Hair Follicle Morphogenesis | |
| 有益根际细菌和病毒感染调节大豆代谢组，并影响病毒媒介Epilachna varivestis的取食偏好。 | Pulido, H. | N/A | Beneficial rhizobacteria and virus infection modulate the soybean metabolome and influence the feeding preferences of the virus vector Epilachna varivestis. | |
| 足部放置控制在跨物种的稳定运动中起着基础作用 | De Comite, A. | N/A | Foot placement control underlies stable locomotion across species | |
| 评估携带SUB1和DRO1基因的IR64水稻近等基因系对逆境的耐受性 | Sakagami, J.-I. | N/A | Evaluation of stress tolerance in IR64 rice near-isogenic lines carrying SUB1 and DRO1 genes | |
| 对英国市场上销售的基于植物和肉类成分的完整干狗粮的营养分析 | Brociek, R. A. | N/A | Nutritional analysis of commercially available, complete plant- and meat-based dry dog foods in the UK | |
| 促炎介质使小鼠感觉神经元中的瞬时受体电位梅拉司林3型阳离子通道（TRPM3）信号传导敏感化 | Aguilera-Lizarraga, J. | N/A | Pro-inflammatory mediators sensitise Transient Receptor Potential Melastatin 3 cation channel (TRPM3) signalling in mouse sensory neurons | |
| 脊髓感觉运动回路在侧胸半横断后控制系带和分带步态相位持续时间的操作 | Rybak, I. A. | N/A | Operation of spinal sensorimotor circuits controlling phase durations during tied-belt and split-belt locomotion after a lateral thoracic hemisection | |
| 土壤氧化还原作用驱动病毒-宿主群落动态及热带雨林土壤中植物生物量的降解 | Trubl, G. | N/A | Soil redox drives virus-host community dynamics and plant biomass degradation in tropical rainforest soils | |
| 海洋酵母对基于昆布多糖的基质的利用和降解表明它们在微生物循环动力学中具有生态位特异性作用。 | Reich, M. | N/A | Utilization and degradation of laminarin-based substrates by marine yeasts suggests their niche-specific role in microbial loop dynamics. | |
| 表面介导的噬菌体防御对细菌间拮抗作用产生了适应性权衡 | Tsai, C.-E. | N/A | Surface-mediated Bacteriophage Defense Incurs Fitness Tradeoffs for Interbacterial Antagonism | |
| tRNA赖氨酰化对于恶性疟原虫顶质体中发现的最低翻译系统至关重要。 | Elahi, R. | N/A | tRNA lysidinylation is essential for the minimal translation system found in the apicoplast of Plasmodium falciparum | |
| 计算机分析显示，常用的PCR检测方法对肠道病毒物种的靶向性存在差异。 | Trinh, V. N. | N/A | In silico analysis reveals differential targeting of enterovirus species by commonly used PCR assays | |
| 应激诱导小蛋白的翻译谱分析揭示了不同信号系统之间意想不到的联系 | Vellappan, S. | N/A | Translational profiling of stress-induced small proteins uncovers an unexpected connection among distinct signaling systems | |
| 新加坡受试者粪便样本中分离的三种Acutalibacteraceae细菌的基因组重建与饮食反应评估。 | Park, M. A. | N/A | Genomic Reconstruction and Dietary Response Assessment of Three Acutalibacteraceae Bacteria Isolated from Fecal Samples of Singapore Subjects. | |
| 利用膜编辑结合邻近标记技术揭示的调控磷脂酸稳态的动态网络 | Tei, R. | N/A | Dynamic network regulating phosphatidic acid homeostasis revealed using membrane editing coupled to proximity labeling | |
| Nf1对睡眠行为的影响是通过SARM1依赖的NAD+代谢缺陷引起的饥饿所介导的。 | Sofela, F. A. | N/A | Effects of Nf1 on sleep behavior are mediated through starvation caused by deficits in SARM1 dependent NAD+ metabolism. | |
| 解释预测区间和分布以解码元分析中的生物普遍性 | Yang, Y. | N/A | Interpreting prediction intervals and distributions for decoding biological generality in meta-analyses | |
| 通过结肠发酵和小麦阿拉伯木聚糖的酶催化产生生物活性结构基序：体外、计算机模拟和功能分析提供的与Toll样受体相互作用的证据 | Guerreiro, C. d. A. | N/A | Production of bioactive structural motifs from wheat arabinoxylan via colonic fermentation and enzymatic catalysis: evidence of interaction with toll-like receptors from in vitro, in silico and functional analysis | |
| 鞘氨醇激酶1在脂肪来源干细胞中被糖皮质激素诱导，并增强糖皮质激素介导的脂肪扩张信号传导。 | Lambert, J. M. | N/A | Sphingosine kinase 1 is induced by glucocorticoids in adipose derived stem cells and enhances glucocorticoid mediated signaling in adipose expansion. | |
| 线粒体脂肪酸氧化受红光照射刺激 | Herrera, M. A. | N/A | Mitochondrial Fatty Acid Oxidation is Stimulated by Red Light Irradiation | |
| 异常剪接体中间体在其解体过程中的结构 | Soni, K. | N/A | Structures of aberrant spliceosome intermediates on their way to disassembly | |
| 机器学习增强的分子动力学模拟（MD）揭示了ZTPriboswitch配体的亲和力与激活之间的脱节现象。 | Fullenkamp, C. R. | N/A | Machine learning-augmented molecular dynamics simulations (MD) reveal insights into the disconnect between affinity and activation of ZTPriboswitch ligands | |
| 质子化/去质子化驱动的低电位铁氧还蛋白氧化还原稳定性的开关 | Wada, K. | N/A | Protonation/deprotonation-driven switch for the redox stability of low-potential ferredoxin | |
| 分子转子为α-突触核蛋白聚集物的形成和转化机制提供了深入见解。 | Allerton, S. C. | N/A | Molecular rotors provide insight into the mechanism of formation and conversion of α-synuclein aggregates | |
| 一种针对糖体膜生物合成的抑制剂可杀死利什曼原虫寄生虫。 | Chou, S.-E. | N/A | An inhibitor targeting glycosome membrane biogenesis kills Leishmania parasites | |
| AI生成的小型活页夹提升了主要编辑效果 | Park, J.-C. | N/A | AI-generated small binder improves prime editing | |
| 仿生病毒样颗粒调控细胞功能 | Maayouf, H. | N/A | Biomimetic Virus-Like Particles to control cell functions | |
| 计算机模拟研究：选择性生物碱作为阿尔茨海默病β和γ-分泌酶双重抑制剂 | Onifade, I. | N/A | In silico study of selected alkaloids as dual inhibitors of β and γ-Secretases for Alzheimer's disease | |
| 映射和建模内在神经时间尺度的年龄相关变化 | Wu, K. | N/A | Mapping and Modeling Age-Related Changes in Intrinsic Neural Timescales | |
| 利用预训练的深度蛋白质语言模型预测肽段的碰撞截面 | Nakai-Kasai, A. | N/A | Leveraging Pretrained Deep Protein Language Model to Predict Peptide Collision Cross Section | |
| 极端嗜热、分解木质纤维素的厌氧细菌Anaerocellum bescii（前称Caldicellulosiruptor bescii）中的麦芽糊精转运 | Tjo, H. | N/A | Maltodextrin Transport in the Extremely Thermophilic, Lignocellulose Degrading Bacterium Anaerocellum bescii (f. Caldicellulosiruptor bescii) | |
| 振动触觉耳迷走神经刺激在人类中改变边缘系统连接：一项初步研究 | Donovan, K. M. | N/A | Vibrotactile auricular vagus nerve stimulation alters limbic system connectivity in humans: A pilot study | |
| # BioRxiv 2024-09-13 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 大脑状态和皮层层特异性机制在感知阈值下的作用 | Morton, M. P. | N/A | Brain state and cortical layer-specific mechanisms underlying perception at threshold | |
| 跨多个脓肿分枝杆菌分离株的转座子测序揭示了菌株间显著的功能基因组多样性 | Akusobi, C. | N/A | Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains | |
| Kisspeptin纤维及其受体分布分析表明其在中枢感觉处理和行为状态控制中可能发挥的作用。 | Zhang, L. | N/A | Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control | |
| 核篮蛋白调控芽殖酵母中核孔复合体的分布和移动性 | Zsok, J. | N/A | Nuclear basket proteins regulate the distribution and mobility of nuclear pore complexes in budding yeast | |
| 呼吸与觉醒之间的动态联系 | Kluger, D. S. | N/A | A dynamic link between respiration and arousal | |
| Hill型方程揭示了由p53脉冲引导的目标蛋白质表达的调控原理。 | Shi, X. | N/A | The Hill-type equation reveals the regulatory principle of target protein expression led by p53 pulsing | |
| 伏隔核多巴胺释放反映了工具性学习过程中的贝叶斯推理 | Qu, A. J. | N/A | Nucleus accumbens dopamine release reflects Bayesian inference during instrumental learning | |
| 在转移性微环境中异常激活的伤口愈合程序促进了骨肉瘤细胞在肺部的定植。 | Reinecke, J. B. | N/A | Aberrant activation of wound healing programs within the metastatic niche facilitates lung colonization by osteosarcoma cells | |
| 高参数蛋白图谱揭示了早期发育中人类肺的空间组织结构 | Sariyar, S. | N/A | High-parametric protein maps reveal the spatial organization in early-developing human lung | |
| WildPose：一种长距离3D野生动物运动捕捉系统 | Muramatsu, N. | N/A | WildPose: A Long-Range 3D wildlife motion capture system | |
| 直接耦合分析与注意力机制 | Caredda, F. | N/A | Direct Coupling Analysis and The Attention Mechanism | |
| 开发用于研究合作行为的自动化拉取装置（MarmoAAP） | Meisner, O. C. | N/A | Development of a Marmoset Apparatus for Automated Pulling (MarmoAAP) to Study Cooperative Behaviors | |
| CD44促进了在空气介导的细胞间信号传导中的粘附相互作用。 | Bowman, R. L. | N/A | CD44 facilitates adhesive interactions in airineme-mediated intercellular signaling | |
| 小鼠胚胎发育过程中多条件和多模态时间剖面推断 | Zhang, R. | N/A | Multi-condition and multi-modal temporal profile inference during mouse embryonic development | |
| Vps5-Vps17 SNX-BAR蛋白与Retromer组装的分子基础 | Chen, K.-E. | N/A | Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer | |
| moPepGen：快速全面鉴定非规范肽段 | Zhu, C. | N/A | moPepGen: Rapid and Comprehensive Identification of Non-canonical Peptides | |
| 理解先前经验对疼痛感知和神经性疼痛影响的计算框架 | Ramne, M. | N/A | A Computational Framework for Understanding the Impact of Prior Experiences on Pain Perception and Neuropathic Pain | |
| 通过微调扩散模型精确生成固有无序蛋白质的构象集合 | Zhu, J. | N/A | Precise Generation of Conformational Ensembles for Intrinsically Disordered Proteins via Fine-tuned Diffusion Models | |
| 96孔聚丙烯酰胺凝胶用于电泳和Western印迹 | Birtwistle, M. R. | N/A | A 96-Well Polyacrylamide Gel for Electrophoresis and Western Blotting | |
| 性别分化与性二态性的共同演化 | Lesaffre, T. | N/A | The joint evolution of separate sexes and sexual dimorphism | |
| 揭示基因组复杂性：基因组图结构分析与优化变异检测工作流程的框架 | Kamaraj, V. | N/A | Unveiling Genomic Complexity: A Framework for Genome Graph Structural Analysis and Optimised Variant Calling Workflows | |
| 果蝇神经肌肉接头处的外周胶质细胞和神经元共同调节活动诱导的突触重塑 | Chang, Y.-C. | N/A | Peripheral glia and neurons jointly regulate activity-induced synaptic remodeling at the Drosophila neuromuscular junction | |
| 微生物代谢物引导的CAR T细胞工程通过表观遗传-代谢交叉对话增强抗肿瘤免疫 | Staudt, S. | N/A | Microbial metabolite-guided CAR T cell engineering enhances anti-tumor immunity via epigenetic-metabolic crosstalk | |
| 综合多模型分析肠道炎症揭示了临床前和临床炎症性肠病的关键分子特征 | Gonzalez Acera, M. | N/A | Integrated multi-model analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD | |
| 训练在动物园中对声音学习实验缺乏经验的港海豹参与发声学习实验 | Duengen, D. | N/A | Training Experimentally Naive Harbor Seals to Participate in Vocal Learning Experiments in a Zoo | |
| 编排不可能的化学：B12依赖型甲硫氨酸合成酶催化编排的结构快照 | Mendoza, J. | N/A | Orchestrating Improbable Chemistries: Structural Snapshots of B12-Dependent Methionine Synthase's Catalytic Choreography | |
| 胆碱能信号通过不同方式调节鸣禽的鸣唱前运动回路，以稳定鸣唱。 | Xu, N. | N/A | Cholinergic signaling differentially regulates song premotor circuits to stabilize songs in songbirds | |
| IL-6和IL-27负向调控与淋巴驱动性滑膜炎相关的CRTAM表达CD4+ T细胞。 | Derrac Soria, A. | N/A | IL-6 and IL-27 negatively regulate CRTAM-expressing CD4+ T-cells associated with lymphoid-driven synovitis. | |
| 人类和蝙蝠基因组在COSMIC突变特征下的稳健性 | Song, J.-H. | N/A | Human and bats genome robustness under COSMIC mutational signatures | |
| 通过拓扑约束分子生成模型发现新型喹啉类木瓜蛋白酶样蛋白酶抑制剂用于COVID-19 | Shang, J. | N/A | Discovery of novel quinoline papain-like protease inhibitors for COVID-19 through topology constrained molecular generative model | |
| HIV Vpr激活了一种核仁特异性的ATR通路，以降解核仁应激传感器CCDC137 | Nisson, K. A. | N/A | HIV Vpr activates a nucleolar-specific ATR pathway to degrade the nucleolar stress sensor CCDC137 | |
| 解锁隐藏噬菌体多样性，以完成BASEL收藏，系统探索噬菌体-宿主相互作用 | Humolli, D. | N/A | Unlocking hidden phage diversity to complete the BASEL collection for systematic exploration of phage-host interactions | |
| 炎症通过重塑骨髓微环境中的特定区域来干扰造血功能。 | Swann, J. W. | N/A | Inflammation perturbs hematopoiesis by remodeling specific compartments of the bone marrow niche | |
| 单层和双层中脂质动力学精确建模的挑战 | Tempra, C. | N/A | Challenges in the Accurate Modelling of Lipid Dynamics in Monolayers and Bilayers | |
| ADPKD 变异体在 PKD2 孔螺旋中导致门结构塌陷和不同形式的通道功能障碍。 | Palomero, O. E. | N/A | ADPKD variants in the PKD2 pore helix cause structural collapse of the gate and distinct forms of channel dysfunction. | |
| 综合分子动力学模拟解析交联数据，揭示线粒体蛋白质分布 | Schuhmann, F. | N/A | Integrative Molecular Dynamics Simulations Untangle Cross-Linking Data to Unveil Mitochondrial Protein Distributions | |
| G3BP1通过负调控MYD88-ARNO-ARF6信号通路维持血管内皮屏障的完整性。 | Wen, B. | N/A | G3BP1 Maintains Vascular Endothelial Barrier Integrity by Negatively Regulating the MYD88-ARNO-ARF6 Signaling Pathway | |
| 生长素高亮荧光的发展 | Aoyama, T. | N/A | Development of bright fluorescent auxin | |
| HCV感染中病毒适应性和适应性免疫反应的时间动态 | Walker, M. R. | N/A | Temporal dynamics of viral fitness and the adaptive immune response in HCV infection | |
| 系统综述与荟萃分析：欧盟地区Hyalomma marginatum蜱的脊椎动物宿主 | Bah, M. T. | N/A | Systematic review and meta-analysis of Hyalomma marginatum vertebrate hosts in the EU | |
| 欺凌与早期大脑发育：一项从青少年到成年早期的纵向结构磁共振成像研究 | Connaughton, M. | N/A | Bullying and Early Brain Development: A Longitudinal Structural Magnetic Resonance Imaging Study from Adolescence to Early Adulthood | |
| 阴道微生物群作为早产预测指标：一项观察性队列研究 | Lesimple, L. | N/A | Vaginal microbiota as a predictor of preterm birth: an observational cohort study | |
| 针对牛繁殖失败相关病原体的靶向综合下一代测序面板，实现病原体的同步检测 | Periyasamy, D. | N/A | Targeted syndromic next-generation sequencing panel for simultaneous detection of pathogens associated with bovine reproductive failure | |
| 不同用途温带玉米杂交种在不同环境下的核权重和源/汇比确定 | Chazarreta, Y. D. | N/A | Kernel weight and source/sink ratio determination of temperate maize hybrids with different end uses under contrasting environments | |
| 念珠菌（Candida albicans）与粪肠球菌（Enterococcus faecalis）之间的跨物种协同宿主细胞损伤 | Kapitan, M. | N/A | Synergistic cross-kingdom host cell damage between Candida albicans and Enterococcus faecalis | |
| 在pre-mRNA的3'-非翻译区，剪接位点的异质性调控基因表达 | Shaji, F. | N/A | Cleavage site heterogeneity at the pre-mRNA 3'-untranslated region regulates gene expression | |
| 巨噬细胞衍生的RNAseT2通过SLK/N-WASP/肌动蛋白束促进肌肉干细胞融合 | Weiss-Gayet, M. | N/A | Macrophage-derived RNAseT2 stimulates muscle stem cell fusion via SLK/N-WASP/actin bundling | |
| 连接组上的扩散小波：利用图扩散小波定位介导结构-功能映射的扩散源 | Jain, C. S. | N/A | Diffusion Wavelets on Connectome: Localizing the Sources of Diffusion Mediating Structure-Function Mapping Using Graph Diffusion Wavelets | |
| DRED：一个综合性的与重复扩展疾病相关的基因数据库 | Shi, Q. | N/A | DRED: A Comprehensive Database of Genes Related to Repeat Expansion Diseases | |
| 肝细胞中的胰高血糖素受体（GCGR）对于结构上与双重GCGR/GLP1R激动剂survodutide相关的类似物在体重减轻方面的卓越效果是必需的。 | Long, F. | N/A | Hepatic GCGR is required for the superior weight loss effects of a structurally related analogue of the dual GCGR/GLP1R agonist survodutide | |
| 受控检索依赖于语义控制区域与视觉皮层之间的定向交互作用：来自振荡动力学的MEG证据 | Eisenhauer, S. | N/A | Controlled retrieval relies on directed interactions between semantic control regions and visual cortex: MEG evidence from oscillatory dynamics | |
| 肩胛间棕色脂肪组织的交感神经支配并非雄性饮食诱导肥胖大鼠中OT引发体重增加和脂肪减少的主要介质。 | Edwards, M. M. | N/A | Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats | |
| RBBP5通过表观遗传调控全局蛋白质稳态动力学，确保哺乳动物机体健康 | Kubra, S. | N/A | Epigenetic regulation of global proteostasis dynamics by RBBP5 ensures mammalian organismal health | |
| 高尔基体相关微管交联蛋白MTCL2促进小脑颗粒神经元树突的多极延伸。 | Minekawa, M. | N/A | The Golgi-associated microtubule cross-linking protein MTCL2 promotes the multipolar extension of dendrites in cerebellar granule neurons. | |
| 细胞质中的核糖体搭乘线粒体前往树突 | Renken, C. J. | N/A | Cytoplasmic ribosomes hitchhike on mitochondria to dendrites | |
| 早期将初级肌管与次级肌管及成体肌肉干细胞分隔开来。 | Toulouse, G. | N/A | Early lineage segregation of primary myotubes from secondary myotubes and adult muscle stem cells. | |
| 水牛在发情期和间情期之间无细胞唾液miRNA谱的比较 | CHANDEL, R. | N/A | Comparative cell free salivary miRNA profile in Bubalus bubalis between diestrus and estrus stages | |
| 对野化与本地捕食者组合的增补、可替代及拮抗性猎物反应 | St. Juliana, J. R. | N/A | Additive, substitutable, and antagonistic prey responses to feral and native predator combinations | |
| 一种通过计算指导的方法来提高VHH结合剂的表达 | OZDEMIR, E. S. | N/A | A computationally guided approach to improve expression of VHH binders | |
| 具有可逆热离子交联的3D水凝胶功能性人唾液腺泡细胞球状体的扩展 | Munguia-Lopez, J. G. | N/A | Expansion of functional human salivary acinar cell spheroids with reversible thermo-ionically crosslinked 3D hydrogels | |
| 染色质三色单分子定位显微镜 | Acosta, N. | N/A | Three-color single-molecule localization microscopy in chromatin | |
| EmbSAM：用于快速发育胚胎图像的细胞边界定位与分割任意模型 | Zhao, C. | N/A | EmbSAM: Cell boundary localization and Segment Anything Model for fast images of developing embryos | |
| CNValidatron，利用计算机视觉实现CNV调用的自动化验证 | Montalbano, S. | N/A | CNValidatron, automated validation of CNV calls using computer vision | |
| bayesReact：表达耦合的调控基序分析在癌症和单细胞水平检测微RNA活性 | Rasmussen, A. M. | N/A | bayesReact: Expression-coupled regulatory motif analysis detects microRNA activity in cancer and at the single cell level | |
| niiv: 快速自监督神经隐式各向同性体积重建 | Troidl, J. | N/A | niiv: Fast Self-supervised Neural ImplicitIsotropic Volume Reconstruction | |
| 从谱系追踪数据推断细胞分化图谱 | Sashittal, P. | N/A | Inferring cell differentiation maps from lineage tracing data | |
| Montijano-Bergues-Bory-Gompertz随机模型中未受干扰肿瘤生长的参数估计 | Bonilla-Capilla, B. | N/A | Parameter estimation in the Montijano-Bergues-Bory-Gompertz stochastic model for unperturbed tumor growth | |
| 白血病衍生的apelin选择内皮龛克隆以促进肿瘤发生 | Baron, C. S. | N/A | Leukemia-derived apelin selects endothelial niche clones to promote tumorigenesis | |
| PROX1对细胞命运可塑性的主动抑制保障了肝细胞的特性，并防止了肝癌的发生。 | Lim, B. | N/A | Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumourigenesis | |
| 顺序使用ATR和PARP抑制剂克服胰腺导管腺癌中获得的DNA损伤剂抗性 | Herbert, K. J. | N/A | Sequential ATR and PARP Inhibition Overcomes Acquired DNA Damaging Agent Resistance in Pancreatic Ductal Adenocarcinoma | |
| GCN2在整合应激反应之外的作用：防止过度核糖体生物合成和mRNA翻译 | Roman-Trufero, M. | N/A | An integrated stress response-independent role of GCN2 prevents excessive ribosome biogenesis and mRNA translation | |
| 线粒体代谢是结直肠癌化疗敏感性的关键决定因素 | Moss, D. Y. | N/A | Mitochondrial metabolism is a key determinant of chemotherapy sensitivity in Colorectal Cancer | |
| 梅克尔细胞癌衍生的巨噬细胞迁移抑制因子（MIF）可能促进慢性淋巴细胞白血病的持续存在。 | Alencar, G. F. | N/A | Merkel cell carcinoma-derived macrophage migration inhibitory factor (MIF) may promote persistence of Chronic Lymphocytic Leukemia | |
| 进化获得了一种原始的光依赖性核重定位现象，这种现象在地钱（Marchantia polymorpha）中被观察到。 | Iwabuchi, K. | N/A | Evolutionary acquisition of a primitive light-dependent nuclear relocation in Marchantia polymorpha | |
| 抗体亲和力的提高及利用PURE核糖体展示和微生物分泌系统 | Kihara, M. | N/A | Improvement of Antibody Affinity and Using PURE Ribosome Display and Microbial Secretion System | |
| RoCi - 基于滚环复制的单步多拷贝整合系统 | Antsotegi-Uskola, M. | N/A | RoCi - A Single Step Multi-Copy Integration System Based on Rolling-Circle Replication | |
| 基于BEN的预测建模（BPM）进行表型预测 | Song, D. | N/A | Phenotype Prediction Using BEN-Based Predictive Modeling (BPM) | |
| 斑马鱼幼体感觉运动反应的发育：野生型与GCaMP6s转基因品系的比较 | Caperaa, M. | N/A | Development of sensorimotor responses in larval zebrafish: a comparison between wild-type and GCaMP6s transgenic line | |
| 利用结构方程模型预测静态和动态听觉图形-背景分析中的噪音中言语能力 | Guo, X. | N/A | Predicting speech-in-noise ability with static and dynamic auditory figure-ground analysis using structural equation modelling | |
| 灵长类上丘对暗对比的微扫视前敏感性增强更强 | Wu, W. | N/A | Stronger premicrosaccadic sensitivity enhancement for dark contrasts in the primate superior colliculus | |
| PSEN1突变通过破坏受调控的细胞内蛋白水解作用，使家族性阿尔茨海默病中的星形胶质细胞模型易发炎症。 | Ziff, O. J. | N/A | Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer's disease through disrupted regulated intramembrane proteolysis | |
| 在海马体循环网络模型中，条形码活动能够实现高效的记忆绑定。 | Fang, C. | N/A | Barcode activity in a recurrent network model of the hippocampus enables efficient memory binding | |
| M3毒蕈碱乙酰胆碱受体对人类记忆辅助性T细胞炎症特征的调节作用 | Gholizadeh, F. | N/A | Modulatory Effects of M3 Muscarinic Acetylcholine Receptor on Inflammatory Profiles of Human Memory T Helper Cells | |
| 非经典白介素-22受体信号在真菌免疫监视期间重塑黏膜屏障 | Millet, N. | N/A | Non-canonical IL-22 receptor signaling remodels the mucosal barrier during fungal immunosurveillance | |
| 枯萎的野花和沮丧的蜜蜂：气候变化威胁美国州象征 | Ge, X. | N/A | Wilting Wildflowers and Bummed-Out Bees: Climate Change Threatens U.S. State Symbols | |
| 在多菌株接种中，苜蓿共生基因的突变为根瘤菌中自然发生的遗传变异创造了复杂的选择环境。 | Guha, S. | N/A | In multi-strain inoculations, mutation of Medicago symbiosis genes creates a complex selective landscape for naturally-occurring genetic variation in rhizobia | |
| 注意极地太阳：尽管空气温度相对较低，太阳辐射仍频繁引发繁殖中的王企鹅的热应激。 | Noiret, A. | N/A | Mind the polar sun: Solar radiations trigger frequent heat stress in breeding king penguins, despite relatively cool air temperatures. | |
| 胰腺疾病风险相关增强子的预测优先级 | Wang, L. | N/A | Predictive Prioritization of Enhancers Associated with Pancreas Disease Risk | |
| 一种占卜鼠尾草（Salvia divinorum）的染色体级别参考基因组为萨维诺林A的生物合成提供了深入见解。 | Ford, S. A. | N/A | A chromosome level reference genome of Diviners sage (Salvia divinorum) provides insight into salvinorin A biosynthesis | |
| 手势交流的特异性：巴巴利猕猴（Macaca sylvanus）拍手行为的个案研究 | Bosshard, T. C. | N/A | Idiosyncrasy in gestural communication: a case study of hand-clapping in a Barbary macaque (Macaca sylvanus) | |
| 尼古丁与阿尔法辐射诱导的DNA损伤相互作用，这可能有助于在人类肺上皮细胞中进行错误的修复。 | Boroumand, N. | N/A | Nicotine interacts with DNA lesions induced by alpha radiation which may contribute to erroneous repair in human lung epithelial cells | |
| 喷墨打印的石墨烯多电极阵列：一种适用于体外心脏电生理学的可及平台 | Lumpuy-Castillo, J. | N/A | Inkjet-printed graphene multielectrode arrays: an accessible platform for in vitro cardiac electrophysiology | |
| Novae：一种基于图的空间转录组学数据基础模型 | Blampey, Q. | N/A | Novae: a graph-based foundation model for spatial transcriptomics data | |
| 基于系统发育的代表性变异体选择与Navargator：使用两个免疫研究中的体液交叉反应数据验证原理 | Curran, D. M. | N/A | Phylogeny-based selection of representative variants with Navargator: Proof of principle using humoral cross-reactivity data from two immunization studies | |
| G2PDeep-v2：一种基于网络的深度学习框架，用于利用多组学数据进行表型预测和生物标志物发现 | Zeng, S. | N/A | G2PDeep-v2: a web-based deep-learning framework for phenotype prediction and biomarker discovery using multi-omics data | |
| BEGAN：基于玻尔兹曼加权数据增强的增强型GAN用于昆虫信息素受体中的分子设计 | Dai, J. | N/A | BEGAN: Boltzmann-Reweighted Data Augmentation for Enhanced GAN-Based Molecule Design in Insect Pheromone Receptors | |
| Pyjacker识别出急性髓系白血病中的增强子劫持事件，包括通过删除7q激活MNX1。 | Sollier, E. | N/A | Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q | |
| DNA损伤应答缺陷增强神经母细胞瘤进展并提高对PARP和ATR联合抑制的敏感性 | Hayes, M. N. | N/A | DNA Damage Response Deficiency Enhances Neuroblastoma Progression and Sensitivity to Combination PARP and ATR Inhibition | |
| 高效发现非底物型共价抑制剂及其与S-腺苷甲硫氨酸脱羧酶的结构-活性关系分析 | Ai, Y. | N/A | High-efficiency discovery and structure-activity-relationship analysis of non-substrate-based covalent inhibitors of S-adenosylmethionine decarboxylase | |
| 小鼠远端输卵管中多纤毛细胞的与衰老相关的空泡化反映了独特的细胞身份和管腔微环境。 | Harwalkar, K. | N/A | Aging-associated vacuolation of multi-ciliated cells in the distal mouse oviduct reflects unique cell identity and luminal microenvironment | |
| 霜霉病菌效应蛋白HaRxL106与转录因子BIM1相互作用，改变植物生长、油菜素内酯信号传导及对病原体的易感性。 | Bogino, M. F. | N/A | Downy mildew effector HaRxL106 interacts with the transcription factor BIM1 altering plant growth, BR signaling and susceptibility to pathogens | |
| 拟南芥组蛋白H3K4me3结合的ALFIN样蛋白介导组蛋白H2A的泛素化，并协调多种染色质修饰。 | Su, X.-M. | N/A | The Arabidopsis histone H3K4me3-binding ALFIN-like proteins mediate histone H2A ubiquitination and coordinate diverse chromatin modifications | |
| 利用大型语言模型进行代谢工程设计 | Li, X. | N/A | Leveraging large language models for metabolic engineering design | |
| 鱼类中的微量元素：生物累积评估及其相关健康风险。 | Naz, S. | N/A | Trace Elements in Fish: Assessment of bioaccumulation and associated health risks. | |
| 禁食对热应激肉鸡的影响：第一部分——生长性能、肉质、肠道组织形态学和微生物反应 | Ahmed, T. | N/A | Effects of fasting on heat-stressed broiler chickens: part I- growth performance, meat quality, gut histomorphological and microbial responses | |
| 神经营养因子artemin及其受体GFRα3通过离子通道TRPM8介导偏头痛样疼痛。 | Yang, C. | N/A | The neurotrophin artemin and its receptor GFRα3 mediate migraine-like pain via the ion channel TRPM8 | |
| 情境性恐惧表达的性别差异与内侧前额叶皮层活动的改变有关 | Vazquez, K. | N/A | Sex differences in contextual fear expression are associated with altered medial prefrontal cortex activity | |
| 背侧下丘中听觉空间的人口编码在双耳线索改变的情况下仍然存在 | Rogalla, M. M. | N/A | Population coding of auditory space in the dorsal inferior colliculus persists with altered binaural cues | |
| 多种感觉剥夺对内侧内嗅皮层空间编码细胞的不同影响 | Tian, J. | N/A | Differential Impact of Multiple Sensory Deprivation on Spatial-coding Cells in Medial Entorhinal Cortex | |
| 爆裂放电通过电感觉神经群体优化了自然通信信号的不变编码 | Metzen, M. G. | N/A | Burst firing optimizes invariant coding of natural communication signals by electrosensory neural populations | |
| 针对α-突触核蛋白的病毒编码单链抗体片段可保护小鼠免受突触核蛋白病模型中的运动障碍和神经病理学损害 | Castonguay, A.-M. | N/A | Virally encoded single-chain antibody fragments targeting alpha-synuclein protect against motor impairments and neuropathology in a mouse model of synucleinopathy | |
| IL-1b介导的角膜上皮细胞免疫代谢适应 | Sanches, J. M. | N/A | IL-1b-mediated Immunometabolic Adaptation in Corneal Epithelial Cells | |
| 脑膜炎球菌疫苗Bexsero能引发强大的细胞免疫反应，这种反应针对的是但并不总是能保护小鼠在阴道感染期间免受淋病奈瑟菌的侵害。 | Zeppa, J. J. | N/A | Meningococcal vaccine Bexsero elicits a robust cellular immune response that targets but is not consistently protective against Neisseria gonorrhoeae during murine vaginal infection | |
| IFT和BBSome蛋白对于墨西哥利什曼原虫的致病性是必需的，但鞭毛运动是非必需的。 | Beneke, T. | N/A | IFT and BBSome proteins are required for Leishmania mexicana pathogenicity, but flagellar motility is dispensable | |
| 对小农户水稻种植者的成本效益分析显示，现有的施肥方式严重损害了他们的收入。 | Chen, J. | N/A | Cost-benefit analysis across smallholder rice farmers reveals that existing fertilization practices severely compromise their income | |
| 化石多样化速率的表观时间缩放是由采样偏差引起的。 | Reijenga, B. R. | N/A | Apparent timescaling of fossil diversification rates is caused by sampling bias | |
| 洞穴作为物种泵：关键创新、隔离与周期性基因渗入驱动动态喀斯特景观中世界最大洞穴鱼辐射 | Mao, T. | N/A | Caves as species pumps: key innovations, isolation, and periodic introgression drive the world's largest cavefish radiation in a dynamic karstic landscape | |
| 一种新生F-box基因通过选择性降解磷酸葡萄糖变位酶阻断种间杂交中的基因流动 | Xie, D. | N/A | A Newborn F-box Gene Blocks Gene Flow by Selectively Degrading Phosphoglucomutase in Species Hybrids | |
| 强选择，但低重复性：温度对适应性基因组预测的特定影响 | Rego, A. | N/A | Strong Selection, but low repeatability: Temperature-specific effects on genomic predictions of adaptation | |
| 性染色体上癌症基因的体细胞进化 | Marco, A. | N/A | Somatic evolution of cancer genes in sex chromosomes | |
| 单倍体型解析基因组为研究双壳类基因组多样性的起源和功能提供了见解 | Liu, S. | N/A | Haplotype-resolved genomes provide insights into the origin and function of genome diversity in bivalves | |
| METTL3通过Akt/mTOR通路调节辐射诱导的心脏纤维化 | Gu, X.-s. | N/A | METTL3 Modulates Radiation-Induced Cardiac Fibrosis via the Akt/mTOR Pathway | |
| 通过抑制帽依赖性起始，NRF2翻译阻断增强了淋巴瘤细胞对铁死亡和CAR-T免疫疗法的敏感性。 | Manara, P. | N/A | NRF2 translation block by inhibition of cap-dependent initiation sensitizes lymphoma cells to ferroptosis and CAR-T immunotherapy | |
| 对拟南芥中影响叶片毛状体发育和表皮金属积累的基因进行全基因组关联筛选 | Bezvoda, R. | N/A | A genome-wide association screen for genes affecting leaf trichome development and epidermal metal accumulation in Arabidopsis | |
| 程序性细胞死亡和气孔密度调控花药在环境湿度变化下的开裂 | Kampova, A. | N/A | Programmed cell death and stomatal density regulate anther opening in response to ambient humidity | |
| 乙烯通过ERF5-褪黑素-ERF104途径增强VvMYB14表达，从而调节葡萄籽中的苯丙烷途径 | Gao, S. | N/A | Ethylene Modulates the Phenylpropanoid Pathway by Enhancing VvMYB14 Expression via the ERF5-Melatonin-ERF104 Pathway in Grape Seeds | |
| 一种内源性多肽PEP2调节拟南芥中的铁缺乏信号传导和根系生长。 | Shikha, D. | N/A | An endogenous peptide PEP2 modulates Iron-deficiency signalling and root growth in Arabidopsis. | |
| 重新审视Vellozia Vand.的细胞遗传学：KLN1的免疫定位阐明了该属的染色体数目 | Braz, G. T. | N/A | Revisiting the cytogenetics of Vellozia Vand.: immunolocalization of KLN1 elucidates the chromosome number for the genus | |
| 气候大脑 - 问卷、任务与神经影像数据集 | Zaremba, D. A. | N/A | CLIMATE BRAIN - Questionnaires, Tasks and the Neuroimaging Dataset | |
| 中性粒细胞NADPH氧化酶打破炎症IL-1β/IL-17A循环，以增强呼吸道病毒感染期间的病原体清除。 | Sofoluwe, A. | N/A | Neutrophil NADPH oxidase breaks the inflammatory IL-1beta/IL-17A circuit to enhance pathogen clearance during respiratory virus infections. | |
| 孤儿核受体NR4A3对于驻留记忆CD8+ T细胞的生成并非必需。 | Odagiu, L. | N/A | The orphan nuclear receptor NR4A3 is dispensable for resident memory CD8+ T cell generation | |
| 通过抑制髓源性抑制细胞中的PI3K-gamma信号通路，预防手术引起的免疫抑制和转移。 | Angka, L. | N/A | Preventing surgery induced immune suppression and metastases by inhibiting PI3K-gamma signalling in Myeloid-Derived Suppressor Cells. | |
| IL-34通过赋予调节性T细胞新的非经典功能，在神经炎症期间保护脑屏障的完整性。 | Van Hoecke, L. | N/A | IL-34 empowers regulatory T cells with novel non-canonical function to safeguard brain barrier integrity during neuro-inflammation. | |
| 检测粪菌移植后的微生物定植：利用安慰剂测序和培养富集的宏基因组学方法从噪声中筛选信号 | Shekarriz, S. | N/A | Detecting microbial engraftment after FMT: sorting signals from noise using placebo sequencing and culture-enriched metagenomics | |
| 对入侵的大黄蜂（Bombus terrestris）进行全景观的宏条形码分析显示，肠道微生物组与花粉微生物组之间存在相互作用。 | Haque, S. | N/A | Landscape-wide metabarcoding of the invasive bumblebee (Bombus terrestris) shows interactions among the gut microbiome and pollenbiome | |
| 在野生和圈养的狐猴中，口腔微生物群的恢复力和头发微生物群在宿主环境中的不稳定性 | Burten, R. B. | N/A | The resilience of the oral microbiome and lability of the hair microbiome across host environments in wild and captive lemurs | |
| 欧洲旧石器时代晚期人口对气候变化的反应 | Schmidt, I. | N/A | Demographic responses to climatic changes during the Final Palaeolithic in Europe | |
| 氮对沙丘石楠生态系统中Calluna vulgaris和Avenella flexuosa生长的影响：竞争与频率依赖性 | Damgaard, C. | N/A | The effect of nitrogen on the growth of Calluna vulgaris and Avenella flexuosa in a dune heath ecosystem: competition and frequency-dependence | |
| 中欧永久农业的作物生产力介于有机农业和传统农业之间。 | Reiff, J. | N/A | Crop productivity of Central European Permaculture is within the range of organic and conventional agriculture. | |
| 上下文和性别依赖的父本性成功与后代病原体抵抗力之间的联系 | Liao, A. | N/A | Context- and sex-dependent links between sire sexual success and offspring pathogen resistance | |
| 饥饿时间决定其对果蝇雌性感染易感性的影响，与宿主进化历史无关 | Basu, A. | N/A | Timing of starvation determines its effects on susceptibility to infection in Drosophila melanogaster females independent of host evolutionary history | |
| 高分辨率离子迁移分离与信使标记红外光谱联用平台的发展及其在精准结构表征中的应用 | Harrilal, C. | N/A | Development of a Platform for High-Resolution Ion Mobility Separations Coupled with Messenger Tagging Infrared Spectroscopy for High-Precision Structural Characterizations | |
| genomesizeR：一个用于基因组大小预测的R包 | Mercier, C. | N/A | genomesizeR: An R package for genome size prediction | |
| 番茄和茄子幼苗茎部因感染Ralstonia pseudosolanacearum F1C1而出现的软化和半透明形态特征 | Bhuyan, S. | N/A | Morphology of softening and translucency in the stems of tomato and eggplant seedlings due to infection by Ralstonia pseudosolanacearum F1C1 | |
| 利用植硅体分析区分野生和驯化埃塞俄比亚香蕉（芭蕉科） | Castillo Cobo, C. | N/A | Differentiating wild and domesticated enset (Musaceae) using phytolith analysis | |
| ElixirSeeker：一种利用注意力驱动融合分子指纹的机器学习框架，用于发现抗衰老化合物 | Pan, Y. | N/A | ElixirSeeker: A Machine Learning Framework Utilizing Attention-Driven Fusion of Molecular Fingerprints for the Discovery of Anti-Aging Compounds | |
| 一种可扩展的代谢组学绝对定量方法 | Ferro, L. S. | N/A | A scalable approach to absolute quantitation in metabolomics | |
| 蝙蝠听觉中脑中发声自我监测的神经表征 | Ye, H. | N/A | Neural representation of vocalization self-monitoring in the bat auditory midbrain | |
| LM11a-31抑制p75神经营养素受体（p75NTR）的切割，并在帕金森病细胞培养模型中具有神经保护作用。 | Pokharel, P. V. | N/A | LM11a-31 Inhibits p75 Neurotrophin Receptor (p75NTR) Cleavage and is Neuroprotective in a Cell Culture Model of Parkinson's Disease. | |
| 超越免疫：疟原虫对蚊子代谢途径调控的转录组全景图 | Garcia-Longoria, L. | N/A | Beyond immunity: a transcriptomic landscape of Plasmodium's modulation of mosquito metabolic pathways | |
| 将濒危的萨瓦纳树种Firmina major的基因组组装起来，这种树种是中国特有的。 | Yang, J. | N/A | Genome assembly of Firmina major, an endangered savanna tree species endemic to China | |
| START域从单一网络结构中生成特定旁系同源基因的调控网络 | Holub, A. S. | N/A | START domains generate paralog-specific regulons from a single network architecture | |
| 对四种小鼠器官中基因、长链非编码RNA和转座子转录模式的调查揭示了共享和器官特异性的性别偏倚调控 | Zhuang, Q. K.-W. | N/A | Survey of gene, lncRNA and transposon transcription patterns in four mouse organs highlights shared and organ-specific sex-biased regulation | |
| 流感人类T细胞反应的目标大多在H5N1中保持保守。 | Sidney, J. | N/A | Targets of influenza Human T cell response are mostly conserved in H5N1 | |
| 宿主年龄和营养如何影响专性共生菌与兼性共生菌的密度调控？来自采采蝇的启示 | Whittle, M. | N/A | How does host age and nutrition affect density regulation of obligate versus facultative bacterial symbionts? Insights from the tsetse fly | |
| 壳外世界：温度如何塑造两种近缘海洋蜗牛的遗传变异 | Wuitchik, D. M. | N/A | Outside your shell: how temperature shapes genetic variation in two species of congeneric marine snails | |
| 用于鲑鱼生态系统监测的eDNA采样系统 | Deeg, C. M. | N/A | eDNA sampling systems for salmon ecosystem monitoring | |
| 实现具有生理运动补偿的真实三维扩散成像 | Wang, Y. | N/A | Towards genuine three-dimensional diffusion imaging with physiological motion compensation | |
| 血液-脑屏障类器官的高级组织技术作为药物开发中的高通量毒性检测手段 | Bell, L. | N/A | Advanced Tissue Technologies of Blood-Brain Barrier Organoids as High Throughput Toxicity Readouts in Drug Development | |
| 静息状态脑电图固有神经时间尺度的重测信度 | Tang, X. | N/A | Test-retest reliability of resting-state EEG intrinsic neural timescales | |
| 在7特斯拉磁场下使用31P-MRS对小鼠大脑中肌酸激酶动力学进行体内定量研究 | Tachrount, M. | N/A | In vivo quantification of creatine kinase kinetics in mouse brain using 31P-MRS at 7 Tesla | |
| 从第一性原理理解髓鞘化比率，其推导、用途及伪影 | Gow, A. | N/A | Understanding The Myelin g ratio From First Principles, Its Derivation, Uses And Artifacts | |
| 背侧中缝5-羟色胺神经元内在动力学对长程输入的功能性分离 | Lynn, M. B. | N/A | Functional separation of long-range inputs by intrinsic dynamics of dorsal raphe 5-HT neurons | |
| 呼吸对反应速度和准确性产生了系统性的时间滞后影响。 | Harting, C. | N/A | Respiration shapes response speed and accuracy with a systematic time lag | |
| 利用具有图案化亲水斑块的双亲性微粒实现可调的皮升级液滴形成 | Song, X. | N/A | Tunable picoliter-scale dropicle formation using amphiphilic microparticles with patterned hydrophilic patches | |
| Doblin：从DNA条形码时间序列中推断占优势的克隆谱系 | Serohijos, A. | N/A | Doblin: Inferring dominant clonal lineages from DNA barcoding time-series | |
| RNAi药物在快速分裂细胞中的结构-沉默持续时间关系 | Kremer, A. | N/A | Structure - silencing duration relationships in RNAi medicines in rapidly dividing cells | |
| Mouse-Geneformer：一种用于小鼠单细胞转录组的深度学习模型及其跨物种应用 | Shigenobu, S. | N/A | Mouse-Geneformer: A Deep Learning Model for Mouse Single-Cell Transcriptome and Its Cross-Species Utility | |
| 时间生物学节律对中枢神经系统中特定部位和细胞的miRNA和mRNA基因及网络的调控 | Zacharias, A. M. | N/A | Chronobiological rhythms control of site- and cell-specific miRNA and mRNA genes and networks across the central nervous system | |
| 单价XBB.1.5 mRNA疫苗比二价WT/BA.5 mRNA疫苗更能持久且协调地引发对SARS-CoV-2刺突蛋白的抗体反应。 | Barouch, S. E. | N/A | Monovalent XBB.1.5 mRNA Vaccine Recalls a More Durable and Coordinated Antibody Response to SARS-CoV-2 Spike than the Bivalent WT/BA.5 mRNA Vaccine | |
| 人表面活性蛋白A变异体的差异性免疫调节决定了SARS-CoV-2诱导的肺病严重程度 | Jacob, I. B. | N/A | Differential Immunoregulation by Human Surfactant Protein A Variants Determines Severity of SARS-CoV-2-induced Lung Disease | |
| 细菌基因组编码的ParMs | Ali, S. | N/A | Bacterial genome encoded ParMs | |
| 鉴定出一种调节免疫反应的真菌抗菌内肽酶 | Machata, S. | N/A | Identification of a fungal antibacterial endopeptidase that modulates immune responses | |
| 噬菌体间的竞争和生物膜降低了两种烈性噬菌体联合对抗铜绿假单胞菌的效力 | Buerkle, M. | N/A | Phage-phage competition and biofilms reduce the efficacy of a combination of two virulent bacteriophages against Pseudomonas aeruginosa | |
| 铜绿假单胞菌表面行为中PilU的作用 | Zhang, J. | N/A | The role of PilU in the surface behaviors of Pseudomonas aeruginosa | |
| 弓形虫转录因子AP2XII-8：G1期进展和寄生虫分裂的关键调控因子 | Shi, Y. | N/A | Toxoplasma gondii transcription factor AP2XII-8: a key regulator of G1 phase progression and parasite division | |
| 卷曲乳杆菌S层蛋白调节女性下生殖道先天免疫反应和炎症。 | Decout, A. | N/A | Lactobacillus crispatus S-layer proteins modulate innate immune response and inflammation in the lower female reproductive tract. | |
| LolA 和 LolB 在拟杆菌门中是保守的，对滑动运动和IX型分泌系统至关重要。 | De Smet, T. | N/A | LolA and LolB are conserved in Bacteroidetes and are crucial for gliding motility and Type IX secretion. | |
| 在人类原代心脏内皮细胞中，基孔肯雅病毒的差异限制发生在病毒生命周期的多个步骤。 | Spector, S. N. | N/A | Differential restriction of chikungunya virus in primary human cardiac endothelial cells occurs at multiple steps in the viral life cycle | |
| 鼻内接种表达Delta或Omicron B.1.1.529 SARS-CoV-2刺突蛋白的副流感病毒载体疫苗，可诱导黏膜和系统性免疫，并保护仓鼠免受同源和异源挑战。 | Park, H.-S. | N/A | Intranasal parainfluenza virus-vectored vaccine expressing SARS-CoV-2 spike protein of Delta or Omicron B.1.1.529 induces mucosal and systemic immunity and protects hamsters against homologous and heterologous challenge | |
| 凝聚蛋白环挤压特性、障碍物以及在酿酒酵母同源搜索中的作用 | Piveteau, V. | N/A | Condensin loop extrusion properties, roadblocks, and role in homology search in S. cerevisiae | |
| 开发一种DNA编码库筛选方法DEL Zipper，以增强对RNA靶向化学物质的研究 | Ma, Z. | N/A | Development of a DNA-encoded library screening method DEL Zipper to empower the study of RNA-targeted chemical matter | |
| 人肺基底细胞在SARS-CoV-2感染后释放的PROS1有助于上皮细胞修复并限制炎症。 | Simakou, T. | N/A | PROS1 released by human lung basal cells upon SARS-CoV-2 infection facilitates epithelial cell repair and limits inflammation. | |
| 参考样本的表观基因组、转录组和蛋白质组特征分析 | Nepal, C. | N/A | Epigenomic, transcriptomic and proteomic characterizations of reference samples | |
| 线粒体二羧酸载体在体内介导肝脏糖异生作用 | Pape, D. J. | N/A | The mitochondrial dicarboxylate carrier mediates in vivo hepatic gluconeogenesis | |
| 通过铁蛋白笼的超分子组装生成的磁性蛋白质聚集体——一种用于酶固定化的模块化策略 | Olcucu, G. | N/A | Magnetic Protein Aggregates Generated by Supramolecular Assembly of Ferritin Cages - A Modular Strategy for the Immobilization of Enzymes | |
| 使用基于肽的传感器直接测量生物膜中的PIP2密度 | Menon, V. K. | N/A | Direct measurement of PIP2 densities in biological membranes using a peptide-based sensor | |
| 目标条件扩散生成强效TNFR超家族拮抗剂和激动剂 | Gloegl, M. | N/A | Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists | |
| 玻璃态表面活性剂实现超高浓度生物治疗药物 | Jons, C. K. | N/A | Glassy Surfactants Enable Ultra-High Concentration Biologic Therapeutics | |
| 清醒大鼠胃运动的磁共振成像 | Wang, X. | N/A | Magnetic Resonance Imaging of Gastric Motility in Conscious Rats | |
| 从空间转录组数据中提取生物学相关的信号 | Radkevich, E. | N/A | Informing biologically relevant signal from spatial transcriptomic data | |
| iSeqsSearch：为iBlast/iMMSeqs2/iDiamond设计的增量蛋白质搜索工具 | Yoo, H. | N/A | iSeqsSearch: Incremental Protein Search for iBlast/iMMSeqs2/iDiamond | |
| CodonTransformer：一种使用上下文感知神经网络的多物种密码子优化器 | Fallahpour, A. | N/A | CodonTransformer: a multispecies codon optimizer using context-aware neural networks | |
| 计算癌症治疗的斯塔克伯格均衡 | Ganzfried, S. | N/A | Computing Stackelberg Equilibrium for Cancer Treatment | |
| 探测他人的存在：跨脑尺度的概率推断揭示了增强的兴奋性突触效能 | Esmaeili, A. | N/A | Probing other's Presence: Probabilistic Inference Across Brain Scales Reveals Enhanced Excitatory Synaptic Efficacy | |
| 认知与生活方式相关的老龄化人脑海马微结构变异 | Agyekum, T. | N/A | Cognitive-and lifestyle-related microstructural variation in the ageing human hippocampus | |
| 无监督的分段线性解码能够在多任务脑机接口中准确预测肌肉活动。 | Ma, X. | N/A | Unsupervised, piecewise linear decoding enables an accurate prediction of muscle activity in a multi-task brain computer interface | |
| 眼动控制中的努力：指令和奖励在时空眼动动力学中的作用 | Wolf, C. | N/A | Effort in Oculomotor Control: Role of Instructions and Reward on Spatio-temporal Eye Movement Dynamics | |
| 一种涉及双向耦合的外侧和内侧内嗅皮层层的统一模型，用于海马体空间和物体细胞 | Patil, B. K. | N/A | A unified model of hippocampal spatial and object cells involving bidirectionally coupled Lateral and Medial Entorhinal Cortical layers | |
| III型干扰素通过触发细胞死亡独立于STAT激活抑制甲型流感病毒感染 | Prus, W. | N/A | Type III interferons suppress influenza A virus infection independently of STAT activation by triggering cell death | |
| 计算代谢建模揭示了小鼠癌症恶病质期间肠道微生物群在代谢转变中的作用 | Moissl-Eichinger, C. | N/A | Computational metabolic modeling unveils gut microbiomes role in metabolic shifts during murine cancer cachexia | |
| 适用于快速培养乳酸杆菌（Lactobacillus iners）及其他阴道细菌的实用媒体配方 | Serrador, D. | N/A | Practical Media Formulations for Rapid Growth of Lactobacillus iners and Other Vaginal Bacteria | |
| 野生型驯化：在丰富培养基中，内在代谢特性的丧失被文化所掩盖 | Vezina, B. | N/A | Wild type domestication: loss of intrinsic metabolic traits concealed by culture in rich media | |
| 金合欢属植物（Acacia gerrardii），作为一种沙漠植物，是可持续获取具有抗菌特性的天然产品的来源。 | Elkahoui, S. | N/A | Acacia gerrardii, a desert plant as a sustainable source of natural products with antimicrobial properties | |
| 蛋白质-配体复合物中的质子化效应——以内酰胺蛋白酶和抑肽酶A为例，结合计算和实验方法进行研究 | Vatheuer, H. | N/A | Protonation effects in protein-ligand complexes - a case study of endothiapepsin and pepstatin A with computational and experimental methods | |
| DYF-5通过影响列车转向来调节鞭毛内运输 | Mul, W. | N/A | DYF-5 regulates intraflagellar transport by affecting train turnaround | |
| 一种基于纳米抗体的方法，用于在活细胞中捕获和可视化二元蛋白质复合物的相互作用 | Sleiman, N. H. | N/A | A nanobody-based approach to capture and visualize interactions of binary protein complexes in living cells | |
| 解码酵母热休克中的转录记忆及RNA结合蛋白Mip6的功能意义 | Rodriguez-Navarro, S. | N/A | Decoding Transcriptional Memory in Yeast Heat Shock and the Functional Implication of the RNA Binding Protein Mip6 | |
| 胞嘧啶-5 DNA甲基化介绍使细胞对氧化损伤敏感 | Krwawicz, J. | N/A | Introduction of cytosine-5 DNA methylation sensitizes cells to oxidative damage | |
| UM171和新生型癌症突变体的结构模拟物通过招募E3连接酶KBTBD4来共同选择HDAC1/2 | Chen, Z. | N/A | Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment | |
| 53BP1缺陷导致通过断裂诱导复制（BIR）进行超重组 | Shah, S. B. | N/A | 53BP1 deficiency leads to hyperrecombination using break-induced replication (BIR) | |
| 计算和报告基于DIA蛋白质组学的变异系数 | Brenes, A. J. | N/A | Calculating and Reporting Coefficients of Variation for DIA-based Proteomics | |
| 2.5埃分辨率下酵母ADP-肌动蛋白丝的冷冻电镜重建。与哺乳动物和禽类F-肌动蛋白的比较。 | Stevenson, S. R. | N/A | CryoEM Reconstruction of Yeast ADP-Actin Filament at 2.5 Angstrom resolution. A comparison with mammalian and avian F-actin. | |
| 通过明胶-弹性纤维增强水凝胶进行阴道组织工程 | Zambuto, S. G. | N/A | Vaginal Tissue Engineering via Gelatin-Elastin Fiber-Reinforced Hydrogels | |
| 材料成分和植入部位影响体内设备降解速率 | Pawelec, K. | N/A | Material Composition and Implantation Site Affect in vivo Device Degradation Rate | |
| 通过考虑树突计算来克服运动传感器模型的局限性 | Luna, R. | N/A | Overcoming the limitations of motion sensor models by considering dendritic computations | |
| 一种来自天门冬科植物的新型Polerovirus，其RNA沉默抑制蛋白P0定义了该病毒的种类。 | Dekker, R. J. | N/A | A new Polerovirus species in plants from the Asparagaceae family defined by its RNA-silencing repressor protein P0 | |
| # BioRxiv 2024-09-12 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 双色光对神经元的高时间精度激活和抑制 | Mermet-Joret, N. | N/A | Dual-color optical activation and suppression of neurons with high temporal precision | |
| 神经调节器通过在超通道中转移活动流，在递归神经网络中生成多种与上下文相关的行为。 | Tsuda, B. | N/A | Neuromodulators generate multiple context-relevant behaviors in a recurrent neural network by shifting activity flows in hyperchannels | |
| CHAS是一种反卷积工具，用于推断神经和精神疾病的大脑组蛋白乙酰化研究中的细胞类型特异性特征。 | Murphy, K. B. | N/A | CHAS, a deconvolution tool, infers cell type-specific signatures in bulk brain histone acetylation studies of neurological and psychiatric disorders | |
| 健康年轻成人步态控制中认知参与的运动学和神经肌肉特征 | LANA, V. | N/A | Kinematic and neuromuscular characterization of cognitive involvement in gait control in healthy young adults | |
| 骨骼肌和神经肌肉执行器的Hill型模型：系统性综述 | Caillet, A. H. | N/A | Hill-type models of skeletal muscle and neuromuscular actuators: a systematic review | |
| 心形蚌壳通过捆绑的光纤电缆和聚光透镜将阳光传递给共生藻类。 | McCoy, D. E. | N/A | Heart cockle shells transmit sunlight to photosymbiotic algae using bundled fiber optic cables and condensing lenses | |
| PACESS：基于AI的大规模三维骨髓组织图像细胞提取与空间统计 | Adams, G. | N/A | PACESS: Practical AI-based Cell Extraction and Spatial Statistics for large 3D bone marrow tissue images | |
| 使用针电极阵列对糖尿病小纤维周围神经病变进行经皮电生理记录：小鼠和人类的实验研究 | Blaszkiewicz, M. | N/A | Transdermal Electrophysiological Recordings of Diabetic Small Fiber Peripheral Neuropathy Using a Needle Electrode Array in Mice and Men | |
| 小ARF样2 GTP酶TITAN 5与铁调节转运蛋白1的动态调控相关 | Mohr, I. | N/A | Small ARF-like 2 GTPase TITAN 5 is linked with the dynamic regulation of IRON-REGULATED TRANSPORTER 1 | |
| zol & fai：大规模目标基因簇的检测与进化研究 | Salamzade, R. | N/A | zol & fai: large-scale targeted detection and evolutionary investigation of gene clusters | |
| 用于研究果蝇联想学习的驱动线 | Shuai, Y. | N/A | Driver lines for studying associative learning in Drosophila | |
| SARS-CoV-2刺突抗体与登革病毒发生交叉反应，并在体外和体内增强感染 | Jakhar, K. | N/A | SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection in-vitro and in-vivo | |
| JointPRS：一种数据自适应框架，用于整合遗传相关性的多群体遗传风险预测 | Xu, L. | N/A | JointPRS: A Data-Adaptive Framework for Multi-Population Genetic Risk Prediction Incorporating Genetic Correlation | |
| 使用基于聚类的排列检验来估计MEG/EEG起始时间：问题有多严重？ | Rousselet, G. A. | N/A | Using cluster-based permutation tests to estimate MEG/EEG onsets: how bad is it? | |
| TIPE通过促进PKM2/HIF-1α轴的糖酵解作用，在黑色素瘤中驱动类似癌症干细胞的表型。 | Tian, M. | N/A | TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1alpha axis in melanoma | |
| 流感聚合酶活性位点的高分辨率结构揭示了复制起始类似构型中保守的双碱性基序在PA亚基中的关键作用 | Cusack, S. | N/A | High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit | |
| 人类肌肉中大量运动单位的识别揭示了神经调质输入对速率编码的多样影响 | Avrillon, S. | N/A | The identification of extensive samples of motor units in human muscles reveals diverse effects of neuromodulatory inputs on the rate coding | |
| 在单细胞分辨率下通过基因信号模式分析绘制基因空间图谱 | Venkat, A. | N/A | Mapping the gene space at single-cell resolution with gene signal pattern analysis | |
| 在衰老过程中，人类细胞的着丝粒失活是可以被挽救的。 | Sikder, S. | N/A | Centromere inactivation during aging can be rescued in human cells | |
| 肠道与鼻咽微生物群组成之间的关系可以预测COVID-19的严重程度。 | Martin-Castano, B. | N/A | The relationship between gut and nasopharyngeal microbiome composition can predict the severity of COVID-19 | |
| Caspase-2通过杀死具有多余中心体的细胞来发挥作用。 | Rizzotto, D. | N/A | Caspase-2 kills cells with extra centrosomes | |
| 多功能聚合结构域决定了拟南芥中表观遗传沉默的开始 | Schulten, A. | N/A | Multifunctional polymerization domains determine the onset of epigenetic silencing in Arabidopsis | |
| 体积电子显微镜揭示了人死后前额叶皮层的3D突触纳米结构 | Glausier, J. R. | N/A | Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex | |
| 沙门氏菌利用植物免疫系统产生的活性氧物种来增强其定殖能力。 | Tzpilevich, E. | N/A | Salmonella exploits the reactive oxygen species generated by the plant immune system to enhance colonization | |
| 不确定性的多重及特定主题角色在奖励导向决策中的作用 | Paunov, A. | N/A | Multiple and subject-specific roles of uncertainty in reward-guided decision-making | |
| 通过计算允许先前有问题的序列参数的第二种对比度，对基于MP2RAGE的R1映射中的B1+不均匀性容差进行3T研究 | Ruijters, L. | N/A | A 3T investigation of B1+-inhomogeneity tolerance in MP2RAGE-based R1-mapping by calculating second contrast that permits previously problematic sequence parameters | |
| 寒冷诱导脑区选择性细胞活动依赖性脂质代谢 | Min, H. | N/A | Cold induces brain region-selective cell activity-dependent lipid metabolism | |
| 最快和最密集反应的协调体现了老鼠类似人类的反应时间。 | Kim, C. H. | N/A | Harmonization of the fastest and densest responses embodies the humanlike reaction time of mice | |
| 细菌应激颗粒通过排除核糖核酸酶来保护mRNA | Pei, L. | N/A | Bacterial stress granule protects mRNA through ribonucleases exclusion | |
| 前额叶和颞叶区域的双向连接变化反映了多声部音乐中的图形-背景反转 | Kim, C. H. | N/A | Bidirectional connectivity changes in the frontotemporal areas reflect figure-ground reversal in multivoiced music | |
| 未预料到的共价抑制剂和合成配体与PPARγ的共结合机制 | Shang, J. | N/A | Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARgamma | |
| 实验性创伤性脑损伤后海马θ-γ耦合和锋电位场相干性的破坏 | Adam, C. D. | N/A | Disrupted Hippocampal Theta-Gamma Coupling and Spike-Field Coherence Following Experimental Traumatic Brain Injury | |
| 无脊椎动物中Cdk4/6-Cdkn2系统的演化 | Yuki, S. | N/A | Evolution of the Cdk4/6-Cdkn2 system in invertebrates | |
| 昼夜节律调节血流对基于纳米颗粒的靶向药物递送在虚拟体内动脉几何结构中的影响 | Goraya, S. A. | N/A | Effect of Circadian Rhythm Modulated Blood Flow on Nanoparticle based Targeted Drug Delivery in Virtual In Vivo Arterial Geometries | |
| 一个转录因子五重奏调控水稻鞘鞘表达 | Hua, L. | N/A | A transcription factor quintet orchestrating bundle sheath expression in rice | |
| 人类下丘中的快速且刺激特异性的异常检测 | Wetekam, J. | N/A | Rapid and Stimulus-Specific Deviance Detection in the Human Inferior Colliculus | |
| regulaTER：一个用于研究转座元件调控作用的R语言库。 | Eskier, D. | N/A | regulaTER: An R Library to Study the Regulatory Roles of Transposable Elements. | |
| 一种能够穿越血脑屏障的肽-神经降压素偶联物，在小鼠癫痫持续状态后诱导了与抗惊厥、神经保护和抗炎特性相关的药理性体温过低。 | Ferhat, L. | N/A | A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice | |
| 内在无序蛋白质凝聚体中动力学的异质性减缓 | Mukherjee, S. | N/A | Heterogeneous Slowdown of Dynamics in the Condensate of an Intrinsically Disordered Protein | |
| BioLP-bench：评估大型语言模型对生物实验室协议的理解能力 | Ivanov, I. | N/A | BioLP-bench: Measuring understanding of biological lab protocols by large language models | |
| 在烟草中异源生产环肽素B：揭示植物特异性插入结构域在蛋白质功能和亚细胞定位中的作用 | Muthusamy, S. | N/A | Heterologous Production of Cyprosin B in Nicotiana benthamiana: Unveiling the Role of the Plant-Specific Insert Domain in Protein Function and Subcellular Localization | |
| 遗传抑制相互作用在不同遗传背景下高度保守 | Paltenghi, C. | N/A | Genetic suppression interactions are highly conserved across genetic backgrounds | |
| 柱状胆碱能神经传递到果蝇T5细胞 | Samara, E. | N/A | Columnar cholinergic neurotransmission onto T5 cells of Drosophila | |
| 两种形态迥异的蜂媒授粉茄科植物花朵中花粉的命运 | Vasquez-Castro, C. A. | N/A | The fate of pollen in two morphologically contrasting buzz-pollinated Solanum flowers | |
| 磷酸酶非依赖性抑制黏膜炎症和疾病进展的沙门氏菌SopB | Diab, N. | N/A | Phosphatase-independent suppression of mucosal inflammation and disease progression by Salmonella SopB | |
| 内皮CD45在调节动脉粥样硬化中的内皮间质转化的新作用 | Peng, Q. | N/A | Novel Role of Endothelial CD45 in Regulating Endothelial-to-Mesenchymal Transition in Atherosclerosis | |
| 海马体中奖励的预测编码 | Yaghoubi, M. H. | N/A | Predictive Coding of Reward in the Hippocampus | |
| 丝虫精子发生过程中重组、X染色体失活及着丝粒蛋白的动态变化 | Toubiana, W. | N/A | Dynamics of recombination, X inactivation and centromere proteins during stick insect spermatogenesis | |
| 增加留尼汪岛节肢动物名录 | Nibouche, S. | N/A | Additions to the list of arthropods of Reunion Island | |
| 质子结合的变构调节赋予囊泡谷氨酸转运蛋白氯离子活化和谷氨酸选择性 | Borghans, B. | N/A | Allosteric modulation of proton binding confers Cl- activation and glutamate selectivity to vesicular glutamate transporters | |
| 转录因子Traffic jam在果蝇卵巢中调控体细胞piRNA通路 | Alizada, A. | N/A | The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries | |
| 急性饮食甲硫氨酸限制突显了新皮质发育对代谢变化的敏感性 | Saha, S. | N/A | Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations | |
| 裂变酵母SUMO靶向泛素连接酶Slx8在功能上与核周的成簇着丝粒和沉默的交配型区域相关联。 | Chakraborty, S. | N/A | The fission yeast SUMO-targeted Ubiquitin Ligase Slx8 functionally associates with clustered centromeres and the silent mating type region at the nuclear periphery | |
| 在磷酸盐限制条件下，革兰氏阴性ESKAPE病原体通过替代脂质合成途径促进抗生素耐受性。 | Olea-Ozuna, R. J. | N/A | Alternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens | |
| IgSF蛋白DIP-α和Dpr10的关键亲和窗口对于适当的运动神经元树突化是必需的。 | Lopez, D. | N/A | A critical affinity window for IgSF proteins DIP-alpha and Dpr10 is required for proper motor neuron arborization | |
| 河流丽鱼（辐鳍鱼纲，慈鲷科）的完整线粒体基因组，重点关注盲丽鱼L. lethops | Jimenez, S. | N/A | Complete mitochondrial genomes of riverine Lamprologus (Actinopterygii, Cichlidae) with an emphasis on the blind cichlid L. lethops | |
| 适应性唤醒调节：通过儿茶酚胺增强唤醒来药理学地改变耶克斯-多德森曲线的峰值 | Beerendonk, L. | N/A | Adaptive arousal regulation: Pharmacologically shifting the peak of the Yerkes-Dodson curve by catecholaminergic enhancement of arousal | |
| ABHD11介导的去甘露糖化作用调控TCA循环和T细胞代谢 | Grice, G. L. | N/A | ABHD11 mediated deglutarylation regulates the TCA cycle and T cell metabolism | |
| 母体致肥胖饮食在中孕期会破坏子宫内膜的免疫和血管稳态，但不会影响螺旋动脉的重塑。 | Bellissimo, C. J. | N/A | Maternal obesogenic diet disrupts mid-gestation decidual immune and vascular homeostasis without impairing spiral artery remodelling | |
| 遗传性铜缺乏和儿童神经退行性变模型中的适应性蛋白质合成 | Lane, A. R. | N/A | Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration | |
| 蛋白质稳态和代谢功能障碍在特定的一组储存诱导的衰老红细胞中，这些红细胞被靶向清除 | Peltier, S. | N/A | Proteostasis and metabolic dysfunction in a distinct subset of storage-induced senescent erythrocytes targeted for clearance | |
| 人类动脉粥样硬化斑块的综合单细胞图谱 | Traeuble, K. | N/A | Integrated single-cell atlas of human atherosclerotic plaques | |
| 甲型流感病毒利用宿主细胞中膜细胞骨架肌动蛋白丝的运动性进行其基因组的包装。 | Wang, I.-H. | N/A | Influenza A virus exploits the motility of membrane cytoskeletal actomyosin filaments for its genome packaging in the host cell | |
| 胞内体重组疗法：一种从囊性纤维化中进行的生物学拯救 | Cho, W. J. | N/A | Porosome reconstitution therapy: A biologic rescue from cystic fibrosis | |
| 自闭症和智力障碍相关MYT1L基因突变影响人类皮层中间神经元的分化、成熟和生理功能 | Prakasam, R. | N/A | Autism and Intellectual Disability-Associated MYT1L Mutation Alters Human Cortical Interneuron Differentiation, Maturation, and Physiology | |
| 吉尔伽美什，果蝇酪蛋白激酶1g，对于肌球蛋白依赖的连接增强和上皮折叠是必需的。 | Gu, L. | N/A | gilgamesh, Drosophila casein kinase 1g, is required for myosin-dependent junction strengthening and epithelial folding | |
| 心脏成纤维细胞通过胶原蛋白信号通路调节心肌和冠状血管的发育。 | Deng, Y. | N/A | Cardiac Fibroblasts regulate myocardium and coronary vasculature development via the collagen signaling pathway | |
| 大规模小鼠突变分析鉴定出影响脊椎发育的新基因。 | Ibarra-Soria, X. | N/A | Large-scale mouse mutagenesis identifies novel genes affecting vertebral development. | |
| 卵母细胞锌转运蛋白Slc39a10/Zip10是小鼠受精过程中锌火花调节器。 | Kageyama, A. | N/A | The oocyte zinc transporter Slc39a10/Zip10 is a regulator of zinc sparks during fertilization in mice. | |
| 弓形虫感染会误导胎盘滋养层细胞谱系的分化 | Cabo, L. F. | N/A | Toxoplasma gondii infection misdirects placental trophoblast lineage specification | |
| 长期活体成像、细胞鉴定及再生甲壳动物腿中的细胞追踪 | Cevrim, C. | N/A | Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs | |
| 电泳相关离子迁移技术在毛细管电泳质谱单细胞蛋白质组学中的应用 | Shen, B. | N/A | Electrophoresis-Correlative Ion Mobility Deepens Single-cell Proteomics in Capillary Electrophoresis Mass Spectrometry | |
| Notch活性的基本和双重作用对自然转分化事件的影响 | Daniele, T. | N/A | Essential and dual effects of Notch activity on a natural transdifferentiation event | |
| 深度学习在荧光全内反射显微镜中动态胞吐事件的检测 | Lachuer, H. | N/A | Deep learning detection of dynamic exocytosis events in fluorescence TIRF microscopy | |
| 硫胺素预处理控制马铃薯早疫病：其有效性及分子机制的研究 | Berrian, T. W. | N/A | Thiamin priming to control early blight in potato: investigation of its effectiveness and molecular mechanisms | |
| 细胞松弛素B对肌动蛋白结合蛋白功能的急性干扰 | Lambert, C. | N/A | Differential interference with actin-binding protein function by acute Cytochalasin B | |
| 蜕膜自然杀伤细胞促进绒毛外滋养层发育途径：来自滋养层类器官共培养的证据 | Zych, M. | N/A | Decidual natural killer cells promote extravillous trophoblast developmental pathways: evidence from trophoblast organoid co-cultures | |
| 秀丽隐杆线虫染色体内重组率的菌株间变异 | Matharage, D. U. | N/A | Inter-strain variation in intra-chromosomal rates of recombination in Caenorhabditis elegans | |
| 果蝇饮食限制介导的寿命结果中的随机性 | Mosley, O. L. | N/A | Stochasticity in dietary restriction-mediated lifespan outcomes in Drosophila | |
| ATG9小泡是一种细胞内纳米小泡的亚型。 | Fesenko, M. | N/A | ATG9 vesicles are a subtype of intracellular nanovesicle | |
| 母亲孕期抑郁症状与新生儿胼胝体完整性之间的关联及其与孕期头发皮质醇浓度的关系 | Mariani Wigley, I. L. C. | N/A | Association between maternal depressive symptoms and hair cortisol concentration during pregnancy with corpus callosum integrity in newborns | |
| 利用三倍频显微镜对生理上保存完好的人脑组织中的髓鞘病理进行动态成像 | Meijns, N. | N/A | Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy | |
| 在环境与遗传空间中的杂种优势 | Sandstedt, G. D. | N/A | Heterosis across an environmental and genetic space | |
| 突触小泡停靠与融合孔调节：神经钙传感器Synaptotagmin-1的作用 | Tsemperouli, M. | N/A | Vesicle docking and fusion pore modulation by the neuronal calcium sensor Synaptotagmin-1 | |
| 水滴的燃烧玻璃效应在拟南芥叶片叶绿体基质中触发了内质网衍生的钙响应 | Kuang, D. | N/A | Burning glass effect of water droplets triggers an ER-derived calcium response in the chloroplast stroma of Arabidopsis thaliana leaves | |
| 通过时间和波长分辨的氧化还原生物传感器以及叶绿素荧光量化电子传递相关的氧化信号 | Hipsch, M. | N/A | Quantification of electron transport-related oxidative signals by time and wavelength-resolved redox biosensors and chlorophyll fluorescence | |
| 探索玉米地方品种根系表型的产量稳定性和适应性景观的计算机模拟 | Lopez-Valdivia, I. | N/A | Exploring yield stability and the fitness landscape of maize landrace root phenotypes in silico | |
| 不同的输入特异性机制使得突触前稳态可塑性成为可能 | Chien, C. | N/A | Distinct input-specific mechanisms enable presynaptic homeostatic plasticity | |
| ERK2二聚体在突触可塑性和记忆中的作用 | Ojea Ramos, S. | N/A | Role of ERK2 dimerization in synaptic plasticity and memory | |
| 辅助调节通过NLRP3/IL-1途径塑造适应性免疫反应，并促进训练性免疫耐受。 | Boccia, T. | N/A | Adjuvant conditioning shapes the adaptive immune response and promotes trained immunotolerance via NLRP3/IL-1 | |
| 雷帕霉素改变了雌性果蝇对氨基酸和糖的摄食偏好 | Yu, G. | N/A | Rapamycin alters the feeding preference for amino acids and sugar in female Drosophila | |
| 突触间可塑性变异性的平衡，以生成输入端广泛的递质释放恒定性。 | Aghi, K. | N/A | Synapse-to-synapse plasticity variability balanced to generate input-wide constancy of transmitter release | |
| 小鼠中自发再生的皮质脊髓神经元 | Fait, B. W. | N/A | Spontaneously regenerative corticospinal neurons in mice | |
| 辅助嗅球中的突触抑制调节信息素定位学习和记忆 | Marathe, S. D. | N/A | Synaptic inhibition in the accessory olfactory bulb regulates pheromone location learning and memory | |
| 利用突触囊泡释放和再循环机制进行分子递送至神经元 | Yee, K. K. | N/A | Harnessing Synaptic Vesicle Release and Recycling Mechanism for Molecule Delivery to Neurons | |
| 极端疼痛毒液的多重作用机制 | Borjon, L. J. | N/A | Multiple mechanisms of action of an extremely painful venom | |
| 神经肽能对胆碱能传递的调控丧失会引发肌肉细胞中由CaV1介导的稳态补偿 | Shao, J. | N/A | Loss of neuropeptidergic regulation of cholinergic transmission induces CaV1-mediated homeostatic compensation in muscle cells | |
| 整合双目视觉和运动状态以促进猎物追捕 | Tian, G. | N/A | Integration of binocular vision and motor state to promote prey pursuit | |
| m6A RNA修饰在转录组学层面调节了衰老和突触核蛋白病小鼠模型中的突触功能。 | Chopra, A. | N/A | The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy | |
| 使用冷冻电镜和人工智能进行蛋白质鉴定指导了改进的样品纯化 | Carr, K. D. | N/A | Protein identification using cryo-EM and artificial intelligence guides improved sample purification | |
| 外纹状皮质中误报的神经动力学基础 | Sahoo, B. | N/A | Neural Dynamics Underlying False Alarms in Extrastriate Cortex | |
| Context-Seq: 基于CRISPR-Cas9靶向纳米孔测序的抗菌药物耐药性传播动力学研究 | Fuhrmeister, E. R. | N/A | Context-Seq: CRISPR-Cas9 Targeted Nanopore Sequencing for Transmission Dynamics of Antimicrobial Resistance | |
| 解锁隐藏噬菌体多样性，以完成BASEL收藏，系统探索噬菌体-宿主相互作用 | Humolli, D. | N/A | Unlocking hidden phage diversity to complete the BASEL collection for systematic exploration of phage-host interactions | |
| 一种古菌的CBASS系统能在不杀死宿主细胞的情况下消除病毒 | Choudhary, D. K. | N/A | An archaeal CBASS system eliminates viruses without killing the host cells | |
| 西高加索蝙蝠病毒在意外宿主体内的免疫学发现 | Castellan, M. | N/A | Immunological findings of West Caucasian bat virus in an accidental host | |
| 评估TRX和DUF148抗原用于检测犬类潜伏期麦地那龙线虫（Dracunculus medinensis）感染的性能 | Hakimi, H. | N/A | Assessing the performance of TRX and DUF148 antigens for detection of prepatent Guinea worm (Dracunculus medinensis) infection in dogs | |
| 计算研究表明揭示了条形柄锈菌小麦专化型效应蛋白的结构特征和新家族 | Asghar, R. | N/A | Computational studies reveal structural characterization and novel families of Puccinia striiformis f. sp. tritici effectors | |
| 通过凝集素微阵列对乳酸乳球菌乳酸亚种突变体进行糖型分析 | Suzuki, E. | N/A | Glyco-phenotyping of mutants of Lacticaseibacillus paracasei by lectin microarray | |
| 对单个噬菌体和噬菌体混合物的宏基因组分析显示，存在温和噬菌体和细菌DNA的污染情况。 | Peng, X. | N/A | Metagenomic analyses of single phages and phage cocktails show instances of contamination with temperate phages and bacterial DNA | |
| 不同寡聚态流感病毒核蛋白的多克隆和单克隆抗体分析 | Myers, M. L. | N/A | Analysis of polyclonal and monoclonal antibody to the influenza virus nucleoprotein in different oligomeric states | |
| ves1α基因表达是巴贝斯虫感染的红细胞与内皮细胞粘附的主要决定因素。 | Hakimi, H. | N/A | ves1α genes expression is the major determinant of Babesia bovis-infected erythrocytes cytoadhesion to endothelial cells | |
| 一种基于黄素的新型革兰氏阳性菌Microbacterium deferre sp. nov.菌株A1-JK中的胞外电子传递策略，该菌株从电缆细菌富集物中分离得到。 | Lustermans, J. J. M. | N/A | A flavin-based extracellular electron transfer strategy in a novel gram-positive microbe Microbacterium deferre sp. nov. strain A1-JK, isolated from cable bacteria enrichments | |
| 电磁波能破坏SARS-CoV-2的刺突蛋白，并降低SARS-CoV-2病毒样颗粒（SC2-VLP）的感染性。 | Granatir, S. | N/A | Electromagnetic waves destabilize the SARS-CoV-2 Spike protein and reduce SARS-CoV-2 Virus-Like Particle (SC2-VLP) infectivity | |
| 通过筛选组蛋白突变体，我们发现组蛋白H3的N端尾部内存在一个区域，该区域调控Cyc8在活性FLO1位点上独立于Tup1的抑制作用。 | Singh, R. | N/A | Screening of histone mutants reveals a domain within the N-terminal tail of histone H3 that regulates the Tup1-independent repressive role of Cyc8 at the active FLO1 | |
| 通过调节炎症和促消退脂质介质的平衡，改善体积性肌肉损失损伤的功能性肌肉再生 | Turner, T. C. | N/A | Improving Functional Muscle Regeneration in Volumetric Muscle Loss Injuries by Shifting the Balance of Inflammatory and Pro-Resolving Lipid Mediators | |
| NucBalancer：优化样本混合用于测序的条码序列选择流程 | Gupta, S. | N/A | NucBalancer: Streamlining Barcode Sequence Selection for Optimal Sample Pooling for Sequencing | |
| 应激介导的生长决定大肠杆菌分裂位点的形态发生 | Pelech, P. | N/A | Stress-mediated growth determines E. coli division site morphogenesis | |
| 凝血因子XII参与了肾素激活、心力衰竭进展及死亡率的相关过程。 | Gladysheva, I. P. | N/A | Coagulation factor XII contributes to renin activation, heart failure progression, and mortality | |
| 一种KCa 2.2/2.3开放剂可逆转ET-1诱导的高血压小鼠NLRP3的激活 | Sobrano Fais, R. | N/A | A KCa 2.2/2.3 opener reverses ET-1 induced NLRP3 activation in hypertensive mice | |
| 细菌的储层计算 | Faulon, J.-L. | N/A | Reservoir Computing with Bacteria | |
| 血清素能致幻剂DOI会损害听觉皮层的异常检测能力。 | Horrocks, M. | N/A | The serotonergic psychedelic DOI impairs deviance detection in the auditory cortex | |
| 不依赖宿主蛋白酶的寨卡病毒感染性成熟颗粒的生物发生 | Dowd, K. A. | N/A | pr-independent biogenesis of infectious mature Zika virus particles | |
| 综合宿主体内感染动力学揭示了被忽视的媒介物种白纹伊蚊（Aedes scutellaris）具有较高的虫媒病毒传播潜力 | Samung, Y. | N/A | Comprehensive intra-host infection kinetics reveals high arbo-flavivirus transmission potential by neglected vector species, Aedes scutellaris | |
| 双天线N-聚糖作为MARTX毒素在弧菌致病性中的受体 | Chen, J. | N/A | Biantennary N-glycans As Receptors for MARTX Toxins in Vibrio Pathogenesis | |
| 卡尔斯巴德洞窟国家公园的洞穴池中存在着多样化的噬菌体群落和新型病毒序列。 | Ulbrich, J. | N/A | Cave pools in Carlsbad Caverns National Park contain diverse bacteriophage communities and novel viral sequences | |
| 无机多磷酸盐与严紧反应共同调控大肠杆菌的细胞分裂和细胞形态 | Hamm, C. W. | N/A | Inorganic polyphosphate and the stringent response coordinately control cell division and cell morphology in Escherichia coli | |
| 衣原体效应蛋白Tarp的N端与宿主Hippo通路相互作用。 | Aranjuez, G. F. | N/A | The N-terminus of the Chlamydia trachomatis effector Tarp engages the host Hippo pathway | |
| MtvS调节弗朗西氏菌V-A型CRISPR-Cas系统 | Brodmann, M. | N/A | MtvS Regulates the Francisella Type V-A CRISPR-Cas System | |
| Hox转录因子Ultrabithorax的协同DNA和RNA结合能力协调剪接并塑造体内同源异型功能 | Blanco, C. | N/A | Synergistic DNA and RNA binding of the Hox transcription factor Ultrabithorax coordinates splicing and shapes in vivo homeotic functions | |
| Cas9核酸酶的策略性靶向扩展了串联基因阵列 | Takesue, H. | N/A | Strategic targeting of Cas9 nickase expands tandem gene arrays | |
| 营养缺乏会激活与炎症性肠病风险相关的细胞外基质重塑基因增强子，这一过程在成纤维细胞中尤为显著。 | Secchia, S. | N/A | Nutrient starvation activates ECM remodeling gene enhancers associated with inflammatory bowel disease risk in fibroblasts | |
| 由III组代谢型谷氨酸受体介导的抑制作用调节着缰核的活动及防御行为 | Ostenrath, A. M. | N/A | Inhibition mediated by group III mGluRs regulates habenula activity and defensive behaviors | |
| 稳定选择使复杂性状的尾部富集了具有较大效应的罕见等位基因。 | Ori, A. P. | N/A | Stabilising selection enriches the tails of complex traits with rare alleles of large effect | |
| 老年人大脑中微小RNA的基因调控及其对神经精神疾病的影响 | Vattathil, S. M. | N/A | Genetic regulation of microRNAs in the older adult brain and their contribution to neuropsychiatric conditions | |
| 利用批量和靶向单细胞激活技术对基因组调控景观进行敏感解剖 | Vucicevic, D. | N/A | Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation | |
| GAF结构域介导肌醇焦磷酸底物在PPIP5K磷酸酶中的通道作用 | Raia, P. | N/A | A GAF domain mediates inositol pyrophosphate substrate channeling in PPIP5K phosphatases | |
| 二聚体SMC复合物进行的环挤压对称性依赖于DNA张力 | Pradhan, B. | N/A | Symmetry of loop extrusion by dimeric SMC complexes is DNA-tension-dependent | |
| ARF降解定义了生长素反应中一个高度保守的步骤。 | de Roij, M. | N/A | ARF degradation defines a deeply conserved step in auxin response | |
| 单锥光感受器通过注视转移来体验全局图像统计信息。 | Morimoto, T. | N/A | Single cone photoreceptors experience global image statistics through gaze shifts | |
| α5-GABAA受体的正向变构调节可预防PS19小鼠模型中神经元萎缩和认知功能下降，且独立于tau缠结的积累。 | Dharavath, R. N. | N/A | Positive Allosteric Modulation of the α5-GABAA receptors prevents neuronal atrophy and cognitive decline independently of tau tangle accumulation in the PS19 mouse model | |
| 在额下皮质中，解剖学上不同的区域受到任务和阅读技能的调节。 | Stone, H. L. | N/A | Anatomically distinct regions in the inferior frontal cortex are modulated by task and reading skill | |
| 肾上腺素能C1神经元通过投射到中脑导水管周围灰质（PAG）来增强焦虑。 | Fernandez-Pena, C. | N/A | Adrenergic C1 neurons enhance anxiety via projections to PAG | |
| 辅助剂对疫苗诱导的体液免疫反应和保护作用的影响：在鼻腔和生殖道定植病原性奈瑟菌的临床前模型中 | Islam, E. A. | N/A | Adjuvant-dependent impacts on vaccine-induced humoral responses and protection in preclinical models of nasal and genital colonization by pathogenic Neisseria | |
| 体外构建巨噬细胞极化模型：以Raw 264.7巨噬细胞系为例 | Yee, K. K. | N/A | An in vitro modelling of resolving macrophage with Raw 264.7 macrophage cell line | |
| 小鼠心脏中伴侣复合体的年龄相关变化 | Bhat, P. D. | N/A | Age-dependent Changes in a Chaperone Complex in the Mouse Heart | |
| 全球蛋白质组学揭示了电离辐射诱导的亚细胞特异性抗铁死亡反应 | Christopher, J. A. | N/A | Global proteomics indicates subcellular-specific anti-ferroptotic responses to ionizing radiation | |
| 有丝分裂驱动蛋白-5是轴突生长的动态刹车 | Lu, W. | N/A | 'Mitotic' kinesin-5 is a dynamic brake for axonal growth | |
| 钙网蛋白在蝴蝶翅膀鳞片细胞内的角质层沉积和横梁形成过程中是必需的。 | Hong, R. | N/A | Calreticulin is required for cuticle deposition and trabeculae formation inside butterfly wing scale cells | |
| PSMA特异性CAR改造的巨噬细胞用于前列腺癌治疗 | Xu, Y. | N/A | PSMA-specific CAR-engineered macrophages for therapy of prostate cancer | |
| 肌球蛋白簇动力学决定上皮伤口环收缩 | Bhat, A. | N/A | Myosin cluster dynamics determines epithelial wound ring constriction | |
| 无参数清晰图像反卷积（CLID）技术用于单帧活细胞超分辨率成像 | Xue, F. | N/A | Parameter-free clear image deconvolution (CLID) technique for single-frame live-cell super-resolution imaging | |
| 痛风药物抑制尿酸转运蛋白URAT1的分子基础 | Suo, Y. | N/A | Molecular basis of the urate transporter URAT1 inhibition by gout drugs | |
| # BioRxiv 2024-09-11 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 紫色叶背植物：气孔分布指标的资源库。 | Almeida Filho, H. A. | N/A | Plants with purple abaxial leaves: A repository of metrics from stomata distribution. | |
| 来自PRPF31+/- hiPSC-RPE的细胞外囊泡中的RNA含量显示出作为视网膜变性生物标志物的潜力 | Getachew, H. | N/A | The RNA Content of Extracellular Vesicles from PRPF31+/- hiPSC-RPE Show Potential as Biomarkers of Retinal Degeneration | |
| 隔离和种间相互作用在产生岛屿哺乳动物辐射的功能多样性中的作用 | Nations, J. A. | N/A | The roles of isolation and interspecific interaction in generating the functional diversity of an insular mammal radiation | |
| 骨骼肌和神经肌肉执行器的Hill型模型：系统性综述 | Caillet, A. H. | N/A | Hill-type models of skeletal muscle and neuromuscular actuators: a systematic review | |
| 基于抑制的视网膜神经节细胞模型：跨物种和刺激的比较与泛化 | Shahidi, N. | N/A | Filter-based models of suppression in retinal ganglion cells: comparison and generalization across species and stimuli | |
| 大脑中的视觉同质性计算能够解决基于属性的视觉任务。 | Jacob, G. | N/A | Visual homogeneity computations in the brain enablesolving property-based visual tasks | |
| 重温扫视遗漏：扫视引发的模糊是什么样子的 | Schweitzer, R. | N/A | Saccadic omission revisited: What saccade-induced smear looks like | |
| 黄瓜（Cucumis sativus）激酶组：鉴定、注释及对白粉病感染的表达模式 | Costa, F. C. L. | N/A | The Cucumis sativus kinome: Identification, annotation, and expression patterns in response to powdery mildew infection | |
| 快速细胞内酸化是一种由褐飞虱对抗的新型植物防御反应。 | Jiang, Y. | N/A | Rapid intracellular acidification is a novel plant defense response countered by the brown planthopper | |
| 注意通过调整锐化来调节人类对物体的视觉反应 | Doostani, N. | N/A | Attention Modulates Human Visual Responses to Objects by Tuning Sharpening | |
| 改善焦虑研究：通过多状态总结测量的新方法揭示特质焦虑 | Varga, Z. K. | N/A | Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states | |
| 多拷贝基因系统中由遗传漂变驱动的极快进化的悖论 | Wang, X. | N/A | The paradox of extremely fast evolution driven by genetic drift in multi-copy gene systems | |
| M3NetFlow：一种用于综合多组学数据分析的新型多尺度多跳图AI模型 | Zhang, H. | N/A | M3NetFlow: A novel multi-scale multi-hop graph AI model for integrative multi-omic data analysis | |
| 新生成的成年神经元可保护小鼠免受癫痫的侵害。 | Jain, S. | N/A | Increasing adult-born neurons protects mice from epilepsy. | |
| 如果……会怎样？小脑皮层颗粒层的计算解剖学 | Gilbert, M. | N/A | What if...? Computational anatomy in the granular layer of the cerebellar cortex | |
| 铁剥夺吡咯啶对人类机会性病原体的抗菌活性 | Vollenweider, V. | N/A | Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens | |
| STING-CASM-GABARAP通路在溶酶体上激活LRRK2 | Bentley-DeSousa, A. | N/A | A STING-CASM-GABARAP Pathway Activates LRRK2 at Lysosomes | |
| 植物转录因子结合区域发现中的计算方法综合分析 | Jyoti, | N/A | Comprehensive analysis of computational approaches in plant transcription factors binding regions discovery | |
| 糖皮质激素时间药理学揭示了心肌细胞特异性GR-KLF15轴在心脏葡萄糖代谢中的新靶点 | El Abdellaoui-Soussi, F. | N/A | Glucocorticoid chrono-pharmacology unveils novel targets for the cardiomyocyte-specific GR-KLF15 axis in cardiac glucose metabolism | |
| PMP22通过其跨膜结构域与MPZ相关联，破坏这种相互作用会导致功能丧失表型，类似于与压力性麻痹易感性相关的遗传性神经病变（HNPP）。 | Pashkova, N. | N/A | PMP22 associates with MPZ via their transmembrane domains and disrupting this interaction causes a loss-of-function phenotype similar to hereditary neuropathy associated with liability to pressure palsies (HNPP). | |
| 蓝斑微胶质细胞在女性应激反应中的功能作用 | Smiley, C. E. | N/A | The functional role of locus coeruleus microglia in the female stress response | |
| 将梯度提升树应用于QTL定位，并结合Shapley加性解释 | Ishibashi, T. | N/A | Applying gradient tree boosting to QTL mapping with Shapley additive explanations | |
| NF1相关周围神经鞘瘤的综合基因组分析：更新后的生物样本库数据集 | Banerjee, J. | N/A | Integrated genomic analysis of NF1-associated peripheral nerve sheath tumors: an updated biorepository dataset | |
| 猴子外侧前额叶皮层的不同亚区对抽象序列及其组成部分有反应。 | Rodriguez, N. Y. | N/A | Different subregions of monkey lateral prefrontal cortex respond to abstract sequences and their components | |
| 苔藓动物中两侧对称动物基因组的融合、分裂与重组 | Lewin, T. D. | N/A | Fusion, fission, and scrambling of the bilaterian genome in Bryozoa | |
| DC1域蛋白Vacuoleless Gametophytes调控拟南芥雄蕊发育 | Amigo, N. L. | N/A | The DC1 domain protein Vacuoleless Gametophytes regulates stamen development in Arabidopsis | |
| 欧洲濒危睡鼠的单倍体型解析基因组与群体基因组学研究 | Byerly, P. | N/A | Haplotype-resolved genome and population genomics of the threatened garden dormouse in Europe | |
| Syngap1 调控小鼠听觉皮层中 Parvalbumin 阳性中间神经元的突触驱动和膜兴奋性。 | Francavilla, R. | N/A | Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex | |
| MIXL1在人诱导多能干细胞内胚层分化中的激活 | Osteil, P. | N/A | MIXL1 Activation in Endoderm Differentiation ofHuman Induced Pluripotent Stem Cells | |
| FLIGHTED：从噪声高吞吐量实验数据中推断适应性景观 | Sundar, V. | N/A | FLIGHTED: Inferring Fitness Landscapes from Noisy High-Throughput Experimental Data | |
| 噪声模式有助于在噪声中听清声音。 | Hicks, J. M. | N/A | Noise schemas aid hearing in noise | |
| 系统发育对从蛋白质序列数据推断功能区域的影响 | Dietler, N. | N/A | Impact of phylogeny on the inference of functional sectors from protein sequence data | |
| 模拟研究空间在药物敏感与耐药癌细胞相互作用中的作用 | Pugh, K. | N/A | Simulations probe the role of space in the interplay between drug-sensitive and drug-resistant cancer cells | |
| ChatNT：一种用于DNA、RNA和蛋白质任务的多模态对话代理 | Richard, G. | N/A | ChatNT: A Multimodal Conversational Agent for DNA, RNA and Protein Tasks | |
| 海洋深处的光波：对三种海笔（Pennatuloidea，Octocorallia，Anthozoa）发光系统的洞察 | Duchatelet, L. | N/A | Waves of light at the bottom of the ocean: insights into the luminous systems of three sea pens (Pennatuloidea, Octocorallia, Anthozoa) | |
| 基因组语言模型是否足够？探索基因组语言模型在蛋白质下游任务中的应用 | Boshar, S. | N/A | Are Genomic Language Models All You Need? Exploring Genomic Language Models on Protein Downstream Tasks | |
| SaprotHub：让蛋白质建模变得触手可及，惠及所有生物学家 | Su, J. | N/A | SaprotHub: Making Protein Modeling Accessible to All Biologists | |
| 幼鼠卵巢中的三波卵泡发育 | Yin, Q. | N/A | Three waves of ovarian follicles in juvenile mice | |
| BRCA1与非典型DNA结构的相互作用：对基因组维持和疾病机制的见解 | Lowran, K. | N/A | BRCA1 Interaction with Non-Canonical DNA Structures: Insights into Genome Maintenance and Disease Mechanisms | |
| ProTrek：通过三模态对比学习探索蛋白质宇宙 | Su, J. | N/A | ProTrek: Navigating the Protein Universe through Tri-Modal Contrastive Learning | |
| 组成性活化受体ADGRA3信号传导诱导脂肪组织产热 | Zhao, Z. | N/A | Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis | |
| 基于机器学习的多基因预测模型用于鼻咽癌辐射敏感性 | Li, K. | N/A | A multi-gene predictive model for the radiation sensitivity of nasopharyngeal carcinoma based on machine learning | |
| 一个调控水稻鞘细胞表达的转录因子五重奏 | Hua, L. | N/A | A transcription factor quintet orchestrating bundle sheath expression in rice | |
| 第三种情景记忆：情景熟悉度是一个与项目熟悉度和回忆不同的过程。 | Addante, R. J. | N/A | A third kind of episodic memory: Context familiarity is a distinct process from item familiarity and recollection | |
| 欧洲外生菌根担子菌纲真菌中宿主选择影响其孢子体积的估算 | Izumi, H. | N/A | Host selection in European ectomycorrhizal Basidiomycetes affects their estimated spore volumes | |
| 通过AI驱动的多参数理性设计增强Taq聚合酶的逆转录酶功能 | Tomilova, Y. E. | N/A | Enhancing the Reverse Transcriptase Function in Taq Polymerase via AI-driven Multiparametric Rational Design | |
| 基质硬度通过Piezo1介导的TTR活性调节神经元的成熟 | Kreysing, E. | N/A | Substrate stiffness regulates neuronal maturation via Piezo1-mediated TTR activity | |
| 强迫症中的认知序列受到前额叶皮层渐进活动的支持，并由症状严重程度介导。 | Doyle, H. | N/A | Cognitive sequences in obsessive-compulsive disorder are supported by frontal cortex ramping activity and mediated by symptom severity | |
| 质粒病毒维持使细菌种群从感染中恢复并实现病毒-细菌共存 | Sanchez-Martinez, R. | N/A | Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence | |
| CA3中的选择性抑制：通过异突触可塑性实现稳定模式完成的机制 | Kim, G. | N/A | Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity | |
| 敬畏在人类行为和大脑皮层中被描述为一种矛盾的体验：综合虚拟现实-脑电图研究 | Yi, J. | N/A | Awe is characterized as an ambivalent experience in the human behavior and cortex: integrated virtual reality-electroencephalogram study | |
| 发育调控的微外显子缺失对斑马鱼幼体大脑形态和功能的影响微乎其微 | Calhoun, C. C. S. | N/A | Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function | |
| 稻黄斑驳病毒的多模态传播：谷物、贸易与战争的历史与地理溯源 | Ndikumana, I. | N/A | Grains, trade and war in the multimodal transmission of Rice yellow mottle virus: an historical and phylogeographical retrospective | |
| 鞭毛滑动运动：一种新型的独立于推进的机制，用于沙门氏菌和大肠杆菌的表面迁移 | Panich, J. | N/A | Swashing motility: A novel propulsion-independent mechanism for surface migration in Salmonella and E. coli | |
| 编排不可能的化学反应：B12依赖型甲硫氨酸合成酶催化编排的结构快照 | Mendoza, J. | N/A | Orchestrating Improbable Chemistries: Structural Snapshots of B12-Dependent Methionine Synthase's Catalytic Choreography | |
| 通过尿素激活酶揭示构象动力学与底物结合之间的相互作用：一项单分子FRET研究 | Scheerer, D. | N/A | Enzyme activation by urea reveals the interplay between conformational dynamics and substrate binding:a single-molecule FRET study | |
| 肺炎支原体必需脂蛋白的结构表征 | Keles, I. | N/A | Structural characterization of an essential lipoprotein of Mycoplasma pneumoniae | |
| 在属Mus中TCRα和TCRβ位点的独特进化 | Peters, M. A. | N/A | Distinct evolution at TCRα and TCRβ loci in the genus Mus | |
| 哺乳动物大脑的体内光学透明化 | Talei Franzesi, G. | N/A | In Vivo Optical Clearing of Mammalian Brain | |
| 小说性Pannexin 1异构体在癌症中增加 | O'Donnell, B. L. | N/A | Novel Pannexin 1 isoform is increased in cancer | |
| 小鼠属中不同CD8+ α/β-TCR库的遗传决定因素 | Peters, M. A. | N/A | Genetic determinants of distinct CD8+ α/β-TCR repertoires in the genus Mus | |
| 在健康小鼠中使用Semaglutide给药改变了与压力和动机相关的行为 | Moreno, A. | N/A | Semaglutide Administration in Healthy Mice Alters Behaviour Related to Stress and Motivation | |
| 维多利亚州考拉中重组考拉逆转录病毒（recKoRV）的高频率检测表明KoRV的历史性整合 | Zheng, L. | N/A | A High Frequency of Detection of Recombinant Koala Retrovirus (recKoRV) in Victorian Koalas Suggests Historic Integration of KoRV | |
| 在狒狒群体中，早期哺乳期的同步性高预示着婴儿死亡率增加。 | Winans, J. C. | N/A | High early lactational synchrony within baboon groups predicts increased infant mortality | |
| 可扩展的从元细胞中识别谱系特异性基因调控网络的方法：NetID | Wang, W. | N/A | Scalable identification of lineage-specific gene regulatory networks from metacells with NetID | |
| 斑马鱼ebf3a突变体中感觉系统和大脑皮层的发育障碍 | Dang, N. D. P. | N/A | Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant | |
| 斑马鱼ebf3a突变体中感觉系统和大脑小脑的发育障碍 | Dang, N. D. P. | N/A | Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant | |
| 在啮齿动物前额叶皮层第2/3层的反复兴奋性突触中，短期易化现象的基础是易于释放的突触囊泡池的逐步充盈。 | Shin, J. | N/A | Progressive overfilling of readily releasable pool underlies short-term facilitation at recurrent excitatory synapses in layer 2/3 of the rat prefrontal cortex | |
| 遗漏响应神经元在听觉皮层中编码负预测误差和概率 | Yaron, A. | N/A | Omission-responsive neurons encode negative prediction error and probability in the auditory cortex | |
| 早期生活神经影像学：皮质区域划分在发育过程中的普遍性 | Tu, J. | N/A | Early Life Neuroimaging: The Generalizability of Cortical Area Parcellations Across Development | |
| 静默视觉言语中的眼球运动追踪未听到的声学信号，并与听觉经验相关联 | Benz, K. | N/A | Eye Movements in Silent Visual Speech track Unheard Acoustic Signals and Relate to Hearing Experience | |
| 基于外部奖励的技能学习对运动可塑性的影响 | Yadav, G. | N/A | Effects Of Extrinsic Reward Based Skill Learning On Motor Plasticity | |
| Shox2对于正常丘脑梭形波功能是必需的。 | Febbo, I. G. | N/A | Shox2 is necessary for normal thalamic spindle function | |
| 课程学习：任务复杂度的顺序获取增强了神经元的辨别能力 | Shujah, M. | N/A | Curriculum Learning: sequential acquisition of task complexity enhances neuronal discriminability | |
| 多表位免疫捕获亨廷顿蛋白揭示纹状体选择性分子特征 | Justice, J. L. | N/A | Multi-epitope immunocapture of huntingtin reveals striatum-selective molecular signatures | |
| 外侧缰核神经元的厌恶编码与行为状态调节 | Zouridis, I. S. | N/A | Aversion encoding and behavioral state modulation of lateral habenula neurons | |
| 通过扫视采样进行物体识别的时空证据积累 | Zheng, Z. | N/A | Spatiotemporal evidence accumulation through saccadic sampling for object recognition | |
| 调控因子的反相聚集塑造基因爆发 | Li, B. | N/A | Anti-phase clustering of regulatory factors shapes gene bursting | |
| 调控因子的反相聚集塑造了基因爆发 | Li, B. | N/A | Anti-phase clustering of regulatory factors shapes gene bursting | |
| 自然选择作用于复杂性状，阻碍了多基因评分在古代样本中的预测准确性。 | Anorve-Garibay, V. | N/A | Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples | |
| 高覆盖率、大规模并行单细胞基因组测序与CAP-seq技术 | Li, M. | N/A | High-coverage, massively parallel sequencing of single-cell genomes with CAP-seq | |
| 缺氧阻碍了颅神经嵴细胞向与颅面发育相关衍生物的分化 | Schmid, T. | N/A | Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development | |
| 多祖先全基因组关联研究揭示了与人类LINE-1和Alu拷贝数变异相关的位点 | Bravo, J. I. | N/A | Multi-ancestry GWAS reveals loci linked to human variation in LINE-1- and Alu-copy numbers | |
| EHZ2抑制增强了铂类化疗在侵袭性前列腺癌变异中的活性 | Latarani, M. | N/A | EHZ2 inhibition enhances the activity of platinum chemotherapy in aggressive variant prostate cancer | |
| 弥合灰质微观结构与功能连接组之间的差距：早产儿与足月婴儿的多模态磁共振成像研究 | Gondova, A. | N/A | Bridging the gap between grey-matter microstructural and functional connectomes: A multi-modal MRI study in preterm and full-term infants | |
| 通过视觉伽马振荡测量兴奋-抑制平衡的神经发育轨迹 | Rhodes, N. | N/A | Measuring the neurodevelopmental trajectory of excitatory-inhibitory balance via visual gamma oscillations | |
| 如果……？小脑微区中的计算解剖学，小脑网络的中层 | Gilbert, M. | N/A | What if...? Computational anatomy in the cerebellar microzone, the middle layer of the cerebellar network | |
| 裂解酵母SUMO靶向泛素连接酶Slx8在功能上与核周聚集的着丝粒以及沉默的交配型区域相关联。 | Chakraborty, S. | N/A | The fission yeast SUMO-targeted Ubiquitin Ligase Slx8 functionally associates with clustered centromeres and the silent mating type region at the nuclear periphery | |
| 学习空间转录组学中与表型相关的特征：PASSAGE方法 | Guo, C.-K. | N/A | Learning phenotype associated signature in spatial transcriptomics with PASSAGE | |
| 通过固定化白腐菌混合菌株酶解降解氯酚废水 | Liu, H. | N/A | Enzymatic Degrading Chlorophenol Wastewater by Mixed Strains of Immobilized White Rot Fungi | |
| 结蛋白突变在心肌成纤维细胞中通过beclin-1调节导致TGFβ1介导的病理性纤维化，这是结蛋白心肌病中的一个过程。 | Chen, H. V. | N/A | Desmoplakin mutations in cardiac fibroblasts cause TGF?1-mediated pathological fibrogenesis in desmoplakin cardiomyopathy via beclin-1 regulation | |
| 自然杂草种子捕食者能减少20%的谷物田中因杂草导致的作物产量损失。 | Muneret, L. | N/A | Natural weed seed predators reduce crop yield loss due to weeds by 20% in cereal fields | |
| 在7特斯拉下使用优化的点状编码时间减少与径向采集（PETRA）序列进行超短T2*成像，分别在标准和扩展回波时间下进行。 | Lockard, C. A. | N/A | Ultrashort-T2* mapping at 7 tesla using an optimized pointwise encoding time reduction with radial acquisition (PETRA) sequence at standard and extended echo times | |
| 胆管癌细胞系中的线粒体基因组改变 | Faipan, A. | N/A | Mitochondrial genomic alterations in cholangiocarcinoma cell lines | |
| Castleman病空间和单细胞图谱揭示关键基质细胞类型和细胞因子通路 | Smith, D. | N/A | Spatial and Single Cell Mapping of Castleman Disease Reveals Key Stromal Cell Types and Cytokine Pathways | |
| 烟酰胺核苷：通过上调烟酰胺磷酸核糖基转移酶介导的NAD水平，有望成为治疗心肌梗死诱导的急性肾损伤的有效疗法 | HABEICHI, N. J. | N/A | Nicotinamide riboside: A promising therapy for MI-induced acute kidney injury by upregulating nicotinamide phosphoribosyltransferase-mediated NAD levels | |
| 鼻内给予丹曲林纳米颗粒抑制脂多糖诱导的小鼠抑郁和焦虑行为 | Liu, J. | N/A | Intranasal dantrolene nanoparticles inhibit lipopolysaccharide-induced depression and anxiety behavior in mice | |
| 光系统II释放氧气后，能够进展到S1状态的S0状态的重整动力学 | Boussac, A. | N/A | Kinetics of reformation of an S0 state capable of progressing to an S1 state after the O2 release by Photosystem II | |
| 通过Pluronic辅助的同轴3D生物打印技术制备生物工程束状骨骼肌生物执行器 | Fuentes, J. | N/A | Bioengineering Fascicle-like Skeletal Muscle Bioactuators via Pluronic-Assisted Co-axial 3D Bioprinting | |
| 靶向CXCR4与-Pentixather联合使用显著提高小细胞肺癌患者的总体生存率 | Christensen, K. A. | N/A | Targeting CXCR4 with -Pentixather Significantly Increases Overall Survival in Small Cell Lung Cancer | |
| EyaHOST是一种模块化的遗传系统，用于研究果蝇（Drosophila melanogaster）中细胞间及肿瘤与宿主之间的相互作用。 | Teles-Reis, J. | N/A | EyaHOST a modular genetic system for investigation of intercellular and tumor-host interactions in Drosophila melanogaster | |
| 学习阅读将语音转换为语音图形表示：来自一项失匹配负波研究的证据 | Pattamadilok, C. | N/A | Learning to read transforms phonological into phonographic representations: Evidence from a Mismatch Negativity study | |
| 具身主体感代理的神经关联 | Regev Krugwasser, A. | N/A | Neural Correlates of the Embodied Sense of Agency | |
| 治疗期间癌症拦截：利用生长动力学创建一个连续变量以评估疾病反应 | Zhou, M. | N/A | Cancer Interception During Treatment: Using Growth Kinetics to Create a Continuous Variable for Assessing Disease Response | |
| KIF5A 调控轴突修复以及 SFPQ 颗粒和线粒体在人类运动神经元中的时间依赖性轴突运输 | Guerra San Juan, I. | N/A | KIF5A regulates axonal repair and time-dependent axonal transport of SFPQ granules and mitochondria in human motor neurons | |
| 瞬时大脑状态参与度的变化在个体发育过程中有所不同，并对执行功能的个体差异产生影响。 | Ye, J. | N/A | Variation in moment-to-moment brain state engagement changes across development and contributes to individual differences in executive function | |
| 通过工程化锌指抑制剂对SCN9A进行强效且特异性的抑制，用于治疗神经性疼痛 | samie, m. | N/A | Potent and selective repression of SCN9A by engineered zinc finger repressors for the treatment of neuropathic pain | |
| 早期NK细胞和T细胞功能障碍标志着肥胖和健康体重患者登革热病情的加重 | Gregorova, M. | N/A | Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight | |
| 在碳青霉烯酶的适应性进化过程中，上位效应推动了多个性状的快速分化。 | Dabos, L. | N/A | Epistasis drives rapid divergence across multiple traits during the adaptive evolution of a carbapenemase | |
| 通过宿主启动的专性外共生和代谢抑制实现早期真核生物起源 | Krishnan, N. | N/A | Early eukaryogenesis by host-initiated obligate ectosymbiosis and metabolic inhibition | |
| 癌症-免疫共进化由抗原突变积累所决定 | Wang, L. | N/A | Cancer-immune coevolution dictated by antigenic mutation accumulation | |
| 通过适应性实验揭示的真菌交配型染色体中的隐性负载 | Guyot, L. | N/A | Sheltered load in fungal mating-type chromosomes revealed by fitness experiments | |
| 微生物群驱动黄粉虫感染结果的性别二态性 | Seal, S. | N/A | Microbiota drives the sexually dimorphic infection outcomes in mealworm beetles | |
| EpipwR：针对连续结果的EWAS的高效功率分析 | Barth, J. P. | N/A | EpipwR: Efficient Power Analysis for EWAS withContinuous Outcomes | |
| 一种模拟人类妊娠期胎盘暴露于环境金属的生物工程模型 | Fattahi, P. | N/A | A bioengineered model of human placental exposure to environmental metals during pregnancy | |
| CryoTEN：利用Transformer高效增强冷冻电镜密度图 | Selvaraj, J. | N/A | CryoTEN: Efficiently Enhancing Cryo-EM DensityMaps Using Transformers | |
| 基于结构的计算分析：胰岛素受体与胰岛素抑制受体之间的相互作用 | Li, V. | N/A | Structure-Based Computational Analysis of Interactions between Insulin Receptor and Insulin Inhibitory Receptor | |
| 发现来自印度南部的一种新的地下鳗鲶新种 | RAMANATHAN, S. K. | N/A | Discovery of a new species of subterranean eel loach from southern India | |
| 味蕾中的死亡：死亡味觉细胞的形态特征及I型细胞的吞噬作用 | Wilson, C. E. | N/A | Death in the taste bud: Morphological features of dying taste cells and engulfment by Type I cells | |
| 神经递质对结构-功能耦合的贡献：来自灰质体积（GMV）和脑熵（BEN）的证据 | Song, D. | N/A | Neurotransmitters Contribute Structure-Function Coupling: Evidence from Grey Matter Volume (GMV) and Brain Entropy (BEN) | |
| 模拟CD8 T细胞衰竭：一种综合方法 | Manrique-Rincon, A. J. | N/A | Simulating CD8 T Cell Exhaustion: A Comprehensive Approach | |
| 关于前向采样方案密度的一个接近紧的下界 | Kille, B. | N/A | A near-tight lower bound on the density of forward sampling schemes | |
| 小鼠多巴胺能穹窿下区神经元的全脑投射 | Bono, B. S. | N/A | Brain-wide projections of mouse dopaminergic zona incerta neurons | |
| 单分子脂质生物传感器减轻内源效应蛋白的抑制作用 | Holmes, V. | N/A | Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins | |
| 优化扩展显微技术揭示了非洲爪蟾卵提取物中物种特异性的纺锤体微管组织 | Guilloux, G. | N/A | Optimized expansion microscopy reveals species-specific spindle microtubule organization in Xenopus egg extracts | |
| 蛋白质相互作用基序的全蛋白质组依赖性图谱 | Ambjoern, S. | N/A | A proteome-wide dependency map of protein interaction motifs | |
| 造血Tet2失活增强了免疫检查点阻断疗法的反应 | Vanner, R. J. | N/A | Hematopoietic Tet2 inactivation enhances the response to checkpoint blockade immunotherapy | |
| 卵巢癌中与年龄相关的脂质代谢调控 | Feng, J. | N/A | Regulation of Age-Related Lipid Metabolism in Ovarian Cancer | |
| EB-SUN，果蝇中一种新的微管正端追踪蛋白。 | Kim, S. K. | N/A | EB-SUN, a New Microtubule Plus-End Tracking Protein in Drosophila. | |
| 衰老小鼠各组织的自噬作用 | Carosi, J. M. | N/A | Autophagy across tissues of aging mice | |
| 具有截短的Cas12a结合序列的单链HDR模板提高了在原代人T细胞中的敲入效率 | Nitulescu, A.-M. | N/A | Single-stranded HDR templates with truncated Cas12a binding sequences improve knock-in efficiencies in primary human T cells | |
| 一种在鲍曼不动杆菌中协调肽聚糖周转并激活细胞分裂酰胺酶的保守枢纽蛋白 | Simpson, B. W. | N/A | A conserved hub protein for coordinating peptidoglycan turnover that activates cell division amidases in Acinetobacter baumannii | |
| 一种基于微孔板读取器的高通量方法，用于在没有流式细胞术的情况下监测体外HIV潜伏逆转 | Nkwelle, C. E. | N/A | A high-throughput, microplate reader-based method to monitor in vitro HIV latency reversal in the absence of flow cytometry | |
| 鉴定影响CRISPR相关转座酶的蛋白质以增强基因组编辑 | Song, L. | N/A | Identification of Proteins Influencing CRISPR-Associated Transposases for Enhanced Genome Editing | |
| PathMHC：一种工作流程，用于在疫苗靶点识别的发现性免疫肽组学实验中选择性靶向病原体衍生的MHC肽段 | Leddy, O. | N/A | PathMHC: a workflow to selectively target pathogen-derived MHC peptides in discovery immunopeptidomics experiments for vaccine target identification | |
| 延伸因子P调控沙门氏菌抗生素抗性基因的核糖体移码 | Baek, S. | N/A | Elongation factor P controls ribosomal frameshift of a Salmonella antimicrobial resistance gene | |
| 利用果聚糖的γ-变形菌中的SusC/D样蛋白 | Zuehlke, M.-K. | N/A | SusC/D-like proteins in Gammaproteobacteria that utilize fructans | |
| IGF1R在肺炎球菌性肺炎中具有保护作用 | Felten, M. | N/A | IGF1R is protective in pneumococcal pneumonia | |
| SRY-Box转录因子9通过解除转录抑制因子CCAAT/增强子结合蛋白β的抑制作用，调控3'-磷酸腺苷5'-磷酸硫酸合成酶2 mRNA的表达。 | Liu, C. | N/A | SRY-Box Transcription Factor 9 regulates 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 2 mRNA expression through derepression of the transcriptional repressor, CCAAT/enhancer-binding protein beta | |
| 基因组方法研究克雷伯氏肺炎杆菌临床分离株中CRISPR/Cas系统与多药耐药性之间的关系 | Owaid, H. A. | N/A | Genomic approach to studying the relationship between the CRISPR/Cas system and multidrug resistance in clinical isolates of Klebsiella pneumoniae | |
| 通过化学标记实现细胞蛋白激酶活性的分子记录 | Sun, D.-e. | N/A | Molecular recording of cellular protein kinase activity with chemical labeling | |
| 单个远端突变通过稳定PET结合增强已知PETase的活性 | Fu, X. | N/A | Single Distal Mutation Enhances Activity of known PETases via Stabilisation of PET-binding | |
| CRISPR编辑影响甲型流感病毒感染的候选宿主因子 | Kyawe, P. P. | N/A | CRISPR editing of candidate host factors that impact influenza A virus infection | |
| 组蛋白甲基转移酶DOT1B对于利什曼原虫（Leishmania mexicana）的阶段分化和巨噬细胞感染并非必需。 | Eisenhuth, N. | N/A | The histone methyltransferase DOT1B is dispensable for stage differentiation and macrophage infection in Leishmania mexicana | |
| 父母照顾对毒蛙皮肤微生物群落组成的影响 | Fischer, M.-T. | N/A | Effects of parental care on skin microbial community composition in poison frogs | |
| 利用病毒RNA加工的阿喀琉斯之踵开发新型抗病毒药物 | Zahedi Amiri, A. | N/A | Exploiting the Achilles' Heel of Viral RNA Processing to Develop Novel Antivirals | |
| 在磷酸盐限制条件下，阿米诺脂的生物合成促进了鲍曼不动杆菌对粘菌素的耐药性。 | Olea-Ozuna, R. J. | N/A | Aminolipid biosynthesis in response to phosphate limitation promotes colistin tolerance in Acinetobacter baumannii | |
| 一项针对挪威肺炎克雷伯菌的全基因组“一个健康”研究揭示了重叠的菌群，但近期在不同宿主间的传播事件较少。 | Hetland, M. A. K. | N/A | A genome-wide One Health study of Klebsiella pneumoniae in Norway reveals overlapping populations but few recent transmission events across reservoirs | |
| 共生体的丧失和获得，而非共同多样化，塑造了蜜蜂肠道微生物群的多样性和功能。 | Prasad, A. | N/A | Symbiont loss and gain, rather than co-diversification shapes honeybee gut microbiota diversity and function | |
| 预防脑膜炎奈瑟菌鼻咽部定植依赖于抗体调理和中性粒细胞的吞噬作用。 | Currie, E. G. | N/A | Protection against Neisseria meningitidis nasopharyngeal colonization relies on antibody opsonization and phagocytosis by neutrophils | |
| 抗生素诱导的形态变化增强噬菌体捕食：结构化环境中噬菌斑形成的数学模型 | Bulssico, J. | N/A | Antibiotic-Induced Morphological Changes Enhance Phage Predation: A Mathematical Model of Plaque Formation in Structured Environments | |
| flt1失活通过增强内皮细胞活性并限制纤维化反应，促进斑马鱼心脏再生。 | Wang, Z. | N/A | flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response | |
| 多重纳米孔扩增子测序用于区分抗疟药物试验中的复发与新感染 | Holzschuh, A. | N/A | Multiplexed nanopore amplicon sequencing to distinguish recrudescence from new infection in antimalarial drug trials | |
| 工程变体AAV滴定中热稳定性的作用 | Zin, E. A. | N/A | The Role of Thermal Stability in AAV Titration of Engineered Variants | |
| HIV Vpr通过激活一种核仁特异性的ATR途径来降解核仁应激传感器CCDC137 | Nisson, K. A. | N/A | HIV Vpr activates a nucleolar-specific ATR pathway to degrade the nucleolar stress sensor CCDC137 | |
| 跨膜糖蛋白Gpnmb在斑马鱼心脏再生过程中的免疫和纤维化反应中是必需的。 | Gupta, S. | N/A | The transmembrane glycoprotein Gpnmb is required for the immune and fibrotic responses during zebrafish heart regeneration | |
| RNA解旋酶HrpA在E. coli中解救碰撞的核糖体 | Campbell, A. | N/A | The RNA helicase HrpA rescues collided ribosomes in E. coli | |
| 尿酸通过天然人URAT1转运的分子机制及其被抗痛风药物抑制的机制 | Wu, C. | N/A | Molecular mechanisms of uric acid transport by the native human URAT1 and its inhibition by anti-gout drugs | |
| 不受海马体尖波涟漪调节的前额叶皮质内侧神经元参与空间调谐及即将做出的选择信号传递。 | den Bakker, H. | N/A | Neurons in the medial prefrontal cortex that are not modulated by hippocampal sharp-wave ripples are involved in spatial tuning and signaling upcoming choice. | |
| 小脑-丘脑神经元在学习及小鼠运动技能离线巩固中的多重功能 | Varani, A. | N/A | Multiple Functions of Cerebello-Thalamic Neurons in Learning and Offline Consolidation of a Motor Skill in mice. | |
| 听觉皮层结构与阅读技能的代际传递 | Kepinska, O. | N/A | Intergenerational transmission of the structure of the auditory cortex and reading skills | |
| 斑马鱼模型揭示人类基因SRGAP2在神经胶质细胞和视觉系统发育中的新功能 | Uribe-Salazar, J. M. | N/A | Zebrafish models of human-duplicated gene SRGAP2 reveal novel functions in microglia and visual system development | |
| 高数据率大分子晶体学（HDRMX）的大规模压缩：对衍射数据及后续结构分析的影响 | Bernstein, H. J. | N/A | Massive Compression for High Data Rate Macromolecular Crystallography (HDRMX): Impact on Diffraction Data and Subsequent Structural Analysis | |
| NAPE-PLD基因的缺失在小鼠中引发了情境依赖性的焦虑样行为、应激反应及下丘脑-垂体-肾上腺轴功能的失调。 | Woodward, T. J. | N/A | Genetic deletion of NAPE-PLD induces context-dependent dysregulation of anxiety-like behaviors, stress responsiveness, and HPA-axis functionality in mice | |
| 海马苔藓纤维突触处突触前易化的废除影响神经元集合活动和空间记忆 | Marneffe, C. | N/A | Abrogation of presynaptic facilitation at hippocampal mossy fiber synapses impacts neural ensemble activity and spatial memory | |
| 玩耍行为的转录组在幼年大鼠内侧杏仁核中表现出性别偏向：抑制性神经元的作用 | Marquardt, A. E. | N/A | The transcriptome of playfulness is sex-biased in the juvenile rat medial amygdala: a role for inhibitory neurons | |
| 中性粒细胞特异性STING在心肌缺血/再灌注损伤中的心脏保护作用 | Brockman, M. L. | N/A | The Cardioprotective Role of Neutrophil-Specific STING in Myocardial Ischemia/Reperfusion Injury | |
| Axin1和Axin2调控WNT信号通路，以促进不同的中胚层发育程序 | Hernandez-Martinez, R. | N/A | Axin1 and Axin2 regulate the WNT-signaling landscape to promote distinct mesoderm programs | |
| IgSF蛋白DIP-α和Dpr10的关键亲和窗口对于适当的运动神经元树突化是必需的。 | Lopez, D. | N/A | A critical affinity window for IgSF proteins DIP-α and Dpr10 is required for proper motor neuron arborization | |
| 将环斑海豹的觅食行为与环境变化联系起来 | Nykänen, M. | N/A | Linking ringed seal foraging behaviour to environmental variability | |
| 广泛存在的自然变异人类外显子有助于遗传学解释 | Jacobs, H. | N/A | Widespread naturally variable human exons aid genetic interpretation | |
| # BioRxiv 2024-09-10 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 神经元中异染色质长期丧失后，伴随胶质细胞反应和认知能力下降 | Newman, A. G. | N/A | Glial Reactivity and Cognitive Decline Follow Chronic Heterochromatin Loss in Neurons | |
| intSDM：一个用于构建可重复性工作流的综合物种分布模型领域的R包 | Mostert, P. S. | N/A | intSDM : an R package for building a reproducible workflow for the field of integrated species distribution models | |
| 进化上多样化的真菌游动孢子展现出特定的游泳模式，这些模式与其超微结构密切相关。 | Galindo, L. J. | N/A | Evolutionarily diverse fungal zoospores show contrasting swimming patterns specific to ultrastructure | |
| 海马体中扩展记忆表征的形成 | Vaidya, S. P. | N/A | The formation of an expanding memory representation in the hippocampus | |
| 突触可塑性的结构影响：突触前连接在E/I共调谐出现中的作用 | Giannakakis, E. | N/A | Structural influences on synaptic plasticity: the role of presynaptic connectivity in the emergence of E/I co-tuning | |
| 内源性病毒元件构成了个性化癌症疫苗抗原的补充来源。 | Garde, C. | N/A | Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines | |
| 植入前胚胎放大了压力诱导的精子衍生miRNA含量的变化，以介导跨代表观遗传继承 | Champroux, A. | N/A | Preimplantation Embryos Amplify Stress-Induced Changes in Sperm-Derived miRNA Content to Mediate Transgenerational Epigenetic Inheritance | |
| 在人类细胞中发现微小RNA衍生的RNA和蛋白质 | Huang, X. | N/A | Discovery of microsized RNA-derived RNAs and proteins in human cells | |
| 改善焦虑研究：通过多状态总结测量的新方法揭示特质焦虑 | Varga, Z. K. | N/A | Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states | |
| 脑膜炎症的空间转录组学揭示了邻近脑实质中的炎症基因特征 | Gadani, S. | N/A | Spatial Transcriptomics of Meningeal Inflammation Reveals Inflammatory Gene Signatures in Adjacent Brain Parenchyma | |
| 硒代半胱氨酸tRNA甲基化促进黑色素瘤转移中氧化应激的抵抗力 | Nease, L. A. | N/A | Selenocysteine tRNA methylation promotes oxidative stress resistance in melanoma metastasis | |
| 在运动执行和运动规划过程中，控制策略可以根据任务需求进行调整。 | Orban de Xivry, J.-J. | N/A | A control policy can be adapted to task demands during both motor execution and motor planning | |
| 用于工业碳捕获和利用的大规模培养海洋硅藻的生物反应器微生物组 | Aalto, N. J. | N/A | The bioreactor microbiome of mass cultivated marine diatoms for industrial carbon capture and utilization | |
| eIF3与高度翻译的mRNA的3'-UTR末端结合 | Mestre-Fos, S. | N/A | eIF3 engages with 3'-UTR termini of highly translated mRNAs | |
| 低盐度显著改变了海洋基础物种昆布（Saccharina latissima，糖海带）的细菌群落。 | Schenk, S. | N/A | Low salinity significantly alters the bacterial community of the marine foundation species Saccharina latissima (sugar kelp) | |
| 肌动蛋白动力学调控卵黄囊内脏内胚层细胞中两种不同的内体融合模式 | Koike, S. | N/A | Actin dynamics switches two distinct modes of endosomal fusion in yolk sac visceral endoderm cells | |
| 港海豹（Phoca vitulina）的触须空间排列与小鼠（Mus musculus）和大鼠（Rattus norvegicus）的触须排列比较 | Graff, M. M. | N/A | Spatial arrangement of the whiskers of harbor seals (Phoca vitulina) compared to whisker arrangements of mice (Mus musculus) and rats (Rattus norvegicus) | |
| AKAP/AC纳米域上钙-cAMP振荡的时空协调受一个不连贯前馈环路的调控。 | Qiao, L. | N/A | Spatiotemporal orchestration of calcium-cAMP oscillations on AKAP/AC nanodomains is governed by an incoherent feedforward loop | |
| 牛磺酸泛基因组揭示了与白头牛脱色素相关的KIT上游的片段重复 | Milia, S. | N/A | Taurine pangenome uncovers a segmental duplication upstream of KIT associated with depigmentation in white-headed cattle | |
| 在Hydra水螅的头再生过程中，Notch信号传导是介导两个模式形成过程所必需的。 | Steichele, M. | N/A | Notch-signaling is required for mediating between two pattern forming processes during head regeneration in Hydra polyps | |
| 从质量加权浓度分布的矩差推断代谢通量 | Tuobang, L. | N/A | Infer metabolic fluxes from moment differences of mass-weighted concentration distributions | |
| 在人工耳蜗植入儿童中神经语音跟踪的恢复力和脆弱性 | Federici, A. | N/A | Resilience and vulnerability of neural speech tracking in children with cochlear implants | |
| 盐度耐受性的昼夜调节：Vigna marina中SOS途径和钠排泄的昼夜调控机制 | Noda, Y. | N/A | Diurnal regulation of SOS Pathway and Sodium Excretion Underlying Salinity Tolerance of Vigna marina | |
| 果蝇中性别特异性行为的昼夜节律控制 | Franco, D. L. | N/A | Circadian control of a sex-specific behaviour in Drosophila | |
| 解决二聚体形式的途径将肠杆菌科中的质粒与巨型质粒区分开来。 | Fournes, F. | N/A | The pathway to resolve dimeric forms distinguishes plasmids from megaplasmids in Enterobacteriaceae | |
| 用于延时摄像机监测昆虫及其花卉环境的一个深度学习流程 | Bjerge, K. | N/A | A deep learning pipeline for time-lapse camera monitoring of insects and their floral environments | |
| 一种血清素类致幻剂的双受体模型 | Juliani, A. | N/A | A dual-receptor model of serotonergic psychedelics | |
| 单细胞RNA测序揭示的Wilson病中自然杀伤细胞耗竭预测胆囊炎的预后 | Jin, Y. | N/A | NK Cell Exhaustion in Wilson's Disease Revealed by Single-cell RNA Sequencing Predicts the Prognosis of Cholecystitis | |
| 前颞区双向连接性的变化反映了多声部音乐中的图形-背景反转 | Kim, C. H. | N/A | Bidirectional connectivity changes in the frontotemporal areas reflect figure-ground reversal in multivoiced music | |
| 用于纵向微生物组研究的微生物网络推断方法——LUPINE | Kodikara, S. | N/A | Microbial network inference for longitudinal microbiome studies with LUPINE | |
| 防御反应中小分泌肽信号的比较分析：来自维管植物和非维管植物的见解 | Lyapina, I. | N/A | Comparative Analysis of Small Secreted Peptide Signaling during Defense Response: Insights from Vascular and Non-Vascular Plants | |
| 人类出生组织产品作为非阿片类药物抑制术后疼痛 | Zhang, C. | N/A | Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain | |
| 人类皮层下听觉异常检测：一项ABR研究 | Wetekam, J. | N/A | Subcortical Auditory Deviance Detection in Humans: An ABR Study | |
| 双组分信号决定哪些锈菌分泌的蛋白质被转运到寄主植物细胞中 | Lawrence, G. J. | N/A | A two-component signature determines which rust fungi secreted proteins are translocated into the cells of the host plant | |
| 来自帕金森病患者iPSCs的LRRK2-G2019S突变衍生的少突胶质前体细胞的单细胞转录组变化 | Dehestani, M. | N/A | Single-cell transcriptomic changes in oligodendroglial lineage cells derived from Parkinson's disease patient-iPSCs with LRRK2-G2019S mutation | |
| 一种新出现的PB2-627多态性通过突破哺乳动物和禽类宿主中的ANP32限制，增强了禽流感病毒的大流行潜力。 | Guo, Y. | N/A | An emerging PB2-627 polymorphism increases the pandemic potential of avian influenza virus by breaking through ANP32 host restriction in mammalian and avian hosts | |
| 年轻鱼类的肖像：从东格陵兰早三叠纪的幼体标本重新描述Pteronisculus gunnari (Nielsen, 1942)，并探讨其对早期辐鳍鱼类个体发育的影响 | Cavicchini, I. | N/A | A Portrait of a Young Fish: Redescription of Pteronisculus gunnari (Nielsen, 1942) from a juvenile specimen from the Early Triassic of East Greenland, with implications for ontogenetic development in early actinopterygians | |
| 质粒病毒维持能够使细菌种群从感染中恢复，并实现病毒与细菌的共存。 | Sanchez-Martinez, R. | N/A | Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence | |
| 动物基因组结构的保守性是例外，而非普遍规律。 | Lewin, T. D. | N/A | Conservation of animal genome structure is the exception not the rule | |
| 厌氧消化共生体中关键功能种群的代谢隔离与特征基因簇 | Wang, Y. | N/A | Metabolic Segregation and Characteristic Gene clusters of the Key Functional Populations in Anaerobic Digestion Consortia | |
| 重新评估社会排斥的神经相关性：一项使用动脉自旋标记技术的网络球范式复制研究 | Labek, K. | N/A | Reassessing the Neural Correlates of Social Exclusion: A Replication Study of the Cyberball Paradigm Using Arterial Spin Labelling | |
| 用于日本脑炎和西尼罗病毒的感染性亚基因组扩增子策略 | Singh, P. P. | N/A | Infectious subgenomic amplicon strategies for Japanese encephalitis and West Nile viruses | |
| 雄性和雌性小鼠分别与同性和异性同类形成了更强的社会性厌恶记忆。 | Beaver, J. N. | N/A | Male and female mice respectively form stronger social aversive memories with same and different sex conspecifics | |
| 纤维素涂料：一类淀粉样蛋白靶向肽 | Pedrola, J. A. | N/A | Fibril Paint: a class of amyloid-targeting peptides | |
| 从头设计Ras同工型选择性结合剂 | Zhang, J. Z. | N/A | De novo design of Ras isoform selective binders | |
| 重新审视假单胞菌质粒的不相容性群组：对R质粒及其复制子的综合分析 | Nishimura, Y. | N/A | Incompatibility groups of Pseudomonas plasmids revisited: comprehensive analysis of R-factors and their replicons | |
| 在患者层面建模意识障碍揭示了网络对诊断的影响与局部节点参数在预后中的作用 | Zonca, L. | N/A | Modeling disorders of consciousness at the patient level reveals the network's influence on the diagnosis vs the local node parameters role in prognosis | |
| 基因组变化在同属物种对之间是多样的 | Francis, W. R. | N/A | Genomic changes are varied across congeneric species pairs | |
| 脂联素信号在调节小鼠对脂肪味觉的反应中起作用。 | Lin, F. | N/A | Adiponectin signaling modulates fat taste responsiveness in mice | |
| 远程缺血预处理通过CD36介导的吞噬作用减轻跨神经元变性并促进中风恢复。 | Ju, H. | N/A | Remote ischemic conditioning attenuates transneuronal degeneration and promotes stroke recovery via CD36-mediated efferocytosis. | |
| 威尔姆斯瘤中亚型特异性进化模式及临床相关基因组不稳定性的研究 | Cresswell, G. D. | N/A | Subtype-specific Patterns of Evolution and Clinically Relevant Genomic Instability in Wilms Tumour | |
| sTREM2的柔性茎域调节其与脑内磷脂的相互作用 | Saeb, D. | N/A | The flexible stalk domain of sTREM2 modulates its interactions with phospholipids in the brain | |
| 人类和蝙蝠基因组在COSMIC突变特征下的稳健性 | Song, J.-H. | N/A | Human and bats genome robustness under COSMIC mutational signatures | |
| 结核分枝杆菌拓扑异构酶I在C端缺失后能量上受到严重影响 | Balthrop, D. | N/A | Mycobacterial Topoisomerase I Energetically Suffers From C-Terminal Deletions | |
| 促性腺激素细胞具有双重起源，其中大多数在微青春期期间源自垂体干细胞。 | Sheridan, D. | N/A | Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty. | |
| 胞外囊泡通过将ATP合成转运至伪足并激活整合素粘附复合物，调控淋巴管平滑肌瘤细胞的亚稳态表型。 | Kalvala, A. K. | N/A | Extracellular vesicles regulate metastable phenotypes of lymphangioleiomyomatosis cells via shuttling ATP synthesis to pseudopodia and activation of integrin adhesion complexes. | |
| SAF-A SAP结构域在X染色体失活、转录、剪接和细胞增殖中的作用 | Sharp, J. A. | N/A | Role of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation | |
| 三种自闭症谱系障碍亚型及其转录组特征：基于形态学相似性网络的推导 | Jiang, H. | N/A | Three Subtypes Of Autism Spectrum Disorder With Transcriptomic Signatures Derived From Morphometric Similarity Networks | |
| 胚胎增强子元件的表观遗传启动协调发育基因网络 | Todd, C. D. | N/A | Epigenetic priming of embryonic enhancer elements coordinates developmental gene networks | |
| 腹侧被盖区多巴胺神经活动与前额叶皮层和海马体中的规则表征同时切换 | Ding, M. | N/A | Ventral tegmental area dopamine neural activity switches simultaneously with rule representations in the prefrontal cortex and hippocampus | |
| 行为状态和刺激强度调节生长抑素中间神经元在稳定网络活动中的作用 | Cammarata, C. M. | N/A | Behavioral state and stimulus strength regulate the role of somatostatin interneurons in stabilizing network activity | |
| 早期生活压力影响小鼠的癫痫结果 | Coleman, E. M. | N/A | Early life stress influences epilepsy outcomes in mice | |
| 早期精神病患者灰质和白质中的神经突密度和自由水 | Van Dyken, P. C. | N/A | Neurite Density and Free Water in the Gray and White Matter of Early Psychosis Patients | |
| 人类小脑中浦肯野细胞树突的非等比扩展及增强的区室化 | Busch, S. E. | N/A | Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum | |
| 具身视角：角回和楔前叶在自然事件记忆中解码自我 | Iriye, H. | N/A | An embodied perspective: angular gyrus and precuneus decode selfhood in memories of naturalistic events | |
| 在发育中的新皮质中，Rbfox1/2/3对转录调节因子和Ptbp1的细胞类型特异性剪接 | Ruan, X. | N/A | Cell-type-specific splicing of transcription regulators and Ptbp1 by Rbfox1/2/3 in the developing neocortex | |
| 在过去500万年间，气候环境对人类脑容量的影响 | Nicholson, S. L. | N/A | Climatic-environmental influences on hominin brain size over the last 5 million years | |
| THz电磁场对离子通道影响的模拟协议 | Xue, L. | N/A | Protocol for Simulating the Effect of THz Electromagnetic Field on Ion Channels | |
| 自闭症谱系障碍的Shank3-/-小鼠模型中前额叶回路功能障碍的发展进程 | Devienne, G. | N/A | Developmental progression of prefrontal circuit dysfunction in a Shank3-/- mouse model of autism spectrum disorder | |
| TMPRSS6 切割 KCNE1 并在铁超载疾病中引发心律失常 | Peischard, S. | N/A | TMPRSS6 cleaves KCNE1 and causes arrhythmias in iron overload disease | |
| 生酮干预措施能恢复认知功能并调节阿尔茨海默病小鼠模型中的外周代谢紊乱。 | M'Bra, P. E. H. | N/A | Ketogenic interventions restore cognition and modulate peripheral metabolic dysfunctions in Alzheimer's disease mouse models | |
| 肥大细胞促进结核病病理和易感性 | Gupta, A. | N/A | Mast cells promote pathology and susceptibility in tuberculosis | |
| HIV-1包膜可变区1中罕见的双半胱氨酸残基与中和逃逸及广谱性发展相关联 | Hesselman, M. C. | N/A | Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development | |
| 解析TLR4和性别对慢性酒精摄入引起的细胞外囊泡脂质组失调的影响 | Perpina-Clerigues, C. | N/A | Unravelling the impact of TLR4 and sex on chronic alcohol consumption-induced lipidome dysregulation in extracellular vesicles | |
| Rad18在维持胶质母细胞瘤增殖中的一种非催化功能 | Benbahouche, N. E.-H. | N/A | A non-catalytic function for Rad18 in sustaining glioblastoma proliferation | |
| 近乎完整的鬃狮蜥（Pogona vitticeps）基因组组装为揭示鬃狮蜥性染色体的起源提供了洞见。 | Guo, Q. | N/A | A near-complete genome assembly of the bearded dragon Pogona vitticeps provides insights into the origin of Pogona sex chromosomes | |
| 天堂鱼（Macropodus opercularis）作为情感和认知功能的新型转化模型 | Varga, Z. K. | N/A | Paradise fish (Macropodus opercularis) as novel translational model for emotional and cognitive function | |
| 通过贝叶斯优化和深度学习实现复杂癌细胞球的高分辨率单细胞分割 | Mogollon, I. | N/A | Achieving high-resolution single-cell segmentation in convoluted cancer spheroids via Bayesian optimization and deep-learning | |
| 胶质瘤中CD200的耗竭增强了抗肿瘤免疫并诱导了肿瘤排斥 | Raphael, I. | N/A | CD200 depletion in glioma enhances antitumor immunity and induces tumor rejection | |
| 跨环境与依赖情境的互侵入性下，从菌株频率数据中推断成对相互作用的嵌套推断 | Le, T. M. T. | N/A | Nested inference of pairwise interactions from strain frequency data across settings and context-dependent mutual invasibilities | |
| 美国东南部两种蚂蚁的行为互动及本地超级蚁群的证据 | Kanwar, S. | N/A | Behavioral Interactions in Two Ant Species in The Southeast United States and Evidence for a Native Supercolony | |
| 胆固醇在M2簇集和病毒出芽中的作用解析 | Kolokouris, D. | N/A | The Role of Cholesterol in M2 Clustering and Viral Budding Explained | |
| FGFR2促进对ALK酪氨酸激酶抑制剂的耐药性，其抑制作用与lorlatinib联合使用在治疗表达ALK的神经母细胞瘤中具有协同效应。 | Pucci, P. | N/A | FGFR2 promotes resistance to ALK tyrosine kinase inhibitors and its inhibition acts synergistically with lorlatinib in the treatment of ALK-expressing neuroblastoma | |
| 分布式学习驱动统计性聋化 | Luthra, S. | N/A | Distributional learning drives statistical deafening | |
| 解决功能性神经成像中的不一致性：一种可复现的数据驱动多尺度功能图谱，用于典型脑网络 | Jensen, K. M. | N/A | Addressing inconsistency in functional neuroimaging: A replicable data-driven multi-scale functional atlas for canonical brain networks | |
| 弓形虫细胞周期检查点激酶的特征分析 | Johnson, M. K. | N/A | Characterisation of cell cycle checkpoint kinases in Toxoplasma gondii | |
| 一些人工智能工具在针对猫传染性腹膜炎病毒（FIPV）主要病毒蛋白酶的某些化合物药物设计中的应用 | Khan, M. Y. | N/A | Applications of some artificial intelligence tools in the drug design of some compounds targeting the main viral protease of the Feline Infectious Peritonitis Virus (FIPV) in cats | |
| 蝾螈表观遗传时钟提供了对可忽略衰老本质的见解。 | Haluza, Y. | N/A | Axolotl epigenetic clocks offer insights into the nature of negligible senescence | |
| 染色质重塑因子DEK促进乳腺上皮细胞的增殖，并与H3K27me3表观遗传修饰相关。 | Johnstone, M. | N/A | The chromatin remodeler DEK promotes proliferation of mammary epithelium and is associated with H3K27me3 epigenetic modifications | |
| 无意义错误的重要性：估计蛋白质合成过程中脱落错误的速率及其影响 | Cope, A. L. | N/A | The Importance of Nonsense Errors: Estimating the Rate and Implications of Drop-Off Errors during Protein Synthesis | |
| 海洋捕食性蜗牛毒液生产的演化 | Zancolli, G. | N/A | Evolution of venom production in marine predatory snails | |
| FishPi：一种生物信息学预测工具，用于在斑马鱼中关联piRNA和转座元件 | Godden, A. M. | N/A | FishPi: a bioinformatic prediction tool to link piRNA and transposable elements in zebrafish | |
| 黑水虻的控制性多配交配：通过数量遗传设计推进育种计划 | Jensen, K. | N/A | Controlled and polygynous mating in the black soldier fly: advancing breeding programs through quantitative genetic designs | |
| RNA聚合酶II和III招募到snRNA启动子的不同机制的结构见解 | Shah, S. Z. | N/A | Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters | |
| scDrugAtlas：一个综合性的单细胞药物反应图谱，用于揭示治疗效果中的肿瘤异质性 | Huang, W. | N/A | scDrugAtlas: an integrative single-cell drug response atlas for unraveling tumor heterogeneity in therapeutic efficacy | |
| 皮肤成纤维细胞异质性的共识单细胞转录组图谱 | Ascension, A. M. | N/A | A consensus single-cell transcriptomic atlas of dermal fibroblast heterogeneity | |
| 使用Exeter Multiscope自动测量心肌细胞单层收缩 | Corbett, A. D. | N/A | Automated measurement of cardiomyocyte monolayer contraction using the Exeter Multiscope | |
| LYMTACs：嵌合小分子重新利用溶酶体膜蛋白实现目标蛋白的重新定位与降解 | Nalawansha, D. A. | N/A | LYMTACs: Chimeric Small Molecules Repurpose Lysosomal Membrane Proteins for Target Protein Relocalization and Degradation | |
| 两种非小细胞肺癌亚型之间转录组和蛋白质组表达的比较分析 | Nicholas, B. | N/A | Comparative analysis of transcriptomic and proteomic expression between two non-small cell lung cancer subtypes | |
| 赖氨酰氧化酶对小鼠子宫肌层收缩力和及时分娩是必要的 | Ouellette, A. | N/A | Lysyl Oxidases are Necessary for Myometrial Contractility and On-Time Parturition in Mice | |
| 左心房应变作为压力超负荷小鼠模型中心脏功能障碍的预测因子 | Salvas, J. P. | N/A | Left Atrial Strain as a Predictor of Cardiac Dysfunction in a Murine Model of Pressure Overload | |
| ERC1的生物分子凝聚招募ATG8和NBR1，驱动自噬小体的形成，以促进植物的热耐受性。 | Chung, K. K. | N/A | Biomolecular condensation of ERC1 recruits ATG8 and NBR1 to drive autophagosome formation for plant heat tolerance | |
| 尽管四维流磁共振成像（4D flow MRI）中存在非正态误差，心血管数字孪生中的不确定性：识别可靠的生物标志物，如心室舒张率 | Tunedal, K. | N/A | Uncertainty in cardiovascular digital twins despite non-normal errors in 4D flow MRI: identifying reliable biomarkers such as ventricular relaxation rate | |
| 通过电影驱动的超高场fMRI识别人类和小猕猴大脑网络中的功能同源体 | Zanini, A. | N/A | Identifying Functional Homologues in Human and Marmoset Brain Networks via Movie-Driven Ultra-High Field fMRI | |
| 啮齿动物连续表现测试中与任务时间相关的性能下降并非由任务中的身体脱离引起。 | Li, Y. | N/A | Time-on-task-related decrements in performance in the rodent continuous performance test are not caused by physical disengagement from the task | |
| 评估用于人类脊髓非侵入性电生理学的噪声校正方法 | Bailey, E. | N/A | Evaluating noise correction approaches for non-invasive electrophysiology of the human spinal cord | |
| 任务时间越长，注视漂移增加 | Friedman, L. | N/A | Fixation Drift Increases as a Function of Time-on-Task | |
| 新近习得的词语-动作关联在运动准备期间触发听觉皮层激活：对动作词语学习中的赫布可塑性的启示 | Tretyakova, V. | N/A | Newly Acquired Word-Action Associations Trigger Auditory Cortex Activation During Movement Preparation: Implications for Hebbian Plasticity in Action Words Learning | |
| 单侧手部肌肉收缩对内在奖励情境下额叶alpha不对称性和抑制控制的影响：一项随机对照试验 | Akil, A. M. | N/A | The effect of unilateral hand muscle contraction on frontal alpha asymmetry and inhibitory control in intrinsic reward contexts, a randomized controlled trial | |
| 从视觉皮层活动的动态估计注意力场 | Bloem, I. M. | N/A | Dynamic estimation of the attentional field from visual cortical activity | |
| 跨突触IgLON黏附分子复合物直接接触并聚集烟碱型受体 | Mialon, M. | N/A | A trans-synaptic IgLON adhesion molecular complex directly contacts and clusters a nicotinic receptor | |
| β2-肾上腺素能偏向激动剂以NF-κB依赖的方式抑制Th17的发育及记忆Th17细胞的反应。 | Hajiaghayi, M. | N/A | β2-Adrenergic Biased Agonist Inhibits the Development of Th17 and the Response of Memory Th17 Cells in an NF-κB-Dependent Manner. | |
| 免疫细胞对弥漫性大B细胞淋巴瘤的影响：孟德尔随机化分析 | He, H. | N/A | Immune Cell Influence on Diffuse Large B-Cell Lymphoma: A Mendelian Randomization Analysis | |
| 通过数字空间分析确定的原发性子宫癌肉瘤中肿瘤间和肿瘤内异质性免疫表现 | Li, Y. | N/A | Inter- and intra-tumor heterogeneous immune presentation in primary uterine carcinosarcoma determined by digital spatial profiling | |
| 基因编码的FerriTag作为冷冻电子断层扫描的特异性标记 | Wang, C. | N/A | Genetically Encoded FerriTag as a Specific Label for Cryo-Electron Tomography | |
| 两个世纪以来环境变化中植物-真菌共生现象的日益普遍 | Fowler, J. C. | N/A | Increasing prevalence of plant-fungal symbiosis across two centuries of environmental change | |
| 生殖干扰能否融入害虫控制的绝育昆虫技术？来自斑翅果蝇Drosophila suzukii的启示 | Cerasti, F. | N/A | Can reproductive interference be integrated into the Sterile Insect Technique for pest control? Insights from the spotted wing fly Drosophila suzukii | |
| 印度鸟类状况2023：利用半结构化公民科学促进鸟类保护的框架 | Viswanathan, A. | N/A | State of India's Birds 2023: A framework to leverage semi-structured citizen science for bird conservation | |
| 小鼠属中不同CD8+ α/β-TCR库的遗传决定因素 | Peters, M. A. | N/A | Genetic determinants of distinct CD8+ α/β-TCR repertoires in the genus Mus | |
| 个人空间与群体灾难中的集体行为 | Lugo, I. | N/A | The personal space and the collective behavior of crowd disasters | |
| 通过分布匹配实现结构脑连接的协调 | Zhou, Z. | N/A | Harmonization of Structural Brain Connectivity through Distribution Matching | |
| 靶向聚合物囊泡可增强损伤后外周神经的递送 | Trumbull, K. | N/A | Targeted Polymersomes Enable Enhanced Delivery to Peripheral Nerves Post-Injury | |
| 一种新型的小鼠前肢生物力学模型在最佳控制模拟的抓取运动中预测肌肉活动 | Gilmer, J. I. | N/A | A novel biomechanical model of the mouse forelimb predicts muscle activity in optimal control simulations of reaching movements | |
| 揭示基于芯片的周围神经系统和中枢神经系统中神经元靶向树枝状聚合物在siRNA递送中的潜力 | Spencer, A. P. | N/A | Unveiling the potential of neuron-targeted dendriplexes for siRNA delivery using a PNS-CNS-on-Chip | |
| 工程化壳聚糖衍生纳米载体用于高效外周和中枢神经元siRNA递送 | Spencer, A. P. | N/A | Engineered chitosan-derived nanocarrier for efficient siRNA delivery to peripheral and central neurons | |
| 利用蛋白质生物信息学深入挖掘免疫肽组学数据集 | Boughter, C. T. | N/A | Utilizing Protein Bioinformatics to Delve Deeper Into Immunopeptidomic Datasets | |
| LLPS REDIFINE 能够对多组分凝聚物进行生物物理特性表征，无需任何标签或标记。 | Novakovic, M. | N/A | LLPS REDIFINE allows the biophysical characterization of multicomponent condensates without tags or labels | |
| 恒温动物体温的分子起源 | Artmann, G. M. | N/A | The molecular origin of body temperature in homeothermic species | |
| 阐明电压门控钠通道中等效门控电荷突变的差异性影响 | Elhanafy, E. | N/A | Elucidating the Differential Impacts of Equivalent Gating-Charge Mutations in Voltage-Gated Sodium Channels | |
| 致癌驱动突变N642H在STAT5B SH2结构域中的结构影响 | Haas-Neill, L. | N/A | The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain | |
| 细胞内核磁共振显示，细胞会选择性地放大和结构重塑淀粉样纤维。 | Ansari, S. | N/A | In cell NMR reveals cells selectively amplify and structurally remodel amyloid fibrils | |
| 探索从热力学稳定和动力学陷阱的枯草杆菌蛋白酶ISP1和SbtE的能量景观的序列和结构决定因素 | Hood, M. R. | N/A | Exploring the sequence and structural determinants of the energy landscape from thermodynamically stable and kinetically trapped subtilisins: ISP1 and SbtE | |
| 多稳态、吸收边界和生长对图灵模式形成的影响 | Oliver Huidobro, M. | N/A | Effects of multistability, absorbing boundaries and growth on Turing pattern formation | |
| 在生长诱导压力下，细胞干质量密度增加。 | Kim, H. | N/A | Intracellular dry mass density increases under growth-induced pressure | |
| 在PET降解酶的共振分配中，操作温度下的核磁共振（NMR） | Gabrielli, V. | N/A | NMR at operational temperature for resonance assignments of a PET degrading enzyme | |
| Zellweger谱系障碍的PEX1-p.Gly844Asp小鼠模型中视网膜色素上皮结构和脂质变化的地理特征。 | Omri, S. | N/A | Geographic characterization of RPE structure and lipid changes in the PEX1-p.Gly844Asp mouse model for Zellweger spectrum disorder. | |
| 发现新型1,4-二羰基硫代半缩氨基脲作为DNA促旋酶抑制剂用于治疗耐甲氧西林金黄色葡萄球菌感染 | Zhang, G. | N/A | Discovery of novel 1,4-dicarbonylthiosemicarbazides as DNA gyrase inhibitors for the treatment of MRSA infection | |
| 个体行为表型的漂移作为应对不可预测世界的策略 | Maloney, R. T. | N/A | Drift in Individual Behavioral Phenotype as a Strategy for Unpredictable Worlds | |
| 在快速眼动睡眠期间，结构化和非结构化的再激活受到新奇体验的调节。 | Choi, J. | N/A | Structured and unstructured reactivations during REM sleep are modulated by novel experiences | |
| 经过训练的腹侧视觉通路深度神经网络模型能够稳健地编码数量信息，而不受物体和场景身份的影响。 | Chapalain, T. | N/A | Trained deep neural network models of the ventral visual pathway encode numerosity with robustness to object and scene identity | |
| 小鼠海马中与年龄相关的转录组和表观遗传变化 | Bilgic, M. | N/A | Age-associated transcriptomic and epigenetic alterations in mouse hippocampus | |
| 高血糖选择性地增加大脑的非氧化葡萄糖消耗，而不影响血流。 | Blazey, T. | N/A | Hyperglycemia selectively increases cerebral non-oxidative glucose consumption without affecting blood flow | |
| 利用扩散磁共振成像绘制人类未定带的地形组织图 | Haast, R. A. | N/A | Mapping the topographic organization of the human zona incerta using diffusion MRI | |
| 放射免疫疗法的差异性反应是由肿瘤微环境的内在特征所决定的。 | Karam, S. D. | N/A | Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment | |
| 硫酸化糖胺聚糖P3R99单克隆抗体的表征及其抗动脉粥样硬化潜力：物理化学和功能性见解 | Valencia, L. M. | N/A | Characterization and Antiatherogenic Potential of P3R99 Monoclonal Antibody Against Sulfated Glycosaminoglycans: Physicochemical and Functional Insights | |
| 活性EB1激增促进双体嗅觉纤毛生长外段中的微管流入 | Agarwal, R. G. | N/A | Active EB1 surges promote tubulin influx into the growing outer segments of the bipartite olfactory cilia in Drosophila | |
| 支链氨基酸代谢是细胞衰老的重要调节因子。 | Aramaki, Y. | N/A | Branched-chain amino acid metabolism is a crucial modulator of cellular senescence | |
| 鉴定新型肌因子及潜在蛋白质靶点，这些因子介导了长期收缩活动诱导的骨骼肌-细胞外囊泡处理后的功能适应 | Obi, P. O. | N/A | Identification of novel myokines and putative protein targets that mediate functional adaptations in response to chronic contractile activity induced skeletal muscle-extracellular vesicle treatment | |
| 一个流体液滴收集了活细胞中微管收缩所产生的力 | Morelli, K. | N/A | A fluid droplet harvests the force generated by shrinking microtubules in living cells | |
| 在数据旅程中学到的教训：从实验到预测激酶亲和力、选择性、多靶点药理学和耐药性的模型 | Lopez-Rios de Castro, R. | N/A | Lessons learned during the journey of data: from experiment to model for predicting kinase affinity, selectivity, polypharmacology, and resistance | |
| 雌性大鼠中存在明显的操作性行为表型及短暂戒断引发的酒精摄入量增加现象 | Pitock, J. R. | N/A | Presence of distinct operant phenotypes and transient withdrawal-induced escalation of operant ethanol intake in female rats | |
| 胶质细胞会多任务处理以弥补邻近胶质细胞的功能障碍。 | Beachum, A. N. | N/A | Glia multitask to compensate for neighboring glial cell dysfunction | |
| 将植物来源的化合物芹菜素重新用于抗衰老流程中的衰老效应 | Zhang, H. | N/A | Repurposing the plant-derived compound apigenin for senomorphic effect in antiaging pipelines | |
| 推算的DNA甲基化在吸烟和生理年龄的关联性上优于测量的位点 | Richmond, A. | N/A | Imputed DNA methylation outperforms measured loci associations with smoking and chronological age | |
| 工程化生长素诱导的降解子系统以实现对生物体生理的可调节体内控制 | Vicencio, J. | N/A | Engineering the auxin-inducible degron system for tunable in vivo control of organismal physiology | |
| 健康小鼠中的司美格鲁肽给药改变了与压力和动机相关的行为 | Moreno, A. | N/A | Semaglutide Administration in Healthy Mice Alters Behaviour Related to Stress and Motivation | |
| CD300f免疫受体是一种小胶质细胞组织损伤传感器，并在脑损伤后调节吞噬作用。 | Negro-Demontel, M. L. | N/A | CD300f immune receptor is a microglial tissue damage sensor and regulates efferocytosis after brain damage | |
| 自身抗原TRIM21（Ro52）在溶细胞死亡后组装促炎性免疫复合物 | Jones, E. L. | N/A | Autoantigen TRIM21 (Ro52) assembles pro-inflammatory immune complexes following lytic cell death | |
| 利用知识图谱理解生态系统：以高致病性禽流感为例的应用 | Robertson, H. | N/A | Understanding Ecological Systems Using Knowledge Graphs: An Application to Highly Pathogenic Avian Influenza | |
| 无血清食品级和复杂培养基生产对培养肉的环境影响 | Takenaka, N. | N/A | Environmental Impacts of Serum-free Food-grade and Complex Culture Medium Production for Cultivated Meat | |
| 海洋储库中生物碳的滞留时间和遗留效应 | Visser, A. W. | N/A | Residence Times and Legacy of Biogenic Carbon in Ocean Reservoirs | |
| 用于乙二醇同化的合成代谢途径优于天然途径 | Feigis, M. | N/A | Synthetic metabolic pathways for ethylene glycol assimilation outperform natural counterparts | |
| 测量人体胸主动脉及主动脉夹层模型中由磁共振弹性成像导出的硬度的可行性研究 | Hirad, A. A. | N/A | Feasibility of Measuring Magnetic Resonance Elastography-derived Stiffness in Human Thoracic Aorta and Aortic Dissection Phantoms | |
| 高眼压对筛板氧合的影响：一项关于猴子的实验-计算联合研究 | Lu, Y. | N/A | Impact of elevated IOP on lamina cribrosa oxygenation; A combined experimental-computational study on monkeys | |
| 比较软组织的连续体模型和直接纤维模型。一个眼生物力学的例子揭示了连续体模型可能会在组织和纤维层面人为地破坏应变。 | He, X. | N/A | Comparing continuum and direct fiber models of soft tissues.An ocular biomechanics example reveals that continuum models may artificially disrupt the strains at both the tissue and fiber levels | |
| FAIR数据点填充器：协作的FAIR化与FAIR数据点的填充 | Wijnbergen, D. | N/A | The FAIR Data Point Populator: collaborative FAIRification and population of FAIR Data Points | |
| 基于云的大规模蛋白质组学队列可扩展分析 | Guturu, H. | N/A | Cloud-enabled Scalable Analysis of Large Proteomics Cohorts | |
| 脂肪细胞前体是乳腺腺体突然退化后维持的受损上皮微环境的主要贡献者。 | Joshi, P. A. | N/A | Adipocyte progenitors are primary contributors to the disrupted epithelial niche that is sustained following abrupt mammary gland involution | |
| 在表达α-平滑肌肌动蛋白的细胞中敲除LRP6，能阻断博莱霉素诱导的肺损伤后的肺部炎症和纤维化。 | Sung, E.-A. | N/A | Ablation of LRP6 in alpha-smooth muscle actin-expressing cells abrogates lung inflammation and fibrosis upon bleomycin-induced lung injury | |
| 脂肪细胞特异性缺失Dbc1并不能重现健康肥胖表型，但提示其对炎症信号的调控作用 | Santos, L. | N/A | Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling | |
| 一种生理学启发的混合CPG/反射控制器，适用于自行车模拟，并能推广到步行 | Severini, G. | N/A | A physiologically inspired hybrid CPG/Reflex controller for cycling simulations that generalizes to walking | |
| 在激活周围神经方面，时间干扰刺激与直接千赫兹刺激之间不存在生物物理学上的区别。 | Opancar, A. | N/A | There is no Biophysical Distinction between Temporal Interference Stimulation and Direct kHz Stimulation for Actuation of Peripheral Nerves | |
| DendroTweaks：一种揭示树突动力学的交互式方法 | Makarov, R. | N/A | DendroTweaks: An interactive approach for unraveling dendritic dynamics | |
| 利用空间转录组学技术揭示人类阿尔茨海默病大脑中的斑块-胶质细胞生态位 | Avey, D. R. | N/A | Uncovering Plaque-Glia Niches in Human Alzheimer's Disease Brains Using Spatial Transcriptomics | |
| 心肌肌球蛋白复合物的神经符号混合模型从其遗传编码中解码可遗传心脏病的结构基础 | Burghardt, T. P. | N/A | Neural-symbolic hybrid model for myosin complex in cardiac ventriculum decodes structural bases for inheritable heart disease from its genetic encoding | |
| 一种用于高度稀疏、高维、成分数据集的半参数多重插补方法 | Sohn, M. B. | N/A | A semi-parametric multiple imputation method for high-sparse, high-dimensional, compositional data | |
| 用于fNIRS脑状态分类的黎曼几何 | Näher, T. | N/A | Riemannian Geometry for the Classification of Brain States with fNIRS | |
| 利用4D Flow MRI-CFD联合框架研究主动脉瓣狭窄引起的心血管血流模式 | Wang, T. | N/A | Investigation of hemodynamic bulk flow patterns caused by aortic stenosis using a combined 4D Flow MRI-CFD framework | |
| 视网膜筛板和胶质层中星形胶质细胞的形态学比较 | Waxman, S. | N/A | Morphological comparison of astrocytes in the lamina cribrosa and glial lamina | |
| 用于电刺激大脑的喷墨打印透明电极 | Matta, R. | N/A | Inkjet-printed transparent electrodes for electrical brain stimulation | |
| SARS-CoV-2主蛋白酶活性位点环的构象空间由配体结合和蛋白质间别构效应决定。 | Lee, E. | N/A | The Conformational Space of the SARS-CoV-2 Main Protease Active Site Loops is Determined by Ligand Binding and Interprotomer Allostery | |
| 果蝇母体向合子过渡期间先锋因子结合动力学的批量级图谱 | Dima, S. S. | N/A | Bulk-level maps of pioneer factor binding dynamics during Drosophila maternal-to-zygotic transition | |
| 莱姆病螺旋体的跨内皮迁移涉及通过涉及Cdc42和Rac1的跨细胞途径作为中间步骤的螺旋体内化过程。 | Alvarez-Olmedo, D. | N/A | Transendothelial migration of the Lyme disease spirochete involves spirochete internalization as an intermediate step through a transcellular pathway that involves Cdc42 and Rac1 | |
| 全生物体的外部微生物组调节了内部共生体的适应性。 | Imchen, M. | N/A | The holobiont's extracellular microbiome modulates the adaptation of an intracellular endosymbiont | |
| 在铜绿假单胞菌中，体内暴露于头孢他啶/阿维巴坦后导致对头孢洛扎/他唑巴坦和亚胺培南/西司他丁/瑞来巴坦耐药的突变 | Rapsinski, G. J. | N/A | Mutations Leading to Ceftolozane/Tazobactam and Imipenem/Cilastatin/Relebactam Resistance During in vivo exposure to Ceftazidime/Avibactam in Pseudomonas aeruginosa | |
| 生物膜粘附蛋白的缺失改变了Desulfovibrio vulgaris Hildenborough的表面附着和细胞策略 | Pickens, C. P. | N/A | Absence of biofilm adhesin proteins changes surface attachment and cell strategy for Desulfovibrio vulgaris Hildenborough | |
| 生物多样性热点地区的小型哺乳动物携带具有流行潜力的病毒 | Feng, Y. | N/A | Small mammals in biodiversity hotspot harbor viruses of epidemic potential | |
| 流感病毒A型高效基因组复制需要NS2及规范启动子序列之外的序列 | Swaminath, S. | N/A | Efficient genome replication in influenza A virus requires NS2 and sequence beyond the canonical promoter | |
| 一个稳定的15成员细菌SynCom在干旱胁迫下促进短柄草的生长 | Yadav, A. | N/A | A stable 15-member bacterial SynCom promotes Brachypodium growth under drought stress | |
| 转录因子Traffic jam在果蝇卵巢中调控体细胞piRNA通路 | Brasset, E. | N/A | The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries | |
| 依赖ATP的染色质凝聚物重塑揭示了两种重塑因子不同的中尺度效应 | Moore, C. M. | N/A | ATP-dependent remodeling of chromatin condensates uncovers distinct mesoscale effects of two remodelers | |
| 肌动蛋白纤维切割和封端的机制：Gelsolin的作用 | Barrie, K. R. | N/A | Mechanism of Actin Filament Severing and Capping by Gelsolin | |
| 一种用于研究染色质中组蛋白H3的圆形工程化sortase | Whedon, S. D. | N/A | A circular engineered sortase for interrogating histone H3 in chromatin | |
| 高度迭代回文序列1（HIP1）通过同源依赖和甲基化依赖的方式提高了聚球藻PCC 7002的转化效率 | Kamoku, C. | N/A | Highly Iterated Palindrome 1 (HIP1) sequence improves Synechococcus sp. PCC 7002 transformation efficiencies in a homology- and methylation-dependent manner | |
| 非洲猪瘟病毒基因MGF_360-4L通过招募线粒体选择性自噬受体SQSTM1降解MDA5，从而抑制干扰素信号传导，对抗先天免疫反应。 | Niu, Q. | N/A | The African Swine Fever Virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses | |
| 两组分系统ArlRS对金黄色葡萄球菌中壁磷壁酸的糖基开关切换至关重要。 | Kuijk, M. M. | N/A | The two-component system ArlRS is essential for wall teichoic acid glycoswitching in Staphylococcus aureus | |
| 维多利亚州考拉中重组考拉逆转录病毒（recKoRV）的高频检测表明KoRV的历史整合 | Legione, A. R. | N/A | A High Frequency of Detection of Recombinant Koala Retrovirus (recKoRV) in Victorian Koalas Suggests Historic Integration of KoRV | |
| 表皮生长因子受体信号调控宿主对侵袭性曲霉病的炎症反应 | Liu, H. | N/A | Epidermal Growth Factor Receptor Signaling Governs the Host Inflammatory Response to Invasive Aspergillosis | |
| 开发了一种竞争性检测方法，用于评估登革病毒血清型在体外适应性，采用优化的血清型特异性qRT-PCR技术。 | Griffon, A.-F. | N/A | Development of a competition assay to assess the in vitro fitness of dengue virus serotypes using an optimized serotype-specific qRT-PCR | |
| 探索褐球藻界：描述南大洋沿岸及实验室培养的南极褐球藻群落微生物群 | Brisbin, M. M. | N/A | Exploring the Phaeosphere: characterizing the microbiomes of Phaeocystis antarctica colonies from the coastal Southern Ocean and laboratory culture | |
| 体内CRISPR筛选鉴定出GRA12作为跨越弓形虫株系和鼠亚种的超越性分泌致病因子 | Torelli, F. | N/A | In vivo CRISPR screens identify GRA12 as a transcendent secreted virulence factor across Toxoplasma gondii strains and mouse subspecies | |
| 抗病毒机制及金刚烷胺类似物对基于M2 S31N药物抗性流感A病毒的持续抑制作用的临床前评估 | Tietjen, I. | N/A | Antiviral Mechanisms and Preclinical Evaluation of Amantadine Analogs that Continue to Inhibit Influenza A Viruses with M2 S31N-Based Drug Resistance | |
| 非模式福赛斯坦纳菌基因缺失条件质粒的开发 | zhou, p. | N/A | Development of a Conditional Plasmid for Gene Deletion in Non-Model Fusobacterium nucleatum strains | |
| 人类CCR4-NOT是一个基因表达的全局调控因子，并且是一种新型逆转录转座子激活的沉默因子。 | Kulkarni, S. | N/A | Human CCR4-NOT is a global regulator of gene expression and is a novel silencer of retrotransposon activation | |
| EPOP通过直接调节酶复合物二聚化，限制PRC2.1对染色质的靶向作用。 | Gong, L. | N/A | EPOP Restricts PRC2.1 Targeting to Chromatin by Directly Modulating Enzyme Complex Dimerization | |
| ALX4二聚体的结构和生化特性分析揭示了疾病等位基因如何影响ALX4功能的新见解 | Cain, B. | N/A | Structural and biochemical characterization of the ALX4 dimer reveals novel insights into how disease alleles impact ALX4 function | |
| 人T细胞白血病病毒的衣壳蛋白是一种潜在的药物靶点。 | Yu, R. | N/A | The Human T-cell Leukemia Virus capsid protein is a potential drug target | |
| 《小鼠AAV趋向性综合图谱》 | Walkey, C. J. | N/A | A Comprehensive Atlas of AAV Tropism in the Mouse | |
| 平滑肌Cxcl12激活与流体诱导的肺动脉高压中的血管重塑相关 | Klouda, T. | N/A | Smooth muscle Cxcl12 activation is associated with vascular remodeling in flow-induced pulmonary hypertension | |
| 真核起始因子eIF4F和eIF4B在闭环形成时促进翻译终止 | Shuvalova, E. | N/A | Eukaryotic initiation factors eIF4F and eIF4B promote translation termination upon closed-loop formation | |
| 一种雄性精液蛋白SFP-1调控秀丽隐杆线虫雌雄同体交配后的寿命和脂肪代谢 | Chen, M. | N/A | A male seminal fluid protein SFP-1 regulates hermaphrodite post-mating longevity and fat metabolism in Caenorhabditis elegans | |
| 高北极地区主要由未被充分描述、基因高度多样的噬菌体所主导。 | Lemieux, A. | N/A | The High Arctic is dominated by uncharacterized, genetically highly diverse bacteriophages | |
| Andexanet alfa在心脏手术中与肝素抵抗的关联：机制与体外视角 | Chabata, C. V. | N/A | Andexanet alfa-associated heparin resistance in cardiac surgery: mechanism and in vitro perspectives | |
| 映射非特异性过氧化氢酶的选择性氧化 | Homann, D. | N/A | Mapping Selective Oxidations of Unspecific Peroxygenases | |
| 古DNA阐明了属Ctenomys的模式标本的身份和地理起源 | Maestri, R. | N/A | Ancient DNA Clarifies the Identity and Geographic Origin of the holotype of the genus Ctenomys | |
| 星形胶质细胞埃兹蛋白定义了小鼠对压力诱导的抑郁行为的恢复力 | Lin, S.-S. | N/A | Astrocyte ezrin defines resilience to stress-induced depressive behaviours in mice | |
| 食物-肠道轴：新鲜蔬菜叶际病毒群多样且丰富，并能传递至人类肠道病毒群。 | Park, J.-W. | N/A | The food-gut axis: the phyllosphere virome of fresh vegetables is diverse, abundant, and transmitted to the human gut virome | |
| 人类动脉血管的细胞和转录组图谱 | Zhao, Q. | N/A | A cell and transcriptome atlas of the human arterial vasculature | |
| Ki67通过调控染色体周边的核脂质积累，促进有丝分裂期间染色体的个体化。 | Hu, H.-T. | N/A | Ki67 regulates nuclear lipid accumulation at the chromosomal periphery to facilitate chromosome individualization during mitosis | |
| 缺氧和GCM1表达的丧失阻止了人类滋养层干细胞的分化及接触抑制 | Cinkornpumin, J. K. | N/A | Hypoxia and loss of GCM1 expression prevents differentiation and contact inhibition in human trophoblast stem cells | |
| Robinow综合征DVL1突变在果蝇疾病模型中破坏形态发生和附肢形成 | Akarsu, G. | N/A | Robinow Syndrome DVL1 mutations disrupt morphogenesis and appendage formation in a Drosophila disease model | |
| 神经内分泌通过果蝇血管微环境调控肠道再生 | Medina, A. | N/A | Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila. | |
| 急性饮食中蛋氨酸的限制突显了新皮质发育对代谢变化的敏感性。 | Saha, S. | N/A | Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations | |
| 一罐蠕虫：估算全球蚯蚓物种数量 | Decaens, T. | N/A | A can of worms: estimating the global number of earthworm species | |
| 开发树皮甲虫鉴定工具的进展 | Marais, G. C. | N/A | Progress in Developing a Bark Beetle Identification Tool | |
| 草食动物的普遍性在多样化的种植系统中并不能很好地预测产量。 | Croijmans, L. | N/A | Herbivore prevalence poorly predicts yield in diverse cropping systems | |
| 格陵兰睡鲨（Somniosus microcephalus）的基因组为极端长寿现象提供了新的见解。 | Sahm, A. | N/A | The Greenland shark (Somniosus microcephalus) genome provides insights into extremelongevity | |
| xCell 2.0：用于细胞类型比例估计的稳健算法，预测免疫检查点阻断反应 | Angel, A. | N/A | xCell 2.0: Robust Algorithm for cell type Proportion Estimation Predicts Response to Immune Checkpoint Blockade | |
| AlphaFold2 筛选自噬中LC3-LIR相互作用的短线性基序（SLiM） | Stuke, J. F. M. | N/A | AlphaFold2 SLiM screen for LC3-LIR interactions in autophagy | |
| 通过三维神经胶质重编程生成人类小清蛋白中间神经元 | Stamouli, C. A. | N/A | Generating human parvalbumin interneurons through 3D glia reprogramming | |
| 系统注射东莨菪碱增加了固定头部小鼠的时间预测变异性。 | Ujihara, Y. | N/A | Systemic injection of scopolamine increased the variability of temporal prediction in head-fixed mice. | |
| 单细胞基因组和表观基因组共分析揭示了乳腺癌中的硬连线与可塑性 | Wang, K. | N/A | Single cell genome and epigenome co-profiling reveals hardwiring and plasticity in breast cancer | |
| # BioRxiv 2024-09-09 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 一种基于反义寡核苷酸的策略，用于改善22q11.2缺失综合征中的认知功能障碍 | Thakur, P. | N/A | An antisense oligonucleotide-based strategy to ameliorate cognitive dysfunction in the 22q11.2 Deletion Syndrome | |
| 基于基因组距离的微生物群体结构快速揭示方法（GRUMPS）：一种无需参考的基因组数据清洗方法 | Abram, K. Z. | N/A | Genomic Distance-based Rapid Uncovering of Microbial Population Structures (GRUMPS): a reference free genomic data cleaning methodology | |
| BrainSuite BIDS App：用于MRI分析的容器化工作流程 | Kim, Y. | N/A | BrainSuite BIDS App: Containerized Workflows for MRI Analysis | |
| 分子动力学模拟揭示了序列背景在植物基于ELF3-PrD的温度感应机制中的作用 | Lindsay, R. J. | N/A | Molecular dynamics simulations illuminate the role of sequence context in the ELF3-PrD-based temperature sensing mechanism in plants | |
| 人类装配体揭示了CACNA1G基因变异在丘脑皮质通路中的后果 | Kim, J.-i. | N/A | Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway | |
| 多感官整合增强了Mauthner细胞的视听反应 | Otero Coronel, S. | N/A | Multisensory integration enhances audiovisual responses in the Mauthner cell | |
| 追踪单细胞癌症3D基因组的演变：癌症基因发现的图谱 | Liu, M. | N/A | Tracing the evolution of single-cell cancer 3D genomes: an atlas for cancer gene discovery | |
| 在健康老化过程中，大脑对语义知识的表征呈现出增强的泛化和特化现象。 | Margolles, P. | N/A | Enhanced generalization and specialization of brain representations of semantic knowledge in healthy aging | |
| 预期性脑活动依赖于预期刺激的感觉模式：单次试验分析的启示 | Hoxha, I. | N/A | Anticipatory brain activity depends on the sensory modality of the expected stimulus: insights from single-trial analyses | |
| 去势模型在性别差异研究中的适用性：代谢组学和转录组学分析的启示 | Jiang, J. | N/A | Applicability of Castration Model in Sex Difference Studies: Insights from Metabolome and Transcriptome Analyses | |
| 室管膜下区神经胶质生成调节脑缺血后胶质瘢痕处的细胞外基质 | Ardaya, M. | N/A | Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia | |
| MATES：一种基于深度学习的模型，用于单细胞中可移动元件的位点特异性定量 | Wang, R. | N/A | MATES: A Deep Learning-Based Model for Locus-specific Quantification of Transposable Elements in Single Cell | |
| 翻译启动或延伸抑制在病原体感染期间对秀丽隐杆线虫生存产生对比效应 | Ghosh, A. | N/A | Translation initiation or elongation inhibition triggers contrasting effects on Caenorhabditis elegans survival during pathogen infection | |
| NF1相关外周神经鞘瘤的基因组特征：来自约翰斯·霍普金斯大学NF1生物样本库的队列分析 | Banerjee, J. | N/A | Genomic features of NF1-associated peripheral nerve sheath tumors: a cohort analysis from the Johns Hopkins NF1 biospecimen repository | |
| 振幅压缩对注意神经语音追踪是有益还是阻碍？ | Orf, M. | N/A | Does amplitude compression help or hinder attentional neural speech tracking? | |
| CoCoPyE：用于学习和预测基因组质量指数的特征工程 | Birth, N. | N/A | CoCoPyE: feature engineering for learning and prediction of genome quality indices | |
| 通过靶向染色质编辑揭示的模拟表观遗传记忆 | Palacios, S. | N/A | Analog epigenetic memory revealed by targeted chromatin editing | |
| 开发一种实验协议，利用机器人技术和功能性磁共振成像研究手腕运动中力量和阻抗的神经控制 | Schmidt, K. | N/A | Development of an Experimental Protocol to Study the Neural Control of Force and Impedance in Wrist Movements with Robotics and fMRI | |
| 已撤回：研究音乐在年轻成年人中诱发平静的能力。 | Shepherd, D. | N/A | WITHDRAWN: Investigating the ability of music to induce calm in young adults. | |
| CTFFIND5 提供了对 TEM 样本质量、倾斜度和厚度的更深入的见解。 | Elferich, J. | N/A | CTFFIND5 provides improved insight into quality, tilt and thickness of TEM samples | |
| 化学诱导的衰老促使人类类小胶质细胞发生功能性变化 | Armanville, S. | N/A | Chemically induced senescence prompts functional changes in human microglia-like cells | |
| 体积电子显微镜揭示了死后人类前额叶皮层中的三维突触纳米结构 | Glausier, J. R. | N/A | Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex | |
| 调控网络结构对复杂性状遗传力和进化重要性的影响 | Stone, K. L. | N/A | The Importance of Regulatory Network Structure for Complex Trait Heritability and Evolution | |
| 顺铂对蛋白质磷酸化的重编程 | Qi, L. | N/A | Cisplatin reprogramming of protein phosphorylation | |
| 通过调节单个纳米颗粒蛋白质冠与小分子进行深度等离子体蛋白质组分析 | Ashkarran, A. A. | N/A | Deep Plasma Proteome Profiling by Modulating Single Nanoparticle Protein Corona with Small Molecules | |
| 长链非编码RNA Snhg3通过PPARγ信号通路加重肝脂肪变性 | Xie, X. | N/A | LncRNA Snhg3 Aggravates Hepatic Steatosis via PPARγ Signaling | |
| 通过系统评估化学数据的特性，为以数据为中心的虚拟药物筛选人工智能方法奠定基础 | Chong, A. | N/A | Establishing the foundations for a data-centric AI approach for virtual drug screening through a systematic assessment of the properties of chemical data | |
| 紫胸木蜂（Xylocopa violacea，林奈，1785年）的基因组序列：一种正在扩展分布范围的膜翅目物种。 | Nash, W. | N/A | The genome sequence of the Violet Carpenter Bee, Xylocopa violacea (Linnaeus, 1785): a hymenopteran species undergoing range expansion. | |
| 目标学习而非反向传播解释了哺乳动物新皮层中的学习过程 | Aceituno, P. V. | N/A | Target Learning rather than Backpropagation ExplainsLearning in the Mammalian Neocortex | |
| Atp1a2和Kcnj9是C57BL/6亚系中对羟考酮诱导的运动激活和戒断诱导的焦虑样行为敏感性的候选基因。 | Goldberg, L. R. | N/A | Atp1a2 and Kcnj9 are candidate genes underlying sensitivity to oxycodone-induced locomotor activation and withdrawal-induced anxiety-like behaviors in C57BL/6 substrains | |
| 环境大肠杆菌中的喹诺酮抗性基因qnr、aac(6')-Ib-cr、oqxAB和qepA：通过比较基因组学对其遗传背景的洞察 | Gomi, R. | N/A | Quinolone resistance genes qnr, aac(6')-Ib-cr, oqxAB, and qepA in environmental Escherichia coli: insights into their genetic contexts from comparative genomics | |
| 专家指导的蛋白质语言模型能够实现准确且极速的适应性预测 | Marquet, C. | N/A | Expert-guided protein Language Models enable accurate and blazingly fast fitness prediction | |
| 表面脂质影响线虫发育和物种特异性化学信号传导 | Kotowska, A. M. | N/A | Surface lipids influence developmental and species-specific chemical signalling in nematodes | |
| 细胞成像与化学结构跨域可以相互补充，用于在化学早期去风险中的大鼠急性口服毒性预测。 | Camilleri, F. | N/A | Cell Painting and chemical structure read-across can complement each other for rat acute oral toxicity prediction in chemical early de-risking | |
| CellSeg3D：用于光片显微镜的自监督3D细胞分割 | Achard, C. | N/A | CellSeg3D: self-supervised 3D cell segmentation for light-sheet microscopy | |
| 间接遗传效应增加了可供选择的可遗传变异，并且对于行为来说这种效应最大：一项元分析 | Santostefano, F. | N/A | Indirect genetic effects increase the heritable variation available to selection and are largest for behaviours: a meta-analysis | |
| 乐观和悲观的认知判断偏差调节斑马鱼的压力反应和癌症进展 | Espigares, F. | N/A | Optimistic and pessimistic cognitive judgement bias modulates the stress response and cancer progression in zebrafish | |
| 放大双耳间电平差异可增强双侧耳蜗植入者从掩蔽中的空间释放 | Richardson, B. N. | N/A | Magnified interaural level differences enhance spatial release from masking in bilateral cochlear implant users | |
| 表观遗传年龄模型在新一代甲基化阵列中的适用性 | Garma, L. D. | N/A | Applicability of epigenetic age models to next-generation methylation arrays | |
| 中央觅食者、猎物耗竭光环以及行为性生态位分隔如何促进消费者共存 | Rueffler, C. | N/A | Central place foragers, prey depletion halos, and how behavioral niche partitioning promotes consumer coexistence | |
| 在不进行额外训练或数据的情况下，提高逆折叠模型在蛋白质稳定性预测中的表现 | Dutton, O. | N/A | Improving Inverse Folding models at Protein Stability Prediction without additional Training or Data | |
| 一种改进的四环素诱导型裂殖酵母表达系统 | Lyu, X.-H. | N/A | An improved tetracycline-inducible expression system for fission yeast | |
| 在或外？利用高分辨率原子力显微镜追踪复杂DNA结构 | Holmes, E. P. | N/A | Under or Over? Tracing Complex DNA Structures with High-Resolution Atomic Force Microscopy | |
| 物种形成完成率对宏观进化多样化的影响有限 | Veron, P. | N/A | Speciation completion rates have limited impact on macroevolutionary diversification | |
| CLEC18A与硫酸化的糖胺聚糖相互作用，并调控肾透明细胞癌的进展。 | Jonsson, G. | N/A | CLEC18A interacts with sulfated GAGs and controls clear cell renal cell carcinoma progression | |
| 哈茨木霉T22通过系统信号诱导根瘤菌和类黄酮，以对抗豌豆中的铁缺乏症。 | Thapa, A. | N/A | Trichoderma afroharzianum T22 induces rhizobia and flavonoid through systemic signaling to combat Fe deficiency in garden pea | |
| 使用lr-kallisto进行长读长测序转录组定量 | Loving, R. K. | N/A | Long-read sequencing transcriptome quantification with lr-kallisto | |
| 奖励历史引导胡须体感皮层的焦点注意 | Ramamurthy, D. L. | N/A | Reward history guides focal attention in whisker somatosensory cortex | |
| Lphn1基因敲除抑制结直肠癌机制的研究 | wang, Y. | N/A | Research on the Mechanism of Lphn1 Knockout in Inhibiting Colorectal Cancer | |
| 对抗学习能够在大规模范围内实现单细胞RNA数据的跨物种无偏差全生物体对齐。 | Cooper, S. | N/A | Adversarial learning enables unbiased organism-wide cross-species alignment of single-cell RNA data at scale | |
| 尿液多组学揭示了透明细胞肾细胞癌的非侵入性诊断生物标志物 | Jonsson, G. | N/A | Urinary multi-omics reveal non-invasive diagnostic biomarkers in clear cell renal cell carcinoma | |
| 动态水凝胶交联强度控制着注射过程中的屈服特性和细胞活力 | Eckman, N. | N/A | Dynamic Hydrogel Crosslink Strength Controls Yielding Characteristics and Cell Viability During Injection | |
| 单胺氧化酶C（MAO C）的进化与功能分析：MAO基因家族的新成员 | Merello, G. | N/A | Evolutionary and Functional Analysis of Monoamine Oxidase C (MAO C): A Novel Member of the MAO Gene Family | |
| 内生吡咯喹啉醌增强香蕉生长及对镰刀菌萎蔫病的免疫力，促进植物-微生物共生关系 | Hung, S.-H. W. | N/A | Endophytic pyrroloquinoline quinone enhances banana growth and immunity against Fusarium wilt for plant-microbe mutualisms | |
| 深度逆向建模揭示了神经回路机制中的动态依赖不变性 | Gao, R. | N/A | Deep inverse modeling reveals dynamic-dependent invariances in neural circuit mechanisms | |
| BCL2L13 影响自噬和神经酰胺代谢，但不影响胶质母细胞瘤中的替莫唑胺耐药性 | Clark, C. | N/A | BCL2L13 Influences Autophagy and Ceramide Metabolism without Affecting Temozolomide Resistance in Glioblastoma | |
| BCV和（S）-HPMPA的新型衍生物比BCV更有效地抑制正痘病毒和人类腺病毒。 | Zhang, Y. | N/A | Novel derivatives of BCV and (S)-HPMPA inhibit orthopoxviruses and human adenoviruses more potently than BCV | |
| 添加留尼汪岛节肢动物名录 | Nibouche, S. | N/A | Additions to the list of arthropods of Reunion Island | |
| 特定纹状体神经元群的异常过度活跃通过高分辨率聚类揭示了不同的运动障碍行为 | Alcacer, C. | N/A | Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering | |
| 解码斑马鱼早期胚胎发育过程中细胞特异性转录异质性和可变剪接 | Lin, X. | N/A | Deciphering the Cell Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish | |
| 解读斑马鱼早期胚胎发育过程中细胞特异性转录异质性和可变剪接 | Lin, X. | N/A | Deciphering the Cell-Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish | |
| 肠道干细胞的增殖和分化依赖于锌指转录因子BCL11/Chronophage。 | Redhai, S. | N/A | Proliferation and differentiation of intestinal stem cells depends on the zinc finger transcription factor BCL11/Chronophage | |
| 杯状子叶2激活MIR319C转录并在拟南芥叶原基中促进细胞增殖 | Alanga, N. S. | N/A | CUP-SHAPED COTYLEDON2 activates MIR319C transcription and promotes cell proliferation in Arabidopsis leaf primordia | |
| 在单倍体-二倍体植物马钱子（Marchantia polymorpha subsp. ruderalis）中，选择效力在不同生活阶段有所差异。 | Shen, T. | N/A | Selection efficacy differs between lifestages in thehaploid-diploid Marchantia polymorpha subsp. ruderalis | |
| 模式工业产油微藻Nannochloropsis oceanica中碳浓缩机制的动态表观基因组景观 | Gong, Y. | N/A | Dynamic epigenomic landscape of carbon-concentrating mechanisms in the model industrial oleaginous microalga Nannochloropsis oceanica | |
| 一种结合基因组和外显子组测序的方法能够以无偏差、高质量且经济高效的方式捕获遗传变异。 | Boltz, T. A. | N/A | A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner | |
| 金黄色叙利亚仓鼠（Mesocricetus auratus）作为一种模型，用于解析与绵羊相关恶性卡他热的相关致病方面。 | Fabian, R. | N/A | The golden Syrian hamster (Mesocricetus auratus) as a model to decipher relevant pathogenic aspects of sheep-associated malignant catarrhal fever | |
| 甲基磺酰甲烷：一种针对胶质母细胞瘤多形性中涉及的鞘氨醇激酶1的潜在膳食补充剂 | Ahmad, F. | N/A | Methylsulfonylmethane: A Potential Dietary Supplement targeting sphingosine kinase 1 involved in Glioblastomamultiforme | |
| 巴基斯坦临床肺炎克雷伯菌中携带blaNDM-1、-5、-7碳青霉烯酶基因的质粒基因组特征分析 | Qamar, M. U. | N/A | Genomic characterization of plasmids harboring blaNDM-1,-5,-7 carbapenemase alleles in clinical Klebsiella pneumoniae in Pakistan | |
| 光化学过程驱动深海中溶解有机物的温度响应 | Hu, A. | N/A | Photochemical processes drive thermal responses of dissolved organic matter in the dark ocean | |
| 理解产生侧捏运动的大拇指肌肉小群：应用于神经损伤后抓握功能的手术修复 | Smith, C. D. | N/A | Toward an understanding of the small groups of thumb muscles that produce lateral pinch movement: application to surgical restoration of grasp following neurologic impairment | |
| MaskMol：用于活性悬崖的像素掩码知识引导分子图像预训练框架 | cheng, Z. | N/A | MaskMol: Knowledge-guided Molecular Image Pre-Training Framework for Activity Cliffs with Pixel Masking | |
| 利用RNA-seq解析羽扇豆（Lupinus angustifolius）种子发育过程中的转录编程 | WAINAINA, V. | N/A | Deciphering transcriptional programming during lupin (Lupinus angustifolius) seed development using RNA-seq | |
| 根据三维形态测量学见解，田鼠亚科啮齿动物（Rodentia）颅骨的演化：第一部分。腭蝶翼骨复合体的形态差异 | Voyta, L. L. | N/A | Evolution of the skull in arvicoline cricetids (Rodentia) according to 3D morphometric insights: Part 1. Morphological disparity of the palato-spheno-pterygoid complex | |
| 在发育过程中恢复短暂连接性可改善脆性X小鼠的功能障碍 | Dumontier, D. | N/A | Restoring transient connectivity during development improves dysfunctions in fragile X mice | |
| 高分辨率fMRI中的模糊波纹伪影：识别、成因及缓解方法 | Huber, L. | N/A | Fuzzy ripple artifact in high resolution fMRI: identification, cause, and mitigation | |
| 在创意讲故事过程中，创意生成与评估之间存在动态循环 | Liang, X. | N/A | Dynamic cycles between idea generation and evaluation during creative storytelling | |
| 功能性见解：全球野化对猫肠道微生物群的影响 | Aizpurua, O. | N/A | Functional insights into the effect of feralisation on the gut microbiota of cats worldwide | |
| 对全球范围内野化对猫肠道微生物群影响的功能性见解 | Aizpurua, O. | N/A | Functional insights into the effect of feralisation on the gut microbiota of cats worldwide | |
| 南非现存最大规模的蓝角马（Connochaetes taurinus taurinus）迁徙种群的遗传多样性与种群历史 | Szarmach, S. | N/A | Genetic diversity and demographic history of the largest remaining migratory population of blue wildebeest (Connochaetes taurinus taurinus) in southern Africa | |
| 南非现存最大规模的蓝角马（Connochaetes taurinus taurinus）迁徙种群的遗传多样性与种群历史 | Szarmach, S. | N/A | Genetic diversity and demographic history of the largest remaining migratory population of blue wildebeest (Connochaetes taurinus taurinus) in southern Africa | |
| 一种稳健的无监督聚类方法用于高维生物成像数据，揭示了共享的药物诱导形态特征 | Bao, S. C. | N/A | A robust unsupervised clustering approach for high-dimensional biological imaging data reveals shared drug-induced morphological signatures | |
| 水杨酸抑制细胞伸长并诱导液泡形态和pH值的变化。 | Mueller, J. | N/A | Salicylic Acid restricts cell elongation and induces changes of vacuolar morphology and pH | |
| 细胞骨架破坏对质膜受体动力学的对比效应：来自单分子分析的见解 | Rohr, L. | N/A | Contrasting Effects of Cytoskeleton Disruption on Plasma Membrane Receptor Dynamics: Insights from Single-Molecule Analyses | |
| 改变拟南芥的糖代谢会影响分泌物、免疫反应以及植物与微生物的相互作用 | Siffert, A. | N/A | Altered Arabidopsis thaliana sugar metabolism affects exudation, immune responses, and plant-microbe interactions | |
| 细胞几何结构、微管锚定及各向异性的动态不稳定性：横向皮质阵列组织的挑战与解决方案 | Tian, T. Y. Y. | N/A | Cell geometry, microtubule anchoring and anisotropic dynamic instability: challenges and solutions to transverse cortical array organization | |
| 跨物种相互作用组分析揭示了植物中一种保守的选择性自噬机制，用于蛋白质质量控制 | Hernandez, V. S. d. M. | N/A | Cross-species interactome analysis uncovers a conserved selective autophagy mechanism for protein quality control in plants | |
| 停止速度作为状态而非特质：探究多轮停止信号任务中动物间停止速度的差异 | ter Horst, J. | N/A | Stopping Speed as State, Not Trait: Exploring Within-Animal Varying Stopping Speeds in a Multi-Session Stop-Signal Task | |
| 视觉逃避习惯化中个体差异的神经回路 | Liu, X. | N/A | Neural Circuit Underlying Individual differences in Visual Escape Habituation | |
| HHIP在表皮伤口愈合中的动态作用揭示了COPD易感性的潜在机制 | Deritei, D. | N/A | HHIP's Dynamic Role in Epithelial Wound Healing Reveals a Potential Mechanism of COPD Susceptibility | |
| 马拉维分离株中T. b. rhodesiense血清抗性相关基因的遗传多样性 | Nambala, P. | N/A | GENETIC DIVERSITY OF T. B. RHODESIENSE SERUM RESISTANCE ASSOCIATED GENE IN MALAWIAN ISOLATES | |
| 等位基因特异性表达在肿瘤发生过程中被选择，源于表观遗传变化，并与预后相关。 | Palou-Marquez, G. | N/A | Allele-specific expression is selected in tumorigenesis, results from epigenetic changes and has prognostic relevance | |
| 15基因预后特征，其中TFAP2B在卵巢癌铂耐药中发挥作用 | Hu, Y. | N/A | A 15-Gene prognostic signature with TFAP2B functioning in Platinum Resistance of Ovarian Carcinoma | |
| 进化与生命在多个粒度上的分支紧密相连。 | Douglas, J. | N/A | Evolution is coupled with branching across many granularities of life | |
| 一种基于胍的冠状病毒复制抑制剂，靶向nsp15内切核糖核酸酶，结合了直接的抗病毒效果与微妙的干扰素增强作用。 | Van Loy, B. | N/A | A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and combines a direct antiviral effect with subtle boosting of interferon | |
| CRISPR-CLEAR：通过平铺碱基编辑的等位基因读出实现调控元件的核苷酸分辨率映射 | Becerra, B. | N/A | CRISPR-CLEAR: Nucleotide-Resolution Mapping of Regulatory Elements via Allelic Readout of Tiled Base Editing | |
| 与AK2A的相互作用将AIFM1与细胞能量代谢联系起来 | Rothemann, R. A. | N/A | Interaction with AK2A links AIFM1 to cellular energy metabolism | |
| 选择性氘化RNA:RNA复合物用于结构分析的小角散射 | Munsayac, A. | N/A | Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering | |
| 磷脂酰肌醇聚焦的CRISPR筛选识别出胰腺导管腺癌（PDAC）和急性髓系白血病（AML）细胞中的新型遗传脆弱性 | Lee, D. K. | N/A | Phosphoinositide-focused CRISPR screen identifies novel genetic vulnerabilities in PDAC and AML cells | |
| 长期热应激增强蚊子对病毒感染的耐受性 | Perdomo, H. D. | N/A | Prolonged thermal stress enhances mosquito tolerance to viral infection | |
| Kinbiont：从时间序列到微生物系统中的生态和进化响应 | Angaroni, F. | N/A | Kinbiont: From time series to ecological and evolutionary responses in microbial systems | |
| 铜绿假单胞菌在呼吸道感染期间面临一种适应性权衡，即在黏膜定植与抗生素耐受性之间做出选择。 | Meirelles, L. A. | N/A | Pseudomonas aeruginosa faces a fitness trade-off between mucosal colonization and antibiotic tolerance during airway infections | |
| 通过拓扑约束分子生成模型发现针对COVID-19的新型喹啉类木瓜蛋白酶样蛋白酶抑制剂 | Shang, J. | N/A | Discovery of novel quinoline papain-like protease inhibitors for COVID-19 through topology constrained molecular generative model | |
| 通过蛋白质组学检测ESKAPE病原体的抗生素抗性并同时鉴定其物种 | Blumenscheit, C. | N/A | Antibiotic resistance detection and concomitant species identification of ESKAPE pathogens by proteomics | |
| 利用PREDAC模型模拟季节性流感病毒的抗原进化，以在2025年季节中选择疫苗株 | Peng, Y. | N/A | Modeling the antigenic evolution of seasonal influenza viruses with PREDAC for vaccine strain selection in the season of 2025 | |
| 利用CRISPR-Cas13d在诱导性敲降系统中研究果蝇生殖颗粒mRNA | Gauhar, Z. A. | N/A | Leveraging CRISPR-Cas13d in an inducible knockdown system to interrogate Drosophila germ granule mRNAs | |
| SIRT6缺失通过促进衰老和SASP状态导致小鼠椎间盘退变 | Ramteke, P. | N/A | SIRT6 loss causes intervertebral disc degeneration in mice by promoting senescence and SASP status | |
| 拟南芥tRNA氨基酸化作用的景观 | Ceriotti, L. F. | N/A | The landscape of Arabidopsis tRNA aminoacylation | |
| 高质量的肽段证据用于注释非规范开放阅读框为人类蛋白质 | Deutsch, E. W. | N/A | High-quality peptide evidence for annotating non-canonical open reading frames as human proteins | |
| 高吞吐量酶促DNA甲基化测序的经济高效解决方案 | Longtin, A. | N/A | Cost-effective solutions for high-throughput enzymatic DNA methylation sequencing | |
| 转录因子网络对血液细胞表型的遗传性具有不成比例的富集作用 | Martin-Rufino, J. D. | N/A | Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes | |
| 将新开发的SNP条形码面板与微卫星进行比较，以探索秘鲁亚马逊地区疟疾病原体的群体遗传学 | Cabrera-Sosa, L. | N/A | Comparing newly developed SNP barcode panels with microsatellites to explore population genetics of malaria parasites in the Peruvian Amazon | |
| 一种致病突变如何从单体到完全组装状态损害Hsp60的功能动态 | Torielli, L. | N/A | How a pathogenic mutation impairs Hsp60 functional dynamics from monomeric to fully assembled states | |
| 一种与能量平衡相关的次级β-羟基丁酸代谢途径 | Moya-Garzon, M. D. | N/A | A secondary β-hydroxybutyrate metabolic pathway linked to energy balance | |
| 通过FeII/2-氧代戊二酸依赖的双加氧酶进行非耦合琥珀酸生产的比较分析 | Das, S. | N/A | Comparative analysis of uncoupled succinate production by the FeII/2-oxoglutarate-dependent dioxygenases | |
| 尿酸在人类URAT1中的转运机制及促尿酸排泄药物的抑制作用 | Guo, W. | N/A | Mechanisms of urate transport and uricosuric drugs inhibition in human URAT1 | |
| 人类心脏类器官的成熟对于疾病建模和药物发现是必要的。 | Pocock, M. | N/A | Maturation of human cardiac organoids are required for disease modelling and drug discovery | |
| 结核分枝杆菌拓扑异构酶IA在C端缺失的情况下会遭受能量上的困扰 | Balthrop, D. | N/A | Mycobacterial Topoisomerase IA Energetically Suffers From C-terminal Deletions | |
| CRISPRoff表观遗传编辑：在人类细胞中实现可编程基因沉默，无需DNA断裂 | Pattali, R. K. | N/A | CRISPRoff epigenetic editing for programmable gene silencing in human cells without DNA breaks | |
| 昆虫宿主中功能性微生物植酸酶的生物制造。 | Retief, C. | N/A | Biomanufacturing of a functional microbial phytase in an insect host. | |
| 使用中尺度透析系统在PURE中实现长期蛋白质合成 | Julia, L. R. | N/A | Long-term protein synthesis with PURE in a mesoscale dialysis system | |
| 跨物种全脑映射揭示了由伏隔核深部脑刺激所激活的保守且协调的神经网络 | Feng, A. | N/A | Cross-species brain-wide mapping reveals a conserved and coordinated network engaged by NAc DBS | |
| 通过双向循环门控建模大脑中的注意力和绑定机制 | Salehinajafabadi, S. | N/A | Modeling Attention and Binding in the Brain through Bidirectional Recurrent Gating | |
| 光感受器退化对功能性视网膜神经节细胞类型产生异质性影响 | Dyszkant, N. | N/A | Photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types | |
| 毛圆蛛（Uloborus diversus）大脑的三维免疫荧光图谱。 | Artiushin, G. | N/A | A three-dimensional immunofluorescence atlas of the brain of the hackled-orb weaver spider, Uloborus diversus. | |
| 在巨细胞核中存在α-突触核蛋白聚集的前驱性突触核病模型中，运动迟缓和姿势不稳定的症状。 | Theologidis, V. | N/A | Bradykinesia and postural instability in a model of prodromal Synucleinopathy with alpha-Synuclein aggregation in the gigantocellular nuclei. | |
| 非麻痹手臂的使用反映了慢性中风患者的一种习惯性行为。 | Sporn, S. | N/A | Use of the non-paretic arm reflects a habitual behaviour in chronic stroke | |
| 健康供体与急性移植物抗宿主病患者T细胞反应的比较评估：定制免疫监测平台 | Mendiratta, M. | N/A | A Comparative assessment of T-Cell response of Healthy donors and Acute Graft-versus-Host-Disease Patients: Customizing immune monitoring platform | |
| 从家养和野生动物中分离出的Trueperella pyogenes的基因组和代谢特征分析 | Magossi, G. | N/A | Genomic and metabolic characterization of Trueperella pyogenes isolated from domestic and wild animals | |
| 冷冻电镜揭示了RNA聚合酶I在无碱基DNA损伤处暂停和停滞的顺序机制 | Santos-Aledo, A. | N/A | Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions | |
| 膜结合的钙粘蛋白底物揭示了粘着连接处的肌动蛋白结构 | Ghosh, S. | N/A | Membrane-tethered cadherin substrates reveal actin architecture at adherens junctions | |
| 人类肺部神经内分泌细胞对屋尘螨提取物产生反应，通过PAR-1依赖性途径释放CGRP。 | Mann-Nuttel, R. | N/A | Human pulmonary neuroendocrine cells respond to House dust mite extract with PAR-1 dependent release of CGRP | |
| Rho-ROCK释放被隔离的claudin，以促进新紧密连接的快速形成 | Cho, Y. | N/A | Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation | |
| 癌症中新型潘尼克斯1异构体表达增加 | O'Donnell, B. L. | N/A | Novel Pannexin 1 isoform is increased in cancer | |
| 中期形成初期的早期事件稳定了新生成的双极纺锤体 | Sim, S. | N/A | Early events in midzone formation stabilize nascent bipolar spindles | |
| 平衡肌动蛋白网络竞争中的有限资源 | Guerin, C. | N/A | Balancing limited resources in actin networks competition | |
| 电子冷冻断层扫描揭示了纤毛内连接的结构 | Li, S. | N/A | The Structure of Cilium Inner Junctions Revealed by Electron Cryo-tomography | |
| Maspin/SerpinB5是一种细胞骨架结合蛋白，能够调控上皮细胞的形态。 | da Silva, L. | N/A | Maspin/SerpinB5 is a cytoskeleton-binding protein that regulates epithelial cell shape | |
| 间歇性缺氧通过依赖活性氧的机制增加H3K27乙酰化，这一过程受H3S28磷酸化的调控。 | Nanduri, J. | N/A | Reactive Oxygen species dependent increase in H3K27 acetylation by intermittent hypoxia is regulated by H3S28 phosphorylation | |
| 哺乳动物肺纤维化中的神经-成纤维细胞轴 | Ishikawa, G. | N/A | A Nerve-Fibroblast Axis in Mammalian Lung Fibrosis | |
| 促性腺激素细胞具有双重起源，其中大多数在微青春期期间源自垂体干细胞。 | Sheridan, D. | N/A | Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty. | |
| 引入的鳟鱼阻碍了本地鱼类在极端洪水干扰后的恢复 | Lennox, R. S. | N/A | Introduced trout hinder the recovery of native fish following an extreme flood disturbance | |
| 学龄前音乐性通过与节奏性相关的基因与学龄期沟通能力相关联。 | de Hoyos, L. | N/A | Preschool musicality is associated with school-age communication abilities through genes related to rhythmicity | |
| VCP（一种重要的解旋酶）与去泛素酶之间不同的耦合模式 | Vostal, L. E. | N/A | Distinct modes of coupling between VCP, an essential unfoldase, and deubiquitinases | |
| 在搅拌罐生物反应器中，胰腺β细胞的外泌体三步可扩展生产促进了细胞成熟及具有保留免疫调节特性的外泌体释放。 | De Beaurepaire, L. | N/A | Three-step scalable production of extracellular vesicles from pancreatic beta cells in stirred tank bioreactors promotes cell maturation and release of ectosomes with preserved immunomodulatory properties | |
| BFVD - 一个预测病毒蛋白质结构的大型数据库 | Steinegger, M. | N/A | BFVD - a large repository of predicted viral protein structures | |
| 利用CellMATE解锁单细胞与空间联合分析的跨模态互动 | Jingping, Y. | N/A | Unlocking cross-modal interplay of single-cell and spatial joint profiling with CellMATE | |
| 估计2022/24年高致病性禽流感病毒传入美国各商业禽群的适当接触率和时间 | Ssematimba, A. | N/A | Estimating adequate contact rates and time of Highly Pathogenic Avian Influenza virus introduction into individual United States commercial poultry flocks during the 2022/24 epizootic | |
| 全血生理应激引起的可逆转录组年龄变化 | Bhak, J. | N/A | Reversible Transcriptomic Age Shifts from Physiological Stress in Whole Blood | |
| 肌钙蛋白-C突变谱中的钙结合亲和力：自由能计算、协同进化建模与机器学习 | Pooja, | N/A | Calcium Binding Affinity in the Mutational Landscape of Troponin-C: Free Energy Calculation, Co-evolution modeling and Machine Learning | |
| 三阴性乳腺癌患者来源的异种移植模型中，线粒体的三维分析揭示了化疗治疗后线粒体网络的重塑 | Berner, M. J. | N/A | Three-dimensional analysis of mitochondria in a patient-derived xenograft model of triple negative breast cancer reveals mitochondrial network remodeling following chemotherapy treatments | |
| 通过ZenoTOF技术进行的定量特异性糖蛋白质组学揭示了用于乳腺癌诊断的糖基特征 | Yang, Y. | N/A | Quantitative site-specific glycoproteomics by ZenoTOF reveals glyco-signatures for breast cancer diagnosis | |
| 细胞外囊泡通过将ATP合成转运至伪足并激活整合素粘附复合物，调控淋巴管平滑肌瘤细胞的亚稳态表型。 | Kalvala, A. K. | N/A | Extracellular vesicles regulate metastable phenotypes of lymphangioleiomyomatosis cells via shuttling ATP synthesis to pseudopodia and activation of integrin adhesion complexes. | |
| 在神经纤维瘤病1型中，正常组织中的与癌症无关的第二次体细胞NF1突变 | Oliver, T. R. W. | N/A | Cancer-independent, second somatic NF1 mutation of normal tissues in neurofibromatosis type 1 | |
| NR2F2在早期脂肪细胞干细胞样细胞中的再激活可挽救脂肪细胞线粒体氧化 | Das, S. | N/A | NR2F2 Reactivation in Early-life Adipocyte Stem-like Cells Rescues Adipocyte Mitochondrial Oxidation | |
| HYCCIN2通过招募SH3P2-DRP1A驱动拟南芥胚胎细胞板形成中的膜管化 | Hsu, Y.-w. | N/A | Recruitment of SH3P2-DRP1A by HYCCIN2 Drives Membrane Tubulation in Arabidopsis Embryonic Cell Plate Formation | |
| 雌激素受体α介导的PRICKLE1抑制作用破坏了REST的稳定性，并促进了子宫肌瘤的发病机制。 | McWilliams, M. M. | N/A | Estrogen receptor alpha mediated repression of PRICKLE1 destabilizes REST and promotes uterine fibroid pathogenesis | |
| Osterix通过靶向连接蛋白43促进骨细胞间的通讯 | wu, z. | N/A | Osterix Facilitates Osteocytic Communication by Targeting Connexin43 | |
| SAF-A SAP结构域在X染色体失活、转录、剪接和细胞增殖中的作用 | Sharp, J. A. | N/A | Role of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation | |
| 突触前神经元是线粒体自噬的驿站，能防止轴突退化。 | Lam, W. K. | N/A | Presynapses are mitophagy pit stops that prevent axon degeneration | |
| 力量变异性可能是半球中风幸存者运动障碍的潜在生物标志物。 | Shi, F. | N/A | Force variability is a potential biomarker of motor impairment in hemispheric stroke survivors | |
| 帕金森病患者中有一小部分人的骨骼肌出现了线粒体复合物I缺陷。 | Kverneng, S. U. | N/A | Mitochondrial complex I deficiency occurs in skeletal muscle of a subgroup of individuals with Parkinson's disease | |
| # BioRxiv 2024-09-08 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 局部矿物稳态的变化促进了良性和恶性睾丸微钙化的形成。 | Boisen, I. M. | N/A | Changes in local mineral homeostasis facilitate the formation of benign and malignant testicular microcalcifications | |
| 在概率奖励学习过程中，通过小鼠内侧前额叶皮层进行的变化点估计 | Murphy, C. E. | N/A | Change point estimation by the mouse medial frontal cortex during probabilistic reward learning | |
| 基于大肠杆菌的细胞无细胞系统中的代谢扰动揭示了转录与翻译之间的权衡关系 | Kapasiawala, M. | N/A | Metabolic perturbations to an E. coli-based cell-free system reveal a trade-off between transcription and translation | |
| 贝阿特丽斯：使用深度变分推断从摘要数据进行贝叶斯精细定位 | Ghosal, S. | N/A | BEATRICE: Bayesian Fine-mapping from Summary Datausing Deep Variational Inference | |
| 如果……会怎样？小脑皮质颗粒层的计算解剖学 | Gilbert, M. | N/A | What if...? Computational anatomy in the granular layer of the cerebellar cortex | |
| 对费氏弧菌中环二鸟苷酸调节蛋白的功能分析 | Isenberg, R. Y. | N/A | Functional analysis of cyclic diguanylate-modulating proteins in Vibrio fischeri | |
| 大脑在多步骤预测过程中，会分层次地表征过去和未来。 | Tarder-Stoll, H. | N/A | The brain hierarchically represents the past and future during multistep anticipation | |
| 体质人类学研究中主成分分析（PCA）的偏见需要重新评估进化见解 | Mohseni, N. | N/A | Biases of Principal Component Analysis (PCA) in Physical Anthropology Studies Require a Reevaluation of Evolutionary Insights | |
| 早期生活逆境对压力反应性的性别特异性和发育影响可通过出生后敲低5-HT1A自身受体得到挽救 | Dixon, R. | N/A | Sex-specific and Developmental Effects of Early Life Adversity on Stress Reactivity are Rescued by Postnatal Knockdown of 5-HT1A Autoreceptors | |
| APP调控因子RHBDL4的丢失在阿尔茨海默病小鼠模型中保护了记忆。 | Penalva, Y. C. M. | N/A | Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model. | |
| 膜泡可以通过船蛆的可培养胞内共生体Teredinibacter turnerae促进纤维素降解。 | Gasser, M. T. | N/A | Membrane vesicles can contribute to cellulose degradation by Teredinibacter turnerae, a cultivable intracellular endosymbiont of shipworms | |
| 虚拟现实课堂中的选择性注意与听觉干扰敏感性：AD(H)D成人与非AD(H)D成人的比较 | Levy, O. | N/A | Selective attention and sensitivity to auditory disturbances in a virtually-real Classroom: Comparison of adults with and without AD(H)D | |
| 藤蔓衰退病对西瓜果实氨基酸代谢的影响 | Santo, H. | N/A | Influence of vine decline disease on the amino acid metabolism of watermelon fruit | |
| 先前未测量的遗传多样性解释了基于k-mer的112种植物物种元分析中莱文廷悖论的部分内容 | Roberts, M. D. | N/A | Previously unmeasured genetic diversity explains part of Lewontin's paradox in a k-mer-based meta-analysis of 112 plant species | |
| 发育中的高级皮层中，相关自发性活动建立了多感官整合 | Dwulet, J. M. | N/A | Correlated spontaneous activity sets up multi-sensory integration in the developing higher-order cortex | |
| 组胺干扰了小鼠的早期视觉处理 | Tripodi, M. | N/A | Histamine interferes with the early visual processing in mice | |
| 大型齿鲸种内体型变异的总结 | McClure, J. | N/A | A summary of intraspecific size variation for large odontocetes | |
| 结构蛋白质组学揭示了孕酮受体的顺序启动机制 | Mann, M. D. | N/A | Structural proteomics defines a sequential priming mechanism for the progesterone receptor | |
| 结构稳定性决定了互利共生模型生态系统中的进化稳定性 | Lurgi, M. | N/A | Structural stability determines evolutionary stability in mutualistic model ecosystems | |
| 连接牙冠：分析现代人类后臼齿的形态协变 | Simkova, P. G. | N/A | Connecting crowns: Analyzing morphological covariation in the modern human postcanine dentition | |
| 每个速率类别独立碱基组成的改进似然性系统发育估计：5rf模型 | Waddell, P. J. | N/A | An independent base composition of each rate class for improved likelihood-based phylogeny estimation: The 5rf model | |
| 穴样蛋白-1和机械应力调控具有促转移作用的小型细胞外囊泡亚群的释放 | Saquel, C. | N/A | Caveolin-1 and mechanical stress control the release of a pro-metastatic subpopulation of small extracellular vesicles | |
| 单核多组学揭示了皮克氏病和阿尔茨海默病中共享及独特的通路 | Shi, Z. | N/A | Single-nucleus multi-omics identifies shared and distinct pathways in Pick's and Alzheimer's disease | |
| 在小鼠生命全程中，对少突胶质细胞组织和少突胶质细胞生成的全脑图谱分析 | Xu, Y. K. T. | N/A | Brain-wide mapping of oligodendrocyte organization and oligodendrogenesis across the murine lifespan | |
| 在癫痫和智力障碍的人脑类器官模型中模拟皮层与海马网络功能障碍 | McCrimmon, C. M. | N/A | Modeling Cortical Versus Hippocampal Network Dysfunction in a Human Brain Assembloid Model of Epilepsy and Intellectual Disability | |
| 内吞素A1促进GABA能突触后机制的组织，以维持兴奋-抑制平衡 | Chen, X. | N/A | Endophilin A1 facilitates organization of the GABAergic postsynaptic machinery to maintain excitation-inhibition balance | |
| 一种依赖于多巴胺的机制，用于奖励诱导的恐惧记忆的修改 | Kong, M.-S. | N/A | A dopamine-dependent mechanism for reward-induced modification of fear memories | |
| 典型的突触和神经元特性的发育可以在没有小胶质细胞的情况下进行。 | O'Keeffe, M. | N/A | Typical development of synaptic and neuronal properties can proceed without microglia | |
| 从Cercis canadensis和Chamaecrista fasciculata基因组推断出的豆科基因组结构和历史 | Lee, H.-o. | N/A | Legume genome structures and histories inferred from Cercis canadensis and Chamaecrista fasciculata genomes | |
| 在100 keV能量下通过单颗粒冷冻电镜确定亚3 Å分辨率的蛋白质结构 | Karia, D. | N/A | Sub-3 A resolution protein structure determination by single-particle cryo-EM at 100 keV | |
| 未管理蜜蜂群落（Apis mellifera carnica）在森林环境中的蜂群活动率和活动时间 | Rutschmann, B. | N/A | Swarming rate and timing of unmanaged honeybee colonies (Apis mellifera carnica) in a forest environment | |
| 按蚊属物种复合体内味觉受体的分子进化 | Popkin-Hall, Z. R. | N/A | Molecular Evolution of Gustatory Receptors in the Anopheles gambiae Species Complex | |
| detectEVE：在基因组数据中快速、灵敏且精确地检测内源性病毒元素 | Brait, N. | N/A | detectEVE: fast, sensitive and precise detection of endogenous viral elements in genomic data | |
| NetMedPy：一个用于大规模网络医学筛选的Python包 | Aldana, A. | N/A | NetMedPy: A Python package for Large-Scale Network Medicine Screening | |
| 质子结合的变构调节赋予囊泡谷氨酸转运蛋白氯离子活化和谷氨酸选择性 | Borghans, B. | N/A | Allosteric modulation of proton binding confers Cl- activation and glutamate selectivity to vesicular glutamate transporters | |
| TCV的衣壳蛋白通过泛素化和自噬途径抑制RNA降解，从而促进病毒感染。 | Wu, K. | N/A | Coat protein of TCV suppresses RNA decay via ubiquitination and autophagy pathways to facilitate viral infection | |
| 全面表征BTK抑制剂的特异性、效力和生物效应：对共价和非共价机制特征的深入见解 | Darragh, A. C. | N/A | Comprehensive Characterization of BTK Inhibitor Specificity, Potency, and Biological Effects: Insights into Covalent and Non-covalent Mechanistic Signatures | |
| 基因组组成预测多倍体蝾螈对环境变化的生理反应 | Burger, I. | N/A | Genome composition predicts physiological response to environmental change in polyploid salamanders | |
| 叶绿体中磷脂酰肌醇（PPIs）的存在与功能的最新证据 | Sedaghatmehr, M. | N/A | New evidence for the presence and function of phosphoinositides (PPIs) in the chloroplast | |
| 特定纹状体神经元群的异常过度活跃通过高分辨率聚类揭示了不同的运动障碍行为 | Alcacer, C. | N/A | Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering | |
| 使用潜在类线性混合模型改进了间歇性获取两瓶选择大鼠模型中酒精摄入组的分类 | Angeles-Valdez, D. | N/A | Improved classification of alcohol intake groups in the Intermittent-Access Two-Bottle choice rat model using a latent class linear mixed model | |
| 特定特征的区分归一化改进了深度感知中自然图像的编码 | Ni, L. | N/A | Feature-specific divisive normalization improves natural image encoding for depth perception | |
| 通过表观遗传调控与免疫检查点抑制的联合作用增强HBV特异性T细胞反应 | Urbanek-Quaing, M. | N/A | Enhancing HBV-specific T cell responses through a combination of epigenetic modulation and immune checkpoint inhibition | |
| 野生动物的供给选择使宿主中不完全免疫的病原体毒性更高。 | Walsman, J. C. | N/A | Wildlife provisioning selects for higher pathogen virulence in hosts with incomplete immunity | |
| 杀伤性病毒感染对野生酿酒酵母的适应性影响 | Unni, R. | N/A | Fitness effects of killer virus infection on wild Saccharomyces paradoxus | |
| 利用单粒近红外光谱技术和基因组选择进行表型组选择，以改进玉米育种 | Prado Graciano, R. | N/A | Integrating Phenomic Selection Using Single-Kernel Near-Infrared Spectroscopy and Genomic Selection for Corn Breeding Improvement | |
| 探索破裂的人类股四头肌肌腱在单细胞分辨率下的细胞变化 | Mimpen, J. Y. | N/A | Exploring cellular changes in ruptured human quadriceps tendons at single-cell resolution | |
| 模块化光稳定荧光DNA块剖析病原体突变驱动蛋白对集体运输的影响 | Kita, T. | N/A | Modular photostable fluorescent DNA blocks dissect the effects of pathogenic mutant kinesin on collective transport | |
| mRNA密码子序列的深度生成优化，以提高蛋白质产量和治疗效果 | Li, Y. | N/A | Deep Generative Optimization of mRNA Codon Sequences for Enhanced Protein Production and Therapeutic Efficacy | |
| 在蛋白质约束模型中整合混杂酶活性，揭示了地下代谢在代谢表型稳健性中的作用 | de Moura Ferreira, M. A. | N/A | Integrating promiscuous enzyme activities in protein-constrained models pinpoints the role of underground metabolism in robustness of metabolic phenotypes | |
| 二光子驱动的虾青素功能化橙色类胡萝卜素蛋白光保护机制 | Nizinski, S. | N/A | Two-photon driven photoprotection mechanism in echinenone-functionalized Orange Carotenoid Protein | |
| 葡萄糖限制对癌症细胞收缩性的影响：U-87胶质瘤中的阈值反应 | Kong, A. | N/A | The effect of glucose restriction on cancer cell contractility: A threshold response in U-87 glioma | |
| 利用非扩散性邻近标记系统在活细胞和生物体内鉴定目标蛋白质 | Sun, Y. | N/A | Target protein identification in live cells and organisms with a non-diffusive proximity tagging system | |
| InCO的移码突变可能导致日本牵牛花的早花现象，并可能促成了其向北扩张。 | Katsuyama, H. | N/A | Frame-shift mutation of InCO might cause early flowering of Japanese morning glory and might have contributed to northward expansion | |
| 解决珊瑚微生境和礁石生态位中Symbiodiniaceae多样性问题 | Million, W. | N/A | Resolving Symbiodiniaceae diversity across coral microhabitats and reef niches | |
| 成对C型凝集素受体介导秀丽隐杆线虫对不同卵菌病原体的特异性识别。 | Liu, K. | N/A | Paired C-type lectin receptors mediate specific recognition of divergent oomycete pathogens in C. elegans. | |
| 在大量开花期间，地中海果园中管理的熊蜂溢出对生态系统造成了轻微的短期影响。 | Nachtom Catalan, N. | N/A | Spillover of managed bumble bees from Mediterranean orchards during mass flowering causes minor short-term ecological impacts | |
| 通过祖先序列重建研究酶的低温适应性 | Cui, S. | N/A | Insights into the low-temperature adaptation of an enzyme as studied through ancestral sequence reconstruction | |
| DupLoss-2：在基因重复和丢失条件下改进的系统基因组物种树推断 | Parsons, R. | N/A | DupLoss-2: Improved Phylogenomic Species Tree Inference under Gene Duplication and Loss | |
| 鼠标脑提取器：利用全局位置编码和SwinUNETR进行鼠标MRI的脑部分割 | Kim, Y. | N/A | Mouse Brain Extractor: Brain segmentation of mouse MRI using global positional encoding and SwinUNETR | |
| 学生自我调节会调节皮层兴奋性和皮层唤醒的标志物。 | Weijs, M. L. | N/A | Pupil self-regulation modulates markers of cortical excitability and cortical arousal | |
| 电极流形上睡眠慢振荡出现的预测建模：迈向个性化闭环脑刺激 | Alipour, M. | N/A | Predictive Modeling of Sleep Slow Oscillation Emergence on the electrode manifold: Toward Personalized Closed-Loop Brain Stimulation | |
| 一种用于功能性免疫细胞疗法微尺度生产的数字微流控平台 | Little, S. R. | N/A | A Digital Microfluidic Platform for the Microscale Production of Functional Immune Cell Therapies | |
| 一种用于在多重图像中分割细胞和细胞核的新型通道不变架构，采用InstanSeg技术。 | Goldsborough, T. | N/A | A novel channel invariant architecture for the segmentation of cells and nuclei in multiplexed images using InstanSeg | |
| 作物育种中基因组预测的集成方法预测性能的改进 | Tomura, S. | N/A | Improvements in Prediction Performance of Ensemble Approaches for Genomic Prediction in Crop Breeding | |
| 细菌细胞壁的非线性应力软化特性赋予了细胞形状的稳态维持能力。 | Bardetti, P. | N/A | Non-linear stress-softening of the bacterial cell wall confers cell shape homeostasis | |
| 细菌转录抑制因子NrdR - 一种灵活的多因素核苷酸传感器 | Rozman Grinberg, I. | N/A | Bacterial transcriptional repressor NrdR - a flexiblemultifactorial nucleotide sensor | |
| 类似自然语言处理的深度学习辅助在多种细菌中识别和验证硫代磺酸酯耐受性集群 | Myers, B. K. | N/A | Natural Language Processing-like Deep Learning Aided in Identification and Validation of Thiosulfinate Tolerance Clusters in Diverse Bacteria | |
| MYO5B缺陷引起的细胞代谢途径改变和上皮细胞成熟过程可以通过LPAR5激活部分逆转。 | Momoh, M. | N/A | Altered cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation | |
| 刺激重复在初级视觉皮层中引发了一个两阶段的学习过程。 | Cui, L. | N/A | Stimulus repetition induces a two-stage learning process in primary visual cortex | |
| DAR-901和BCG诱导的对抗鸟分枝杆菌的免疫 | Abate, G. | N/A | Immunity against Mycobacterium avium induced by DAR-901 and BCG | |
| 在原核腺苷酸激酶的热适应过程中，灵活性的变化而非紧密性的变化是其基础。 | Kontopoulos, D. - G. | N/A | Changes in flexibility but not in compactness underlie the thermal adaptation of prokaryotic adenylate kinases | |
| 作为治疗囊性纤维化的方法，子宫内全身基因编辑 | Ricciardi, A. S. | N/A | Systemic in utero gene editing as a treatment for cystic fibrosis | |
| NiCo通过微环境协变分析识别细胞状态调控的外在驱动因素 | Agrawal, A. | N/A | NiCo Identifies Extrinsic Drivers of Cell State Modulation by Niche Covariation Analysis | |
| 一种高度活跃的细菌肌动蛋白驱动了另一种对螺旋体游泳运动能力至关重要的同工型的聚合。 | Takahashi, D. | N/A | A highly active bacterial actin actuates the polymerization of another isoform essential for swimming motility of Spiroplasma | |
| 湿度作为昆虫系统昼夜节律同步的时间信号 | Chen, S.-C. | N/A | Humidity as a zeitgeber for circadian entrainment of insect systems | |
| 通过药代动力学模型测量心脏中活体和离体状态下的细胞膜和线粒体膜电位 | Waters, E. C. | N/A | Sarcolemmal and mitochondrial membrane potentials measured ex vivo and in vivo in the heart by pharmacokinetic modelling of sestamibi | |
| 兴奋性氨基酸转运蛋白3底物识别的结构基础 | Qiu, B. | N/A | Structural basis of the excitatory amino acid transporter 3 substrate recognition | |
| 通过时间分辨小角X射线散射捕捉到的G-四链体折叠的早期事件 | Monsen, R. C. | N/A | Early Events in G-quadruplex Folding Captured by Time-Resolved Small-Angle X-Ray Scattering | |
| 平衡运动脊髓回路中的兴奋与抑制 | Chia, R. | N/A | Balancing Excitation and Inhibition in the Locomotor Spinal Circuits | |
| 糖萼生成膜曲率和感知膜曲率的生物物理建模 | Xiao, K. | N/A | Biophysical modeling of membrane curvature generation and curvature sensing by the glycocalyx | |
| 从旋转平均的二维X射线衍射图样中恢复昆虫飞行肌的三维结构 | Iwamoto, H. | N/A | Restoration of 3-D structure of insect flight muscle from a rotationally averaged 2-D X-ray diffraction pattern | |
| 膜辅助Aβ40聚集途径 | Muhammedkutty, F. N. K. | N/A | Membrane-assisted Aβ40 aggregation pathways | |
| 使用多重生物传感器条形码校准基于FRET的生物传感器 | Wu, J.-W. | N/A | Calibration of FRET-based biosensors using multiplexed biosensor barcoding | |
| 利用基于模拟的推理从一维细胞轨迹中估计细胞力学参数 | Heyn, J. | N/A | Cell-mechanical parameter estimation from 1D cell trajectories using simulation-based inference | |
| 模拟鼻窦粘液清除：活性表面衬里的产液腔内的薄膜流动 | Desai, N. | N/A | Modelling mucus clearance in sinuses: thin-film flow inside a fluid-producing cavity lined with an active surface | |
| 可再生活性物质中的分离、有限时间弹性奇异性和粗化现象 | Roychowdhury, A. | N/A | Segregation, Finite Time Elastic Singularities and Coarsening in Renewable Active Matter | |
| 伴侣介导的异型相分离阻止朊蛋白病理性Y145Stop变体的淀粉样形成 | Arora, L. | N/A | Chaperone-mediated heterotypic phase separation prevents the amyloid formation of the pathological Y145Stop variant of the prion protein | |
| Aquavert：用于微生物垂直游泳的成像和微流体技术 | Obenshain, H. B. | N/A | Aquavert: Imaging and Microfluidics for Vertical Swimming of Microorganisms | |
| 运动持续时间影响运动后血容量增多的程度，但不影响急性高强度间歇运动中促红细胞生成素的反应 | Tripp, T. R. | N/A | Session duration affects the magnitude of post-exercise hypervolemia but not the erythropoietin response to acute high-intensity interval exercise | |
| 精确而非预测：身体所有权错觉作为贝叶斯推理下在线精确适应的结果 | Novicky, F. | N/A | Precision not prediction: Body-ownership illusion as a consequence of online precision adaptation under Bayesian inference | |
| 下一代Cu(II)选择性肽穿梭体可防止Cu(Aβ)诱导的毒性和同种异型海马切片中的小胶质细胞活化 | Okafor, M. | N/A | Next-generation Cu(II) selective peptide shuttles prevent Cu(Aβ)-induced toxicity and microglial activation in organotypic hippocampal slices | |
| 盲人足球运动员的楔前叶/后扣带皮层灰质体积增加 | Morita, T. | N/A | Gray matter volume increase in the retrosplenial/posterior cingulate cortices of blind soccer players | |
| 孟加拉国感染志贺氏菌的幼儿中，O特异性多糖（OSP）特异性功能抗体反应有限 | Bernshtein, B. | N/A | Limited O-specific polysaccharide (OSP)-specific functional antibody responses in young children with Shigella infection in Bangladesh | |
| 拓扑驱动法发现跨膜蛋白S-棕榈酰化 | Forrester, M. T. | N/A | Topology-Driven Discovery of Transmembrane Protein S-Palmitoylation | |
| 中医药调节心脏微血管内皮细胞在多种损伤模型中的机制：一项全面的系统综述 | Zhou, H. | N/A | Mechanisms of traditional Chinese medicine in modulating cardiac microvascular endothelial cells in various injury models: A comprehensive systematic review | |
| GSK-3β的错误调控通过Shot和Tau导致轴突微管卷曲 | Voelzmann, A. | N/A | Mis-regulation of GSK-3β causes axonal microtubule curling through Shot and Tau | |
| 损失还是重新分配？一种更好地估计由于人类活动增加而导致的动物分布和数量区域变化的途径 | Mercker, M. | N/A | Loss or redistribution? A better way of estimating regional changes in animal distribution and numbers caused by increased human activities | |
| 推断蜜蜂遗传多样性的长期和短期决定因素：养蜂影响与保护策略 | Leroy, T. | N/A | Inferring long-term and short-term determinants of genetic diversity in honey bees: Beekeeping impact and conservation strategies | |
| 东非和南非人群中高分辨率I类HLA-A、-B和-C的多样性 | Ndhlovu, Z. | N/A | High Resolution Class I HLA -A, -B, and -C Diversity in Eastern and Southern African Populations | |
| 噬菌体L衣壳装饰蛋白的模板化三聚作用 | Woodbury, B. M. | N/A | Templated trimerization of the phage L decoration protein on capsids | |
| 细菌毒素SsdA对单链DNA胞嘧啶脱氨作用的序列上下文无关的结构基础 | Yin, L. | N/A | Structural basis for sequence context-independent single-stranded DNA cytosine deamination by the bacterial toxin SsdA | |
| 基于表面的与基于体素的有限元头部模型：应变响应的比较分析 | Zhou, Z. | N/A | Surface-Based vs. Voxel-Based Finite Element Head Models: Comparative Analyses of Strain Responses | |
| 孔雀羽毛角蛋白的初步结构 | Russ, P. | N/A | Feather keratin in Pavo cristatus: A tentative structure | |
| 细菌表面的直接接触会引发宿主吞噬体膜的相分离。 | Bhausaheb, A. J. | N/A | Direct contact of the bacterial surface induces phase separation in the host phagosome membrane | |
| 内分泌干扰化学物质非单调剂量反应的潜在机制：系统负反馈调节的干扰 | Shi, Z. | N/A | Interference with Systemic Negative Feedback Regulation as a Potential Mechanism for Nonmonotonic Dose-Responses of Endocrine-Disrupting Chemicals | |
| 用餐期间进行对话所花费的时间可以预测默认网络功能：来自被动移动感知和fMRI研究的证据。 | Bhatt, D. | N/A | Time spent in conversation over meals predicts default network function: Evidence from a passive mobile-sensing and fMRI study. | |
| 信心评分数据的信心-噪声信心增强（CNCB）模型 | Mamassian, P. | N/A | The Confidence-Noise Confidence-Boost (CNCB) model of confidence rating data | |
| TGFβ使类似肺泡的巨噬细胞在TLR2激活后诱导I型干扰素 | Thomas, S. M. | N/A | TGFβ primes alveolar-like macrophages to induce type I IFN following TLR2 activation | |
| 海滨沉积物中分离放线菌的次级代谢产物生物活性分析 | Shubhro, K. | N/A | Bioactivity Analysis of Secondary Metabolites from Actinomycetes' Isolated from Coastal Sediments | |
| 呼吸上皮的三维纳米结构揭示了运动纤毛-根丝-线粒体之间的通信轴 | Vijayakumaran, A. | N/A | 3D nanoscale architecture of the respiratory epithelium reveals motile cilia-rootlets-mitochondria axis of communication | |
| Pcbp1 在多能性背景下限制 Oct4 的表达 | Bakhmet, E. I. | N/A | Pcbp1 constrains Oct4 expression in the context of pluripotency | |
| 人类胰岛素受体外域的深度突变扫描，以指导胰岛素抵抗的精准治疗 | Aslanzadeh, V. | N/A | Deep mutational scanning of the human insulin receptor ectodomain to inform precision therapy for insulin resistance | |
| 单分子磁镊揭示了TAV2b衍生肽能够解旋并稳定双链RNA | Rashid, Z. M. | N/A | Single-molecule magnetic tweezers reveals that TAV2b-derived peptides underwind and stabilize double-stranded RNA | |
| 超分子酶-肽凝胶用于局部治疗性生物催化 | Fuchs, M. | N/A | Supramolecular Enzyme-Peptide Gels for Localized Therapeutic Biocatalysis | |
| AI驱动的耐碱性蛋白质进化及其在大规模生产中的应用 | Kang, L. | N/A | AI-enabled Alkaline-resistant Evolution of Protein to Apply in Mass Production | |
| 基于同步加速器的质子和基于直线加速器电子的超高剂量率照射在急性胃肠道毒性方面存在不一致。 | Liu, K. | N/A | Discordance in acute gastrointestinal toxicity between synchrotron-based proton and linac-based electron ultra-high dose rate irradiation | |
| 在PURE系统中从丙酮酸再生ATP | Yadav, S. | N/A | ATP Regeneration from Pyruvate in the PURE System | |
| 测试免疫计算模型——一项受邀挑战，旨在预测百日咳疫苗接种结果 | Shinde, P. | N/A | Putting computational models of immunity to the test - an invited challenge to predict B. pertussis vaccination outcomes | |
| 邻近标记技术定义了小鼠和原代人巨噬细胞吞噬体腔的蛋白质组 | Allsup, B. L. | N/A | Proximity labeling defines the phagosome lumen proteome of murine and primary human macrophages | |
| 一种1型免疫-基质细胞网络介导了疾病耐受性和肠道感染的屏障保护作用 | Westfall, S. | N/A | A type 1 immune-stromal cell network mediates disease tolerance and barrier protection against intestinal infection | |
| 加拿大原住民传统疗法对伤口感染模拟条件下MRSA浮游和生物膜细菌的抗菌潜力 | Rieger, C. D. | N/A | The antimicrobial potential of traditional remedies of Indigenous Peoples from Canada against MRSA planktonic and biofilm bacteria in wound-infection mimetic conditions | |
| 对美国犬钩虫感染相关风险因素及苯并咪唑F167Y抗药性标记多态性的研究 | Jimenez Castro, P. D. | N/A | Investigation of risk factors associated with Ancylostoma spp. infection and the benzimidazole F167Y resistance marker polymorphism in dogs from the United States | |
| 白纹夜蛾（鳞翅目：Hyles lineata）的性别特异性化学感觉基因表达表明气味结合蛋白在寄主植物选择中发挥作用 | Godfrey, R. K. | N/A | Sex-specific chemosensory gene expression in the whitelined sphinx moth (Lepidoptera: Hyles lineata) suggests a role for odorant-binding proteins in host plant choice | |
| 通过CTCF结合活性的获得和丧失来鉴定有害的非编码变异 | Tubbs, C. | N/A | Identifying deleterious noncoding variation through gain and loss of CTCF binding activity | |
| 增强子激活来自染色体外DNA中的转座元件 | Kraft, K. | N/A | Enhancer activation from transposable elements in extrachromosomal DNA | |
| 通过线粒体酶复合物的计算基因组学推进骨髓增生异常综合征的变异表型分析 | Dong, J. | N/A | Advancing Variant Phenotyping in Myelodysplastic Syndromes via Computational Genomics of Mitochondrial Enzyme Complexes | |
| 依赖二聚化的凝胶状dsDNA凝聚作用是人类cGAS激活的基础 | Sohn, J. | N/A | Dimerization-dependent gel-like condensation with dsDNA underpins the activation of human cGAS | |
| 机器学习驱动的高精度细胞液滴生物打印优化 | Shin, J. | N/A | Machine Learning Driven Optimization for High Precision Cellular Droplet Bioprinting | |
| 投影统计 ProST 在线统计评估数据投影分析中的组分离 | Salem, D. | N/A | Projection Statistics ProST Online statistical assessment of group separation in data projection analysis | |
| 通过精确的细胞周期状态映射揭示的细胞身份将数据模式联系起来 | Alahmari, S. | N/A | Cell identity revealed by precise cell cycle state mapping links data modalities | |
| MYC 与 IIa 类 HDAC 抑制剂联合作用可增强非小细胞肺癌中的线粒体功能障碍 | Park, J. | N/A | MYC plus class IIa HDAC inhibition potentiates mitochondrial dysfunction in non-small cell lung cancer | |
| 基于图曲率的免疫检查点响应生物标志物发现流程 | Bannon, J. J. | N/A | A Graph Curvature-Based Pipeline for Discovering Immune Checkpoint Response Biomarkers | |
| 结合循环性发热与紫锥菊苷对胰腺癌细胞PANC-1产生协同治疗效果 | Chen, W.-T. | N/A | Combination of cycling hyperthermia and Echinacoside creates synergistic curing effect on pancreatic cancer PANC-1 cells | |
| 小鼠动脉粥样硬化斑块中细胞的分子和时空特征 | Hou, P. | N/A | Molecular and spatiotemporal characterization of cells in murine atherosclerotic plaques | |
| 额叶异常活动与唤醒水平和行动启动及反应力度相关 | Klein, F. | N/A | Aberrant prefrontal activity and arousal level correlate with action initiation and response vigor | |
| MIP3α-RelMtb鼻内DNA疫苗在小鼠和猕猴中诱导了反应性T细胞向肺部的浸润。 | Gordy, J. T. | N/A | MIP3α-RelMtb intranasal DNA vaccination induces reactive T-cell infiltration into the lungs in mice and macaques | |
| 喜马拉雅长尾叶猴的群体遗传学及其分类学意义 | M R, S. | N/A | Population genetics of Himalayan langurs and its taxonomic implications | |
| 全基因组鉴定稳定的RNA-染色质相互作用 | Wen, X. | N/A | Genome-wide identification of stable RNA-chromatin interactions | |
| 人类增强子体内诱变敏感性图谱 | Kosicki, M. | N/A | Mutagenesis Sensitivity Mapping of HumanEnhancers In Vivo | |
| 三碘甲状腺原氨酸和黄芩素的双重干预双向上调Klotho，减轻老年BALB/c小鼠慢性肾脏病及其并发症 | Mohanty, S. K. | N/A | A Dual intervention of Triiodothyronine and Baicalein bi-directionally upregulates Klotho with attenuation of chronic kidney disease and its complications in aged BALB/c mice | |
| 使用多种机器学习框架对病毒逃逸语言模型进行系统评估 | Allman, B. | N/A | A systematic evaluation of the language-of-viral-escape model using multiple machine learning frameworks | |
| 增强Vaxign-DL以预测疫苗候选者，加入ESM生成的特征 | Chen, Y. | N/A | Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features | |
| 胎鼠在子宫内的脑脊液压力：外部因素对脑室空间施加压力 | Tsujikawa, K. | N/A | CSF pressure in fetal mice in utero: External factors pressurize the intraventricular space | |
| 基于膜的芽殖酵母细胞器应激反应 | Sheng, P. | N/A | Stress response of membrane-based cell organelles in budding yeast | |
| 解析斑马鱼早期胚胎发育过程中细胞特异性转录异质性和可变剪接 | Lin, X. | N/A | Deciphering the Cell Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish | |
| # BioRxiv 2024-09-07 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 哺乳动物前脑中谷氨酸能突触的分子结构 | Peukes, J. | N/A | The molecular infrastructure of glutamatergic synapses in the mammalian forebrain | |
| 基于物种独立性假设的随机群落模型中的Jaccard相异度 | Iritani, R. | N/A | Jaccard dissimilarity in stochastic community models based on the species-independence assumption | |
| 婴儿的大脑中视觉类别表征何时出现？ | Yan, X. | N/A | When Do Visual Category Representations Emerge in Infants' Brains? | |
| 用于分析光纤光度实验中试验级时间动态的统计框架 | Loewinger, G. | N/A | A Statistical Framework for Analysis of Trial-Level Temporal Dynamics in Fiber Photometry Experiments | |
| 物种共存边缘距离的分布 | DESALLAIS, M. | N/A | The distribution of distances to the edge of species coexistence | |
| 资源可用性与亲本觅食策略对幼年麻雀个体特化作用的影响 | Ricote, N. | N/A | The Interplay of Resource Availability and Parent Foraging Strategies on Juvenile Sparrow Individual Specialization | |
| Pannexin 1 和 Pannexin 3 在皮肤鳞状细胞癌的肿瘤发生特性中发挥不同的调控作用。 | O'Donnell, B. L. | N/A | Pannexin 1 and Pannexin 3 differentially regulate the tumorigenic properties of cutaneous squamous cell carcinoma | |
| 训练有素的跑步者中长距离跑步表现指标受先进跑鞋技术钉的影响 | Rodrigo-Carranza, V. | N/A | Influence of advanced footwear technology spikes on middle- and long-distance running performance measures in trained runners | |
| 通过蛋白质结构扩散实现精确构象采样 | Fan, J. | N/A | Accurate Conformation Sampling via Protein Structural Diffusion | |
| 莱姆病螺旋体伯氏疏螺旋体外表面蛋白C（OspC）的精细人源B细胞表位图谱 | Freeman-Gallant, G. | N/A | A refined human linear B cell epitope map of Outer surface protein C (OspC) from the Lyme disease spirochete, Borreliella burgdorferi | |
| 脂质-siRNA偶联物进入血管周运输机制，并在中枢神经系统中实现广泛而持久的敲低效果。 | Sorets, A. | N/A | Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system | |
| 量化为向量场的神经网络 | Szeier, S. | N/A | Neuronal networks quantified as vector fields | |
| 鸟类白蛋白糖基化速率的变异表明其对相对高血糖的抵抗力，而非符合生命节奏综合征假说。 | Moreno Borrallo, A. | N/A | Variation in albumin glycation rates in birds suggests resistance to relative hyperglycaemia rather than conformity to the pace of life syndrome hypothesis | |
| 有袋类动物的免疫保护机制受到抗菌肽cathelicidin增强子共享和基因簇重复的影响。 | Park, J. | N/A | Marsupial immune protection is shaped by enhancer sharing and gene cluster duplication of cathelicidin antimicrobial peptides | |
| 组蛋白去甲基酶LSD1在隐球菌感染期间调节脂质稳态 | Lohia, G. K. | N/A | Histone demethylase LSD1 regulates lipid homeostasis duringCryptococcus neoformans infection | |
| 食品污染物脱氧雪腐镰刀菌烯醇的低浓度可引发凋亡并损害促性腺激素释放激素诱导的垂体类促性腺细胞中黄体生成素分泌。 | Cai, G. | N/A | Low concentrations of the food contaminant Deoxynivalenol trigger apoptosis and impair GnRH-induced LH secretion in pituitary gonadotrope-like cells | |
| 葡萄藤细胞对生理剂量乙醇的反应，其中包括诱导对热应激的抗性。 | Diot, A. | N/A | Responses of grapevine cells to physiological doses of ethanol, among which induced resistance to heat stress | |
| 在不对称细胞分裂过程中，线粒体的非随机分离有助于子细胞命运的分化。 | Segos, I. | N/A | Non-random segregation of mitochondria during asymmetric cell division contributes to cell fate divergence in daughter cells | |
| 巨噬细胞内在的MDA5-IRF5轴驱动HIV-1 icRNA诱导的炎症反应 | Ramaswamy, S. | N/A | Macrophage-intrinsic MDA5-IRF5 axis drives HIV-1 icRNA-induced inflammatory responses | |
| 赖氨酸82的乙酰化通过破坏其核输入，启动TDP-43的核功能丧失。 | Zhang, S. | N/A | Acetylation of lysine 82 initiates TDP-43 nuclear loss of function by disrupting its nuclear import | |
| 几何推导的动作电位标记用于模型开发：一种有原则的方法？ | Clerx, M. | N/A | Geometrically-derived action potential markers for model development: a principled approach? | |
| 依赖于压电效应（PIEZO）的微环境机械感应对于肠道干细胞命运决定和维持至关重要。 | Baghdadi, M. B. | N/A | PIEZO-dependent mechano-sensing of the niche is essential for intestinal stem cell fate decision and maintenance | |
| 在表皮发育过程中，隔膜连接成分在信号通路调控和细胞极性方面具有独特的非封闭功能 | Holtwick, V. | N/A | Distinct Non-occluding Functions of Septate Junction Components in Signaling Pathway Regulation and Cell Polarity During Epithelial Development | |
| α-连环蛋白的磷酸化在有丝分裂期间升高，以抵抗顶端圆化和上皮屏障泄漏。 | Le, P. M. | N/A | α-catenin phosphorylation is elevated during mitosis to resist apical rounding and epithelial barrier leak | |
| PI3K/AKT信号通路通过c-myc介导应激诱导的淀粉样蛋白聚集 | Lacroix, E. | N/A | PI3K/AKT Signaling Mediates Stress-Inducible Amyloid Aggregation Through c-myc | |
| 白色念珠菌中的五EF-手蛋白Pef1在膜扰动位点发挥作用，以支持极性生长和膜完整性。 | Weichert, M. | N/A | The penta-EF-hand protein Pef1 of Candida albicans functions at sites of membrane perturbation to support polarized growth and membrane integrity | |
| 节点调制器（NOMO）是一种承载力的跨膜蛋白，对于肌肉分化是必需的。 | Naughton, B. | N/A | Nodal Modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation | |
| GDF11分泌细胞移植能有效改善与年龄相关的肺纤维化 | Nagy, A. | N/A | GDF11 secreting cell transplant efficiently ameliorates age-related pulmonary fibrosis | |
| Pax转录因子EGL-38将EGFR信号传导与秀丽隐杆线虫阴门中特定细胞类型的顶端细胞外基质的组装联系起来。 | Schmidt, H. F. | N/A | The Pax transcription factor EGL-38 links EGFR signaling to assembly of a cell-type specific apical extracellular matrix in the Caenorhabditis elegans vulva | |
| 发育中的人类视网膜的睫状缘区在妊娠晚期之前一直维持着视网膜祖细胞。 | Eldred, K. C. | N/A | Ciliary marginal zone of the developing human retina maintains retinal progenitor cells until late gestational stages | |
| Wnt/β-连环蛋白信号传导支撑了肝片吸虫幼虫的生长和发育。 | Armstrong, R. | N/A | Wnt/β-catenin signalling underpins juvenile Fasciola hepatica growth and development | |
| RNA结合调控级联控制果蝇雄性生殖系干细胞谱系中从增殖到分化的转变 | Harris, D. E. | N/A | An RNA binding regulatory cascade controls the switch from proliferation to differentiation in the Drosophila male germ line stem cell lineage | |
| 盐诱导激酶对牙槽骨发育、稳态及牙槽窝愈合的调控作用 | Tokavanich, N. | N/A | Control of alveolar bone development, homeostasis, and socket healing by salt inducible kinases | |
| 一种简单的围产期哺乳动物卵巢免疫组织化学方法揭示了由DNA损伤和非联会引起的卵母细胞凋亡的不同动力学。 | Kogo, H. | N/A | A simple immunohistochemical method for perinatal mammalian ovaries revealed different kinetics of oocyte apoptosis caused by DNA damage and asynapsis. | |
| 胰岛初级纤毛中轴丝动力蛋白的扩展显微镜观察 | Dong, X. | N/A | Expansion microscopy of axonemal dyneins in islet primary cilia | |
| 单细胞转录组分析揭示CD34作为人类窦房结起搏细胞的新型标志物 | Lim, A. A. | N/A | Single-cell transcriptome analysis reveals CD34 as a novel marker of human sinoatrial node pacemaker cardiomyocytes | |
| 钙蛋白酶在膜修复过程中调控含有膜联蛋白的微囊泡的分泌 | Williams, J. K. | N/A | Calpains Orchestrate Secretion of Annexin-containing Microvesicles during Membrane Repair | |
| 果蝇肌生成抑制因子Him基因对于成年肌肉功能和肌肉干细胞的维持至关重要。 | Mitchell-Gee, R. | N/A | The Drosophila myogenic inhibitor Him gene is essential for adult muscle function and muscle stem cell maintenance | |
| 刺胞动物胚胎中的平面细胞极性协调为动物体轴的进化提供了线索。 | Uveira, J. | N/A | Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution | |
| 中等剂量砷暴露会损害小鼠肾单位的形成 | Alonso, C. A. I. | N/A | Mouse nephron formation is impaired by moderate-dose arsenical exposure | |
| 计算机靶点识别揭示IL12B为小分子药物开发的候选靶点 | Tanner, T. J. | N/A | In Silico Target Identification Reveals IL12B as a Candidate for Small Molecule Drug Development | |
| 腺样囊性癌中HLA I类分子的可逆性下调 | Li, A. | N/A | Reversible Downregulation of HLA Class I in Adenoid Cystic Carcinoma | |
| 利用作物模型引导的机器学习方法，从数据稀疏的田间试验中估算土壤矿质氮 | Gupta, R. | N/A | Estimating soil mineral nitrogen from data-sparse field experiments using crop model-guided machine learning approach | |
| 在莱茵衣藻中敲除羧基转移酶互作蛋白1（CTI1）使其油脂含量提高了五倍，同时不影响细胞生长。 | Li, Z. | N/A | Knocking out the carboxyltransferase interactor 1 (CTI1) in Chlamydomonas boosted oil content by fivefold without affecting cell growth | |
| 远程缺血预处理通过CD36介导的吞噬作用减轻跨神经元退化并促进中风恢复。 | Ju, H. | N/A | Remote ischemic conditioning attenuates transneuronal degeneration and promotes stroke recovery via CD36-mediated efferocytosis. | |
| 寡聚原花青素对中性粒细胞胞外陷阱的抑制作用通过肠-肾轴减轻化疗诱导的慢性肾损伤 | Luan, Y. | N/A | Inhibition on neutrophil extracellular traps by oligomeric procyanidins alleviate chemotherapy-induced chronic kidney injury via gut-kidney axis | |
| 高效多重非病毒工程化及扩增多克隆γδ CAR-T细胞用于免疫治疗 | Bridge, J. | N/A | Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy | |
| 副粘病毒基质蛋白通过与细胞质中的外显子连接复合体相互作用，调节宿主细胞的翻译过程。 | Hung, C.-T. | N/A | Paramyxovirus matrix proteins modulate host cell translation via exon-junction complex interactions in the cytoplasm | |
| 澳大利亚犬钩虫（Ancylostoma caninum）中广泛存在苯并咪唑抗性单核苷酸多态性（SNPs） | Abdullah, S. | N/A | Widespread occurrence of benzimidazole resistance SNPs in the canine hookworm, Ancylostoma caninum, in Australia | |
| 数据发布：使用FIB-SEM和机器学习对P7小鼠组织微观结构进行高分辨率成像和分割 | Ackerman, D. | N/A | Data Release: High-Resolution Imaging and Segmentation of P7 Mouse Tissue Microarchitecture Using FIB-SEM and Machine Learning | |
| 基因型和年龄对无菌SCID猪仔体内特定微生物群的影响 | Widmer, K. M. | N/A | Effect of Genotype and Age on a Defined Microbiota in Gnotobiotic SCID Piglets | |
| 鬣蜥属（Chamaeleo calyptratus，又称面纱变色龙）染色体规模的基因组组装和注释为爬行动物的进化和发育机制提供了深入见解。 | Shylo, N. | N/A | Chamaeleo calyptratus (veiled chameleon) chromosome-scale genome assembly and annotation provides insights into the evolution of reptiles and developmental mechanisms. | |
| 老年小鼠表现出更快的静脉注射阿片类药物自我给药获取速度，但对摄入量的影响不一。 | Sharpe, A. L. | N/A | Aged mice exhibit faster acquisition of intravenous opioid self-administration with variable effects on intake | |
| 为体外膜氧化治疗期间的医疗设备进行计算机模拟临床试验生成虚拟患者数据 | Landoll, M. | N/A | Generating virtual patient data for in-silico clinical trials of medical devices during extracorporeal membrane oxygenationtreatment | |
| 全原子连续恒定pH分子动力学中的力场限制 | Peeples, C. | N/A | Force Field Limitations of All-Atom Continuous Constant pH Molecular Dynamics | |
| 人诱导多能干细胞衍生的心肌细胞的激发计算研究 | Shetty, R. | N/A | Computational Study of the Excitation of Human Induced Pluripotent Stem-Cell Derived Cardiomyocytes | |
| T1D患者和进展者的性别特异性细胞因子、趋化因子和生长因子特征 | Girdhar, K. | N/A | Sex-Specific Cytokine, Chemokine, and Growth Factor Signatures in T1D Patients and Progressors | |
| 城市化的生态和进化影响：应用因果建模框架 | Borden, J. B. | N/A | Ecological and evolutionary impacts of urbanization: applying a causal modeling framework | |
| CD4+Foxp3E2+调节性T细胞频率可预测乳腺癌的预后和复发。 | Fusco, C. | N/A | CD4+Foxp3E2+ regulatory T cell frequency predicts breast cancer prognosis and recurrence | |
| 在乳头状病毒感染后两周，侵袭性癌症和自发性消退 | Bilger, A. | N/A | Invasive cancer and spontaneous regression two weeks after papillomavirus infection | |
| 探索辣椒素对胃癌细胞基因表达及化疗增敏作用的影响 | Meng, W. | N/A | Exploring the effect of capsaicin on gene expression and chemotherapy sensitization in gastric cancer cells | |
| 特定于脑桥的轴突微环境支持新发的胶质瘤生成 | Xie, Z. | N/A | A pontine-specific axonal niche supports de novo gliomagenesis | |
| 铁死亡与细胞凋亡的相互作用及其通过BH3模拟物的调节 | Qiu, Y. | N/A | Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics | |
| Claudin-4 对细胞核-细胞周期交叉对话的重塑维持了卵巢肿瘤基因组的稳定性，并推动了对诱导基因组不稳定性药物的抗性。 | Bitler, B. G. | N/A | Claudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents. | |
| 肾母细胞瘤中亚型特异性的进化模式及与临床相关的基因组不稳定性 | Cresswell, G. D. | N/A | Subtype-specific Patterns of Evolution and Clinically Relevant Genomic Instability in Wilms Tumour | |
| 温度敏感的谷氨酸门控AMPA亚型iGluRs | Kumar Mondal, A. | N/A | Temperature Sensitive Glutamate Gating of AMPA-subtype iGluRs | |
| 将细菌素合成多重化以杀灭和预防抗菌药物耐药性 | Quintero-Yanes, A. | N/A | Multiplexing bacteriocin synthesis to kill and prevent antimicrobial resistance | |
| C7取代的喹啉作为鲍曼不动杆菌中AdeG外排泵的有效抑制剂 | Zhu, Y. | N/A | C7-substituted Quinolines as Potent Inhibitors of AdeG Efflux Pumps in Acinetobacter baumannii | |
| 人转铁蛋白和乳铁蛋白协同支持脑膜炎奈瑟菌在小鼠鼻咽部的定殖 | Lee, I. S. | N/A | Human transferrin and lactoferrin cooperatively support Neisseria meningitidis colonization in the murine nasopharynx | |
| 优化数字PCR检测方法以实现地表水中多重微生物来源追踪 | Ghosh, S. | N/A | Optimizing Digital PCR Assays for Multiplexed Microbial Source Tracking in Surface Waters | |
| 社区范围内的相互作用维持了地热泉生境中的生命 | Stephens, T. G. | N/A | Community-wide interactions sustain life in geothermal spring habitats | |
| 工程改造亚洲象TP53：TP53逆转录基因敲除激活了常见且独特的与癌症相关的通路 | Karpinski, E. | N/A | Engineering Asian elephant TP53: TP53 retrogene knockouts activate common and unique cancer-relevant pathways | |
| 使用CycloneSEQ高效构建完整基因组以填补细菌草图组装中的空缺 | Liang, H. | N/A | Efficiently Constructing Complete Genomes with CycloneSEQ to Fill Gaps in Bacterial Draft Assemblies | |
| 来自Thermotoga naphthophila的GH10家族热稳定木聚糖酶的3D建模：重组木聚糖酶的特性研究 | Waris, A. | N/A | 3D modeling of thermostable xylanase from Thermotoga naphthophila a member of GH10 family: characterization studies of recombinant xylanase | |
| Vps4底物结合及其耦合机制：Vps4p底物招募与从自抑制中释放 | Wienkers, H. | N/A | Vps4 substrate binding and coupled mechanisms of Vps4p substrate recruitment and release from autoinhibition | |
| H/ACA snoRNP在加入核心90S前体核糖体之前，引导核糖体RNA亚域在卫星颗粒中进行折叠。 | Fischer, P. | N/A | H/ACA snoRNP guides ribosomal RNA subdomain folding in a satellite particle before joining the core 90S pre-ribosome | |
| 人类DNA复制起始位点通过5-甲基脱氧胞苷的氧化作用在表观遗传学上被指定。 | Krude, T. | N/A | Human DNA replication initiation sites are specified epigenetically by oxidation of 5-methyl-deoxycytidine | |
| 抑制特定Zn2+依赖性DUB活性及炎症的分子胶 | Chandler, F. | N/A | Molecular glues that inhibit specific Zn2+-dependent DUB activity and inflammation | |
| 通过部分酶解植物细胞壁实现活体植物蛋白质的直接核递送 | Gu, Q. | N/A | Direct Nuclear Delivery of Proteins on Living Plant via Partial Enzymatic Cell Wall Digestion | |
| 选择性激动肝脏和肠道FXR可预防肠外喂养新生猪的胆汁淤积和肠道萎缩 | Jiang, Y. | N/A | Selective Agonism of Liver and Gut FXR Prevents Cholestasis and Intestinal Atrophy in Parenterally Fed Neonatal Pigs | |
| 不同吸湿性肥料颗粒的离散元模型构建及施肥排放验证 | Chen, X. F. | N/A | Construction of Discrete Element Model of Different Moisture Hygroscopic Fertilizer Particles and Fertilizer Discharging Verification | |
| 高粱通过根系分泌物进行的邻近感知影响植物生理和生产力 | Ben-Zeev, S. | N/A | Neighbor sensing through rhizodeposits in sorghum affects plant physiology and productivity | |
| 哺乳动物类胚胎发育的蛋白质组图谱及时间动态变化 | Garge, R. K. | N/A | The proteomic landscape and temporal dynamics of mammalian gastruloid development | |
| AxonFinder：肿瘤侵袭神经纤维的自动分割 | Ait-Ahmad, K. | N/A | AxonFinder: Automated segmentation of tumor innervating neuronal fibers | |
| 大型齿鲸种内体型变异的总结 | McClure, J. | N/A | A summary of intraspecific size variation for large odontocetes | |
| 羊角中CASP14基因的组织特异性及功能位点分析 | Lu, X. | N/A | Tissue-specific and functional loci analysis of CASP14 gene in the sheep horn | |
| 离开补丁的决定和与学生相关的唤醒系统 | Marzecova, A. | N/A | Patch-leaving decisions and pupil-linked arousal systems | |
| 英国版爱荷华辅音感知测试 | Guo, X. | N/A | British Version of the Iowa Test of Consonant Perception | |
| 星形胶质细胞对EcoHIV感染小鼠可卡因运动性敏感化的调控 | Xie, Q. | N/A | Astrocytic Regulation of Cocaine Locomotor Sensitization in EcoHIV Infected Mice | |
| 酒精饮用、焦虑及BNST神经元兴奋性的CRF神经元中食欲素受体信号传导的性别特异性作用 | Ma, Y. | N/A | Sex-Specific Roles of Hypocretin Receptor Signaling in CRF Neurons on Alcohol Drinking, Anxiety, and BNST Neuronal Excitability | |
| 历史驱动的干扰抑制和目标增强的空间参考框架 | Ilksoy, Y. | N/A | The spatial reference frame of history-driven distractor suppression and target enhancement | |
| 肌球蛋白XVA异构体参与了听觉毛细胞中依赖于机械转导的肌动蛋白细胞骨架重塑过程。 | Lopez-Porras, A. I. | N/A | Myosin XVA isoforms participate in the mechanotransduction-dependent remodeling of the actin cytoskeleton in auditory stereocilia | |
| 通过模拟肿瘤微环境的共培养实验鉴定增强NK细胞肿瘤杀伤活性的小分子 | Binici, A. | N/A | Identification of small molecule enhancers of NK cell tumoricidal activity via a tumor microenvironment-mimicking co-culture assay | |
| 针对结核分枝杆菌持久菌的DNA疫苗可缩短治愈结核病所需的治疗时间。 | Karanika, S. | N/A | Therapeutic DNA Vaccine Targeting Mycobacterium tuberculosis Persisters Shortens Curative Tuberculosis Treatment | |
| 线粒体超活性和活性氧驱动对黄热病病毒-17D减毒活疫苗的先天免疫 | Muccilli, S. G. | N/A | Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine | |
| 来自海洋缺氧区的蓝细菌同时编码I型和II型核酮糖-1,5-二磷酸羧化酶/加氧酶（Rubisco）。 | Jaffe, A. L. | N/A | Cyanobacteria from marine oxygen deficient zones encode both form I and form II rubiscos | |
| 多菌株噬菌体诱导的细菌感染清除 | Marchi, J. | N/A | Multi-strain phage induced clearance of bacterial infections | |
| T型电压门控钙通道CaV3.1作为多杀性巴氏杆菌毒素的候选受体，并参与了该毒素引起的呼吸上皮屏障破坏。 | Bi, H. | N/A | The T-type voltage-gated Ca2+ channel CaV3.1 as a candidate receptor for Pasteurella multocida toxin and contributes to the disruption of respiratory epithelial barrier induced by the toxin | |
| 合理选择TbpB变体阐明了针对淋病奈瑟菌的广谱覆盖双价疫苗配方 | Fegan, J. E. | N/A | Rational selection of TbpB variants elucidates a bivalent vaccine formulation with broad spectrum coverage against Neisseria gonorrhoeae | |
| 磷酸戊糖途径保护大肠杆菌免受抗生素致死性影响 | Seregina, T. | N/A | Pentose Phosphate Pathway Protects E. coli from Antibiotic Lethality | |
| 通过小标签人工细菌E3连接酶进行蛋白质降解 | Warming, S. | N/A | Protein degradation by small tag artificial bacterial E3 ligase | |
| 欧洲森林虫害爆发概率：基于六种森林昆虫特征校准的通用模型 | COLLOT, D. | N/A | Probability of outbreaks of forest insects in Europe: a generic model calibrated on six forest insect profiles | |
| 地中海中的海蜇（Rhopilema nomadica）：分子证据支持其迁移，并提出关于其扩散的生态假说 | Kuplik, Z. | N/A | Rhopilema nomadica in the Mediterranean: molecular evidence for migration and ecological hypothesis regarding its proliferation | |
| 重组塑造了wtf减数分裂驱动因子的多样化 | Wang, Y. | N/A | Recombination shapes the diversification of the wtf meiotic drivers | |
| 探索新天地：印度谷子苋的成功适应与基因组完整性 | Singh, A. | N/A | Going New Places: Successful Adaptation and Genomic Integrity of Grain Amaranth in India | |
| 雾化及静脉注射酶替代疗法对黏多糖贮积症II型小鼠的治疗效果 | Shamoun, A. J. | N/A | Nebulized and intravenous enzyme replacement therapy in mice with mucopolysaccharidosis type II | |
| 通过HiCapR技术映射HIV-1 RNA结构、同源二聚体、长程相互作用及持久性结构域 | Zhang, Y. | N/A | Mapping HIV-1 RNA Structure, Homodimers, Long-Range Interactions and persistent domains by HiCapR | |
| 在鼠属中，TCRα和TCRβ位点的独特进化 | Peters, M. A. | N/A | Distinct evolution at TCRα and TCRβ loci in the genus Mus | |
| 在Lachenalia植物中发现的新型Phenuivirus种揭示了5'和3' RNA序列基序之间可能的共同进化 | Dekker, R. J. | N/A | Discovery of a new Phenuivirus species in Lachenalia plants reveals possible co-evolution between 5' and 3' RNA sequence motifs | |
| 早期生活中肠道移动组的动态变化及决定因素 | Fernandez-Pato, A. | N/A | Dynamics and determinants of the gut mobilome in early life | |
| 一种新型机制：胞内铁载体结合的铁离子被线粒体摄取，并在其内部还原为亚铁离子 | Dutta, A. | N/A | A novel mechanism for the uptake of enterobactin-chelated ferric ions by the mitochondria and subsequent reduction to ferrous ions inside | |
| 结构蛋白质组学揭示了孕酮受体的顺序启动机制 | Mann, M. D. | N/A | Structural proteomics defines a sequential priming mechanism for the progesterone receptor | |
| 呼吸复合物I中喹啉阴离子的催化相关性在生物能量转换中的作用 | Zdorevskyi, O. | N/A | Catalytic relevance of quinol anion in biological energy conversion by respiratory complex I | |
| RepeatParam：重复蛋白质参数化算法及重复蛋白质结构分析 | Pretorius, D. | N/A | RepeatParam: Algorithm for Parameterising Repeat Proteins and Analysis of Repeat Protein Architectures | |
| sTREM2的柔性茎域调节其与大脑中磷脂的相互作用 | Saeb, D. | N/A | The flexible stalk domain of sTREM2 modulates its interactions with phospholipids in the brain | |
| 优化合成血管移植物力学行为的计算框架 | Jiang, D. | N/A | A Computational Framework to Optimize the Mechanical Behavior of Synthetic Vascular Grafts | |
| 乙酸和优化硝酸盐水平对Chlorella Sorokiniana混合营养生长及蛋白质动态的影响 | Chen, S. | N/A | Impact of Acetate and Optimized Nitrate Levels on Mixotrophic Growth and Protein Dynamics in Chlorella Sorokiniana | |
| 使用多维逆运动学与平均分段形态学评估临床评估中的关节角度数据。 | Taitano, R. I. | N/A | Evaluating Joint Angle Data for Clinical Assessment Using Multidimensional Inverse Kinematics with Average Segment Morphometry. | |
| 非侵入性细胞膜电位测量的建模：LTSpice仿真与机器学习分析 | Ma, X. | N/A | Modeling of Non-invasive Cell Membrane Potential Measurement: LTSpice Simulation and Machine Learning Analysis | |
| 通过整合小角散射与AlphaFold解析膜蛋白的构象集合 | Lidbrink, S. E. | N/A | Resolving the conformational ensemble of a membrane protein by integrating small-angle scattering with AlphaFold | |
| 表达、纯化及表征大肠杆菌中的二酰化Lipo-YcjN | Trevino, M. A. | N/A | Expression, purification, and characterization of diacylated Lipo-YcjN from Escherichia coli | |
| 协调端粒脱氧核苷酸转移酶dUTP缺口末端标记（TUNEL）与多重迭代免疫荧光技术，能够丰富细胞死亡的空间背景信息。 | Sherman, M. S. | N/A | Harmonizing terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) with multiplexed iterative immunofluorescence enriches spatial contextualization of cell death | |
| 根际细菌能促进防御和营养反应的激活，从而抑制大麦上的蚜虫种群。 | Mbaluto, C. | N/A | Rhizobacteria prime the activation of defence and nutritional responses to suppress aphid populations on barley | |
| 使用综合多组学方法识别的产科综合征之间的胎盘网络差异 | Piekos, S. N. | N/A | Placental Network Differences Among Obstetric Syndromes Identified With An Integrated Multiomics Approach | |
| 通过数学模型理解药物诱导的耐药性 | Sontag, E. D. | N/A | Understanding therapeutic tolerance through a mathematical model of drug-induced resistance | |
| 一种可推广的脑形态异常检测规范深度自编码器：应用于双相情感障碍多站点StratiBip数据集的外部验证框架。 | Sampaio, I. W. | N/A | A generalizable normative deep autoencoder for brain morphological anomaly detection: application to the multi-site StratiBip dataset on bipolar disorder in an external validation framework. | |
| 识别分子梯度塑造视觉运动转换的突触特异性 | Dombrovski, M. | N/A | Gradients of Recognition Molecules Shape Synaptic Specificity of a Visuomotor Transformation | |
| 多发性硬化症中克隆扩增的CD8+ T细胞的抗原特异性 | Mittl, K. | N/A | Antigen-specificity of clonally-enriched CD8+ T cells in multiple sclerosis | |
| 基于病毒样颗粒的疫苗，针对按蚊唾液蛋白TRIO | Francian, A. | N/A | Virus-like particle-based vaccines targeting the Anopheles mosquito salivary protein, TRIO | |
| 异种花粉转移如何影响两种密切相关植物物种的协同进化和共存？ | Morita, K. | N/A | How can interspecific pollen transfer affect the coevolution and coexistence of two closely related plant species? | |
| 在白面卷尾猴（Cebus imitator）中，MHC异质性可能提高从属雄性而非阿尔法雄性的生育成功率。 | Buckner, J. C. | N/A | MHC heterozygosity may increase subordinate but not alpha male siring success in white-faced capuchin monkeys (Cebus imitator) | |
| 端粒到端粒的非洲野生稻（Oryza longistaminata）参考基因组揭示了片段和结构变异 | Guang, X. | N/A | Telomere-to-telomere African wild rice (Oryza longistaminata) reference genome reveals segmental and structural variation | |
| 人类和蝙蝠基因组在COSMIC突变特征下的稳健性 | Song, J.-H. | N/A | Human and bats genome robustness under COSMIC mutational signatures | |
| 信息论：评估基因组人工智能的框架 | Robson, E. S. | N/A | Enformation Theory: A Framework for Evaluating Genomic AI | |
| 活体哺乳动物大脑的光学透明化 | Talei Franzesi, G. | N/A | In Vivo Optical Clearing of Mammalian Brain | |
| Metapipeline-DNA：一个全面的种系与体细胞基因组学Nextflow管道 | Patel, Y. | N/A | Metapipeline-DNA: A Comprehensive Germline & Somatic Genomics Nextflow Pipeline | |
| 蛋白质设计档案（PDA）：40年蛋白质设计的洞见 | Chronowska, M. | N/A | The Protein Design Archive (PDA): insights from 40 years of protein design | |
| 利用深度学习预测非编码突变对单细胞DNA甲基化的影响 | Liu, Z. | N/A | Predicting the effect of non-coding mutations on single-cell DNA methylation using deep learning | |
| DDGemb：利用嵌入和深度学习预测蛋白质在单点和多点变异下的稳定性变化 | Savojardo, C. | N/A | DDGemb: predicting protein stability change upon single- and multi-point variations with embeddings and deep learning | |
| 建模如何由片状伪足驱动的细胞维持持续迁移并与外部障碍物相互作用 | Sadhukhan, S. | N/A | Modelling how lamellipodia-driven cells maintain persistent migration and interact with external barriers | |
| 通过高分辨率原子力显微镜进行动质体DNA的多尺度拓扑分析 | Diggines, B. | N/A | Multiscale topological analysis of kinetoplast DNA via high-resolution AFM | |
| 蛋白质亚基中的可切换构象：揭示二十面体病毒的组装动力学 | Li, S. | N/A | Switchable Conformation in Protein Subunits: Unveiling Assembly Dynamics of Icosahedral Viruses | |
| 一种介导免疫摧毁衰老癌细胞的抗生素 | Casagrande Raffi, G. | N/A | An antibiotic that mediates immune destruction of senescent cancer cells | |
| 基于代理与连续模型在细胞种群建模中的等价性。应用于微流控装置中胶质母细胞瘤的演化 | Arroyo-Vazquez, R. B. | N/A | On the equivalence between Agent-Based and Continuum models for cell population modeling. Application to glioblastoma evolution in microfluidic devices | |
| 泊洛沙姆188在肌营养不良性心肌病中的差异有效性揭示了复杂的病理生理机制。 | Heitzman, J. | N/A | Differential Effectiveness of Poloxamer 188 in Dystrophic Cardiomyopathy Reveals Complex Pathophysiology. | |
| 拟南芥RS2Z32和RS2Z33蛋白是动态剪接因子，其RNA识别基序（RRM）域有助于蛋白质-蛋白质和蛋白质-RNA相互作用。 | Fanara, S. | N/A | The Arabidopsis RS2Z32 and RS2Z33 proteins are dynamic splicing factors whose RNA recognition motif (RRM) domain contributes to protein-protein and protein-RNA interactions | |
| 心律失常的神经表征：预测编码视角 | Reinfeld, P. | N/A | Neural Representations of Extrasystoles: A Predictive Coding Perspective | |
| 机械渗透信号控制着多能干细胞中的染色质状态和命运转变 | McCreery, K. P. | N/A | Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells | |
| 通过田间试验欧洲网络的元分析，在春二棱大麦中发现了新的位点和候选基因 | Montardit-Tarda, F. | N/A | New loci and candidate genes in spring two-rowed barley detected through meta-analysis of a field trial European network | |
| 阿米巴虫属（Amoebophrya sp.）源自卡洛迪尼姆藻（Karlodinium veneficum）的核与线粒体基因组 | DeMontigny, W. | N/A | The Nuclear and Mitochondrial Genomes of Amoebophrya sp. ex Karlodinium veneficum | |
| Grb2磷酸化通过干扰凝聚物的组装，拮抗EGFR驱动的Ras激活。 | Phan, H. T. | N/A | Grb2 Phosphorylation Antagonizes EGFR-driven Ras Activation by Interfering with Condensate Assembly | |
| # BioRxiv 2024-09-05 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| ESCRT蛋白CHMP5通过调控内溶酶体-线粒体介导的细胞衰老来限制骨形成。 | Zhang, F. | N/A | The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence | |
| 个性化神经影像揭示了儿童兴趣对大脑语言处理的影响 | Olson, H. A. | N/A | Personalized Neuroimaging Reveals the Impact of Children's Interests on Language Processing in the Brain | |
| 免疫细胞利用间歇性的整合素介导的牵引力进行三维迁移 | Czerwinski, T. | N/A | Immune cells employ intermittent integrin-mediated traction forces for 3D migration | |
| 癌症相关成纤维细胞亚型调节肿瘤免疫微环境，并与皮肤癌恶性程度相关。 | Forsthuber, A. | N/A | Cancer associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy | |
| 三维变量分析揭示了人类天冬酰胺合成酶中控制氨传输的隐藏构象动力学 | Coricello, A. | N/A | 3D Variable Analysis Reveal a Hidden Conformational Dynamics Controlling Ammonia Transport in Human Asparagine Synthetase | |
| 人类工作记忆和长时记忆中的注意力集中：通过可分离过程带来的益处 | Gong, D. | N/A | Focusing attention in human working memory and long-term memory: benefits through dissociable processes | |
| 健康成人中人诺如病毒的宿内和宿间进化 | Ramani, S. | N/A | Intra- and Inter-host Evolution of Human Norovirus in Healthy Adults | |
| 昆虫变化：评论 | Gaume, L. | N/A | InsectChange: Comment | |
| 自噬限制了真菌在拟南芥根部中的定植 | Zecua-Ramirez, P. | N/A | Autophagy restricts fungal accommodation in the roots of Arabidopsis thaliana | |
| 通过亲和捕获的淋巴细胞冷冻电子断层扫描揭示的胞外纤维 | Engel, L. | N/A | Extracellular filaments revealed by affinity capture cryo-electron tomography of lymphocytes | |
| 利用全细胞模型和机器学习加速设计尺寸减小的埃希氏大肠杆菌基因组 | Gherman, I. M. | N/A | Accelerated design of Escherichia coli genomes with reduced size using a whole-cell model and machine learning | |
| 利用适应度景观建模和强化学习加速蛋白质工程 | Sun, H. | N/A | Accelerating protein engineering with fitness landscape modeling and reinforcement learning | |
| 一种“自杀性”BCG菌株在猕猴中提供了增强的免疫原性和对结核分枝杆菌的强大保护。 | Smith, A. A. | N/A | A "suicide" BCG strain provides enhanced immunogenicity and robust protection against Mycobacterium tuberculosis in macaques | |
| 生物传感器表征：从蛋白质组分角度出发的正式方法 | Arias Vaccari, N. | N/A | Biosensors Characterization: Formal methods from the Perspective of Proteome Fractions | |
| 免疫相关蛋白Serpina3n对大脑发育和髓鞘形成的可调控作用 | Zhu, M. | N/A | Dispensable regulation of brain development and myelination by the immune-related protein Serpina3n | |
| 与惊讶的沟通——新奇人类互动中目标信号的计算原理 | Buidze, T. | N/A | Communication with Surprise-Computational Principles of Goal Signaling in Novel Human Interactions | |
| 一线抗结核药物应激下耻垢分枝杆菌的遗传稳定性：评估其诱变潜能 | Molnar, D. | N/A | Genetic Stability of Mycobacterium smegmatis under the Stress of First-Line Antitubercular Agents: Assessing Mutagenic Potential | |
| 小鼠犁鼻器在单细胞分辨率下的分子、细胞和发育组织 | Hills, M. H. | N/A | Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal Organ at Single Cell Resolution | |
| 单细胞MALDI-MSI分析复制性衰老成纤维细胞模型中的脂质和蛋白质 | Sekera, E. R. | N/A | Single Cell MALDI-MSI Analysis of Lipids and Proteins within a Replicative Senescence Fibroblast Model | |
| 早期生活压力诱导的miR-708-5p调控小鼠情绪障碍相关的行为表型，并可能是双相情感障碍的潜在诊断生物标志物。 | Gilardi, C. | N/A | Early life stress-induced miR-708-5p regulates mood disorder-associated behavioural phenotypes in mice and is a potential diagnostic biomarker for bipolar disorder | |
| 使用AlphaFold预测PROTAC介导的蛋白质-蛋白质界面的挑战 | Pereira, G. P. | N/A | Challenges in predicting PROTAC-mediated Protein-Protein Interfaces with AlphaFold | |
| 成年小鼠中天然前体的动态追踪 | Liu, S. | N/A | Dynamic Tracking of Native Precursors in Adult Mice | |
| 细胞周期依赖性的P-bodies中mRNA定位 | SAFIEDDINE, A. | N/A | Cell cycle-dependent mRNA localization in P-bodies | |
| PIKFYVE抑制通过氨积累导致源自内体和溶酶体的空泡扩大 | Uwada, J. | N/A | PIKFYVE inhibition induces endosome- and lysosome-derived vacuole enlargement via ammonium accumulation | |
| 生态而非社会因素解释了头足类动物的大脑尺寸：我们需要一个新的模型来解释大脑进化的过程 | Basava, K. | N/A | Ecological not social factors explain brain size in cephalopods: we need a new model for the evolution of big brains | |
| 在化学定义的合成饮食中，纯化的纤维会破坏杂食性昆虫模型的肠道微生物群。 | Dockman, R. | N/A | Purified fibers in chemically defined synthetic diets destabilize the gut microbiome of an omnivorous insect model | |
| 脂多糖出口的动态基础由LptB2FGC提供 | Dajka, M. | N/A | Dynamic basis of lipopolysaccharide export by LptB2FGC | |
| 对Physcomitrella N端组学的快照揭示了细胞器蛋白质的N端甲基化 | Hoernstein, S. N. W. | N/A | A snapshot of the Physcomitrella N-terminome reveals N-terminal methylation of organellar proteins | |
| 工程化酿酒酵母以生产富含石榴酸的酵母生物质 | Wang, J. | N/A | Engineering Saccharomyces cerevisiae for the production of punicic acid-rich yeast biomass | |
| 通过泛线粒体基因组图谱揭示的真菌植物病原体中的频繁基因交换 | van Westerhoven, A. | N/A | Frequent genetic exchanges revealed by a pan-mitogenome graph of a fungal plant pathogen | |
| 1-甲基-4-苯基-1,2,3,6-四氢吡啶（MPTP）处理的成年斑马鱼作为帕金森病模型 | Bagwell, E. | N/A | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-Treated Adult Zebrafish as a Model for Parkinsons Disease | |
| 由PIM1激活的HIF-1组装了一个病理性的转录复合物和调控网络，驱动JAK2V617F骨髓增生性肿瘤疾病的发展。 | Kealy, D. | N/A | HIF-1 activated by PIM1 assembles a pathological transcription complex and regulon that drives JAK2V617F MPN disease | |
| 长读RNA测序揭示了等位基因特异性的N6-甲基腺苷修饰 | Park, D. | N/A | Long-read RNA sequencing reveals allele-specific N6-methyladenosine modifications | |
| 多模态MEG与微结构MRI研究人类海马场景网络 | Read, M.-L. | N/A | Multimodal MEG and microstructure-MRI investigations of the human hippocampal scene network | |
| P(all-atom)正在为蛋白质设计开辟新的道路 | Qu, W. | N/A | P(all-atom) Is Unlocking New Path For Protein Design | |
| 优化基于转录组的合成致死预测，以提高早期乳腺癌的精准肿瘤学：BC-SELECT | Kim, Y. | N/A | Optimizing transcriptome-based synthetic lethality predictions to improve precision oncology in early-stage breast cancer: BC-SELECT | |
| RBN-2397是一种PARP7抑制剂，与紫杉醇联合使用可协同抑制卵巢癌细胞的增殖和迁移。 | Spirtos, A. N. | N/A | RBN-2397, a PARP7 Inhibitor, Synergizes with Paclitaxel to Inhibit Proliferation and Migration of Ovarian Cancer Cells | |
| 晶体学中的自动晶体识别：直接方法与人工智能策略的比较 | Lages, C. F. | N/A | Automatic crystal identification for crystallography: a comparison between direct methods and artificial intelligence strategies | |
| 慢性间歇性饮酒会导致皮质-纹状体-边缘系统振荡出现性别特异性的紊乱。 | Hewitt, K. | N/A | Chronic intermittent alcohol yields sex-specific disruptions in cortical-striatal-limbic oscillations | |
| GPRC6A作为一种新型鲜味受体，通过鸟氨酸增强了味觉偏好 | Yamamoto, T. | N/A | GPRC6A as a novel kokumi receptor responsible for enhanced taste preferences by ornithine | |
| 在垒球运动中，经过针对性的感知认知训练后，击球技能多年持续提升 | Muraskin, J. | N/A | Multiyear Improvement In Batting Skills Following Targeted Perceptual Cognitive Training In Softball | |
| 质膜转运蛋白渐进性僵硬蛋白同源物（ANKH/Ankh）介导衰老相关的细胞外柠檬酸盐，并受DNA损伤、炎症和衰老的调控。 | James, E. N. | N/A | Plasma membrane transporter Progressive Ankylosis Protein Homolog (ANKH/Ankh) mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation and ageing | |
| 斑马鱼幼体数量感知的神经基础 | Luu, P. | N/A | Neural Basis of Number Sense in Larval Zebrafish | |
| 疟蚊复杂的群聚动力学源于简单且最小化的互动行为规则。 | Cribellier, A. | N/A | The complex swarming dynamics of malaria mosquitoes emerges from simple minimally-interactive behavioral rules | |
| 实验室观察显示，成年大黄蜂幼虫在夜间仍会继续发出叫声。 | FUJIOKA, H. | N/A | Laboratory observations reveal that mature Vespa mandarinia larvae continue calling at night | |
| 在老鼠视觉皮层中，视觉体验依赖的听觉和视觉可塑性 | Terra, H. | N/A | Visual experience-dependent auditory and visual plasticity in the mouse visual cortex | |
| 全脑电路在自闭症斑马鱼模型中改变听觉习惯化的作用。 | Wilde, M. | N/A | Brain-wide circuitry underlying altered auditory habituation in zebrafish models of autism. | |
| 海马神经突起发育变化与调节低θ振荡相关基因的表达共定位 | Kember, J. | N/A | Developmental changes in hippocampal neurite colocalize with the expression of genes involved in modulating low-theta oscillations | |
| 右侧尾状核体积与注意缺陷/多动障碍（ADHD）儿童的执行功能 | Hai, T. | N/A | Right Caudate Volume and Executive Functions in Children with Attention-Deficit/Hyperactivity Disorder (ADHD) | |
| 人类丘脑内侧背侧核和室旁核中保守的细胞类型梯度 | Schulmann, A. | N/A | A conserved cell-type gradient across the human mediodorsal and paraventricular thalamus | |
| 灵长类动物外侧前额叶皮层神经元中的脉冲频率适应是由内在特性和电路动态相互作用的结果。 | Koch, N. A. | N/A | Spike frequency adaptation in primate lateral prefrontal cortex neurons results from interplay between intrinsic properties and circuit dynamics | |
| 一棵根深蒂固的真核生物树揭示了它们的挖掘祖先起源。 | Williamson, K. | N/A | A robustly rooted tree of eukaryotes reveals their excavate ancestry. | |
| 从聚合的染色质可及性数据推断基因型揭示了遗传调控机制 | Wenz, B. M. | N/A | Genotype inference from aggregated chromatin accessibility data reveals genetic regulatory mechanisms | |
| 孕期接触丙戊酸会导致大鼠皮质和海马神经元结构和功能的性别特异性改变。 | Williams, O. O. F. | N/A | Prenatal exposure to valproic acid induces sex-specific alterations in cortical and hippocampal neuronal structure and function in rats | |
| Arc/Arg3.1 结合核多聚腺苷酸结合蛋白 RRM，并调控神经元活动依赖性的核斑点形成 | Kanhema, T. | N/A | Arc/Arg3.1 binds the nuclear polyadenylate-binding protein RRM and regulates neuronal activity-dependent formation of nuclear speckles | |
| 在刺虫精子发生过程中重组、X染色体失活以及着丝粒蛋白的动态变化 | Toubiana, W. | N/A | Dynamics of recombination, X inactivation and centromere proteins during stick insect spermatogenesis | |
| 在秀丽隐杆线虫的受精囊中，肌动蛋白细胞骨架和顶端细胞连接处的张力受到受精囊解剖结构、排卵状态以及肌球蛋白激活的影响。 | Sadeghian, F. | N/A | Tensions on the actin cytoskeleton and apical cell junctions in the C. elegans spermatheca are influenced by spermathecal anatomy, ovulation state and activation of myosin | |
| 化学伴侣——山梨醇可纠正罗伯茨突变体的粘附和翻译缺陷 | BOSE, T. | N/A | Chemical chaperone - sorbitol corrects cohesion and translational defects in the Roberts mutant | |
| Piezo1的机械感应通过PP2A-Akt轴调节牙周炎中的破骨细胞分化 | Shindo, S. | N/A | Mechanosensing by Piezo1 regulates osteoclast differentiation via PP2A-Akt axis in periodontitis | |
| Meckel-Gruber综合征蛋白TMEM67通过ADAMTS9蛋白酶解切割生成的两种功能形式介导Wnt信号传导和纤毛发生。 | Ahmed, M. | N/A | Two functional forms of the Meckel-Gruber syndrome protein TMEM67 generated by proteolytic cleavage by ADAMTS9 mediate Wnt signaling and ciliogenesis | |
| 缝隙连接蛋白1与Hippo通路在恶性黑色素瘤中的相互作用 | Sayedyahossein, S. | N/A | Pannexin 1 crosstalk with the Hippo pathway in malignant melanoma | |
| Zbtb38通过转录调控XIAP表达来抑制细胞凋亡。 | Matsuda, E. | N/A | Zbtb38 inhibits apoptosis by transcriptionally regulating XIAP expression | |
| 银屑病样炎症诱导人角质形成细胞和成纤维细胞的线粒体功能和结构改变 | Kulkoviene, G. | N/A | Psoriasis-like inflammation induces mitochondrial function and structure changes in human keratinocytes and fibroblasts | |
| RCC1 耗竭导致蛋白质运输缺陷和微核破裂 | Zych, M. G. | N/A | RCC1 depletion drives protein transport defects and rupture in micronuclei | |
| 细胞外囊泡的生物活性和潜在的临床应用价值取决于间充质基质细胞的克隆亚型。 | Ioannou, S. | N/A | Extracellular vesicle bioactivity and potential clinical utility is determined by mesenchymal stromal cell clonal subtype | |
| 线粒体移植：一种治疗肝缺血/再灌注损伤的新型疗法 | Mukkala, A. N. | N/A | Mitochondrial transplantation: a novel therapy for liver ischemia/reperfusion injury | |
| 巨轴突神经病变中突变的Gigaxonin与TDP-43及其他RNA结合蛋白相互作用 | Phillips, C. L. | N/A | Gigaxonin, mutated in Giant Axonal Neuropathy, interacts with TDP-43 and other RNA binding proteins | |
| 培养条件差异性调控气管支气管基底干细胞的炎症微环境和细胞表型 | Murthy, S. | N/A | Culture Conditions Differentially Regulate the Inflammatory Niche and Cellular Phenotype of Tracheo-Bronchial Basal Stem Cells | |
| RTN4IP1对于线粒体复合物I组装和辅酶Q生物合成的最后阶段至关重要。 | Olahova, M. | N/A | RTN4IP1 is essential for the final stages of mitochondrial complex I assembly and coenzyme Q biosynthesis | |
| MLX的磷酸化作用稳定了ChREBP-MLX异四聚体在串联E-box上的结合，从而调控碳水化合物和脂质代谢。 | Shimobayashi, M. | N/A | MLX phosphorylation stabilizes the ChREBP-MLX heterotetramer on tandem E-boxes to control carbohydrate and lipid metabolism | |
| MLX磷酸化稳定了ChREBP-MLX异源四聚体在串联E-box上的结合，从而调控碳水化合物和脂质代谢。 | Cadena del Castillo, C. | N/A | MLX phosphorylation stabilizes the ChREBP-MLX heterotetramer on tandem E-boxes to control carbohydrate and lipid metabolism | |
| 脂肪酸在膜脂和储存脂质之间的分配调控内质网膜的扩张。 | Lysyganicz, P. K. | N/A | The partitioning of fatty acids between membrane and storage lipids controls ER membrane expansion. | |
| 果蝇运动决策的时空动态 | Lebovich, L. | N/A | Spatiotemporal dynamics of locomotor decisions in Drosophila melanogaster | |
| 卫星胶质细胞调节背根神经节中本体感受神经元的活动 | Rabah, Y. | N/A | Satellite glial cells modulate proprioceptive neuron activity in dorsal root ganglia | |
| 水通道蛋白-4在嗅上皮中的表达和定位调节了气味诱发的反应和嗅觉驱动的行为 | Lobraico, D. | N/A | The Aquaporin-4 expression and localization in the olfactory epithelium modulate the odorant-evoked responses and olfactory driven behavior | |
| Hox基因，腹部A，控制果蝇中枢神经系统发育过程中神经干细胞的及时有丝分裂进入及其生长。 | ARYA, R. | N/A | The Hox Gene, abdominal A controls timely mitotic entry of neural stem cell and their growth during CNS development in Drosophila | |
| 从组织到亚细胞层面：通过成像人类精密切割肺切片（PCLS）以深入了解大流行细菌或病毒感染 | Eymieux, S. | N/A | From tissue to subcellular level : imaging human precision-cut lung slices (PCLS) to gain insight into pandemic bacterial or viral infections | |
| 阿尔茨海默病脑源性tau聚集物的特性定义了人类星形胶质细胞对tau的加工。 | Reid, M. J. | N/A | Properties of Alzheimers disease brain-derived tau aggregates define tau processing by human astrocytes. | |
| 单次检测微尺度触觉特征 | Reschechtko, S. | N/A | Single-shot detection of microscale tactile features | |
| 使用可调水凝胶解耦触觉湿润感知的冷暖与柔软度 | Becerra, L. L. | N/A | Decoupling Coldness and Softness in Tactile Wetness Perception Using Tunable Hydrogels | |
| 牙龈卟啉单胞菌外膜囊泡改变了胚胎小鼠大脑中的神经元结构和Tau蛋白磷酸化 | Bradley, A. | N/A | Porphyromonas gingivalis outer membrane vesicles alter neuronal architecture and Tau phosphorylation in the embryonic mouse brain | |
| 启动线索的感官背景会调节与动作目标相关的神经表征 | Kreter, N. | N/A | Sensory context of initiation-cue modulates action goal-relevant neural representations | |
| 通过使用FluidFM挑选和放置神经球体，构建具有多种细胞类型的定义明确的神经网络 | Vulic, K. | N/A | Constructing well-defined neural networks of multiple cell types by picking and placing of neuronal spheroids using FluidFM | |
| 脑-身互动影响从心智游移到对当前思维意识的状态转变 | Shinagawa, K. | N/A | Brain-Body Interactions Influence the Transition from Mind Wandering to Awareness of Ongoing Thought | |
| 与内在电导相比，电路功能对突触电导的变化更为鲁棒。 | Fournier, Z. | N/A | Circuit function is more robust to changes in synaptic than intrinsic conductances | |
| 双位点经颅交流电刺激对血氧水平依赖信号的即时调制在整个大脑中传播 | Hiromitsu, K. | N/A | Immediate Modulation of the Blood Oxygenation Level-Dependent Signals by Dual-Site Transcranial Alternating Current Stimulation Propagates Across the Whole Brain | |
| 基于他人学习偏好的政策塑造解释了在社会观察下的冒险决策行为 | Seon, H. | N/A | Policy shaping based on the learned preferences of others accounts for risky decision-making under social observation | |
| 全狨猴大脑的串行双光子断层扫描成像用于神经解剖学分析 | Watakabe, A. | N/A | Serial Two-Photon Tomography Imaging of the whole marmoset brain for neuroanatomical analyses | |
| 一种灵活的高精度光声视网膜假体 | Leong, A. | N/A | A flexible high-precision photoacoustic retinal prosthesis | |
| 听觉伪词的光谱-时间特征和语音特征对多种声音象征映射的差异性贡献 | Lacey, S. | N/A | DIFFERENTIAL CONTRIBUTIONS OF THE SPECTRO-TEMPORAL AND VOCAL CHARACTERISTICS OF AUDITORY PSEUDOWORDS TO MULTIPLE SOUND-SYMBOLIC MAPPINGS | |
| 在小鼠中，周围炎症伴随有脑部血流减少。 | Kazeem, A. | N/A | Peripheral Inflammation is accompanied by Cerebral Hypoperfusion in Mice | |
| 催产素通过道德框架挽救了特定情境下的超利他偏好 | Zhang, H. | N/A | Oxytocin salvages context-specific hyperaltruistic preference through moral framing | |
| 计算机视觉引导下快速精准的啮齿动物颅内显微手术自动化 | Navabi, Z. S. | N/A | Computer vision guided rapid and precise automated cranial microsurgeries in rodents | |
| 在β冠状病毒家族中，刺突S2域N-糖基化的保守作用 | Yang, Q. | N/A | Conserved role of spike S2 domain N-glycosylation across beta-coronavirus family | |
| 英国诺福克地区2020年3月至2022年12月SARS-CoV-2的基因组流行病学 | Hayles, E. H. | N/A | Genomic Epidemiology of SARS-CoV-2 in Norfolk, UK, March 2020 - December 2022 | |
| 结核分枝杆菌必需转运蛋白A的结构与抑制机制 | Khandelwal, N. K. | N/A | Structure and inhibition mechanisms of Mycobacterium tuberculosis essential transporterefflux protein A | |
| Nsp1在DNA发夹处阻碍DNA聚合酶α的进程 | Baranovskiy, A. G. | N/A | Nsp1 stalls DNA Polymerase alpha at DNA hairpins | |
| SARS-CoV-2的主要蛋白酶（Mpro）通过激活凝血因子VII和FXII，在体外引发血浆凝固。 | Pagotto, A. | N/A | The Main protease (Mpro) from SARS-CoV-2 triggers plasma clotting in vitro by activating coagulation factors VII and FXII | |
| 六种铜绿假单胞菌噬菌体的全基因组序列，旨在用于研究和治疗 | Rimon, A. | N/A | Complete Genome Sequence of Six Pseudomonas aeruginosa Bacteriophages aim for research and treatments | |
| 转录终止和抗终止对于整合接合元件Tn916的适应性和功能至关重要。 | Wirachman, E. S. | N/A | Transcription termination and antitermination are critical for the fitness and function of the integrative and conjugative element Tn916 | |
| CLIC/GEEC途径调控HIV-1感染的巨噬细胞中颗粒的内吞作用及病毒包含体（VCC）的形成 | Candor, K. | N/A | The CLIC/GEEC pathway regulates particle endocytosis and formation of the virus-containing compartment (VCC) in HIV-1-infected macrophages | |
| 绘制棒状细菌细胞表面的超微结构拓扑图 | Isbilir, B. | N/A | Mapping the ultrastructural topology of the corynebacterial cell surface | |
| 谷氨酸棒杆菌PS2 S层的冷冻电镜结构与极性组装 | Sogues, A. | N/A | Cryo-EM structure and polar assembly of the PS2 S-layer of Corynebacterium glutamicum | |
| Lachancea thermotolerans中亚群特异性基因表达揭示了葡萄酒发酵过程中不同的代谢适应 | VICENTE, J. | N/A | Subpopulation-specific gene expression in Lachancea thermotolerans uncovers distinct metabolic adaptations to wine fermentation | |
| 应用条形码测序技术提高恶性疟原虫遗传筛选的通量和复杂性 | Muwhezi, A. | N/A | Application of barcode sequencing to increase the throughput and complexity of Plasmodium falciparum genetic screening | |
| 磷酸铁试剂法：一种用于研究植物根部细菌产生的氧化还原活性代谢物的工具 | Giacalone, D. | N/A | The phospho-ferrozine assay: A tool to study bacterial redox-active metabolites produced at the plant root | |
| 与时间赛跑：描述奇瓦瓦沙漠中极度濒危的微生物绿洲的微生物多样性 | Rodriguez-Cruz, U. E. | N/A | Running against the clock: describing microbial diversity in an extremely endangered microbial oasis in the Chihuahuan desert | |
| 志贺氏菌效应蛋白IpaH1.4促进RNF213的降解，并保护细胞质中的细菌免受干扰素诱导的泛素化作用。 | Saavedra Sanchez, L. | N/A | The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation | |
| 抗寄生虫药物塞拉菌素在耻垢分枝杆菌中产生抗药性的可能性不大，且取决于细胞壁的完整性。 | Ezquerra-Aznarez, J. M. | N/A | Emergence of resistance to the antiparasitic selamectin in Mycobacterium smegmatis is improbable and contingent on cell wall integrity | |
| PIP2促进CD43、PSGL-1和CD44整合入新生的HIV-1颗粒中。 | Cardoso, R. d. S. | N/A | PIP2 promotes the incorporation of CD43, PSGL-1 and CD44 into nascent HIV-1 particles | |
| 评估选定植物提取物对采后白山药腐烂的抗菌潜力 | Ibuot, A. A. | N/A | Assessing the Antimicrobial potentials of selected Plant Extracts against Post Harvest White Yam Rot | |
| 针对特定激酶底物的干预措施可缓解由克罗恩病相关LRRK2-N2081D变异体引发的结肠炎严重程度增加 | Heaton, G. R. | N/A | Targeting Specific Kinase Substrates Rescues Increased Colitis Severity Induced by the Crohn's Disease-Linked LRRK2-N2081D Variant | |
| 线粒体拓扑异构酶I（Top1MT）可预防小鼠代谢功能障碍相关脂肪性肝炎（MASH）的发生。 | Baechler, S. A. | N/A | Mitochondrial topoisomerase I (Top1MT) prevents the onset of metabolic dysfunction-associated steatohepatitis (MASH) in mice | |
| 一个南美洲库蚊（双翅目：蚊科）的DNA条形码库，并描述了亚属Melanoconion中的两种隐秘物种。 | Talaga, S. | N/A | A DNA barcode library for Culex mosquitoes (Diptera: Culicidae) of South America with the description of two cryptic species of subgenus Melanoconion | |
| JN.1衍生的LB.1、KP.2.3、KP.3和KP.3.1.1亚型的中和与稳定性 | Li, P. | N/A | Neutralization and Stability of JN.1-derived LB.1, KP.2.3, KP.3 and KP.3.1.1 Subvariants | |
| 利用长读长技术对澳大利亚高山石龙子（Bassiana duperreyi）进行基因组组装与注释 | Hanrahan, B. J. | N/A | A genome assembly and annotation for the Australian alpine skink Bassiana duperreyi using long-read technologies | |
| 对MKP5双特异性磷酸酶的别构调控的动态和结构见解 | Skeens, E. | N/A | Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase | |
| 基于结构的PROTAC设计用于降解可溶性环氧化物水解酶 | Schoenfeld, J. | N/A | STRUCTURE-BASED DESIGN OF PROTACS FOR THE DEGRADATION OF SOLUBLE EPOXIDE HYDROLASE | |
| 驱动蛋白-8通过将其近端尾部结构域折叠成一个紧凑的螺旋束而形成二聚体。 | Allingham, J. S. | N/A | Kinesin-8 motors dimerize by folding their proximal tail domain into a compact helical bundle | |
| CRISPR-Cas9靶向链切割通过抑制复制提供了噬菌体抗性。 | Nguyen, G. T. | N/A | CRISPR-Cas9 target-strand nicking provides phage resistance by inhibiting replication | |
| 基于人工智能的发现与低温电子显微镜结构解析：一种KATP通道药物伴侣蛋白 | Elsheikh, A. | N/A | AI-Based Discovery and CryoEM Structural Elucidation of a KATP Channel Pharmacochaperone | |
| 通过计算识别能够增加哺乳动物细胞中合成回路基因表达的小分子 | Pisani, M. | N/A | Computational identification of small molecules for increased gene expression by synthetic circuits in mammalian cells | |
| CryptKeeper：一种用于减少细菌中意外基因表达的负面设计工具 | Roots, C. T. | N/A | CryptKeeper: a negative design tool for reducing unintentional gene expression in bacteria | |
| 内源性逆转录病毒通过激活MARCO介导的炎症反应来阻止逆转录病毒感染 | Xuming, H. | N/A | Endogenous retroviruses activate MARCO-mediated inflammatory response to block retroviral infection | |
| SARS-CoV-2 Nsp15 对抗 cGAS-STING 介导的抗病毒先天免疫反应 | Lee, B. | N/A | SARS-CoV-2 Nsp15 antagonizes the cGAS-STING-mediated antiviral innate immune responses | |
| 工业和农业化学品对人类肠道细菌的非预期作用 | Lindell, A. E. | N/A | Off-purpose activity of industrial and agricultural chemicals against human gut bacteria | |
| 转录组规模分析揭示了细菌RNA伴侣Hfq疏水核心中对小调控RNA稳定性至关重要的保守残基 | McQuail, J. | N/A | Transcriptome-scale analysis uncovers conserved residues in the hydrophobic core of the bacterial RNA chaperone Hfq required for small regulatory RNA stability | |
| 环境抗生素抗性组：植物根系发育早期阶段HAE-1外排泵的选择 | Simenel, O. | N/A | Environmental antibiotic resistome: selection of HAE-1 efflux pumps in early stages of plant root development | |
| ADAR1 调控 ZBP1 介导的 PANoptosis 和心脏移植排斥反应 | Lu, H. | N/A | ADAR1 orchestrates the ZBP1-mediated PANoptosis and heart transplant rejection | |
| 红珠之咒：由光毒性引起的成纤维细胞特异性珍珠项链线粒体表型 | Hemel, I. M. | N/A | The curse of the red pearl: a fibroblast specific pearl-necklace mitochondrial phenotype caused by phototoxicity | |
| 使用MS Annika 3.0进行蛋白质组范围的不可切割交联鉴定揭示了秀丽隐杆线虫Box C/D复合物的结构 | Birklbauer, M. J. | N/A | Proteome-wide non-cleavable crosslink identification with MS Annika 3.0 reveals the structure of the C. elegans Box C/D complex | |
| 哺乳动物与斑胸草雀之间突变和重组参数的保守性 | Prentout, D. | N/A | Conservation of mutation and recombination parameters between mammals and zebra finch | |
| 共享的遗传架构将能量代谢、行为和抗饥饿能力沿着力量-耐力轴联系在一起 | Erkosar, B. | N/A | Shared genetic architecture links energy metabolism, behavior and starvation resistance along a power-endurance axis | |
| 蜜蜂卵的成分随季节变化，并在母体急性病毒感染后发生变化 | Chapman, A. | N/A | Honey bee egg composition changes seasonally and after acute maternal virus infection | |
| 控制蜜蜂（Apis mellifera）蜂王生长的社会和营养因素 | Kama, O. | N/A | The Social and Nutritional Factors Controlling the Growth of Honey Bee (Apis mellifera) Queens | |
| 非线性树突整合支持单个神经元中的上下状态 | Quaresima, A. | N/A | Nonlinear dendritic integration supports Up-Down states in single neurons | |
| 利用TMS-EEG研究在反应性和前瞻性运动抑制过程中GABA能抑制与谷氨酸能兴奋之间的复杂相互作用 | Zhu, T. | N/A | Using TMS-EEG to study the intricate interplay between GABAergic inhibition and glutamatergic excitation during reactive and proactive motor inhibition | |
| 海马体神经元活动与行动计划相一致。 | Zutshi, I. | N/A | Hippocampal neuronal activity is aligned with action plans | |
| 统计学习过程中期望的可分离动态效应。 | McDermott, H. H. | N/A | Dissociable dynamic effects of expectation during statistical learning. | |
| 下丘脑-脑干回路控制着将安全置于基本需求之上的优先级。 | Krauth, N. | N/A | A hypothalamus-brainstem circuit governs the prioritization of safety over essential needs | |
| 使用微图案化的玻璃上突触前模型解析突触前肌动蛋白的纳米级结构 | Tumminia, S. | N/A | Deciphering the nanoscale architecture of presynaptic actin using a micropatterned presynapse-on-glass model | |
| 水田鼠的饮食是否与解释种群波动的植物假说一致？ | Pinot, A. | N/A | Is water vole diet consistent with the plant hypothesis for explaining population fluctuations? | |
| 喜马拉雅地区濒危药用植物刺檗（Berberis lycium Royle）沿海拔梯度的植物-传粉者相互作用 | Anjum, N. | N/A | Plant-Pollinator Interactions along the Altitudinal Gradient in Berberis lycium Royle: An Endangered Medicinal Plant Species of the Himalayan Region | |
| 埃及伊蚊入侵动态变化及其对秘鲁亚马逊地区农村社区的媒介传播疾病风险 | Fikrig, K. M. | N/A | Changing dynamics of Aedes aegypti invasion and vector-borne disease risk for rural communities in the Peruvian Amazon | |
| 公共基因组数据库中高度受限基因的独特特征 | Agrawal, P. | N/A | Unique Signatures of Highly Constrained Genes Across Publicly Available Genomic Databases | |
| # BioRxiv 2024-09-04 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 染色质阅读器Dido3是调控B细胞分化基因网络的调节因子。 | Gutierrez del Burgo, F. | N/A | The chromatin reader Dido3 is a regulator of the gene network that controls B cell differentiation | |
| 黄矢车菊（Centaurea solstitialis）的染色体规模参考基因组和基于RAD的遗传图谱揭示了与入侵性状相关的潜在结构变异和数量性状位点（QTLs）。 | Reatini, B. | N/A | Chromosome-scale reference genome and RAD-based genetic map of yellow starthistle (Centaurea solstitialis) reveal putative structural variation and QTLs associated with invader traits | |
| Shewanella fidelis 3313 噬菌体调控其运动性和生物膜形成：对强壮海鞘肠道定殖动态的影响 | Natarajan, O. | N/A | Prophage regulation of Shewanella fidelis 3313 motility and biofilm formation: implications for gut colonization dynamics in Ciona robusta | |
| 蒙古沙鼠家族特定发声用法的无监督发现 | Peterson, R. E. | N/A | Unsupervised discovery of family specific vocal usage in the Mongolian gerbil | |
| 动作电位的消失会诱导神经元之间的电耦合 | Schloetter, M. | N/A | Annihilation of action potentials induces electrical coupling between neurons | |
| 通过灵长类抓握回路中与姿势相关的活动，对手部假肢进行精确的神经控制 | Agudelo-Toro, A. | N/A | Accurate neural control of a hand prosthesis by posture-related activity in the primate grasping circuit | |
| M3NetFlow：一种用于综合多组学数据分析的新型多尺度多跳图AI模型 | Zhang, H. | N/A | M3NetFlow: A novel multi-scale multi-hop graph AI model for integrative multi-omic data analysis | |
| GluK1海人藻受体中第9外显子剪接插入的功能意义 | Dhingra, S. | N/A | Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors | |
| PARP14/TARG1调控的RACK1 MARylation循环驱动卵巢癌细胞中的应激颗粒动态变化 | Challa, S. | N/A | A PARP14/TARG1-Regulated RACK1 MARylation Cycle Drives Stress Granule Dynamics in Ovarian Cancer Cells | |
| 广布性浮游植物巴氏藻（Bathycoccus）的生物学和基因组资源：对遗传多样性和主要结构变异的洞察 | Dennu, L. | N/A | Biological and genomic resources for the cosmopolitan phytoplankton Bathycoccus: Insights into genetic diversity and major structural variations | |
| dact1/2调控非经典Wnt信号传导和钙蛋白酶8在胚胎趋同延伸和颅面形态发生中的遗传需求 | Carroll, S. H. | N/A | Genetic requirement of dact1/2 to regulate noncanonical Wnt signaling and calpain 8 during embryonic convergent extension and craniofacial morphogenesis | |
| 人类中具有疾病表型的新进化基因揭示了由适应性创新和性选择塑造的功能富集模式。 | Chen, J. | N/A | Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection. | |
| 电子自旋极化与电荷动力学在蛋白质功能中的作用 | Vyas, P. | N/A | The Role of Electron Spin-Polarizability and Charge Dynamics in Protein Function | |
| 欧亚小鳟（鲤科：Phoxinus phoxinus）染色体水平、单倍型解析的基因组组装与注释提供了单倍型多样性的证据。 | Oriowo, T. O. | N/A | A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae: Phoxinus phoxinus) provide evidence of haplotype diversity | |
| 双酚A的质子转移对于激活核外启动的雌激素受体信号传导是必需的。 | Medina-Gali, R. M. | N/A | PROTON TRANSFER FROM BISPHENOL-A IS REQUIRED TO ACTIVATE EXTRANUCLEAR-INITIATED ESTROGEN RECEPTOR SIGNALING | |
| 可解释的多模态机器学习（IMML）框架揭示了远端感觉运动性多发性神经病变的病理特征。 | Nguyen, P. B. | N/A | The Interpretable Multimodal Machine Learning (IMML) framework reveals pathological signatures of distal sensorimotor polyneuropathy | |
| 药物适应性癌细胞系中的抗药性模式反映了临床肿瘤中复杂的进化过程。 | Grimsley, H. E. | N/A | Resistance patterns in drug-adapted cancer cell lines reflect complex evolution in clinical tumors | |
| 干扰抑制仅在视网膜坐标中起作用。 | Ilksoy, Y. A. | N/A | Distractor suppression operates exclusively in retinotopic coordinates | |
| 抑制性神经元中神经纤毛蛋白-2表达失调损害海马回路发育，导致自闭症-癫痫表型 | Subramanian, D. | N/A | Dysregulation of Neuropilin-2 Expression in Inhibitory Neurons Impairs Hippocampal Circuit Development Leading to Autism-Epilepsy Phenotype | |
| 通过选择性繁殖的小鼠肠道微生物群中的罗伊氏乳杆菌增强了驯服性 | Biswa, B. B. | N/A | Enhanced tameness by Limosilactobacillus reuteri from gut microbiota of selectively bred mice | |
| 2P-NucTag：用于功能性识别皮层神经元分子分析的按需光标记技术 | Shi, J. | N/A | 2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons | |
| 通过神经网络收敛揭示的视觉人类前额叶激活的文本相关功能 | Shoham, A. | N/A | Text-related functionality of visual human pre-frontal activations revealed through neural network convergence | |
| 当前的基因组深度学习架构在草类物种间具有泛化能力，但在等位基因方面不具备泛化能力。 | Wrightsman, T. | N/A | Current genomic deep learning architectures generalize across grass species but not alleles | |
| 整合脊椎动物神经管中空间和时间模式化的顺式调控逻辑 | Zhang, I. | N/A | The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube | |
| 母体肥胖可能通过增加DNMTs（DNA甲基转移酶）导致卵母细胞基因组过度甲基化，从而干扰后代的代谢。 | Chao, S. | N/A | Maternal obesity may disrupt offspring metabolism by inducing oocyte genome hyper-methylation via increased DNMTs | |
| 通过大型语言模型预测TET和DNMT3敲除突变体中的差异甲基化胞嘧啶 | sereshki, s. | N/A | Predicting Differentially Methylated Cytosines in TET and DNMT3 Knockout Mutants via a Large Language Model | |
| 抗体依赖性增强在DENV感染的Wistar大鼠中的作用，作为登革热小鼠模型 | Wihanto, L. | N/A | Role of antibody-dependent enhancement in DENV-infected Wistar rats as a dengue murine model | |
| 修正关系估计中的模型误设 | Jewett, E. M. | N/A | Correcting model misspecification in relationship estimates | |
| 脂肪细胞中的同源域转录因子与产热作用：对人类UCP1的物种特异性及保守调控元件的见解 | B. Toth, B. | N/A | Homeodomain transcription factors in adipocyte thermogenesis: insights into the species-specific and conserved regulatory elements of human UCP1 | |
| 全基因组条件性降解标签文库在功能基因组学中的应用 | Gameiro, E. | N/A | Genome-wide conditional degron libraries for functional genomics | |
| 一种高效预测自然物体感知相似性的高通量方法 | Kaniuth, P. | N/A | A high-throughput approach for the efficient prediction of perceived similarity of natural objects | |
| 酒精通过刺激AMPK介导的TORC1、p70/S6K和核糖体生物合成的抑制，诱导神经嵴中p53介导的细胞凋亡。 | Huang, Y. | N/A | Alcohol induces p53-mediated apoptosis in neural crest by stimulating the AMPK-mediated suppression of TORC1, p70/S6K, and ribosomal biogenesis. | |
| 在社会变形虫Dictyostelium discoideum中，支配等级是线性的但较为浅显。 | Broersma, C. M. E. | N/A | Dominance hierarchies are linear but shallow in the social amoeba Dictyostelium discoideum. | |
| 一个表示静息动作电位尖峰序列的数学序列 | Keum, D. | N/A | A Mathematical Sequence Representing Tonic Action Potential Spike Trains | |
| 食肉真菌少孢节丛孢的捕食装置是一种表型系统，用于分离热诱导的过量铁 | Zhou, J. | N/A | Trapping Devices of Carnivorous fungus Arthrobotrys oligospora is a Phenotypic System for Separating Thermally-Induced Excess Irons | |
| 纺织结构自动化模型发现：经编面料的独特力学特征 | McCulloch, J. A. | N/A | Automated model discovery for textile structures:The unique mechanical signature of warp knitted fabrics | |
| 一氧化碳驱动的生物乙醇生产通过依赖钨的催化剂进行。 | Lemaire, O. N. | N/A | Carbon monoxide-driven bioethanol production operates via a tungsten-dependent catalyst | |
| 非周期性和振荡系统构成了人类领域一般认知的基础 | Lu, R. | N/A | Aperiodic and oscillatory systems underpinning human domain-general cognition | |
| 用于斑马鱼异种移植模型的自动化微量注射技术 | Ding, Y. | N/A | Automated microinjection for zebrafish xenograft models | |
| 非洲慈鲷（Astatotilapia burtoni）的面部和体色与其社会等级有关。 | Peros, M. | N/A | Facial and body colouration are linked to social rank in the African cichlid, Astatotilapia burtoni | |
| 葡萄糖激酶活性控制着β细胞的亚群，这些亚群交替主导胰岛Ca²⁺振荡。 | Jin, E. | N/A | Glucokinase activity controls subpopulations of β-cells that alternately lead islet Ca2+ oscillations | |
| 穴样蛋白组装体将一个双层叶片的脂质排出，以组织和弯曲膜结构。 | Doktorova, M. | N/A | Caveolin assemblies displace one bilayer leaflet to organize and bend membranes | |
| 乳腺癌基因表达的综合元分析 | Nwosu, I. O. | N/A | A Comprehensive Meta-Analysis of Breast Cancer Gene Expression | |
| 在乙醇-CPP中追求再巩固：不同条件下的记忆再激活并未引发记忆的不稳定 | Zacouteguy Boos, F. | N/A | Pursuing reconsolidation in ethanol-CPP: memory reactivation in different conditions did not trigger destabilization | |
| 远端超级增强子驱动癌细胞中异常的CXCL13表达，通过CXCR5-CXCL13轴促进生长和p53失调 | Gothwal, S. K. | N/A | Distal super-enhancer drives aberrant CXCL13 expression in Cancer cells driving growth and p53 dysregulation via CXCR5-CXCL13 axis | |
| 人工自然杀伤细胞模拟系统设计，旨在靶向肿瘤细胞 | Chugh, V. | N/A | Design of an Artificial Natural Killer Cell Mimicking System to Target Tumour Cells | |
| 多感官方法在心理意象中的应用：ALE元分析比较运动、视觉和听觉意象 | Van Caenegem, E. E. | N/A | Multisensory approach in Mental Imagery: ALE meta-analyses comparing Motor, Visual and Auditory Imagery | |
| 深度对比学习实现了全基因组的虚拟筛选 | Jia, Y. | N/A | Deep contrastive learning enables genome-wide virtual screening | |
| 一种利用计算机视觉和DNA条形码技术相结合的无脊椎动物生物监测方法 | Blair, J. D. | N/A | A hybrid approach to invertebrate biomonitoring using computer vision and DNA metabarcoding | |
| 钠离子泄漏通道NALCN受到神经元SNARE复合体蛋白的调控。 | Usher, S. G. | N/A | The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins | |
| 单细胞多组学揭示了糖原代谢差异，这些差异是物种特异性发育速度的基础 | de la Porte, A. | N/A | Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development | |
| 活体成像与药代动力学：经皮注射的超声与X射线可成像的温度敏感水凝胶负载多柔比星与游离药物在猪体内的比较 | Delgado, J. F. | N/A | In vivo Imaging and Pharmacokinetics of Percutaneously Injected Ultrasound and X-ray Imageable Thermosensitive Hydrogel loaded with Doxorubicin versus Free Drug in Swine | |
| 驱动哺乳动物脊髓内运动神经元特异性病毒载荷表达的顺式调控元件 | Nagy, M. A. | N/A | Cis-regulatory elements driving motor neuron-restricted viral payload expression within the mammalian spinal cord | |
| 使用CRISPR-CAS9介导的LACZ基因编辑优化以马铃薯皮为葡萄糖源的工程大肠杆菌中脂肪酶的生产与特性分析 | Minari, J. B. | N/A | CRISPR-CAS9 MEDIATED EDITING OF THE LACZ GENE FOR OPTIMIZING LIPASE PRODUCTION AND CHARACTERIZATION IN ENGINEERED ESCHERICHIA COLI USING POTATO PEEL AS A GLUCOSE SOURCE | |
| 关于微生物活动在养分循环和转化中的作用及其对土壤肥力和作物生产力的影响的系统综述 | Zeleke, T. B. | N/A | Systematic Review on the Role of Microbial Activities on Nutrient Cycling and Transformation Implication for Soil Fertility and Crop Productivity | |
| IgSeqR：一种从非选择性RNA测序数据中识别、组装和表征全长肿瘤免疫球蛋白转录本的协议 | Bryant, D. | N/A | IgSeqR: a protocol for the identification, assembly, and characterization of full-length tumor Immunoglobulin transcripts from unselected RNA sequencing data | |
| 时间基因组动力学塑造多发性骨髓瘤的临床轨迹 | MAURA, F. | N/A | Temporal Genomic Dynamics Shape Clinical Trajectory in Multiple Myeloma | |
| 一项多维度的泛癌分析揭示了CDKN1A作为免疫学和预后生物标志物的作用 | Shi, L. | N/A | A multidimensional Pan-cancer analysis of CDKN1A identifies CDKN1A as an Immunological and Prognostic Biomarker | |
| 视觉注意对阿拉伯字母识别及阅读习得的影响 | Ghandour, A. | N/A | The influence of visual attention on letter recognition and reading acquisition in Arabic | |
| 音乐训练并不增强听觉系统早期阶段的神经声音编码：一项大规模多中心研究 | Whiteford, K. L. | N/A | Musical training does not enhance neural sound encoding at early stages of the auditory system: A large-scale multisite investigation | |
| 脑室周围及深部白质高信号阈值在衰老中的变化：指数级进展、认知衰退及神经解剖结构萎缩 | Gupta, N. K. | N/A | Periventricular and Deep White Matter Hyperintensity Thresholds in Aging: Exponential Progression, Cognitive Decline, and Neuroanatomic Atrophy | |
| 有药物使用障碍家族史的青年大脑活动动态的性别特异性差异 | Schilling, L. S. | N/A | Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder | |
| 整合素激活耶尔森菌蛋白入侵素维持原代上皮细胞的长期扩展，形成二维类器官片层 | Wijnakker, J. | N/A | Integrin-activating Yersinia protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets | |
| 小鼠CDK2的不同剪接异构体在有丝分裂和减数分裂过程中发挥功能冗余作用 | Palmer, N. | N/A | Differential splice isoforms of mouse CDK2 play functionally redundant roles during mitotic and meiotic division | |
| 哥斯达黎加生态系统服务付费计划的大规模恢复 | Delgado, G. L. | N/A | Large-scale recovery in Costa Rica's Payment for Ecosystem Service Program | |
| 引入白三叶草（Trifolium repens L.）后抗旱策略的演变 | Hendrickson, B. T. | N/A | Evolution of drought resistance strategies following the introduction of white clover (Trifolium repens L.) | |
| 利用牛津纳米孔长读长测序技术进行生态基因组学实践训练的工作流程 | Foster, R. | N/A | A workflow for practical training in ecological genomics using Oxford Nanopore long-read sequencing | |
| 多组学视角下的人类健康：狩猎采集者、农牧民与西方都市人群的肠道微生物群 | Singh, H. | N/A | Multiomic Insights into Human Health: Gut Microbiomes of Hunter-Gatherer, Agropastoral, and Western Urban Populations | |
| 物理机制揭示了细菌在鞭毛数量超过临界值时减速的现象 | Tatulea-Codrean, M. | N/A | Physical mechanism reveals bacterial slowdown above a critical number of flagella | |
| 抗生素前与抗生素后时代：对耐药性历史传播的洞察 | Cazares, A. | N/A | Pre and Post antibiotic epoch: insights into the historical spread of antimicrobial resistance | |
| 热应激使斑马鱼胚胎对神经毒性和心脏毒性更加敏感。 | Haapanen-Saaristo, A.-M. | N/A | Heat stress sensitizes zebrafish embryos to neurological and cardiac toxicity. | |
| 灵长类尾状核在多模态决策中的独特神经网络及其关键作用 | ZENG, Z. | N/A | Distinct neural manifolds and critical roles of primate caudate nucleus in multimodal decision-making | |
| GC含量对沿物种形成连续体分化区域形成的贡献 | Ke, F. | N/A | Contribution of GC content to differentiated region formation along a speciation continuum | |
| 神经元自噬体被转运至星形胶质细胞进行降解。 | Linda, K. | N/A | Neuronal autophagosomes are transported to astrocytes for degradation | |
| 权力不对称破坏了社会困境中的互惠合作 | Colnaghi, M. | N/A | Power asymmetry destabilizes reciprocal cooperation in social dilemmas | |
| 从影响力指标和开放科学到传播研究：记者对学术争议的认知 | Fleerackers, A. | N/A | From impact metrics and open science to communicating research: Journalists' awareness of academic controversies | |
| 波多黎各非裔后裔的基因血统展现了非洲散居人口多样的历史背景。 | Nieves-Colon, M. A. | N/A | Genetic ancestry in Puerto Rican Afro-descendants illustrates diverse histories of African diasporic populations | |
| 主要抑郁症的基因年龄差距估计（GAGE）：基于基因表达的惩罚性生物年龄模型 | Li, Y. | N/A | Gene Age Gap Estimate (GAGE) for major depressive disorder: a penalized biological age model using gene expression | |
| 靶向FOXO4-p53相互作用的肽类抑制剂，诱导衰老癌细胞特异性凋亡 | Kang, D. | N/A | Peptide inhibitors targeting FOXO4-p53 interactions and inducing senescent cancer cell-specific apoptosis | |
| 优化针对SARS-CoV-2变种的中和抗体的高通量多重检测方法。 | Ashley, C. L. | N/A | Optimisation of a multiplexed, high throughput assay to measure neutralising antibodies against SARS-CoV-2 variants. | |
| 沙门氏菌中的RNase III通过降低宿主免疫反应来增强细菌的致病性。 | CHAN, K.-w. B. | N/A | RNase III in Salmonella Enteritidis enhances bacterial virulence by reducing host immune responses | |
| 细菌通过趋同进化对宿主生态位依赖性营养物质的可用性进行代谢重塑 | Pickering, A. | N/A | Bacterial metabolic remodelling by convergent evolution in response to host niche-dependent nutrient availability | |
| 丝状蓝藻中的昼夜表达动力学 | Kennedy, S. J. | N/A | Diel expression dynamics in filamentous cyanobacteria | |
| 化学遗传相互作用阐明在感染期间控制结核病抗生素效力的途径 | Oluoch, P. O. | N/A | Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection | |
| KatG在msr缺失的鼠伤寒沙门氏菌中抵御H2O2应激的补偿作用 | Lalhmangaihzuali, L. | N/A | Compensatory role of KatG in defending H2O2 stress in msr deletion strain of Salmonella Typhimurium | |
| 在埃希氏大肠杆菌菌株中，利用微型核酸酶TnpB、IscB和enIscB进行基因编辑的特征分析 | Li, Q. | N/A | Characterization the gene editing with miniature nucleases TnpB, IscB and enIscB in Escherichia coli strains | |
| 反硝化除磷生物反应器中一氧化二氮的生成、机理及建模 | Farmer, M. | N/A | Nitrous oxide production, mechanisms, and modeling from a denitrifying phosphorus removal bioreactor | |
| 微生物代谢酶、途径及微生物宿主在废水中共代谢降解有机微污染物中的作用 | Lyu, B. | N/A | Microbial Metabolic Enzymes, Pathways and Microbial Hosts for Co-Metabolic Degradation of Organic Micropollutants in Wastewater | |
| 与克罗恩病相关的E. coli采用不同的策略来定殖巨噬细胞。 | Bruder, E. | N/A | E. coli associated with Crohn's disease exhibit distinct strategies to colonize macrophages | |
| TgGloL是一种非典型的含甘油醛/挥发性有机化合物（VOC）结构域的顶质体蛋白，对弓形虫的生长至关重要。 | Sanchez, S. G. | N/A | TgGloL is an atypical glyoxalase/VOC domain-containing apicoplast protein that is important for the growth of Toxoplasma | |
| 好氧颗粒形成过程中及进水改造后Accumulibacter及其邻近群落表达的多条胞外聚合物途径 | Cardona, L. | N/A | Multiple extracellular polymeric substances pathways expressed by Accumulibacter and the flanking community during aerobic granule formation and after influent modification | |
| 军团菌肺炎铜耐药性：遗传因素和宿主细胞的作用。 | Cameron, G. | N/A | Copper resistance in Legionella pneumophila: role of genetic factors and host cells. | |
| USP37通过TRAIP防止应激复制体过早解体。 | Kochenova, O. V. | N/A | USP37 prevents premature disassembly of stressed replisomes by TRAIP | |
| 通过测序进行全基因组RNA-蛋白质相互作用图谱绘制 | Qi, Z. | N/A | Genome-Wide Mapping of RNA-Protein Associations via Sequencing | |
| 通过tRNA剪切，将tRNA同工解码器重新用于非经典功能 | Bhatter, N. | N/A | Repurposing tRNA isodecoders for non-canonical functions via tRNA cleavage | |
| 神经生长因子trans-Banglene的蛋白质组学研究揭示了其与铁稳态的潜在联系 | Gunawardana, P. W. | N/A | Proteomic Investigation of Neurotrophic trans-Banglene Reveals Potential Link to Iron Homeostasis | |
| 选择性多腺苷酸化调节因子CFIm25促进巨噬细胞分化并激活NF-κβ通路 | Mukherjee, S. | N/A | The alternative polyadenylation regulator CFIm25 promotes macrophage differentiation and activates the NF-κβ pathway | |
| SARS-CoV-2 KP.3与ACE2之间增强亲和力的上位效应的结构和分子基础 | Feng, L. | N/A | Structural and molecular basis of the epistasis effect in enhanced affinity between SARS-CoV-2 KP.3 and ACE2 | |
| 使用CLEANSER对单细胞CRISPR筛选中的环境gRNA进行特征描述和生物信息学过滤 | Liu, S. | N/A | Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER | |
| LevSeq：快速生成序列功能数据，用于定向进化和机器学习 | Long, Y. | N/A | LevSeq: Rapid Generation of Sequence-Function Data for Directed Evolution and Machine Learning | |
| 用于生物组织中单个细胞类型的全面分子图谱的关联成像 | Yang, M. | N/A | Correlative Imaging for Comprehensive Molecular Mapping of Individual Cell Types in Biological Tissues | |
| 辣椒疫霉效应蛋白AVR3a11的动力学确认了核心WY结构域的折叠 | Tolchard, J. | N/A | Dynamics in the Phytophthora capsici effector AVR3a11 confirm the core WY domain fold | |
| LEA_4基序单独作用并与协同的共溶质结合，以在脱水过程中保护不稳定的酶。 | Nicholson, V. | N/A | LEA_4 motifs function alone and in conjunction with synergistic cosolutes to protect a labile enzyme during desiccation | |
| 具有超广底物谱的PL35家族糖胺聚糖裂解酶的晶体结构与催化机制 | Wei, L. | N/A | Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum | |
| 通过冷冻电子显微镜观察铁蛋白的有机-无机界面 | Sen, S. | N/A | Observation of the protein-inorganic interface of ferritin by cryo-electron microscopy | |
| 甜蜜的科学：利用光学衍射断层成像技术探究果糖和葡萄糖对棕色脂肪细胞分化的影响 | Anantha, P. | N/A | Sweet science: Exploring the impact of fructose and glucose on brown adipocyte differentiation using optical diffraction tomography | |
| 一种新型极端嗜盐绿藻——太平洋衣藻（Chlamydomonas pacifica）的描述及其作为生物技术宿主的潜力 | Dutra Molino, J. V. | N/A | Description of a novel extremophile green algae, Chlamydomonas pacifica, and its potential as a biotechnology host | |
| 线粒体呼吸链的细胞内结构 | Waltz, F. | N/A | In-cell architecture of the mitochondrial respiratory chain | |
| 从MetaCore网络中提取的成纤维细胞特异性蛋白质-蛋白质相互作用与心肌纤维化相关 | Frahm, K. M. | N/A | Fibroblast-specific protein-protein interactions for myocardial fibrosis from MetaCore network | |
| 一个3D子宫内膜芯片揭示了胚胎来源因子CAPG和PDI在胚胎-子宫内膜交流中的作用 | Tinning, H. | N/A | A 3D endometrium-on-a-chip reveals the role of conceptus-derived factors CAPG and PDI in conceptus-endometrial communication | |
| 多基因障碍阻止性染色体转变 | Muralidhar, P. | N/A | Polygenic barriers to sex chromosome turnover | |
| 在患者层面建模意识障碍揭示了网络对诊断的影响与局部节点参数在预后中的作用 | Zonca, L. | N/A | Modeling disorders of consciousness at the patient level reveals the network's influence on the diagnosis vs the local node parameters role in prognosis | |
| # BioRxiv 2024-09-04 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 染色质阅读器Dido3是调控B细胞分化基因网络的调节因子。 | Gutierrez del Burgo, F. | N/A | The chromatin reader Dido3 is a regulator of the gene network that controls B cell differentiation | |
| 黄矢车菊（Centaurea solstitialis）的染色体规模参考基因组和基于RAD的遗传图谱揭示了与入侵性状相关的潜在结构变异和数量性状位点（QTLs）。 | Reatini, B. | N/A | Chromosome-scale reference genome and RAD-based genetic map of yellow starthistle (Centaurea solstitialis) reveal putative structural variation and QTLs associated with invader traits | |
| Shewanella fidelis 3313 运动性和生物膜形成的噬菌体调控：对 Ciona robusta 肠道定殖动态的影响 | Natarajan, O. | N/A | Prophage regulation of Shewanella fidelis 3313 motility and biofilm formation: implications for gut colonization dynamics in Ciona robusta | |
| 在没有监督的情况下，发现蒙古沙鼠家族特有的发声使用 | Peterson, R. E. | N/A | Unsupervised discovery of family specific vocal usage in the Mongolian gerbil | |
| 动作电位的消失会诱导神经元之间的电耦合 | Schloetter, M. | N/A | Annihilation of action potentials induces electrical coupling between neurons | |
| 通过灵长类抓握回路中与姿势相关的活动，实现对手部假肢的精确神经控制。 | Agudelo-Toro, A. | N/A | Accurate neural control of a hand prosthesis by posture-related activity in the primate grasping circuit | |
| M3NetFlow：一种用于综合多组学数据分析的新型多尺度多跳图AI模型 | Zhang, H. | N/A | M3NetFlow: A novel multi-scale multi-hop graph AI model for integrative multi-omic data analysis | |
| GluK1海人藻酸受体外显子9剪接插入的功能意义 | Dhingra, S. | N/A | Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors | |
| PARP14/TARG1调控的RACK1 MARylation循环驱动卵巢癌细胞中的应激颗粒动态变化 | Challa, S. | N/A | A PARP14/TARG1-Regulated RACK1 MARylation Cycle Drives Stress Granule Dynamics in Ovarian Cancer Cells | |
| 全球浮游植物Bathycoccus的生物和基因组资源：遗传多样性和主要结构变异的见解 | Dennu, L. | N/A | Biological and genomic resources for the cosmopolitan phytoplankton Bathycoccus: Insights into genetic diversity and major structural variations | |
| dact1/2 调控非经典 Wnt 信号通路及胚胎期趋同延伸和颅面形态发生过程中 calpain 8 的遗传需求 | Carroll, S. H. | N/A | Genetic requirement of dact1/2 to regulate noncanonical Wnt signaling and calpain 8 during embryonic convergent extension and craniofacial morphogenesis | |
| 具有疾病表现型的人类进化新基因揭示了由适应性创新和性选择塑造的功能富集模式。 | Chen, J. | N/A | Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection. | |
| 电子自旋极化与电荷动力学在蛋白质功能中的作用 | Vyas, P. | N/A | The Role of Electron Spin-Polarizability and Charge Dynamics in Protein Function | |
| 欧亚小鳊（鲤科：Phoxinus phoxinus）的染色体水平、单倍型解析的基因组组装与注释提供了单倍型多样性的证据。 | Oriowo, T. O. | N/A | A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae: Phoxinus phoxinus) provide evidence of haplotype diversity | |
| 双酚A的质子转移对于激活核外启动的雌激素受体信号传导是必需的。 | Medina-Gali, R. M. | N/A | PROTON TRANSFER FROM BISPHENOL-A IS REQUIRED TO ACTIVATE EXTRANUCLEAR-INITIATED ESTROGEN RECEPTOR SIGNALING | |
| 可解释的多模态机器学习（IMML）框架揭示了远端感觉运动多发性神经病变的病理特征。 | Nguyen, P. B. | N/A | The Interpretable Multimodal Machine Learning (IMML) framework reveals pathological signatures of distal sensorimotor polyneuropathy | |
| 药物适应的癌细胞系中的抗药性模式反映了临床肿瘤中复杂的进化过程。 | Grimsley, H. E. | N/A | Resistance patterns in drug-adapted cancer cell lines reflect complex evolution in clinical tumors | |
| 干扰抑制仅在视网膜坐标中运作 | Ilksoy, Y. A. | N/A | Distractor suppression operates exclusively in retinotopic coordinates | |
| 抑制性神经元中神经纤毛蛋白-2表达失调会损害海马回路发育，导致自闭症-癫痫表型 | Subramanian, D. | N/A | Dysregulation of Neuropilin-2 Expression in Inhibitory Neurons Impairs Hippocampal Circuit Development Leading to Autism-Epilepsy Phenotype | |
| 通过从选择性繁殖小鼠的肠道微生物群中提取的罗伊氏乳杆菌增强驯化效果 | Biswa, B. B. | N/A | Enhanced tameness by Limosilactobacillus reuteri from gut microbiota of selectively bred mice | |
| 2P-NucTag：用于功能性识别皮层神经元分子分析的按需光标记技术 | Shi, J. | N/A | 2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons | |
| 通过神经网络收敛揭示的视觉人类前额叶激活的文本相关功能 | Shoham, A. | N/A | Text-related functionality of visual human pre-frontal activations revealed through neural network convergence | |
| 当前的基因组深度学习架构能够在不同草种之间进行泛化，但不能在等位基因之间进行泛化。 | Wrightsman, T. | N/A | Current genomic deep learning architectures generalize across grass species but not alleles | |
| 整合脊椎动物神经管空间和时间模式化的顺式调控逻辑 | Zhang, I. | N/A | The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube | |
| 母体肥胖可能通过增加DNMTs（DNA甲基转移酶）导致卵母细胞基因组高甲基化，从而扰乱后代的新陈代谢。 | Chao, S. | N/A | Maternal obesity may disrupt offspring metabolism by inducing oocyte genome hyper-methylation via increased DNMTs | |
| 通过大型语言模型预测TET和DNMT3敲除突变体中的差异甲基化胞嘧啶 | sereshki, s. | N/A | Predicting Differentially Methylated Cytosines in TET and DNMT3 Knockout Mutants via a Large Language Model | |
| 抗体依赖性增强作用在登革病毒感染的Wistar大鼠中的作用，作为登革热小鼠模型 | Wihanto, L. | N/A | Role of antibody-dependent enhancement in DENV-infected Wistar rats as a dengue murine model | |
| 修正关系估计中的模型设定误差 | Jewett, E. M. | N/A | Correcting model misspecification in relationship estimates | |
| 脂肪细胞中同源结构域转录因子在产热中的作用：对人类UCP1物种特异性和保守调控元件的见解 | B. Toth, B. | N/A | Homeodomain transcription factors in adipocyte thermogenesis: insights into the species-specific and conserved regulatory elements of human UCP1 | |
| 全基因组条件性降解标签文库用于功能基因组学研究 | Gameiro, E. | N/A | Genome-wide conditional degron libraries for functional genomics | |
| 一种高效预测自然物体感知相似度的高通量方法 | Kaniuth, P. | N/A | A high-throughput approach for the efficient prediction of perceived similarity of natural objects | |
| 酒精通过刺激AMPK介导的对TORC1、p70/S6K及核糖体生物合成的抑制，诱导神经嵴中p53介导的凋亡。 | Huang, Y. | N/A | Alcohol induces p53-mediated apoptosis in neural crest by stimulating the AMPK-mediated suppression of TORC1, p70/S6K, and ribosomal biogenesis. | |
| 在社会变形虫Dictyostelium discoideum中，支配等级是线性的但较为浅显。 | Broersma, C. M. E. | N/A | Dominance hierarchies are linear but shallow in the social amoeba Dictyostelium discoideum. | |
| 一个表示紧张性动作电位放电序列的数学序列 | Keum, D. | N/A | A Mathematical Sequence Representing Tonic Action Potential Spike Trains | |
| 食肉真菌少孢节丛孢的捕食装置是一种表型系统，用于分离热诱导的过量铁 | Zhou, J. | N/A | Trapping Devices of Carnivorous fungus Arthrobotrys oligospora is a Phenotypic System for Separating Thermally-Induced Excess Irons | |
| 纺织结构自动模型发现：经编面料的独特力学特征 | McCulloch, J. A. | N/A | Automated model discovery for textile structures:The unique mechanical signature of warp knitted fabrics | |
| 一氧化碳驱动的生物乙醇生产通过依赖钨的催化剂进行。 | Lemaire, O. N. | N/A | Carbon monoxide-driven bioethanol production operates via a tungsten-dependent catalyst | |
| 非周期性和振荡系统构成了人类领域一般认知的基础。 | Lu, R. | N/A | Aperiodic and oscillatory systems underpinning human domain-general cognition | |
| 用于斑马鱼异种移植模型的自动微量注射技术 | Ding, Y. | N/A | Automated microinjection for zebrafish xenograft models | |
| 非洲丽鱼（Astatotilapia burtoni）的面部和体色与社会地位有关。 | Peros, M. | N/A | Facial and body colouration are linked to social rank in the African cichlid, Astatotilapia burtoni | |
| 葡萄糖激酶活性控制着β细胞的亚群，这些亚群交替引导胰岛Ca2+振荡。 | Jin, E. | N/A | Glucokinase activity controls subpopulations of β-cells that alternately lead islet Ca2+ oscillations | |
| 穴样蛋白组装体使一片双层膜叶发生移位，以组织和弯曲膜结构。 | Doktorova, M. | N/A | Caveolin assemblies displace one bilayer leaflet to organize and bend membranes | |
| 乳腺癌基因表达的综合元分析 | Nwosu, I. O. | N/A | A Comprehensive Meta-Analysis of Breast Cancer Gene Expression | |
| 在乙醇-CPP中追求再巩固：不同条件下的记忆再激活并未触发不稳定性 | Zacouteguy Boos, F. | N/A | Pursuing reconsolidation in ethanol-CPP: memory reactivation in different conditions did not trigger destabilization | |
| 远端超级增强子驱动癌细胞中异常的CXCL13表达，通过CXCR5-CXCL13轴促进生长并导致p53失调 | Gothwal, S. K. | N/A | Distal super-enhancer drives aberrant CXCL13 expression in Cancer cells driving growth and p53 dysregulation via CXCR5-CXCL13 axis | |
| 人工自然杀伤细胞模拟系统设计，以靶向肿瘤细胞 | Chugh, V. | N/A | Design of an Artificial Natural Killer Cell Mimicking System to Target Tumour Cells | |
| 多感官方法在心理意象中的应用：比较运动、视觉和听觉意象的ALE元分析 | Van Caenegem, E. E. | N/A | Multisensory approach in Mental Imagery: ALE meta-analyses comparing Motor, Visual and Auditory Imagery | |
| 深度对比学习实现了全基因组的虚拟筛选。 | Jia, Y. | N/A | Deep contrastive learning enables genome-wide virtual screening | |
| 一种结合计算机视觉和DNA条形码技术的无脊椎动物生物监测混合方法 | Blair, J. D. | N/A | A hybrid approach to invertebrate biomonitoring using computer vision and DNA metabarcoding | |
| 钠泄漏通道NALCN受神经元SNARE复合体蛋白的调控。 | Usher, S. G. | N/A | The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins | |
| 单细胞多组学揭示了物种特异性发育速度差异背后的糖原代谢差异 | de la Porte, A. | N/A | Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development | |
| 皮下注射超声和X射线可成像的载有阿霉素的热敏水凝胶与游离药物在小猪体内的成像和药代动力学比较 | Delgado, J. F. | N/A | In vivo Imaging and Pharmacokinetics of Percutaneously Injected Ultrasound and X-ray Imageable Thermosensitive Hydrogel loaded with Doxorubicin versus Free Drug in Swine | |
| 驱动哺乳动物脊髓内运动神经元特异性病毒载体表达的顺式调控元件 | Nagy, M. A. | N/A | Cis-regulatory elements driving motor neuron-restricted viral payload expression within the mammalian spinal cord | |
| 利用CRISPR-CAS9介导的LACZ基因编辑优化以马铃薯皮为葡萄糖源的工程大肠杆菌中脂肪酶的生产与特性分析 | Minari, J. B. | N/A | CRISPR-CAS9 MEDIATED EDITING OF THE LACZ GENE FOR OPTIMIZING LIPASE PRODUCTION AND CHARACTERIZATION IN ENGINEERED ESCHERICHIA COLI USING POTATO PEEL AS A GLUCOSE SOURCE | |
| 系统综述：微生物活动在养分循环与转化中的作用及其对土壤肥力和作物生产力的影响 | Zeleke, T. B. | N/A | Systematic Review on the Role of Microbial Activities on Nutrient Cycling and Transformation Implication for Soil Fertility and Crop Productivity | |
| IgSeqR：一种从非选择性RNA测序数据中识别、组装和表征全长肿瘤免疫球蛋白转录本的协议 | Bryant, D. | N/A | IgSeqR: a protocol for the identification, assembly, and characterization of full-length tumor Immunoglobulin transcripts from unselected RNA sequencing data | |
| 时间基因组动力学塑造多发性骨髓瘤的临床轨迹 | MAURA, F. | N/A | Temporal Genomic Dynamics Shape Clinical Trajectory in Multiple Myeloma | |
| 一项多维度的泛癌分析揭示了CDKN1A作为免疫学和预后生物标志物的身份 | Shi, L. | N/A | A multidimensional Pan-cancer analysis of CDKN1A identifies CDKN1A as an Immunological and Prognostic Biomarker | |
| 视觉注意对阿拉伯字母识别及阅读习得的影响 | Ghandour, A. | N/A | The influence of visual attention on letter recognition and reading acquisition in Arabic | |
| 音乐训练并不增强听觉系统早期阶段的神经声音编码：一项大规模多中心研究 | Whiteford, K. L. | N/A | Musical training does not enhance neural sound encoding at early stages of the auditory system: A large-scale multisite investigation | |
| 脑室周围和深部白质高信号阈值在衰老中的变化：指数级进展、认知衰退与神经解剖学萎缩 | Gupta, N. K. | N/A | Periventricular and Deep White Matter Hyperintensity Thresholds in Aging: Exponential Progression, Cognitive Decline, and Neuroanatomic Atrophy | |
| 有物质使用障碍家族史的青少年大脑活动动态的性别特异性差异 | Schilling, L. S. | N/A | Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder | |
| 整合素激活耶尔森菌蛋白Invasin维持原代上皮细胞长期扩展为二维类器官片 | Wijnakker, J. | N/A | Integrin-activating Yersinia protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets | |
| 小鼠CDK2的不同剪接异构体在有丝分裂和减数分裂过程中发挥功能冗余作用 | Palmer, N. | N/A | Differential splice isoforms of mouse CDK2 play functionally redundant roles during mitotic and meiotic division | |
| 哥斯达黎加生态系统服务付费计划的大规模恢复 | Delgado, G. L. | N/A | Large-scale recovery in Costa Rica's Payment for Ecosystem Service Program | |
| 引入白三叶草（Trifolium repens L.）后抗旱策略的演变 | Hendrickson, B. T. | N/A | Evolution of drought resistance strategies following the introduction of white clover (Trifolium repens L.) | |
| 使用牛津纳米孔长读长测序进行生态基因组学实践培训的工作流程 | Foster, R. | N/A | A workflow for practical training in ecological genomics using Oxford Nanopore long-read sequencing | |
| 多组学视角下的人类健康：狩猎采集者、农牧民和西方城市人口的肠道微生物群 | Singh, H. | N/A | Multiomic Insights into Human Health: Gut Microbiomes of Hunter-Gatherer, Agropastoral, and Western Urban Populations | |
| 物理机制揭示了细菌在鞭毛数量超过临界值时减速的现象 | Tatulea-Codrean, M. | N/A | Physical mechanism reveals bacterial slowdown above a critical number of flagella | |
| 抗生素前与抗生素后时代：对抗生素耐药性历史传播的洞察 | Cazares, A. | N/A | Pre and Post antibiotic epoch: insights into the historical spread of antimicrobial resistance | |
| 热应激使斑马鱼胚胎对神经毒性和心脏毒性更加敏感。 | Haapanen-Saaristo, A.-M. | N/A | Heat stress sensitizes zebrafish embryos to neurological and cardiac toxicity. | |
| 灵长类尾状核在多模态决策中的独特神经结构及其关键作用 | ZENG, Z. | N/A | Distinct neural manifolds and critical roles of primate caudate nucleus in multimodal decision-making | |
| GC含量对物种形成连续体中分化区域形成的贡献 | Ke, F. | N/A | Contribution of GC content to differentiated region formation along a speciation continuum | |
| 神经元自噬体被运输到星形胶质细胞中进行降解 | Linda, K. | N/A | Neuronal autophagosomes are transported to astrocytes for degradation | |
| 权力不对称破坏了社会困境中的互惠合作 | Colnaghi, M. | N/A | Power asymmetry destabilizes reciprocal cooperation in social dilemmas | |
| 从影响力指标和开放科学到传播研究：记者对学术争议的认知 | Fleerackers, A. | N/A | From impact metrics and open science to communicating research: Journalists' awareness of academic controversies | |
| 波多黎各非裔后裔的基因血统展示了非洲散居人口的多样历史。 | Nieves-Colon, M. A. | N/A | Genetic ancestry in Puerto Rican Afro-descendants illustrates diverse histories of African diasporic populations | |
| 主要抑郁症的基因年龄差距估计（GAGE）：使用基因表达的惩罚性生物年龄模型 | Li, Y. | N/A | Gene Age Gap Estimate (GAGE) for major depressive disorder: a penalized biological age model using gene expression | |
| 靶向FOXO4-p53相互作用的肽类抑制剂，诱导衰老癌细胞特异性凋亡 | Kang, D. | N/A | Peptide inhibitors targeting FOXO4-p53 interactions and inducing senescent cancer cell-specific apoptosis | |
| 优化一种多重、高通量检测方法以测量针对SARS-CoV-2变种的中和抗体。 | Ashley, C. L. | N/A | Optimisation of a multiplexed, high throughput assay to measure neutralising antibodies against SARS-CoV-2 variants. | |
| 沙门氏菌中的RNase III通过降低宿主免疫反应来增强细菌的致病性。 | CHAN, K.-w. B. | N/A | RNase III in Salmonella Enteritidis enhances bacterial virulence by reducing host immune responses | |
| 细菌代谢的重塑通过趋同进化对宿主生态位依赖的营养物质可用性做出反应 | Pickering, A. | N/A | Bacterial metabolic remodelling by convergent evolution in response to host niche-dependent nutrient availability | |
| 丝状蓝藻中的昼夜表达动力学 | Kennedy, S. J. | N/A | Diel expression dynamics in filamentous cyanobacteria | |
| 化学遗传相互作用阐明感染期间控制结核病抗生素疗效的途径 | Oluoch, P. O. | N/A | Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection | |
| KatG在msr缺失型沙门氏菌Typhimurium中抵御H2O2应激的补偿作用 | Lalhmangaihzuali, L. | N/A | Compensatory role of KatG in defending H2O2 stress in msr deletion strain of Salmonella Typhimurium | |
| 在埃希氏大肠杆菌菌株中，对使用微型核酸酶TnpB、IscB和enIscB进行基因编辑的特性进行了研究。 | Li, Q. | N/A | Characterization the gene editing with miniature nucleases TnpB, IscB and enIscB in Escherichia coli strains | |
| 一株脱氮除磷生物反应器中氧化亚氮的产生、机理及模型化研究 | Farmer, M. | N/A | Nitrous oxide production, mechanisms, and modeling from a denitrifying phosphorus removal bioreactor | |
| 微生物代谢酶、途径及共代谢降解有机微污染物所涉及的微生物宿主在废水处理中的作用 | Lyu, B. | N/A | Microbial Metabolic Enzymes, Pathways and Microbial Hosts for Co-Metabolic Degradation of Organic Micropollutants in Wastewater | |
| 与克罗恩病相关的E. coli表现出独特的策略来定殖巨噬细胞 | Bruder, E. | N/A | E. coli associated with Crohn's disease exhibit distinct strategies to colonize macrophages | |
| TgGloL是一种非典型的含甘油醛/挥发性有机化合物（VOC）域的顶质体蛋白，对弓形虫的生长至关重要。 | Sanchez, S. G. | N/A | TgGloL is an atypical glyoxalase/VOC domain-containing apicoplast protein that is important for the growth of Toxoplasma | |
| 好氧颗粒形成过程中及进水改造后Accumulibacter及其相邻群落表达的多条胞外聚合物途径 | Cardona, L. | N/A | Multiple extracellular polymeric substances pathways expressed by Accumulibacter and the flanking community during aerobic granule formation and after influent modification | |
| 铜对军团菌肺炎的抗性：遗传因素和宿主细胞的作用。 | Cameron, G. | N/A | Copper resistance in Legionella pneumophila: role of genetic factors and host cells. | |
| USP37通过TRAIP防止应激复制体过早解体 | Kochenova, O. V. | N/A | USP37 prevents premature disassembly of stressed replisomes by TRAIP | |
| 通过测序进行全基因组RNA-蛋白质相互作用图谱绘制 | Qi, Z. | N/A | Genome-Wide Mapping of RNA-Protein Associations via Sequencing | |
| 通过tRNA剪切重新利用tRNA同义解码器用于非经典功能 | Bhatter, N. | N/A | Repurposing tRNA isodecoders for non-canonical functions via tRNA cleavage | |
| 神经滋养性反式-Banglene的蛋白质组学研究揭示了与铁稳态的潜在联系 | Gunawardana, P. W. | N/A | Proteomic Investigation of Neurotrophic trans-Banglene Reveals Potential Link to Iron Homeostasis | |
| 选择性多腺苷酸化调节因子CFIm25促进巨噬细胞分化并激活NF-κβ通路 | Mukherjee, S. | N/A | The alternative polyadenylation regulator CFIm25 promotes macrophage differentiation and activates the NF-κβ pathway | |
| SARS-CoV-2 KP.3与ACE2之间增强亲和力的上位效应的结构和分子基础 | Feng, L. | N/A | Structural and molecular basis of the epistasis effect in enhanced affinity between SARS-CoV-2 KP.3 and ACE2 | |
| 利用CLEANSER对单细胞CRISPR筛选中的环境gRNA进行特征化与生物信息学过滤 | Liu, S. | N/A | Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER | |
| LevSeq：快速生成序列功能数据，用于定向进化和机器学习 | Long, Y. | N/A | LevSeq: Rapid Generation of Sequence-Function Data for Directed Evolution and Machine Learning | |
| 用于生物组织中单个细胞类型的全面分子图谱的关联成像 | Yang, M. | N/A | Correlative Imaging for Comprehensive Molecular Mapping of Individual Cell Types in Biological Tissues | |
| 辣椒疫霉效应子AVR3a11的动力学分析证实了核心WY结构域的折叠 | Tolchard, J. | N/A | Dynamics in the Phytophthora capsici effector AVR3a11 confirm the core WY domain fold | |
| LEA_4基序单独作用并与协同共溶质结合，以在脱水过程中保护不稳定的酶。 | Nicholson, V. | N/A | LEA_4 motifs function alone and in conjunction with synergistic cosolutes to protect a labile enzyme during desiccation | |
| 具有超广底物谱的PL35家族糖胺聚糖裂解酶的晶体结构与催化机制 | Wei, L. | N/A | Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum | |
| 通过冷冻电子显微镜观察铁蛋白的有机-无机界面 | Sen, S. | N/A | Observation of the protein-inorganic interface of ferritin by cryo-electron microscopy | |
| 甜蜜的科学：利用光学衍射断层成像技术探究果糖和葡萄糖对棕色脂肪细胞分化的影响 | Anantha, P. | N/A | Sweet science: Exploring the impact of fructose and glucose on brown adipocyte differentiation using optical diffraction tomography | |
| 一种新型极端嗜盐绿色藻类——太平洋衣藻（Chlamydomonas pacifica）的描述及其作为生物技术宿主的潜力 | Dutra Molino, J. V. | N/A | Description of a novel extremophile green algae, Chlamydomonas pacifica, and its potential as a biotechnology host | |
| 线粒体呼吸链的细胞内结构 | Waltz, F. | N/A | In-cell architecture of the mitochondrial respiratory chain | |
| 从MetaCore网络中提取的成纤维细胞特异性蛋白质-蛋白质相互作用与心肌纤维化相关 | Frahm, K. M. | N/A | Fibroblast-specific protein-protein interactions for myocardial fibrosis from MetaCore network | |
| 一个三维子宫内膜芯片揭示了胚胎源性因子CAPG和PDI在胚胎-子宫内膜交流中的作用 | Tinning, H. | N/A | A 3D endometrium-on-a-chip reveals the role of conceptus-derived factors CAPG and PDI in conceptus-endometrial communication | |
| 多基因障碍阻止性染色体转变 | Muralidhar, P. | N/A | Polygenic barriers to sex chromosome turnover | |
| 在患者层面建模意识障碍揭示了网络对诊断的影响与局部节点参数对预后的作用 | Zonca, L. | N/A | Modeling disorders of consciousness at the patient level reveals the network's influence on the diagnosis vs the local node parameters role in prognosis | |
| # BioRxiv 2024-09-04 Papers |
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|